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Network neighborhood for query Sequence : HCN4_HUMAN

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HCN4_HUMAN
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HCN1_HUMAN
θ value	0 (rank : 1)	NC score	0.973135 (rank : 3)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN1_MOUSE
θ value	0 (rank : 2)	NC score	0.969226 (rank : 7)
Query Neighborhood Hits	303	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
θ value	0 (rank : 3)	NC score	0.966460 (rank : 8)
Query Neighborhood Hits	303	Target Neighborhood Hits	369	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	0 (rank : 4)	NC score	0.970497 (rank : 6)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	121
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN3_HUMAN
θ value	0 (rank : 5)	NC score	0.972279 (rank : 5)
Query Neighborhood Hits	303	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN3_MOUSE
θ value	0 (rank : 6)	NC score	0.972427 (rank : 4)
Query Neighborhood Hits	303	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN4_HUMAN
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	303	Target Neighborhood Hits	303	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
θ value	0 (rank : 8)	NC score	0.983167 (rank : 2)
Query Neighborhood Hits	303	Target Neighborhood Hits	284	Shared Neighborhood Hits	184
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CNGA1_MOUSE
θ value	3.48949e-44 (rank : 9)	NC score	0.836030 (rank : 12)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA2_MOUSE
θ value	7.77379e-44 (rank : 10)	NC score	0.847229 (rank : 9)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
θ value	2.26182e-43 (rank : 11)	NC score	0.841148 (rank : 10)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
θ value	5.03882e-43 (rank : 12)	NC score	0.836991 (rank : 11)
Query Neighborhood Hits	303	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

KCNH6_HUMAN
θ value	5.57106e-42 (rank : 13)	NC score	0.794141 (rank : 17)
Query Neighborhood Hits	303	Target Neighborhood Hits	222	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

CNGA3_HUMAN
θ value	9.50281e-42 (rank : 14)	NC score	0.834924 (rank : 13)
Query Neighborhood Hits	303	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

KCNH7_MOUSE
θ value	1.3722e-40 (rank : 15)	NC score	0.788468 (rank : 20)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH2_MOUSE
θ value	1.51715e-39 (rank : 16)	NC score	0.792674 (rank : 18)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
θ value	1.98146e-39 (rank : 17)	NC score	0.792173 (rank : 19)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	53
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_HUMAN
θ value	3.73686e-38 (rank : 18)	NC score	0.783640 (rank : 21)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH5_HUMAN
θ value	4.568e-36 (rank : 19)	NC score	0.777496 (rank : 24)
Query Neighborhood Hits	303	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	5.96599e-36 (rank : 20)	NC score	0.777599 (rank : 23)
Query Neighborhood Hits	303	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

CNGB1_HUMAN
θ value	1.9192e-34 (rank : 21)	NC score	0.815436 (rank : 15)
Query Neighborhood Hits	303	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH1_HUMAN
θ value	3.27365e-34 (rank : 22)	NC score	0.772109 (rank : 27)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	3.27365e-34 (rank : 23)	NC score	0.772422 (rank : 26)
Query Neighborhood Hits	303	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH8_HUMAN
θ value	3.61944e-33 (rank : 24)	NC score	0.773961 (rank : 25)
Query Neighborhood Hits	303	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
θ value	1.0531e-32 (rank : 25)	NC score	0.780310 (rank : 22)
Query Neighborhood Hits	303	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

CNGB3_MOUSE
θ value	3.06405e-32 (rank : 26)	NC score	0.819443 (rank : 14)
Query Neighborhood Hits	303	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB3_HUMAN
θ value	1.16434e-31 (rank : 27)	NC score	0.804977 (rank : 16)
Query Neighborhood Hits	303	Target Neighborhood Hits	206	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH3_MOUSE
θ value	8.3442e-30 (rank : 28)	NC score	0.764495 (rank : 29)
Query Neighborhood Hits	303	Target Neighborhood Hits	133	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH3_HUMAN
θ value	1.4233e-29 (rank : 29)	NC score	0.765714 (rank : 28)
Query Neighborhood Hits	303	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KAP0_HUMAN
θ value	1.29631e-06 (rank : 30)	NC score	0.318480 (rank : 30)
Query Neighborhood Hits	303	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
θ value	1.69304e-06 (rank : 31)	NC score	0.290288 (rank : 31)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KGP2_MOUSE
θ value	1.69304e-06 (rank : 32)	NC score	0.080113 (rank : 62)
Query Neighborhood Hits	303	Target Neighborhood Hits	1029	Shared Neighborhood Hits	54
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
θ value	2.21117e-06 (rank : 33)	NC score	0.080048 (rank : 63)
Query Neighborhood Hits	303	Target Neighborhood Hits	1023	Shared Neighborhood Hits	56
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

RGS3_MOUSE
θ value	3.77169e-06 (rank : 34)	NC score	0.089124 (rank : 51)
Query Neighborhood Hits	303	Target Neighborhood Hits	1621	Shared Neighborhood Hits	144
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

KAP2_MOUSE
θ value	1.43324e-05 (rank : 35)	NC score	0.265937 (rank : 34)
Query Neighborhood Hits	303	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
θ value	2.44474e-05 (rank : 36)	NC score	0.262039 (rank : 35)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

TCGAP_HUMAN
θ value	5.44631e-05 (rank : 37)	NC score	0.059169 (rank : 115)
Query Neighborhood Hits	303	Target Neighborhood Hits	872	Shared Neighborhood Hits	101
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

KGP1B_MOUSE
θ value	0.000158464 (rank : 38)	NC score	0.080994 (rank : 58)
Query Neighborhood Hits	303	Target Neighborhood Hits	922	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
θ value	0.000270298 (rank : 39)	NC score	0.080628 (rank : 60)
Query Neighborhood Hits	303	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.080970 (rank : 59)
Query Neighborhood Hits	303	Target Neighborhood Hits	921	Shared Neighborhood Hits	62
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

CAC1G_HUMAN
θ value	0.000461057 (rank : 41)	NC score	0.042849 (rank : 185)
Query Neighborhood Hits	303	Target Neighborhood Hits	587	Shared Neighborhood Hits	72
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

NACAM_MOUSE
θ value	0.000461057 (rank : 42)	NC score	0.102490 (rank : 40)
Query Neighborhood Hits	303	Target Neighborhood Hits	1866	Shared Neighborhood Hits	181
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HAIR_HUMAN
θ value	0.000786445 (rank : 43)	NC score	0.053050 (rank : 149)
Query Neighborhood Hits	303	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

MAGE1_HUMAN
θ value	0.000786445 (rank : 44)	NC score	0.073745 (rank : 69)
Query Neighborhood Hits	303	Target Neighborhood Hits	1389	Shared Neighborhood Hits	160
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

DOT1L_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.090252 (rank : 48)
Query Neighborhood Hits	303	Target Neighborhood Hits	660	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

KAP3_MOUSE
θ value	0.00102713 (rank : 46)	NC score	0.255086 (rank : 36)
Query Neighborhood Hits	303	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

EPN3_HUMAN
θ value	0.00134147 (rank : 47)	NC score	0.064193 (rank : 96)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

KAP3_HUMAN
θ value	0.00175202 (rank : 48)	NC score	0.249600 (rank : 37)
Query Neighborhood Hits	303	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

HRBL_MOUSE
θ value	0.00228821 (rank : 49)	NC score	0.052558 (rank : 150)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

RGS3_HUMAN
θ value	0.00665767 (rank : 50)	NC score	0.071051 (rank : 74)
Query Neighborhood Hits	303	Target Neighborhood Hits	1375	Shared Neighborhood Hits	110
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

KAP1_HUMAN
θ value	0.00869519 (rank : 51)	NC score	0.280795 (rank : 32)
Query Neighborhood Hits	303	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
θ value	0.00869519 (rank : 52)	NC score	0.277857 (rank : 33)
Query Neighborhood Hits	303	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

SRRM2_MOUSE
θ value	0.00869519 (rank : 53)	NC score	0.094546 (rank : 45)
Query Neighborhood Hits	303	Target Neighborhood Hits	1470	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TLE1_MOUSE
θ value	0.00869519 (rank : 54)	NC score	0.027833 (rank : 227)
Query Neighborhood Hits	303	Target Neighborhood Hits	491	Shared Neighborhood Hits	39
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ZN750_MOUSE
θ value	0.00869519 (rank : 55)	NC score	0.069312 (rank : 78)
Query Neighborhood Hits	303	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MLL3_HUMAN
θ value	0.0113563 (rank : 56)	NC score	0.068516 (rank : 81)
Query Neighborhood Hits	303	Target Neighborhood Hits	1644	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LR37A_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.046201 (rank : 175)
Query Neighborhood Hits	303	Target Neighborhood Hits	720	Shared Neighborhood Hits	65
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PUNC_MOUSE
θ value	0.0148317 (rank : 58)	NC score	0.013658 (rank : 294)
Query Neighborhood Hits	303	Target Neighborhood Hits	501	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

BCL9_HUMAN
θ value	0.0193708 (rank : 59)	NC score	0.095134 (rank : 44)
Query Neighborhood Hits	303	Target Neighborhood Hits	1008	Shared Neighborhood Hits	124
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DIDO1_HUMAN
θ value	0.0193708 (rank : 60)	NC score	0.061212 (rank : 108)
Query Neighborhood Hits	303	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EPN3_MOUSE
θ value	0.0252991 (rank : 61)	NC score	0.055677 (rank : 133)
Query Neighborhood Hits	303	Target Neighborhood Hits	312	Shared Neighborhood Hits	56
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

IASPP_MOUSE
θ value	0.0252991 (rank : 62)	NC score	0.044273 (rank : 177)
Query Neighborhood Hits	303	Target Neighborhood Hits	1024	Shared Neighborhood Hits	101
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PRRT3_HUMAN
θ value	0.0252991 (rank : 63)	NC score	0.093719 (rank : 46)
Query Neighborhood Hits	303	Target Neighborhood Hits	998	Shared Neighborhood Hits	119
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MDC1_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.057648 (rank : 123)
Query Neighborhood Hits	303	Target Neighborhood Hits	1446	Shared Neighborhood Hits	115
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PCLO_MOUSE
θ value	0.0330416 (rank : 65)	NC score	0.068072 (rank : 82)
Query Neighborhood Hits	303	Target Neighborhood Hits	2275	Shared Neighborhood Hits	187
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ZN687_HUMAN
θ value	0.0330416 (rank : 66)	NC score	0.020112 (rank : 260)
Query Neighborhood Hits	303	Target Neighborhood Hits	1244	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MISS_MOUSE
θ value	0.0431538 (rank : 67)	NC score	0.072088 (rank : 73)
Query Neighborhood Hits	303	Target Neighborhood Hits	444	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

