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Network neighborhood for query Sequence : BTAF1_HUMAN

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BTAF1_HUMAN
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BTAF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

ERCC6_HUMAN
θ value	4.36332e-79 (rank : 2)	NC score	0.944390 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA2_HUMAN
θ value	3.4653e-68 (rank : 3)	NC score	0.892848 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	503	Shared Neighborhood Hits	44
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA1_MOUSE
θ value	6.53529e-67 (rank : 4)	NC score	0.938595 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA5_MOUSE
θ value	1.11475e-66 (rank : 5)	NC score	0.942353 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
θ value	2.4834e-66 (rank : 6)	NC score	0.942275 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA1_HUMAN
θ value	6.11685e-65 (rank : 7)	NC score	0.940822 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA4_HUMAN
θ value	2.56992e-63 (rank : 8)	NC score	0.879239 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	597	Shared Neighborhood Hits	45
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD1_HUMAN
θ value	4.38363e-63 (rank : 9)	NC score	0.911676 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	42
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMRCD_HUMAN
θ value	2.17557e-62 (rank : 10)	NC score	0.944614 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD1_MOUSE
θ value	4.84666e-62 (rank : 11)	NC score	0.915564 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	266	Shared Neighborhood Hits	42
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	6.99855e-61 (rank : 12)	NC score	0.915704 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

RA54B_HUMAN
θ value	1.01059e-59 (rank : 13)	NC score	0.942470 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMRCD_MOUSE
θ value	2.7521e-57 (rank : 14)	NC score	0.942626 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RAD54_HUMAN
θ value	4.69435e-57 (rank : 15)	NC score	0.939818 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	1.78386e-56 (rank : 16)	NC score	0.938409 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD6_HUMAN
θ value	6.77864e-56 (rank : 17)	NC score	0.908691 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	342	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	7.49467e-55 (rank : 18)	NC score	0.915195 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

RA54B_MOUSE
θ value	2.18062e-54 (rank : 19)	NC score	0.939499 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD9_HUMAN
θ value	1.41344e-53 (rank : 20)	NC score	0.903061 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	38
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	4.11246e-53 (rank : 21)	NC score	0.898366 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	427	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD4_HUMAN
θ value	8.30557e-46 (rank : 22)	NC score	0.840771 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	365	Shared Neighborhood Hits	43
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	8.30557e-46 (rank : 23)	NC score	0.837271 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	408	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	7.77379e-44 (rank : 24)	NC score	0.839759 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	2.26182e-43 (rank : 25)	NC score	0.841811 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

INOC1_HUMAN
θ value	8.04462e-41 (rank : 26)	NC score	0.899470 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	1.05066e-40 (rank : 27)	NC score	0.899749 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

TTF2_HUMAN
θ value	1.12514e-34 (rank : 28)	NC score	0.873290 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	7.06379e-29 (rank : 29)	NC score	0.825131 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	364	Shared Neighborhood Hits	40
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMAL1_HUMAN
θ value	5.97985e-28 (rank : 30)	NC score	0.840225 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	174	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	7.80994e-28 (rank : 31)	NC score	0.849805 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

EP400_HUMAN
θ value	5.06226e-27 (rank : 32)	NC score	0.805152 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	2.12685e-25 (rank : 33)	NC score	0.796713 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SMRA3_MOUSE
θ value	3.88503e-19 (rank : 34)	NC score	0.738742 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	267	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

ATRX_MOUSE
θ value	7.32683e-18 (rank : 35)	NC score	0.692981 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SMRA3_HUMAN
θ value	7.32683e-18 (rank : 36)	NC score	0.734482 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ATRX_HUMAN
θ value	1.63225e-17 (rank : 37)	NC score	0.673130 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	842	Shared Neighborhood Hits	45
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

FANCM_MOUSE
θ value	0.0252991 (rank : 38)	NC score	0.064693 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DDX28_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.041483 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	103	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

FANCM_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.072691 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

TNPO3_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.025016 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P2B1, Q7TSL6, Q8BKX4, Q8BP42	Gene names	Tnpo3
Domain Architecture	No domain graphic available
Description	Transportin-3.

