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Network neighborhood for query Sequence : TTF2_MOUSE

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TTF2_MOUSE
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TTF2_HUMAN
θ value	0 (rank : 1)	NC score	0.940595 (rank : 2)
Query Neighborhood Hits	364	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	364	Target Neighborhood Hits	364	Shared Neighborhood Hits	364
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRA3_MOUSE
θ value	1.98146e-39 (rank : 3)	NC score	0.755883 (rank : 26)
Query Neighborhood Hits	364	Target Neighborhood Hits	267	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
θ value	7.52953e-39 (rank : 4)	NC score	0.752928 (rank : 27)
Query Neighborhood Hits	364	Target Neighborhood Hits	265	Shared Neighborhood Hits	43
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMCA1_MOUSE
θ value	5.0505e-35 (rank : 5)	NC score	0.818380 (rank : 7)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA5_MOUSE
θ value	4.27553e-34 (rank : 6)	NC score	0.817442 (rank : 8)
Query Neighborhood Hits	364	Target Neighborhood Hits	80	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA1_HUMAN
θ value	9.52487e-34 (rank : 7)	NC score	0.818727 (rank : 6)
Query Neighborhood Hits	364	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_HUMAN
θ value	9.52487e-34 (rank : 8)	NC score	0.816859 (rank : 9)
Query Neighborhood Hits	364	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMRCD_HUMAN
θ value	6.82597e-32 (rank : 9)	NC score	0.828509 (rank : 3)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD1_HUMAN
θ value	4.89182e-30 (rank : 10)	NC score	0.793120 (rank : 17)
Query Neighborhood Hits	364	Target Neighborhood Hits	337	Shared Neighborhood Hits	76
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
θ value	1.4233e-29 (rank : 11)	NC score	0.792723 (rank : 18)
Query Neighborhood Hits	364	Target Neighborhood Hits	235	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_MOUSE
θ value	1.85889e-29 (rank : 12)	NC score	0.793372 (rank : 16)
Query Neighborhood Hits	364	Target Neighborhood Hits	266	Shared Neighborhood Hits	64
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

BTAF1_HUMAN
θ value	7.06379e-29 (rank : 13)	NC score	0.825131 (rank : 4)
Query Neighborhood Hits	364	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD2_HUMAN
θ value	1.57365e-28 (rank : 14)	NC score	0.797339 (rank : 15)
Query Neighborhood Hits	364	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

SMRCD_MOUSE
θ value	1.57365e-28 (rank : 15)	NC score	0.824645 (rank : 5)
Query Neighborhood Hits	364	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD6_HUMAN
θ value	2.27234e-27 (rank : 16)	NC score	0.792057 (rank : 19)
Query Neighborhood Hits	364	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_MOUSE
θ value	1.92365e-26 (rank : 17)	NC score	0.789826 (rank : 22)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
θ value	3.28125e-26 (rank : 18)	NC score	0.780600 (rank : 23)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	63
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

RAD54_HUMAN
θ value	6.18819e-25 (rank : 19)	NC score	0.809046 (rank : 13)
Query Neighborhood Hits	364	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

INOC1_HUMAN
θ value	3.07116e-24 (rank : 20)	NC score	0.791748 (rank : 20)
Query Neighborhood Hits	364	Target Neighborhood Hits	181	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	8.93572e-24 (rank : 21)	NC score	0.791640 (rank : 21)
Query Neighborhood Hits	364	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

RA54B_HUMAN
θ value	5.79196e-23 (rank : 22)	NC score	0.816258 (rank : 10)
Query Neighborhood Hits	364	Target Neighborhood Hits	54	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA2_HUMAN
θ value	7.56453e-23 (rank : 23)	NC score	0.770411 (rank : 24)
Query Neighborhood Hits	364	Target Neighborhood Hits	503	Shared Neighborhood Hits	86
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RA54B_MOUSE
θ value	1.6852e-22 (rank : 24)	NC score	0.813784 (rank : 11)
Query Neighborhood Hits	364	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_MOUSE
θ value	3.75424e-22 (rank : 25)	NC score	0.804985 (rank : 14)
Query Neighborhood Hits	364	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

ERCC6_HUMAN
θ value	3.17815e-21 (rank : 26)	NC score	0.813178 (rank : 12)
Query Neighborhood Hits	364	Target Neighborhood Hits	247	Shared Neighborhood Hits	83
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA4_HUMAN
θ value	1.2077e-20 (rank : 27)	NC score	0.758405 (rank : 25)
Query Neighborhood Hits	364	Target Neighborhood Hits	597	Shared Neighborhood Hits	100
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD4_HUMAN
θ value	1.47631e-18 (rank : 28)	NC score	0.716531 (rank : 32)
Query Neighborhood Hits	364	Target Neighborhood Hits	365	Shared Neighborhood Hits	64
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.47631e-18 (rank : 29)	NC score	0.717372 (rank : 30)
Query Neighborhood Hits	364	Target Neighborhood Hits	408	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	1.63225e-17 (rank : 30)	NC score	0.713614 (rank : 33)
Query Neighborhood Hits	364	Target Neighborhood Hits	349	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	3.07829e-16 (rank : 31)	NC score	0.716710 (rank : 31)
Query Neighborhood Hits	364	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ATRX_MOUSE
θ value	6.85773e-16 (rank : 32)	NC score	0.660294 (rank : 36)
Query Neighborhood Hits	364	Target Neighborhood Hits	682	Shared Neighborhood Hits	133
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
θ value	3.40345e-15 (rank : 33)	NC score	0.639655 (rank : 37)
Query Neighborhood Hits	364	Target Neighborhood Hits	842	Shared Neighborhood Hits	149
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

SMAL1_HUMAN
θ value	9.90251e-15 (rank : 34)	NC score	0.736620 (rank : 29)
Query Neighborhood Hits	364	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	1.86753e-13 (rank : 35)	NC score	0.737191 (rank : 28)
Query Neighborhood Hits	364	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

EP400_MOUSE
θ value	2.43908e-13 (rank : 36)	NC score	0.693006 (rank : 35)
Query Neighborhood Hits	364	Target Neighborhood Hits	592	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

EP400_HUMAN
θ value	3.52202e-12 (rank : 37)	NC score	0.696326 (rank : 34)
Query Neighborhood Hits	364	Target Neighborhood Hits	556	Shared Neighborhood Hits	73
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SMOO_HUMAN
θ value	1.43324e-05 (rank : 38)	NC score	0.069495 (rank : 142)
Query Neighborhood Hits	364	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

NFH_HUMAN
θ value	2.44474e-05 (rank : 39)	NC score	0.070473 (rank : 137)
Query Neighborhood Hits	364	Target Neighborhood Hits	1242	Shared Neighborhood Hits	131
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ENAH_HUMAN
θ value	0.00020696 (rank : 40)	NC score	0.059502 (rank : 204)
Query Neighborhood Hits	364	Target Neighborhood Hits	784	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

NEIL3_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.116157 (rank : 53)
Query Neighborhood Hits	364	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NFM_MOUSE
θ value	0.000786445 (rank : 42)	NC score	0.050680 (rank : 270)
Query Neighborhood Hits	364	Target Neighborhood Hits	1159	Shared Neighborhood Hits	123
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NPBL_MOUSE
θ value	0.000786445 (rank : 43)	NC score	0.188190 (rank : 39)
Query Neighborhood Hits	364	Target Neighborhood Hits	1041	Shared Neighborhood Hits	197
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MILK1_MOUSE
θ value	0.00134147 (rank : 44)	NC score	0.061180 (rank : 192)
Query Neighborhood Hits	364	Target Neighborhood Hits	788	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

SRRM2_MOUSE
θ value	0.00175202 (rank : 45)	NC score	0.115523 (rank : 54)
Query Neighborhood Hits	364	Target Neighborhood Hits	1470	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZN318_HUMAN
θ value	0.00175202 (rank : 46)	NC score	0.089368 (rank : 97)
Query Neighborhood Hits	364	Target Neighborhood Hits	497	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

BSN_HUMAN
θ value	0.00228821 (rank : 47)	NC score	0.093156 (rank : 86)
Query Neighborhood Hits	364	Target Neighborhood Hits	1537	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NEIL3_MOUSE
θ value	0.00228821 (rank : 48)	NC score	0.109859 (rank : 59)
Query Neighborhood Hits	364	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NFM_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.056639 (rank : 222)
Query Neighborhood Hits	364	Target Neighborhood Hits	1328	Shared Neighborhood Hits	152
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TEX2_MOUSE
θ value	0.00390308 (rank : 50)	NC score	0.071175 (rank : 135)
Query Neighborhood Hits	364	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

ABCF1_HUMAN
θ value	0.00509761 (rank : 51)	NC score	0.042498 (rank : 299)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

PELP1_HUMAN
θ value	0.00509761 (rank : 52)	NC score	0.063776 (rank : 174)
Query Neighborhood Hits	364	Target Neighborhood Hits	596	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SFR11_HUMAN
θ value	0.00509761 (rank : 53)	NC score	0.117137 (rank : 52)
Query Neighborhood Hits	364	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

PPIG_HUMAN
θ value	0.00665767 (rank : 54)	NC score	0.081900 (rank : 114)
Query Neighborhood Hits	364	Target Neighborhood Hits	670	Shared Neighborhood Hits	125
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

MBB1A_HUMAN
θ value	0.00869519 (rank : 55)	NC score	0.110528 (rank : 58)
Query Neighborhood Hits	364	Target Neighborhood Hits	665	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

SFR12_HUMAN
θ value	0.00869519 (rank : 56)	NC score	0.092419 (rank : 89)
Query Neighborhood Hits	364	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

MDN1_HUMAN
θ value	0.0113563 (rank : 57)	NC score	0.098202 (rank : 73)
Query Neighborhood Hits	364	Target Neighborhood Hits	662	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

BSN_MOUSE
θ value	0.0148317 (rank : 58)	NC score	0.096310 (rank : 79)
Query Neighborhood Hits	364	Target Neighborhood Hits	2057	Shared Neighborhood Hits	138
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NTBP1_MOUSE
θ value	0.0148317 (rank : 59)	NC score	0.083279 (rank : 109)
Query Neighborhood Hits	364	Target Neighborhood Hits	528	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

RL1D1_HUMAN
θ value	0.0148317 (rank : 60)	NC score	0.102277 (rank : 68)
Query Neighborhood Hits	364	Target Neighborhood Hits	180	Shared Neighborhood Hits	55
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

ARS2_HUMAN
θ value	0.0193708 (rank : 61)	NC score	0.087517 (rank : 101)
Query Neighborhood Hits	364	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CYLC1_HUMAN
θ value	0.0193708 (rank : 62)	NC score	0.102313 (rank : 67)
Query Neighborhood Hits	364	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

JHD2C_MOUSE
θ value	0.0193708 (rank : 63)	NC score	0.048164 (rank : 281)
Query Neighborhood Hits	364	Target Neighborhood Hits	297	Shared Neighborhood Hits	52
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

MYST4_HUMAN
θ value	0.0193708 (rank : 64)	NC score	0.069127 (rank : 143)
Query Neighborhood Hits	364	Target Neighborhood Hits	671	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

RBM25_HUMAN
θ value	0.0193708 (rank : 65)	NC score	0.069630 (rank : 140)
Query Neighborhood Hits	364	Target Neighborhood Hits	682	Shared Neighborhood Hits	81
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

ARS2_MOUSE
θ value	0.0252991 (rank : 66)	NC score	0.082469 (rank : 113)
Query Neighborhood Hits	364	Target Neighborhood Hits	212	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

RENT2_HUMAN
θ value	0.0252991 (rank : 67)	NC score	0.063261 (rank : 178)
Query Neighborhood Hits	364	Target Neighborhood Hits	618	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

MAP1B_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.098820 (rank : 72)
Query Neighborhood Hits	364	Target Neighborhood Hits	977	Shared Neighborhood Hits	131
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RBP1_HUMAN
θ value	0.0330416 (rank : 69)	NC score	0.037316 (rank : 320)
Query Neighborhood Hits	364	Target Neighborhood Hits	521	Shared Neighborhood Hits	40
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SFR12_MOUSE
θ value	0.0330416 (rank : 70)	NC score	0.097716 (rank : 76)
Query Neighborhood Hits	364	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SRRM2_HUMAN
θ value	0.0330416 (rank : 71)	NC score	0.106887 (rank : 60)
Query Neighborhood Hits	364	Target Neighborhood Hits	1296	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PCLO_HUMAN
θ value	0.0431538 (rank : 72)	NC score	0.096124 (rank : 82)
Query Neighborhood Hits	364	Target Neighborhood Hits	2046	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RP1L1_HUMAN
θ value	0.0431538 (rank : 73)	NC score	0.060760 (rank : 195)
Query Neighborhood Hits	364	Target Neighborhood Hits	1072	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SFRS4_MOUSE
θ value	0.0431538 (rank : 74)	NC score	0.055168 (rank : 232)
Query Neighborhood Hits	364	Target Neighborhood Hits	406	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TEX2_HUMAN
θ value	0.0431538 (rank : 75)	NC score	0.067405 (rank : 149)
Query Neighborhood Hits	364	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TOP2A_HUMAN
θ value	0.0431538 (rank : 76)	NC score	0.035442 (rank : 332)
Query Neighborhood Hits	364	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TRHY_HUMAN
θ value	0.0431538 (rank : 77)	NC score	0.039060 (rank : 309)
Query Neighborhood Hits	364	Target Neighborhood Hits	1385	Shared Neighborhood Hits	93
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MAP1B_HUMAN
θ value	0.0563607 (rank : 78)	NC score	0.098199 (rank : 74)
Query Neighborhood Hits	364	Target Neighborhood Hits	903	Shared Neighborhood Hits	114
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MDC1_MOUSE
θ value	0.0563607 (rank : 79)	NC score	0.094883 (rank : 84)
Query Neighborhood Hits	364	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NIPBL_HUMAN
θ value	0.0563607 (rank : 80)	NC score	0.188484 (rank : 38)
Query Neighborhood Hits	364	Target Neighborhood Hits	1311	Shared Neighborhood Hits	214
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TXND2_MOUSE
θ value	0.0563607 (rank : 81)	NC score	0.161377 (rank : 41)
Query Neighborhood Hits	364	Target Neighborhood Hits	828	Shared Neighborhood Hits	168
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BRD4_MOUSE
θ value	0.0736092 (rank : 82)	NC score	0.065427 (rank : 159)
Query Neighborhood Hits	364	Target Neighborhood Hits	845	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RIF1_MOUSE
θ value	0.0736092 (rank : 83)	NC score	0.061962 (rank : 187)
Query Neighborhood Hits	364	Target Neighborhood Hits	315	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

TCOF_MOUSE
θ value	0.0736092 (rank : 84)	NC score	0.073104 (rank : 131)
Query Neighborhood Hits	364	Target Neighborhood Hits	471	Shared Neighborhood Hits	61
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

AT2B1_HUMAN
θ value	0.0961366 (rank : 85)	NC score	0.012234 (rank : 431)
Query Neighborhood Hits	364	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P20020, Q12992, Q12993, Q13819, Q13820, Q13821, Q16504, Q93082	Gene names	ATP2B1, PMCA1
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1).

DNMT1_HUMAN
θ value	0.0961366 (rank : 86)	NC score	0.084471 (rank : 107)
Query Neighborhood Hits	364	Target Neighborhood Hits	401	Shared Neighborhood Hits	89
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

NFH_MOUSE
θ value	0.0961366 (rank : 87)	NC score	0.102935 (rank : 65)
Query Neighborhood Hits	364	Target Neighborhood Hits	2247	Shared Neighborhood Hits	219
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PAR3L_HUMAN
θ value	0.0961366 (rank : 88)	NC score	0.025149 (rank : 373)
Query Neighborhood Hits	364	Target Neighborhood Hits	297	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

PCLO_MOUSE
θ value	0.0961366 (rank : 89)	NC score	0.093845 (rank : 85)
Query Neighborhood Hits	364	Target Neighborhood Hits	2275	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TGON2_HUMAN
θ value	0.0961366 (rank : 90)	NC score	0.171630 (rank : 40)
Query Neighborhood Hits	364	Target Neighborhood Hits	1037	Shared Neighborhood Hits	170
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZBT38_HUMAN
θ value	0.0961366 (rank : 91)	NC score	-0.001834 (rank : 483)
Query Neighborhood Hits	364	Target Neighborhood Hits	885	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

BASP_HUMAN
θ value	0.125558 (rank : 92)	NC score	0.078350 (rank : 118)
Query Neighborhood Hits	364	Target Neighborhood Hits	321	Shared Neighborhood Hits	48
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BRD4_HUMAN
θ value	0.125558 (rank : 93)	NC score	0.064796 (rank : 161)
Query Neighborhood Hits	364	Target Neighborhood Hits	851	Shared Neighborhood Hits	87
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MAP1A_HUMAN
θ value	0.125558 (rank : 94)	NC score	0.119572 (rank : 51)
Query Neighborhood Hits	364	Target Neighborhood Hits	1626	Shared Neighborhood Hits	200
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NUCKS_HUMAN
θ value	0.125558 (rank : 95)	NC score	0.085468 (rank : 105)
Query Neighborhood Hits	364	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PRPC_HUMAN
θ value	0.125558 (rank : 96)	NC score	0.067421 (rank : 148)
Query Neighborhood Hits	364	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

RBP1_MOUSE
θ value	0.125558 (rank : 97)	NC score	0.036903 (rank : 322)
Query Neighborhood Hits	364	Target Neighborhood Hits	493	Shared Neighborhood Hits	46
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SLK_MOUSE
θ value	0.125558 (rank : 98)	NC score	0.019997 (rank : 400)
Query Neighborhood Hits	364	Target Neighborhood Hits	1798	Shared Neighborhood Hits	136
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TITIN_HUMAN
θ value	0.125558 (rank : 99)	NC score	0.020629 (rank : 397)
Query Neighborhood Hits	364	Target Neighborhood Hits	2923	Shared Neighborhood Hits	161
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CD2L2_HUMAN
θ value	0.163984 (rank : 100)	NC score	0.013471 (rank : 424)
Query Neighborhood Hits	364	Target Neighborhood Hits	1439	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

NCOR1_MOUSE
θ value	0.163984 (rank : 101)	NC score	0.064173 (rank : 169)
Query Neighborhood Hits	364	Target Neighborhood Hits	521	Shared Neighborhood Hits	76
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

SMC3_HUMAN
θ value	0.163984 (rank : 102)	NC score	0.054429 (rank : 239)
Query Neighborhood Hits	364	Target Neighborhood Hits	1186	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.163984 (rank : 103)	NC score	0.054451 (rank : 238)
Query Neighborhood Hits	364	Target Neighborhood Hits	1187	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

BASP_MOUSE
θ value	0.21417 (rank : 104)	NC score	0.078836 (rank : 117)
Query Neighborhood Hits	364	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DAXX_MOUSE
θ value	0.21417 (rank : 105)	NC score	0.042222 (rank : 300)
Query Neighborhood Hits	364	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

