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Network neighborhood for query Sequence : MEF2D_HUMAN

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MEF2D_HUMAN
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEF2D_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	170	Target Neighborhood Hits	170	Shared Neighborhood Hits	170
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2D_MOUSE
θ value	0 (rank : 2)	NC score	0.981474 (rank : 2)
Query Neighborhood Hits	170	Target Neighborhood Hits	146	Shared Neighborhood Hits	102
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2A_MOUSE
θ value	1.29861e-115 (rank : 3)	NC score	0.957492 (rank : 3)
Query Neighborhood Hits	170	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q60929	Gene names	Mef2a
Domain Architecture
Description	Myocyte-specific enhancer factor 2A.

MEF2C_MOUSE
θ value	4.1775e-114 (rank : 4)	NC score	0.946014 (rank : 5)
Query Neighborhood Hits	170	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

MEF2A_HUMAN
θ value	5.45601e-114 (rank : 5)	NC score	0.953939 (rank : 4)
Query Neighborhood Hits	170	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MEF2C_HUMAN
θ value	7.12574e-114 (rank : 6)	NC score	0.943717 (rank : 6)
Query Neighborhood Hits	170	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MEF2B_HUMAN
θ value	1.01529e-43 (rank : 7)	NC score	0.881486 (rank : 7)
Query Neighborhood Hits	170	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MEF2B_MOUSE
θ value	5.57106e-42 (rank : 8)	NC score	0.837552 (rank : 8)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

SRF_HUMAN
θ value	7.59969e-07 (rank : 9)	NC score	0.455735 (rank : 10)
Query Neighborhood Hits	170	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

SRF_MOUSE
θ value	7.59969e-07 (rank : 10)	NC score	0.458961 (rank : 9)
Query Neighborhood Hits	170	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM73	Gene names	Srf
Domain Architecture	No domain graphic available
Description	Serum response factor (SRF).

HNF1A_MOUSE
θ value	0.00298849 (rank : 11)	NC score	0.079341 (rank : 16)
Query Neighborhood Hits	170	Target Neighborhood Hits	212	Shared Neighborhood Hits	27
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

MLL2_HUMAN
θ value	0.00298849 (rank : 12)	NC score	0.078769 (rank : 17)
Query Neighborhood Hits	170	Target Neighborhood Hits	1788	Shared Neighborhood Hits	91
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CD248_HUMAN
θ value	0.00665767 (rank : 13)	NC score	0.045430 (rank : 49)
Query Neighborhood Hits	170	Target Neighborhood Hits	679	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ATX7_HUMAN
θ value	0.0148317 (rank : 14)	NC score	0.088705 (rank : 13)
Query Neighborhood Hits	170	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

MAML3_HUMAN
θ value	0.0193708 (rank : 15)	NC score	0.069645 (rank : 20)
Query Neighborhood Hits	170	Target Neighborhood Hits	323	Shared Neighborhood Hits	38
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

AFF1_HUMAN
θ value	0.0252991 (rank : 16)	NC score	0.054240 (rank : 33)
Query Neighborhood Hits	170	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NFRKB_MOUSE
θ value	0.0563607 (rank : 17)	NC score	0.090951 (rank : 12)
Query Neighborhood Hits	170	Target Neighborhood Hits	393	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

MAGC1_HUMAN
θ value	0.0736092 (rank : 18)	NC score	0.033206 (rank : 84)
Query Neighborhood Hits	170	Target Neighborhood Hits	431	Shared Neighborhood Hits	41
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

AFF2_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.057620 (rank : 29)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

GPR98_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.031810 (rank : 91)
Query Neighborhood Hits	170	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

HCN2_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.053789 (rank : 34)
Query Neighborhood Hits	170	Target Neighborhood Hits	369	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

EPN4_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.040657 (rank : 63)
Query Neighborhood Hits	170	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

SPR1A_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.050280 (rank : 40)
Query Neighborhood Hits	170	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

NFRKB_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.066902 (rank : 22)
Query Neighborhood Hits	170	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TXND2_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.041974 (rank : 60)
Query Neighborhood Hits	170	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UTX_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.038010 (rank : 71)
Query Neighborhood Hits	170	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

EMSY_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.050571 (rank : 39)
Query Neighborhood Hits	170	Target Neighborhood Hits	296	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EVI2B_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.074243 (rank : 19)
Query Neighborhood Hits	170	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

HCN4_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.046993 (rank : 45)
Query Neighborhood Hits	170	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HNF1A_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.057388 (rank : 30)
Query Neighborhood Hits	170	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

PCLO_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.057184 (rank : 31)
Query Neighborhood Hits	170	Target Neighborhood Hits	2046	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SPHK2_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.044702 (rank : 52)
Query Neighborhood Hits	170	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

CEL_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.030493 (rank : 98)
Query Neighborhood Hits	170	Target Neighborhood Hits	896	Shared Neighborhood Hits	66
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

FOXC1_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.024867 (rank : 118)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

SPR1A_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.043042 (rank : 58)
Query Neighborhood Hits	170	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TARSH_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.065107 (rank : 25)
Query Neighborhood Hits	170	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BAT2_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.087360 (rank : 14)
Query Neighborhood Hits	170	Target Neighborhood Hits	931	Shared Neighborhood Hits	78
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FOXP4_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.026977 (rank : 108)
Query Neighborhood Hits	170	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

LR37A_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.039358 (rank : 68)
Query Neighborhood Hits	170	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MINT_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.043327 (rank : 56)
Query Neighborhood Hits	170	Target Neighborhood Hits	1291	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PCOC1_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.013490 (rank : 146)
Query Neighborhood Hits	170	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

