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Network neighborhood for query Sequence : HCN1_HUMAN

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HCN1_HUMAN
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.990656 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	172	Shared Neighborhood Hits	72
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.964151 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.974583 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	63
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	0 (rank : 5)	NC score	0.988166 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	0 (rank : 6)	NC score	0.988545 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	0 (rank : 7)	NC score	0.973135 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	0 (rank : 8)	NC score	0.970029 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA2_MOUSE
θ value	1.28137e-46 (rank : 9)	NC score	0.868271 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_MOUSE
θ value	2.04573e-44 (rank : 10)	NC score	0.856005 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	198	Shared Neighborhood Hits	50
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
θ value	1.32601e-43 (rank : 11)	NC score	0.857454 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	46
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	8.59492e-43 (rank : 12)	NC score	0.861301 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	1.79215e-40 (rank : 13)	NC score	0.854856 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

KCNH6_HUMAN
θ value	1.98146e-39 (rank : 14)	NC score	0.812057 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_MOUSE
θ value	2.19075e-38 (rank : 15)	NC score	0.808160 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
θ value	2.86122e-38 (rank : 16)	NC score	0.808720 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	158	Shared Neighborhood Hits	45
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
θ value	2.86122e-38 (rank : 17)	NC score	0.807813 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH5_HUMAN
θ value	4.88048e-38 (rank : 18)	NC score	0.798895 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	4.88048e-38 (rank : 19)	NC score	0.799174 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH7_HUMAN
θ value	5.96599e-36 (rank : 20)	NC score	0.802843 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH1_HUMAN
θ value	8.61488e-35 (rank : 21)	NC score	0.792658 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	8.61488e-35 (rank : 22)	NC score	0.792858 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

CNGB1_HUMAN
θ value	3.27365e-34 (rank : 23)	NC score	0.829583 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH4_HUMAN
θ value	3.61944e-33 (rank : 24)	NC score	0.798329 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	6.82597e-32 (rank : 25)	NC score	0.793221 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

CNGB3_MOUSE
θ value	1.16434e-31 (rank : 26)	NC score	0.836323 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	1.85889e-29 (rank : 27)	NC score	0.820264 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH3_HUMAN
θ value	2.42779e-29 (rank : 28)	NC score	0.781330 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	2.42779e-29 (rank : 29)	NC score	0.781208 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
θ value	1.87187e-05 (rank : 30)	NC score	0.301563 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KGP2_MOUSE
θ value	4.1701e-05 (rank : 31)	NC score	0.072640 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	1029	Shared Neighborhood Hits	36
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
θ value	9.29e-05 (rank : 32)	NC score	0.072576 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	1023	Shared Neighborhood Hits	37
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KAP3_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.233340 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	0.00175202 (rank : 34)	NC score	0.238765 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

LR37A_HUMAN
θ value	0.00175202 (rank : 35)	NC score	0.035332 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	720	Shared Neighborhood Hits	25
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

KGP1A_HUMAN
θ value	0.00228821 (rank : 36)	NC score	0.073335 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	901	Shared Neighborhood Hits	45
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00228821 (rank : 37)	NC score	0.073587 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	921	Shared Neighborhood Hits	45
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KAP2_HUMAN
θ value	0.00390308 (rank : 38)	NC score	0.242676 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	0.00390308 (rank : 39)	NC score	0.246775 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KGP1B_MOUSE
θ value	0.00390308 (rank : 40)	NC score	0.073591 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	922	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

RGS3_HUMAN
θ value	0.00665767 (rank : 41)	NC score	0.043498 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	1375	Shared Neighborhood Hits	29
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

KAP1_HUMAN
θ value	0.00869519 (rank : 42)	NC score	0.264236 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.00869519 (rank : 43)	NC score	0.261150 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

CCR3_MOUSE
θ value	0.0148317 (rank : 44)	NC score	0.016526 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