NOLC1_HUMAN
θ value	0.21417 (rank : 106)	NC score	0.089335 (rank : 98)
Query Neighborhood Hits	364	Target Neighborhood Hits	452	Shared Neighborhood Hits	63
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SRCH_HUMAN
θ value	0.21417 (rank : 107)	NC score	0.066812 (rank : 153)
Query Neighborhood Hits	364	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

STK10_MOUSE
θ value	0.21417 (rank : 108)	NC score	0.040334 (rank : 306)
Query Neighborhood Hits	364	Target Neighborhood Hits	2132	Shared Neighborhood Hits	187
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TOP3A_MOUSE
θ value	0.21417 (rank : 109)	NC score	0.049193 (rank : 277)
Query Neighborhood Hits	364	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

CCD96_MOUSE
θ value	0.279714 (rank : 110)	NC score	0.059570 (rank : 202)
Query Neighborhood Hits	364	Target Neighborhood Hits	704	Shared Neighborhood Hits	108
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ELOA3_HUMAN
θ value	0.279714 (rank : 111)	NC score	0.033569 (rank : 339)
Query Neighborhood Hits	364	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

MLL2_HUMAN
θ value	0.279714 (rank : 112)	NC score	0.074834 (rank : 128)
Query Neighborhood Hits	364	Target Neighborhood Hits	1788	Shared Neighborhood Hits	130
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NCOR1_HUMAN
θ value	0.279714 (rank : 113)	NC score	0.064267 (rank : 168)
Query Neighborhood Hits	364	Target Neighborhood Hits	577	Shared Neighborhood Hits	81
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NEC1_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.013631 (rank : 421)
Query Neighborhood Hits	364	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

PRRT3_HUMAN
θ value	0.279714 (rank : 115)	NC score	0.071798 (rank : 133)
Query Neighborhood Hits	364	Target Neighborhood Hits	998	Shared Neighborhood Hits	76
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SETB1_MOUSE
θ value	0.279714 (rank : 116)	NC score	0.027323 (rank : 364)
Query Neighborhood Hits	364	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

ZN318_MOUSE
θ value	0.279714 (rank : 117)	NC score	0.103950 (rank : 64)
Query Neighborhood Hits	364	Target Neighborhood Hits	642	Shared Neighborhood Hits	114
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AP3B1_MOUSE
θ value	0.365318 (rank : 118)	NC score	0.041551 (rank : 303)
Query Neighborhood Hits	364	Target Neighborhood Hits	302	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

ATN1_HUMAN
θ value	0.365318 (rank : 119)	NC score	0.054664 (rank : 235)
Query Neighborhood Hits	364	Target Neighborhood Hits	676	Shared Neighborhood Hits	60
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CDYL2_HUMAN
θ value	0.365318 (rank : 120)	NC score	0.037760 (rank : 317)
Query Neighborhood Hits	364	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

ICAL_HUMAN
θ value	0.365318 (rank : 121)	NC score	0.098919 (rank : 71)
Query Neighborhood Hits	364	Target Neighborhood Hits	275	Shared Neighborhood Hits	90
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

IF4B_MOUSE
θ value	0.365318 (rank : 122)	NC score	0.047272 (rank : 284)
Query Neighborhood Hits	364	Target Neighborhood Hits	368	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

LRP3_HUMAN
θ value	0.365318 (rank : 123)	NC score	0.011499 (rank : 436)
Query Neighborhood Hits	364	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MINK1_HUMAN
θ value	0.365318 (rank : 124)	NC score	0.012208 (rank : 432)
Query Neighborhood Hits	364	Target Neighborhood Hits	1477	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

PRG4_MOUSE
θ value	0.365318 (rank : 125)	NC score	0.052610 (rank : 258)
Query Neighborhood Hits	364	Target Neighborhood Hits	624	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP4B_MOUSE
θ value	0.365318 (rank : 126)	NC score	0.021789 (rank : 391)
Query Neighborhood Hits	364	Target Neighborhood Hits	1040	Shared Neighborhood Hits	66
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SRRM1_MOUSE
θ value	0.365318 (rank : 127)	NC score	0.096683 (rank : 78)
Query Neighborhood Hits	364	Target Neighborhood Hits	966	Shared Neighborhood Hits	117
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ST18_HUMAN
θ value	0.365318 (rank : 128)	NC score	0.027472 (rank : 363)
Query Neighborhood Hits	364	Target Neighborhood Hits	252	Shared Neighborhood Hits	26
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

THOC2_HUMAN
θ value	0.365318 (rank : 129)	NC score	0.082905 (rank : 112)
Query Neighborhood Hits	364	Target Neighborhood Hits	337	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

CIR_HUMAN
θ value	0.47712 (rank : 130)	NC score	0.059406 (rank : 206)
Query Neighborhood Hits	364	Target Neighborhood Hits	249	Shared Neighborhood Hits	36
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CN102_HUMAN
θ value	0.47712 (rank : 131)	NC score	0.032940 (rank : 341)
Query Neighborhood Hits	364	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

DDX23_HUMAN
θ value	0.47712 (rank : 132)	NC score	0.044361 (rank : 293)
Query Neighborhood Hits	364	Target Neighborhood Hits	486	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DREB_MOUSE
θ value	0.47712 (rank : 133)	NC score	0.043482 (rank : 296)
Query Neighborhood Hits	364	Target Neighborhood Hits	446	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GOGB1_HUMAN
θ value	0.47712 (rank : 134)	NC score	0.052414 (rank : 259)
Query Neighborhood Hits	364	Target Neighborhood Hits	2297	Shared Neighborhood Hits	183
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

M3K14_MOUSE
θ value	0.47712 (rank : 135)	NC score	0.006742 (rank : 461)
Query Neighborhood Hits	364	Target Neighborhood Hits	889	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

NEK4_HUMAN
θ value	0.47712 (rank : 136)	NC score	0.003649 (rank : 476)
Query Neighborhood Hits	364	Target Neighborhood Hits	883	Shared Neighborhood Hits	24
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

PPR3A_HUMAN
θ value	0.47712 (rank : 137)	NC score	0.033355 (rank : 340)
Query Neighborhood Hits	364	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

SPRL1_MOUSE
θ value	0.47712 (rank : 138)	NC score	0.065297 (rank : 160)
Query Neighborhood Hits	364	Target Neighborhood Hits	403	Shared Neighborhood Hits	82
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TOP3A_HUMAN
θ value	0.47712 (rank : 139)	NC score	0.050721 (rank : 269)
Query Neighborhood Hits	364	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

U2AFM_MOUSE
θ value	0.47712 (rank : 140)	NC score	0.028303 (rank : 356)
Query Neighborhood Hits	364	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

UBP8_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.046008 (rank : 289)
Query Neighborhood Hits	364	Target Neighborhood Hits	751	Shared Neighborhood Hits	114
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ANR11_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.061842 (rank : 188)
Query Neighborhood Hits	364	Target Neighborhood Hits	1289	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CNKR1_HUMAN
θ value	0.62314 (rank : 143)	NC score	0.026444 (rank : 369)
Query Neighborhood Hits	364	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNTN1_MOUSE
θ value	0.62314 (rank : 144)	NC score	0.004601 (rank : 472)
Query Neighborhood Hits	364	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

DDX21_MOUSE
θ value	0.62314 (rank : 145)	NC score	0.021787 (rank : 392)
Query Neighborhood Hits	364	Target Neighborhood Hits	350	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

NOP14_HUMAN
θ value	0.62314 (rank : 146)	NC score	0.091936 (rank : 91)
Query Neighborhood Hits	364	Target Neighborhood Hits	573	Shared Neighborhood Hits	119
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

RPGR1_MOUSE
θ value	0.62314 (rank : 147)	NC score	0.041602 (rank : 302)
Query Neighborhood Hits	364	Target Neighborhood Hits	713	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

T2FA_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.064502 (rank : 165)
Query Neighborhood Hits	364	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

ZN638_MOUSE
θ value	0.62314 (rank : 149)	NC score	0.053599 (rank : 248)
Query Neighborhood Hits	364	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

AP3B2_MOUSE
θ value	0.813845 (rank : 150)	NC score	0.036610 (rank : 325)
Query Neighborhood Hits	364	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

AP3D1_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.039800 (rank : 308)
Query Neighborhood Hits	364	Target Neighborhood Hits	254	Shared Neighborhood Hits	44
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

CCP2_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.019456 (rank : 403)
Query Neighborhood Hits	364	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHG2	Gene names	Dscr1l1
Domain Architecture
Description	Calcipressin-2 (Down syndrome candidate region 1-like protein 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2).

DREB_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.040840 (rank : 304)
Query Neighborhood Hits	364	Target Neighborhood Hits	450	Shared Neighborhood Hits	45
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

EZRI_MOUSE
θ value	0.813845 (rank : 154)	NC score	0.024732 (rank : 377)
Query Neighborhood Hits	364	Target Neighborhood Hits	693	Shared Neighborhood Hits	62
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

HDAC5_MOUSE
θ value	0.813845 (rank : 155)	NC score	0.016298 (rank : 411)
Query Neighborhood Hits	364	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

JHD2C_HUMAN
θ value	0.813845 (rank : 156)	NC score	0.042896 (rank : 298)
Query Neighborhood Hits	364	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

M4K4_HUMAN
θ value	0.813845 (rank : 157)	NC score	0.012794 (rank : 427)
Query Neighborhood Hits	364	Target Neighborhood Hits	1589	Shared Neighborhood Hits	85
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	0.813845 (rank : 158)	NC score	0.013839 (rank : 419)
Query Neighborhood Hits	364	Target Neighborhood Hits	1560	Shared Neighborhood Hits	92
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NSD1_MOUSE
θ value	0.813845 (rank : 159)	NC score	0.076069 (rank : 122)
Query Neighborhood Hits	364	Target Neighborhood Hits	472	Shared Neighborhood Hits	58
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RADI_HUMAN
θ value	0.813845 (rank : 160)	NC score	0.028250 (rank : 358)
Query Neighborhood Hits	364	Target Neighborhood Hits	741	Shared Neighborhood Hits	53
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RRS1_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.037838 (rank : 316)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

SYN1_MOUSE
θ value	0.813845 (rank : 162)	NC score	0.031729 (rank : 348)
Query Neighborhood Hits	364	Target Neighborhood Hits	363	Shared Neighborhood Hits	32
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

UBP8_MOUSE
θ value	0.813845 (rank : 163)	NC score	0.024757 (rank : 376)
Query Neighborhood Hits	364	Target Neighborhood Hits	362	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

XE7_HUMAN
θ value	0.813845 (rank : 164)	NC score	0.037914 (rank : 315)
Query Neighborhood Hits	364	Target Neighborhood Hits	738	Shared Neighborhood Hits	63
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

YTDC1_HUMAN
θ value	0.813845 (rank : 165)	NC score	0.102437 (rank : 66)
Query Neighborhood Hits	364	Target Neighborhood Hits	458	Shared Neighborhood Hits	95
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ACK1_MOUSE
θ value	1.06291 (rank : 166)	NC score	0.004315 (rank : 473)
Query Neighborhood Hits	364	Target Neighborhood Hits	1080	Shared Neighborhood Hits	47
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ANKY2_HUMAN
θ value	1.06291 (rank : 167)	NC score	0.008683 (rank : 452)
Query Neighborhood Hits	364	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

CAF1A_HUMAN
θ value	1.06291 (rank : 168)	NC score	0.050239 (rank : 274)
Query Neighborhood Hits	364	Target Neighborhood Hits	750	Shared Neighborhood Hits	69
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

EFHC2_HUMAN
θ value	1.06291 (rank : 169)	NC score	0.023096 (rank : 386)
Query Neighborhood Hits	364	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

ICAL_MOUSE
θ value	1.06291 (rank : 170)	NC score	0.058079 (rank : 216)
Query Neighborhood Hits	364	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

INVO_HUMAN
θ value	1.06291 (rank : 171)	NC score	0.033633 (rank : 338)
Query Neighborhood Hits	364	Target Neighborhood Hits	636	Shared Neighborhood Hits	55
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	1.06291 (rank : 172)	NC score	0.056584 (rank : 223)
Query Neighborhood Hits	364	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

KI21A_MOUSE
θ value	1.06291 (rank : 173)	NC score	0.029138 (rank : 355)
Query Neighborhood Hits	364	Target Neighborhood Hits	1317	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MINK1_MOUSE
θ value	1.06291 (rank : 174)	NC score	0.011182 (rank : 439)
Query Neighborhood Hits	364	Target Neighborhood Hits	1451	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NCOR2_MOUSE
θ value	1.06291 (rank : 175)	NC score	0.063357 (rank : 177)
Query Neighborhood Hits	364	Target Neighborhood Hits	790	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PRP4B_HUMAN
θ value	1.06291 (rank : 176)	NC score	0.019416 (rank : 404)
Query Neighborhood Hits	364	Target Neighborhood Hits	1030	Shared Neighborhood Hits	64
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

AFF1_HUMAN
θ value	1.38821 (rank : 177)	NC score	0.059083 (rank : 208)
Query Neighborhood Hits	364	Target Neighborhood Hits	506	Shared Neighborhood Hits	68
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

APEX2_HUMAN
θ value	1.38821 (rank : 178)	NC score	0.047759 (rank : 283)
Query Neighborhood Hits	364	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

APEX2_MOUSE
θ value	1.38821 (rank : 179)	NC score	0.046207 (rank : 288)
Query Neighborhood Hits	364	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

CEBPZ_MOUSE
θ value	1.38821 (rank : 180)	NC score	0.019920 (rank : 401)
Query Neighborhood Hits	364	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P53569, Q3TXW5, Q3TYA8, Q3UWQ7	Gene names	Cebpz, Cbf2, Cebpa-rs1
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

CENPE_HUMAN
θ value	1.38821 (rank : 181)	NC score	0.043284 (rank : 297)
Query Neighborhood Hits	364	Target Neighborhood Hits	2060	Shared Neighborhood Hits	170
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

COIA1_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.012579 (rank : 428)
Query Neighborhood Hits	364	Target Neighborhood Hits	481	Shared Neighborhood Hits	30
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CSF1_HUMAN
θ value	1.38821 (rank : 183)	NC score	0.036559 (rank : 327)
Query Neighborhood Hits	364	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CYLC2_HUMAN
θ value	1.38821 (rank : 184)	NC score	0.085903 (rank : 104)
Query Neighborhood Hits	364	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

FA50A_HUMAN
θ value	1.38821 (rank : 185)	NC score	0.024807 (rank : 375)
Query Neighborhood Hits	364	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

GPTC8_HUMAN
θ value	1.38821 (rank : 186)	NC score	0.071441 (rank : 134)
Query Neighborhood Hits	364	Target Neighborhood Hits	366	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

INCE_HUMAN
θ value	1.38821 (rank : 187)	NC score	0.036889 (rank : 323)
Query Neighborhood Hits	364	Target Neighborhood Hits	978	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LAP4_MOUSE
θ value	1.38821 (rank : 188)	NC score	0.006860 (rank : 460)
Query Neighborhood Hits	364	Target Neighborhood Hits	590	Shared Neighborhood Hits	30
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NCOR2_HUMAN
θ value	1.38821 (rank : 189)	NC score	0.064084 (rank : 172)
Query Neighborhood Hits	364	Target Neighborhood Hits	870	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PRR12_HUMAN
θ value	1.38821 (rank : 190)	NC score	0.045142 (rank : 291)
Query Neighborhood Hits	364	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RBBP6_HUMAN
θ value	1.38821 (rank : 191)	NC score	0.153705 (rank : 43)
Query Neighborhood Hits	364	Target Neighborhood Hits	1135	Shared Neighborhood Hits	181
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	1.38821 (rank : 192)	NC score	0.149866 (rank : 45)
Query Neighborhood Hits	364	Target Neighborhood Hits	1014	Shared Neighborhood Hits	167
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REN3B_HUMAN
θ value	1.38821 (rank : 193)	NC score	0.048754 (rank : 278)
Query Neighborhood Hits	364	Target Neighborhood Hits	412	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RIMS1_HUMAN
θ value	1.38821 (rank : 194)	NC score	0.035407 (rank : 333)
Query Neighborhood Hits	364	Target Neighborhood Hits	437	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RRBP1_MOUSE
θ value	1.38821 (rank : 195)	NC score	0.088717 (rank : 100)
Query Neighborhood Hits	364	Target Neighborhood Hits	1650	Shared Neighborhood Hits	197
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RRS1_MOUSE
θ value	1.38821 (rank : 196)	NC score	0.035736 (rank : 330)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

SFRS8_HUMAN
θ value	1.38821 (rank : 197)	NC score	0.043527 (rank : 295)
Query Neighborhood Hits	364	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SMRC1_MOUSE
θ value	1.38821 (rank : 198)	NC score	0.036450 (rank : 328)
Query Neighborhood Hits	364	Target Neighborhood Hits	459	Shared Neighborhood Hits	68
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SRRM1_HUMAN
θ value	1.38821 (rank : 199)	NC score	0.080703 (rank : 115)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TARA_MOUSE
θ value	1.38821 (rank : 200)	NC score	0.064285 (rank : 167)
Query Neighborhood Hits	364	Target Neighborhood Hits	1133	Shared Neighborhood Hits	127
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TR150_MOUSE
θ value	1.38821 (rank : 201)	NC score	0.112207 (rank : 56)
Query Neighborhood Hits	364	Target Neighborhood Hits	468	Shared Neighborhood Hits	135
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

WDR60_HUMAN
θ value	1.38821 (rank : 202)	NC score	0.036793 (rank : 324)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

CENPF_HUMAN
θ value	1.81305 (rank : 203)	NC score	0.035060 (rank : 334)
Query Neighborhood Hits	364	Target Neighborhood Hits	1932	Shared Neighborhood Hits	160
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HS90A_MOUSE
θ value	1.81305 (rank : 204)	NC score	0.014779 (rank : 415)
Query Neighborhood Hits	364	Target Neighborhood Hits	155	Shared Neighborhood Hits	23
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

LAD1_HUMAN
θ value	1.81305 (rank : 205)	NC score	0.092271 (rank : 90)
Query Neighborhood Hits	364	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LARP1_HUMAN
θ value	1.81305 (rank : 206)	NC score	0.055952 (rank : 227)
Query Neighborhood Hits	364	Target Neighborhood Hits	242	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

LYAR_MOUSE
θ value	1.81305 (rank : 207)	NC score	0.043655 (rank : 294)
Query Neighborhood Hits	364	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

PALB2_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.023473 (rank : 383)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PDZK4_MOUSE
θ value	1.81305 (rank : 209)	NC score	0.016690 (rank : 409)
Query Neighborhood Hits	364	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

