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Network neighborhood for query Sequence : 2AAB_HUMAN

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2AAB_HUMAN
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

2AAA_HUMAN
θ value	0 (rank : 1)	NC score	0.989453 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	0 (rank : 2)	NC score	0.989286 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
θ value	0 (rank : 4)	NC score	0.994027 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

PP4R1_MOUSE
θ value	5.08577e-11 (rank : 5)	NC score	0.434015 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_HUMAN
θ value	1.9326e-10 (rank : 6)	NC score	0.444916 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4RL_HUMAN
θ value	6.21693e-09 (rank : 7)	NC score	0.469704 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

GCN1L_HUMAN
θ value	1.69304e-06 (rank : 8)	NC score	0.305698 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

SF3B1_HUMAN
θ value	4.92598e-06 (rank : 9)	NC score	0.256303 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	4.92598e-06 (rank : 10)	NC score	0.255175 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

HEAT2_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.217558 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

PI3R4_HUMAN
θ value	0.00869519 (rank : 12)	NC score	0.125770 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

K0423_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.129884 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

FRAP_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.056673 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

HD_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.092674 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

IMB1_MOUSE
θ value	0.0563607 (rank : 16)	NC score	0.161741 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

K0423_HUMAN
θ value	0.0563607 (rank : 17)	NC score	0.118113 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

IMB1_HUMAN
θ value	0.0736092 (rank : 18)	NC score	0.158091 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

HEAT1_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.094586 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

PI3R4_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.124586 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

TNPO2_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.068935 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.081383 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

FRAP_MOUSE
θ value	0.21417 (rank : 23)	NC score	0.053410 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

GRP75_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.019864 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

RTDR1_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.137806 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

EP15R_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.011765 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	1135	Shared Neighborhood Hits	4
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

FGD6_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.015838 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD6_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.014847 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

GRP75_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.016325 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

EP15R_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.009165 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	1083	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

PACE1_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.042169 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

ARMC4_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.027404 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

STK36_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.007208 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	896	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

O13C4_HUMAN
θ value	6.88961 (rank : 34)	NC score	-0.001350 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	721	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGS5, Q96R41	Gene names	OR13C4
Domain Architecture
Description	Olfactory receptor 13C4.

PACE1_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.036757 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

LIPB2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.004728 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	599	Shared Neighborhood Hits	4
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

STAG3_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.006090 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

HD_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.056896 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

PCIF1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.057436 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

TNPO1_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.087799 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.088951 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

Hits sorted by NC score

2AAB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
NC score	0.994027 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAA_HUMAN
NC score	0.989453 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
NC score	0.989286 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

PP4RL_HUMAN
NC score	0.469704 (rank : 5)	θ value	6.21693e-09 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

PP4R1_HUMAN
NC score	0.444916 (rank : 6)	θ value	1.9326e-10 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	50	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
NC score	0.434015 (rank : 7)	θ value	5.08577e-11 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

GCN1L_HUMAN
NC score	0.305698 (rank : 8)	θ value	1.69304e-06 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

SF3B1_HUMAN
NC score	0.256303 (rank : 9)	θ value	4.92598e-06 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.255175 (rank : 10)	θ value	4.92598e-06 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

HEAT2_HUMAN
NC score	0.217558 (rank : 11)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

IMB1_MOUSE
NC score	0.161741 (rank : 12)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.158091 (rank : 13)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

RTDR1_HUMAN
NC score	0.137806 (rank : 14)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

K0423_MOUSE
NC score	0.129884 (rank : 15)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

PI3R4_HUMAN
NC score	0.125770 (rank : 16)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
NC score	0.124586 (rank : 17)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

K0423_HUMAN
NC score	0.118113 (rank : 18)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

HEAT1_HUMAN
NC score	0.094586 (rank : 19)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

HD_HUMAN
NC score	0.092674 (rank : 20)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

TNPO1_MOUSE
NC score	0.088951 (rank : 21)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.087799 (rank : 22)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	64	Shared Neighborhood Hits	14
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO2_MOUSE
NC score	0.081383 (rank : 23)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.068935 (rank : 24)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

PCIF1_HUMAN
NC score	0.057436 (rank : 25)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

HD_MOUSE
NC score	0.056896 (rank : 26)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

FRAP_HUMAN
NC score	0.056673 (rank : 27)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
NC score	0.053410 (rank : 28)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

PACE1_HUMAN
NC score	0.042169 (rank : 29)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PACE1_MOUSE
NC score	0.036757 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

ARMC4_HUMAN
NC score	0.027404 (rank : 31)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

GRP75_MOUSE
NC score	0.019864 (rank : 32)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
NC score	0.016325 (rank : 33)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

FGD6_MOUSE
NC score	0.015838 (rank : 34)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

FGD6_HUMAN
NC score	0.014847 (rank : 35)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

EP15R_MOUSE
NC score	0.011765 (rank : 36)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	1135	Shared Neighborhood Hits	4
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15R_HUMAN
NC score	0.009165 (rank : 37)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	1083	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

STK36_HUMAN
NC score	0.007208 (rank : 38)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	896	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

STAG3_HUMAN
NC score	0.006090 (rank : 39)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ98, Q8NDP3	Gene names	STAG3
Domain Architecture
Description	Cohesin subunit SA-3 (Stromal antigen 3) (Stromalin 3) (SCC3 homolog 3).

LIPB2_HUMAN
NC score	0.004728 (rank : 40)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	599	Shared Neighborhood Hits	4
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

O13C4_HUMAN
NC score	-0.001350 (rank : 41)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	721	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGS5, Q96R41	Gene names	OR13C4
Domain Architecture
Description	Olfactory receptor 13C4.