Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : KCNH8_HUMAN

For an explanation of this page, click here

KCNH8_HUMAN
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH3_HUMAN
θ value	0 (rank : 1)	NC score	0.984717 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	148	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	0 (rank : 2)	NC score	0.984758 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH4_HUMAN
θ value	0 (rank : 3)	NC score	0.988115 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
θ value	2.95243e-160 (rank : 5)	NC score	0.968133 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	222	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH1_HUMAN
θ value	1.28961e-139 (rank : 6)	NC score	0.968590 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH5_MOUSE
θ value	1.28961e-139 (rank : 7)	NC score	0.968588 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH1_MOUSE
θ value	1.68428e-139 (rank : 8)	NC score	0.968716 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_HUMAN
θ value	2.19974e-139 (rank : 9)	NC score	0.968428 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH7_MOUSE
θ value	5.61992e-127 (rank : 10)	NC score	0.960306 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH2_HUMAN
θ value	4.75757e-126 (rank : 11)	NC score	0.960370 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	6.21357e-126 (rank : 12)	NC score	0.960275 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_HUMAN
θ value	1.99884e-124 (rank : 13)	NC score	0.959333 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA1_HUMAN
θ value	8.61488e-35 (rank : 14)	NC score	0.808073 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	35
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN4_MOUSE
θ value	1.9192e-34 (rank : 15)	NC score	0.772171 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA1_MOUSE
θ value	9.52487e-34 (rank : 16)	NC score	0.803774 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HCN4_HUMAN
θ value	3.61944e-33 (rank : 17)	NC score	0.773961 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	303	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CNGA2_MOUSE
θ value	4.72714e-33 (rank : 18)	NC score	0.817702 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

HCN2_MOUSE
θ value	4.72714e-33 (rank : 19)	NC score	0.776791 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	278	Shared Neighborhood Hits	38
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

CNGA3_HUMAN
θ value	8.06329e-33 (rank : 20)	NC score	0.802989 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN2_HUMAN
θ value	1.0531e-32 (rank : 21)	NC score	0.767470 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN1_MOUSE
θ value	5.22648e-32 (rank : 22)	NC score	0.789504 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN1_HUMAN
θ value	6.82597e-32 (rank : 23)	NC score	0.793221 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

CNGA3_MOUSE
θ value	8.91499e-32 (rank : 24)	NC score	0.806520 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN3_HUMAN
θ value	4.57862e-28 (rank : 25)	NC score	0.787354 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.33217e-27 (rank : 26)	NC score	0.787246 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

CNGB3_MOUSE
θ value	9.56915e-18 (rank : 27)	NC score	0.741179 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	3.63628e-17 (rank : 28)	NC score	0.728519 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
θ value	1.16975e-15 (rank : 29)	NC score	0.724180 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	222	Shared Neighborhood Hits	39
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
θ value	0.000158464 (rank : 30)	NC score	0.258199 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK2_HUMAN
θ value	0.00869519 (rank : 31)	NC score	0.188297 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.187561 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

ANR21_HUMAN
θ value	0.0113563 (rank : 33)	NC score	0.013257 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	864	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

NCOR2_MOUSE
θ value	0.0113563 (rank : 34)	NC score	0.042796 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

KCNS2_HUMAN
θ value	0.0193708 (rank : 35)	NC score	0.052243 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	0.0193708 (rank : 36)	NC score	0.051807 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNK4_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.172892 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCMA1_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.081971 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.082080 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCND1_HUMAN
θ value	0.0736092 (rank : 40)	NC score	0.075400 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNK1_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.133663 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
θ value	0.0961366 (rank : 42)	NC score	0.129494 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK6_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.180145 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

NCOR2_HUMAN
θ value	0.0961366 (rank : 44)	NC score	0.031658 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

KCND1_MOUSE
θ value	0.125558 (rank : 45)	NC score	0.081172 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNK4_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.160256 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	118	Shared Neighborhood Hits	40
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCND2_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.073591 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	154	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.163984 (rank : 48)	NC score	0.073620 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

POT15_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.010994 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	893	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

IL7RA_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.027233 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

KCNKA_HUMAN
θ value	0.21417 (rank : 51)	NC score	0.181147 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	45
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK3_HUMAN
θ value	0.279714 (rank : 52)	NC score	0.179237 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	0.279714 (rank : 53)	NC score	0.175758 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKF_HUMAN
θ value	0.279714 (rank : 54)	NC score	0.188275 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

IRK13_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.014596 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