PER3_HUMAN
θ value	1.81305 (rank : 210)	NC score	0.025561 (rank : 371)
Query Neighborhood Hits	364	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PKCB1_HUMAN
θ value	1.81305 (rank : 211)	NC score	0.105898 (rank : 62)
Query Neighborhood Hits	364	Target Neighborhood Hits	488	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RADI_MOUSE
θ value	1.81305 (rank : 212)	NC score	0.027642 (rank : 361)
Query Neighborhood Hits	364	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RERE_MOUSE
θ value	1.81305 (rank : 213)	NC score	0.036582 (rank : 326)
Query Neighborhood Hits	364	Target Neighborhood Hits	785	Shared Neighborhood Hits	62
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SET1A_HUMAN
θ value	1.81305 (rank : 214)	NC score	0.058716 (rank : 213)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	74
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SFR16_MOUSE
θ value	1.81305 (rank : 215)	NC score	0.038542 (rank : 313)
Query Neighborhood Hits	364	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

ZC313_HUMAN
θ value	1.81305 (rank : 216)	NC score	0.092844 (rank : 87)
Query Neighborhood Hits	364	Target Neighborhood Hits	772	Shared Neighborhood Hits	131
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZSCA1_HUMAN
θ value	1.81305 (rank : 217)	NC score	-0.002825 (rank : 484)
Query Neighborhood Hits	364	Target Neighborhood Hits	724	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

AKA12_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.123595 (rank : 50)
Query Neighborhood Hits	364	Target Neighborhood Hits	825	Shared Neighborhood Hits	149
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DAAM1_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.014371 (rank : 417)
Query Neighborhood Hits	364	Target Neighborhood Hits	483	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

DCAK3_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.003137 (rank : 479)
Query Neighborhood Hits	364	Target Neighborhood Hits	888	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

DPOLZ_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.020992 (rank : 394)
Query Neighborhood Hits	364	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

GDF5_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.005395 (rank : 470)
Query Neighborhood Hits	364	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

INCE_MOUSE
θ value	2.36792 (rank : 223)	NC score	0.040173 (rank : 307)
Query Neighborhood Hits	364	Target Neighborhood Hits	903	Shared Neighborhood Hits	76
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IRX5_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.012359 (rank : 430)
Query Neighborhood Hits	364	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

MARCS_HUMAN
θ value	2.36792 (rank : 225)	NC score	0.040530 (rank : 305)
Query Neighborhood Hits	364	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MICA1_HUMAN
θ value	2.36792 (rank : 226)	NC score	0.020651 (rank : 396)
Query Neighborhood Hits	364	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

PEPL_MOUSE
θ value	2.36792 (rank : 227)	NC score	0.034190 (rank : 336)
Query Neighborhood Hits	364	Target Neighborhood Hits	1105	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PSIP1_HUMAN
θ value	2.36792 (rank : 228)	NC score	0.057356 (rank : 219)
Query Neighborhood Hits	364	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

SFPQ_MOUSE
θ value	2.36792 (rank : 229)	NC score	0.024027 (rank : 380)
Query Neighborhood Hits	364	Target Neighborhood Hits	958	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SIA7A_HUMAN
θ value	2.36792 (rank : 230)	NC score	0.030699 (rank : 351)
Query Neighborhood Hits	364	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

TNAP2_HUMAN
θ value	2.36792 (rank : 231)	NC score	0.015829 (rank : 414)
Query Neighborhood Hits	364	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q03169, Q86VI0	Gene names	TNFAIP2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

TTF1_MOUSE
θ value	2.36792 (rank : 232)	NC score	0.083083 (rank : 111)
Query Neighborhood Hits	364	Target Neighborhood Hits	277	Shared Neighborhood Hits	88
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ZEP1_MOUSE
θ value	2.36792 (rank : 233)	NC score	0.007340 (rank : 458)
Query Neighborhood Hits	364	Target Neighborhood Hits	1063	Shared Neighborhood Hits	50
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ACRBP_HUMAN
θ value	3.0926 (rank : 234)	NC score	0.019248 (rank : 405)
Query Neighborhood Hits	364	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

APC_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.041688 (rank : 301)
Query Neighborhood Hits	364	Target Neighborhood Hits	603	Shared Neighborhood Hits	71
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ATRIP_MOUSE
θ value	3.0926 (rank : 236)	NC score	0.020926 (rank : 395)
Query Neighborhood Hits	364	Target Neighborhood Hits	248	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

BCLF1_HUMAN
θ value	3.0926 (rank : 237)	NC score	0.059714 (rank : 200)
Query Neighborhood Hits	364	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

BLNK_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.027935 (rank : 360)
Query Neighborhood Hits	364	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

BORG4_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.014622 (rank : 416)
Query Neighborhood Hits	364	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

CCNL1_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.035035 (rank : 335)
Query Neighborhood Hits	364	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL2_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.029734 (rank : 354)
Query Neighborhood Hits	364	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

CROP_MOUSE
θ value	3.0926 (rank : 242)	NC score	0.053964 (rank : 244)
Query Neighborhood Hits	364	Target Neighborhood Hits	403	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

DDX55_MOUSE
θ value	3.0926 (rank : 243)	NC score	0.007625 (rank : 457)
Query Neighborhood Hits	364	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DNL3_HUMAN
θ value	3.0926 (rank : 244)	NC score	0.013566 (rank : 423)
Query Neighborhood Hits	364	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

IRX3_HUMAN
θ value	3.0926 (rank : 245)	NC score	0.009877 (rank : 448)
Query Neighborhood Hits	364	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

MYH11_HUMAN
θ value	3.0926 (rank : 246)	NC score	0.030492 (rank : 352)
Query Neighborhood Hits	364	Target Neighborhood Hits	1806	Shared Neighborhood Hits	164
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NFL_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.025729 (rank : 370)
Query Neighborhood Hits	364	Target Neighborhood Hits	666	Shared Neighborhood Hits	58
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

P66B_MOUSE
θ value	3.0926 (rank : 248)	NC score	0.025046 (rank : 374)
Query Neighborhood Hits	364	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

RHBD1_HUMAN
θ value	3.0926 (rank : 249)	NC score	0.011984 (rank : 434)
Query Neighborhood Hits	364	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	O75783, Q9NQ85	Gene names	RHBDL1, RHBDL
Domain Architecture
Description	Rhomboid-related protein 1 (EC 3.4.21.105) (RRP) (Rhomboid-like protein 1).

SYEP_MOUSE
θ value	3.0926 (rank : 250)	NC score	0.025294 (rank : 372)
Query Neighborhood Hits	364	Target Neighborhood Hits	123	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

TCAL6_HUMAN
θ value	3.0926 (rank : 251)	NC score	0.022590 (rank : 389)
Query Neighborhood Hits	364	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

TF3C1_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.014318 (rank : 418)
Query Neighborhood Hits	364	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TOP1_MOUSE
θ value	3.0926 (rank : 253)	NC score	0.038092 (rank : 314)
Query Neighborhood Hits	364	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ZDHC8_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.009569 (rank : 450)
Query Neighborhood Hits	364	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN206_HUMAN
θ value	3.0926 (rank : 255)	NC score	-0.005973 (rank : 486)
Query Neighborhood Hits	364	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

ARI4A_HUMAN
θ value	4.03905 (rank : 256)	NC score	0.047950 (rank : 282)
Query Neighborhood Hits	364	Target Neighborhood Hits	434	Shared Neighborhood Hits	57
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BRD3_HUMAN
θ value	4.03905 (rank : 257)	NC score	0.051659 (rank : 263)
Query Neighborhood Hits	364	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD7_MOUSE
θ value	4.03905 (rank : 258)	NC score	0.046427 (rank : 286)
Query Neighborhood Hits	364	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

CAF1A_MOUSE
θ value	4.03905 (rank : 259)	NC score	0.051384 (rank : 266)
Query Neighborhood Hits	364	Target Neighborhood Hits	736	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCNL1_MOUSE
θ value	4.03905 (rank : 260)	NC score	0.032104 (rank : 346)
Query Neighborhood Hits	364	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CS007_HUMAN
θ value	4.03905 (rank : 261)	NC score	0.037204 (rank : 321)
Query Neighborhood Hits	364	Target Neighborhood Hits	401	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CS007_MOUSE
θ value	4.03905 (rank : 262)	NC score	0.035470 (rank : 331)
Query Neighborhood Hits	364	Target Neighborhood Hits	464	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DAAM1_MOUSE
θ value	4.03905 (rank : 263)	NC score	0.016247 (rank : 412)
Query Neighborhood Hits	364	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

GP156_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.015890 (rank : 413)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GRIP2_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.010529 (rank : 444)
Query Neighborhood Hits	364	Target Neighborhood Hits	256	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

IF2P_HUMAN
θ value	4.03905 (rank : 266)	NC score	0.052058 (rank : 262)
Query Neighborhood Hits	364	Target Neighborhood Hits	889	Shared Neighborhood Hits	84
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LRRF1_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.060968 (rank : 194)
Query Neighborhood Hits	364	Target Neighborhood Hits	625	Shared Neighborhood Hits	80
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

LYST_HUMAN
θ value	4.03905 (rank : 268)	NC score	0.009650 (rank : 449)
Query Neighborhood Hits	364	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

MAP9_HUMAN
θ value	4.03905 (rank : 269)	NC score	0.047148 (rank : 285)
Query Neighborhood Hits	364	Target Neighborhood Hits	518	Shared Neighborhood Hits	71
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAP9_MOUSE
θ value	4.03905 (rank : 270)	NC score	0.054346 (rank : 241)
Query Neighborhood Hits	364	Target Neighborhood Hits	529	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NFRKB_HUMAN
θ value	4.03905 (rank : 271)	NC score	0.029979 (rank : 353)
Query Neighborhood Hits	364	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PHAR3_HUMAN
θ value	4.03905 (rank : 272)	NC score	0.037441 (rank : 319)
Query Neighborhood Hits	364	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PTN23_MOUSE
θ value	4.03905 (rank : 273)	NC score	0.010737 (rank : 441)
Query Neighborhood Hits	364	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SKIV2_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.010941 (rank : 440)
Query Neighborhood Hits	364	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

ST18_MOUSE
θ value	4.03905 (rank : 275)	NC score	0.016463 (rank : 410)
Query Neighborhood Hits	364	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

TPR_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.045304 (rank : 290)
Query Neighborhood Hits	364	Target Neighborhood Hits	1921	Shared Neighborhood Hits	159
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

VINEX_MOUSE
θ value	4.03905 (rank : 277)	NC score	0.005723 (rank : 467)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

ADDA_HUMAN
θ value	5.27518 (rank : 278)	NC score	0.011889 (rank : 435)
Query Neighborhood Hits	364	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

AKP8L_HUMAN
θ value	5.27518 (rank : 279)	NC score	0.011251 (rank : 438)
Query Neighborhood Hits	364	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

ANK3_HUMAN
θ value	5.27518 (rank : 280)	NC score	0.013591 (rank : 422)
Query Neighborhood Hits	364	Target Neighborhood Hits	853	Shared Neighborhood Hits	85
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

BRD3_MOUSE
θ value	5.27518 (rank : 281)	NC score	0.052203 (rank : 261)
Query Neighborhood Hits	364	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRE1A_HUMAN
θ value	5.27518 (rank : 282)	NC score	0.024382 (rank : 379)
Query Neighborhood Hits	364	Target Neighborhood Hits	1071	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	5.27518 (rank : 283)	NC score	0.023826 (rank : 381)
Query Neighborhood Hits	364	Target Neighborhood Hits	1025	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CABIN_HUMAN
θ value	5.27518 (rank : 284)	NC score	0.046214 (rank : 287)
Query Neighborhood Hits	364	Target Neighborhood Hits	490	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCAR1_HUMAN
θ value	5.27518 (rank : 285)	NC score	0.032058 (rank : 347)
Query Neighborhood Hits	364	Target Neighborhood Hits	444	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCD43_MOUSE
θ value	5.27518 (rank : 286)	NC score	0.023104 (rank : 385)
Query Neighborhood Hits	364	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CR29, Q6PDT2	Gene names	Ccdc43, D11Ertd707e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

CD2L1_HUMAN
θ value	5.27518 (rank : 287)	NC score	0.010668 (rank : 443)
Query Neighborhood Hits	364	Target Neighborhood Hits	1467	Shared Neighborhood Hits	84
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CKAP4_MOUSE
θ value	5.27518 (rank : 288)	NC score	0.020158 (rank : 398)
Query Neighborhood Hits	364	Target Neighborhood Hits	596	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CNTN1_HUMAN
θ value	5.27518 (rank : 289)	NC score	0.002663 (rank : 481)
Query Neighborhood Hits	364	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

DHX16_HUMAN
θ value	5.27518 (rank : 290)	NC score	0.020028 (rank : 399)
Query Neighborhood Hits	364	Target Neighborhood Hits	356	Shared Neighborhood Hits	54
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DNL1_MOUSE
θ value	5.27518 (rank : 291)	NC score	0.032196 (rank : 345)
Query Neighborhood Hits	364	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

FA50B_HUMAN
θ value	5.27518 (rank : 292)	NC score	0.019760 (rank : 402)
Query Neighborhood Hits	364	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y247	Gene names	FAM50B, X5L
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

IBP4_HUMAN
θ value	5.27518 (rank : 293)	NC score	0.006245 (rank : 462)
Query Neighborhood Hits	364	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

ITSN1_HUMAN
θ value	5.27518 (rank : 294)	NC score	0.032785 (rank : 342)
Query Neighborhood Hits	364	Target Neighborhood Hits	1757	Shared Neighborhood Hits	151
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NAF1_HUMAN
θ value	5.27518 (rank : 295)	NC score	0.045014 (rank : 292)
Query Neighborhood Hits	364	Target Neighborhood Hits	937	Shared Neighborhood Hits	108
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NGAP_HUMAN
θ value	5.27518 (rank : 296)	NC score	0.012400 (rank : 429)
Query Neighborhood Hits	364	Target Neighborhood Hits	517	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

P66B_HUMAN
θ value	5.27518 (rank : 297)	NC score	0.026537 (rank : 367)
Query Neighborhood Hits	364	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

PRG4_HUMAN
θ value	5.27518 (rank : 298)	NC score	0.055034 (rank : 233)
Query Neighborhood Hits	364	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SEP11_MOUSE
θ value	5.27518 (rank : 299)	NC score	0.005421 (rank : 469)
Query Neighborhood Hits	364	Target Neighborhood Hits	300	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

SFPQ_HUMAN
θ value	5.27518 (rank : 300)	NC score	0.027586 (rank : 362)
Query Neighborhood Hits	364	Target Neighborhood Hits	986	Shared Neighborhood Hits	74
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TMC2_HUMAN
θ value	5.27518 (rank : 301)	NC score	0.013376 (rank : 425)
Query Neighborhood Hits	364	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TNR6A_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.038700 (rank : 312)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TRDN_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.061762 (rank : 190)
Query Neighborhood Hits	364	Target Neighborhood Hits	542	Shared Neighborhood Hits	72
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TTC14_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.031201 (rank : 350)
Query Neighborhood Hits	364	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TULP1_HUMAN
θ value	5.27518 (rank : 305)	NC score	0.016908 (rank : 408)
Query Neighborhood Hits	364	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ZN291_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.021682 (rank : 393)
Query Neighborhood Hits	364	Target Neighborhood Hits	647	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

ZN434_HUMAN
θ value	5.27518 (rank : 307)	NC score	-0.006450 (rank : 488)
Query Neighborhood Hits	364	Target Neighborhood Hits	747	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NX65, Q7Z6G2	Gene names	ZNF434
Domain Architecture
Description	Zinc finger protein 434.

AFF4_HUMAN
θ value	6.88961 (rank : 308)	NC score	0.090550 (rank : 93)
Query Neighborhood Hits	364	Target Neighborhood Hits	611	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AKAP1_MOUSE
θ value	6.88961 (rank : 309)	NC score	0.024708 (rank : 378)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

AZI1_MOUSE
θ value	6.88961 (rank : 310)	NC score	0.027940 (rank : 359)
Query Neighborhood Hits	364	Target Neighborhood Hits	990	Shared Neighborhood Hits	102
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CAC1E_HUMAN
θ value	6.88961 (rank : 311)	NC score	0.006198 (rank : 463)
Query Neighborhood Hits	364	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	6.88961 (rank : 312)	NC score	0.005833 (rank : 466)
Query Neighborhood Hits	364	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CCD19_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.026713 (rank : 366)
Query Neighborhood Hits	364	Target Neighborhood Hits	639	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD43_HUMAN
θ value	6.88961 (rank : 314)	NC score	0.023345 (rank : 384)
Query Neighborhood Hits	364	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

CD2L1_MOUSE
θ value	6.88961 (rank : 315)	NC score	0.011490 (rank : 437)
Query Neighborhood Hits	364	Target Neighborhood Hits	1463	Shared Neighborhood Hits	86
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CJ012_HUMAN
θ value	6.88961 (rank : 316)	NC score	0.095181 (rank : 83)
Query Neighborhood Hits	364	Target Neighborhood Hits	467	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CN102_MOUSE
θ value	6.88961 (rank : 317)	NC score	0.023525 (rank : 382)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

CNGA1_HUMAN
θ value	6.88961 (rank : 318)	NC score	0.007650 (rank : 456)
Query Neighborhood Hits	364	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CROP_HUMAN
θ value	6.88961 (rank : 319)	NC score	0.048586 (rank : 279)
Query Neighborhood Hits	364	Target Neighborhood Hits	402	Shared Neighborhood Hits	51
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CUTL1_MOUSE
θ value	6.88961 (rank : 320)	NC score	0.038859 (rank : 310)
Query Neighborhood Hits	364	Target Neighborhood Hits	1620	Shared Neighborhood Hits	141
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DNJC1_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.008817 (rank : 451)
Query Neighborhood Hits	364	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

EZRI_HUMAN
θ value	6.88961 (rank : 322)	NC score	0.026523 (rank : 368)
Query Neighborhood Hits	364	Target Neighborhood Hits	663	Shared Neighborhood Hits	60
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

GAGB1_HUMAN
θ value	6.88961 (rank : 323)	NC score	0.022472 (rank : 390)
Query Neighborhood Hits	364	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	O75459, Q6FGM3, Q9BSS7	Gene names	PAGE1, GAGE9, GAGEB1
Domain Architecture
Description	G antigen family B member 1 (Prostate-associated gene 1 protein) (PAGE-1) (GAGE-9) (AL5).