KAP0_MOUSE
θ value	0.0193708 (rank : 45)	NC score	0.271079 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

HIF1A_HUMAN
θ value	0.0736092 (rank : 46)	NC score	0.014898 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

DCP1B_HUMAN
θ value	0.125558 (rank : 47)	NC score	0.042134 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

EMSY_MOUSE
θ value	0.125558 (rank : 48)	NC score	0.041390 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

MDC1_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.035371 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

UBP10_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.021725 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

C8AP2_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.027030 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	548	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CTND2_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.017498 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DCC_MOUSE
θ value	0.365318 (rank : 53)	NC score	0.009452 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	896	Shared Neighborhood Hits	19
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

KCNS3_HUMAN
θ value	0.365318 (rank : 54)	NC score	0.016928 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

SAPS1_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.043069 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

PC11X_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.002206 (rank : 130)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

TARA_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.028283 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	1626	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZCH14_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.022275 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

RFX1_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.014379 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	256	Shared Neighborhood Hits	20
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

EMSY_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.034941 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

PRGC1_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.021331 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

SIG10_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.006173 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

TGON2_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.022766 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TP53B_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.025395 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	644	Shared Neighborhood Hits	29
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

KCNN3_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.017732 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	171	Shared Neighborhood Hits	16
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

R3HD2_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.047089 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RAPH1_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.018458 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	593	Shared Neighborhood Hits	29
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CAH11_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.009948 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75493, O60596, Q9UEC4	Gene names	CA11, CARP2
Domain Architecture
Description	Carbonic anhydrase-related protein 2 precursor (CARP-2) (CA-RP II) (CA-XI) (Carbonic anhydrase-related protein 11) (CARP XI) (CA-RP XI).

CT152_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.147806 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNQ3_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.038194 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.038492 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

BCL9_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.050173 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	1008	Shared Neighborhood Hits	32
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CJ012_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.015636 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	467	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

PP14A_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.039423 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

FBLN2_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.003543 (rank : 127)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

HRSL5_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.010568 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

MYPN_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.004871 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	418	Shared Neighborhood Hits	13
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

SCYL2_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.012864 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	603	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

ZN707_HUMAN
θ value	2.36792 (rank : 79)	NC score	-0.004003 (rank : 134)
Query Neighborhood Hits	120	Target Neighborhood Hits	741	Shared Neighborhood Hits	4
SwissProt Accessions	Q96C28	Gene names	ZNF707
Domain Architecture	No domain graphic available
Description	Zinc finger protein 707.

AFF1_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.014564 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	506	Shared Neighborhood Hits	26
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CAH11_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.008729 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O70354, Q8VEA9	Gene names	Ca11, Car11, Carp2
Domain Architecture
Description	Carbonic anhydrase-related protein 2 precursor (CARP-2) (CA-RP II) (CA-XI) (Carbonic anhydrase-related protein 11) (CARP XI) (CA-RP XI).

CTND2_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.016491 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

MAML1_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.028517 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NCOA2_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.031375 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA6_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.030254 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	1076	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NSD1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.008407 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	427	Shared Neighborhood Hits	16
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PRPF3_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.011373 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

RL4_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.012912 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

TAAR1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.002737 (rank : 129)
Query Neighborhood Hits	120	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

ANR41_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.003779 (rank : 126)
Query Neighborhood Hits	120	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

GCP6_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.008442 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

JADE2_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.009413 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MAML2_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.020931 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NCOA6_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.051719 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	1202	Shared Neighborhood Hits	50
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BSN_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.023079 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	1537	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

GLI2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.000150 (rank : 132)
Query Neighborhood Hits	120	Target Neighborhood Hits	971	Shared Neighborhood Hits	17
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

KCNQ2_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.029397 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

MLL3_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.022060 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	1399	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZN500_HUMAN
θ value	5.27518 (rank : 99)	NC score	-0.004326 (rank : 135)
Query Neighborhood Hits	120	Target Neighborhood Hits	746	Shared Neighborhood Hits	5
SwissProt Accessions	O60304, Q96CQ8, Q9BTG0	Gene names	ZNF500, KIAA0557
Domain Architecture
Description	Zinc finger protein 500.