ZN516_MOUSE
θ value	0.0431538 (rank : 68)	NC score	0.016132 (rank : 278)
Query Neighborhood Hits	303	Target Neighborhood Hits	1197	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

EP300_HUMAN
θ value	0.0563607 (rank : 69)	NC score	0.066751 (rank : 85)
Query Neighborhood Hits	303	Target Neighborhood Hits	821	Shared Neighborhood Hits	130
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GNAS1_HUMAN
θ value	0.0563607 (rank : 70)	NC score	0.029225 (rank : 219)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TLE1_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.027852 (rank : 226)
Query Neighborhood Hits	303	Target Neighborhood Hits	485	Shared Neighborhood Hits	40
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

PGCA_MOUSE
θ value	0.0736092 (rank : 72)	NC score	0.022933 (rank : 248)
Query Neighborhood Hits	303	Target Neighborhood Hits	643	Shared Neighborhood Hits	49
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

RUNX3_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.033229 (rank : 208)
Query Neighborhood Hits	303	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

ZIM10_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.048890 (rank : 167)
Query Neighborhood Hits	303	Target Neighborhood Hits	577	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN409_HUMAN
θ value	0.0736092 (rank : 75)	NC score	0.024285 (rank : 244)
Query Neighborhood Hits	303	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

BSN_MOUSE
θ value	0.0961366 (rank : 76)	NC score	0.089784 (rank : 49)
Query Neighborhood Hits	303	Target Neighborhood Hits	2057	Shared Neighborhood Hits	186
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MEGF9_MOUSE
θ value	0.0961366 (rank : 77)	NC score	0.031269 (rank : 214)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NCOR2_MOUSE
θ value	0.0961366 (rank : 78)	NC score	0.057056 (rank : 126)
Query Neighborhood Hits	303	Target Neighborhood Hits	790	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PDZD2_HUMAN
θ value	0.0961366 (rank : 79)	NC score	0.053919 (rank : 147)
Query Neighborhood Hits	303	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SC24C_HUMAN
θ value	0.125558 (rank : 80)	NC score	0.072273 (rank : 71)
Query Neighborhood Hits	303	Target Neighborhood Hits	662	Shared Neighborhood Hits	99
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MUCDL_HUMAN
θ value	0.163984 (rank : 81)	NC score	0.066203 (rank : 89)
Query Neighborhood Hits	303	Target Neighborhood Hits	777	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFH_MOUSE
θ value	0.163984 (rank : 82)	NC score	0.050190 (rank : 164)
Query Neighborhood Hits	303	Target Neighborhood Hits	2247	Shared Neighborhood Hits	150
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RUNX3_HUMAN
θ value	0.163984 (rank : 83)	NC score	0.032403 (rank : 212)
Query Neighborhood Hits	303	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

SAPS1_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.069754 (rank : 77)
Query Neighborhood Hits	303	Target Neighborhood Hits	704	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CIC_MOUSE
θ value	0.21417 (rank : 85)	NC score	0.054741 (rank : 140)
Query Neighborhood Hits	303	Target Neighborhood Hits	742	Shared Neighborhood Hits	134
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO5A2_HUMAN
θ value	0.21417 (rank : 86)	NC score	0.034936 (rank : 203)
Query Neighborhood Hits	303	Target Neighborhood Hits	760	Shared Neighborhood Hits	101
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

FHOD1_MOUSE
θ value	0.21417 (rank : 87)	NC score	0.028473 (rank : 224)
Query Neighborhood Hits	303	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

NCOA2_HUMAN
θ value	0.21417 (rank : 88)	NC score	0.038857 (rank : 191)
Query Neighborhood Hits	303	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

TPO_MOUSE
θ value	0.21417 (rank : 89)	NC score	0.051798 (rank : 153)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

CT152_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.161990 (rank : 38)
Query Neighborhood Hits	303	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

EHMT2_MOUSE
θ value	0.279714 (rank : 91)	NC score	0.025534 (rank : 238)
Query Neighborhood Hits	303	Target Neighborhood Hits	750	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FOXN4_MOUSE
θ value	0.279714 (rank : 92)	NC score	0.012160 (rank : 304)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

NCOA6_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.089523 (rank : 50)
Query Neighborhood Hits	303	Target Neighborhood Hits	1202	Shared Neighborhood Hits	140
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OGFR_HUMAN
θ value	0.279714 (rank : 94)	NC score	0.082232 (rank : 56)
Query Neighborhood Hits	303	Target Neighborhood Hits	1582	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

S23IP_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.048976 (rank : 166)
Query Neighborhood Hits	303	Target Neighborhood Hits	363	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ZN385_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.052118 (rank : 151)
Query Neighborhood Hits	303	Target Neighborhood Hits	614	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ELOA2_HUMAN
θ value	0.365318 (rank : 97)	NC score	0.024844 (rank : 241)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

KCNS3_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.014412 (rank : 288)
Query Neighborhood Hits	303	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

MDC1_MOUSE
θ value	0.365318 (rank : 99)	NC score	0.070187 (rank : 75)
Query Neighborhood Hits	303	Target Neighborhood Hits	998	Shared Neighborhood Hits	106
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PER3_HUMAN
θ value	0.365318 (rank : 100)	NC score	0.038637 (rank : 192)
Query Neighborhood Hits	303	Target Neighborhood Hits	479	Shared Neighborhood Hits	72
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

SON_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.060822 (rank : 109)
Query Neighborhood Hits	303	Target Neighborhood Hits	1568	Shared Neighborhood Hits	137
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ULK1_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.013462 (rank : 296)
Query Neighborhood Hits	303	Target Neighborhood Hits	1121	Shared Neighborhood Hits	69
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZCH11_HUMAN
θ value	0.365318 (rank : 103)	NC score	0.027568 (rank : 230)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

BCL9_MOUSE
θ value	0.47712 (rank : 104)	NC score	0.085363 (rank : 52)
Query Neighborhood Hits	303	Target Neighborhood Hits	770	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CBP_HUMAN
θ value	0.47712 (rank : 105)	NC score	0.072213 (rank : 72)
Query Neighborhood Hits	303	Target Neighborhood Hits	941	Shared Neighborhood Hits	141
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CO9A1_HUMAN
θ value	0.47712 (rank : 106)	NC score	0.020112 (rank : 259)
Query Neighborhood Hits	303	Target Neighborhood Hits	420	Shared Neighborhood Hits	58
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

REC8L_MOUSE
θ value	0.47712 (rank : 107)	NC score	0.025150 (rank : 240)
Query Neighborhood Hits	303	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5S7, Q3UIN9, Q9JK52	Gene names	Rec8L1, Rec8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

S5A2_HUMAN
θ value	0.47712 (rank : 108)	NC score	0.029129 (rank : 221)
Query Neighborhood Hits	303	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P31213, Q9BYE6	Gene names	SRD5A2
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5- alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II 5-alpha reductase).

SC6A5_MOUSE
θ value	0.47712 (rank : 109)	NC score	0.015153 (rank : 284)
Query Neighborhood Hits	303	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

TLE3_MOUSE
θ value	0.47712 (rank : 110)	NC score	0.020976 (rank : 255)
Query Neighborhood Hits	303	Target Neighborhood Hits	378	Shared Neighborhood Hits	22
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

BCOR_MOUSE
θ value	0.62314 (rank : 111)	NC score	0.017774 (rank : 275)
Query Neighborhood Hits	303	Target Neighborhood Hits	521	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CBP_MOUSE
θ value	0.62314 (rank : 112)	NC score	0.066538 (rank : 87)
Query Neighborhood Hits	303	Target Neighborhood Hits	1051	Shared Neighborhood Hits	133
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCR3_MOUSE
θ value	0.62314 (rank : 113)	NC score	0.012658 (rank : 300)
Query Neighborhood Hits	303	Target Neighborhood Hits	781	Shared Neighborhood Hits	11
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

CEP68_HUMAN
θ value	0.62314 (rank : 114)	NC score	0.045691 (rank : 176)
Query Neighborhood Hits	303	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CTND2_MOUSE
θ value	0.62314 (rank : 115)	NC score	0.020770 (rank : 256)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

K1683_HUMAN
θ value	0.62314 (rank : 116)	NC score	0.039863 (rank : 190)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

NUMBL_HUMAN
θ value	0.62314 (rank : 117)	NC score	0.026087 (rank : 236)
Query Neighborhood Hits	303	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

RP3A_MOUSE
θ value	0.62314 (rank : 118)	NC score	0.027266 (rank : 232)
Query Neighborhood Hits	303	Target Neighborhood Hits	510	Shared Neighborhood Hits	74
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SN1L1_HUMAN
θ value	0.62314 (rank : 119)	NC score	0.008897 (rank : 328)
Query Neighborhood Hits	303	Target Neighborhood Hits	911	Shared Neighborhood Hits	27
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

SPT5H_MOUSE
θ value	0.62314 (rank : 120)	NC score	0.050489 (rank : 160)
Query Neighborhood Hits	303	Target Neighborhood Hits	437	Shared Neighborhood Hits	65
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

ARID2_HUMAN
θ value	0.813845 (rank : 121)	NC score	0.033482 (rank : 207)
Query Neighborhood Hits	303	Target Neighborhood Hits	302	Shared Neighborhood Hits	40
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

FOG1_MOUSE
θ value	0.813845 (rank : 122)	NC score	0.015557 (rank : 280)
Query Neighborhood Hits	303	Target Neighborhood Hits	1237	Shared Neighborhood Hits	99
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SPT5H_HUMAN
θ value	0.813845 (rank : 123)	NC score	0.049937 (rank : 165)
Query Neighborhood Hits	303	Target Neighborhood Hits	436	Shared Neighborhood Hits	65
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