LAD1_MOUSE
θ value	6.88961 (rank : 324)	NC score	0.111641 (rank : 57)
Query Neighborhood Hits	364	Target Neighborhood Hits	391	Shared Neighborhood Hits	104
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MERL_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.022685 (rank : 388)
Query Neighborhood Hits	364	Target Neighborhood Hits	532	Shared Neighborhood Hits	55
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	6.88961 (rank : 326)	NC score	0.022724 (rank : 387)
Query Neighborhood Hits	364	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MILK1_HUMAN
θ value	6.88961 (rank : 327)	NC score	0.037682 (rank : 318)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NACAM_MOUSE
θ value	6.88961 (rank : 328)	NC score	0.073244 (rank : 130)
Query Neighborhood Hits	364	Target Neighborhood Hits	1866	Shared Neighborhood Hits	139
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PHAR3_MOUSE
θ value	6.88961 (rank : 329)	NC score	0.034032 (rank : 337)
Query Neighborhood Hits	364	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PKHA4_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.010421 (rank : 445)
Query Neighborhood Hits	364	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

SAKS1_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.013282 (rank : 426)
Query Neighborhood Hits	364	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SELS_MOUSE
θ value	6.88961 (rank : 332)	NC score	0.013650 (rank : 420)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

STML1_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.008056 (rank : 454)
Query Neighborhood Hits	364	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

UBP35_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.010275 (rank : 446)
Query Neighborhood Hits	364	Target Neighborhood Hits	223	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

ACINU_HUMAN
θ value	8.99809 (rank : 335)	NC score	0.092741 (rank : 88)
Query Neighborhood Hits	364	Target Neighborhood Hits	828	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACK1_HUMAN
θ value	8.99809 (rank : 336)	NC score	0.003649 (rank : 475)
Query Neighborhood Hits	364	Target Neighborhood Hits	1140	Shared Neighborhood Hits	57
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ARHGC_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.006063 (rank : 465)
Query Neighborhood Hits	364	Target Neighborhood Hits	344	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CI082_MOUSE
θ value	8.99809 (rank : 338)	NC score	0.010731 (rank : 442)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

CIP4_HUMAN
θ value	8.99809 (rank : 339)	NC score	0.018012 (rank : 406)
Query Neighborhood Hits	364	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CIR_MOUSE
θ value	8.99809 (rank : 340)	NC score	0.062181 (rank : 185)
Query Neighborhood Hits	364	Target Neighborhood Hits	255	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CNGA1_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.010214 (rank : 447)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CTR9_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.038730 (rank : 311)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	53
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

ITPR1_HUMAN
θ value	8.99809 (rank : 343)	NC score	0.004169 (rank : 474)
Query Neighborhood Hits	364	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITSN1_MOUSE
θ value	8.99809 (rank : 344)	NC score	0.032580 (rank : 343)
Query Neighborhood Hits	364	Target Neighborhood Hits	1669	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KI21A_HUMAN
θ value	8.99809 (rank : 345)	NC score	0.036252 (rank : 329)
Query Neighborhood Hits	364	Target Neighborhood Hits	1543	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LAP2_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.003457 (rank : 478)
Query Neighborhood Hits	364	Target Neighborhood Hits	499	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_MOUSE
θ value	8.99809 (rank : 347)	NC score	0.003648 (rank : 477)
Query Neighborhood Hits	364	Target Neighborhood Hits	482	Shared Neighborhood Hits	20
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

MBTP1_HUMAN
θ value	8.99809 (rank : 348)	NC score	0.007996 (rank : 455)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MYPT1_MOUSE
θ value	8.99809 (rank : 349)	NC score	0.005592 (rank : 468)
Query Neighborhood Hits	364	Target Neighborhood Hits	539	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

NEB1_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.032274 (rank : 344)
Query Neighborhood Hits	364	Target Neighborhood Hits	829	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NEK3_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.000855 (rank : 482)
Query Neighborhood Hits	364	Target Neighborhood Hits	854	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

OS9_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.028291 (rank : 357)
Query Neighborhood Hits	364	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PELP1_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.048437 (rank : 280)
Query Neighborhood Hits	364	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PKDRE_MOUSE
θ value	8.99809 (rank : 354)	NC score	0.004977 (rank : 471)
Query Neighborhood Hits	364	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PRD10_HUMAN
θ value	8.99809 (rank : 355)	NC score	-0.006417 (rank : 487)
Query Neighborhood Hits	364	Target Neighborhood Hits	769	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

RBM19_MOUSE
θ value	8.99809 (rank : 356)	NC score	0.006113 (rank : 464)
Query Neighborhood Hits	364	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RD23A_MOUSE
θ value	8.99809 (rank : 357)	NC score	0.008420 (rank : 453)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

SLK_HUMAN
θ value	8.99809 (rank : 358)	NC score	0.017704 (rank : 407)
Query Neighborhood Hits	364	Target Neighborhood Hits	1775	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SMRC1_HUMAN
θ value	8.99809 (rank : 359)	NC score	0.031288 (rank : 349)
Query Neighborhood Hits	364	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SYP2L_MOUSE
θ value	8.99809 (rank : 360)	NC score	0.012208 (rank : 433)
Query Neighborhood Hits	364	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAB1_MOUSE
θ value	8.99809 (rank : 361)	NC score	0.007113 (rank : 459)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CF89, Q7TQJ5, Q80V65, Q8R0D1	Gene names	Map3k7ip1, Tab1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

TNC6B_HUMAN
θ value	8.99809 (rank : 362)	NC score	0.027165 (rank : 365)
Query Neighborhood Hits	364	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TRPC2_MOUSE
θ value	8.99809 (rank : 363)	NC score	0.002673 (rank : 480)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

ZBTB9_MOUSE
θ value	8.99809 (rank : 364)	NC score	-0.003638 (rank : 485)
Query Neighborhood Hits	364	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ACINU_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.053470 (rank : 250)
Query Neighborhood Hits	364	Target Neighborhood Hits	712	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADDB_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.079525 (rank : 116)
Query Neighborhood Hits	364	Target Neighborhood Hits	574	Shared Neighborhood Hits	137
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AFF4_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.083156 (rank : 110)
Query Neighborhood Hits	364	Target Neighborhood Hits	581	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AIRE_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.071073 (rank : 136)
Query Neighborhood Hits	364	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.072780 (rank : 132)
Query Neighborhood Hits	364	Target Neighborhood Hits	196	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ALO17_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.066306 (rank : 156)
Query Neighborhood Hits	364	Target Neighborhood Hits	317	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ARI5B_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.074477 (rank : 129)
Query Neighborhood Hits	364	Target Neighborhood Hits	328	Shared Neighborhood Hits	107
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.074840 (rank : 127)
Query Neighborhood Hits	364	Target Neighborhood Hits	693	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.088806 (rank : 99)
Query Neighborhood Hits	364	Target Neighborhood Hits	701	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.069810 (rank : 139)
Query Neighborhood Hits	364	Target Neighborhood Hits	394	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.054231 (rank : 243)
Query Neighborhood Hits	364	Target Neighborhood Hits	780	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.058309 (rank : 215)
Query Neighborhood Hits	364	Target Neighborhood Hits	744	Shared Neighborhood Hits	82
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.059044 (rank : 209)
Query Neighborhood Hits	364	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.097822 (rank : 75)
Query Neighborhood Hits	364	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRCA1_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.051650 (rank : 264)
Query Neighborhood Hits	364	Target Neighborhood Hits	436	Shared Neighborhood Hits	52
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRD8_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.050530 (rank : 271)
Query Neighborhood Hits	364	Target Neighborhood Hits	422	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

C8AP2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.078223 (rank : 119)
Query Neighborhood Hits	364	Target Neighborhood Hits	548	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.052720 (rank : 255)
Query Neighborhood Hits	364	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.052720 (rank : 256)
Query Neighborhood Hits	364	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.067289 (rank : 151)
Query Neighborhood Hits	364	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.059432 (rank : 205)
Query Neighborhood Hits	364	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CCD21_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.052911 (rank : 254)
Query Neighborhood Hits	364	Target Neighborhood Hits	1228	Shared Neighborhood Hits	138
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.053020 (rank : 253)
Query Neighborhood Hits	364	Target Neighborhood Hits	1135	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD55_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.089532 (rank : 96)
Query Neighborhood Hits	364	Target Neighborhood Hits	513	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD55_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.091277 (rank : 92)
Query Neighborhood Hits	364	Target Neighborhood Hits	519	Shared Neighborhood Hits	116
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD91_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.059856 (rank : 199)
Query Neighborhood Hits	364	Target Neighborhood Hits	868	Shared Neighborhood Hits	121
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CEP35_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.055230 (rank : 230)
Query Neighborhood Hits	364	Target Neighborhood Hits	811	Shared Neighborhood Hits	121
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CF010_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.096244 (rank : 80)
Query Neighborhood Hits	364	Target Neighborhood Hits	329	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CI039_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.054743 (rank : 234)
Query Neighborhood Hits	364	Target Neighborhood Hits	1171	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CJ078_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.066166 (rank : 157)
Query Neighborhood Hits	364	Target Neighborhood Hits	559	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CT2NL_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.062666 (rank : 183)
Query Neighborhood Hits	364	Target Neighborhood Hits	1059	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.053062 (rank : 252)
Query Neighborhood Hits	364	Target Neighborhood Hits	902	Shared Neighborhood Hits	130
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DIDO1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.050043 (rank : 276)
Query Neighborhood Hits	364	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DMN_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.054256 (rank : 242)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	132
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DMP1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.067437 (rank : 147)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.076473 (rank : 121)
Query Neighborhood Hits	364	Target Neighborhood Hits	498	Shared Neighborhood Hits	73
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.058965 (rank : 212)
Query Neighborhood Hits	364	Target Neighborhood Hits	645	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.059968 (rank : 198)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ELOA1_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.090206 (rank : 95)
Query Neighborhood Hits	364	Target Neighborhood Hits	388	Shared Neighborhood Hits	105
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ERIC1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.053951 (rank : 245)
Query Neighborhood Hits	364	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

ESCO1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.061967 (rank : 186)
Query Neighborhood Hits	364	Target Neighborhood Hits	361	Shared Neighborhood Hits	77
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

FILA_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.064543 (rank : 163)
Query Neighborhood Hits	364	Target Neighborhood Hits	685	Shared Neighborhood Hits	76
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GRIN1_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.059007 (rank : 211)
Query Neighborhood Hits	364	Target Neighborhood Hits	681	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HIRP3_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.075693 (rank : 124)
Query Neighborhood Hits	364	Target Neighborhood Hits	323	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HRX_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.067238 (rank : 152)
Query Neighborhood Hits	364	Target Neighborhood Hits	825	Shared Neighborhood Hits	95
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

IWS1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.153507 (rank : 44)
Query Neighborhood Hits	364	Target Neighborhood Hits	1241	Shared Neighborhood Hits	188
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.156979 (rank : 42)
Query Neighborhood Hits	364	Target Neighborhood Hits	1258	Shared Neighborhood Hits	199
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KI67_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.100387 (rank : 69)
Query Neighborhood Hits	364	Target Neighborhood Hits	581	Shared Neighborhood Hits	117
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LEO1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.135560 (rank : 46)
Query Neighborhood Hits	364	Target Neighborhood Hits	958	Shared Neighborhood Hits	160
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.131336 (rank : 47)
Query Neighborhood Hits	364	Target Neighborhood Hits	946	Shared Neighborhood Hits	160
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.053521 (rank : 249)
Query Neighborhood Hits	364	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MATR3_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.055184 (rank : 231)
Query Neighborhood Hits	364	Target Neighborhood Hits	325	Shared Neighborhood Hits	86
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.060128 (rank : 197)
Query Neighborhood Hits	364	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MDC1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.104112 (rank : 63)
Query Neighborhood Hits	364	Target Neighborhood Hits	1446	Shared Neighborhood Hits	188
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINT_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.075016 (rank : 126)
Query Neighborhood Hits	364	Target Neighborhood Hits	1291	Shared Neighborhood Hits	163
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MINT_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.086935 (rank : 102)
Query Neighborhood Hits	364	Target Neighborhood Hits	1514	Shared Neighborhood Hits	185
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL3_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.075634 (rank : 125)
Query Neighborhood Hits	364	Target Neighborhood Hits	1644	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.069529 (rank : 141)
Query Neighborhood Hits	364	Target Neighborhood Hits	1399	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MPP8_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.090487 (rank : 94)
Query Neighborhood Hits	364	Target Neighborhood Hits	948	Shared Neighborhood Hits	153
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYST3_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.052631 (rank : 257)
Query Neighborhood Hits	364	Target Neighborhood Hits	772	Shared Neighborhood Hits	94
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.053796 (rank : 247)
Query Neighborhood Hits	364	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NALP5_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.064673 (rank : 162)
Query Neighborhood Hits	364	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NASP_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.099142 (rank : 70)
Query Neighborhood Hits	364	Target Neighborhood Hits	709	Shared Neighborhood Hits	134
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCOA6_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.053079 (rank : 251)
Query Neighborhood Hits	364	Target Neighborhood Hits	1202	Shared Neighborhood Hits	101
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NEST_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.057039 (rank : 220)
Query Neighborhood Hits	364	Target Neighborhood Hits	1305	Shared Neighborhood Hits	156
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NKTR_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.084838 (rank : 106)
Query Neighborhood Hits	364	Target Neighborhood Hits	658	Shared Neighborhood Hits	144
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NKTR_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.062669 (rank : 182)
Query Neighborhood Hits	364	Target Neighborhood Hits	417	Shared Neighborhood Hits	97
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NSBP1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.056908 (rank : 221)
Query Neighborhood Hits	364	Target Neighborhood Hits	251	Shared Neighborhood Hits	43
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.084222 (rank : 108)
Query Neighborhood Hits	364	Target Neighborhood Hits	681	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NSD1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.067880 (rank : 145)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

OGFR_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.064042 (rank : 173)
Query Neighborhood Hits	364	Target Neighborhood Hits	1582	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.064160 (rank : 170)
Query Neighborhood Hits	364	Target Neighborhood Hits	584	Shared Neighborhood Hits	82
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OXR1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.067673 (rank : 146)
Query Neighborhood Hits	364	Target Neighborhood Hits	516	Shared Neighborhood Hits	101
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PF21A_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.065609 (rank : 158)
Query Neighborhood Hits	364	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.063105 (rank : 181)
Query Neighborhood Hits	364	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.062382 (rank : 184)
Query Neighborhood Hits	364	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.064129 (rank : 171)
Query Neighborhood Hits	364	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.068984 (rank : 144)
Query Neighborhood Hits	364	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.070008 (rank : 138)
Query Neighborhood Hits	364	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.106706 (rank : 61)
Query Neighborhood Hits	364	Target Neighborhood Hits	394	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.128885 (rank : 48)
Query Neighborhood Hits	364	Target Neighborhood Hits	513	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PRP40_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.055732 (rank : 228)
Query Neighborhood Hits	364	Target Neighborhood Hits	442	Shared Neighborhood Hits	82
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

PRP40_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.057798 (rank : 217)
Query Neighborhood Hits	364	Target Neighborhood Hits	447	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

R51A1_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.063680 (rank : 175)
Query Neighborhood Hits	364	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RGS3_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.054492 (rank : 237)
Query Neighborhood Hits	364	Target Neighborhood Hits	1621	Shared Neighborhood Hits	131
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RPTN_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.056480 (rank : 224)
Query Neighborhood Hits	364	Target Neighborhood Hits	406	Shared Neighborhood Hits	77
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

RPTN_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.059509 (rank : 203)
Query Neighborhood Hits	364	Target Neighborhood Hits	650	Shared Neighborhood Hits	113
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RRBP1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.061799 (rank : 189)
Query Neighborhood Hits	364	Target Neighborhood Hits	1306	Shared Neighborhood Hits	149
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RSF1_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.096192 (rank : 81)
Query Neighborhood Hits	364	Target Neighborhood Hits	539	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SELPL_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.063163 (rank : 180)
Query Neighborhood Hits	364	Target Neighborhood Hits	588	Shared Neighborhood Hits	83
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEMG2_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.064378 (rank : 166)
Query Neighborhood Hits	364	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SFRIP_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.097547 (rank : 77)
Query Neighborhood Hits	364	Target Neighborhood Hits	530	Shared Neighborhood Hits	109
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SMC1A_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.050169 (rank : 275)
Query Neighborhood Hits	364	Target Neighborhood Hits	1384	Shared Neighborhood Hits	146
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.054538 (rank : 236)
Query Neighborhood Hits	364	Target Neighborhood Hits	1405	Shared Neighborhood Hits	165
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SON_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.056384 (rank : 225)
Query Neighborhood Hits	364	Target Neighborhood Hits	1568	Shared Neighborhood Hits	121
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.053865 (rank : 246)
Query Neighborhood Hits	364	Target Neighborhood Hits	957	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SP110_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.063227 (rank : 179)
Query Neighborhood Hits	364	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

STMN1_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.050767 (rank : 268)
Query Neighborhood Hits	364	Target Neighborhood Hits	554	Shared Neighborhood Hits	102
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

STMN1_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.050470 (rank : 272)
Query Neighborhood Hits	364	Target Neighborhood Hits	560	Shared Neighborhood Hits	103
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

SYCP2_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.059321 (rank : 207)
Query Neighborhood Hits	364	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TAF3_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.054359 (rank : 240)
Query Neighborhood Hits	364	Target Neighborhood Hits	568	Shared Neighborhood Hits	75
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.051519 (rank : 265)
Query Neighborhood Hits	364	Target Neighborhood Hits	463	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARA_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.086035 (rank : 103)
Query Neighborhood Hits	364	Target Neighborhood Hits	1626	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCAL5_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.124447 (rank : 49)
Query Neighborhood Hits	364	Target Neighborhood Hits	806	Shared Neighborhood Hits	159
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCOF_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.058596 (rank : 214)
Query Neighborhood Hits	364	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCRG1_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.066555 (rank : 154)
Query Neighborhood Hits	364	Target Neighborhood Hits	929	Shared Neighborhood Hits	143
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.067297 (rank : 150)
Query Neighborhood Hits	364	Target Neighborhood Hits	947	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TGON1_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.061014 (rank : 193)
Query Neighborhood Hits	364	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.066534 (rank : 155)
Query Neighborhood Hits	364	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TIF1A_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.052262 (rank : 260)
Query Neighborhood Hits	364	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.055479 (rank : 229)
Query Neighborhood Hits	364	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.056044 (rank : 226)
Query Neighborhood Hits	364	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TP53B_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.050325 (rank : 273)
Query Neighborhood Hits	364	Target Neighborhood Hits	413	Shared Neighborhood Hits	75
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.075860 (rank : 123)
Query Neighborhood Hits	364	Target Neighborhood Hits	644	Shared Neighborhood Hits	95
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TR150_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.077127 (rank : 120)
Query Neighborhood Hits	364	Target Neighborhood Hits	313	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRI66_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.059010 (rank : 210)
Query Neighborhood Hits	364	Target Neighborhood Hits	479	Shared Neighborhood Hits	39
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.059700 (rank : 201)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TTC16_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.064524 (rank : 164)
Query Neighborhood Hits	364	Target Neighborhood Hits	417	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TXND2_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.112432 (rank : 55)
Query Neighborhood Hits	364	Target Neighborhood Hits	793	Shared Neighborhood Hits	133
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

VPS72_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.051048 (rank : 267)
Query Neighborhood Hits	364	Target Neighborhood Hits	274	Shared Neighborhood Hits	57
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.060308 (rank : 196)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ZCPW1_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.057578 (rank : 218)
Query Neighborhood Hits	364	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ZMY11_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.063607 (rank : 176)
Query Neighborhood Hits	364	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.061481 (rank : 191)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

TTF2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	364	Target Neighborhood Hits	364	Shared Neighborhood Hits	364
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TTF2_HUMAN
NC score	0.940595 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	364	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