RBM6_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.030571 (rank : 97)
Query Neighborhood Hits	170	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SOX6_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.029850 (rank : 101)
Query Neighborhood Hits	170	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

ADA12_MOUSE
θ value	0.813845 (rank : 44)	NC score	0.023645 (rank : 121)
Query Neighborhood Hits	170	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BIN1_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.026776 (rank : 110)
Query Neighborhood Hits	170	Target Neighborhood Hits	335	Shared Neighborhood Hits	27
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CN004_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.045412 (rank : 50)
Query Neighborhood Hits	170	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

FBN2_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.009388 (rank : 157)
Query Neighborhood Hits	170	Target Neighborhood Hits	560	Shared Neighborhood Hits	6
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FOXC1_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.023696 (rank : 120)
Query Neighborhood Hits	170	Target Neighborhood Hits	208	Shared Neighborhood Hits	29
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

NFH_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.026759 (rank : 111)
Query Neighborhood Hits	170	Target Neighborhood Hits	2247	Shared Neighborhood Hits	85
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BAT2_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.093357 (rank : 11)
Query Neighborhood Hits	170	Target Neighborhood Hits	947	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

HCN2_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.043730 (rank : 53)
Query Neighborhood Hits	170	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

PRP1_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.065987 (rank : 24)
Query Neighborhood Hits	170	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

ATX1_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.035407 (rank : 76)
Query Neighborhood Hits	170	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

CUTL1_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.013761 (rank : 143)
Query Neighborhood Hits	170	Target Neighborhood Hits	1574	Shared Neighborhood Hits	34
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

GP179_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.033713 (rank : 82)
Query Neighborhood Hits	170	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

JUND_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.026148 (rank : 112)
Query Neighborhood Hits	170	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

K1802_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.043266 (rank : 57)
Query Neighborhood Hits	170	Target Neighborhood Hits	1378	Shared Neighborhood Hits	76
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PP16A_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.007330 (rank : 162)
Query Neighborhood Hits	170	Target Neighborhood Hits	318	Shared Neighborhood Hits	6
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ECM1_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.049036 (rank : 42)
Query Neighborhood Hits	170	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GAK18_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.032172 (rank : 87)
Query Neighborhood Hits	170	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK5_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.037634 (rank : 72)
Query Neighborhood Hits	170	Target Neighborhood Hits	429	Shared Neighborhood Hits	44
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

IPMK_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.032495 (rank : 86)
Query Neighborhood Hits	170	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

KBTB9_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.007581 (rank : 161)
Query Neighborhood Hits	170	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

MAML2_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.046156 (rank : 46)
Query Neighborhood Hits	170	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NCOA3_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.038633 (rank : 70)
Query Neighborhood Hits	170	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PO2F2_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.013645 (rank : 144)
Query Neighborhood Hits	170	Target Neighborhood Hits	379	Shared Neighborhood Hits	20
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RX_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.013510 (rank : 145)
Query Neighborhood Hits	170	Target Neighborhood Hits	423	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SPR1B_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.039011 (rank : 69)
Query Neighborhood Hits	170	Target Neighborhood Hits	395	Shared Neighborhood Hits	37
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

WEE1B_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.007050 (rank : 164)
Query Neighborhood Hits	170	Target Neighborhood Hits	836	Shared Neighborhood Hits	19
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

ARRD1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.031615 (rank : 92)
Query Neighborhood Hits	170	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

BCL9_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.055258 (rank : 32)
Query Neighborhood Hits	170	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BOLL_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.014921 (rank : 138)
Query Neighborhood Hits	170	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N9W6, Q969U3	Gene names	BOLL, BOULE
Domain Architecture
Description	Protein boule-like.

GAK12_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.033852 (rank : 81)
Query Neighborhood Hits	170	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

IL4RA_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.025895 (rank : 113)
Query Neighborhood Hits	170	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

K0552_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.025314 (rank : 116)
Query Neighborhood Hits	170	Target Neighborhood Hits	442	Shared Neighborhood Hits	12
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

NACAM_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.063313 (rank : 26)
Query Neighborhood Hits	170	Target Neighborhood Hits	1866	Shared Neighborhood Hits	104
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.082112 (rank : 15)
Query Neighborhood Hits	170	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCLO_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.052231 (rank : 36)
Query Neighborhood Hits	170	Target Neighborhood Hits	2275	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RAPH1_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.059252 (rank : 28)
Query Neighborhood Hits	170	Target Neighborhood Hits	593	Shared Neighborhood Hits	66
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TAB2_MOUSE
θ value	2.36792 (rank : 80)	NC score	0.020533 (rank : 128)
Query Neighborhood Hits	170	Target Neighborhood Hits	245	Shared Neighborhood Hits	19
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

ATBF1_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.015735 (rank : 136)
Query Neighborhood Hits	170	Target Neighborhood Hits	1841	Shared Neighborhood Hits	71
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BCOR_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.013879 (rank : 142)
Query Neighborhood Hits	170	Target Neighborhood Hits	609	Shared Neighborhood Hits	27
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

DACH1_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.025448 (rank : 115)
Query Neighborhood Hits	170	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

GAK11_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.034518 (rank : 79)
Query Neighborhood Hits	170	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.034538 (rank : 78)
Query Neighborhood Hits	170	Target Neighborhood Hits	415	Shared Neighborhood Hits	39
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HCN4_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.037208 (rank : 73)
Query Neighborhood Hits	170	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

IF4G2_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.031392 (rank : 93)
Query Neighborhood Hits	170	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IF4G2_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.030914 (rank : 95)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

LBN_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.021387 (rank : 125)
Query Neighborhood Hits	170	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

