Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : GCN1L_HUMAN

For an explanation of this page, click here

GCN1L_HUMAN
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GCN1L_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

ECM29_HUMAN
θ value	1.38499e-08 (rank : 2)	NC score	0.294421 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

ECM29_MOUSE
θ value	5.26297e-08 (rank : 3)	NC score	0.285792 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

2AAA_MOUSE
θ value	4.45536e-07 (rank : 4)	NC score	0.309525 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
θ value	5.81887e-07 (rank : 5)	NC score	0.308415 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_HUMAN
θ value	1.69304e-06 (rank : 6)	NC score	0.305698 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
θ value	8.40245e-06 (rank : 7)	NC score	0.297839 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

HEAT2_HUMAN
θ value	9.29e-05 (rank : 8)	NC score	0.259549 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

IPO4_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.214496 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
θ value	0.00298849 (rank : 10)	NC score	0.192243 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

CAND1_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.167885 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	0.00509761 (rank : 12)	NC score	0.164898 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

FRAP_MOUSE
θ value	0.00869519 (rank : 13)	NC score	0.114586 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
θ value	0.0148317 (rank : 14)	NC score	0.113080 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	83	Shared Neighborhood Hits	20
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

CAND2_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.162424 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

PLAK_MOUSE
θ value	0.0330416 (rank : 16)	NC score	0.107144 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.107065 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CT2NL_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.068633 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	1059	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

IMA4_HUMAN
θ value	0.0563607 (rank : 19)	NC score	0.084247 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	0.0563607 (rank : 20)	NC score	0.084320 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

SF3B1_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.140631 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.139018 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

AKAP9_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.059686 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	1710	Shared Neighborhood Hits	48
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CLAP1_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.068161 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

MMS19_MOUSE
θ value	0.125558 (rank : 25)	NC score	0.100517 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

CT2NL_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.071639 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RABE1_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.057508 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	1105	Shared Neighborhood Hits	40
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CP135_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.050498 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	1290	Shared Neighborhood Hits	45
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MMS19_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.093505 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T76, Q5T455, Q66K82, Q7L4W8, Q969Z1, Q96DF1, Q96MR1, Q96RK5, Q96SK1, Q9BUE2, Q9BYS9	Gene names	MMS19L, MMS19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (hMMS19) (MET18 homolog).

MOT8_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.041157 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

CAND2_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.155618 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

COG3_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.070897 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JB2, Q5VT70, Q8IXX4, Q9BZ92	Gene names	COG3, SEC34
Domain Architecture
Description	Conserved oligomeric Golgi complex component 3 (Vesicle docking protein SEC34 homolog) (p94).

TNPO1_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.129814 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.129637 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

HMMR_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.049488 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	1178	Shared Neighborhood Hits	38
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA3_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.045506 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

IMA3_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.072266 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.073272 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

RABE1_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.054233 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	1104	Shared Neighborhood Hits	38
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RFIP3_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.049740 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	1055	Shared Neighborhood Hits	38
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

LIPA2_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.039393 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	1282	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

TNPO2_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.119163 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.121874 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

ZFP27_MOUSE
θ value	1.06291 (rank : 44)	NC score	0.000504 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).

BPAEA_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.041209 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	1480	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

COG3_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.063837 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CI04	Gene names	Cog3
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 3.

K0423_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.055842 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

CCD46_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.042281 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CTNB1_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.090194 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.090198 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

HD_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.061707 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

PRR8_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.048340 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

GOGB1_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.041491 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	2297	Shared Neighborhood Hits	54
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HD_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.053938 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

IMB1_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.110166 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB3_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.106375 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.106666 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

NEB2_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.041092 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	883	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PEPL_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.047389 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	1105	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SPAG6_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.076844 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

TRI25_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.019732 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	472	Shared Neighborhood Hits	17
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

AT8A1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.015359 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q0	Gene names	ATP8A1, ATPIA
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

BTAF1_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.018256 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CCD50_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.051730 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CKAP5_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.049635 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

EEA1_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.041804 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	1637	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

KIF23_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.028113 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

LDH6A_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.018524 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMR3	Gene names	LDHAL6A, LDHL2
Domain Architecture	No domain graphic available
Description	L-lactate dehydrogenase A-like 6A (EC 1.1.1.27).