BMS1_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.033447 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

DD19A_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.030700 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19A_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.030730 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.030645 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

FYCO1_MOUSE
θ value	0.47712 (rank : 46)	NC score	0.003354 (rank : 140)
Query Neighborhood Hits	97	Target Neighborhood Hits	1059	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

TNPO2_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.035835 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.035904 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

GPTC8_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.030656 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

K0423_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.027958 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

HIRP3_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.063592 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	323	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

GRP75_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.010106 (rank : 123)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

K0423_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.025049 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

SYCP2_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.040737 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

CTGE6_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.004644 (rank : 137)
Query Neighborhood Hits	97	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

PPIG_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.027096 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	670	Shared Neighborhood Hits	19
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TNPO1_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.032968 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.033003 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

VPS54_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.015724 (rank : 111)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

ZC3H8_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.017846 (rank : 106)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

BAG3_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.016501 (rank : 110)
Query Neighborhood Hits	97	Target Neighborhood Hits	314	Shared Neighborhood Hits	5
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

IMB1_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.024337 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

RNBP6_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.017025 (rank : 107)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

TLK2_MOUSE
θ value	2.36792 (rank : 64)	NC score	-0.001900 (rank : 143)
Query Neighborhood Hits	97	Target Neighborhood Hits	1088	Shared Neighborhood Hits	6
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).

GCN1L_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.018256 (rank : 105)
Query Neighborhood Hits	97	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

GRP75_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.008345 (rank : 126)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

DNMT1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.027913 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

JHD2B_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.006174 (rank : 134)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

DMAP1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.015303 (rank : 113)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

DMAP1_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.015319 (rank : 112)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

HD_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.008257 (rank : 127)
Query Neighborhood Hits	97	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

K1H1_HUMAN
θ value	5.27518 (rank : 72)	NC score	-0.000265 (rank : 141)
Query Neighborhood Hits	97	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

MY18A_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.012061 (rank : 118)
Query Neighborhood Hits	97	Target Neighborhood Hits	1929	Shared Neighborhood Hits	28
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

UTP20_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.013196 (rank : 115)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

UTP20_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.013167 (rank : 116)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

XPO1_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.016575 (rank : 109)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	O14980, Q63HP8, Q68CP3, Q99433	Gene names	XPO1, CRM1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

XPO1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.016872 (rank : 108)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5F9	Gene names	Xpo1, Crm1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

2AAA_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.011135 (rank : 122)
Query Neighborhood Hits	97	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.011416 (rank : 120)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

ACY1_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.013234 (rank : 114)
Query Neighborhood Hits	97	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q03154	Gene names	ACY1
Domain Architecture
Description	Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1).

AFAD_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.004104 (rank : 138)
Query Neighborhood Hits	97	Target Neighborhood Hits	689	Shared Neighborhood Hits	5
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CTND2_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.006109 (rank : 135)
Query Neighborhood Hits	97	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

GOSR1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.010051 (rank : 124)
Query Neighborhood Hits	97	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O95249, O75392	Gene names	GOSR1, GS28
Domain Architecture
Description	Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28).

IFT20_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.012999 (rank : 117)
Query Neighborhood Hits	97	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY31, Q5GLZ2, Q9BUG5	Gene names	IFT20
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 20 homolog (Intraflagellar transport protein 20) (hIFT20).

IPO11_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.011403 (rank : 121)
Query Neighborhood Hits	97	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

RU2B_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.006727 (rank : 132)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P08579, Q9UJD4	Gene names	SNRPB2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein B''.

TAD3L_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.007264 (rank : 131)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

WFDC8_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.007512 (rank : 129)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

ZC3H8_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.011514 (rank : 119)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

BAG3_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.024015 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	513	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CI072_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.007443 (rank : 130)
Query Neighborhood Hits	97	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DFW0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf72 homolog.

DBF4_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.006720 (rank : 133)
Query Neighborhood Hits	97	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

ECM29_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.009697 (rank : 125)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

STX7_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.003966 (rank : 139)
Query Neighborhood Hits	97	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	O15400, Q5SZW2, Q96ES9	Gene names	STX7
Domain Architecture
Description	Syntaxin-7.

