Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : HCN3_MOUSE

For an explanation of this page, click here

HCN3_MOUSE
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.988545 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.985210 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.963131 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.973089 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	278	Shared Neighborhood Hits	56
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	0 (rank : 5)	NC score	0.996051 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	0 (rank : 7)	NC score	0.972427 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	0 (rank : 8)	NC score	0.970977 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA2_MOUSE
θ value	1.46607e-42 (rank : 9)	NC score	0.864173 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
θ value	1.05066e-40 (rank : 10)	NC score	0.858101 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
θ value	1.3722e-40 (rank : 11)	NC score	0.851691 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
θ value	8.89434e-40 (rank : 12)	NC score	0.851918 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
θ value	1.98146e-39 (rank : 13)	NC score	0.852999 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

KCNH6_HUMAN
θ value	1.98146e-39 (rank : 14)	NC score	0.809402 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	222	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
θ value	4.88048e-38 (rank : 15)	NC score	0.805358 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	158	Shared Neighborhood Hits	40
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	4.88048e-38 (rank : 16)	NC score	0.805018 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
θ value	1.9192e-34 (rank : 17)	NC score	0.803015 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH5_HUMAN
θ value	1.24399e-33 (rank : 18)	NC score	0.792903 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	1.6247e-33 (rank : 19)	NC score	0.793141 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

CNGB1_HUMAN
θ value	2.77131e-33 (rank : 20)	NC score	0.825816 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH4_HUMAN
θ value	4.72714e-33 (rank : 21)	NC score	0.794314 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH7_HUMAN
θ value	3.06405e-32 (rank : 22)	NC score	0.797947 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH1_HUMAN
θ value	1.52067e-31 (rank : 23)	NC score	0.786878 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	1.52067e-31 (rank : 24)	NC score	0.787051 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

CNGB3_MOUSE
θ value	5.40856e-29 (rank : 25)	NC score	0.833331 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	1.2049e-28 (rank : 26)	NC score	0.817682 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH8_HUMAN
θ value	1.33217e-27 (rank : 27)	NC score	0.787246 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH3_HUMAN
θ value	6.61148e-27 (rank : 28)	NC score	0.775874 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	1.47289e-26 (rank : 29)	NC score	0.775849 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_MOUSE
θ value	8.40245e-06 (rank : 30)	NC score	0.273066 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP0_HUMAN
θ value	1.09739e-05 (rank : 31)	NC score	0.301688 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KGP1A_HUMAN
θ value	0.00175202 (rank : 32)	NC score	0.074383 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	901	Shared Neighborhood Hits	53
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.00175202 (rank : 33)	NC score	0.074610 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	0.00175202 (rank : 34)	NC score	0.074608 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KAP1_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.263297 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.00509761 (rank : 36)	NC score	0.260271 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KGP2_HUMAN
θ value	0.00665767 (rank : 37)	NC score	0.072549 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	1023	Shared Neighborhood Hits	46
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
θ value	0.00869519 (rank : 38)	NC score	0.072548 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	1029	Shared Neighborhood Hits	45
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KAP2_HUMAN
θ value	0.0148317 (rank : 39)	NC score	0.235018 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_MOUSE
θ value	0.0148317 (rank : 40)	NC score	0.239150 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

CIZ1_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.050845 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

LIME1_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.048689 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H400, Q5JWJ2, Q6XYB3, Q9NX69	Gene names	LIME1, LIME
Domain Architecture	No domain graphic available
Description	Lck-interacting transmembrane adapter 1 (Lck-interacting membrane protein) (Lck-interacting molecule).