STK10_MOUSE
θ value	0.813845 (rank : 124)	NC score	0.007974 (rank : 332)
Query Neighborhood Hits	303	Target Neighborhood Hits	2132	Shared Neighborhood Hits	61
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

AFF2_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.027570 (rank : 229)
Query Neighborhood Hits	303	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

BIN1_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.030029 (rank : 218)
Query Neighborhood Hits	303	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CAC1B_MOUSE
θ value	1.06291 (rank : 127)	NC score	0.018816 (rank : 267)
Query Neighborhood Hits	303	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CBL_MOUSE
θ value	1.06291 (rank : 128)	NC score	0.034543 (rank : 205)
Query Neighborhood Hits	303	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CO9A1_MOUSE
θ value	1.06291 (rank : 129)	NC score	0.021875 (rank : 251)
Query Neighborhood Hits	303	Target Neighborhood Hits	477	Shared Neighborhood Hits	69
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

DMRTD_HUMAN
θ value	1.06291 (rank : 130)	NC score	0.030578 (rank : 217)
Query Neighborhood Hits	303	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

K0323_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.018007 (rank : 274)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

K1802_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.037637 (rank : 196)
Query Neighborhood Hits	303	Target Neighborhood Hits	1596	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

SEM6C_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.019460 (rank : 264)
Query Neighborhood Hits	303	Target Neighborhood Hits	352	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ZIM10_MOUSE
θ value	1.06291 (rank : 134)	NC score	0.037675 (rank : 195)
Query Neighborhood Hits	303	Target Neighborhood Hits	430	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ARNT_MOUSE
θ value	1.38821 (rank : 135)	NC score	0.015802 (rank : 279)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BCOR_HUMAN
θ value	1.38821 (rank : 136)	NC score	0.027016 (rank : 233)
Query Neighborhood Hits	303	Target Neighborhood Hits	609	Shared Neighborhood Hits	44
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CBL_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.029189 (rank : 220)
Query Neighborhood Hits	303	Target Neighborhood Hits	353	Shared Neighborhood Hits	29
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CSF1_HUMAN
θ value	1.38821 (rank : 138)	NC score	0.037149 (rank : 199)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

GLI2_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.003487 (rank : 357)
Query Neighborhood Hits	303	Target Neighborhood Hits	971	Shared Neighborhood Hits	57
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

HXB3_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.006996 (rank : 339)
Query Neighborhood Hits	303	Target Neighborhood Hits	559	Shared Neighborhood Hits	37
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

JIP3_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.014214 (rank : 291)
Query Neighborhood Hits	303	Target Neighborhood Hits	1039	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

MARK2_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.012512 (rank : 301)
Query Neighborhood Hits	303	Target Neighborhood Hits	1056	Shared Neighborhood Hits	52
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

PCOC1_HUMAN
θ value	1.38821 (rank : 143)	NC score	0.006622 (rank : 342)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

SSBP4_HUMAN
θ value	1.38821 (rank : 144)	NC score	0.058843 (rank : 118)
Query Neighborhood Hits	303	Target Neighborhood Hits	753	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TRIM8_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.010952 (rank : 310)
Query Neighborhood Hits	303	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BAT3_MOUSE
θ value	1.81305 (rank : 146)	NC score	0.067307 (rank : 84)
Query Neighborhood Hits	303	Target Neighborhood Hits	518	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAZ2A_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.026231 (rank : 234)
Query Neighborhood Hits	303	Target Neighborhood Hits	744	Shared Neighborhood Hits	73
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CI079_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.043841 (rank : 179)
Query Neighborhood Hits	303	Target Neighborhood Hits	288	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CIC_HUMAN
θ value	1.81305 (rank : 149)	NC score	0.072989 (rank : 70)
Query Neighborhood Hits	303	Target Neighborhood Hits	992	Shared Neighborhood Hits	146
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CSKI1_MOUSE
θ value	1.81305 (rank : 150)	NC score	0.033018 (rank : 209)
Query Neighborhood Hits	303	Target Neighborhood Hits	1031	Shared Neighborhood Hits	125
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DEN1A_HUMAN
θ value	1.81305 (rank : 151)	NC score	0.024332 (rank : 243)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ERBB2_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.006989 (rank : 340)
Query Neighborhood Hits	303	Target Neighborhood Hits	1073	Shared Neighborhood Hits	44
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FA8A1_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.061862 (rank : 105)
Query Neighborhood Hits	303	Target Neighborhood Hits	53	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

FRS3_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.014267 (rank : 289)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

JIP1_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.028907 (rank : 222)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

K0999_MOUSE
θ value	1.81305 (rank : 156)	NC score	0.009638 (rank : 318)
Query Neighborhood Hits	303	Target Neighborhood Hits	931	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

LSD1_HUMAN
θ value	1.81305 (rank : 157)	NC score	0.027650 (rank : 228)
Query Neighborhood Hits	303	Target Neighborhood Hits	455	Shared Neighborhood Hits	38
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MINT_MOUSE
θ value	1.81305 (rank : 158)	NC score	0.046352 (rank : 173)
Query Neighborhood Hits	303	Target Neighborhood Hits	1514	Shared Neighborhood Hits	115
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NRX2A_HUMAN
θ value	1.81305 (rank : 159)	NC score	0.028204 (rank : 225)
Query Neighborhood Hits	303	Target Neighborhood Hits	614	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 160)	NC score	0.043507 (rank : 181)
Query Neighborhood Hits	303	Target Neighborhood Hits	481	Shared Neighborhood Hits	63
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PI5PA_HUMAN
θ value	1.81305 (rank : 161)	NC score	0.063913 (rank : 97)
Query Neighborhood Hits	303	Target Neighborhood Hits	749	Shared Neighborhood Hits	116
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

R3HD2_MOUSE
θ value	1.81305 (rank : 162)	NC score	0.065284 (rank : 92)
Query Neighborhood Hits	303	Target Neighborhood Hits	397	Shared Neighborhood Hits	64
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RNF25_HUMAN
θ value	1.81305 (rank : 163)	NC score	0.025398 (rank : 239)
Query Neighborhood Hits	303	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

T22D4_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.047423 (rank : 170)
Query Neighborhood Hits	303	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARA_HUMAN
θ value	1.81305 (rank : 165)	NC score	0.048117 (rank : 169)
Query Neighborhood Hits	303	Target Neighborhood Hits	1626	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ULK1_MOUSE
θ value	1.81305 (rank : 166)	NC score	0.013096 (rank : 298)
Query Neighborhood Hits	303	Target Neighborhood Hits	1214	Shared Neighborhood Hits	73
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZDH14_HUMAN
θ value	1.81305 (rank : 167)	NC score	0.012139 (rank : 305)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

B3A3_HUMAN
θ value	2.36792 (rank : 168)	NC score	0.009960 (rank : 315)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

B4GT1_HUMAN
θ value	2.36792 (rank : 169)	NC score	0.019541 (rank : 263)
Query Neighborhood Hits	303	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CAC1H_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.028504 (rank : 223)
Query Neighborhood Hits	303	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CO4A2_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.017000 (rank : 277)
Query Neighborhood Hits	303	Target Neighborhood Hits	454	Shared Neighborhood Hits	66
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COIA1_HUMAN
θ value	2.36792 (rank : 172)	NC score	0.035856 (rank : 201)
Query Neighborhood Hits	303	Target Neighborhood Hits	447	Shared Neighborhood Hits	89
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CRSP2_HUMAN
θ value	2.36792 (rank : 173)	NC score	0.055559 (rank : 134)
Query Neighborhood Hits	303	Target Neighborhood Hits	380	Shared Neighborhood Hits	66
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CTND2_HUMAN
θ value	2.36792 (rank : 174)	NC score	0.023749 (rank : 245)
Query Neighborhood Hits	303	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

DCC_MOUSE
θ value	2.36792 (rank : 175)	NC score	0.014987 (rank : 285)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	49
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DTNB_MOUSE
θ value	2.36792 (rank : 176)	NC score	0.007827 (rank : 334)
Query Neighborhood Hits	303	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

F100B_MOUSE
θ value	2.36792 (rank : 177)	NC score	0.021027 (rank : 254)
Query Neighborhood Hits	303	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

FILA_HUMAN
θ value	2.36792 (rank : 178)	NC score	0.013863 (rank : 292)
Query Neighborhood Hits	303	Target Neighborhood Hits	685	Shared Neighborhood Hits	33
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GMEB2_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.018627 (rank : 270)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

HTRA4_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.032995 (rank : 210)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IF4G1_MOUSE
θ value	2.36792 (rank : 181)	NC score	0.038624 (rank : 193)
Query Neighborhood Hits	303	Target Neighborhood Hits	534	Shared Neighborhood Hits	82
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

INVS_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.017695 (rank : 276)
Query Neighborhood Hits	303	Target Neighborhood Hits	609	Shared Neighborhood Hits	58
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LPP_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.030758 (rank : 216)
Query Neighborhood Hits	303	Target Neighborhood Hits	775	Shared Neighborhood Hits	87
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MSX3_MOUSE
θ value	2.36792 (rank : 184)	NC score	0.001259 (rank : 361)
Query Neighborhood Hits	303	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

MTSS1_HUMAN
θ value	2.36792 (rank : 185)	NC score	0.025953 (rank : 237)
Query Neighborhood Hits	303	Target Neighborhood Hits	504	Shared Neighborhood Hits	56
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NU133_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.023358 (rank : 246)
Query Neighborhood Hits	303	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PHLPP_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.026189 (rank : 235)
Query Neighborhood Hits	303	Target Neighborhood Hits	604	Shared Neighborhood Hits	69
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PKN3_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.011512 (rank : 307)
Query Neighborhood Hits	303	Target Neighborhood Hits	1009	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PRGR_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.007352 (rank : 336)
Query Neighborhood Hits	303	Target Neighborhood Hits	286	Shared Neighborhood Hits	34
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

RORG_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.002638 (rank : 359)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

SC24A_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.043398 (rank : 182)
Query Neighborhood Hits	303	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SORC3_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.007462 (rank : 335)
Query Neighborhood Hits	303	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