TIP60_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.004763 (rank : 136)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TLK2_HUMAN
θ value	8.99809 (rank : 96)	NC score	-0.001213 (rank : 142)
Query Neighborhood Hits	97	Target Neighborhood Hits	1044	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

XPO5_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.008066 (rank : 128)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HAV4, Q5JTE6, Q96G48, Q96HN3, Q9BWM6, Q9BZV5, Q9H9M4, Q9NT89, Q9NW39, Q9ULC9	Gene names	XPO5, KIAA1291, RANBP21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

AIRE_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.085126 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.086417 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.063434 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	693	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.060653 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	701	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.068660 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BPTF_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.081972 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	786	Shared Neighborhood Hits	19
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.063452 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.063452 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.053983 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.056985 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.075864 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.067519 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX7_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.055431 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.058837 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

IWS1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.061433 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.066270 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	1258	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.058782 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.061270 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.059234 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

NIPBL_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.059409 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.054483 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.051869 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	427	Shared Neighborhood Hits	9
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.054748 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.054890 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PF21A_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.072352 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.073127 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.074617 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.075138 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	278	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.080697 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.080687 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.077731 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	488	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RBBP6_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.051949 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	1135	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052596 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	1014	Shared Neighborhood Hits	27
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RSF1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.065318 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.066185 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TCAL5_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.050544 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	806	Shared Neighborhood Hits	21
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.066085 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	1037	Shared Neighborhood Hits	21
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1A_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.059436 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.062356 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.055023 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	410	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.061794 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	498	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.062023 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.061313 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.051590 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZMY11_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.072853 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.070685 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

BTAF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMRCD_HUMAN
NC score	0.944614 (rank : 2)	θ value	2.17557e-62 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

ERCC6_HUMAN
NC score	0.944390 (rank : 3)	θ value	4.36332e-79 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	247	Shared Neighborhood Hits	41
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMRCD_MOUSE
NC score	0.942626 (rank : 4)	θ value	2.7521e-57 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

RA54B_HUMAN
NC score	0.942470 (rank : 5)	θ value	1.01059e-59 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA5_MOUSE
NC score	0.942353 (rank : 6)	θ value	1.11475e-66 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.942275 (rank : 7)	θ value	2.4834e-66 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA1_HUMAN
NC score	0.940822 (rank : 8)	θ value	6.11685e-65 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

RAD54_HUMAN
NC score	0.939818 (rank : 9)	θ value	4.69435e-57 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RA54B_MOUSE
NC score	0.939499 (rank : 10)	θ value	2.18062e-54 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA1_MOUSE
NC score	0.938595 (rank : 11)	θ value	6.53529e-67 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

RAD54_MOUSE
NC score	0.938409 (rank : 12)	θ value	1.78386e-56 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

CHD2_HUMAN
NC score	0.915704 (rank : 13)	θ value	6.99855e-61 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	360	Shared Neighborhood Hits	44
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_MOUSE
NC score	0.915564 (rank : 14)	θ value	4.84666e-62 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	266	Shared Neighborhood Hits	42
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
NC score	0.915195 (rank : 15)	θ value	7.49467e-55 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	235	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_HUMAN
NC score	0.911676 (rank : 16)	θ value	4.38363e-63 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	337	Shared Neighborhood Hits	42
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
NC score	0.908691 (rank : 17)	θ value	6.77864e-56 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	342	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_HUMAN
NC score	0.903061 (rank : 18)	θ value	1.41344e-53 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	38
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

INOC1_MOUSE
NC score	0.899749 (rank : 19)	θ value	1.05066e-40 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.899470 (rank : 20)	θ value	8.04462e-41 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	181	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

CHD9_MOUSE
NC score	0.898366 (rank : 21)	θ value	4.11246e-53 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	427	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMCA2_HUMAN
NC score	0.892848 (rank : 22)	θ value	3.4653e-68 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	503	Shared Neighborhood Hits	44
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.879239 (rank : 23)	θ value	2.56992e-63 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	597	Shared Neighborhood Hits	45
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TTF2_HUMAN
NC score	0.873290 (rank : 24)	θ value	1.12514e-34 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

SMAL1_MOUSE
NC score	0.849805 (rank : 25)	θ value	7.80994e-28 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	157	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

CHD3_HUMAN
NC score	0.841811 (rank : 26)	θ value	2.26182e-43 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	397	Shared Neighborhood Hits	43
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.840771 (rank : 27)	θ value	8.30557e-46 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	365	Shared Neighborhood Hits	43
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

SMAL1_HUMAN
NC score	0.840225 (rank : 28)	θ value	5.97985e-28 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	174	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