MAP1B_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.027344 (rank : 107)
Query Neighborhood Hits	170	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYO15_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.010797 (rank : 152)
Query Neighborhood Hits	170	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOA6_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.062219 (rank : 27)
Query Neighborhood Hits	170	Target Neighborhood Hits	1076	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFAT5_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.022107 (rank : 124)
Query Neighborhood Hits	170	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PCQAP_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.043586 (rank : 54)
Query Neighborhood Hits	170	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RGS3_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.031906 (rank : 89)
Query Neighborhood Hits	170	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SPR1B_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.040352 (rank : 64)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

US6NL_MOUSE
θ value	3.0926 (rank : 97)	NC score	0.017145 (rank : 132)
Query Neighborhood Hits	170	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

ZC3H3_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.023537 (rank : 122)
Query Neighborhood Hits	170	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ARI1B_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.035365 (rank : 77)
Query Neighborhood Hits	170	Target Neighborhood Hits	567	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CO039_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.030858 (rank : 96)
Query Neighborhood Hits	170	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FARP2_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.009797 (rank : 155)
Query Neighborhood Hits	170	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GTSE1_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.039993 (rank : 65)
Query Neighborhood Hits	170	Target Neighborhood Hits	245	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

MLL3_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.045730 (rank : 48)
Query Neighborhood Hits	170	Target Neighborhood Hits	1644	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RERE_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.045393 (rank : 51)
Query Neighborhood Hits	170	Target Neighborhood Hits	779	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RGS3_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.045968 (rank : 47)
Query Neighborhood Hits	170	Target Neighborhood Hits	1621	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TM108_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.036314 (rank : 75)
Query Neighborhood Hits	170	Target Neighborhood Hits	336	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZDHC8_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.009514 (rank : 156)
Query Neighborhood Hits	170	Target Neighborhood Hits	234	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN414_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.019883 (rank : 129)
Query Neighborhood Hits	170	Target Neighborhood Hits	548	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ARHGF_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.014190 (rank : 140)
Query Neighborhood Hits	170	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

BCL9_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.051983 (rank : 37)
Query Neighborhood Hits	170	Target Neighborhood Hits	770	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BNC1_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.006054 (rank : 168)
Query Neighborhood Hits	170	Target Neighborhood Hits	582	Shared Neighborhood Hits	5
SwissProt Accessions	O35914, O54886	Gene names	Bnc1, Bnc
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

CAC1B_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.006552 (rank : 166)
Query Neighborhood Hits	170	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CBP_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.043349 (rank : 55)
Query Neighborhood Hits	170	Target Neighborhood Hits	941	Shared Neighborhood Hits	81
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CGRE1_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.018659 (rank : 131)
Query Neighborhood Hits	170	Target Neighborhood Hits	354	Shared Neighborhood Hits	15
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

ECM1_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.028000 (rank : 103)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

EMSY_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.042436 (rank : 59)
Query Neighborhood Hits	170	Target Neighborhood Hits	294	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

GRIN1_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.025708 (rank : 114)
Query Neighborhood Hits	170	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

INVS_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.005265 (rank : 170)
Query Neighborhood Hits	170	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

NU214_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.030217 (rank : 99)
Query Neighborhood Hits	170	Target Neighborhood Hits	657	Shared Neighborhood Hits	45
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PENK_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.022159 (rank : 123)
Query Neighborhood Hits	170	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PHLPP_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.010858 (rank : 151)
Query Neighborhood Hits	170	Target Neighborhood Hits	604	Shared Neighborhood Hits	25
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SMR2C_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.041019 (rank : 62)
Query Neighborhood Hits	170	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

SMR2D_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.041770 (rank : 61)
Query Neighborhood Hits	170	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

WNK1_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.006896 (rank : 165)
Query Neighborhood Hits	170	Target Neighborhood Hits	1158	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AP1G1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.011428 (rank : 148)
Query Neighborhood Hits	170	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

ATX2L_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.033167 (rank : 85)
Query Neighborhood Hits	170	Target Neighborhood Hits	443	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

ATX2L_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.030095 (rank : 100)
Query Neighborhood Hits	170	Target Neighborhood Hits	401	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

CN037_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.027427 (rank : 106)
Query Neighborhood Hits	170	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

CUTL1_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.016356 (rank : 134)
Query Neighborhood Hits	170	Target Neighborhood Hits	1620	Shared Neighborhood Hits	47
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DDEF1_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.011295 (rank : 149)
Query Neighborhood Hits	170	Target Neighborhood Hits	592	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

EPN4_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.024511 (rank : 119)
Query Neighborhood Hits	170	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

ETV5_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.017070 (rank : 133)
Query Neighborhood Hits	170	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

HME1_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.007653 (rank : 159)
Query Neighborhood Hits	170	Target Neighborhood Hits	397	Shared Neighborhood Hits	17
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

IF4G1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.033494 (rank : 83)
Query Neighborhood Hits	170	Target Neighborhood Hits	534	Shared Neighborhood Hits	45
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

LAMP3_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.019131 (rank : 130)
Query Neighborhood Hits	170	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TST5, Q8C1F6	Gene names	Lamp3
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (CD208 antigen).

MB3L2_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.020857 (rank : 127)
Query Neighborhood Hits	170	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

MNT_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.027690 (rank : 105)
Query Neighborhood Hits	170	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PO121_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.026865 (rank : 109)
Query Neighborhood Hits	170	Target Neighborhood Hits	345	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

S13A2_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.007304 (rank : 163)
Query Neighborhood Hits	170	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q13183	Gene names	SLC13A2, NADC1, SDCT1
Domain Architecture
Description	Solute carrier family 13 member 2 (Renal sodium/dicarboxylate cotransporter) (Na(+)/dicarboxylate cotransporter 1) (NaDC-1).