SMRCD_HUMAN
NC score	0.828509 (rank : 3)	θ value	6.82597e-32 (rank : 9)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

BTAF1_HUMAN
NC score	0.825131 (rank : 4)	θ value	7.06379e-29 (rank : 13)
Query Neighborhood Hits	364	Target Neighborhood Hits	97	Shared Neighborhood Hits	40
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMRCD_MOUSE
NC score	0.824645 (rank : 5)	θ value	1.57365e-28 (rank : 15)
Query Neighborhood Hits	364	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMCA1_HUMAN
NC score	0.818727 (rank : 6)	θ value	9.52487e-34 (rank : 7)
Query Neighborhood Hits	364	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.818380 (rank : 7)	θ value	5.0505e-35 (rank : 5)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA5_MOUSE
NC score	0.817442 (rank : 8)	θ value	4.27553e-34 (rank : 6)
Query Neighborhood Hits	364	Target Neighborhood Hits	80	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.816859 (rank : 9)	θ value	9.52487e-34 (rank : 8)
Query Neighborhood Hits	364	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

RA54B_HUMAN
NC score	0.816258 (rank : 10)	θ value	5.79196e-23 (rank : 22)
Query Neighborhood Hits	364	Target Neighborhood Hits	54	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.813784 (rank : 11)	θ value	1.6852e-22 (rank : 24)
Query Neighborhood Hits	364	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

ERCC6_HUMAN
NC score	0.813178 (rank : 12)	θ value	3.17815e-21 (rank : 26)
Query Neighborhood Hits	364	Target Neighborhood Hits	247	Shared Neighborhood Hits	83
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

RAD54_HUMAN
NC score	0.809046 (rank : 13)	θ value	6.18819e-25 (rank : 19)
Query Neighborhood Hits	364	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.804985 (rank : 14)	θ value	3.75424e-22 (rank : 25)
Query Neighborhood Hits	364	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD2_HUMAN
NC score	0.797339 (rank : 15)	θ value	1.57365e-28 (rank : 14)
Query Neighborhood Hits	364	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_MOUSE
NC score	0.793372 (rank : 16)	θ value	1.85889e-29 (rank : 12)
Query Neighborhood Hits	364	Target Neighborhood Hits	266	Shared Neighborhood Hits	64
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
NC score	0.793120 (rank : 17)	θ value	4.89182e-30 (rank : 10)
Query Neighborhood Hits	364	Target Neighborhood Hits	337	Shared Neighborhood Hits	76
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
NC score	0.792723 (rank : 18)	θ value	1.4233e-29 (rank : 11)
Query Neighborhood Hits	364	Target Neighborhood Hits	235	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD6_HUMAN
NC score	0.792057 (rank : 19)	θ value	2.27234e-27 (rank : 16)
Query Neighborhood Hits	364	Target Neighborhood Hits	342	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

INOC1_HUMAN
NC score	0.791748 (rank : 20)	θ value	3.07116e-24 (rank : 20)
Query Neighborhood Hits	364	Target Neighborhood Hits	181	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
NC score	0.791640 (rank : 21)	θ value	8.93572e-24 (rank : 21)
Query Neighborhood Hits	364	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

CHD9_MOUSE
NC score	0.789826 (rank : 22)	θ value	1.92365e-26 (rank : 17)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
NC score	0.780600 (rank : 23)	θ value	3.28125e-26 (rank : 18)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	63
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

SMCA2_HUMAN
NC score	0.770411 (rank : 24)	θ value	7.56453e-23 (rank : 23)
Query Neighborhood Hits	364	Target Neighborhood Hits	503	Shared Neighborhood Hits	86
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.758405 (rank : 25)	θ value	1.2077e-20 (rank : 27)
Query Neighborhood Hits	364	Target Neighborhood Hits	597	Shared Neighborhood Hits	100
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMRA3_MOUSE
NC score	0.755883 (rank : 26)	θ value	1.98146e-39 (rank : 3)
Query Neighborhood Hits	364	Target Neighborhood Hits	267	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.752928 (rank : 27)	θ value	7.52953e-39 (rank : 4)
Query Neighborhood Hits	364	Target Neighborhood Hits	265	Shared Neighborhood Hits	43
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMAL1_MOUSE
NC score	0.737191 (rank : 28)	θ value	1.86753e-13 (rank : 35)
Query Neighborhood Hits	364	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMAL1_HUMAN
NC score	0.736620 (rank : 29)	θ value	9.90251e-15 (rank : 34)
Query Neighborhood Hits	364	Target Neighborhood Hits	174	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CHD4_MOUSE
NC score	0.717372 (rank : 30)	θ value	1.47631e-18 (rank : 29)
Query Neighborhood Hits	364	Target Neighborhood Hits	408	Shared Neighborhood Hits	75
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.716710 (rank : 31)	θ value	3.07829e-16 (rank : 31)
Query Neighborhood Hits	364	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.716531 (rank : 32)	θ value	1.47631e-18 (rank : 28)
Query Neighborhood Hits	364	Target Neighborhood Hits	365	Shared Neighborhood Hits	64
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.713614 (rank : 33)	θ value	1.63225e-17 (rank : 30)
Query Neighborhood Hits	364	Target Neighborhood Hits	349	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

EP400_HUMAN
NC score	0.696326 (rank : 34)	θ value	3.52202e-12 (rank : 37)
Query Neighborhood Hits	364	Target Neighborhood Hits	556	Shared Neighborhood Hits	73
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.693006 (rank : 35)	θ value	2.43908e-13 (rank : 36)
Query Neighborhood Hits	364	Target Neighborhood Hits	592	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ATRX_MOUSE
NC score	0.660294 (rank : 36)	θ value	6.85773e-16 (rank : 32)
Query Neighborhood Hits	364	Target Neighborhood Hits	682	Shared Neighborhood Hits	133
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.639655 (rank : 37)	θ value	3.40345e-15 (rank : 33)
Query Neighborhood Hits	364	Target Neighborhood Hits	842	Shared Neighborhood Hits	149
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

NIPBL_HUMAN
NC score	0.188484 (rank : 38)	θ value	0.0563607 (rank : 80)
Query Neighborhood Hits	364	Target Neighborhood Hits	1311	Shared Neighborhood Hits	214
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.188190 (rank : 39)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	364	Target Neighborhood Hits	1041	Shared Neighborhood Hits	197
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TGON2_HUMAN
NC score	0.171630 (rank : 40)	θ value	0.0961366 (rank : 90)
Query Neighborhood Hits	364	Target Neighborhood Hits	1037	Shared Neighborhood Hits	170
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
NC score	0.161377 (rank : 41)	θ value	0.0563607 (rank : 81)
Query Neighborhood Hits	364	Target Neighborhood Hits	828	Shared Neighborhood Hits	168
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

IWS1_MOUSE
NC score	0.156979 (rank : 42)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	364	Target Neighborhood Hits	1258	Shared Neighborhood Hits	199
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBBP6_HUMAN
NC score	0.153705 (rank : 43)	θ value	1.38821 (rank : 191)
Query Neighborhood Hits	364	Target Neighborhood Hits	1135	Shared Neighborhood Hits	181
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

IWS1_HUMAN
NC score	0.153507 (rank : 44)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	364	Target Neighborhood Hits	1241	Shared Neighborhood Hits	188
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBBP6_MOUSE
NC score	0.149866 (rank : 45)	θ value	1.38821 (rank : 192)
Query Neighborhood Hits	364	Target Neighborhood Hits	1014	Shared Neighborhood Hits	167
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

LEO1_HUMAN
NC score	0.135560 (rank : 46)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	364	Target Neighborhood Hits	958	Shared Neighborhood Hits	160
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
NC score	0.131336 (rank : 47)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	364	Target Neighborhood Hits	946	Shared Neighborhood Hits	160
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PHF20_MOUSE
NC score	0.128885 (rank : 48)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	364	Target Neighborhood Hits	513	Shared Neighborhood Hits	146
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TCAL5_HUMAN
NC score	0.124447 (rank : 49)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	364	Target Neighborhood Hits	806	Shared Neighborhood Hits	159
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

AKA12_HUMAN
NC score	0.123595 (rank : 50)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	364	Target Neighborhood Hits	825	Shared Neighborhood Hits	149
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MAP1A_HUMAN
NC score	0.119572 (rank : 51)	θ value	0.125558 (rank : 94)
Query Neighborhood Hits	364	Target Neighborhood Hits	1626	Shared Neighborhood Hits	200
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SFR11_HUMAN
NC score	0.117137 (rank : 52)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	364	Target Neighborhood Hits	246	Shared Neighborhood Hits	49
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

NEIL3_HUMAN
NC score	0.116157 (rank : 53)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	364	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

SRRM2_MOUSE
NC score	0.115523 (rank : 54)	θ value	0.00175202 (rank : 45)
Query Neighborhood Hits	364	Target Neighborhood Hits	1470	Shared Neighborhood Hits	160
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TXND2_HUMAN
NC score	0.112432 (rank : 55)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	364	Target Neighborhood Hits	793	Shared Neighborhood Hits	133
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TR150_MOUSE
NC score	0.112207 (rank : 56)	θ value	1.38821 (rank : 201)
Query Neighborhood Hits	364	Target Neighborhood Hits	468	Shared Neighborhood Hits	135
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

LAD1_MOUSE
NC score	0.111641 (rank : 57)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	364	Target Neighborhood Hits	391	Shared Neighborhood Hits	104
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MBB1A_HUMAN
NC score	0.110528 (rank : 58)	θ value	0.00869519 (rank : 55)
Query Neighborhood Hits	364	Target Neighborhood Hits	665	Shared Neighborhood Hits	119
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NEIL3_MOUSE
NC score	0.109859 (rank : 59)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	364	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

SRRM2_HUMAN
NC score	0.106887 (rank : 60)	θ value	0.0330416 (rank : 71)
Query Neighborhood Hits	364	Target Neighborhood Hits	1296	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PHF20_HUMAN
NC score	0.106706 (rank : 61)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	364	Target Neighborhood Hits	394	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PKCB1_HUMAN
NC score	0.105898 (rank : 62)	θ value	1.81305 (rank : 211)
Query Neighborhood Hits	364	Target Neighborhood Hits	488	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

MDC1_HUMAN
NC score	0.104112 (rank : 63)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	364	Target Neighborhood Hits	1446	Shared Neighborhood Hits	188
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ZN318_MOUSE
NC score	0.103950 (rank : 64)	θ value	0.279714 (rank : 117)
Query Neighborhood Hits	364	Target Neighborhood Hits	642	Shared Neighborhood Hits	114
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

NFH_MOUSE
NC score	0.102935 (rank : 65)	θ value	0.0961366 (rank : 87)
Query Neighborhood Hits	364	Target Neighborhood Hits	2247	Shared Neighborhood Hits	219
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

YTDC1_HUMAN
NC score	0.102437 (rank : 66)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	364	Target Neighborhood Hits	458	Shared Neighborhood Hits	95
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CYLC1_HUMAN
NC score	0.102313 (rank : 67)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	364	Target Neighborhood Hits	408	Shared Neighborhood Hits	61
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RL1D1_HUMAN
NC score	0.102277 (rank : 68)	θ value	0.0148317 (rank : 60)
Query Neighborhood Hits	364	Target Neighborhood Hits	180	Shared Neighborhood Hits	55
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

KI67_HUMAN
NC score	0.100387 (rank : 69)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	364	Target Neighborhood Hits	581	Shared Neighborhood Hits	117
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

NASP_HUMAN
NC score	0.099142 (rank : 70)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	364	Target Neighborhood Hits	709	Shared Neighborhood Hits	134
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ICAL_HUMAN
NC score	0.098919 (rank : 71)	θ value	0.365318 (rank : 121)
Query Neighborhood Hits	364	Target Neighborhood Hits	275	Shared Neighborhood Hits	90
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MAP1B_MOUSE
NC score	0.098820 (rank : 72)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	364	Target Neighborhood Hits	977	Shared Neighborhood Hits	131
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MDN1_HUMAN
NC score	0.098202 (rank : 73)	θ value	0.0113563 (rank : 57)
Query Neighborhood Hits	364	Target Neighborhood Hits	662	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MAP1B_HUMAN
NC score	0.098199 (rank : 74)	θ value	0.0563607 (rank : 78)
Query Neighborhood Hits	364	Target Neighborhood Hits	903	Shared Neighborhood Hits	114
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

BPTF_HUMAN
NC score	0.097822 (rank : 75)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	364	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SFR12_MOUSE
NC score	0.097716 (rank : 76)	θ value	0.0330416 (rank : 70)
Query Neighborhood Hits	364	Target Neighborhood Hits	486	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFRIP_HUMAN
NC score	0.097547 (rank : 77)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	364	Target Neighborhood Hits	530	Shared Neighborhood Hits	109
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SRRM1_MOUSE
NC score	0.096683 (rank : 78)	θ value	0.365318 (rank : 127)
Query Neighborhood Hits	364	Target Neighborhood Hits	966	Shared Neighborhood Hits	117
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BSN_MOUSE
NC score	0.096310 (rank : 79)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	364	Target Neighborhood Hits	2057	Shared Neighborhood Hits	138
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CF010_HUMAN
NC score	0.096244 (rank : 80)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	364	Target Neighborhood Hits	329	Shared Neighborhood Hits	92
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

RSF1_HUMAN
NC score	0.096192 (rank : 81)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	364	Target Neighborhood Hits	539	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PCLO_HUMAN
NC score	0.096124 (rank : 82)	θ value	0.0431538 (rank : 72)
Query Neighborhood Hits	364	Target Neighborhood Hits	2046	Shared Neighborhood Hits	177
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CJ012_HUMAN
NC score	0.095181 (rank : 83)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	364	Target Neighborhood Hits	467	Shared Neighborhood Hits	104
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MDC1_MOUSE
NC score	0.094883 (rank : 84)	θ value	0.0563607 (rank : 79)
Query Neighborhood Hits	364	Target Neighborhood Hits	998	Shared Neighborhood Hits	130
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCLO_MOUSE
NC score	0.093845 (rank : 85)	θ value	0.0961366 (rank : 89)
Query Neighborhood Hits	364	Target Neighborhood Hits	2275	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

BSN_HUMAN
NC score	0.093156 (rank : 86)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	364	Target Neighborhood Hits	1537	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

ZC313_HUMAN
NC score	0.092844 (rank : 87)	θ value	1.81305 (rank : 216)
Query Neighborhood Hits	364	Target Neighborhood Hits	772	Shared Neighborhood Hits	131
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ACINU_HUMAN
NC score	0.092741 (rank : 88)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	364	Target Neighborhood Hits	828	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SFR12_HUMAN
NC score	0.092419 (rank : 89)	θ value	0.00869519 (rank : 56)
Query Neighborhood Hits	364	Target Neighborhood Hits	553	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

LAD1_HUMAN
NC score	0.092271 (rank : 90)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	364	Target Neighborhood Hits	441	Shared Neighborhood Hits	91
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

NOP14_HUMAN
NC score	0.091936 (rank : 91)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	364	Target Neighborhood Hits	573	Shared Neighborhood Hits	119
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

CCD55_MOUSE
NC score	0.091277 (rank : 92)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	364	Target Neighborhood Hits	519	Shared Neighborhood Hits	116
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

AFF4_HUMAN
NC score	0.090550 (rank : 93)	θ value	6.88961 (rank : 308)
Query Neighborhood Hits	364	Target Neighborhood Hits	611	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

MPP8_HUMAN
NC score	0.090487 (rank : 94)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	364	Target Neighborhood Hits	948	Shared Neighborhood Hits	153
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ELOA1_HUMAN
NC score	0.090206 (rank : 95)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	364	Target Neighborhood Hits	388	Shared Neighborhood Hits	105
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

CCD55_HUMAN
NC score	0.089532 (rank : 96)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	364	Target Neighborhood Hits	513	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ZN318_HUMAN
NC score	0.089368 (rank : 97)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	364	Target Neighborhood Hits	497	Shared Neighborhood Hits	81
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

NOLC1_HUMAN
NC score	0.089335 (rank : 98)	θ value	0.21417 (rank : 106)
Query Neighborhood Hits	364	Target Neighborhood Hits	452	Shared Neighborhood Hits	63
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BAZ1B_HUMAN
NC score	0.088806 (rank : 99)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	364	Target Neighborhood Hits	701	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

RRBP1_MOUSE
NC score	0.088717 (rank : 100)	θ value	1.38821 (rank : 195)
Query Neighborhood Hits	364	Target Neighborhood Hits	1650	Shared Neighborhood Hits	197
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ARS2_HUMAN
NC score	0.087517 (rank : 101)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	364	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

MINT_MOUSE
NC score	0.086935 (rank : 102)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	364	Target Neighborhood Hits	1514	Shared Neighborhood Hits	185
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TARA_HUMAN
NC score	0.086035 (rank : 103)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	364	Target Neighborhood Hits	1626	Shared Neighborhood Hits	167
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CYLC2_HUMAN
NC score	0.085903 (rank : 104)	θ value	1.38821 (rank : 184)
Query Neighborhood Hits	364	Target Neighborhood Hits	223	Shared Neighborhood Hits	43
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

NUCKS_HUMAN
NC score	0.085468 (rank : 105)	θ value	0.125558 (rank : 95)
Query Neighborhood Hits	364	Target Neighborhood Hits	143	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NKTR_HUMAN
NC score	0.084838 (rank : 106)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	364	Target Neighborhood Hits	658	Shared Neighborhood Hits	144
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

DNMT1_HUMAN
NC score	0.084471 (rank : 107)	θ value	0.0961366 (rank : 86)
Query Neighborhood Hits	364	Target Neighborhood Hits	401	Shared Neighborhood Hits	89
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

NSBP1_MOUSE
NC score	0.084222 (rank : 108)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	364	Target Neighborhood Hits	681	Shared Neighborhood Hits	111
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NTBP1_MOUSE
NC score	0.083279 (rank : 109)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	364	Target Neighborhood Hits	528	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

AFF4_MOUSE
NC score	0.083156 (rank : 110)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	364	Target Neighborhood Hits	581	Shared Neighborhood Hits	123
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TTF1_MOUSE
NC score	0.083083 (rank : 111)	θ value	2.36792 (rank : 232)
Query Neighborhood Hits	364	Target Neighborhood Hits	277	Shared Neighborhood Hits	88
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

THOC2_HUMAN
NC score	0.082905 (rank : 112)	θ value	0.365318 (rank : 129)
Query Neighborhood Hits	364	Target Neighborhood Hits	337	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ARS2_MOUSE
NC score	0.082469 (rank : 113)	θ value	0.0252991 (rank : 66)
Query Neighborhood Hits	364	Target Neighborhood Hits	212	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

PPIG_HUMAN
NC score	0.081900 (rank : 114)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	364	Target Neighborhood Hits	670	Shared Neighborhood Hits	125
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

