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Network neighborhood for query Sequence : HD_MOUSE

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HD_MOUSE
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HD_HUMAN
θ value	0 (rank : 1)	NC score	0.977056 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HD_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

DSPP_HUMAN
θ value	0.00175202 (rank : 3)	NC score	0.099636 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	645	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_MOUSE
θ value	0.00390308 (rank : 4)	NC score	0.113414 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MKL1_MOUSE
θ value	0.0113563 (rank : 5)	NC score	0.065362 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	667	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

TSC2_MOUSE
θ value	0.0330416 (rank : 6)	NC score	0.054327 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

LEO1_MOUSE
θ value	0.0961366 (rank : 7)	NC score	0.050168 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

2AAA_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.075300 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

AKAP6_HUMAN
θ value	0.279714 (rank : 9)	NC score	0.046316 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

SON_HUMAN
θ value	0.279714 (rank : 10)	NC score	0.043549 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	1568	Shared Neighborhood Hits	43
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

2AAA_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.068315 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

AN32B_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.038636 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

JPH2_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.039917 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	639	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SRCA_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.034207 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

GATA6_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.049329 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

DUET_HUMAN
θ value	0.813845 (rank : 16)	NC score	0.007714 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	1220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

LEO1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.060416 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LRC47_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.035166 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	299	Shared Neighborhood Hits	5
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

SF3B1_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.062822 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.062753 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TCF7_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.034246 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	277	Shared Neighborhood Hits	6
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

GAK5_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.050179 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	429	Shared Neighborhood Hits	21
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PPRB_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.063524 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PSL1_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.054200 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

TOPRS_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.037388 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ATX7_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.048272 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	328	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CD2_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.075044 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	504	Shared Neighborhood Hits	25
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

GATA6_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.039921 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

ILDR1_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.032383 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

AMBN_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.043800 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

BTBDC_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.034661 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

ITA4_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.011966 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

NFAT5_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.020315 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

PPRB_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.044893 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	311	Shared Neighborhood Hits	16
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

CC021_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.045552 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U4G3, Q3TLX5, Q8K2I0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf21 homolog.

GCN1L_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.053938 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IRF3_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.023956 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

KCNH8_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.011008 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

M4K1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.002527 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MOCOS_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.025682 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

PF21B_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.021416 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TOPRS_MOUSE
θ value	2.36792 (rank : 42)	NC score	0.038940 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	263	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TPR_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.006570 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	1921	Shared Neighborhood Hits	22
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZCH10_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.049413 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

4ET_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.036893 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CRSP7_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.027870 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

DZIP3_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.017131 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	414	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

GAK11_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.047207 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK12_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.047493 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.040558 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.047038 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.047271 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.046276 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	392	Shared Neighborhood Hits	20
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PEX14_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.029314 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

PHF14_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.018835 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RGS3_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.024108 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	1375	Shared Neighborhood Hits	36
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TARSH_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.038661 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	768	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TF65_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.017586 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TSKS_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.022790 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

CD3E_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.028809 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P22646	Gene names	Cd3e
Domain Architecture
Description	T-cell surface glycoprotein CD3 epsilon chain precursor (T-cell surface antigen T3/Leu-4 epsilon chain).

CO039_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.026348 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	264	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

COFA1_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.014275 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

CT032_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.025794 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DOHH_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.024895 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU89, O75265	Gene names	DOHH, HLRC1
Domain Architecture	No domain graphic available
Description	Deoxyhypusine hydroxylase (EC 1.14.99.29) (Deoxyhypusine monooxygenase) (hDOHH) (HEAT-like repeat-containing protein 1).

FBX18_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.027189 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

MYO15_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.008533 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	671	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OAS3_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.016435 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

RGS3_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.021136 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RPGF5_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.012307 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

SL9A8_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.025912 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4D1, Q3UPR4, Q5WA59, Q8BIH8, Q8BJ27	Gene names	Slc9a8, Nhe8
Domain Architecture
Description	Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8).

SPR1A_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.045868 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SRRM1_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.036430 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	966	Shared Neighborhood Hits	38
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.021754 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TFE2_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.014416 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

ADA12_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.005244 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	474	Shared Neighborhood Hits	10
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ANGT_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.011307 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P11859	Gene names	Agt, Serpina8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

AUTS2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.039052 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CABIN_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.029565 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	490	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAND2_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.021005 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

FOXN4_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.018585 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	248	Shared Neighborhood Hits	7
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

HGS_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.030253 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	517	Shared Neighborhood Hits	13
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MLL3_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.028263 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	1644	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MTF1_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.000500 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	814	Shared Neighborhood Hits	10
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NUFP1_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.030110 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	193	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PCLO_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.023680 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PIGG_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.019189 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

SL9A8_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.023724 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2E8, Q68CZ8, Q9BX15, Q9Y507	Gene names	SLC9A8, KIAA0939, NHE8
Domain Architecture
Description	Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8).