CHD5_HUMAN
NC score	0.839759 (rank : 29)	θ value	7.77379e-44 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	349	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.837271 (rank : 30)	θ value	8.30557e-46 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	408	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

TTF2_MOUSE
NC score	0.825131 (rank : 31)	θ value	7.06379e-29 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	364	Shared Neighborhood Hits	40
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

EP400_HUMAN
NC score	0.805152 (rank : 32)	θ value	5.06226e-27 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	556	Shared Neighborhood Hits	41
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.796713 (rank : 33)	θ value	2.12685e-25 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SMRA3_MOUSE
NC score	0.738742 (rank : 34)	θ value	3.88503e-19 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	267	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.734482 (rank : 35)	θ value	7.32683e-18 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	265	Shared Neighborhood Hits	37
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ATRX_MOUSE
NC score	0.692981 (rank : 36)	θ value	7.32683e-18 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.673130 (rank : 37)	θ value	1.63225e-17 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	842	Shared Neighborhood Hits	45
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

AIRE_MOUSE
NC score	0.086417 (rank : 38)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	196	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.085126 (rank : 39)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

BPTF_HUMAN
NC score	0.081972 (rank : 40)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	786	Shared Neighborhood Hits	19
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PHF12_HUMAN
NC score	0.080697 (rank : 41)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	97	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.080687 (rank : 42)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	97	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
NC score	0.077731 (rank : 43)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	97	Target Neighborhood Hits	488	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

CBX5_HUMAN
NC score	0.075864 (rank : 44)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	12
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

PF21B_MOUSE
NC score	0.075138 (rank : 45)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	97	Target Neighborhood Hits	278	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_HUMAN
NC score	0.074617 (rank : 46)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	97	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21A_MOUSE
NC score	0.073127 (rank : 47)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	97	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ZMY11_HUMAN
NC score	0.072853 (rank : 48)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	97	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

FANCM_HUMAN
NC score	0.072691 (rank : 49)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	210	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

PF21A_HUMAN
NC score	0.072352 (rank : 50)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	97	Target Neighborhood Hits	303	Shared Neighborhood Hits	8
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

ZMY11_MOUSE
NC score	0.070685 (rank : 51)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	97	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ1B_MOUSE
NC score	0.068660 (rank : 52)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CBX5_MOUSE
NC score	0.067519 (rank : 53)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

IWS1_MOUSE
NC score	0.066270 (rank : 54)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	97	Target Neighborhood Hits	1258	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SP110_HUMAN
NC score	0.066185 (rank : 55)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	97	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TGON2_HUMAN
NC score	0.066085 (rank : 56)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	97	Target Neighborhood Hits	1037	Shared Neighborhood Hits	21
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RSF1_HUMAN
NC score	0.065318 (rank : 57)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	97	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

FANCM_MOUSE
NC score	0.064693 (rank : 58)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HIRP3_HUMAN
NC score	0.063592 (rank : 59)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	323	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

CBX1_HUMAN
NC score	0.063452 (rank : 60)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.063452 (rank : 61)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

BAZ1A_HUMAN
NC score	0.063434 (rank : 62)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	693	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

TIF1A_MOUSE
NC score	0.062356 (rank : 63)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	9
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI66_HUMAN
NC score	0.062023 (rank : 64)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	97	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_MOUSE
NC score	0.061794 (rank : 65)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	97	Target Neighborhood Hits	498	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

IWS1_HUMAN
NC score	0.061433 (rank : 66)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	97	Target Neighborhood Hits	1241	Shared Neighborhood Hits	28
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRI66_MOUSE
NC score	0.061313 (rank : 67)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

LEO1_MOUSE
NC score	0.061270 (rank : 68)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	97	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

BAZ1B_HUMAN
NC score	0.060653 (rank : 69)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	701	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

TIF1A_HUMAN
NC score	0.059436 (rank : 70)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	97	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

NIPBL_HUMAN
NC score	0.059409 (rank : 71)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	97	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

LY10_HUMAN
NC score	0.059234 (rank : 72)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	97	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

CBX7_MOUSE
NC score	0.058837 (rank : 73)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	97	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

LEO1_HUMAN
NC score	0.058782 (rank : 74)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	97	Target Neighborhood Hits	958	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CBX3_MOUSE
NC score	0.056985 (rank : 75)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	97	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX7_HUMAN
NC score	0.055431 (rank : 76)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	97	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