KCND3_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.071750 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.365318 (rank : 57)	NC score	0.071754 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

AF17_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.013402 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	230	Shared Neighborhood Hits	5
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

KCNK9_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.151495 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.813845 (rank : 60)	NC score	0.151517 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

LRCH2_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.008148 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

KCNA4_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.034769 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

GP108_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.011742 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

KGP1A_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.040156 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	901	Shared Neighborhood Hits	36
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.040161 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

NDE1_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.004398 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	823	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

AP4E1_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.009701 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

CKLF_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.026164 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

HD_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.011008 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

KGP1B_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.039755 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP2_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.028954 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	1023	Shared Neighborhood Hits	30
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

LRCH2_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.008797 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

RAI14_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.000816 (rank : 113)
Query Neighborhood Hits	104	Target Neighborhood Hits	1367	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

KCNKG_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.164679 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

NAB2_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.010081 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

TRI73_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.005835 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

ZHX3_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.006807 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

BRSK2_HUMAN
θ value	4.03905 (rank : 78)	NC score	-0.002672 (rank : 116)
Query Neighborhood Hits	104	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

KCNN4_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.038761 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

MTR1L_HUMAN
θ value	4.03905 (rank : 80)	NC score	-0.001526 (rank : 115)
Query Neighborhood Hits	104	Target Neighborhood Hits	1180	Shared Neighborhood Hits	7
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

OR2V2_HUMAN
θ value	4.03905 (rank : 81)	NC score	-0.004130 (rank : 118)
Query Neighborhood Hits	104	Target Neighborhood Hits	788	Shared Neighborhood Hits	2
SwissProt Accessions	Q96R30, Q6IFL6, Q8NGV1	Gene names	OR2V2, OR2V3
Domain Architecture
Description	Olfactory receptor 2V2 (Olfactory receptor OR5-3).

PROM1_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.012987 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

APOA_HUMAN
θ value	5.27518 (rank : 83)	NC score	-0.000148 (rank : 114)
Query Neighborhood Hits	104	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

KCNA4_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.030935 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNN2_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.028771 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.028748 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KGP2_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.028199 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	1029	Shared Neighborhood Hits	29
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

LARP1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.018263 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

T2FA_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.009622 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TINF2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.010810 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

TRI50_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.002536 (rank : 111)
Query Neighborhood Hits	104	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

BCL7A_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.006859 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

FA35A_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.007902 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

KCNB2_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.038897 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNK5_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.130061 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

MAP1B_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.003582 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RFIP1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.007494 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RPGR_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.003169 (rank : 110)
Query Neighborhood Hits	104	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

TRI74_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.004809 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

AGGF1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.013791 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

CEP35_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002024 (rank : 112)
Query Neighborhood Hits	104	Target Neighborhood Hits	811	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

MTR1L_MOUSE
θ value	8.99809 (rank : 102)	NC score	-0.003327 (rank : 117)
Query Neighborhood Hits	104	Target Neighborhood Hits	903	Shared Neighborhood Hits	3
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

PROM1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.010856 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O43490	Gene names	PROM1, PROML1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133) (CD133 antigen).

TP53B_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.010654 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	644	Shared Neighborhood Hits	10
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CT152_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.060555 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP0_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.128849 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.117243 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.106325 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.103875 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.075581 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.077626 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.075624 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.078896 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCNK7_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.058607 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.076437 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.068393 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.071252 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.089190 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