TFE2_HUMAN
θ value	2.36792 (rank : 193)	NC score	0.013399 (rank : 297)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TGON2_HUMAN
θ value	2.36792 (rank : 194)	NC score	0.046368 (rank : 172)
Query Neighborhood Hits	303	Target Neighborhood Hits	1037	Shared Neighborhood Hits	88
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

THAP7_MOUSE
θ value	2.36792 (rank : 195)	NC score	0.018250 (rank : 272)
Query Neighborhood Hits	303	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

TSC1_HUMAN
θ value	2.36792 (rank : 196)	NC score	0.008643 (rank : 331)
Query Neighborhood Hits	303	Target Neighborhood Hits	765	Shared Neighborhood Hits	32
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TSH1_MOUSE
θ value	2.36792 (rank : 197)	NC score	0.013687 (rank : 293)
Query Neighborhood Hits	303	Target Neighborhood Hits	675	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ARHG1_MOUSE
θ value	3.0926 (rank : 198)	NC score	0.013518 (rank : 295)
Query Neighborhood Hits	303	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

CRTC1_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.051033 (rank : 158)
Query Neighborhood Hits	303	Target Neighborhood Hits	319	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CT152_HUMAN
θ value	3.0926 (rank : 200)	NC score	0.095929 (rank : 42)
Query Neighborhood Hits	303	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

DCNP1_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.041250 (rank : 188)
Query Neighborhood Hits	303	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF63	Gene names	DCNP1, C5orf20
Domain Architecture	No domain graphic available
Description	Dendritic cell nuclear protein 1.

GAK_HUMAN
θ value	3.0926 (rank : 202)	NC score	0.009243 (rank : 325)
Query Neighborhood Hits	303	Target Neighborhood Hits	1028	Shared Neighborhood Hits	57
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

K0056_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.022661 (rank : 249)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

MEF2D_HUMAN
θ value	3.0926 (rank : 204)	NC score	0.037208 (rank : 198)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MLL3_MOUSE
θ value	3.0926 (rank : 205)	NC score	0.054536 (rank : 142)
Query Neighborhood Hits	303	Target Neighborhood Hits	1399	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYO15_MOUSE
θ value	3.0926 (rank : 206)	NC score	0.009473 (rank : 321)
Query Neighborhood Hits	303	Target Neighborhood Hits	467	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NALP1_HUMAN
θ value	3.0926 (rank : 207)	NC score	0.006133 (rank : 347)
Query Neighborhood Hits	303	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NFAC1_MOUSE
θ value	3.0926 (rank : 208)	NC score	0.008983 (rank : 327)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	14
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PP14A_MOUSE
θ value	3.0926 (rank : 209)	NC score	0.037233 (rank : 197)
Query Neighborhood Hits	303	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

RNF25_MOUSE
θ value	3.0926 (rank : 210)	NC score	0.020149 (rank : 258)
Query Neighborhood Hits	303	Target Neighborhood Hits	106	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

RP1L1_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.032697 (rank : 211)
Query Neighborhood Hits	303	Target Neighborhood Hits	1072	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SEM6B_HUMAN
θ value	3.0926 (rank : 212)	NC score	0.009398 (rank : 323)
Query Neighborhood Hits	303	Target Neighborhood Hits	187	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

THAP7_HUMAN
θ value	3.0926 (rank : 213)	NC score	0.018345 (rank : 271)
Query Neighborhood Hits	303	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

TRIM8_MOUSE
θ value	3.0926 (rank : 214)	NC score	0.009288 (rank : 324)
Query Neighborhood Hits	303	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

WWP2_HUMAN
θ value	3.0926 (rank : 215)	NC score	0.005199 (rank : 351)
Query Neighborhood Hits	303	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ZDHC8_HUMAN
θ value	3.0926 (rank : 216)	NC score	0.015469 (rank : 282)
Query Neighborhood Hits	303	Target Neighborhood Hits	234	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZIMP7_MOUSE
θ value	3.0926 (rank : 217)	NC score	0.051120 (rank : 157)
Query Neighborhood Hits	303	Target Neighborhood Hits	566	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN598_HUMAN
θ value	3.0926 (rank : 218)	NC score	0.036950 (rank : 200)
Query Neighborhood Hits	303	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ABL1_HUMAN
θ value	4.03905 (rank : 219)	NC score	0.005693 (rank : 350)
Query Neighborhood Hits	303	Target Neighborhood Hits	1220	Shared Neighborhood Hits	66
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ALEX_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.063741 (rank : 99)
Query Neighborhood Hits	303	Target Neighborhood Hits	361	Shared Neighborhood Hits	81
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CAC1H_MOUSE
θ value	4.03905 (rank : 221)	NC score	0.021713 (rank : 252)
Query Neighborhood Hits	303	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAMKV_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.012848 (rank : 299)
Query Neighborhood Hits	303	Target Neighborhood Hits	1084	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CD248_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.018773 (rank : 269)
Query Neighborhood Hits	303	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSKI1_HUMAN
θ value	4.03905 (rank : 224)	NC score	0.033920 (rank : 206)
Query Neighborhood Hits	303	Target Neighborhood Hits	997	Shared Neighborhood Hits	130
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HXD3_HUMAN
θ value	4.03905 (rank : 225)	NC score	0.004780 (rank : 353)
Query Neighborhood Hits	303	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

JPH2_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.046338 (rank : 174)
Query Neighborhood Hits	303	Target Neighborhood Hits	639	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1543_MOUSE
θ value	4.03905 (rank : 227)	NC score	0.031483 (rank : 213)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	69
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAVS_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.042866 (rank : 183)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MEF2D_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.035343 (rank : 202)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MKL1_MOUSE
θ value	4.03905 (rank : 230)	NC score	0.043829 (rank : 180)
Query Neighborhood Hits	303	Target Neighborhood Hits	667	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NCOA1_HUMAN
θ value	4.03905 (rank : 231)	NC score	0.014707 (rank : 286)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

RB_HUMAN
θ value	4.03905 (rank : 232)	NC score	0.012415 (rank : 302)
Query Neighborhood Hits	303	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P06400, P78499, Q5VW46, Q8IZL4	Gene names	RB1
Domain Architecture
Description	Retinoblastoma-associated protein (PP110) (P105-RB) (RB).

S45A3_MOUSE
θ value	4.03905 (rank : 233)	NC score	0.008745 (rank : 330)
Query Neighborhood Hits	303	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0H7, Q8K252, Q8R1I0	Gene names	Slc45a3, Pcanap6, Prst
Domain Architecture	No domain graphic available
Description	Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein).

SETX_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.011218 (rank : 308)
Query Neighborhood Hits	303	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SPAG1_MOUSE
θ value	4.03905 (rank : 235)	NC score	0.009467 (rank : 322)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SYNJ1_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.042852 (rank : 184)
Query Neighborhood Hits	303	Target Neighborhood Hits	498	Shared Neighborhood Hits	110
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAAR1_HUMAN
θ value	4.03905 (rank : 237)	NC score	0.000035 (rank : 365)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

TAU_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.044184 (rank : 178)
Query Neighborhood Hits	303	Target Neighborhood Hits	448	Shared Neighborhood Hits	84
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TSH1_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.008826 (rank : 329)
Query Neighborhood Hits	303	Target Neighborhood Hits	558	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

UBQL3_MOUSE
θ value	4.03905 (rank : 240)	NC score	0.009668 (rank : 317)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

ZN236_HUMAN
θ value	4.03905 (rank : 241)	NC score	-0.003213 (rank : 368)
Query Neighborhood Hits	303	Target Neighborhood Hits	844	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ARI1A_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.047334 (rank : 171)
Query Neighborhood Hits	303	Target Neighborhood Hits	787	Shared Neighborhood Hits	118
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BAT3_HUMAN
θ value	5.27518 (rank : 243)	NC score	0.054824 (rank : 139)
Query Neighborhood Hits	303	Target Neighborhood Hits	490	Shared Neighborhood Hits	83
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CECR2_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.038271 (rank : 194)
Query Neighborhood Hits	303	Target Neighborhood Hits	543	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CO7A1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.023297 (rank : 247)
Query Neighborhood Hits	303	Target Neighborhood Hits	807	Shared Neighborhood Hits	99
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DC1L2_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.010484 (rank : 314)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

FOXJ2_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.009729 (rank : 316)
Query Neighborhood Hits	303	Target Neighborhood Hits	239	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

GAB2_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.011780 (rank : 306)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

HXD1_MOUSE
θ value	5.27518 (rank : 249)	NC score	0.000894 (rank : 363)
Query Neighborhood Hits	303	Target Neighborhood Hits	381	Shared Neighborhood Hits	12
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

KCNK1_MOUSE
θ value	5.27518 (rank : 250)	NC score	0.041358 (rank : 186)
Query Neighborhood Hits	303	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

LPIN3_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.007906 (rank : 333)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MAGD4_HUMAN
θ value	5.27518 (rank : 252)	NC score	0.031095 (rank : 215)
Query Neighborhood Hits	303	Target Neighborhood Hits	338	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MEFV_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.003589 (rank : 356)
Query Neighborhood Hits	303	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MK15_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.006559 (rank : 344)
Query Neighborhood Hits	303	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

NFRKB_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.027309 (rank : 231)
Query Neighborhood Hits	303	Target Neighborhood Hits	211	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NOTC2_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.003261 (rank : 358)
Query Neighborhood Hits	303	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NSD1_MOUSE
θ value	5.27518 (rank : 257)	NC score	0.019374 (rank : 265)
Query Neighborhood Hits	303	Target Neighborhood Hits	472	Shared Neighborhood Hits	47
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PAPPA_HUMAN
θ value	5.27518 (rank : 258)	NC score	0.006587 (rank : 343)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PKHA5_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.012277 (rank : 303)
Query Neighborhood Hits	303	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RLF_HUMAN
θ value	5.27518 (rank : 260)	NC score	0.000515 (rank : 364)
Query Neighborhood Hits	303	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