NEB2_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.040904 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	889	Shared Neighborhood Hits	36
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

PFD6_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.058133 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PFD6_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.056148 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

ROCK2_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.020599 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	2073	Shared Neighborhood Hits	50
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

RTN4_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.022236 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

ACINU_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.036263 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	712	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AT8A1_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.014621 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	P70704	Gene names	Atp8a1, Atpc1
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

CP135_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.044876 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	1278	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RASL1_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.012613 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RB6I2_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.041758 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	1584	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.042096 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	1433	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

APOB_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.034217 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

CCD50_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.046303 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

FES_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.002462 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	980	Shared Neighborhood Hits	20
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

GCC2_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.040370 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	1558	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA4_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.039592 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	2034	Shared Neighborhood Hits	47
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

IFT81_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.041705 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	959	Shared Neighborhood Hits	40
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IMB1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.102910 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

MRCKB_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.017618 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	2180	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RBP24_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.040262 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	1559	Shared Neighborhood Hits	45
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SYHH_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.019923 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P49590	Gene names	HARSL, HARSR, HO3
Domain Architecture
Description	Histidyl-tRNA synthetase homolog (EC 6.1.1.21) (Histidine--tRNA ligase homolog) (HisRS).

SYTL4_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.009049 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

ZMYM1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.021367 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SVZ6, Q7Z3Q4	Gene names	ZMYM1
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 1.

CCD46_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.040558 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	1430	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

HMMR_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.045744 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	1082	Shared Neighborhood Hits	43
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IFT81_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.043761 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	893	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

KI13A_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.011608 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

MYO5C_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.026293 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	1206	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NAL11_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.009881 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

RNBP6_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.085216 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

STK36_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.003751 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

ULK4_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.003867 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	793	Shared Neighborhood Hits	10
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

ATR_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.037719 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

B4GT2_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.008690 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2Y2, Q3TMP2	Gene names	B4galt2
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

BFSP1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.027018 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	508	Shared Neighborhood Hits	38
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

MACOI_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.039199 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MYH13_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.028367 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	1504	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.028139 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1478	Shared Neighborhood Hits	47
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PCDGK_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.001515 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN70, O60622, Q08192, Q9Y5C4	Gene names	PCDHGC3, PCDH2
Domain Architecture
Description	Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2).

PHF3_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.017354 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ROCK2_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.020002 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	2072	Shared Neighborhood Hits	50
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TEX10_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.021981 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXF1, Q5T722, Q5T723, Q8NCN8, Q8TDY0	Gene names	TEX10
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 10 protein.

TNNI3_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.018324 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P48787	Gene names	Tnni3
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

TPR_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.035890 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	1921	Shared Neighborhood Hits	48
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

IMA2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.056067 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.053443 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA5_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.052751 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

PP4R1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.061125 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.057858 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4RL_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.070398 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

SPAG6_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.060400 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

Hits sorted by NC score

GCN1L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

2AAA_MOUSE
NC score	0.309525 (rank : 2)	θ value	4.45536e-07 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
NC score	0.308415 (rank : 3)	θ value	5.81887e-07 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_HUMAN
NC score	0.305698 (rank : 4)	θ value	1.69304e-06 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	17
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
NC score	0.297839 (rank : 5)	θ value	8.40245e-06 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

ECM29_HUMAN
NC score	0.294421 (rank : 6)	θ value	1.38499e-08 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

ECM29_MOUSE
NC score	0.285792 (rank : 7)	θ value	5.26297e-08 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

HEAT2_HUMAN
NC score	0.259549 (rank : 8)	θ value	9.29e-05 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

IPO4_HUMAN
NC score	0.214496 (rank : 9)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
NC score	0.192243 (rank : 10)	θ value	0.00298849 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

CAND1_HUMAN
NC score	0.167885 (rank : 11)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	45	Shared Neighborhood Hits	21
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
NC score	0.164898 (rank : 12)	θ value	0.00509761 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CAND2_MOUSE
NC score	0.162424 (rank : 13)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

CAND2_HUMAN
NC score	0.155618 (rank : 14)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

SF3B1_HUMAN
NC score	0.140631 (rank : 15)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	341	Shared Neighborhood Hits	23
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.139018 (rank : 16)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TNPO1_HUMAN
NC score	0.129814 (rank : 17)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.129637 (rank : 18)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO2_MOUSE
NC score	0.121874 (rank : 19)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.119163 (rank : 20)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

FRAP_MOUSE
NC score	0.114586 (rank : 21)	θ value	0.00869519 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.113080 (rank : 22)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	83	Shared Neighborhood Hits	20
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IMB1_MOUSE
NC score	0.110166 (rank : 23)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

PLAK_MOUSE
NC score	0.107144 (rank : 24)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.107065 (rank : 25)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

IMB3_MOUSE
NC score	0.106666 (rank : 26)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.106375 (rank : 27)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB1_HUMAN
NC score	0.102910 (rank : 28)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

MMS19_MOUSE
NC score	0.100517 (rank : 29)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

MMS19_HUMAN
NC score	0.093505 (rank : 30)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T76, Q5T455, Q66K82, Q7L4W8, Q969Z1, Q96DF1, Q96MR1, Q96RK5, Q96SK1, Q9BUE2, Q9BYS9	Gene names	MMS19L, MMS19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (hMMS19) (MET18 homolog).