SOX2_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.007622 (rank : 160)
Query Neighborhood Hits	170	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX6_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.021302 (rank : 126)
Query Neighborhood Hits	170	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

STML1_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.009864 (rank : 154)
Query Neighborhood Hits	170	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

SYNJ1_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.024892 (rank : 117)
Query Neighborhood Hits	170	Target Neighborhood Hits	516	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

AP1G1_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.010408 (rank : 153)
Query Neighborhood Hits	170	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

BTBD7_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.014815 (rank : 139)
Query Neighborhood Hits	170	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CBP_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.051508 (rank : 38)
Query Neighborhood Hits	170	Target Neighborhood Hits	1051	Shared Neighborhood Hits	91
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CD45_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.001801 (rank : 173)
Query Neighborhood Hits	170	Target Neighborhood Hits	243	Shared Neighborhood Hits	6
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

COR2A_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.002709 (rank : 172)
Query Neighborhood Hits	170	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

CRTC1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.036884 (rank : 74)
Query Neighborhood Hits	170	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

EP300_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.047059 (rank : 44)
Query Neighborhood Hits	170	Target Neighborhood Hits	821	Shared Neighborhood Hits	85
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FBX46_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.011112 (rank : 150)
Query Neighborhood Hits	170	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

GAK19_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.033908 (rank : 80)
Query Neighborhood Hits	170	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK2_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.031903 (rank : 90)
Query Neighborhood Hits	170	Target Neighborhood Hits	406	Shared Neighborhood Hits	38
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.031977 (rank : 88)
Query Neighborhood Hits	170	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GBF1_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.008740 (rank : 158)
Query Neighborhood Hits	170	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

HCN3_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.027703 (rank : 104)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

LSP1_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.012328 (rank : 147)
Query Neighborhood Hits	170	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

MINT_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.039992 (rank : 66)
Query Neighborhood Hits	170	Target Neighborhood Hits	1514	Shared Neighborhood Hits	82
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PO121_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.029239 (rank : 102)
Query Neighborhood Hits	170	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RBM19_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.005568 (rank : 169)
Query Neighborhood Hits	170	Target Neighborhood Hits	296	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

ROBO3_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.002840 (rank : 171)
Query Neighborhood Hits	170	Target Neighborhood Hits	524	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SC24D_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.013935 (rank : 141)
Query Neighborhood Hits	170	Target Neighborhood Hits	173	Shared Neighborhood Hits	25
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

TAB3_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.031069 (rank : 94)
Query Neighborhood Hits	170	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TCF7_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.015298 (rank : 137)
Query Neighborhood Hits	170	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF8_MOUSE
θ value	8.99809 (rank : 165)	NC score	-0.000288 (rank : 175)
Query Neighborhood Hits	170	Target Neighborhood Hits	1067	Shared Neighborhood Hits	22
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

TRI66_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.015885 (rank : 135)
Query Neighborhood Hits	170	Target Neighborhood Hits	491	Shared Neighborhood Hits	39
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

VINEX_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.006540 (rank : 167)
Query Neighborhood Hits	170	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

WIRE_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.048940 (rank : 43)
Query Neighborhood Hits	170	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.039906 (rank : 67)
Query Neighborhood Hits	170	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

ZN438_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.001673 (rank : 174)
Query Neighborhood Hits	170	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ATN1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.075323 (rank : 18)
Query Neighborhood Hits	170	Target Neighborhood Hits	676	Shared Neighborhood Hits	61
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CNOT3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.050065 (rank : 41)
Query Neighborhood Hits	170	Target Neighborhood Hits	425	Shared Neighborhood Hits	32
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MAGE1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.053037 (rank : 35)
Query Neighborhood Hits	170	Target Neighborhood Hits	1389	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

WASIP_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.066544 (rank : 23)
Query Neighborhood Hits	170	Target Neighborhood Hits	458	Shared Neighborhood Hits	55
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.067865 (rank : 21)
Query Neighborhood Hits	170	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

Hits sorted by NC score

MEF2D_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	170	Target Neighborhood Hits	170	Shared Neighborhood Hits	170
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2D_MOUSE
NC score	0.981474 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	170	Target Neighborhood Hits	146	Shared Neighborhood Hits	102
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2A_MOUSE
NC score	0.957492 (rank : 3)	θ value	1.29861e-115 (rank : 3)
Query Neighborhood Hits	170	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	Q60929	Gene names	Mef2a
Domain Architecture
Description	Myocyte-specific enhancer factor 2A.

MEF2A_HUMAN
NC score	0.953939 (rank : 4)	θ value	5.45601e-114 (rank : 5)
Query Neighborhood Hits	170	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q02078, O43814, Q14223, Q14224, Q96D14	Gene names	MEF2A, MEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1).

MEF2C_MOUSE
NC score	0.946014 (rank : 5)	θ value	4.1775e-114 (rank : 4)
Query Neighborhood Hits	170	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CFN5, Q8R0H1, Q9D7L0, Q9QW20	Gene names	Mef2c
Domain Architecture	No domain graphic available
Description	Myocyte-specific enhancer factor 2C.

MEF2C_HUMAN
NC score	0.943717 (rank : 6)	θ value	7.12574e-114 (rank : 6)
Query Neighborhood Hits	170	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q06413	Gene names	MEF2C
Domain Architecture
Description	Myocyte-specific enhancer factor 2C.