PDZD2_HUMAN
θ value	0.0961366 (rank : 43)	NC score	0.038685 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	772	Shared Neighborhood Hits	23
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

KAP3_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.228864 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

NACAM_MOUSE
θ value	0.125558 (rank : 45)	NC score	0.054326 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	54
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SEM6C_MOUSE
θ value	0.163984 (rank : 46)	NC score	0.017020 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

KAP3_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.223059 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

NUP53_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.045500 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

CCR3_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.015374 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

HTRA4_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.037408 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

MAST2_MOUSE
θ value	0.62314 (rank : 51)	NC score	0.009181 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1110	Shared Neighborhood Hits	21
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

CT152_MOUSE
θ value	0.813845 (rank : 52)	NC score	0.148070 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

NCOA6_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.050787 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	1202	Shared Neighborhood Hits	41
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ZN192_HUMAN
θ value	0.813845 (rank : 54)	NC score	-0.003406 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	789	Shared Neighborhood Hits	7
SwissProt Accessions	Q15776, Q4VAR1, Q4VAR2, Q4VAR3, Q9H4T1	Gene names	ZNF192
Domain Architecture
Description	Zinc finger protein 192 (LD5-1).

RIN3_MOUSE
θ value	1.06291 (rank : 55)	NC score	0.014619 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SC11A_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.007021 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SFPQ_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.008158 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TAAR1_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.003282 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

GSCR1_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.031985 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	674	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SYN1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.011563 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TR240_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.011546 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

AATK_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.004896 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	1243	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

FA47B_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.016552 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

PHLB1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.021076 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	1038	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SMCA2_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.005552 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	503	Shared Neighborhood Hits	13
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

WBP11_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.019701 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

CC020_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.010437 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8ND61, Q7L0U6, Q8NCP2, Q9H0I7	Gene names	C3orf20
Domain Architecture	No domain graphic available
Description	Protein C3orf20.

CIC_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.030393 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	992	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MAST3_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.007588 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	1128	Shared Neighborhood Hits	26
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MYLK_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.002450 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	1328	Shared Neighborhood Hits	17
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PRP2_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.023858 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SC24C_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.037034 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	34
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SMCA4_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.006107 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	597	Shared Neighborhood Hits	16
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SOX13_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.011592 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.014600 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	495	Shared Neighborhood Hits	16
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

WBP11_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.018789 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

COHA1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.005092 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	400	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DUS3L_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.007686 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

FBSH_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.013950 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

IRAK1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.002300 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	820	Shared Neighborhood Hits	17
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

NSMA2_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.007806 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PAK4_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.005607 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	1098	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

ADA12_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.003753 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	474	Shared Neighborhood Hits	17
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADM2_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.013618 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNK8	Gene names	Adm2, Am2
Domain Architecture	No domain graphic available
Description	ADM2 precursor (Intermedin) [Contains: Adrenomedullin-2 (Intermedin- long) (IMDL); Intermedin-short (IMDS)].

AKAP2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.006854 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ATG4D_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.004902 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

CECR2_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.023959 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

NIPA_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.008009 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

PHLB1_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.023055 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	678	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PROL4_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.017332 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q16378, Q8NFB3	Gene names	PRR4, LPRP, PROL4
Domain Architecture	No domain graphic available
Description	Proline-rich protein 4 precursor (Lacrimal proline-rich protein) (Nasopharyngeal carcinoma-associated proline-rich protein 4).

PRP40_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.003272 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	447	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

STRC_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.007408 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TM108_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.009318 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

UTX_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.007301 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

ZN219_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.001678 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	876	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

B4GT1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.018452 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

COHA1_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.006131 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	414	Shared Neighborhood Hits	12
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

EP300_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.013543 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	821	Shared Neighborhood Hits	28
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FOXM1_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.001427 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

KS6B1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.006149 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	850	Shared Neighborhood Hits	16
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.006150 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	849	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

MEF2D_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.027703 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

PRR3_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.008511 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

RENT2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.006520 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RIMB1_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.004988 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	22
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPKL1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.011319 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	708	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

RSNL2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.002882 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SAPS3_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.003702 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

TBC10_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.003525 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TTBK1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.008702 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

ZN217_HUMAN
θ value	8.99809 (rank : 111)	NC score	-0.000986 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	905	Shared Neighborhood Hits	14
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN516_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.010230 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	1197	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CT152_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.082235 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNK2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.061774 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.061341 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.059446 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.057547 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.051681 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.059912 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.056983 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.063647 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.050317 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.095211 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

PRRT3_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.052559 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	39
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RPGF4_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.053531 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.055988 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