Hits sorted by NC score

KCNH8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.988115 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	177	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH3_MOUSE
NC score	0.984758 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.984717 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	148	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH1_MOUSE
NC score	0.968716 (rank : 5)	θ value	1.68428e-139 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.968590 (rank : 6)	θ value	1.28961e-139 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH5_MOUSE
NC score	0.968588 (rank : 7)	θ value	1.28961e-139 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.968428 (rank : 8)	θ value	2.19974e-139 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH6_HUMAN
NC score	0.968133 (rank : 9)	θ value	2.95243e-160 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	222	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.960370 (rank : 10)	θ value	4.75757e-126 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
NC score	0.960306 (rank : 11)	θ value	5.61992e-127 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH2_MOUSE
NC score	0.960275 (rank : 12)	θ value	6.21357e-126 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_HUMAN
NC score	0.959333 (rank : 13)	θ value	1.99884e-124 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA2_MOUSE
NC score	0.817702 (rank : 14)	θ value	4.72714e-33 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.808073 (rank : 15)	θ value	8.61488e-35 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	35
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.806520 (rank : 16)	θ value	8.91499e-32 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.803774 (rank : 17)	θ value	9.52487e-34 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.802989 (rank : 18)	θ value	8.06329e-33 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.793221 (rank : 19)	θ value	6.82597e-32 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.789504 (rank : 20)	θ value	5.22648e-32 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_HUMAN
NC score	0.787354 (rank : 21)	θ value	4.57862e-28 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
NC score	0.787246 (rank : 22)	θ value	1.33217e-27 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	112	Shared Neighborhood Hits	34
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN2_MOUSE
NC score	0.776791 (rank : 23)	θ value	4.72714e-33 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	278	Shared Neighborhood Hits	38
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.773961 (rank : 24)	θ value	3.61944e-33 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	303	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.772171 (rank : 25)	θ value	1.9192e-34 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.767470 (rank : 26)	θ value	1.0531e-32 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	369	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.741179 (rank : 27)	θ value	9.56915e-18 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.728519 (rank : 28)	θ value	3.63628e-17 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	206	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.724180 (rank : 29)	θ value	1.16975e-15 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	222	Shared Neighborhood Hits	39
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.258199 (rank : 30)	θ value	0.000158464 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK2_HUMAN
NC score	0.188297 (rank : 31)	θ value	0.00869519 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNKF_HUMAN
NC score	0.188275 (rank : 32)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_MOUSE
NC score	0.187561 (rank : 33)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	41
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNKA_HUMAN
NC score	0.181147 (rank : 34)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	45
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.180145 (rank : 35)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	79	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_HUMAN
NC score	0.179237 (rank : 36)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.175758 (rank : 37)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
NC score	0.172892 (rank : 38)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	109	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.164679 (rank : 39)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK4_MOUSE
NC score	0.160256 (rank : 40)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	118	Shared Neighborhood Hits	40
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK9_MOUSE
NC score	0.151517 (rank : 41)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.151495 (rank : 42)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK1_HUMAN
NC score	0.133663 (rank : 43)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK5_HUMAN
NC score	0.130061 (rank : 44)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK1_MOUSE
NC score	0.129494 (rank : 45)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KAP0_HUMAN
NC score	0.128849 (rank : 46)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.117243 (rank : 47)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.106325 (rank : 48)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.103875 (rank : 49)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNKD_MOUSE
NC score	0.089190 (rank : 50)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCMA1_MOUSE
NC score	0.082080 (rank : 51)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.081971 (rank : 52)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCND1_MOUSE
NC score	0.081172 (rank : 53)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KAP3_MOUSE
NC score	0.078896 (rank : 54)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	104	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.077626 (rank : 55)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	104	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KCNK7_MOUSE
NC score	0.076437 (rank : 56)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	104	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KAP3_HUMAN
NC score	0.075624 (rank : 57)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	104	Target Neighborhood Hits	40	Shared Neighborhood Hits	21
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_HUMAN
NC score	0.075581 (rank : 58)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	104	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KCND1_HUMAN
NC score	0.075400 (rank : 59)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_MOUSE
NC score	0.073620 (rank : 60)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	156	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.073591 (rank : 61)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	154	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_MOUSE
NC score	0.071754 (rank : 62)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.071750 (rank : 63)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNKD_HUMAN
NC score	0.071252 (rank : 64)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKC_HUMAN
NC score	0.068393 (rank : 65)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

CT152_MOUSE
NC score	0.060555 (rank : 66)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNK7_HUMAN
NC score	0.058607 (rank : 67)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	104	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNS2_HUMAN
NC score	0.052243 (rank : 68)	θ value	0.0193708 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.051807 (rank : 69)	θ value	0.0193708 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

NCOR2_MOUSE
NC score	0.042796 (rank : 70)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

KGP1B_HUMAN
NC score	0.040161 (rank : 71)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	921	Shared Neighborhood Hits	35
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.040156 (rank : 72)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	901	Shared Neighborhood Hits	36
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.039755 (rank : 73)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	922	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNB2_HUMAN
NC score	0.038897 (rank : 74)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	212	Shared Neighborhood Hits	34
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNN4_MOUSE
NC score	0.038761 (rank : 75)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNA4_HUMAN
NC score	0.034769 (rank : 76)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

NCOR2_HUMAN
NC score	0.031658 (rank : 77)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	870	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

KCNA4_MOUSE
NC score	0.030935 (rank : 78)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KGP2_HUMAN
NC score	0.028954 (rank : 79)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	1023	Shared Neighborhood Hits	30
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNN2_HUMAN
NC score	0.028771 (rank : 80)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.028748 (rank : 81)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KGP2_MOUSE
NC score	0.028199 (rank : 82)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	1029	Shared Neighborhood Hits	29
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

IL7RA_MOUSE
NC score	0.027233 (rank : 83)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

CKLF_HUMAN
NC score	0.026164 (rank : 84)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBR5, Q9UHM7, Q9UHN8, Q9UI41	Gene names	CKLF
Domain Architecture
Description	Chemokine-like factor (C32).