SPEG_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.007174 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	1959	Shared Neighborhood Hits	43
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPR1B_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.034065 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	395	Shared Neighborhood Hits	16
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TPO_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.032998 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

AKAP2_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.019278 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

BAG3_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.017681 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	513	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CEL_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.008432 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	896	Shared Neighborhood Hits	27
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CJ026_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.037253 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX94, Q2HIY7, Q5F2G6	Gene names	C10orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26.

DTX1_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.024346 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

DTX1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.025599 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

ETV5_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.012641 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

RFXK_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.004941 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

SMG1_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.018928 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.018824 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SON_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.043144 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPAG5_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.008358 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	625	Shared Neighborhood Hits	9
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

TCF7_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.027738 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

AKP8L_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.015634 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

APS_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.008858 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

CHD9_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.005319 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DNMBP_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.007693 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	413	Shared Neighborhood Hits	8
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

IMA7_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.009483 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IWS1_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.026318 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MNT_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.021267 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	496	Shared Neighborhood Hits	29
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NADAP_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.016676 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

PDLI7_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.006102 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	547	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PDXL2_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.016862 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SORC1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.006406 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

ZBED1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.025108 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O96006, Q96BY4	Gene names	ZBED1, ALTE, DREF, KIAA0785, TRAMP
Domain Architecture
Description	Zinc finger BED domain-containing protein 1 (dREF homolog) (Putative Ac-like transposable element).

ZC11A_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.011548 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

2AAB_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.056896 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.058764 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

Hits sorted by NC score

HD_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	116	Target Neighborhood Hits	116	Shared Neighborhood Hits	116
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

HD_HUMAN
NC score	0.977056 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	116	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

DSPP_MOUSE
NC score	0.113414 (rank : 3)	θ value	0.00390308 (rank : 4)
Query Neighborhood Hits	116	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.099636 (rank : 4)	θ value	0.00175202 (rank : 3)
Query Neighborhood Hits	116	Target Neighborhood Hits	645	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

2AAA_MOUSE
NC score	0.075300 (rank : 5)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

CD2_HUMAN
NC score	0.075044 (rank : 6)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	116	Target Neighborhood Hits	504	Shared Neighborhood Hits	25
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

2AAA_HUMAN
NC score	0.068315 (rank : 7)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	116	Target Neighborhood Hits	42	Shared Neighborhood Hits	8
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

MKL1_MOUSE
NC score	0.065362 (rank : 8)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	116	Target Neighborhood Hits	667	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PPRB_MOUSE
NC score	0.063524 (rank : 9)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	116	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SF3B1_HUMAN
NC score	0.062822 (rank : 10)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	116	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.062753 (rank : 11)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	116	Target Neighborhood Hits	352	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

LEO1_HUMAN
NC score	0.060416 (rank : 12)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	116	Target Neighborhood Hits	958	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

2AAB_MOUSE
NC score	0.058764 (rank : 13)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	116	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
NC score	0.056896 (rank : 14)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	116	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

TSC2_MOUSE
NC score	0.054327 (rank : 15)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	116	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

PSL1_HUMAN
NC score	0.054200 (rank : 16)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	116	Target Neighborhood Hits	650	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

GCN1L_HUMAN
NC score	0.053938 (rank : 17)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	116	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

GAK5_HUMAN
NC score	0.050179 (rank : 18)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	116	Target Neighborhood Hits	429	Shared Neighborhood Hits	21
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LEO1_MOUSE
NC score	0.050168 (rank : 19)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	116	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ZCH10_MOUSE
NC score	0.049413 (rank : 20)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	116	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

GATA6_MOUSE
NC score	0.049329 (rank : 21)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	116	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q61169, P97729, Q9QZK3	Gene names	Gata6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

ATX7_MOUSE
NC score	0.048272 (rank : 22)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	116	Target Neighborhood Hits	328	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

GAK12_HUMAN
NC score	0.047493 (rank : 23)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	116	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.047271 (rank : 24)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	116	Target Neighborhood Hits	415	Shared Neighborhood Hits	20
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.047207 (rank : 25)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	116	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.047038 (rank : 26)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	116	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

AKAP6_HUMAN
NC score	0.046316 (rank : 27)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	116	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

GAK6_HUMAN
NC score	0.046276 (rank : 28)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	116	Target Neighborhood Hits	392	Shared Neighborhood Hits	20
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

SPR1A_MOUSE
NC score	0.045868 (rank : 29)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	116	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CC021_MOUSE
NC score	0.045552 (rank : 30)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	116	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U4G3, Q3TLX5, Q8K2I0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C3orf21 homolog.