Hits sorted by NC score

HCN3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.996051 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN1_HUMAN
NC score	0.988545 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
NC score	0.985210 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	49
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_MOUSE
NC score	0.973089 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	278	Shared Neighborhood Hits	56
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN4_HUMAN
NC score	0.972427 (rank : 6)	θ value	0 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	303	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.970977 (rank : 7)	θ value	0 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN2_HUMAN
NC score	0.963131 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
NC score	0.864173 (rank : 9)	θ value	1.46607e-42 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.858101 (rank : 10)	θ value	1.05066e-40 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.852999 (rank : 11)	θ value	1.98146e-39 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.851918 (rank : 12)	θ value	8.89434e-40 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.851691 (rank : 13)	θ value	1.3722e-40 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.833331 (rank : 14)	θ value	5.40856e-29 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
NC score	0.825816 (rank : 15)	θ value	2.77131e-33 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
NC score	0.817682 (rank : 16)	θ value	1.2049e-28 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH6_HUMAN
NC score	0.809402 (rank : 17)	θ value	1.98146e-39 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	222	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_HUMAN
NC score	0.805358 (rank : 18)	θ value	4.88048e-38 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	158	Shared Neighborhood Hits	40
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.805018 (rank : 19)	θ value	4.88048e-38 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	38
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH7_MOUSE
NC score	0.803015 (rank : 20)	θ value	1.9192e-34 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.797947 (rank : 21)	θ value	3.06405e-32 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH4_HUMAN
NC score	0.794314 (rank : 22)	θ value	4.72714e-33 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_MOUSE
NC score	0.793141 (rank : 23)	θ value	1.6247e-33 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.792903 (rank : 24)	θ value	1.24399e-33 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH8_HUMAN
NC score	0.787246 (rank : 25)	θ value	1.33217e-27 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH1_MOUSE
NC score	0.787051 (rank : 26)	θ value	1.52067e-31 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.786878 (rank : 27)	θ value	1.52067e-31 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_HUMAN
NC score	0.775874 (rank : 28)	θ value	6.61148e-27 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	148	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.775849 (rank : 29)	θ value	1.47289e-26 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
NC score	0.301688 (rank : 30)	θ value	1.09739e-05 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.273066 (rank : 31)	θ value	8.40245e-06 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	48	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.263297 (rank : 32)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.260271 (rank : 33)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
NC score	0.239150 (rank : 34)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.235018 (rank : 35)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.228864 (rank : 36)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.223059 (rank : 37)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.148070 (rank : 38)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

KCNKH_HUMAN
NC score	0.095211 (rank : 39)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

CT152_HUMAN
NC score	0.082235 (rank : 40)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KGP1B_HUMAN
NC score	0.074610 (rank : 41)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	921	Shared Neighborhood Hits	53
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
NC score	0.074608 (rank : 42)	θ value	0.00175202 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	922	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.074383 (rank : 43)	θ value	0.00175202 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	901	Shared Neighborhood Hits	53
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP2_HUMAN
NC score	0.072549 (rank : 44)	θ value	0.00665767 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	1023	Shared Neighborhood Hits	46
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
NC score	0.072548 (rank : 45)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	1029	Shared Neighborhood Hits	45
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KCNKF_HUMAN
NC score	0.063647 (rank : 46)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK2_HUMAN
NC score	0.061774 (rank : 47)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.061341 (rank : 48)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK6_HUMAN
NC score	0.059912 (rank : 49)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_HUMAN
NC score	0.059446 (rank : 50)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	13
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.057547 (rank : 51)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNKA_HUMAN
NC score	0.056983 (rank : 52)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

RPGF4_MOUSE
NC score	0.055988 (rank : 53)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

NACAM_MOUSE
NC score	0.054326 (rank : 54)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	54
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RPGF4_HUMAN
NC score	0.053531 (rank : 55)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

PRRT3_HUMAN
NC score	0.052559 (rank : 56)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	998	Shared Neighborhood Hits	39
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

KCNK4_HUMAN
NC score	0.051681 (rank : 57)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

CIZ1_HUMAN
NC score	0.050845 (rank : 58)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

NCOA6_HUMAN
NC score	0.050787 (rank : 59)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	1202	Shared Neighborhood Hits	41
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

KCNKG_HUMAN
NC score	0.050317 (rank : 60)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

LIME1_HUMAN
NC score	0.048689 (rank : 61)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H400, Q5JWJ2, Q6XYB3, Q9NX69	Gene names	LIME1, LIME
Domain Architecture	No domain graphic available
Description	Lck-interacting transmembrane adapter 1 (Lck-interacting membrane protein) (Lck-interacting molecule).