SRRM1_HUMAN
NC score	0.080703 (rank : 115)	θ value	1.38821 (rank : 199)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ADDB_MOUSE
NC score	0.079525 (rank : 116)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	364	Target Neighborhood Hits	574	Shared Neighborhood Hits	137
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BASP_MOUSE
NC score	0.078836 (rank : 117)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	364	Target Neighborhood Hits	260	Shared Neighborhood Hits	38
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_HUMAN
NC score	0.078350 (rank : 118)	θ value	0.125558 (rank : 92)
Query Neighborhood Hits	364	Target Neighborhood Hits	321	Shared Neighborhood Hits	48
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

C8AP2_HUMAN
NC score	0.078223 (rank : 119)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	364	Target Neighborhood Hits	548	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

TR150_HUMAN
NC score	0.077127 (rank : 120)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	364	Target Neighborhood Hits	313	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

DMP1_MOUSE
NC score	0.076473 (rank : 121)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	364	Target Neighborhood Hits	498	Shared Neighborhood Hits	73
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

NSD1_MOUSE
NC score	0.076069 (rank : 122)	θ value	0.813845 (rank : 159)
Query Neighborhood Hits	364	Target Neighborhood Hits	472	Shared Neighborhood Hits	58
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TP53B_MOUSE
NC score	0.075860 (rank : 123)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	364	Target Neighborhood Hits	644	Shared Neighborhood Hits	95
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

HIRP3_HUMAN
NC score	0.075693 (rank : 124)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	364	Target Neighborhood Hits	323	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

MLL3_HUMAN
NC score	0.075634 (rank : 125)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	364	Target Neighborhood Hits	1644	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MINT_HUMAN
NC score	0.075016 (rank : 126)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	364	Target Neighborhood Hits	1291	Shared Neighborhood Hits	163
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BAZ1A_HUMAN
NC score	0.074840 (rank : 127)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	364	Target Neighborhood Hits	693	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

MLL2_HUMAN
NC score	0.074834 (rank : 128)	θ value	0.279714 (rank : 112)
Query Neighborhood Hits	364	Target Neighborhood Hits	1788	Shared Neighborhood Hits	130
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ARI5B_HUMAN
NC score	0.074477 (rank : 129)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	364	Target Neighborhood Hits	328	Shared Neighborhood Hits	107
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

NACAM_MOUSE
NC score	0.073244 (rank : 130)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	364	Target Neighborhood Hits	1866	Shared Neighborhood Hits	139
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TCOF_MOUSE
NC score	0.073104 (rank : 131)	θ value	0.0736092 (rank : 84)
Query Neighborhood Hits	364	Target Neighborhood Hits	471	Shared Neighborhood Hits	61
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

AIRE_MOUSE
NC score	0.072780 (rank : 132)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	364	Target Neighborhood Hits	196	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PRRT3_HUMAN
NC score	0.071798 (rank : 133)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	364	Target Neighborhood Hits	998	Shared Neighborhood Hits	76
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

GPTC8_HUMAN
NC score	0.071441 (rank : 134)	θ value	1.38821 (rank : 186)
Query Neighborhood Hits	364	Target Neighborhood Hits	366	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TEX2_MOUSE
NC score	0.071175 (rank : 135)	θ value	0.00390308 (rank : 50)
Query Neighborhood Hits	364	Target Neighborhood Hits	121	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

AIRE_HUMAN
NC score	0.071073 (rank : 136)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	364	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

NFH_HUMAN
NC score	0.070473 (rank : 137)	θ value	2.44474e-05 (rank : 39)
Query Neighborhood Hits	364	Target Neighborhood Hits	1242	Shared Neighborhood Hits	131
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF12_MOUSE
NC score	0.070008 (rank : 138)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	364	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ1B_MOUSE
NC score	0.069810 (rank : 139)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	364	Target Neighborhood Hits	394	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

RBM25_HUMAN
NC score	0.069630 (rank : 140)	θ value	0.0193708 (rank : 65)
Query Neighborhood Hits	364	Target Neighborhood Hits	682	Shared Neighborhood Hits	81
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

MLL3_MOUSE
NC score	0.069529 (rank : 141)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	364	Target Neighborhood Hits	1399	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SMOO_HUMAN
NC score	0.069495 (rank : 142)	θ value	1.43324e-05 (rank : 38)
Query Neighborhood Hits	364	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

MYST4_HUMAN
NC score	0.069127 (rank : 143)	θ value	0.0193708 (rank : 64)
Query Neighborhood Hits	364	Target Neighborhood Hits	671	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PHF12_HUMAN
NC score	0.068984 (rank : 144)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	364	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

NSD1_HUMAN
NC score	0.067880 (rank : 145)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	63
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

OXR1_MOUSE
NC score	0.067673 (rank : 146)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	364	Target Neighborhood Hits	516	Shared Neighborhood Hits	101
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

DMP1_HUMAN
NC score	0.067437 (rank : 147)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PRPC_HUMAN
NC score	0.067421 (rank : 148)	θ value	0.125558 (rank : 96)
Query Neighborhood Hits	364	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

TEX2_HUMAN
NC score	0.067405 (rank : 149)	θ value	0.0431538 (rank : 75)
Query Neighborhood Hits	364	Target Neighborhood Hits	106	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TCRG1_MOUSE
NC score	0.067297 (rank : 150)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	364	Target Neighborhood Hits	947	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

CBX5_HUMAN
NC score	0.067289 (rank : 151)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	364	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

HRX_HUMAN
NC score	0.067238 (rank : 152)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	364	Target Neighborhood Hits	825	Shared Neighborhood Hits	95
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SRCH_HUMAN
NC score	0.066812 (rank : 153)	θ value	0.21417 (rank : 107)
Query Neighborhood Hits	364	Target Neighborhood Hits	225	Shared Neighborhood Hits	33
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TCRG1_HUMAN
NC score	0.066555 (rank : 154)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	364	Target Neighborhood Hits	929	Shared Neighborhood Hits	143
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TGON2_MOUSE
NC score	0.066534 (rank : 155)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	364	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ALO17_HUMAN
NC score	0.066306 (rank : 156)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	364	Target Neighborhood Hits	317	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CJ078_MOUSE
NC score	0.066166 (rank : 157)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	364	Target Neighborhood Hits	559	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

PF21A_HUMAN
NC score	0.065609 (rank : 158)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	364	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

BRD4_MOUSE
NC score	0.065427 (rank : 159)	θ value	0.0736092 (rank : 82)
Query Neighborhood Hits	364	Target Neighborhood Hits	845	Shared Neighborhood Hits	91
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SPRL1_MOUSE
NC score	0.065297 (rank : 160)	θ value	0.47712 (rank : 138)
Query Neighborhood Hits	364	Target Neighborhood Hits	403	Shared Neighborhood Hits	82
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

BRD4_HUMAN
NC score	0.064796 (rank : 161)	θ value	0.125558 (rank : 93)
Query Neighborhood Hits	364	Target Neighborhood Hits	851	Shared Neighborhood Hits	87
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

NALP5_MOUSE
NC score	0.064673 (rank : 162)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	364	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

FILA_HUMAN
NC score	0.064543 (rank : 163)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	364	Target Neighborhood Hits	685	Shared Neighborhood Hits	76
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TTC16_HUMAN
NC score	0.064524 (rank : 164)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	364	Target Neighborhood Hits	417	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

T2FA_HUMAN
NC score	0.064502 (rank : 165)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	364	Target Neighborhood Hits	228	Shared Neighborhood Hits	46
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

SEMG2_HUMAN
NC score	0.064378 (rank : 166)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	364	Target Neighborhood Hits	251	Shared Neighborhood Hits	59
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

TARA_MOUSE
NC score	0.064285 (rank : 167)	θ value	1.38821 (rank : 200)
Query Neighborhood Hits	364	Target Neighborhood Hits	1133	Shared Neighborhood Hits	127
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NCOR1_HUMAN
NC score	0.064267 (rank : 168)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	364	Target Neighborhood Hits	577	Shared Neighborhood Hits	81
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
NC score	0.064173 (rank : 169)	θ value	0.163984 (rank : 101)
Query Neighborhood Hits	364	Target Neighborhood Hits	521	Shared Neighborhood Hits	76
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

OGFR_MOUSE
NC score	0.064160 (rank : 170)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	364	Target Neighborhood Hits	584	Shared Neighborhood Hits	82
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PF21B_MOUSE
NC score	0.064129 (rank : 171)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	364	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

NCOR2_HUMAN
NC score	0.064084 (rank : 172)	θ value	1.38821 (rank : 189)
Query Neighborhood Hits	364	Target Neighborhood Hits	870	Shared Neighborhood Hits	108
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

OGFR_HUMAN
NC score	0.064042 (rank : 173)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	364	Target Neighborhood Hits	1582	Shared Neighborhood Hits	112
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PELP1_HUMAN
NC score	0.063776 (rank : 174)	θ value	0.00509761 (rank : 52)
Query Neighborhood Hits	364	Target Neighborhood Hits	596	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

R51A1_MOUSE
NC score	0.063680 (rank : 175)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	364	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

ZMY11_HUMAN
NC score	0.063607 (rank : 176)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	364	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

NCOR2_MOUSE
NC score	0.063357 (rank : 177)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	364	Target Neighborhood Hits	790	Shared Neighborhood Hits	97
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RENT2_HUMAN
NC score	0.063261 (rank : 178)	θ value	0.0252991 (rank : 67)
Query Neighborhood Hits	364	Target Neighborhood Hits	618	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SP110_HUMAN
NC score	0.063227 (rank : 179)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	364	Target Neighborhood Hits	141	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SELPL_MOUSE
NC score	0.063163 (rank : 180)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	364	Target Neighborhood Hits	588	Shared Neighborhood Hits	83
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PF21A_MOUSE
NC score	0.063105 (rank : 181)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	364	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

NKTR_MOUSE
NC score	0.062669 (rank : 182)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	364	Target Neighborhood Hits	417	Shared Neighborhood Hits	97
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

CT2NL_HUMAN
NC score	0.062666 (rank : 183)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	364	Target Neighborhood Hits	1059	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PF21B_HUMAN
NC score	0.062382 (rank : 184)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	364	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

CIR_MOUSE
NC score	0.062181 (rank : 185)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	364	Target Neighborhood Hits	255	Shared Neighborhood Hits	40
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

ESCO1_HUMAN
NC score	0.061967 (rank : 186)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	364	Target Neighborhood Hits	361	Shared Neighborhood Hits	77
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RIF1_MOUSE
NC score	0.061962 (rank : 187)	θ value	0.0736092 (rank : 83)
Query Neighborhood Hits	364	Target Neighborhood Hits	315	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ANR11_HUMAN
NC score	0.061842 (rank : 188)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	364	Target Neighborhood Hits	1289	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

RRBP1_HUMAN
NC score	0.061799 (rank : 189)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	364	Target Neighborhood Hits	1306	Shared Neighborhood Hits	149
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

TRDN_HUMAN
NC score	0.061762 (rank : 190)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	364	Target Neighborhood Hits	542	Shared Neighborhood Hits	72
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZMY11_MOUSE
NC score	0.061481 (rank : 191)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

MILK1_MOUSE
NC score	0.061180 (rank : 192)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	364	Target Neighborhood Hits	788	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TGON1_MOUSE
NC score	0.061014 (rank : 193)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	364	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

LRRF1_HUMAN
NC score	0.060968 (rank : 194)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	364	Target Neighborhood Hits	625	Shared Neighborhood Hits	80
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

RP1L1_HUMAN
NC score	0.060760 (rank : 195)	θ value	0.0431538 (rank : 73)
Query Neighborhood Hits	364	Target Neighborhood Hits	1072	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

VPS72_MOUSE
NC score	0.060308 (rank : 196)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	65
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MATR3_MOUSE
NC score	0.060128 (rank : 197)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	364	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

DSPP_MOUSE
NC score	0.059968 (rank : 198)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	72
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CCD91_HUMAN
NC score	0.059856 (rank : 199)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	364	Target Neighborhood Hits	868	Shared Neighborhood Hits	121
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

BCLF1_HUMAN
NC score	0.059714 (rank : 200)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	364	Target Neighborhood Hits	298	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NYF8, Q14673, Q86WU6, Q86WY0	Gene names	BCLAF1, BTF, KIAA0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

TRI66_MOUSE
NC score	0.059700 (rank : 201)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	364	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CCD96_MOUSE
NC score	0.059570 (rank : 202)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	364	Target Neighborhood Hits	704	Shared Neighborhood Hits	108
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RPTN_MOUSE
NC score	0.059509 (rank : 203)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	364	Target Neighborhood Hits	650	Shared Neighborhood Hits	113
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ENAH_HUMAN
NC score	0.059502 (rank : 204)	θ value	0.00020696 (rank : 40)
Query Neighborhood Hits	364	Target Neighborhood Hits	784	Shared Neighborhood Hits	81
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CBX5_MOUSE
NC score	0.059432 (rank : 205)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	364	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CIR_HUMAN
NC score	0.059406 (rank : 206)	θ value	0.47712 (rank : 130)
Query Neighborhood Hits	364	Target Neighborhood Hits	249	Shared Neighborhood Hits	36
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

SYCP2_HUMAN
NC score	0.059321 (rank : 207)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	364	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

AFF1_HUMAN
NC score	0.059083 (rank : 208)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	364	Target Neighborhood Hits	506	Shared Neighborhood Hits	68
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BAZ2B_HUMAN
NC score	0.059044 (rank : 209)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	364	Target Neighborhood Hits	803	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TRI66_HUMAN
NC score	0.059010 (rank : 210)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	364	Target Neighborhood Hits	479	Shared Neighborhood Hits	39
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

GRIN1_HUMAN
NC score	0.059007 (rank : 211)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	364	Target Neighborhood Hits	681	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DSPP_HUMAN
NC score	0.058965 (rank : 212)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	364	Target Neighborhood Hits	645	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SET1A_HUMAN
NC score	0.058716 (rank : 213)	θ value	1.81305 (rank : 214)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	74
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TCOF_HUMAN
NC score	0.058596 (rank : 214)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	364	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BAZ2A_MOUSE
NC score	0.058309 (rank : 215)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	364	Target Neighborhood Hits	744	Shared Neighborhood Hits	82
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ICAL_MOUSE
NC score	0.058079 (rank : 216)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	364	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

PRP40_MOUSE
NC score	0.057798 (rank : 217)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	364	Target Neighborhood Hits	447	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

ZCPW1_MOUSE
NC score	0.057578 (rank : 218)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	364	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

PSIP1_HUMAN
NC score	0.057356 (rank : 219)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	364	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

NEST_HUMAN
NC score	0.057039 (rank : 220)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	364	Target Neighborhood Hits	1305	Shared Neighborhood Hits	156
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NSBP1_HUMAN
NC score	0.056908 (rank : 221)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	364	Target Neighborhood Hits	251	Shared Neighborhood Hits	43
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NFM_HUMAN
NC score	0.056639 (rank : 222)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	364	Target Neighborhood Hits	1328	Shared Neighborhood Hits	152
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

INVO_MOUSE
NC score	0.056584 (rank : 223)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	364	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

RPTN_HUMAN
NC score	0.056480 (rank : 224)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	364	Target Neighborhood Hits	406	Shared Neighborhood Hits	77
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SON_HUMAN
NC score	0.056384 (rank : 225)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	364	Target Neighborhood Hits	1568	Shared Neighborhood Hits	121
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TIF1G_MOUSE
NC score	0.056044 (rank : 226)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	364	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

LARP1_HUMAN
NC score	0.055952 (rank : 227)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	364	Target Neighborhood Hits	242	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

PRP40_HUMAN
NC score	0.055732 (rank : 228)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	364	Target Neighborhood Hits	442	Shared Neighborhood Hits	82
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

TIF1A_MOUSE
NC score	0.055479 (rank : 229)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	364	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

CEP35_HUMAN
NC score	0.055230 (rank : 230)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	364	Target Neighborhood Hits	811	Shared Neighborhood Hits	121
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

MATR3_HUMAN
NC score	0.055184 (rank : 231)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	364	Target Neighborhood Hits	325	Shared Neighborhood Hits	86
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

SFRS4_MOUSE
NC score	0.055168 (rank : 232)	θ value	0.0431538 (rank : 74)
Query Neighborhood Hits	364	Target Neighborhood Hits	406	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

PRG4_HUMAN
NC score	0.055034 (rank : 233)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	364	Target Neighborhood Hits	764	Shared Neighborhood Hits	70
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CI039_HUMAN
NC score	0.054743 (rank : 234)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	364	Target Neighborhood Hits	1171	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ATN1_HUMAN
NC score	0.054664 (rank : 235)	θ value	0.365318 (rank : 119)
Query Neighborhood Hits	364	Target Neighborhood Hits	676	Shared Neighborhood Hits	60
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SMC2_HUMAN
NC score	0.054538 (rank : 236)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	364	Target Neighborhood Hits	1405	Shared Neighborhood Hits	165
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

RGS3_MOUSE
NC score	0.054492 (rank : 237)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	364	Target Neighborhood Hits	1621	Shared Neighborhood Hits	131
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SMC3_MOUSE
NC score	0.054451 (rank : 238)	θ value	0.163984 (rank : 103)
Query Neighborhood Hits	364	Target Neighborhood Hits	1187	Shared Neighborhood Hits	122
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.054429 (rank : 239)	θ value	0.163984 (rank : 102)
Query Neighborhood Hits	364	Target Neighborhood Hits	1186	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

TAF3_HUMAN
NC score	0.054359 (rank : 240)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	364	Target Neighborhood Hits	568	Shared Neighborhood Hits	75
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

MAP9_MOUSE
NC score	0.054346 (rank : 241)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	364	Target Neighborhood Hits	529	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

DMN_HUMAN
NC score	0.054256 (rank : 242)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	364	Target Neighborhood Hits	690	Shared Neighborhood Hits	132
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

BAZ2A_HUMAN
NC score	0.054231 (rank : 243)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	364	Target Neighborhood Hits	780	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CROP_MOUSE
NC score	0.053964 (rank : 244)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	364	Target Neighborhood Hits	403	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

ERIC1_HUMAN
NC score	0.053951 (rank : 245)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	364	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

SON_MOUSE
NC score	0.053865 (rank : 246)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	364	Target Neighborhood Hits	957	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MYST3_MOUSE
NC score	0.053796 (rank : 247)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	364	Target Neighborhood Hits	688	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

ZN638_MOUSE
NC score	0.053599 (rank : 248)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	364	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

LY10_HUMAN
NC score	0.053521 (rank : 249)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	364	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

ACINU_MOUSE
NC score	0.053470 (rank : 250)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	364	Target Neighborhood Hits	712	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NCOA6_HUMAN
NC score	0.053079 (rank : 251)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	364	Target Neighborhood Hits	1202	Shared Neighborhood Hits	101
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CT2NL_MOUSE
NC score	0.053062 (rank : 252)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	364	Target Neighborhood Hits	902	Shared Neighborhood Hits	130
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CCD21_MOUSE
NC score	0.053020 (rank : 253)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	364	Target Neighborhood Hits	1135	Shared Neighborhood Hits	142
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD21_HUMAN
NC score	0.052911 (rank : 254)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	364	Target Neighborhood Hits	1228	Shared Neighborhood Hits	138
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CBX1_HUMAN
NC score	0.052720 (rank : 255)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	364	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.052720 (rank : 256)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	364	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