PPRB_HUMAN
NC score	0.044893 (rank : 31)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	116	Target Neighborhood Hits	311	Shared Neighborhood Hits	16
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

AMBN_HUMAN
NC score	0.043800 (rank : 32)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	116	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NP70, Q9H2X1, Q9H4L1	Gene names	AMBN
Domain Architecture
Description	Ameloblastin precursor.

SON_HUMAN
NC score	0.043549 (rank : 33)	θ value	0.279714 (rank : 10)
Query Neighborhood Hits	116	Target Neighborhood Hits	1568	Shared Neighborhood Hits	43
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
NC score	0.043144 (rank : 34)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	116	Target Neighborhood Hits	957	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GAK1_HUMAN
NC score	0.040558 (rank : 35)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	116	Target Neighborhood Hits	268	Shared Neighborhood Hits	16
SwissProt Accessions	P62683	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GATA6_HUMAN
NC score	0.039921 (rank : 36)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	116	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q92908, P78327	Gene names	GATA6
Domain Architecture
Description	Transcription factor GATA-6 (GATA-binding factor 6).

JPH2_HUMAN
NC score	0.039917 (rank : 37)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	116	Target Neighborhood Hits	639	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

AUTS2_HUMAN
NC score	0.039052 (rank : 38)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

TOPRS_MOUSE
NC score	0.038940 (rank : 39)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	116	Target Neighborhood Hits	263	Shared Neighborhood Hits	6
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TARSH_HUMAN
NC score	0.038661 (rank : 40)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	116	Target Neighborhood Hits	768	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

AN32B_MOUSE
NC score	0.038636 (rank : 41)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	116	Target Neighborhood Hits	236	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EST5	Gene names	Anp32b, Pal31
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (Proliferation-related acidic leucine-rich protein PAL31).

TOPRS_HUMAN
NC score	0.037388 (rank : 42)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	116	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CJ026_HUMAN
NC score	0.037253 (rank : 43)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	116	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NX94, Q2HIY7, Q5F2G6	Gene names	C10orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26.

4ET_HUMAN
NC score	0.036893 (rank : 44)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	116	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

SRRM1_MOUSE
NC score	0.036430 (rank : 45)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	116	Target Neighborhood Hits	966	Shared Neighborhood Hits	38
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

LRC47_MOUSE
NC score	0.035166 (rank : 46)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	116	Target Neighborhood Hits	299	Shared Neighborhood Hits	5
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

BTBDC_HUMAN
NC score	0.034661 (rank : 47)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	116	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

TCF7_MOUSE
NC score	0.034246 (rank : 48)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	116	Target Neighborhood Hits	277	Shared Neighborhood Hits	6
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SRCA_HUMAN
NC score	0.034207 (rank : 49)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	116	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SPR1B_MOUSE
NC score	0.034065 (rank : 50)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	116	Target Neighborhood Hits	395	Shared Neighborhood Hits	16
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TPO_MOUSE
NC score	0.032998 (rank : 51)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	116	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

ILDR1_HUMAN
NC score	0.032383 (rank : 52)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	116	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q86SU0, Q6ZP61, Q7Z578	Gene names	ILDR1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

HGS_HUMAN
NC score	0.030253 (rank : 53)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	116	Target Neighborhood Hits	517	Shared Neighborhood Hits	13
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

NUFP1_HUMAN
NC score	0.030110 (rank : 54)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	116	Target Neighborhood Hits	193	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHK0, Q8WVM5, Q96SG1	Gene names	NUFIP1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

CABIN_HUMAN
NC score	0.029565 (rank : 55)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	116	Target Neighborhood Hits	490	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

PEX14_HUMAN
NC score	0.029314 (rank : 56)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	116	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	O75381, Q8WX51	Gene names	PEX14
Domain Architecture
Description	Peroxisomal membrane protein PEX14 (Peroxin-14) (Peroxisomal membrane anchor protein PEX14) (PTS1 receptor docking protein).

CD3E_MOUSE
NC score	0.028809 (rank : 57)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	116	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P22646	Gene names	Cd3e
Domain Architecture
Description	T-cell surface glycoprotein CD3 epsilon chain precursor (T-cell surface antigen T3/Leu-4 epsilon chain).