SPEG_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.018841 (rank : 266)
Query Neighborhood Hits	303	Target Neighborhood Hits	1959	Shared Neighborhood Hits	132
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRC_MOUSE
θ value	5.27518 (rank : 262)	NC score	0.001910 (rank : 360)
Query Neighborhood Hits	303	Target Neighborhood Hits	1033	Shared Neighborhood Hits	26
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

TTLL5_MOUSE
θ value	5.27518 (rank : 263)	NC score	0.007133 (rank : 338)
Query Neighborhood Hits	303	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

ACD_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.019601 (rank : 262)
Query Neighborhood Hits	303	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ADA12_MOUSE
θ value	6.88961 (rank : 265)	NC score	0.004823 (rank : 352)
Query Neighborhood Hits	303	Target Neighborhood Hits	474	Shared Neighborhood Hits	41
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

GLIS3_MOUSE
θ value	6.88961 (rank : 266)	NC score	-0.000805 (rank : 367)
Query Neighborhood Hits	303	Target Neighborhood Hits	861	Shared Neighborhood Hits	43
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

HSF4_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.009022 (rank : 326)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

HUNK_MOUSE
θ value	6.88961 (rank : 268)	NC score	0.007176 (rank : 337)
Query Neighborhood Hits	303	Target Neighborhood Hits	874	Shared Neighborhood Hits	25
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

IQEC3_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.022343 (rank : 250)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MILK1_MOUSE
θ value	6.88961 (rank : 270)	NC score	0.048869 (rank : 168)
Query Neighborhood Hits	303	Target Neighborhood Hits	788	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NCOR2_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.054259 (rank : 145)
Query Neighborhood Hits	303	Target Neighborhood Hits	870	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RECQ5_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.010556 (rank : 312)
Query Neighborhood Hits	303	Target Neighborhood Hits	390	Shared Neighborhood Hits	39
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RUSC2_HUMAN
θ value	6.88961 (rank : 273)	NC score	0.021616 (rank : 253)
Query Neighborhood Hits	303	Target Neighborhood Hits	205	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

TLE3_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.018779 (rank : 268)
Query Neighborhood Hits	303	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

ZHX3_HUMAN
θ value	6.88961 (rank : 275)	NC score	0.005947 (rank : 349)
Query Neighborhood Hits	303	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

AATK_HUMAN
θ value	8.99809 (rank : 276)	NC score	0.011104 (rank : 309)
Query Neighborhood Hits	303	Target Neighborhood Hits	1243	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

BAT2_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.061863 (rank : 104)
Query Neighborhood Hits	303	Target Neighborhood Hits	947	Shared Neighborhood Hits	140
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCAR1_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.018233 (rank : 273)
Query Neighborhood Hits	303	Target Neighborhood Hits	554	Shared Neighborhood Hits	58
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

BCL7C_MOUSE
θ value	8.99809 (rank : 279)	NC score	0.015252 (rank : 283)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CJ108_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.019609 (rank : 261)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CO4A1_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.024427 (rank : 242)
Query Neighborhood Hits	303	Target Neighborhood Hits	450	Shared Neighborhood Hits	85
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

FGD5_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.003637 (rank : 355)
Query Neighborhood Hits	303	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

GAB1_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.009496 (rank : 320)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

IF4B_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.014415 (rank : 287)
Query Neighborhood Hits	303	Target Neighborhood Hits	417	Shared Neighborhood Hits	35
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KCNK1_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.040450 (rank : 189)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

M3K3_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.006176 (rank : 346)
Query Neighborhood Hits	303	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MLL2_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.063343 (rank : 100)
Query Neighborhood Hits	303	Target Neighborhood Hits	1788	Shared Neighborhood Hits	173
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MORN1_HUMAN
θ value	8.99809 (rank : 288)	NC score	0.009555 (rank : 319)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

MPIP2_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.004098 (rank : 354)
Query Neighborhood Hits	303	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P30306, Q99LP3	Gene names	Cdc25b, Cdc25m2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

MTR1L_HUMAN
θ value	8.99809 (rank : 290)	NC score	-0.000734 (rank : 366)
Query Neighborhood Hits	303	Target Neighborhood Hits	1180	Shared Neighborhood Hits	38
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

MUC1_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.069269 (rank : 79)
Query Neighborhood Hits	303	Target Neighborhood Hits	975	Shared Neighborhood Hits	117
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PKHA6_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.014242 (rank : 290)
Query Neighborhood Hits	303	Target Neighborhood Hits	556	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PUM2_MOUSE
θ value	8.99809 (rank : 293)	NC score	0.006069 (rank : 348)
Query Neighborhood Hits	303	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

PYGO1_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.010487 (rank : 313)
Query Neighborhood Hits	303	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

PYR1_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.015491 (rank : 281)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

RUSC2_MOUSE
θ value	8.99809 (rank : 296)	NC score	0.034796 (rank : 204)
Query Neighborhood Hits	303	Target Neighborhood Hits	305	Shared Neighborhood Hits	58
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SALL2_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.000969 (rank : 362)
Query Neighborhood Hits	303	Target Neighborhood Hits	835	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

SON_MOUSE
θ value	8.99809 (rank : 298)	NC score	0.041251 (rank : 187)
Query Neighborhood Hits	303	Target Neighborhood Hits	957	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TACC2_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.010654 (rank : 311)
Query Neighborhood Hits	303	Target Neighborhood Hits	856	Shared Neighborhood Hits	51
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TCRG1_MOUSE
θ value	8.99809 (rank : 300)	NC score	0.020505 (rank : 257)
Query Neighborhood Hits	303	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TTLL4_MOUSE
θ value	8.99809 (rank : 301)	NC score	0.006806 (rank : 341)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

ZN414_MOUSE
θ value	8.99809 (rank : 302)	NC score	0.006213 (rank : 345)
Query Neighborhood Hits	303	Target Neighborhood Hits	473	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ZN746_HUMAN
θ value	8.99809 (rank : 303)	NC score	-0.004890 (rank : 369)
Query Neighborhood Hits	303	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

ATN1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.065023 (rank : 93)
Query Neighborhood Hits	303	Target Neighborhood Hits	676	Shared Neighborhood Hits	132
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.066548 (rank : 86)
Query Neighborhood Hits	303	Target Neighborhood Hits	931	Shared Neighborhood Hits	142
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.070052 (rank : 76)
Query Neighborhood Hits	303	Target Neighborhood Hits	1537	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CABIN_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.050410 (rank : 161)
Query Neighborhood Hits	303	Target Neighborhood Hits	490	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CGRE1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.053838 (rank : 148)
Query Neighborhood Hits	303	Target Neighborhood Hits	354	Shared Neighborhood Hits	38
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CIZ1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.055154 (rank : 137)
Query Neighborhood Hits	303	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ078_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.054738 (rank : 141)
Query Neighborhood Hits	303	Target Neighborhood Hits	559	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CN032_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.084223 (rank : 53)
Query Neighborhood Hits	303	Target Neighborhood Hits	267	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.079820 (rank : 64)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.058707 (rank : 120)
Query Neighborhood Hits	303	Target Neighborhood Hits	359	Shared Neighborhood Hits	97
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.058789 (rank : 119)
Query Neighborhood Hits	303	Target Neighborhood Hits	356	Shared Neighborhood Hits	96
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CS016_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.055047 (rank : 138)
Query Neighborhood Hits	303	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

ENAH_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.059036 (rank : 116)
Query Neighborhood Hits	303	Target Neighborhood Hits	919	Shared Neighborhood Hits	140
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GGN_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.054291 (rank : 144)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.054486 (rank : 143)
Query Neighborhood Hits	303	Target Neighborhood Hits	311	Shared Neighborhood Hits	95
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GSCR1_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.093547 (rank : 47)
Query Neighborhood Hits	303	Target Neighborhood Hits	674	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KCNK2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.062335 (rank : 102)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.061902 (rank : 103)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.059680 (rank : 113)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.058139 (rank : 122)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK4_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.055553 (rank : 135)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK6_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.061746 (rank : 106)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKA_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.057401 (rank : 125)
Query Neighborhood Hits	303	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKF_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.063899 (rank : 98)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKG_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.051314 (rank : 156)
Query Neighborhood Hits	303	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.095324 (rank : 43)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

MBD6_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.079760 (rank : 65)
Query Neighborhood Hits	303	Target Neighborhood Hits	349	Shared Neighborhood Hits	99
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MUC7_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.082868 (rank : 55)
Query Neighborhood Hits	303	Target Neighborhood Hits	538	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOA6_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.066296 (rank : 88)
Query Neighborhood Hits	303	Target Neighborhood Hits	1076	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PCLO_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.059236 (rank : 114)
Query Neighborhood Hits	303	Target Neighborhood Hits	2046	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRB3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.084019 (rank : 54)
Query Neighborhood Hits	303	Target Neighborhood Hits	318	Shared Neighborhood Hits	101
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.077033 (rank : 67)
Query Neighborhood Hits	303	Target Neighborhood Hits	330	Shared Neighborhood Hits	99
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.064640 (rank : 95)
Query Neighborhood Hits	303	Target Neighborhood Hits	764	Shared Neighborhood Hits	113
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.097190 (rank : 41)
Query Neighborhood Hits	303	Target Neighborhood Hits	385	Shared Neighborhood Hits	125
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.113615 (rank : 39)
Query Neighborhood Hits	303	Target Neighborhood Hits	347	Shared Neighborhood Hits	115
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRP5_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.065396 (rank : 91)
Query Neighborhood Hits	303	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRPC_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.056308 (rank : 130)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

PRR12_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.067361 (rank : 83)
Query Neighborhood Hits	303	Target Neighborhood Hits	460	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RAPH1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.056204 (rank : 131)
Query Neighborhood Hits	303	Target Neighborhood Hits	593	Shared Neighborhood Hits	126
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RERE_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.056918 (rank : 127)
Query Neighborhood Hits	303	Target Neighborhood Hits	779	Shared Neighborhood Hits	133
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.056551 (rank : 129)
Query Neighborhood Hits	303	Target Neighborhood Hits	785	Shared Neighborhood Hits	142
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RPGF4_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.058856 (rank : 117)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

RPGF4_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.061258 (rank : 107)
Query Neighborhood Hits	303	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