NUP53_HUMAN
NC score	0.045500 (rank : 62)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFH5, Q4ZFZ9, Q53S95, Q8TDJ1	Gene names	NUP35, MP44, NUP53
Domain Architecture	No domain graphic available
Description	Nucleoporin NUP53 (Nuclear pore complex protein Nup53) (Nucleoporin Nup35) (35 kDa nucleoporin) (Mitotic phosphoprotein 44) (MP-44).

PDZD2_HUMAN
NC score	0.038685 (rank : 63)	θ value	0.0961366 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	772	Shared Neighborhood Hits	23
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

HTRA4_HUMAN
NC score	0.037408 (rank : 64)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

SC24C_HUMAN
NC score	0.037034 (rank : 65)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	34
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

GSCR1_HUMAN
NC score	0.031985 (rank : 66)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	674	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CIC_HUMAN
NC score	0.030393 (rank : 67)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	992	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MEF2D_HUMAN
NC score	0.027703 (rank : 68)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

CECR2_HUMAN
NC score	0.023959 (rank : 69)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

PRP2_MOUSE
NC score	0.023858 (rank : 70)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	347	Shared Neighborhood Hits	19
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PHLB1_MOUSE
NC score	0.023055 (rank : 71)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	678	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_HUMAN
NC score	0.021076 (rank : 72)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	1038	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

WBP11_HUMAN
NC score	0.019701 (rank : 73)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	354	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
NC score	0.018789 (rank : 74)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

B4GT1_HUMAN
NC score	0.018452 (rank : 75)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

PROL4_HUMAN
NC score	0.017332 (rank : 76)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q16378, Q8NFB3	Gene names	PRR4, LPRP, PROL4
Domain Architecture	No domain graphic available
Description	Proline-rich protein 4 precursor (Lacrimal proline-rich protein) (Nasopharyngeal carcinoma-associated proline-rich protein 4).

SEM6C_MOUSE
NC score	0.017020 (rank : 77)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

FA47B_HUMAN
NC score	0.016552 (rank : 78)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	431	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

CCR3_MOUSE
NC score	0.015374 (rank : 79)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	781	Shared Neighborhood Hits	10
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

RIN3_MOUSE
NC score	0.014619 (rank : 80)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SOX13_MOUSE
NC score	0.014600 (rank : 81)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	495	Shared Neighborhood Hits	16
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

FBSH_HUMAN
NC score	0.013950 (rank : 82)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

ADM2_MOUSE
NC score	0.013618 (rank : 83)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TNK8	Gene names	Adm2, Am2
Domain Architecture	No domain graphic available
Description	ADM2 precursor (Intermedin) [Contains: Adrenomedullin-2 (Intermedin- long) (IMDL); Intermedin-short (IMDS)].

EP300_HUMAN
NC score	0.013543 (rank : 84)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	821	Shared Neighborhood Hits	28
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SOX13_HUMAN
NC score	0.011592 (rank : 85)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SYN1_HUMAN
NC score	0.011563 (rank : 86)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TR240_HUMAN
NC score	0.011546 (rank : 87)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

RPKL1_HUMAN
NC score	0.011319 (rank : 88)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	708	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

CC020_HUMAN
NC score	0.010437 (rank : 89)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8ND61, Q7L0U6, Q8NCP2, Q9H0I7	Gene names	C3orf20
Domain Architecture	No domain graphic available
Description	Protein C3orf20.

