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Network neighborhood for query Sequence : KCNH1_HUMAN

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KCNH1_HUMAN
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNH1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	0 (rank : 2)	NC score	0.999421 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_HUMAN
θ value	0 (rank : 3)	NC score	0.996375 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	0 (rank : 4)	NC score	0.996498 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH8_HUMAN
θ value	1.28961e-139 (rank : 5)	NC score	0.968590 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
θ value	9.24197e-138 (rank : 6)	NC score	0.960695 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH3_HUMAN
θ value	5.24793e-133 (rank : 7)	NC score	0.961732 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	8.9516e-133 (rank : 8)	NC score	0.961757 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	133	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH4_HUMAN
θ value	1.09426e-130 (rank : 9)	NC score	0.963922 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH2_HUMAN
θ value	1.21265e-121 (rank : 10)	NC score	0.953508 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	3.52827e-121 (rank : 11)	NC score	0.953264 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
θ value	2.44908e-114 (rank : 12)	NC score	0.952357 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
θ value	1.13764e-111 (rank : 13)	NC score	0.951434 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

HCN1_HUMAN
θ value	8.61488e-35 (rank : 14)	NC score	0.792658 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	8.61488e-35 (rank : 15)	NC score	0.789071 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN4_HUMAN
θ value	3.27365e-34 (rank : 16)	NC score	0.772109 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	9.52487e-34 (rank : 17)	NC score	0.770212 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA2_MOUSE
θ value	2.12192e-33 (rank : 18)	NC score	0.808351 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

HCN2_HUMAN
θ value	2.34606e-32 (rank : 19)	NC score	0.765619 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	369	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	1.16434e-31 (rank : 20)	NC score	0.773819 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	1.16434e-31 (rank : 21)	NC score	0.786842 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	1.52067e-31 (rank : 22)	NC score	0.786878 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

CNGA1_HUMAN
θ value	1.6813e-30 (rank : 23)	NC score	0.796538 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	38
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	4.89182e-30 (rank : 24)	NC score	0.791882 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	7.80994e-28 (rank : 25)	NC score	0.789552 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	37
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
θ value	1.33217e-27 (rank : 26)	NC score	0.794199 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_HUMAN
θ value	7.0802e-21 (rank : 27)	NC score	0.730062 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_MOUSE
θ value	1.92812e-18 (rank : 28)	NC score	0.739798 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
θ value	8.95645e-16 (rank : 29)	NC score	0.718458 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	37
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
θ value	0.000786445 (rank : 30)	NC score	0.281701 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKA_HUMAN
θ value	0.00134147 (rank : 31)	NC score	0.210722 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	111	Shared Neighborhood Hits	50
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK3_HUMAN
θ value	0.00228821 (rank : 32)	NC score	0.212828 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNKG_HUMAN
θ value	0.00228821 (rank : 33)	NC score	0.202965 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK2_HUMAN
θ value	0.00298849 (rank : 34)	NC score	0.217054 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	0.00298849 (rank : 35)	NC score	0.216201 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_MOUSE
θ value	0.00509761 (rank : 36)	NC score	0.208411 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK9_HUMAN
θ value	0.0252991 (rank : 37)	NC score	0.184712 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	0.0252991 (rank : 38)	NC score	0.185004 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNKF_HUMAN
θ value	0.0252991 (rank : 39)	NC score	0.217452 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK6_HUMAN
θ value	0.0330416 (rank : 40)	NC score	0.206974 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	79	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KGP1B_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.045472 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	922	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNK1_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.160621 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
θ value	0.0431538 (rank : 43)	NC score	0.157090 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK4_HUMAN
θ value	0.0431538 (rank : 44)	NC score	0.197175 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCND3_HUMAN
θ value	0.0563607 (rank : 45)	NC score	0.078898 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.0563607 (rank : 46)	NC score	0.078894 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KGP1A_HUMAN
θ value	0.0736092 (rank : 47)	NC score	0.045243 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	901	Shared Neighborhood Hits	37
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.0736092 (rank : 48)	NC score	0.045347 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	921	Shared Neighborhood Hits	37
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KCNK4_MOUSE
θ value	0.0961366 (rank : 49)	NC score	0.185188 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCND1_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.080506 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
θ value	0.125558 (rank : 51)	NC score	0.085465 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND2_HUMAN
θ value	0.125558 (rank : 52)	NC score	0.079026 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.125558 (rank : 53)	NC score	0.079032 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNK5_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.156336 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