CD248_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.002805 (rank : 128)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CT174_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.025272 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

ELL_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.006697 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

HMX3_MOUSE
θ value	6.88961 (rank : 103)	NC score	-0.000792 (rank : 133)
Query Neighborhood Hits	120	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

KAD6_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.013469 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KCNQ2_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.027998 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

NCOA2_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.017097 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

PKHA4_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.005892 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

RTP3_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.019112 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SRRM1_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.037265 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	966	Shared Neighborhood Hits	47
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ANK2_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.004718 (rank : 125)
Query Neighborhood Hits	120	Target Neighborhood Hits	1615	Shared Neighborhood Hits	38
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ATX2L_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.019309 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

DAXX_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.006847 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

HTRA4_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.031289 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

M3K1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.000365 (rank : 131)
Query Neighborhood Hits	120	Target Neighborhood Hits	952	Shared Neighborhood Hits	11
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

MPPD1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.006914 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O15442, Q8N361	Gene names	MPPED1, C22orf1, FAM1A
Domain Architecture
Description	Metallophosphoesterase domain-containing protein 1 (Adult brain protein 239) (239AB).

MPPD1_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.006909 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZG2, Q3TYC7	Gene names	Mpped1, D15Bwg0669e
Domain Architecture	No domain graphic available
Description	Metallophosphoesterase domain-containing protein 1.

NFH_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.025069 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	2247	Shared Neighborhood Hits	52
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RNC_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.011789 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	176	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TARSH_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.024720 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	768	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TTC28_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.008593 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

CT152_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.081805 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNK2_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.063490 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.063039 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.061148 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.059268 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.053767 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.062477 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.058591 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.065089 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.052653 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.097842 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

NACAM_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.052349 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRRT3_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.050570 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	998	Shared Neighborhood Hits	34
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RPGF4_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.054778 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.057258 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