MEF2B_HUMAN
NC score	0.881486 (rank : 7)	θ value	1.01529e-43 (rank : 7)
Query Neighborhood Hits	170	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MEF2B_MOUSE
NC score	0.837552 (rank : 8)	θ value	5.57106e-42 (rank : 8)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

SRF_MOUSE
NC score	0.458961 (rank : 9)	θ value	7.59969e-07 (rank : 10)
Query Neighborhood Hits	170	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JM73	Gene names	Srf
Domain Architecture	No domain graphic available
Description	Serum response factor (SRF).

SRF_HUMAN
NC score	0.455735 (rank : 10)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	170	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

BAT2_MOUSE
NC score	0.093357 (rank : 11)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	170	Target Neighborhood Hits	947	Shared Neighborhood Hits	79
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NFRKB_MOUSE
NC score	0.090951 (rank : 12)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	170	Target Neighborhood Hits	393	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ATX7_HUMAN
NC score	0.088705 (rank : 13)	θ value	0.0148317 (rank : 14)
Query Neighborhood Hits	170	Target Neighborhood Hits	351	Shared Neighborhood Hits	40
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BAT2_HUMAN
NC score	0.087360 (rank : 14)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	170	Target Neighborhood Hits	931	Shared Neighborhood Hits	78
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCOA6_HUMAN
NC score	0.082112 (rank : 15)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	170	Target Neighborhood Hits	1202	Shared Neighborhood Hits	108
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

HNF1A_MOUSE
NC score	0.079341 (rank : 16)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	170	Target Neighborhood Hits	212	Shared Neighborhood Hits	27
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

MLL2_HUMAN
NC score	0.078769 (rank : 17)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	170	Target Neighborhood Hits	1788	Shared Neighborhood Hits	91
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ATN1_HUMAN
NC score	0.075323 (rank : 18)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	170	Target Neighborhood Hits	676	Shared Neighborhood Hits	61
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

EVI2B_MOUSE
NC score	0.074243 (rank : 19)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	170	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

MAML3_HUMAN
NC score	0.069645 (rank : 20)	θ value	0.0193708 (rank : 15)
Query Neighborhood Hits	170	Target Neighborhood Hits	323	Shared Neighborhood Hits	38
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

WASIP_MOUSE
NC score	0.067865 (rank : 21)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	170	Target Neighborhood Hits	392	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

NFRKB_HUMAN
NC score	0.066902 (rank : 22)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	170	Target Neighborhood Hits	211	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

WASIP_HUMAN
NC score	0.066544 (rank : 23)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	170	Target Neighborhood Hits	458	Shared Neighborhood Hits	55
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRP1_HUMAN
NC score	0.065987 (rank : 24)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	170	Target Neighborhood Hits	385	Shared Neighborhood Hits	57
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TARSH_HUMAN
NC score	0.065107 (rank : 25)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	170	Target Neighborhood Hits	768	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

NACAM_MOUSE
NC score	0.063313 (rank : 26)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	170	Target Neighborhood Hits	1866	Shared Neighborhood Hits	104
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_MOUSE
NC score	0.062219 (rank : 27)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	170	Target Neighborhood Hits	1076	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

RAPH1_HUMAN
NC score	0.059252 (rank : 28)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	170	Target Neighborhood Hits	593	Shared Neighborhood Hits	66
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AFF2_HUMAN
NC score	0.057620 (rank : 29)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	24
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

HNF1A_HUMAN
NC score	0.057388 (rank : 30)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	170	Target Neighborhood Hits	193	Shared Neighborhood Hits	24
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

PCLO_HUMAN
NC score	0.057184 (rank : 31)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	170	Target Neighborhood Hits	2046	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

BCL9_HUMAN
NC score	0.055258 (rank : 32)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	170	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

AFF1_HUMAN
NC score	0.054240 (rank : 33)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	170	Target Neighborhood Hits	506	Shared Neighborhood Hits	42
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

HCN2_HUMAN
NC score	0.053789 (rank : 34)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	170	Target Neighborhood Hits	369	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

MAGE1_HUMAN
NC score	0.053037 (rank : 35)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	170	Target Neighborhood Hits	1389	Shared Neighborhood Hits	94
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PCLO_MOUSE
NC score	0.052231 (rank : 36)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	170	Target Neighborhood Hits	2275	Shared Neighborhood Hits	110
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

BCL9_MOUSE
NC score	0.051983 (rank : 37)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	170	Target Neighborhood Hits	770	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CBP_MOUSE
NC score	0.051508 (rank : 38)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	170	Target Neighborhood Hits	1051	Shared Neighborhood Hits	91
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

EMSY_HUMAN
NC score	0.050571 (rank : 39)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	170	Target Neighborhood Hits	296	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

SPR1A_HUMAN
NC score	0.050280 (rank : 40)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	170	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

CNOT3_HUMAN
NC score	0.050065 (rank : 41)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	170	Target Neighborhood Hits	425	Shared Neighborhood Hits	32
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ECM1_HUMAN
NC score	0.049036 (rank : 42)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	170	Target Neighborhood Hits	182	Shared Neighborhood Hits	24
SwissProt Accessions	Q16610	Gene names	ECM1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

WIRE_HUMAN
NC score	0.048940 (rank : 43)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	170	Target Neighborhood Hits	329	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

EP300_HUMAN
NC score	0.047059 (rank : 44)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	170	Target Neighborhood Hits	821	Shared Neighborhood Hits	85
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HCN4_MOUSE
NC score	0.046993 (rank : 45)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	170	Target Neighborhood Hits	284	Shared Neighborhood Hits	39
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MAML2_HUMAN
NC score	0.046156 (rank : 46)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	170	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

RGS3_MOUSE
NC score	0.045968 (rank : 47)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	170	Target Neighborhood Hits	1621	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MLL3_HUMAN
NC score	0.045730 (rank : 48)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	170	Target Neighborhood Hits	1644	Shared Neighborhood Hits	73
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CD248_HUMAN
NC score	0.045430 (rank : 49)	θ value	0.00665767 (rank : 13)
Query Neighborhood Hits	170	Target Neighborhood Hits	679	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CN004_HUMAN
NC score	0.045412 (rank : 50)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	170	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1B7, Q8NDQ2, Q96JG2, Q9H3I7	Gene names	C14orf4, KIAA1865
Domain Architecture	No domain graphic available
Description	Protein C14orf4.