TIF1G_HUMAN
NC score	0.055023 (rank : 77)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	97	Target Neighborhood Hits	410	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

PB1_HUMAN
NC score	0.054890 (rank : 78)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	97	Target Neighborhood Hits	261	Shared Neighborhood Hits	4
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

NSD1_MOUSE
NC score	0.054748 (rank : 79)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	97	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NPBL_MOUSE
NC score	0.054483 (rank : 80)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	97	Target Neighborhood Hits	1041	Shared Neighborhood Hits	22
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CBX3_HUMAN
NC score	0.053983 (rank : 81)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

RBBP6_MOUSE
NC score	0.052596 (rank : 82)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	97	Target Neighborhood Hits	1014	Shared Neighborhood Hits	27
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBBP6_HUMAN
NC score	0.051949 (rank : 83)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	97	Target Neighborhood Hits	1135	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

NSD1_HUMAN
NC score	0.051869 (rank : 84)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	97	Target Neighborhood Hits	427	Shared Neighborhood Hits	9
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TXND2_MOUSE
NC score	0.051590 (rank : 85)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	97	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TCAL5_HUMAN
NC score	0.050544 (rank : 86)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	97	Target Neighborhood Hits	806	Shared Neighborhood Hits	21
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

DDX28_HUMAN
NC score	0.041483 (rank : 87)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	103	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

SYCP2_HUMAN
NC score	0.040737 (rank : 88)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TNPO2_MOUSE
NC score	0.035904 (rank : 89)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.035835 (rank : 90)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

BMS1_HUMAN
NC score	0.033447 (rank : 91)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

TNPO1_MOUSE
NC score	0.033003 (rank : 92)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.032968 (rank : 93)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

DD19A_MOUSE
NC score	0.030730 (rank : 94)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19A_HUMAN
NC score	0.030700 (rank : 95)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

GPTC8_HUMAN
NC score	0.030656 (rank : 96)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	366	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

DD19B_HUMAN
NC score	0.030645 (rank : 97)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

K0423_MOUSE
NC score	0.027958 (rank : 98)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

DNMT1_HUMAN
NC score	0.027913 (rank : 99)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

PPIG_HUMAN
NC score	0.027096 (rank : 100)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	670	Shared Neighborhood Hits	19
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

K0423_HUMAN
NC score	0.025049 (rank : 101)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TNPO3_MOUSE
NC score	0.025016 (rank : 102)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P2B1, Q7TSL6, Q8BKX4, Q8BP42	Gene names	Tnpo3
Domain Architecture	No domain graphic available
Description	Transportin-3.

IMB1_HUMAN
NC score	0.024337 (rank : 103)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

BAG3_MOUSE
NC score	0.024015 (rank : 104)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	513	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

GCN1L_HUMAN
NC score	0.018256 (rank : 105)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

ZC3H8_HUMAN
NC score	0.017846 (rank : 106)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N5P1, Q9BZ75	Gene names	ZC3H8, ZC3HDC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8.

RNBP6_HUMAN
NC score	0.017025 (rank : 107)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

XPO1_MOUSE
NC score	0.016872 (rank : 108)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P5F9	Gene names	Xpo1, Crm1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

XPO1_HUMAN
NC score	0.016575 (rank : 109)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	9
SwissProt Accessions	O14980, Q63HP8, Q68CP3, Q99433	Gene names	XPO1, CRM1
Domain Architecture	No domain graphic available
Description	Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog).

BAG3_HUMAN
NC score	0.016501 (rank : 110)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	314	Shared Neighborhood Hits	5
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

VPS54_HUMAN
NC score	0.015724 (rank : 111)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P1Q0, Q5VIR5, Q86YF7, Q8N6G3, Q9NPV0, Q9NT07, Q9NUJ0	Gene names	VPS54, HCC8
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 54 (Tumor antigen SLP-8p) (Hepatocellular carcinoma protein 8).

DMAP1_MOUSE
NC score	0.015319 (rank : 112)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI44, Q99LM0, Q9CSS9, Q9DB33	Gene names	Dmap1, Mmtr
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1) (MAT1-mediated transcriptional repressor).