SF01_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.050269 (rank : 162)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	92
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF3A2_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.060169 (rank : 112)
Query Neighborhood Hits	303	Target Neighborhood Hits	263	Shared Neighborhood Hits	89
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.056672 (rank : 128)
Query Neighborhood Hits	303	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SFPQ_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.055536 (rank : 136)
Query Neighborhood Hits	303	Target Neighborhood Hits	986	Shared Neighborhood Hits	154
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFR15_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.051884 (rank : 152)
Query Neighborhood Hits	303	Target Neighborhood Hits	368	Shared Neighborhood Hits	78
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SMR3A_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.050699 (rank : 159)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SRRM1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.068949 (rank : 80)
Query Neighborhood Hits	303	Target Neighborhood Hits	690	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.079198 (rank : 66)
Query Neighborhood Hits	303	Target Neighborhood Hits	966	Shared Neighborhood Hits	125
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.064952 (rank : 94)
Query Neighborhood Hits	303	Target Neighborhood Hits	1296	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYN1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.055988 (rank : 132)
Query Neighborhood Hits	303	Target Neighborhood Hits	419	Shared Neighborhood Hits	126
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

T22D2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.053942 (rank : 146)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	80
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TAF4_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.081688 (rank : 57)
Query Neighborhood Hits	303	Target Neighborhood Hits	687	Shared Neighborhood Hits	139
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TARSH_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.051395 (rank : 155)
Query Neighborhood Hits	303	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TAU_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.050259 (rank : 163)
Query Neighborhood Hits	303	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WASIP_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.080191 (rank : 61)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	127
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.074898 (rank : 68)
Query Neighborhood Hits	303	Target Neighborhood Hits	392	Shared Neighborhood Hits	125
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WASL_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.051493 (rank : 154)
Query Neighborhood Hits	303	Target Neighborhood Hits	339	Shared Neighborhood Hits	101
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WBP11_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.066149 (rank : 90)
Query Neighborhood Hits	303	Target Neighborhood Hits	354	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.063298 (rank : 101)
Query Neighborhood Hits	303	Target Neighborhood Hits	362	Shared Neighborhood Hits	99
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.060798 (rank : 110)
Query Neighborhood Hits	303	Target Neighborhood Hits	329	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.060346 (rank : 111)
Query Neighborhood Hits	303	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.057604 (rank : 124)
Query Neighborhood Hits	303	Target Neighborhood Hits	505	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZN207_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.058247 (rank : 121)
Query Neighborhood Hits	303	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

HCN4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	303	Target Neighborhood Hits	303	Shared Neighborhood Hits	303
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HCN4_MOUSE
NC score	0.983167 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	303	Target Neighborhood Hits	284	Shared Neighborhood Hits	184
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HCN1_HUMAN
NC score	0.973135 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN3_MOUSE
NC score	0.972427 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	303	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

HCN3_HUMAN
NC score	0.972279 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	303	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

HCN2_MOUSE
NC score	0.970497 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	121
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HCN1_MOUSE
NC score	0.969226 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	303	Target Neighborhood Hits	172	Shared Neighborhood Hits	63
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

HCN2_HUMAN
NC score	0.966460 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	303	Target Neighborhood Hits	369	Shared Neighborhood Hits	141
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CNGA2_MOUSE
NC score	0.847229 (rank : 9)	θ value	7.77379e-44 (rank : 10)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.841148 (rank : 10)	θ value	2.26182e-43 (rank : 11)
Query Neighborhood Hits	303	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGA1_HUMAN
NC score	0.836991 (rank : 11)	θ value	5.03882e-43 (rank : 12)
Query Neighborhood Hits	303	Target Neighborhood Hits	149	Shared Neighborhood Hits	44
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA1_MOUSE
NC score	0.836030 (rank : 12)	θ value	3.48949e-44 (rank : 9)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGA3_HUMAN
NC score	0.834924 (rank : 13)	θ value	9.50281e-42 (rank : 14)
Query Neighborhood Hits	303	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q16281, Q9UP64	Gene names	CNGA3, CNCG3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

CNGB3_MOUSE
NC score	0.819443 (rank : 14)	θ value	3.06405e-32 (rank : 26)
Query Neighborhood Hits	303	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JJZ9	Gene names	Cngb3, Cng6
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit) (Cyclic nucleotide-gated channel subunit CNG6).

CNGB1_HUMAN
NC score	0.815436 (rank : 15)	θ value	1.9192e-34 (rank : 21)
Query Neighborhood Hits	303	Target Neighborhood Hits	222	Shared Neighborhood Hits	64
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

CNGB3_HUMAN
NC score	0.804977 (rank : 16)	θ value	1.16434e-31 (rank : 27)
Query Neighborhood Hits	303	Target Neighborhood Hits	206	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

KCNH6_HUMAN
NC score	0.794141 (rank : 17)	θ value	5.57106e-42 (rank : 13)
Query Neighborhood Hits	303	Target Neighborhood Hits	222	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH2_MOUSE
NC score	0.792674 (rank : 18)	θ value	1.51715e-39 (rank : 16)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH2_HUMAN
NC score	0.792173 (rank : 19)	θ value	1.98146e-39 (rank : 17)
Query Neighborhood Hits	303	Target Neighborhood Hits	158	Shared Neighborhood Hits	53
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH7_MOUSE
NC score	0.788468 (rank : 20)	θ value	1.3722e-40 (rank : 15)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH7_HUMAN
NC score	0.783640 (rank : 21)	θ value	3.73686e-38 (rank : 18)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH4_HUMAN
NC score	0.780310 (rank : 22)	θ value	1.0531e-32 (rank : 25)
Query Neighborhood Hits	303	Target Neighborhood Hits	177	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH5_MOUSE
NC score	0.777599 (rank : 23)	θ value	5.96599e-36 (rank : 20)
Query Neighborhood Hits	303	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNH5_HUMAN
NC score	0.777496 (rank : 24)	θ value	4.568e-36 (rank : 19)
Query Neighborhood Hits	303	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH8_HUMAN
NC score	0.773961 (rank : 25)	θ value	3.61944e-33 (rank : 24)
Query Neighborhood Hits	303	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH1_MOUSE
NC score	0.772422 (rank : 26)	θ value	3.27365e-34 (rank : 23)
Query Neighborhood Hits	303	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.772109 (rank : 27)	θ value	3.27365e-34 (rank : 22)
Query Neighborhood Hits	303	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH3_HUMAN
NC score	0.765714 (rank : 28)	θ value	1.4233e-29 (rank : 29)
Query Neighborhood Hits	303	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
NC score	0.764495 (rank : 29)	θ value	8.3442e-30 (rank : 28)
Query Neighborhood Hits	303	Target Neighborhood Hits	133	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KAP0_HUMAN
NC score	0.318480 (rank : 30)	θ value	1.29631e-06 (rank : 30)
Query Neighborhood Hits	303	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	P10644, Q567S7	Gene names	PRKAR1A, PKR1, PRKAR1
Domain Architecture
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue- specific extinguisher 1) (TSE1).

KAP0_MOUSE
NC score	0.290288 (rank : 31)	θ value	1.69304e-06 (rank : 31)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DBC7, Q3UKU7, Q9JHR5, Q9JHR6	Gene names	Prkar1a
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type I-alpha regulatory subunit.

KAP1_HUMAN
NC score	0.280795 (rank : 32)	θ value	0.00869519 (rank : 51)
Query Neighborhood Hits	303	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	P31321	Gene names	PRKAR1B
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP1_MOUSE
NC score	0.277857 (rank : 33)	θ value	0.00869519 (rank : 52)
Query Neighborhood Hits	303	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	P12849	Gene names	Prkar1b
Domain Architecture
Description	cAMP-dependent protein kinase type I-beta regulatory subunit.

KAP2_MOUSE
NC score	0.265937 (rank : 34)	θ value	1.43324e-05 (rank : 35)
Query Neighborhood Hits	303	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	P12367	Gene names	Prkar2a
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP2_HUMAN
NC score	0.262039 (rank : 35)	θ value	2.44474e-05 (rank : 36)
Query Neighborhood Hits	303	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	P13861, Q16823	Gene names	PRKAR2A, PKR2, PRKAR2
Domain Architecture
Description	cAMP-dependent protein kinase type II-alpha regulatory subunit.

KAP3_MOUSE
NC score	0.255086 (rank : 36)	θ value	0.00102713 (rank : 46)
Query Neighborhood Hits	303	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	P31324, Q3UTZ1, Q80ZM4, Q8BRZ7	Gene names	Prkar2b
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

KAP3_HUMAN
NC score	0.249600 (rank : 37)	θ value	0.00175202 (rank : 48)
Query Neighborhood Hits	303	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P31323	Gene names	PRKAR2B
Domain Architecture
Description	cAMP-dependent protein kinase type II-beta regulatory subunit.

CT152_MOUSE
NC score	0.161990 (rank : 38)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	303	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D5U8, Q8R083	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf152 homolog.

PRP2_MOUSE
NC score	0.113615 (rank : 39)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	303	Target Neighborhood Hits	347	Shared Neighborhood Hits	115
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

NACAM_MOUSE
NC score	0.102490 (rank : 40)	θ value	0.000461057 (rank : 42)
Query Neighborhood Hits	303	Target Neighborhood Hits	1866	Shared Neighborhood Hits	181
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRP1_HUMAN
NC score	0.097190 (rank : 41)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	303	Target Neighborhood Hits	385	Shared Neighborhood Hits	125
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CT152_HUMAN
NC score	0.095929 (rank : 42)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	303	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q96M20, Q5T3S1, Q9BR36, Q9BWY5	Gene names	C20orf152
Domain Architecture
Description	Uncharacterized protein C20orf152.