HCN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	120	Target Neighborhood Hits	120	Shared Neighborhood Hits	120
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.990656 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	120	Target Neighborhood Hits	172	Shared Neighborhood Hits	72
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.988545 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	120	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.988166 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.974583 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	120	Target Neighborhood Hits	278	Shared Neighborhood Hits	63
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.973135 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	120	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.970029 (rank : 7)	θ value	0 (rank : 8)
Query Neighborhood Hits	120	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.964151 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	120	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
NC score	0.868271 (rank : 9)	θ value	1.28137e-46 (rank : 9)
Query Neighborhood Hits	120	Target Neighborhood Hits	86	Shared Neighborhood Hits	43
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.861301 (rank : 10)	θ value	8.59492e-43 (rank : 12)
Query Neighborhood Hits	120	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.857454 (rank : 11)	θ value	1.32601e-43 (rank : 11)
Query Neighborhood Hits	120	Target Neighborhood Hits	149	Shared Neighborhood Hits	46
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.856005 (rank : 12)	θ value	2.04573e-44 (rank : 10)
Query Neighborhood Hits	120	Target Neighborhood Hits	198	Shared Neighborhood Hits	50
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.854856 (rank : 13)	θ value	1.79215e-40 (rank : 13)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	43
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.836323 (rank : 14)	θ value	1.16434e-31 (rank : 26)
Query Neighborhood Hits	120	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
NC score	0.829583 (rank : 15)	θ value	3.27365e-34 (rank : 23)
Query Neighborhood Hits	120	Target Neighborhood Hits	222	Shared Neighborhood Hits	50
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
NC score	0.820264 (rank : 16)	θ value	1.85889e-29 (rank : 27)
Query Neighborhood Hits	120	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH6_HUMAN
NC score	0.812057 (rank : 17)	θ value	1.98146e-39 (rank : 14)
Query Neighborhood Hits	120	Target Neighborhood Hits	222	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.808720 (rank : 18)	θ value	2.86122e-38 (rank : 16)
Query Neighborhood Hits	120	Target Neighborhood Hits	158	Shared Neighborhood Hits	45
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.808160 (rank : 19)	θ value	2.19075e-38 (rank : 15)
Query Neighborhood Hits	120	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.807813 (rank : 20)	θ value	2.86122e-38 (rank : 17)
Query Neighborhood Hits	120	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.802843 (rank : 21)	θ value	5.96599e-36 (rank : 20)
Query Neighborhood Hits	120	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH5_MOUSE
NC score	0.799174 (rank : 22)	θ value	4.88048e-38 (rank : 19)
Query Neighborhood Hits	120	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.798895 (rank : 23)	θ value	4.88048e-38 (rank : 18)
Query Neighborhood Hits	120	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH4_HUMAN
NC score	0.798329 (rank : 24)	θ value	3.61944e-33 (rank : 24)
Query Neighborhood Hits	120	Target Neighborhood Hits	177	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
NC score	0.793221 (rank : 25)	θ value	6.82597e-32 (rank : 25)
Query Neighborhood Hits	120	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH1_MOUSE
NC score	0.792858 (rank : 26)	θ value	8.61488e-35 (rank : 22)
Query Neighborhood Hits	120	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.792658 (rank : 27)	θ value	8.61488e-35 (rank : 21)
Query Neighborhood Hits	120	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_HUMAN
NC score	0.781330 (rank : 28)	θ value	2.42779e-29 (rank : 28)
Query Neighborhood Hits	120	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.781208 (rank : 29)	θ value	2.42779e-29 (rank : 29)
Query Neighborhood Hits	120	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
NC score	0.301563 (rank : 30)	θ value	1.87187e-05 (rank : 30)
Query Neighborhood Hits	120	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.271079 (rank : 31)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.264236 (rank : 32)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	120	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.261150 (rank : 33)	θ value	0.00869519 (rank : 43)
Query Neighborhood Hits	120	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
NC score	0.246775 (rank : 34)	θ value	0.00390308 (rank : 39)
Query Neighborhood Hits	120	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.242676 (rank : 35)	θ value	0.00390308 (rank : 38)
Query Neighborhood Hits	120	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.238765 (rank : 36)	θ value	0.00175202 (rank : 34)
Query Neighborhood Hits	120	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.233340 (rank : 37)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	120	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.147806 (rank : 38)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	120	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNKH_HUMAN
NC score	0.097842 (rank : 39)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	120	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

CT152_HUMAN
NC score	0.081805 (rank : 40)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	120	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KGP1B_MOUSE
NC score	0.073591 (rank : 41)	θ value	0.00390308 (rank : 40)
Query Neighborhood Hits	120	Target Neighborhood Hits	922	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.073587 (rank : 42)	θ value	0.00228821 (rank : 37)
Query Neighborhood Hits	120	Target Neighborhood Hits	921	Shared Neighborhood Hits	45
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.073335 (rank : 43)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	120	Target Neighborhood Hits	901	Shared Neighborhood Hits	45
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_MOUSE
NC score	0.072640 (rank : 44)	θ value	4.1701e-05 (rank : 31)
Query Neighborhood Hits	120	Target Neighborhood Hits	1029	Shared Neighborhood Hits	36
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.072576 (rank : 45)	θ value	9.29e-05 (rank : 32)
Query Neighborhood Hits	120	Target Neighborhood Hits	1023	Shared Neighborhood Hits	37
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNKF_HUMAN
NC score	0.065089 (rank : 46)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	120	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.063490 (rank : 47)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	120	Target Neighborhood Hits	86	Shared Neighborhood Hits	17
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.063039 (rank : 48)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.062477 (rank : 49)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	120	Target Neighborhood Hits	79	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_HUMAN
NC score	0.061148 (rank : 50)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.059268 (rank : 51)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	120	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.058591 (rank : 52)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	120	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