CTNB1_MOUSE
NC score	0.090198 (rank : 31)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.090194 (rank : 32)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

RNBP6_HUMAN
NC score	0.085216 (rank : 33)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

IMA4_MOUSE
NC score	0.084320 (rank : 34)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.084247 (rank : 35)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

SPAG6_MOUSE
NC score	0.076844 (rank : 36)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

IMA3_MOUSE
NC score	0.073272 (rank : 37)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.072266 (rank : 38)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

CT2NL_MOUSE
NC score	0.071639 (rank : 39)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	902	Shared Neighborhood Hits	37
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

COG3_HUMAN
NC score	0.070897 (rank : 40)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JB2, Q5VT70, Q8IXX4, Q9BZ92	Gene names	COG3, SEC34
Domain Architecture
Description	Conserved oligomeric Golgi complex component 3 (Vesicle docking protein SEC34 homolog) (p94).

PP4RL_HUMAN
NC score	0.070398 (rank : 41)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

CT2NL_HUMAN
NC score	0.068633 (rank : 42)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	1059	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CLAP1_HUMAN
NC score	0.068161 (rank : 43)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

COG3_MOUSE
NC score	0.063837 (rank : 44)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CI04	Gene names	Cog3
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 3.

HD_HUMAN
NC score	0.061707 (rank : 45)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

PP4R1_HUMAN
NC score	0.061125 (rank : 46)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

SPAG6_HUMAN
NC score	0.060400 (rank : 47)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

AKAP9_HUMAN
NC score	0.059686 (rank : 48)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	1710	Shared Neighborhood Hits	48
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

PFD6_HUMAN
NC score	0.058133 (rank : 49)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	O15212	Gene names	PFDN6, HKE2, PFD6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

PP4R1_MOUSE
NC score	0.057858 (rank : 50)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

RABE1_MOUSE
NC score	0.057508 (rank : 51)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	1105	Shared Neighborhood Hits	40
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

PFD6_MOUSE
NC score	0.056148 (rank : 52)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	152	Shared Neighborhood Hits	15
SwissProt Accessions	Q03958	Gene names	Pfdn6, H2-Ke2, Pfd6
Domain Architecture
Description	Prefoldin subunit 6 (Protein Ke2).

IMA2_HUMAN
NC score	0.056067 (rank : 53)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

K0423_HUMAN
NC score	0.055842 (rank : 54)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

RABE1_HUMAN
NC score	0.054233 (rank : 55)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	1104	Shared Neighborhood Hits	38
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

HD_MOUSE
NC score	0.053938 (rank : 56)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

IMA2_MOUSE
NC score	0.053443 (rank : 57)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA5_HUMAN
NC score	0.052751 (rank : 58)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

CCD50_HUMAN
NC score	0.051730 (rank : 59)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	237	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CP135_HUMAN
NC score	0.050498 (rank : 60)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	1290	Shared Neighborhood Hits	45
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RFIP3_HUMAN
NC score	0.049740 (rank : 61)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	1055	Shared Neighborhood Hits	38
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CKAP5_HUMAN
NC score	0.049635 (rank : 62)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

HMMR_MOUSE
NC score	0.049488 (rank : 63)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	1178	Shared Neighborhood Hits	38
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

PRR8_HUMAN
NC score	0.048340 (rank : 64)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

PEPL_MOUSE
NC score	0.047389 (rank : 65)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	1105	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

CCD50_MOUSE
NC score	0.046303 (rank : 66)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q810U5, Q3TRW1, Q8BP82, Q9CZT1, Q9D436	Gene names	Ccdc50
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

HMMR_HUMAN
NC score	0.045744 (rank : 67)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	1082	Shared Neighborhood Hits	43
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

GOGA3_HUMAN
NC score	0.045506 (rank : 68)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CP135_MOUSE
NC score	0.044876 (rank : 69)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	1278	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

IFT81_HUMAN
NC score	0.043761 (rank : 70)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	893	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

CCD46_MOUSE
NC score	0.042281 (rank : 71)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RB6I2_MOUSE
NC score	0.042096 (rank : 72)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	1433	Shared Neighborhood Hits	41
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

EEA1_MOUSE
NC score	0.041804 (rank : 73)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	1637	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

RB6I2_HUMAN
NC score	0.041758 (rank : 74)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	1584	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

IFT81_MOUSE
NC score	0.041705 (rank : 75)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	959	Shared Neighborhood Hits	40
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

GOGB1_HUMAN
NC score	0.041491 (rank : 76)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	2297	Shared Neighborhood Hits	54
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BPAEA_MOUSE
NC score	0.041209 (rank : 77)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	1480	Shared Neighborhood Hits	42
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MOT8_HUMAN
NC score	0.041157 (rank : 78)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