KCNKH_HUMAN
NC score	0.095324 (rank : 43)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

BCL9_HUMAN
NC score	0.095134 (rank : 44)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	303	Target Neighborhood Hits	1008	Shared Neighborhood Hits	124
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SRRM2_MOUSE
NC score	0.094546 (rank : 45)	θ value	0.00869519 (rank : 53)
Query Neighborhood Hits	303	Target Neighborhood Hits	1470	Shared Neighborhood Hits	144
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PRRT3_HUMAN
NC score	0.093719 (rank : 46)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	303	Target Neighborhood Hits	998	Shared Neighborhood Hits	119
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

GSCR1_HUMAN
NC score	0.093547 (rank : 47)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	303	Target Neighborhood Hits	674	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

DOT1L_HUMAN
NC score	0.090252 (rank : 48)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	303	Target Neighborhood Hits	660	Shared Neighborhood Hits	87
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

BSN_MOUSE
NC score	0.089784 (rank : 49)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	303	Target Neighborhood Hits	2057	Shared Neighborhood Hits	186
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NCOA6_HUMAN
NC score	0.089523 (rank : 50)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	303	Target Neighborhood Hits	1202	Shared Neighborhood Hits	140
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RGS3_MOUSE
NC score	0.089124 (rank : 51)	θ value	3.77169e-06 (rank : 34)
Query Neighborhood Hits	303	Target Neighborhood Hits	1621	Shared Neighborhood Hits	144
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BCL9_MOUSE
NC score	0.085363 (rank : 52)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	303	Target Neighborhood Hits	770	Shared Neighborhood Hits	117
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CN032_HUMAN
NC score	0.084223 (rank : 53)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	303	Target Neighborhood Hits	267	Shared Neighborhood Hits	97
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

PRB3_HUMAN
NC score	0.084019 (rank : 54)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	303	Target Neighborhood Hits	318	Shared Neighborhood Hits	101
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MUC7_HUMAN
NC score	0.082868 (rank : 55)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	303	Target Neighborhood Hits	538	Shared Neighborhood Hits	119
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OGFR_HUMAN
NC score	0.082232 (rank : 56)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	303	Target Neighborhood Hits	1582	Shared Neighborhood Hits	154
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TAF4_HUMAN
NC score	0.081688 (rank : 57)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	303	Target Neighborhood Hits	687	Shared Neighborhood Hits	139
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

KGP1B_MOUSE
NC score	0.080994 (rank : 58)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	303	Target Neighborhood Hits	922	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_HUMAN
NC score	0.080970 (rank : 59)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	303	Target Neighborhood Hits	921	Shared Neighborhood Hits	62
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1A_HUMAN
NC score	0.080628 (rank : 60)	θ value	0.000270298 (rank : 39)
Query Neighborhood Hits	303	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

WASIP_HUMAN
NC score	0.080191 (rank : 61)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	303	Target Neighborhood Hits	458	Shared Neighborhood Hits	127
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

KGP2_MOUSE
NC score	0.080113 (rank : 62)	θ value	1.69304e-06 (rank : 32)
Query Neighborhood Hits	303	Target Neighborhood Hits	1029	Shared Neighborhood Hits	54
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.080048 (rank : 63)	θ value	2.21117e-06 (rank : 33)
Query Neighborhood Hits	303	Target Neighborhood Hits	1023	Shared Neighborhood Hits	56
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

CN032_MOUSE
NC score	0.079820 (rank : 64)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

MBD6_HUMAN
NC score	0.079760 (rank : 65)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	303	Target Neighborhood Hits	349	Shared Neighborhood Hits	99
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

SRRM1_MOUSE
NC score	0.079198 (rank : 66)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	303	Target Neighborhood Hits	966	Shared Neighborhood Hits	125
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PRB4S_HUMAN
NC score	0.077033 (rank : 67)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	303	Target Neighborhood Hits	330	Shared Neighborhood Hits	99
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

WASIP_MOUSE
NC score	0.074898 (rank : 68)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	303	Target Neighborhood Hits	392	Shared Neighborhood Hits	125
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MAGE1_HUMAN
NC score	0.073745 (rank : 69)	θ value	0.000786445 (rank : 44)
Query Neighborhood Hits	303	Target Neighborhood Hits	1389	Shared Neighborhood Hits	160
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CIC_HUMAN
NC score	0.072989 (rank : 70)	θ value	1.81305 (rank : 149)
Query Neighborhood Hits	303	Target Neighborhood Hits	992	Shared Neighborhood Hits	146
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SC24C_HUMAN
NC score	0.072273 (rank : 71)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	303	Target Neighborhood Hits	662	Shared Neighborhood Hits	99
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

CBP_HUMAN
NC score	0.072213 (rank : 72)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	303	Target Neighborhood Hits	941	Shared Neighborhood Hits	141
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MISS_MOUSE
NC score	0.072088 (rank : 73)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	303	Target Neighborhood Hits	444	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

RGS3_HUMAN
NC score	0.071051 (rank : 74)	θ value	0.00665767 (rank : 50)
Query Neighborhood Hits	303	Target Neighborhood Hits	1375	Shared Neighborhood Hits	110
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MDC1_MOUSE
NC score	0.070187 (rank : 75)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	303	Target Neighborhood Hits	998	Shared Neighborhood Hits	106
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

BSN_HUMAN
NC score	0.070052 (rank : 76)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	303	Target Neighborhood Hits	1537	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SAPS1_HUMAN
NC score	0.069754 (rank : 77)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	303	Target Neighborhood Hits	704	Shared Neighborhood Hits	105
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ZN750_MOUSE
NC score	0.069312 (rank : 78)	θ value	0.00869519 (rank : 55)
Query Neighborhood Hits	303	Target Neighborhood Hits	346	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

MUC1_HUMAN
NC score	0.069269 (rank : 79)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	303	Target Neighborhood Hits	975	Shared Neighborhood Hits	117
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SRRM1_HUMAN
NC score	0.068949 (rank : 80)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	303	Target Neighborhood Hits	690	Shared Neighborhood Hits	110
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

MLL3_HUMAN
NC score	0.068516 (rank : 81)	θ value	0.0113563 (rank : 56)
Query Neighborhood Hits	303	Target Neighborhood Hits	1644	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_MOUSE
NC score	0.068072 (rank : 82)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	303	Target Neighborhood Hits	2275	Shared Neighborhood Hits	187
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRR12_HUMAN
NC score	0.067361 (rank : 83)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	303	Target Neighborhood Hits	460	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

BAT3_MOUSE
NC score	0.067307 (rank : 84)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	303	Target Neighborhood Hits	518	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

EP300_HUMAN
NC score	0.066751 (rank : 85)	θ value	0.0563607 (rank : 69)
Query Neighborhood Hits	303	Target Neighborhood Hits	821	Shared Neighborhood Hits	130
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BAT2_HUMAN
NC score	0.066548 (rank : 86)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	303	Target Neighborhood Hits	931	Shared Neighborhood Hits	142
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CBP_MOUSE
NC score	0.066538 (rank : 87)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	303	Target Neighborhood Hits	1051	Shared Neighborhood Hits	133
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NCOA6_MOUSE
NC score	0.066296 (rank : 88)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	303	Target Neighborhood Hits	1076	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MUCDL_HUMAN
NC score	0.066203 (rank : 89)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	303	Target Neighborhood Hits	777	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

WBP11_HUMAN
NC score	0.066149 (rank : 90)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	303	Target Neighborhood Hits	354	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

PRP5_HUMAN
NC score	0.065396 (rank : 91)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	303	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

R3HD2_MOUSE
NC score	0.065284 (rank : 92)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	303	Target Neighborhood Hits	397	Shared Neighborhood Hits	64
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

ATN1_HUMAN
NC score	0.065023 (rank : 93)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	303	Target Neighborhood Hits	676	Shared Neighborhood Hits	132
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SRRM2_HUMAN
NC score	0.064952 (rank : 94)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	303	Target Neighborhood Hits	1296	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PRG4_HUMAN
NC score	0.064640 (rank : 95)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	303	Target Neighborhood Hits	764	Shared Neighborhood Hits	113
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

EPN3_HUMAN
NC score	0.064193 (rank : 96)	θ value	0.00134147 (rank : 47)
Query Neighborhood Hits	303	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PI5PA_HUMAN
NC score	0.063913 (rank : 97)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	303	Target Neighborhood Hits	749	Shared Neighborhood Hits	116
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

KCNKF_HUMAN
NC score	0.063899 (rank : 98)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	303	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

ALEX_HUMAN
NC score	0.063741 (rank : 99)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	303	Target Neighborhood Hits	361	Shared Neighborhood Hits	81
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MLL2_HUMAN
NC score	0.063343 (rank : 100)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	303	Target Neighborhood Hits	1788	Shared Neighborhood Hits	173
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

WBP11_MOUSE
NC score	0.063298 (rank : 101)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	303	Target Neighborhood Hits	362	Shared Neighborhood Hits	99
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

KCNK2_HUMAN
NC score	0.062335 (rank : 102)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	303	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNK2_MOUSE
NC score	0.061902 (rank : 103)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

BAT2_MOUSE
NC score	0.061863 (rank : 104)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	303	Target Neighborhood Hits	947	Shared Neighborhood Hits	140
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FA8A1_HUMAN
NC score	0.061862 (rank : 105)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	303	Target Neighborhood Hits	53	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

KCNK6_HUMAN
NC score	0.061746 (rank : 106)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	303	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

RPGF4_MOUSE
NC score	0.061258 (rank : 107)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	303	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQZ6, Q8VIP9, Q9CW52, Q9Z1P0	Gene names	Rapgef4, Cgef2, Epac2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2) (cAMP-dependent Rap1 guanine-nucleotide exchange factor).

DIDO1_HUMAN
NC score	0.061212 (rank : 108)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	303	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SON_HUMAN
NC score	0.060822 (rank : 109)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	303	Target Neighborhood Hits	1568	Shared Neighborhood Hits	137
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

WIRE_HUMAN
NC score	0.060798 (rank : 110)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	303	Target Neighborhood Hits	329	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
NC score	0.060346 (rank : 111)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	303	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

SF3A2_HUMAN
NC score	0.060169 (rank : 112)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	303	Target Neighborhood Hits	263	Shared Neighborhood Hits	89
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

KCNK3_HUMAN
NC score	0.059680 (rank : 113)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

PCLO_HUMAN
NC score	0.059236 (rank : 114)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	303	Target Neighborhood Hits	2046	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TCGAP_HUMAN
NC score	0.059169 (rank : 115)	θ value	5.44631e-05 (rank : 37)
Query Neighborhood Hits	303	Target Neighborhood Hits	872	Shared Neighborhood Hits	101
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ENAH_MOUSE
NC score	0.059036 (rank : 116)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	303	Target Neighborhood Hits	919	Shared Neighborhood Hits	140
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

RPGF4_HUMAN
NC score	0.058856 (rank : 117)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	303	Target Neighborhood Hits	88	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WZA2, O95636, Q8IXK6, Q8TAA4	Gene names	RAPGEF4, CGEF2, EPAC2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 4 (cAMP-regulated guanine nucleotide exchange factor II) (cAMP-GEFII) (Exchange factor directly activated by cAMP 2) (Epac 2).