RERE_HUMAN
NC score	0.045393 (rank : 51)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	170	Target Neighborhood Hits	779	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPHK2_MOUSE
NC score	0.044702 (rank : 52)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	170	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

HCN2_MOUSE
NC score	0.043730 (rank : 53)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	170	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

PCQAP_HUMAN
NC score	0.043586 (rank : 54)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	170	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CBP_HUMAN
NC score	0.043349 (rank : 55)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	170	Target Neighborhood Hits	941	Shared Neighborhood Hits	81
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MINT_HUMAN
NC score	0.043327 (rank : 56)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	170	Target Neighborhood Hits	1291	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

K1802_HUMAN
NC score	0.043266 (rank : 57)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	170	Target Neighborhood Hits	1378	Shared Neighborhood Hits	76
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SPR1A_MOUSE
NC score	0.043042 (rank : 58)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	170	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

EMSY_MOUSE
NC score	0.042436 (rank : 59)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	170	Target Neighborhood Hits	294	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

TXND2_HUMAN
NC score	0.041974 (rank : 60)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	170	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SMR2D_MOUSE
NC score	0.041770 (rank : 61)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	170	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O35979	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform delta precursor (Salivary protein MSG2, isoform delta).

SMR2C_MOUSE
NC score	0.041019 (rank : 62)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	170	Target Neighborhood Hits	43	Shared Neighborhood Hits	8
SwissProt Accessions	O35985	Gene names	Smr2, Msg2, Vcs2
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 2, isoform gamma precursor (Salivary protein MSG2, isoform gamma).

EPN4_MOUSE
NC score	0.040657 (rank : 63)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	170	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

SPR1B_HUMAN
NC score	0.040352 (rank : 64)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	170	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

GTSE1_MOUSE
NC score	0.039993 (rank : 65)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	170	Target Neighborhood Hits	245	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

MINT_MOUSE
NC score	0.039992 (rank : 66)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	170	Target Neighborhood Hits	1514	Shared Neighborhood Hits	82
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

WIRE_MOUSE
NC score	0.039906 (rank : 67)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	170	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

LR37A_HUMAN
NC score	0.039358 (rank : 68)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	170	Target Neighborhood Hits	720	Shared Neighborhood Hits	54
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SPR1B_MOUSE
NC score	0.039011 (rank : 69)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	170	Target Neighborhood Hits	395	Shared Neighborhood Hits	37
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

NCOA3_MOUSE
NC score	0.038633 (rank : 70)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	170	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

UTX_HUMAN
NC score	0.038010 (rank : 71)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	170	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

GAK5_HUMAN
NC score	0.037634 (rank : 72)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	170	Target Neighborhood Hits	429	Shared Neighborhood Hits	44
SwissProt Accessions	P62684	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K113 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HCN4_HUMAN
NC score	0.037208 (rank : 73)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	170	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CRTC1_MOUSE
NC score	0.036884 (rank : 74)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	170	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

TM108_MOUSE
NC score	0.036314 (rank : 75)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	170	Target Neighborhood Hits	336	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ATX1_MOUSE
NC score	0.035407 (rank : 76)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	170	Target Neighborhood Hits	264	Shared Neighborhood Hits	32
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ARI1B_HUMAN
NC score	0.035365 (rank : 77)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	170	Target Neighborhood Hits	567	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

GAK4_HUMAN
NC score	0.034538 (rank : 78)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	170	Target Neighborhood Hits	415	Shared Neighborhood Hits	39
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK11_HUMAN
NC score	0.034518 (rank : 79)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	170	Target Neighborhood Hits	409	Shared Neighborhood Hits	39
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK19_HUMAN
NC score	0.033908 (rank : 80)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	170	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

GAK12_HUMAN
NC score	0.033852 (rank : 81)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	170	Target Neighborhood Hits	374	Shared Neighborhood Hits	37
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GP179_HUMAN
NC score	0.033713 (rank : 82)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	170	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

IF4G1_MOUSE
NC score	0.033494 (rank : 83)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	170	Target Neighborhood Hits	534	Shared Neighborhood Hits	45
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

MAGC1_HUMAN
NC score	0.033206 (rank : 84)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	170	Target Neighborhood Hits	431	Shared Neighborhood Hits	41
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

ATX2L_HUMAN
NC score	0.033167 (rank : 85)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	170	Target Neighborhood Hits	443	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

IPMK_HUMAN
NC score	0.032495 (rank : 86)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	170	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

GAK18_HUMAN
NC score	0.032172 (rank : 87)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	170	Target Neighborhood Hits	116	Shared Neighborhood Hits	22
SwissProt Accessions	P62690	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.23 provirus ancestral Gag polyprotein (Gag polyprotein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
NC score	0.031977 (rank : 88)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	170	Target Neighborhood Hits	392	Shared Neighborhood Hits	38
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

RGS3_HUMAN
NC score	0.031906 (rank : 89)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	170	Target Neighborhood Hits	1375	Shared Neighborhood Hits	82
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GAK2_HUMAN
NC score	0.031903 (rank : 90)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	170	Target Neighborhood Hits	406	Shared Neighborhood Hits	38
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GPR98_HUMAN
NC score	0.031810 (rank : 91)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	170	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ARRD1_MOUSE
NC score	0.031615 (rank : 92)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	170	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q99KN1, Q3TDT6, Q8VEG7	Gene names	Arrdc1
Domain Architecture	No domain graphic available
Description	Arrestin domain-containing protein 1.