RPGF4_MOUSE
NC score	0.057258 (rank : 53)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	120	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

RPGF4_HUMAN
NC score	0.054778 (rank : 54)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	120	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

KCNK4_HUMAN
NC score	0.053767 (rank : 55)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	120	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNKG_HUMAN
NC score	0.052653 (rank : 56)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	120	Target Neighborhood Hits	90	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

NACAM_MOUSE
NC score	0.052349 (rank : 57)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	120	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
NC score	0.051719 (rank : 58)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	120	Target Neighborhood Hits	1202	Shared Neighborhood Hits	50
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PRRT3_HUMAN
NC score	0.050570 (rank : 59)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	120	Target Neighborhood Hits	998	Shared Neighborhood Hits	34
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BCL9_HUMAN
NC score	0.050173 (rank : 60)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	120	Target Neighborhood Hits	1008	Shared Neighborhood Hits	32
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

R3HD2_MOUSE
NC score	0.047089 (rank : 61)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	120	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RGS3_HUMAN
NC score	0.043498 (rank : 62)	θ value	0.00665767 (rank : 41)
Query Neighborhood Hits	120	Target Neighborhood Hits	1375	Shared Neighborhood Hits	29
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SAPS1_HUMAN
NC score	0.043069 (rank : 63)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	120	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

DCP1B_HUMAN
NC score	0.042134 (rank : 64)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

EMSY_MOUSE
NC score	0.041390 (rank : 65)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	120	Target Neighborhood Hits	294	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

PP14A_MOUSE
NC score	0.039423 (rank : 66)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	120	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

KCNQ3_MOUSE
NC score	0.038492 (rank : 67)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	120	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.038194 (rank : 68)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

SRRM1_MOUSE
NC score	0.037265 (rank : 69)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	120	Target Neighborhood Hits	966	Shared Neighborhood Hits	47
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MDC1_MOUSE
NC score	0.035371 (rank : 70)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	120	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

LR37A_HUMAN
NC score	0.035332 (rank : 71)	θ value	0.00175202 (rank : 35)
Query Neighborhood Hits	120	Target Neighborhood Hits	720	Shared Neighborhood Hits	25
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

EMSY_HUMAN
NC score	0.034941 (rank : 72)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	120	Target Neighborhood Hits	296	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

NCOA2_HUMAN
NC score	0.031375 (rank : 73)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	120	Target Neighborhood Hits	281	Shared Neighborhood Hits	19
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

HTRA4_HUMAN
NC score	0.031289 (rank : 74)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	120	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

NCOA6_MOUSE
NC score	0.030254 (rank : 75)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	120	Target Neighborhood Hits	1076	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

KCNQ2_HUMAN
NC score	0.029397 (rank : 76)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	120	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

MAML1_MOUSE
NC score	0.028517 (rank : 77)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	120	Target Neighborhood Hits	279	Shared Neighborhood Hits	16
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

TARA_HUMAN
NC score	0.028283 (rank : 78)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	120	Target Neighborhood Hits	1626	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

KCNQ2_MOUSE
NC score	0.027998 (rank : 79)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	120	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

C8AP2_HUMAN
NC score	0.027030 (rank : 80)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	120	Target Neighborhood Hits	548	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

TP53B_MOUSE
NC score	0.025395 (rank : 81)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	120	Target Neighborhood Hits	644	Shared Neighborhood Hits	29
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CT174_HUMAN
NC score	0.025272 (rank : 82)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	120	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

NFH_MOUSE
NC score	0.025069 (rank : 83)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	120	Target Neighborhood Hits	2247	Shared Neighborhood Hits	52
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TARSH_HUMAN
NC score	0.024720 (rank : 84)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	120	Target Neighborhood Hits	768	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BSN_HUMAN
NC score	0.023079 (rank : 85)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	120	Target Neighborhood Hits	1537	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