MYST3_HUMAN
NC score	0.052631 (rank : 257)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	364	Target Neighborhood Hits	772	Shared Neighborhood Hits	94
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PRG4_MOUSE
NC score	0.052610 (rank : 258)	θ value	0.365318 (rank : 125)
Query Neighborhood Hits	364	Target Neighborhood Hits	624	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GOGB1_HUMAN
NC score	0.052414 (rank : 259)	θ value	0.47712 (rank : 134)
Query Neighborhood Hits	364	Target Neighborhood Hits	2297	Shared Neighborhood Hits	183
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TIF1A_HUMAN
NC score	0.052262 (rank : 260)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	364	Target Neighborhood Hits	327	Shared Neighborhood Hits	21
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

BRD3_MOUSE
NC score	0.052203 (rank : 261)	θ value	5.27518 (rank : 281)
Query Neighborhood Hits	364	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

IF2P_HUMAN
NC score	0.052058 (rank : 262)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	364	Target Neighborhood Hits	889	Shared Neighborhood Hits	84
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

BRD3_HUMAN
NC score	0.051659 (rank : 263)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	364	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRCA1_MOUSE
NC score	0.051650 (rank : 264)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	364	Target Neighborhood Hits	436	Shared Neighborhood Hits	52
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TAF3_MOUSE
NC score	0.051519 (rank : 265)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	364	Target Neighborhood Hits	463	Shared Neighborhood Hits	68
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CAF1A_MOUSE
NC score	0.051384 (rank : 266)	θ value	4.03905 (rank : 259)
Query Neighborhood Hits	364	Target Neighborhood Hits	736	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

VPS72_HUMAN
NC score	0.051048 (rank : 267)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	364	Target Neighborhood Hits	274	Shared Neighborhood Hits	57
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

STMN1_HUMAN
NC score	0.050767 (rank : 268)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	364	Target Neighborhood Hits	554	Shared Neighborhood Hits	102
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

TOP3A_HUMAN
NC score	0.050721 (rank : 269)	θ value	0.47712 (rank : 139)
Query Neighborhood Hits	364	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

NFM_MOUSE
NC score	0.050680 (rank : 270)	θ value	0.000786445 (rank : 42)
Query Neighborhood Hits	364	Target Neighborhood Hits	1159	Shared Neighborhood Hits	123
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

BRD8_MOUSE
NC score	0.050530 (rank : 271)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	364	Target Neighborhood Hits	422	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

STMN1_MOUSE
NC score	0.050470 (rank : 272)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	364	Target Neighborhood Hits	560	Shared Neighborhood Hits	103
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

TP53B_HUMAN
NC score	0.050325 (rank : 273)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	364	Target Neighborhood Hits	413	Shared Neighborhood Hits	75
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CAF1A_HUMAN
NC score	0.050239 (rank : 274)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	364	Target Neighborhood Hits	750	Shared Neighborhood Hits	69
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SMC1A_MOUSE
NC score	0.050169 (rank : 275)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	364	Target Neighborhood Hits	1384	Shared Neighborhood Hits	146
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

DIDO1_HUMAN
NC score	0.050043 (rank : 276)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	364	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TOP3A_MOUSE
NC score	0.049193 (rank : 277)	θ value	0.21417 (rank : 109)
Query Neighborhood Hits	364	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

REN3B_HUMAN
NC score	0.048754 (rank : 278)	θ value	1.38821 (rank : 193)
Query Neighborhood Hits	364	Target Neighborhood Hits	412	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

CROP_HUMAN
NC score	0.048586 (rank : 279)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	364	Target Neighborhood Hits	402	Shared Neighborhood Hits	51
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

PELP1_MOUSE
NC score	0.048437 (rank : 280)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	364	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

JHD2C_MOUSE
NC score	0.048164 (rank : 281)	θ value	0.0193708 (rank : 63)
Query Neighborhood Hits	364	Target Neighborhood Hits	297	Shared Neighborhood Hits	52
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

ARI4A_HUMAN
NC score	0.047950 (rank : 282)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	364	Target Neighborhood Hits	434	Shared Neighborhood Hits	57
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

APEX2_HUMAN
NC score	0.047759 (rank : 283)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	364	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

IF4B_MOUSE
NC score	0.047272 (rank : 284)	θ value	0.365318 (rank : 122)
Query Neighborhood Hits	364	Target Neighborhood Hits	368	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MAP9_HUMAN
NC score	0.047148 (rank : 285)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	364	Target Neighborhood Hits	518	Shared Neighborhood Hits	71
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

BRD7_MOUSE
NC score	0.046427 (rank : 286)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	364	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

CABIN_HUMAN
NC score	0.046214 (rank : 287)	θ value	5.27518 (rank : 284)
Query Neighborhood Hits	364	Target Neighborhood Hits	490	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

APEX2_MOUSE
NC score	0.046207 (rank : 288)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	364	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

UBP8_HUMAN
NC score	0.046008 (rank : 289)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	364	Target Neighborhood Hits	751	Shared Neighborhood Hits	114
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

TPR_HUMAN
NC score	0.045304 (rank : 290)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	364	Target Neighborhood Hits	1921	Shared Neighborhood Hits	159
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

PRR12_HUMAN
NC score	0.045142 (rank : 291)	θ value	1.38821 (rank : 190)
Query Neighborhood Hits	364	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

NAF1_HUMAN
NC score	0.045014 (rank : 292)	θ value	5.27518 (rank : 295)
Query Neighborhood Hits	364	Target Neighborhood Hits	937	Shared Neighborhood Hits	108
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

DDX23_HUMAN
NC score	0.044361 (rank : 293)	θ value	0.47712 (rank : 132)
Query Neighborhood Hits	364	Target Neighborhood Hits	486	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

LYAR_MOUSE
NC score	0.043655 (rank : 294)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	364	Target Neighborhood Hits	153	Shared Neighborhood Hits	30
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

SFRS8_HUMAN
NC score	0.043527 (rank : 295)	θ value	1.38821 (rank : 197)
Query Neighborhood Hits	364	Target Neighborhood Hits	166	Shared Neighborhood Hits	29
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

DREB_MOUSE
NC score	0.043482 (rank : 296)	θ value	0.47712 (rank : 133)
Query Neighborhood Hits	364	Target Neighborhood Hits	446	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXS6, Q922X1, Q9QXS5	Gene names	Dbn1, Drba
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

CENPE_HUMAN
NC score	0.043284 (rank : 297)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	364	Target Neighborhood Hits	2060	Shared Neighborhood Hits	170
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

JHD2C_HUMAN
NC score	0.042896 (rank : 298)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	364	Target Neighborhood Hits	279	Shared Neighborhood Hits	51
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

ABCF1_HUMAN
NC score	0.042498 (rank : 299)	θ value	0.00509761 (rank : 51)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

DAXX_MOUSE
NC score	0.042222 (rank : 300)	θ value	0.21417 (rank : 105)
Query Neighborhood Hits	364	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

APC_HUMAN
NC score	0.041688 (rank : 301)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	364	Target Neighborhood Hits	603	Shared Neighborhood Hits	71
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

RPGR1_MOUSE
NC score	0.041602 (rank : 302)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	364	Target Neighborhood Hits	713	Shared Neighborhood Hits	66
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

AP3B1_MOUSE
NC score	0.041551 (rank : 303)	θ value	0.365318 (rank : 118)
Query Neighborhood Hits	364	Target Neighborhood Hits	302	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DREB_HUMAN
NC score	0.040840 (rank : 304)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	364	Target Neighborhood Hits	450	Shared Neighborhood Hits	45
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MARCS_HUMAN
NC score	0.040530 (rank : 305)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	364	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

STK10_MOUSE
NC score	0.040334 (rank : 306)	θ value	0.21417 (rank : 108)
Query Neighborhood Hits	364	Target Neighborhood Hits	2132	Shared Neighborhood Hits	187
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

INCE_MOUSE
NC score	0.040173 (rank : 307)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	364	Target Neighborhood Hits	903	Shared Neighborhood Hits	76
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

AP3D1_HUMAN
NC score	0.039800 (rank : 308)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	364	Target Neighborhood Hits	254	Shared Neighborhood Hits	44
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

TRHY_HUMAN
NC score	0.039060 (rank : 309)	θ value	0.0431538 (rank : 77)
Query Neighborhood Hits	364	Target Neighborhood Hits	1385	Shared Neighborhood Hits	93
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CUTL1_MOUSE
NC score	0.038859 (rank : 310)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	364	Target Neighborhood Hits	1620	Shared Neighborhood Hits	141
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CTR9_MOUSE
NC score	0.038730 (rank : 311)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	53
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

TNR6A_HUMAN
NC score	0.038700 (rank : 312)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	364	Target Neighborhood Hits	343	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SFR16_MOUSE
NC score	0.038542 (rank : 313)	θ value	1.81305 (rank : 215)
Query Neighborhood Hits	364	Target Neighborhood Hits	177	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CFC7, Q8CFC8, Q9Z2N3	Gene names	Sfrs16, Clasp, Swap2
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 16 (Suppressor of white-apricot homolog 2) (Clk4-associating SR-related protein).

TOP1_MOUSE
NC score	0.038092 (rank : 314)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	364	Target Neighborhood Hits	213	Shared Neighborhood Hits	32
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

XE7_HUMAN
NC score	0.037914 (rank : 315)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	364	Target Neighborhood Hits	738	Shared Neighborhood Hits	63
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

RRS1_HUMAN
NC score	0.037838 (rank : 316)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	10
SwissProt Accessions	Q15050, Q9BUX8	Gene names	RRS1, KIAA0112, RRR
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

CDYL2_HUMAN
NC score	0.037760 (rank : 317)	θ value	0.365318 (rank : 120)
Query Neighborhood Hits	364	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

MILK1_HUMAN
NC score	0.037682 (rank : 318)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	364	Target Neighborhood Hits	427	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PHAR3_HUMAN
NC score	0.037441 (rank : 319)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	364	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

RBP1_HUMAN
NC score	0.037316 (rank : 320)	θ value	0.0330416 (rank : 69)
Query Neighborhood Hits	364	Target Neighborhood Hits	521	Shared Neighborhood Hits	40
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

CS007_HUMAN
NC score	0.037204 (rank : 321)	θ value	4.03905 (rank : 261)
Query Neighborhood Hits	364	Target Neighborhood Hits	401	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

RBP1_MOUSE
NC score	0.036903 (rank : 322)	θ value	0.125558 (rank : 97)
Query Neighborhood Hits	364	Target Neighborhood Hits	493	Shared Neighborhood Hits	46
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

INCE_HUMAN
NC score	0.036889 (rank : 323)	θ value	1.38821 (rank : 187)
Query Neighborhood Hits	364	Target Neighborhood Hits	978	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

WDR60_HUMAN
NC score	0.036793 (rank : 324)	θ value	1.38821 (rank : 202)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

AP3B2_MOUSE
NC score	0.036610 (rank : 325)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	364	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

RERE_MOUSE
NC score	0.036582 (rank : 326)	θ value	1.81305 (rank : 213)
Query Neighborhood Hits	364	Target Neighborhood Hits	785	Shared Neighborhood Hits	62
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CSF1_HUMAN
NC score	0.036559 (rank : 327)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	364	Target Neighborhood Hits	258	Shared Neighborhood Hits	37
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

SMRC1_MOUSE
NC score	0.036450 (rank : 328)	θ value	1.38821 (rank : 198)
Query Neighborhood Hits	364	Target Neighborhood Hits	459	Shared Neighborhood Hits	68
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

KI21A_HUMAN
NC score	0.036252 (rank : 329)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	364	Target Neighborhood Hits	1543	Shared Neighborhood Hits	139
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

RRS1_MOUSE
NC score	0.035736 (rank : 330)	θ value	1.38821 (rank : 196)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CYH6, Q3UQW6, Q9CS27, Q9D2B2, Q9D6M6, Q9JJC1	Gene names	Rrs1, Rrr
Domain Architecture
Description	Ribosome biogenesis regulatory protein homolog.

CS007_MOUSE
NC score	0.035470 (rank : 331)	θ value	4.03905 (rank : 262)
Query Neighborhood Hits	364	Target Neighborhood Hits	464	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

TOP2A_HUMAN
NC score	0.035442 (rank : 332)	θ value	0.0431538 (rank : 76)
Query Neighborhood Hits	364	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

RIMS1_HUMAN
NC score	0.035407 (rank : 333)	θ value	1.38821 (rank : 194)
Query Neighborhood Hits	364	Target Neighborhood Hits	437	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

CENPF_HUMAN
NC score	0.035060 (rank : 334)	θ value	1.81305 (rank : 203)
Query Neighborhood Hits	364	Target Neighborhood Hits	1932	Shared Neighborhood Hits	160
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CCNL1_HUMAN
NC score	0.035035 (rank : 335)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	364	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

PEPL_MOUSE
NC score	0.034190 (rank : 336)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	364	Target Neighborhood Hits	1105	Shared Neighborhood Hits	114
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PHAR3_MOUSE
NC score	0.034032 (rank : 337)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	364	Target Neighborhood Hits	206	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

INVO_HUMAN
NC score	0.033633 (rank : 338)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	364	Target Neighborhood Hits	636	Shared Neighborhood Hits	55
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

ELOA3_HUMAN
NC score	0.033569 (rank : 339)	θ value	0.279714 (rank : 111)
Query Neighborhood Hits	364	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NG57	Gene names	TCEB3C, TCEB3L2
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A3 (Elongin-A3) (EloA3) (Transcription elongation factor B polypeptide 3C).

PPR3A_HUMAN
NC score	0.033355 (rank : 340)	θ value	0.47712 (rank : 137)
Query Neighborhood Hits	364	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

CN102_HUMAN
NC score	0.032940 (rank : 341)	θ value	0.47712 (rank : 131)
Query Neighborhood Hits	364	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H7Z3, Q9NWH6	Gene names	C14orf102
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102.

ITSN1_HUMAN
NC score	0.032785 (rank : 342)	θ value	5.27518 (rank : 294)
Query Neighborhood Hits	364	Target Neighborhood Hits	1757	Shared Neighborhood Hits	151
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
NC score	0.032580 (rank : 343)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	364	Target Neighborhood Hits	1669	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

NEB1_HUMAN
NC score	0.032274 (rank : 344)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	364	Target Neighborhood Hits	829	Shared Neighborhood Hits	99
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

DNL1_MOUSE
NC score	0.032196 (rank : 345)	θ value	5.27518 (rank : 291)
Query Neighborhood Hits	364	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

CCNL1_MOUSE
NC score	0.032104 (rank : 346)	θ value	4.03905 (rank : 260)
Query Neighborhood Hits	364	Target Neighborhood Hits	71	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CCAR1_HUMAN
NC score	0.032058 (rank : 347)	θ value	5.27518 (rank : 285)
Query Neighborhood Hits	364	Target Neighborhood Hits	444	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

SYN1_MOUSE
NC score	0.031729 (rank : 348)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	364	Target Neighborhood Hits	363	Shared Neighborhood Hits	32
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SMRC1_HUMAN
NC score	0.031288 (rank : 349)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	364	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

TTC14_HUMAN
NC score	0.031201 (rank : 350)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	364	Target Neighborhood Hits	274	Shared Neighborhood Hits	33
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

SIA7A_HUMAN
NC score	0.030699 (rank : 351)	θ value	2.36792 (rank : 230)
Query Neighborhood Hits	364	Target Neighborhood Hits	177	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NSC7, Q6UW90, Q9NSC6	Gene names	ST6GALNAC1, SIAT7A
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

MYH11_HUMAN
NC score	0.030492 (rank : 352)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	364	Target Neighborhood Hits	1806	Shared Neighborhood Hits	164
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NFRKB_HUMAN
NC score	0.029979 (rank : 353)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	364	Target Neighborhood Hits	211	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

CCNL2_HUMAN
NC score	0.029734 (rank : 354)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	364	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

KI21A_MOUSE
NC score	0.029138 (rank : 355)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	364	Target Neighborhood Hits	1317	Shared Neighborhood Hits	127
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

U2AFM_MOUSE
NC score	0.028303 (rank : 356)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	364	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

OS9_HUMAN
NC score	0.028291 (rank : 357)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	364	Target Neighborhood Hits	134	Shared Neighborhood Hits	27
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

RADI_HUMAN
NC score	0.028250 (rank : 358)	θ value	0.813845 (rank : 160)
Query Neighborhood Hits	364	Target Neighborhood Hits	741	Shared Neighborhood Hits	53
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

AZI1_MOUSE
NC score	0.027940 (rank : 359)	θ value	6.88961 (rank : 310)
Query Neighborhood Hits	364	Target Neighborhood Hits	990	Shared Neighborhood Hits	102
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BLNK_HUMAN
NC score	0.027935 (rank : 360)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	364	Target Neighborhood Hits	228	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WV28, O75498, O75499	Gene names	BLNK, BASH, SLP65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65).

RADI_MOUSE
NC score	0.027642 (rank : 361)	θ value	1.81305 (rank : 212)
Query Neighborhood Hits	364	Target Neighborhood Hits	773	Shared Neighborhood Hits	52
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

SFPQ_HUMAN
NC score	0.027586 (rank : 362)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	364	Target Neighborhood Hits	986	Shared Neighborhood Hits	74
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ST18_HUMAN
NC score	0.027472 (rank : 363)	θ value	0.365318 (rank : 128)
Query Neighborhood Hits	364	Target Neighborhood Hits	252	Shared Neighborhood Hits	26
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

SETB1_MOUSE
NC score	0.027323 (rank : 364)	θ value	0.279714 (rank : 116)
Query Neighborhood Hits	364	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TNC6B_HUMAN
NC score	0.027165 (rank : 365)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	364	Target Neighborhood Hits	256	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

CCD19_HUMAN
NC score	0.026713 (rank : 366)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	364	Target Neighborhood Hits	639	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

P66B_HUMAN
NC score	0.026537 (rank : 367)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	364	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

EZRI_HUMAN
NC score	0.026523 (rank : 368)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	364	Target Neighborhood Hits	663	Shared Neighborhood Hits	60
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CNKR1_HUMAN
NC score	0.026444 (rank : 369)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	364	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

NFL_HUMAN
NC score	0.025729 (rank : 370)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	364	Target Neighborhood Hits	666	Shared Neighborhood Hits	58
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PER3_HUMAN
NC score	0.025561 (rank : 371)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	364	Target Neighborhood Hits	479	Shared Neighborhood Hits	45
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SYEP_MOUSE
NC score	0.025294 (rank : 372)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	364	Target Neighborhood Hits	123	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

PAR3L_HUMAN
NC score	0.025149 (rank : 373)	θ value	0.0961366 (rank : 88)
Query Neighborhood Hits	364	Target Neighborhood Hits	297	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEW8, Q8IUC7, Q8IUC9, Q96DK9, Q96N09, Q96NX6, Q96NX7, Q96Q29	Gene names	PARD3B, ALS2CR19, PAR3B, PAR3L
Domain Architecture
Description	Partitioning-defective 3 homolog B (PAR3-beta) (Partitioning-defective 3-like protein) (PAR3-L protein) (Amyotrophic lateral sclerosis 2 chromosome region candidate gene 19 protein).