NEB2_HUMAN
NC score	0.041092 (rank : 79)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	883	Shared Neighborhood Hits	35
SwissProt Accessions	Q96SB3, Q8TCR9	Gene names	PPP1R9B
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

NEB2_MOUSE
NC score	0.040904 (rank : 80)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	889	Shared Neighborhood Hits	36
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

CCD46_HUMAN
NC score	0.040558 (rank : 81)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1430	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GCC2_HUMAN
NC score	0.040370 (rank : 82)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	1558	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.040262 (rank : 83)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	1559	Shared Neighborhood Hits	45
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GOGA4_HUMAN
NC score	0.039592 (rank : 84)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	2034	Shared Neighborhood Hits	47
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LIPA2_MOUSE
NC score	0.039393 (rank : 85)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	1282	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MACOI_HUMAN
NC score	0.039199 (rank : 86)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

ATR_HUMAN
NC score	0.037719 (rank : 87)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

ACINU_MOUSE
NC score	0.036263 (rank : 88)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	712	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TPR_HUMAN
NC score	0.035890 (rank : 89)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	1921	Shared Neighborhood Hits	48
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

APOB_HUMAN
NC score	0.034217 (rank : 90)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

MYH13_HUMAN
NC score	0.028367 (rank : 91)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	1504	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_HUMAN
NC score	0.028139 (rank : 92)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	1478	Shared Neighborhood Hits	47
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

KIF23_HUMAN
NC score	0.028113 (rank : 93)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

BFSP1_HUMAN
NC score	0.027018 (rank : 94)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	508	Shared Neighborhood Hits	38
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

MYO5C_HUMAN
NC score	0.026293 (rank : 95)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	1206	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RTN4_HUMAN
NC score	0.022236 (rank : 96)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TEX10_HUMAN
NC score	0.021981 (rank : 97)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXF1, Q5T722, Q5T723, Q8NCN8, Q8TDY0	Gene names	TEX10
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 10 protein.

ZMYM1_HUMAN
NC score	0.021367 (rank : 98)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SVZ6, Q7Z3Q4	Gene names	ZMYM1
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 1.

ROCK2_HUMAN
NC score	0.020599 (rank : 99)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	2073	Shared Neighborhood Hits	50
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
NC score	0.020002 (rank : 100)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	2072	Shared Neighborhood Hits	50
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SYHH_HUMAN
NC score	0.019923 (rank : 101)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P49590	Gene names	HARSL, HARSR, HO3
Domain Architecture
Description	Histidyl-tRNA synthetase homolog (EC 6.1.1.21) (Histidine--tRNA ligase homolog) (HisRS).

TRI25_HUMAN
NC score	0.019732 (rank : 102)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	472	Shared Neighborhood Hits	17
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

LDH6A_HUMAN
NC score	0.018524 (rank : 103)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZMR3	Gene names	LDHAL6A, LDHL2
Domain Architecture	No domain graphic available
Description	L-lactate dehydrogenase A-like 6A (EC 1.1.1.27).

TNNI3_MOUSE
NC score	0.018324 (rank : 104)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	P48787	Gene names	Tnni3
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

BTAF1_HUMAN
NC score	0.018256 (rank : 105)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

MRCKB_MOUSE
NC score	0.017618 (rank : 106)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	2180	Shared Neighborhood Hits	46
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PHF3_HUMAN
NC score	0.017354 (rank : 107)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

AT8A1_HUMAN
NC score	0.015359 (rank : 108)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Q0	Gene names	ATP8A1, ATPIA
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

AT8A1_MOUSE
NC score	0.014621 (rank : 109)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	P70704	Gene names	Atp8a1, Atpc1
Domain Architecture
Description	Probable phospholipid-transporting ATPase IA (EC 3.6.3.1) (Chromaffin granule ATPase II) (ATPase class I type 8A member 1).

RASL1_MOUSE
NC score	0.012613 (rank : 110)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

KI13A_MOUSE
NC score	0.011608 (rank : 111)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	395	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

NAL11_HUMAN
NC score	0.009881 (rank : 112)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

SYTL4_HUMAN
NC score	0.009049 (rank : 113)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

B4GT2_MOUSE
NC score	0.008690 (rank : 114)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2Y2, Q3TMP2	Gene names	B4galt2
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

ULK4_MOUSE
NC score	0.003867 (rank : 115)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	793	Shared Neighborhood Hits	10
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

STK36_HUMAN
NC score	0.003751 (rank : 116)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

FES_MOUSE
NC score	0.002462 (rank : 117)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	980	Shared Neighborhood Hits	20
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PCDGK_HUMAN
NC score	0.001515 (rank : 118)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UN70, O60622, Q08192, Q9Y5C4	Gene names	PCDHGC3, PCDH2
Domain Architecture
Description	Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2).

ZFP27_MOUSE
NC score	0.000504 (rank : 119)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	764	Shared Neighborhood Hits	3
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).