TGON2_HUMAN
NC score	0.022766 (rank : 86)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	120	Target Neighborhood Hits	1037	Shared Neighborhood Hits	28
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZCH14_HUMAN
NC score	0.022275 (rank : 87)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	120	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

MLL3_MOUSE
NC score	0.022060 (rank : 88)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	120	Target Neighborhood Hits	1399	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UBP10_MOUSE
NC score	0.021725 (rank : 89)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	120	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

PRGC1_MOUSE
NC score	0.021331 (rank : 90)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	120	Target Neighborhood Hits	238	Shared Neighborhood Hits	11
SwissProt Accessions	O70343	Gene names	Ppargc1a, Pgc1, Pgc1a, Ppargc1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha).

MAML2_HUMAN
NC score	0.020931 (rank : 91)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	120	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

ATX2L_HUMAN
NC score	0.019309 (rank : 92)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	120	Target Neighborhood Hits	443	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

RTP3_MOUSE
NC score	0.019112 (rank : 93)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	120	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RAPH1_HUMAN
NC score	0.018458 (rank : 94)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	120	Target Neighborhood Hits	593	Shared Neighborhood Hits	29
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

KCNN3_MOUSE
NC score	0.017732 (rank : 95)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	120	Target Neighborhood Hits	171	Shared Neighborhood Hits	16
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

CTND2_HUMAN
NC score	0.017498 (rank : 96)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	120	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

NCOA2_MOUSE
NC score	0.017097 (rank : 97)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	120	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

KCNS3_HUMAN
NC score	0.016928 (rank : 98)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	120	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

CCR3_MOUSE
NC score	0.016526 (rank : 99)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	120	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

CTND2_MOUSE
NC score	0.016491 (rank : 100)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	120	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CJ012_HUMAN
NC score	0.015636 (rank : 101)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	120	Target Neighborhood Hits	467	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

HIF1A_HUMAN
NC score	0.014898 (rank : 102)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	120	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

AFF1_HUMAN
NC score	0.014564 (rank : 103)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	120	Target Neighborhood Hits	506	Shared Neighborhood Hits	26
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

RFX1_HUMAN
NC score	0.014379 (rank : 104)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	120	Target Neighborhood Hits	256	Shared Neighborhood Hits	20
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

KAD6_HUMAN
NC score	0.013469 (rank : 105)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	120	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RL4_HUMAN
NC score	0.012912 (rank : 106)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	120	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P36578, P39029, Q4VBR0, Q969Z9	Gene names	RPL4, RPL1
Domain Architecture
Description	60S ribosomal protein L4 (L1).

SCYL2_MOUSE
NC score	0.012864 (rank : 107)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	120	Target Neighborhood Hits	603	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

RNC_HUMAN
NC score	0.011789 (rank : 108)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	120	Target Neighborhood Hits	176	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

PRPF3_MOUSE
NC score	0.011373 (rank : 109)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	120	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

HRSL5_MOUSE
NC score	0.010568 (rank : 110)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	120	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

CAH11_HUMAN
NC score	0.009948 (rank : 111)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	120	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75493, O60596, Q9UEC4	Gene names	CA11, CARP2
Domain Architecture
Description	Carbonic anhydrase-related protein 2 precursor (CARP-2) (CA-RP II) (CA-XI) (Carbonic anhydrase-related protein 11) (CARP XI) (CA-RP XI).

DCC_MOUSE
NC score	0.009452 (rank : 112)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	120	Target Neighborhood Hits	896	Shared Neighborhood Hits	19
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

JADE2_MOUSE
NC score	0.009413 (rank : 113)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	120	Target Neighborhood Hits	560	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

CAH11_MOUSE
NC score	0.008729 (rank : 114)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	120	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O70354, Q8VEA9	Gene names	Ca11, Car11, Carp2
Domain Architecture
Description	Carbonic anhydrase-related protein 2 precursor (CARP-2) (CA-RP II) (CA-XI) (Carbonic anhydrase-related protein 11) (CARP XI) (CA-RP XI).