IF4G2_HUMAN
NC score	0.031392 (rank : 93)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	170	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

TAB3_MOUSE
NC score	0.031069 (rank : 94)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	170	Target Neighborhood Hits	273	Shared Neighborhood Hits	37
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

IF4G2_MOUSE
NC score	0.030914 (rank : 95)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	170	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

CO039_MOUSE
NC score	0.030858 (rank : 96)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	170	Target Neighborhood Hits	445	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

RBM6_HUMAN
NC score	0.030571 (rank : 97)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	170	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

CEL_HUMAN
NC score	0.030493 (rank : 98)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	170	Target Neighborhood Hits	896	Shared Neighborhood Hits	66
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NU214_HUMAN
NC score	0.030217 (rank : 99)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	170	Target Neighborhood Hits	657	Shared Neighborhood Hits	45
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ATX2L_MOUSE
NC score	0.030095 (rank : 100)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	170	Target Neighborhood Hits	401	Shared Neighborhood Hits	47
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

SOX6_MOUSE
NC score	0.029850 (rank : 101)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	170	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

PO121_HUMAN
NC score	0.029239 (rank : 102)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	170	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

ECM1_MOUSE
NC score	0.028000 (rank : 103)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	170	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

HCN3_MOUSE
NC score	0.027703 (rank : 104)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	170	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

MNT_MOUSE
NC score	0.027690 (rank : 105)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	170	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

CN037_MOUSE
NC score	0.027427 (rank : 106)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	170	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

MAP1B_MOUSE
NC score	0.027344 (rank : 107)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	170	Target Neighborhood Hits	977	Shared Neighborhood Hits	49
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

FOXP4_HUMAN
NC score	0.026977 (rank : 108)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	170	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

PO121_MOUSE
NC score	0.026865 (rank : 109)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	170	Target Neighborhood Hits	345	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

BIN1_HUMAN
NC score	0.026776 (rank : 110)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	170	Target Neighborhood Hits	335	Shared Neighborhood Hits	27
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

NFH_MOUSE
NC score	0.026759 (rank : 111)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	170	Target Neighborhood Hits	2247	Shared Neighborhood Hits	85
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

JUND_MOUSE
NC score	0.026148 (rank : 112)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	170	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

IL4RA_MOUSE
NC score	0.025895 (rank : 113)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	170	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

GRIN1_MOUSE
NC score	0.025708 (rank : 114)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	170	Target Neighborhood Hits	337	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DACH1_MOUSE
NC score	0.025448 (rank : 115)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	170	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

K0552_HUMAN
NC score	0.025314 (rank : 116)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	170	Target Neighborhood Hits	442	Shared Neighborhood Hits	12
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

SYNJ1_MOUSE
NC score	0.024892 (rank : 117)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	170	Target Neighborhood Hits	516	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

FOXC1_MOUSE
NC score	0.024867 (rank : 118)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	170	Target Neighborhood Hits	218	Shared Neighborhood Hits	30
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

EPN4_HUMAN
NC score	0.024511 (rank : 119)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	170	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

FOXC1_HUMAN
NC score	0.023696 (rank : 120)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	170	Target Neighborhood Hits	208	Shared Neighborhood Hits	29
SwissProt Accessions	Q12948, Q86UP7, Q9BYM1, Q9NUE5, Q9UDD0, Q9UP06	Gene names	FOXC1, FKHL7, FREAC3
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3).

ADA12_MOUSE
NC score	0.023645 (rank : 121)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	170	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ZC3H3_MOUSE
NC score	0.023537 (rank : 122)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	170	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

PENK_HUMAN
NC score	0.022159 (rank : 123)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	170	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

NFAT5_HUMAN
NC score	0.022107 (rank : 124)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	170	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

LBN_MOUSE
NC score	0.021387 (rank : 125)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	170	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K1G2, Q8BRF3	Gene names	Evc2, Lbn
Domain Architecture	No domain graphic available
Description	Limbin.

SOX6_HUMAN
NC score	0.021302 (rank : 126)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	170	Target Neighborhood Hits	332	Shared Neighborhood Hits	22
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

MB3L2_HUMAN
NC score	0.020857 (rank : 127)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	170	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

TAB2_MOUSE
NC score	0.020533 (rank : 128)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	170	Target Neighborhood Hits	245	Shared Neighborhood Hits	19
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

ZN414_HUMAN
NC score	0.019883 (rank : 129)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	170	Target Neighborhood Hits	548	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

LAMP3_MOUSE
NC score	0.019131 (rank : 130)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	170	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TST5, Q8C1F6	Gene names	Lamp3
Domain Architecture	No domain graphic available
Description	Lysosome-associated membrane glycoprotein 3 precursor (LAMP-3) (Lysosomal-associated membrane protein 3) (DC-lysosome-associated membrane glycoprotein) (DC LAMP) (CD208 antigen).