P66B_MOUSE
NC score	0.025046 (rank : 374)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	364	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

FA50A_HUMAN
NC score	0.024807 (rank : 375)	θ value	1.38821 (rank : 185)
Query Neighborhood Hits	364	Target Neighborhood Hits	264	Shared Neighborhood Hits	23
SwissProt Accessions	Q14320, Q5HY37	Gene names	FAM50A, DXS9928E, HXC26, XAP5
Domain Architecture
Description	Protein FAM50A (Protein XAP-5) (Protein HXC-26).

UBP8_MOUSE
NC score	0.024757 (rank : 376)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	364	Target Neighborhood Hits	362	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

EZRI_MOUSE
NC score	0.024732 (rank : 377)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	364	Target Neighborhood Hits	693	Shared Neighborhood Hits	62
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

AKAP1_MOUSE
NC score	0.024708 (rank : 378)	θ value	6.88961 (rank : 309)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

BRE1A_HUMAN
NC score	0.024382 (rank : 379)	θ value	5.27518 (rank : 282)
Query Neighborhood Hits	364	Target Neighborhood Hits	1071	Shared Neighborhood Hits	73
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SFPQ_MOUSE
NC score	0.024027 (rank : 380)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	364	Target Neighborhood Hits	958	Shared Neighborhood Hits	57
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

BRE1A_MOUSE
NC score	0.023826 (rank : 381)	θ value	5.27518 (rank : 283)
Query Neighborhood Hits	364	Target Neighborhood Hits	1025	Shared Neighborhood Hits	72
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CN102_MOUSE
NC score	0.023525 (rank : 382)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC6, Q8R3D7, Q99LT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf102 homolog.

PALB2_HUMAN
NC score	0.023473 (rank : 383)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	364	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

CCD43_HUMAN
NC score	0.023345 (rank : 384)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	364	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

CCD43_MOUSE
NC score	0.023104 (rank : 385)	θ value	5.27518 (rank : 286)
Query Neighborhood Hits	364	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CR29, Q6PDT2	Gene names	Ccdc43, D11Ertd707e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

EFHC2_HUMAN
NC score	0.023096 (rank : 386)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	364	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JST6, Q5JST8, Q68DK4, Q8NEI0, Q9H653	Gene names	EFHC2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member C2.

MERL_MOUSE
NC score	0.022724 (rank : 387)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	364	Target Neighborhood Hits	524	Shared Neighborhood Hits	57
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.022685 (rank : 388)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	364	Target Neighborhood Hits	532	Shared Neighborhood Hits	55
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

TCAL6_HUMAN
NC score	0.022590 (rank : 389)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	364	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

GAGB1_HUMAN
NC score	0.022472 (rank : 390)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	364	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	O75459, Q6FGM3, Q9BSS7	Gene names	PAGE1, GAGE9, GAGEB1
Domain Architecture
Description	G antigen family B member 1 (Prostate-associated gene 1 protein) (PAGE-1) (GAGE-9) (AL5).

PRP4B_MOUSE
NC score	0.021789 (rank : 391)	θ value	0.365318 (rank : 126)
Query Neighborhood Hits	364	Target Neighborhood Hits	1040	Shared Neighborhood Hits	66
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

DDX21_MOUSE
NC score	0.021787 (rank : 392)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	364	Target Neighborhood Hits	350	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ZN291_HUMAN
NC score	0.021682 (rank : 393)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	364	Target Neighborhood Hits	647	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

DPOLZ_MOUSE
NC score	0.020992 (rank : 394)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	364	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

ATRIP_MOUSE
NC score	0.020926 (rank : 395)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	364	Target Neighborhood Hits	248	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMG1	Gene names	Atrip
Domain Architecture	No domain graphic available
Description	ATR-interacting protein (ATM and Rad3-related-interacting protein).

MICA1_HUMAN
NC score	0.020651 (rank : 396)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	364	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDZ2, Q7Z633, Q8IVS9, Q96G47, Q9H6X6, Q9H7I0, Q9HAA1, Q9UFF7	Gene names	MICAL1, MICAL, NICAL
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

TITIN_HUMAN
NC score	0.020629 (rank : 397)	θ value	0.125558 (rank : 99)
Query Neighborhood Hits	364	Target Neighborhood Hits	2923	Shared Neighborhood Hits	161
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CKAP4_MOUSE
NC score	0.020158 (rank : 398)	θ value	5.27518 (rank : 288)
Query Neighborhood Hits	364	Target Neighborhood Hits	596	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DHX16_HUMAN
NC score	0.020028 (rank : 399)	θ value	5.27518 (rank : 290)
Query Neighborhood Hits	364	Target Neighborhood Hits	356	Shared Neighborhood Hits	54
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

SLK_MOUSE
NC score	0.019997 (rank : 400)	θ value	0.125558 (rank : 98)
Query Neighborhood Hits	364	Target Neighborhood Hits	1798	Shared Neighborhood Hits	136
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

CEBPZ_MOUSE
NC score	0.019920 (rank : 401)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	364	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P53569, Q3TXW5, Q3TYA8, Q3UWQ7	Gene names	Cebpz, Cbf2, Cebpa-rs1
Domain Architecture
Description	CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CCAAT-binding factor) (CBF).

FA50B_HUMAN
NC score	0.019760 (rank : 402)	θ value	5.27518 (rank : 292)
Query Neighborhood Hits	364	Target Neighborhood Hits	130	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y247	Gene names	FAM50B, X5L
Domain Architecture
Description	Protein FAM50B (XAP-5-like protein).

CCP2_MOUSE
NC score	0.019456 (rank : 403)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	364	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHG2	Gene names	Dscr1l1
Domain Architecture
Description	Calcipressin-2 (Down syndrome candidate region 1-like protein 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2).

PRP4B_HUMAN
NC score	0.019416 (rank : 404)	θ value	1.06291 (rank : 176)
Query Neighborhood Hits	364	Target Neighborhood Hits	1030	Shared Neighborhood Hits	64
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

ACRBP_HUMAN
NC score	0.019248 (rank : 405)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	364	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

CIP4_HUMAN
NC score	0.018012 (rank : 406)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	364	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

SLK_HUMAN
NC score	0.017704 (rank : 407)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	364	Target Neighborhood Hits	1775	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TULP1_HUMAN
NC score	0.016908 (rank : 408)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	364	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	O00294, O43536	Gene names	TULP1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

PDZK4_MOUSE
NC score	0.016690 (rank : 409)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	364	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QY39, Q6PHP2	Gene names	Pdzk4, Pdzrn4l, Xlu
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein).

ST18_MOUSE
NC score	0.016463 (rank : 410)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	364	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

HDAC5_MOUSE
NC score	0.016298 (rank : 411)	θ value	0.813845 (rank : 155)
Query Neighborhood Hits	364	Target Neighborhood Hits	310	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

DAAM1_MOUSE
NC score	0.016247 (rank : 412)	θ value	4.03905 (rank : 263)
Query Neighborhood Hits	364	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

GP156_HUMAN
NC score	0.015890 (rank : 413)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

TNAP2_HUMAN
NC score	0.015829 (rank : 414)	θ value	2.36792 (rank : 231)
Query Neighborhood Hits	364	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q03169, Q86VI0	Gene names	TNFAIP2
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 2 (Primary response gene B94 protein).

HS90A_MOUSE
NC score	0.014779 (rank : 415)	θ value	1.81305 (rank : 204)
Query Neighborhood Hits	364	Target Neighborhood Hits	155	Shared Neighborhood Hits	23
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

BORG4_HUMAN
NC score	0.014622 (rank : 416)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	364	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

DAAM1_HUMAN
NC score	0.014371 (rank : 417)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	364	Target Neighborhood Hits	483	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

TF3C1_HUMAN
NC score	0.014318 (rank : 418)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	364	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

M4K4_MOUSE
NC score	0.013839 (rank : 419)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	364	Target Neighborhood Hits	1560	Shared Neighborhood Hits	92
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SELS_MOUSE
NC score	0.013650 (rank : 420)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

NEC1_HUMAN
NC score	0.013631 (rank : 421)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	364	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

ANK3_HUMAN
NC score	0.013591 (rank : 422)	θ value	5.27518 (rank : 280)
Query Neighborhood Hits	364	Target Neighborhood Hits	853	Shared Neighborhood Hits	85
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

DNL3_HUMAN
NC score	0.013566 (rank : 423)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	364	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

CD2L2_HUMAN
NC score	0.013471 (rank : 424)	θ value	0.163984 (rank : 100)
Query Neighborhood Hits	364	Target Neighborhood Hits	1439	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

TMC2_HUMAN
NC score	0.013376 (rank : 425)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	364	Target Neighborhood Hits	149	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

SAKS1_MOUSE
NC score	0.013282 (rank : 426)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	364	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

M4K4_HUMAN
NC score	0.012794 (rank : 427)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	364	Target Neighborhood Hits	1589	Shared Neighborhood Hits	85
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

COIA1_MOUSE
NC score	0.012579 (rank : 428)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	364	Target Neighborhood Hits	481	Shared Neighborhood Hits	30
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

NGAP_HUMAN
NC score	0.012400 (rank : 429)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	364	Target Neighborhood Hits	517	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

IRX5_HUMAN
NC score	0.012359 (rank : 430)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	364	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

AT2B1_HUMAN
NC score	0.012234 (rank : 431)	θ value	0.0961366 (rank : 85)
Query Neighborhood Hits	364	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P20020, Q12992, Q12993, Q13819, Q13820, Q13821, Q16504, Q93082	Gene names	ATP2B1, PMCA1
Domain Architecture
Description	Plasma membrane calcium-transporting ATPase 1 (EC 3.6.3.8) (PMCA1) (Plasma membrane calcium pump isoform 1) (Plasma membrane calcium ATPase isoform 1).

MINK1_HUMAN
NC score	0.012208 (rank : 432)	θ value	0.365318 (rank : 124)
Query Neighborhood Hits	364	Target Neighborhood Hits	1477	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SYP2L_MOUSE
NC score	0.012208 (rank : 433)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	364	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BWB1	Gene names	Synpo2l
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

RHBD1_HUMAN
NC score	0.011984 (rank : 434)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	364	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	O75783, Q9NQ85	Gene names	RHBDL1, RHBDL
Domain Architecture
Description	Rhomboid-related protein 1 (EC 3.4.21.105) (RRP) (Rhomboid-like protein 1).

ADDA_HUMAN
NC score	0.011889 (rank : 435)	θ value	5.27518 (rank : 278)
Query Neighborhood Hits	364	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P35611, Q13734, Q14729, Q16156, Q9UJB6	Gene names	ADD1, ADDA
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

LRP3_HUMAN
NC score	0.011499 (rank : 436)	θ value	0.365318 (rank : 123)
Query Neighborhood Hits	364	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CD2L1_MOUSE
NC score	0.011490 (rank : 437)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	364	Target Neighborhood Hits	1463	Shared Neighborhood Hits	86
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

AKP8L_HUMAN
NC score	0.011251 (rank : 438)	θ value	5.27518 (rank : 279)
Query Neighborhood Hits	364	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULX6, O94792, Q96J58, Q9NRQ0, Q9UGM0	Gene names	AKAP8L, NAKAP95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95) (Homologous to AKAP95 protein) (HA95) (Helicase A-binding protein 95) (HAP95).

MINK1_MOUSE
NC score	0.011182 (rank : 439)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	364	Target Neighborhood Hits	1451	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

SKIV2_HUMAN
NC score	0.010941 (rank : 440)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	364	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

PTN23_MOUSE
NC score	0.010737 (rank : 441)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	364	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CI082_MOUSE
NC score	0.010731 (rank : 442)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	364	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

CD2L1_HUMAN
NC score	0.010668 (rank : 443)	θ value	5.27518 (rank : 287)
Query Neighborhood Hits	364	Target Neighborhood Hits	1467	Shared Neighborhood Hits	84
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

GRIP2_HUMAN
NC score	0.010529 (rank : 444)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	364	Target Neighborhood Hits	256	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

PKHA4_MOUSE
NC score	0.010421 (rank : 445)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	364	Target Neighborhood Hits	202	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

UBP35_HUMAN
NC score	0.010275 (rank : 446)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	364	Target Neighborhood Hits	223	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

CNGA1_MOUSE
NC score	0.010214 (rank : 447)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	364	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

IRX3_HUMAN
NC score	0.009877 (rank : 448)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	364	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

LYST_HUMAN
NC score	0.009650 (rank : 449)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	364	Target Neighborhood Hits	324	Shared Neighborhood Hits	27
SwissProt Accessions	Q99698, O43274, Q5T2U9, Q96TD7, Q96TD8, Q99709, Q9H133	Gene names	LYST, CHS, CHS1
Domain Architecture
Description	Lysosomal-trafficking regulator (Beige homolog).

ZDHC8_HUMAN
NC score	0.009569 (rank : 450)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	364	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

DNJC1_MOUSE
NC score	0.008817 (rank : 451)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	364	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q61712	Gene names	Dnajc1, Dnajl1, Mtj1
Domain Architecture
Description	DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).

ANKY2_HUMAN
NC score	0.008683 (rank : 452)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	364	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

RD23A_MOUSE
NC score	0.008420 (rank : 453)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	P54726	Gene names	Rad23a, Mhr23a
Domain Architecture
Description	UV excision repair protein RAD23 homolog A (mHR23A).

STML1_HUMAN
NC score	0.008056 (rank : 454)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	364	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

MBTP1_HUMAN
NC score	0.007996 (rank : 455)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

CNGA1_HUMAN
NC score	0.007650 (rank : 456)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	364	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

DDX55_MOUSE
NC score	0.007625 (rank : 457)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	364	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

ZEP1_MOUSE
NC score	0.007340 (rank : 458)	θ value	2.36792 (rank : 233)
Query Neighborhood Hits	364	Target Neighborhood Hits	1063	Shared Neighborhood Hits	50
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

TAB1_MOUSE
NC score	0.007113 (rank : 459)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	364	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CF89, Q7TQJ5, Q80V65, Q8R0D1	Gene names	Map3k7ip1, Tab1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1).

LAP4_MOUSE
NC score	0.006860 (rank : 460)	θ value	1.38821 (rank : 188)
Query Neighborhood Hits	364	Target Neighborhood Hits	590	Shared Neighborhood Hits	30
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

M3K14_MOUSE
NC score	0.006742 (rank : 461)	θ value	0.47712 (rank : 135)
Query Neighborhood Hits	364	Target Neighborhood Hits	889	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

IBP4_HUMAN
NC score	0.006245 (rank : 462)	θ value	5.27518 (rank : 293)
Query Neighborhood Hits	364	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

CAC1E_HUMAN
NC score	0.006198 (rank : 463)	θ value	6.88961 (rank : 311)
Query Neighborhood Hits	364	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

RBM19_MOUSE
NC score	0.006113 (rank : 464)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	364	Target Neighborhood Hits	296	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

ARHGC_MOUSE
NC score	0.006063 (rank : 465)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	364	Target Neighborhood Hits	344	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CAC1E_MOUSE
NC score	0.005833 (rank : 466)	θ value	6.88961 (rank : 312)
Query Neighborhood Hits	364	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

VINEX_MOUSE
NC score	0.005723 (rank : 467)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	364	Target Neighborhood Hits	286	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

MYPT1_MOUSE
NC score	0.005592 (rank : 468)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	364	Target Neighborhood Hits	539	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

SEP11_MOUSE
NC score	0.005421 (rank : 469)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	364	Target Neighborhood Hits	300	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C1B7, Q6P2K5, Q6P6I0	Gene names	Sept11, D5Ertd606e
Domain Architecture	No domain graphic available
Description	Septin-11.

GDF5_HUMAN
NC score	0.005395 (rank : 470)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	364	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	P43026, Q96SB1	Gene names	GDF5, CDMP1
Domain Architecture
Description	Growth/differentiation factor 5 precursor (GDF-5) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Radotermin).

PKDRE_MOUSE
NC score	0.004977 (rank : 471)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	364	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

CNTN1_MOUSE
NC score	0.004601 (rank : 472)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	364	Target Neighborhood Hits	422	Shared Neighborhood Hits	4
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

ACK1_MOUSE
NC score	0.004315 (rank : 473)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	364	Target Neighborhood Hits	1080	Shared Neighborhood Hits	47
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ITPR1_HUMAN
NC score	0.004169 (rank : 474)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	364	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ACK1_HUMAN
NC score	0.003649 (rank : 475)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	364	Target Neighborhood Hits	1140	Shared Neighborhood Hits	57
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

NEK4_HUMAN
NC score	0.003649 (rank : 476)	θ value	0.47712 (rank : 136)
Query Neighborhood Hits	364	Target Neighborhood Hits	883	Shared Neighborhood Hits	24
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

LAP2_MOUSE
NC score	0.003648 (rank : 477)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	364	Target Neighborhood Hits	482	Shared Neighborhood Hits	20
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

LAP2_HUMAN
NC score	0.003457 (rank : 478)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	364	Target Neighborhood Hits	499	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

DCAK3_HUMAN
NC score	0.003137 (rank : 479)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	364	Target Neighborhood Hits	888	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C098	Gene names	DCAMKL3, KIAA1765
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3).

TRPC2_MOUSE
NC score	0.002673 (rank : 480)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	364	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

CNTN1_HUMAN
NC score	0.002663 (rank : 481)	θ value	5.27518 (rank : 289)
Query Neighborhood Hits	364	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

NEK3_MOUSE
NC score	0.000855 (rank : 482)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	364	Target Neighborhood Hits	854	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

ZBT38_HUMAN
NC score	-0.001834 (rank : 483)	θ value	0.0961366 (rank : 91)
Query Neighborhood Hits	364	Target Neighborhood Hits	885	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ZSCA1_HUMAN
NC score	-0.002825 (rank : 484)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	364	Target Neighborhood Hits	724	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

ZBTB9_MOUSE
NC score	-0.003638 (rank : 485)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	364	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZN206_HUMAN
NC score	-0.005973 (rank : 486)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	364	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q96SZ4	Gene names	ZNF206, ZSCAN10
Domain Architecture	No domain graphic available
Description	Zinc finger protein 206 (Zinc finger and SCAN domain-containing protein 10).

PRD10_HUMAN
NC score	-0.006417 (rank : 487)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	364	Target Neighborhood Hits	769	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQV6, Q9ULI9	Gene names	PRDM10, KIAA1231, PFM7
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 10 (PR domain-containing protein 10).

ZN434_HUMAN
NC score	-0.006450 (rank : 488)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	364	Target Neighborhood Hits	747	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NX65, Q7Z6G2	Gene names	ZNF434
Domain Architecture
Description	Zinc finger protein 434.