CYLN2_MOUSE
θ value	0.813845 (rank : 55)	NC score	0.004108 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	1002	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

KAP0_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.135163 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KCNS2_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.051851 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.051273 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KGP2_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.033925 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	1023	Shared Neighborhood Hits	29
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

RPGF2_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.016879 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

KAP0_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.146407 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KCNQ4_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.046235 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KGP2_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.033231 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	1029	Shared Neighborhood Hits	29
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

BATF_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.016218 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

BATF_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.014139 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

HUS1B_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.011217 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHY5, Q5T4Z2	Gene names	HUS1B
Domain Architecture	No domain graphic available
Description	Checkpoint protein HUS1B (hHUS1B).

KCNB1_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.041963 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.041959 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB2_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.043072 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	212	Shared Neighborhood Hits	37
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNV2_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.038361 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	137	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

NTBP1_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.006445 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	528	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

SYV_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.019009 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

TEX14_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.002664 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	13
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

BRD8_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.005979 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

KCNG4_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.042879 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNKD_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.117731 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

MAP1B_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.008350 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	977	Shared Neighborhood Hits	10
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SYV_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.015905 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

TRAF6_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.009410 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

KCNK7_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.103342 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

TMCC1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.003866 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

CO7A1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.001668 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	807	Shared Neighborhood Hits	6
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DBNL_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.003294 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

HS2ST_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.010440 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q7LGA3, O75036, Q8TAC5, Q9H441, Q9NUJ9	Gene names	HS2ST1, HS2ST, KIAA0448
Domain Architecture	No domain graphic available
Description	Heparan sulfate 2-O-sulfotransferase 1 (EC 2.8.2.-) (2-O- sulfotransferase) (2OST).

HS2ST_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.010426 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3H7, O88464, Q3TNP7, Q9JLK2	Gene names	Hs2st1, Hs2st
Domain Architecture	No domain graphic available
Description	Heparan sulfate 2-O-sulfotransferase 1 (EC 2.8.2.-) (2-O- sulfotransferase) (2OST) (2-OST).

KCNG2_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.040890 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNS1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.034719 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNT1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.038575 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNT1_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.034021 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

PAQR6_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.007746 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TCG5, Q3UTT0, Q8CF56	Gene names	Paqr6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

VDP_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.004835 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	469	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CAF1A_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.000711 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CSPG2_MOUSE
θ value	8.99809 (rank : 93)	NC score	-0.000126 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EVI1_HUMAN
θ value	8.99809 (rank : 94)	NC score	-0.004804 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

FGD4_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.000368 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

HTF4_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.005207 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

KCNF1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.040631 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNKD_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.098528 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

CT152_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.067146 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KAP1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.119908 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.117690 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.088348 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.090464 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.087436 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.090644 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCMA1_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.057210 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.057346 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNK7_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.080355 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNKC_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.092879 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.050848 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

Hits sorted by NC score

KCNH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
NC score	0.999421 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH5_MOUSE
NC score	0.996498 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.996375 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH8_HUMAN
NC score	0.968590 (rank : 5)	θ value	1.28961e-139 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
NC score	0.963922 (rank : 6)	θ value	1.09426e-130 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	177	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH3_MOUSE
NC score	0.961757 (rank : 7)	θ value	8.9516e-133 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	133	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
NC score	0.961732 (rank : 8)	θ value	5.24793e-133 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH6_HUMAN
NC score	0.960695 (rank : 9)	θ value	9.24197e-138 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.953508 (rank : 10)	θ value	1.21265e-121 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	158	Shared Neighborhood Hits	58
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.953264 (rank : 11)	θ value	3.52827e-121 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.952357 (rank : 12)	θ value	2.44908e-114 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.951434 (rank : 13)	θ value	1.13764e-111 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	107	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

CNGA2_MOUSE
NC score	0.808351 (rank : 14)	θ value	2.12192e-33 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA1_HUMAN
NC score	0.796538 (rank : 15)	θ value	1.6813e-30 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	149	Shared Neighborhood Hits	38
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_MOUSE
NC score	0.794199 (rank : 16)	θ value	1.33217e-27 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN1_HUMAN
NC score	0.792658 (rank : 17)	θ value	8.61488e-35 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	120	Shared Neighborhood Hits	36
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