CGRE1_HUMAN
NC score	0.018659 (rank : 131)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	170	Target Neighborhood Hits	354	Shared Neighborhood Hits	15
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

US6NL_MOUSE
NC score	0.017145 (rank : 132)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	170	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

ETV5_MOUSE
NC score	0.017070 (rank : 133)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	170	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

CUTL1_MOUSE
NC score	0.016356 (rank : 134)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	170	Target Neighborhood Hits	1620	Shared Neighborhood Hits	47
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TRI66_MOUSE
NC score	0.015885 (rank : 135)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	170	Target Neighborhood Hits	491	Shared Neighborhood Hits	39
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ATBF1_MOUSE
NC score	0.015735 (rank : 136)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	170	Target Neighborhood Hits	1841	Shared Neighborhood Hits	71
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TCF7_MOUSE
NC score	0.015298 (rank : 137)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	170	Target Neighborhood Hits	277	Shared Neighborhood Hits	24
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

BOLL_HUMAN
NC score	0.014921 (rank : 138)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	170	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N9W6, Q969U3	Gene names	BOLL, BOULE
Domain Architecture
Description	Protein boule-like.

BTBD7_MOUSE
NC score	0.014815 (rank : 139)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	170	Target Neighborhood Hits	228	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

ARHGF_HUMAN
NC score	0.014190 (rank : 140)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	170	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SC24D_HUMAN
NC score	0.013935 (rank : 141)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	170	Target Neighborhood Hits	173	Shared Neighborhood Hits	25
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

BCOR_HUMAN
NC score	0.013879 (rank : 142)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	170	Target Neighborhood Hits	609	Shared Neighborhood Hits	27
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CUTL1_HUMAN
NC score	0.013761 (rank : 143)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	170	Target Neighborhood Hits	1574	Shared Neighborhood Hits	34
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

PO2F2_HUMAN
NC score	0.013645 (rank : 144)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	170	Target Neighborhood Hits	379	Shared Neighborhood Hits	20
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RX_HUMAN
NC score	0.013510 (rank : 145)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	170	Target Neighborhood Hits	423	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

PCOC1_HUMAN
NC score	0.013490 (rank : 146)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	170	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

LSP1_HUMAN
NC score	0.012328 (rank : 147)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	170	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

AP1G1_MOUSE
NC score	0.011428 (rank : 148)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	170	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

DDEF1_MOUSE
NC score	0.011295 (rank : 149)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	170	Target Neighborhood Hits	592	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

FBX46_HUMAN
NC score	0.011112 (rank : 150)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	170	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PJ61	Gene names	FBXO46, FBX46, FBXO34L
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

PHLPP_HUMAN
NC score	0.010858 (rank : 151)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	170	Target Neighborhood Hits	604	Shared Neighborhood Hits	25
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

MYO15_MOUSE
NC score	0.010797 (rank : 152)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	170	Target Neighborhood Hits	467	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

AP1G1_HUMAN
NC score	0.010408 (rank : 153)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	170	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

STML1_HUMAN
NC score	0.009864 (rank : 154)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	170	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

FARP2_HUMAN
NC score	0.009797 (rank : 155)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	170	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

ZDHC8_HUMAN
NC score	0.009514 (rank : 156)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	170	Target Neighborhood Hits	234	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

FBN2_HUMAN
NC score	0.009388 (rank : 157)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	170	Target Neighborhood Hits	560	Shared Neighborhood Hits	6
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

GBF1_HUMAN
NC score	0.008740 (rank : 158)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	170	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

HME1_MOUSE
NC score	0.007653 (rank : 159)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	170	Target Neighborhood Hits	397	Shared Neighborhood Hits	17
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

SOX2_HUMAN
NC score	0.007622 (rank : 160)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	170	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

KBTB9_MOUSE
NC score	0.007581 (rank : 161)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	170	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

PP16A_MOUSE
NC score	0.007330 (rank : 162)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	170	Target Neighborhood Hits	318	Shared Neighborhood Hits	6
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

S13A2_HUMAN
NC score	0.007304 (rank : 163)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	170	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q13183	Gene names	SLC13A2, NADC1, SDCT1
Domain Architecture
Description	Solute carrier family 13 member 2 (Renal sodium/dicarboxylate cotransporter) (Na(+)/dicarboxylate cotransporter 1) (NaDC-1).

WEE1B_HUMAN
NC score	0.007050 (rank : 164)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	170	Target Neighborhood Hits	836	Shared Neighborhood Hits	19
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

WNK1_HUMAN
NC score	0.006896 (rank : 165)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	170	Target Neighborhood Hits	1158	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

CAC1B_HUMAN
NC score	0.006552 (rank : 166)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	170	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

VINEX_MOUSE
NC score	0.006540 (rank : 167)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	170	Target Neighborhood Hits	286	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

BNC1_MOUSE
NC score	0.006054 (rank : 168)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	170	Target Neighborhood Hits	582	Shared Neighborhood Hits	5
SwissProt Accessions	O35914, O54886	Gene names	Bnc1, Bnc
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

RBM19_MOUSE
NC score	0.005568 (rank : 169)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	170	Target Neighborhood Hits	296	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

INVS_HUMAN
NC score	0.005265 (rank : 170)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	170	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ROBO3_MOUSE
NC score	0.002840 (rank : 171)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	170	Target Neighborhood Hits	524	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

COR2A_MOUSE
NC score	0.002709 (rank : 172)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	170	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P5, Q3U6H8, Q8BW42	Gene names	Coro2a
Domain Architecture	No domain graphic available
Description	Coronin-2A.

CD45_HUMAN
NC score	0.001801 (rank : 173)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	170	Target Neighborhood Hits	243	Shared Neighborhood Hits	6
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

ZN438_HUMAN
NC score	0.001673 (rank : 174)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	170	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

TCF8_MOUSE
NC score	-0.000288 (rank : 175)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	170	Target Neighborhood Hits	1067	Shared Neighborhood Hits	22
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).