MLL3_HUMAN
NC score	0.028263 (rank : 58)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	116	Target Neighborhood Hits	1644	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CRSP7_HUMAN
NC score	0.027870 (rank : 59)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	116	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

TCF7_HUMAN
NC score	0.027738 (rank : 60)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	116	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

FBX18_HUMAN
NC score	0.027189 (rank : 61)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

CO039_HUMAN
NC score	0.026348 (rank : 62)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	116	Target Neighborhood Hits	264	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

IWS1_MOUSE
NC score	0.026318 (rank : 63)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	116	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SL9A8_MOUSE
NC score	0.025912 (rank : 64)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	116	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4D1, Q3UPR4, Q5WA59, Q8BIH8, Q8BJ27	Gene names	Slc9a8, Nhe8
Domain Architecture
Description	Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8).

CT032_HUMAN
NC score	0.025794 (rank : 65)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	116	Target Neighborhood Hits	235	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

MOCOS_HUMAN
NC score	0.025682 (rank : 66)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	116	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EN8, Q53GP5, Q8N3A4, Q9NWM7	Gene names	MOCOS
Domain Architecture	No domain graphic available
Description	Molybdenum cofactor sulfurase (EC 4.4.-.-) (MoCo sulfurase) (MOS) (HMCS).

DTX1_MOUSE
NC score	0.025599 (rank : 67)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	116	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q61010, Q3TER5, Q8C2H2, Q9ER09	Gene names	Dtx1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (mDTX1) (FXI-T1).

ZBED1_HUMAN
NC score	0.025108 (rank : 68)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	116	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O96006, Q96BY4	Gene names	ZBED1, ALTE, DREF, KIAA0785, TRAMP
Domain Architecture
Description	Zinc finger BED domain-containing protein 1 (dREF homolog) (Putative Ac-like transposable element).

DOHH_HUMAN
NC score	0.024895 (rank : 69)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	116	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU89, O75265	Gene names	DOHH, HLRC1
Domain Architecture	No domain graphic available
Description	Deoxyhypusine hydroxylase (EC 1.14.99.29) (Deoxyhypusine monooxygenase) (hDOHH) (HEAT-like repeat-containing protein 1).

DTX1_HUMAN
NC score	0.024346 (rank : 70)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	116	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

RGS3_HUMAN
NC score	0.024108 (rank : 71)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	116	Target Neighborhood Hits	1375	Shared Neighborhood Hits	36
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IRF3_HUMAN
NC score	0.023956 (rank : 72)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	116	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

SL9A8_HUMAN
NC score	0.023724 (rank : 73)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	116	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2E8, Q68CZ8, Q9BX15, Q9Y507	Gene names	SLC9A8, KIAA0939, NHE8
Domain Architecture
Description	Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8).

PCLO_MOUSE
NC score	0.023680 (rank : 74)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	116	Target Neighborhood Hits	2275	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TSKS_MOUSE
NC score	0.022790 (rank : 75)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	116	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

SRRM2_MOUSE
NC score	0.021754 (rank : 76)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	116	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PF21B_MOUSE
NC score	0.021416 (rank : 77)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	116	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MNT_HUMAN
NC score	0.021267 (rank : 78)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	116	Target Neighborhood Hits	496	Shared Neighborhood Hits	29
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RGS3_MOUSE
NC score	0.021136 (rank : 79)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	116	Target Neighborhood Hits	1621	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CAND2_MOUSE
NC score	0.021005 (rank : 80)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	116	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

NFAT5_MOUSE
NC score	0.020315 (rank : 81)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	116	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

AKAP2_MOUSE
NC score	0.019278 (rank : 82)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	116	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

PIGG_HUMAN
NC score	0.019189 (rank : 83)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	116	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q5H8A4, Q2TAK5, Q6UX31, Q7L5Y4, Q8N866, Q8NCC9, Q96SY9, Q9BVT7, Q9NXG5	Gene names	PIGG, GPI7
Domain Architecture	No domain graphic available
Description	GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) (GPI7 homolog) (hGPI7).

SMG1_HUMAN
NC score	0.018928 (rank : 84)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	116	Target Neighborhood Hits	231	Shared Neighborhood Hits	6
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

PHF14_MOUSE
NC score	0.018835 (rank : 85)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	116	Target Neighborhood Hits	342	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

SMG1_MOUSE
NC score	0.018824 (rank : 86)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	116	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

FOXN4_HUMAN
NC score	0.018585 (rank : 87)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	116	Target Neighborhood Hits	248	Shared Neighborhood Hits	7
SwissProt Accessions	Q96NZ1, Q6ZMR4, Q96NZ0	Gene names	FOXN4
Domain Architecture	No domain graphic available
Description	Forkhead box protein N4.