DMAP1_HUMAN
NC score	0.015303 (rank : 113)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPF5, Q5TG41, Q7Z3H7, Q9H0S8, Q9P2C2	Gene names	DMAP1, KIAA1425
Domain Architecture
Description	DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1) (DNMAP1).

ACY1_HUMAN
NC score	0.013234 (rank : 114)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q03154	Gene names	ACY1
Domain Architecture
Description	Aminoacylase-1 (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (ACY-1).

UTP20_HUMAN
NC score	0.013196 (rank : 115)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

UTP20_MOUSE
NC score	0.013167 (rank : 116)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

IFT20_HUMAN
NC score	0.012999 (rank : 117)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IY31, Q5GLZ2, Q9BUG5	Gene names	IFT20
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 20 homolog (Intraflagellar transport protein 20) (hIFT20).

MY18A_HUMAN
NC score	0.012061 (rank : 118)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	1929	Shared Neighborhood Hits	28
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ZC3H8_MOUSE
NC score	0.011514 (rank : 119)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

2AAA_MOUSE
NC score	0.011416 (rank : 120)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

IPO11_MOUSE
NC score	0.011403 (rank : 121)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

2AAA_HUMAN
NC score	0.011135 (rank : 122)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

GRP75_HUMAN
NC score	0.010106 (rank : 123)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

GOSR1_HUMAN
NC score	0.010051 (rank : 124)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O95249, O75392	Gene names	GOSR1, GS28
Domain Architecture
Description	Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28).

ECM29_MOUSE
NC score	0.009697 (rank : 125)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

GRP75_MOUSE
NC score	0.008345 (rank : 126)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HD_HUMAN
NC score	0.008257 (rank : 127)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

XPO5_HUMAN
NC score	0.008066 (rank : 128)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HAV4, Q5JTE6, Q96G48, Q96HN3, Q9BWM6, Q9BZV5, Q9H9M4, Q9NT89, Q9NW39, Q9ULC9	Gene names	XPO5, KIAA1291, RANBP21
Domain Architecture	No domain graphic available
Description	Exportin-5 (Exp5) (Ran-binding protein 21).

WFDC8_HUMAN
NC score	0.007512 (rank : 129)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IUA0, Q5TDV2, Q96A34	Gene names	WFDC8, C20orf170, WAP8
Domain Architecture
Description	WAP four-disulfide core domain protein 8 precursor (Putative protease inhibitor WAP8).

CI072_MOUSE
NC score	0.007443 (rank : 130)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q6DFW0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf72 homolog.

TAD3L_MOUSE
NC score	0.007264 (rank : 131)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

RU2B_HUMAN
NC score	0.006727 (rank : 132)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P08579, Q9UJD4	Gene names	SNRPB2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein B''.

DBF4_HUMAN
NC score	0.006720 (rank : 133)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBU7, O75226, Q75MS6, Q75N01, Q9Y2M6	Gene names	DBF4, ASK
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (Activator of S phase Kinase).

JHD2B_HUMAN
NC score	0.006174 (rank : 134)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	171	Shared Neighborhood Hits	2
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

CTND2_MOUSE
NC score	0.006109 (rank : 135)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	227	Shared Neighborhood Hits	4
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

TIP60_MOUSE
NC score	0.004763 (rank : 136)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

CTGE6_HUMAN
NC score	0.004644 (rank : 137)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	650	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

AFAD_HUMAN
NC score	0.004104 (rank : 138)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	689	Shared Neighborhood Hits	5
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

STX7_HUMAN
NC score	0.003966 (rank : 139)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	O15400, Q5SZW2, Q96ES9	Gene names	STX7
Domain Architecture
Description	Syntaxin-7.

FYCO1_MOUSE
NC score	0.003354 (rank : 140)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	1059	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

K1H1_HUMAN
NC score	-0.000265 (rank : 141)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	433	Shared Neighborhood Hits	5
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

TLK2_HUMAN
NC score	-0.001213 (rank : 142)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	1044	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UE8, Q9UKI7, Q9Y4F7	Gene names	TLK2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2) (PKU-alpha).

TLK2_MOUSE
NC score	-0.001900 (rank : 143)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	1088	Shared Neighborhood Hits	6
SwissProt Accessions	O55047, Q9D5Y5	Gene names	Tlk2
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 2 (EC 2.7.11.1) (Tousled- like kinase 2).