ZN516_MOUSE
NC score	0.010230 (rank : 90)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	1197	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

TM108_HUMAN
NC score	0.009318 (rank : 91)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MAST2_MOUSE
NC score	0.009181 (rank : 92)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	1110	Shared Neighborhood Hits	21
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TTBK1_HUMAN
NC score	0.008702 (rank : 93)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	1058	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PRR3_HUMAN
NC score	0.008511 (rank : 94)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P79522, Q5RJB5	Gene names	PRR3, CAT56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

SFPQ_HUMAN
NC score	0.008158 (rank : 95)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	986	Shared Neighborhood Hits	22
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

NIPA_HUMAN
NC score	0.008009 (rank : 96)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

NSMA2_MOUSE
NC score	0.007806 (rank : 97)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

DUS3L_HUMAN
NC score	0.007686 (rank : 98)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G46, Q96HM5, Q9BSU4, Q9H877, Q9NPR1	Gene names	DUS3L
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

MAST3_HUMAN
NC score	0.007588 (rank : 99)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	1128	Shared Neighborhood Hits	26
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

STRC_MOUSE
NC score	0.007408 (rank : 100)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

UTX_HUMAN
NC score	0.007301 (rank : 101)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

SC11A_MOUSE
NC score	0.007021 (rank : 102)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

AKAP2_HUMAN
NC score	0.006854 (rank : 103)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

RENT2_HUMAN
NC score	0.006520 (rank : 104)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	618	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

KS6B1_MOUSE
NC score	0.006150 (rank : 105)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	849	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.006149 (rank : 106)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	850	Shared Neighborhood Hits	16
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

COHA1_MOUSE
NC score	0.006131 (rank : 107)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	414	Shared Neighborhood Hits	12
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SMCA4_HUMAN
NC score	0.006107 (rank : 108)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	597	Shared Neighborhood Hits	16
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

PAK4_MOUSE
NC score	0.005607 (rank : 109)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	1098	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SMCA2_HUMAN
NC score	0.005552 (rank : 110)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	503	Shared Neighborhood Hits	13
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

COHA1_HUMAN
NC score	0.005092 (rank : 111)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	400	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

RIMB1_HUMAN
NC score	0.004988 (rank : 112)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	1479	Shared Neighborhood Hits	22
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ATG4D_HUMAN
NC score	0.004902 (rank : 113)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TL0	Gene names	ATG4D, APG4D, AUTL4
Domain Architecture	No domain graphic available
Description	Cysteine protease ATG4D (EC 3.4.22.-) (Autophagy-related protein 4 homolog D) (Autophagin-4) (Autophagy-related cysteine endopeptidase 4) (AUT-like 4 cysteine endopeptidase).

AATK_HUMAN
NC score	0.004896 (rank : 114)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	1243	Shared Neighborhood Hits	35
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ADA12_MOUSE
NC score	0.003753 (rank : 115)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	474	Shared Neighborhood Hits	17
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SAPS3_MOUSE
NC score	0.003702 (rank : 116)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

TBC10_HUMAN
NC score	0.003525 (rank : 117)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TAAR1_HUMAN
NC score	0.003282 (rank : 118)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	906	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

PRP40_MOUSE
NC score	0.003272 (rank : 119)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	447	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RSNL2_HUMAN
NC score	0.002882 (rank : 120)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

MYLK_HUMAN
NC score	0.002450 (rank : 121)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	1328	Shared Neighborhood Hits	17
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

IRAK1_HUMAN
NC score	0.002300 (rank : 122)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	820	Shared Neighborhood Hits	17
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

ZN219_HUMAN
NC score	0.001678 (rank : 123)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	876	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

FOXM1_HUMAN
NC score	0.001427 (rank : 124)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

ZN217_HUMAN
NC score	-0.000986 (rank : 125)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	905	Shared Neighborhood Hits	14
SwissProt Accessions	O75362	Gene names	ZNF217, ZABC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 217.

ZN192_HUMAN
NC score	-0.003406 (rank : 126)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	789	Shared Neighborhood Hits	7
SwissProt Accessions	Q15776, Q4VAR1, Q4VAR2, Q4VAR3, Q9H4T1	Gene names	ZNF192
Domain Architecture
Description	Zinc finger protein 192 (LD5-1).