BAG3_MOUSE
NC score	0.017681 (rank : 88)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	116	Target Neighborhood Hits	513	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

TF65_HUMAN
NC score	0.017586 (rank : 89)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	116	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

DZIP3_MOUSE
NC score	0.017131 (rank : 90)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	116	Target Neighborhood Hits	414	Shared Neighborhood Hits	9
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

PDXL2_HUMAN
NC score	0.016862 (rank : 91)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	116	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

NADAP_HUMAN
NC score	0.016676 (rank : 92)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	116	Target Neighborhood Hits	208	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

OAS3_HUMAN
NC score	0.016435 (rank : 93)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	116	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

AKP8L_MOUSE
NC score	0.015634 (rank : 94)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	116	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

TFE2_HUMAN
NC score	0.014416 (rank : 95)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	116	Target Neighborhood Hits	161	Shared Neighborhood Hits	4
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

COFA1_HUMAN
NC score	0.014275 (rank : 96)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	116	Target Neighborhood Hits	292	Shared Neighborhood Hits	14
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

ETV5_HUMAN
NC score	0.012641 (rank : 97)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	116	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

RPGF5_MOUSE
NC score	0.012307 (rank : 98)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	116	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0Q9, Q8BJJ9, Q8C0R5	Gene names	Rapgef5, Gfr, Kiaa0277, Mrgef
Domain Architecture
Description	Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF).

ITA4_HUMAN
NC score	0.011966 (rank : 99)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	116	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13612	Gene names	ITGA4
Domain Architecture
Description	Integrin alpha-4 precursor (Integrin alpha-IV) (VLA-4) (CD49d antigen).

ZC11A_MOUSE
NC score	0.011548 (rank : 100)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	116	Target Neighborhood Hits	216	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZF1, Q6NXW9, Q6PDR6, Q80TU7, Q8C5L5, Q99JN6	Gene names	Zc3h11a, Kiaa0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ANGT_MOUSE
NC score	0.011307 (rank : 101)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	116	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P11859	Gene names	Agt, Serpina8
Domain Architecture
Description	Angiotensinogen precursor [Contains: Angiotensin-1 (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II)].

KCNH8_HUMAN
NC score	0.011008 (rank : 102)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	116	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

IMA7_HUMAN
NC score	0.009483 (rank : 103)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	116	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

APS_MOUSE
NC score	0.008858 (rank : 104)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	116	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

MYO15_HUMAN
NC score	0.008533 (rank : 105)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	116	Target Neighborhood Hits	671	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CEL_HUMAN
NC score	0.008432 (rank : 106)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	116	Target Neighborhood Hits	896	Shared Neighborhood Hits	27
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SPAG5_HUMAN
NC score	0.008358 (rank : 107)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	116	Target Neighborhood Hits	625	Shared Neighborhood Hits	9
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

DUET_HUMAN
NC score	0.007714 (rank : 108)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	116	Target Neighborhood Hits	1220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

DNMBP_HUMAN
NC score	0.007693 (rank : 109)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	116	Target Neighborhood Hits	413	Shared Neighborhood Hits	8
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SPEG_MOUSE
NC score	0.007174 (rank : 110)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	116	Target Neighborhood Hits	1959	Shared Neighborhood Hits	43
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TPR_HUMAN
NC score	0.006570 (rank : 111)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	116	Target Neighborhood Hits	1921	Shared Neighborhood Hits	22
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SORC1_MOUSE
NC score	0.006406 (rank : 112)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	116	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

PDLI7_HUMAN
NC score	0.006102 (rank : 113)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	116	Target Neighborhood Hits	547	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

CHD9_MOUSE
NC score	0.005319 (rank : 114)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	116	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ADA12_MOUSE
NC score	0.005244 (rank : 115)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	116	Target Neighborhood Hits	474	Shared Neighborhood Hits	10
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

RFXK_HUMAN
NC score	0.004941 (rank : 116)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	116	Target Neighborhood Hits	282	Shared Neighborhood Hits	2
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

M4K1_MOUSE
NC score	0.002527 (rank : 117)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	116	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	P70218, Q8R3R0, Q99K62	Gene names	Map4k1, Hpk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase) (HPK).

MTF1_HUMAN
NC score	0.000500 (rank : 118)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	116	Target Neighborhood Hits	814	Shared Neighborhood Hits	10
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).