CNGA1_MOUSE
NC score	0.791882 (rank : 18)	θ value	4.89182e-30 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.789552 (rank : 19)	θ value	7.80994e-28 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	125	Shared Neighborhood Hits	37
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN1_MOUSE
NC score	0.789071 (rank : 20)	θ value	8.61488e-35 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	172	Shared Neighborhood Hits	36
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN3_MOUSE
NC score	0.786878 (rank : 21)	θ value	1.52067e-31 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	36
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.786842 (rank : 22)	θ value	1.16434e-31 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.773819 (rank : 23)	θ value	1.16434e-31 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.772109 (rank : 24)	θ value	3.27365e-34 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	303	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.770212 (rank : 25)	θ value	9.52487e-34 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.765619 (rank : 26)	θ value	2.34606e-32 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	369	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGB3_MOUSE
NC score	0.739798 (rank : 27)	θ value	1.92812e-18 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
NC score	0.730062 (rank : 28)	θ value	7.0802e-21 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB1_HUMAN
NC score	0.718458 (rank : 29)	θ value	8.95645e-16 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	222	Shared Neighborhood Hits	37
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNKH_HUMAN
NC score	0.281701 (rank : 30)	θ value	0.000786445 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.217452 (rank : 31)	θ value	0.0252991 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.217054 (rank : 32)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.216201 (rank : 33)	θ value	0.00298849 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
NC score	0.212828 (rank : 34)	θ value	0.00228821 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	47
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.210722 (rank : 35)	θ value	0.00134147 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	111	Shared Neighborhood Hits	50
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK3_MOUSE
NC score	0.208411 (rank : 36)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK6_HUMAN
NC score	0.206974 (rank : 37)	θ value	0.0330416 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	79	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKG_HUMAN
NC score	0.202965 (rank : 38)	θ value	0.00228821 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	90	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK4_HUMAN
NC score	0.197175 (rank : 39)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK4_MOUSE
NC score	0.185188 (rank : 40)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK9_MOUSE
NC score	0.185004 (rank : 41)	θ value	0.0252991 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.184712 (rank : 42)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK1_HUMAN
NC score	0.160621 (rank : 43)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
NC score	0.157090 (rank : 44)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK5_HUMAN
NC score	0.156336 (rank : 45)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	102	Shared Neighborhood Hits	50
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KAP0_HUMAN
NC score	0.146407 (rank : 46)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.135163 (rank : 47)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.119908 (rank : 48)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNKD_MOUSE
NC score	0.117731 (rank : 49)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KAP1_MOUSE
NC score	0.117690 (rank : 50)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KCNK7_MOUSE
NC score	0.103342 (rank : 51)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKD_HUMAN
NC score	0.098528 (rank : 52)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKC_HUMAN
NC score	0.092879 (rank : 53)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KAP3_MOUSE
NC score	0.090644 (rank : 54)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP2_MOUSE
NC score	0.090464 (rank : 55)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.088348 (rank : 56)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_HUMAN
NC score	0.087436 (rank : 57)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KCND1_MOUSE
NC score	0.085465 (rank : 58)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	50
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.080506 (rank : 59)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNK7_HUMAN
NC score	0.080355 (rank : 60)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCND2_MOUSE
NC score	0.079032 (rank : 61)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	156	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.079026 (rank : 62)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
NC score	0.078898 (rank : 63)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
NC score	0.078894 (rank : 64)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	162	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