LARP1_HUMAN
NC score	0.018263 (rank : 85)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

IRK13_HUMAN
NC score	0.014596 (rank : 86)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

AGGF1_HUMAN
NC score	0.013791 (rank : 87)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

AF17_HUMAN
NC score	0.013402 (rank : 88)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	230	Shared Neighborhood Hits	5
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

ANR21_HUMAN
NC score	0.013257 (rank : 89)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	864	Shared Neighborhood Hits	7
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

PROM1_MOUSE
NC score	0.012987 (rank : 90)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

GP108_MOUSE
NC score	0.011742 (rank : 91)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WD0, Q8BXE9, Q925B1	Gene names	Gpr108, Lustr2
Domain Architecture	No domain graphic available
Description	Protein GPR108 precursor (Lung seven transmembrane receptor 2).

HD_MOUSE
NC score	0.011008 (rank : 92)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

POT15_HUMAN
NC score	0.010994 (rank : 93)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	893	Shared Neighborhood Hits	8
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

PROM1_HUMAN
NC score	0.010856 (rank : 94)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O43490	Gene names	PROM1, PROML1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133) (CD133 antigen).

TINF2_HUMAN
NC score	0.010810 (rank : 95)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSI4, Q9H904, Q9UHC2	Gene names	TINF2, TIN2
Domain Architecture	No domain graphic available
Description	TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2).

TP53B_MOUSE
NC score	0.010654 (rank : 96)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	644	Shared Neighborhood Hits	10
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

NAB2_MOUSE
NC score	0.010081 (rank : 97)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q61127	Gene names	Nab2
Domain Architecture
Description	NGFI-A-binding protein 2 (EGR-1-binding protein 2).

AP4E1_MOUSE
NC score	0.009701 (rank : 98)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

T2FA_HUMAN
NC score	0.009622 (rank : 99)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

LRCH2_HUMAN
NC score	0.008797 (rank : 100)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

LRCH2_MOUSE
NC score	0.008148 (rank : 101)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

FA35A_MOUSE
NC score	0.007902 (rank : 102)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UEN2	Gene names	Fam35a
Domain Architecture	No domain graphic available
Description	Protein FAM35A.

RFIP1_MOUSE
NC score	0.007494 (rank : 103)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	152	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

BCL7A_MOUSE
NC score	0.006859 (rank : 104)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CXE2, Q8C361, Q8C8M8, Q8VD15	Gene names	Bcl7a
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

ZHX3_HUMAN
NC score	0.006807 (rank : 105)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

TRI73_HUMAN
NC score	0.005835 (rank : 106)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	258	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.004809 (rank : 107)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

NDE1_HUMAN
NC score	0.004398 (rank : 108)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	823	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

MAP1B_HUMAN
NC score	0.003582 (rank : 109)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RPGR_MOUSE
NC score	0.003169 (rank : 110)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

TRI50_MOUSE
NC score	0.002536 (rank : 111)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

CEP35_HUMAN
NC score	0.002024 (rank : 112)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	811	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

RAI14_HUMAN
NC score	0.000816 (rank : 113)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	1367	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

APOA_HUMAN
NC score	-0.000148 (rank : 114)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	221	Shared Neighborhood Hits	2
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

MTR1L_HUMAN
NC score	-0.001526 (rank : 115)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	1180	Shared Neighborhood Hits	7
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

BRSK2_HUMAN
NC score	-0.002672 (rank : 116)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

MTR1L_MOUSE
NC score	-0.003327 (rank : 117)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	903	Shared Neighborhood Hits	3
SwissProt Accessions	O88495	Gene names	Gpr50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

OR2V2_HUMAN
NC score	-0.004130 (rank : 118)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	788	Shared Neighborhood Hits	2
SwissProt Accessions	Q96R30, Q6IFL6, Q8NGV1	Gene names	OR2V2, OR2V3
Domain Architecture
Description	Olfactory receptor 2V2 (Olfactory receptor OR5-3).