TTC28_HUMAN
NC score	0.008593 (rank : 115)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	120	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

GCP6_HUMAN
NC score	0.008442 (rank : 116)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	120	Target Neighborhood Hits	295	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

NSD1_HUMAN
NC score	0.008407 (rank : 117)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	120	Target Neighborhood Hits	427	Shared Neighborhood Hits	16
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MPPD1_HUMAN
NC score	0.006914 (rank : 118)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	120	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O15442, Q8N361	Gene names	MPPED1, C22orf1, FAM1A
Domain Architecture
Description	Metallophosphoesterase domain-containing protein 1 (Adult brain protein 239) (239AB).

MPPD1_MOUSE
NC score	0.006909 (rank : 119)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	120	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZG2, Q3TYC7	Gene names	Mpped1, D15Bwg0669e
Domain Architecture	No domain graphic available
Description	Metallophosphoesterase domain-containing protein 1.

DAXX_MOUSE
NC score	0.006847 (rank : 120)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	120	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

ELL_MOUSE
NC score	0.006697 (rank : 121)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	120	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	O08856	Gene names	Ell
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

SIG10_HUMAN
NC score	0.006173 (rank : 122)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	120	Target Neighborhood Hits	363	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

PKHA4_MOUSE
NC score	0.005892 (rank : 123)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	120	Target Neighborhood Hits	202	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

MYPN_HUMAN
NC score	0.004871 (rank : 124)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	120	Target Neighborhood Hits	418	Shared Neighborhood Hits	13
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

ANK2_HUMAN
NC score	0.004718 (rank : 125)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	120	Target Neighborhood Hits	1615	Shared Neighborhood Hits	38
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR41_HUMAN
NC score	0.003779 (rank : 126)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	120	Target Neighborhood Hits	332	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

FBLN2_HUMAN
NC score	0.003543 (rank : 127)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	120	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

CD248_HUMAN
NC score	0.002805 (rank : 128)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	120	Target Neighborhood Hits	679	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TAAR1_HUMAN
NC score	0.002737 (rank : 129)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	120	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

PC11X_HUMAN
NC score	0.002206 (rank : 130)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	120	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZA7, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5	Gene names	PCDH11X, PCDH11, PCDHX
Domain Architecture	No domain graphic available
Description	Protocadherin-11 X-linked precursor (Protocadherin-11) (Protocadherin on the X chromosome) (PCDH-X) (Protocadherin-S).

M3K1_MOUSE
NC score	0.000365 (rank : 131)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	120	Target Neighborhood Hits	952	Shared Neighborhood Hits	11
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

GLI2_HUMAN
NC score	0.000150 (rank : 132)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	120	Target Neighborhood Hits	971	Shared Neighborhood Hits	17
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

HMX3_MOUSE
NC score	-0.000792 (rank : 133)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	120	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	P42581	Gene names	Hmx3, Nkx-5.1, Nkx5-1
Domain Architecture
Description	Homeobox protein HMX3 (Homeobox protein Nkx-5.1).

ZN707_HUMAN
NC score	-0.004003 (rank : 134)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	120	Target Neighborhood Hits	741	Shared Neighborhood Hits	4
SwissProt Accessions	Q96C28	Gene names	ZNF707
Domain Architecture	No domain graphic available
Description	Zinc finger protein 707.

ZN500_HUMAN
NC score	-0.004326 (rank : 135)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	120	Target Neighborhood Hits	746	Shared Neighborhood Hits	5
SwissProt Accessions	O60304, Q96CQ8, Q9BTG0	Gene names	ZNF500, KIAA0557
Domain Architecture
Description	Zinc finger protein 500.