CT152_MOUSE
NC score	0.067146 (rank : 65)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCMA1_MOUSE
NC score	0.057346 (rank : 66)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.057210 (rank : 67)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	98	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNS2_HUMAN
NC score	0.051851 (rank : 68)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.051273 (rank : 69)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNQ3_MOUSE
NC score	0.050848 (rank : 70)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	98	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ4_HUMAN
NC score	0.046235 (rank : 71)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	136	Shared Neighborhood Hits	40
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KGP1B_MOUSE
NC score	0.045472 (rank : 72)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	922	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.045347 (rank : 73)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	921	Shared Neighborhood Hits	37
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.045243 (rank : 74)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	901	Shared Neighborhood Hits	37
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KCNB2_HUMAN
NC score	0.043072 (rank : 75)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	212	Shared Neighborhood Hits	37
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNG4_HUMAN
NC score	0.042879 (rank : 76)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNB1_HUMAN
NC score	0.041963 (rank : 77)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	169	Shared Neighborhood Hits	37
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.041959 (rank : 78)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	154	Shared Neighborhood Hits	37
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNG2_HUMAN
NC score	0.040890 (rank : 79)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNF1_HUMAN
NC score	0.040631 (rank : 80)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	109	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNT1_HUMAN
NC score	0.038575 (rank : 81)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNV2_HUMAN
NC score	0.038361 (rank : 82)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	137	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS1_MOUSE
NC score	0.034719 (rank : 83)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNT1_MOUSE
NC score	0.034021 (rank : 84)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KGP2_HUMAN
NC score	0.033925 (rank : 85)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	1023	Shared Neighborhood Hits	29
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.033231 (rank : 86)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	1029	Shared Neighborhood Hits	29
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

SYV_HUMAN
NC score	0.019009 (rank : 87)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

RPGF2_HUMAN
NC score	0.016879 (rank : 88)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	242	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

BATF_HUMAN
NC score	0.016218 (rank : 89)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q16520	Gene names	BATF
Domain Architecture
Description	ATF-like basic leucine zipper transcriptional factor B-ATF (SF-HT- activated gene 2) (SFA-2).

SYV_MOUSE
NC score	0.015905 (rank : 90)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

BATF_MOUSE
NC score	0.014139 (rank : 91)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	O35284	Gene names	Batf
Domain Architecture
Description	ATF-like basic leucine zipper transcription factor B-ATF.

HUS1B_HUMAN
NC score	0.011217 (rank : 92)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHY5, Q5T4Z2	Gene names	HUS1B
Domain Architecture	No domain graphic available
Description	Checkpoint protein HUS1B (hHUS1B).

HS2ST_HUMAN
NC score	0.010440 (rank : 93)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q7LGA3, O75036, Q8TAC5, Q9H441, Q9NUJ9	Gene names	HS2ST1, HS2ST, KIAA0448
Domain Architecture	No domain graphic available
Description	Heparan sulfate 2-O-sulfotransferase 1 (EC 2.8.2.-) (2-O- sulfotransferase) (2OST).

HS2ST_MOUSE
NC score	0.010426 (rank : 94)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3H7, O88464, Q3TNP7, Q9JLK2	Gene names	Hs2st1, Hs2st
Domain Architecture	No domain graphic available
Description	Heparan sulfate 2-O-sulfotransferase 1 (EC 2.8.2.-) (2-O- sulfotransferase) (2OST) (2-OST).

TRAF6_HUMAN
NC score	0.009410 (rank : 95)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

MAP1B_MOUSE
NC score	0.008350 (rank : 96)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	977	Shared Neighborhood Hits	10
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PAQR6_MOUSE
NC score	0.007746 (rank : 97)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6TCG5, Q3UTT0, Q8CF56	Gene names	Paqr6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

NTBP1_MOUSE
NC score	0.006445 (rank : 98)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	528	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

BRD8_HUMAN
NC score	0.005979 (rank : 99)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

HTF4_MOUSE
NC score	0.005207 (rank : 100)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

VDP_MOUSE
NC score	0.004835 (rank : 101)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	469	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CYLN2_MOUSE
NC score	0.004108 (rank : 102)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	1002	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

TMCC1_HUMAN
NC score	0.003866 (rank : 103)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

DBNL_MOUSE
NC score	0.003294 (rank : 104)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

TEX14_MOUSE
NC score	0.002664 (rank : 105)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	1333	Shared Neighborhood Hits	13
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CO7A1_HUMAN
NC score	0.001668 (rank : 106)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	807	Shared Neighborhood Hits	6
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CAF1A_HUMAN
NC score	0.000711 (rank : 107)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	750	Shared Neighborhood Hits	5
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

FGD4_HUMAN
NC score	0.000368 (rank : 108)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

CSPG2_MOUSE
NC score	-0.000126 (rank : 109)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	711	Shared Neighborhood Hits	4
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EVI1_HUMAN
NC score	-0.004804 (rank : 110)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.