SSBP4_HUMAN
NC score	0.058843 (rank : 118)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	303	Target Neighborhood Hits	753	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CPSF6_MOUSE
NC score	0.058789 (rank : 119)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	303	Target Neighborhood Hits	356	Shared Neighborhood Hits	96
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.058707 (rank : 120)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	303	Target Neighborhood Hits	359	Shared Neighborhood Hits	97
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

ZN207_HUMAN
NC score	0.058247 (rank : 121)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	303	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

KCNK3_MOUSE
NC score	0.058139 (rank : 122)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

MDC1_HUMAN
NC score	0.057648 (rank : 123)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	303	Target Neighborhood Hits	1446	Shared Neighborhood Hits	115
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

YLPM1_MOUSE
NC score	0.057604 (rank : 124)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	303	Target Neighborhood Hits	505	Shared Neighborhood Hits	112
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

KCNKA_HUMAN
NC score	0.057401 (rank : 125)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	303	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

NCOR2_MOUSE
NC score	0.057056 (rank : 126)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	303	Target Neighborhood Hits	790	Shared Neighborhood Hits	79
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RERE_HUMAN
NC score	0.056918 (rank : 127)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	303	Target Neighborhood Hits	779	Shared Neighborhood Hits	133
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SF3A2_MOUSE
NC score	0.056672 (rank : 128)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	303	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

RERE_MOUSE
NC score	0.056551 (rank : 129)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	303	Target Neighborhood Hits	785	Shared Neighborhood Hits	142
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRPC_HUMAN
NC score	0.056308 (rank : 130)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	P02810, Q4VBP2, Q53XA2, Q6P2F6	Gene names	PRH1
Domain Architecture	No domain graphic available
Description	Salivary acidic proline-rich phosphoprotein 1/2 precursor (PRP-1/PRP- 2) (Parotid proline-rich protein 1/2) (Pr1/Pr2) (Protein C) (Parotid acidic protein) (Pa) (Parotid isoelectric focusing variant protein) (PIF-S) (Parotid double-band protein) (Db-s) [Contains: Salivary acidic proline-rich phosphoprotein 1/2; Salivary acidic proline-rich phosphoprotein 3/4 (PRP-3/PRP-4) (Protein A) (PIF-F) (Db-F); Peptide P-C].

RAPH1_HUMAN
NC score	0.056204 (rank : 131)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	303	Target Neighborhood Hits	593	Shared Neighborhood Hits	126
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SYN1_HUMAN
NC score	0.055988 (rank : 132)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	303	Target Neighborhood Hits	419	Shared Neighborhood Hits	126
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

EPN3_MOUSE
NC score	0.055677 (rank : 133)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	303	Target Neighborhood Hits	312	Shared Neighborhood Hits	56
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

CRSP2_HUMAN
NC score	0.055559 (rank : 134)	θ value	2.36792 (rank : 173)
Query Neighborhood Hits	303	Target Neighborhood Hits	380	Shared Neighborhood Hits	66
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

KCNK4_HUMAN
NC score	0.055553 (rank : 135)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	303	Target Neighborhood Hits	109	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

SFPQ_HUMAN
NC score	0.055536 (rank : 136)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	303	Target Neighborhood Hits	986	Shared Neighborhood Hits	154
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CIZ1_HUMAN
NC score	0.055154 (rank : 137)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	303	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CS016_HUMAN
NC score	0.055047 (rank : 138)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	303	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

BAT3_HUMAN
NC score	0.054824 (rank : 139)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	303	Target Neighborhood Hits	490	Shared Neighborhood Hits	83
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CIC_MOUSE
NC score	0.054741 (rank : 140)	θ value	0.21417 (rank : 85)
Query Neighborhood Hits	303	Target Neighborhood Hits	742	Shared Neighborhood Hits	134
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ078_MOUSE
NC score	0.054738 (rank : 141)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	303	Target Neighborhood Hits	559	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MLL3_MOUSE
NC score	0.054536 (rank : 142)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	303	Target Neighborhood Hits	1399	Shared Neighborhood Hits	127
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

GGN_MOUSE
NC score	0.054486 (rank : 143)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	303	Target Neighborhood Hits	311	Shared Neighborhood Hits	95
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GGN_HUMAN
NC score	0.054291 (rank : 144)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	77
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NCOR2_HUMAN
NC score	0.054259 (rank : 145)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	303	Target Neighborhood Hits	870	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

T22D2_HUMAN
NC score	0.053942 (rank : 146)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	303	Target Neighborhood Hits	250	Shared Neighborhood Hits	80
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PDZD2_HUMAN
NC score	0.053919 (rank : 147)	θ value	0.0961366 (rank : 79)
Query Neighborhood Hits	303	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CGRE1_HUMAN
NC score	0.053838 (rank : 148)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	303	Target Neighborhood Hits	354	Shared Neighborhood Hits	38
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

HAIR_HUMAN
NC score	0.053050 (rank : 149)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	303	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

HRBL_MOUSE
NC score	0.052558 (rank : 150)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	303	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ZN385_HUMAN
NC score	0.052118 (rank : 151)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	303	Target Neighborhood Hits	614	Shared Neighborhood Hits	72
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SFR15_HUMAN
NC score	0.051884 (rank : 152)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	303	Target Neighborhood Hits	368	Shared Neighborhood Hits	78
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TPO_MOUSE
NC score	0.051798 (rank : 153)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	33
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

WASL_MOUSE
NC score	0.051493 (rank : 154)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	303	Target Neighborhood Hits	339	Shared Neighborhood Hits	101
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

TARSH_HUMAN
NC score	0.051395 (rank : 155)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	303	Target Neighborhood Hits	768	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

KCNKG_HUMAN
NC score	0.051314 (rank : 156)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	303	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

ZIMP7_MOUSE
NC score	0.051120 (rank : 157)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	303	Target Neighborhood Hits	566	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

CRTC1_HUMAN
NC score	0.051033 (rank : 158)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	303	Target Neighborhood Hits	319	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

SMR3A_HUMAN
NC score	0.050699 (rank : 159)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	303	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SPT5H_MOUSE
NC score	0.050489 (rank : 160)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	303	Target Neighborhood Hits	437	Shared Neighborhood Hits	65
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

CABIN_HUMAN
NC score	0.050410 (rank : 161)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	303	Target Neighborhood Hits	490	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SF01_HUMAN
NC score	0.050269 (rank : 162)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	303	Target Neighborhood Hits	287	Shared Neighborhood Hits	92
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

TAU_MOUSE
NC score	0.050259 (rank : 163)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	303	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

NFH_MOUSE
NC score	0.050190 (rank : 164)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	303	Target Neighborhood Hits	2247	Shared Neighborhood Hits	150
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SPT5H_HUMAN
NC score	0.049937 (rank : 165)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	303	Target Neighborhood Hits	436	Shared Neighborhood Hits	65
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

S23IP_MOUSE
NC score	0.048976 (rank : 166)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	303	Target Neighborhood Hits	363	Shared Neighborhood Hits	62
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

ZIM10_HUMAN
NC score	0.048890 (rank : 167)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	303	Target Neighborhood Hits	577	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MILK1_MOUSE
NC score	0.048869 (rank : 168)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	303	Target Neighborhood Hits	788	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TARA_HUMAN
NC score	0.048117 (rank : 169)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	303	Target Neighborhood Hits	1626	Shared Neighborhood Hits	120
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

T22D4_HUMAN
NC score	0.047423 (rank : 170)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	303	Target Neighborhood Hits	403	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

ARI1A_HUMAN
NC score	0.047334 (rank : 171)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	303	Target Neighborhood Hits	787	Shared Neighborhood Hits	118
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

TGON2_HUMAN
NC score	0.046368 (rank : 172)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	303	Target Neighborhood Hits	1037	Shared Neighborhood Hits	88
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

MINT_MOUSE
NC score	0.046352 (rank : 173)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	303	Target Neighborhood Hits	1514	Shared Neighborhood Hits	115
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

JPH2_HUMAN
NC score	0.046338 (rank : 174)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	303	Target Neighborhood Hits	639	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LR37A_HUMAN
NC score	0.046201 (rank : 175)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	303	Target Neighborhood Hits	720	Shared Neighborhood Hits	65
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CEP68_HUMAN
NC score	0.045691 (rank : 176)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	303	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

IASPP_MOUSE
NC score	0.044273 (rank : 177)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	303	Target Neighborhood Hits	1024	Shared Neighborhood Hits	101
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TAU_HUMAN
NC score	0.044184 (rank : 178)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	303	Target Neighborhood Hits	448	Shared Neighborhood Hits	84
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CI079_HUMAN
NC score	0.043841 (rank : 179)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	303	Target Neighborhood Hits	288	Shared Neighborhood Hits	50
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

MKL1_MOUSE
NC score	0.043829 (rank : 180)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	303	Target Neighborhood Hits	667	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NRX2B_HUMAN
NC score	0.043507 (rank : 181)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	303	Target Neighborhood Hits	481	Shared Neighborhood Hits	63
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SC24A_MOUSE
NC score	0.043398 (rank : 182)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	303	Target Neighborhood Hits	394	Shared Neighborhood Hits	66
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

MAVS_HUMAN
NC score	0.042866 (rank : 183)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SYNJ1_HUMAN
NC score	0.042852 (rank : 184)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	303	Target Neighborhood Hits	498	Shared Neighborhood Hits	110
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CAC1G_HUMAN
NC score	0.042849 (rank : 185)	θ value	0.000461057 (rank : 41)
Query Neighborhood Hits	303	Target Neighborhood Hits	587	Shared Neighborhood Hits	72
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KCNK1_MOUSE
NC score	0.041358 (rank : 186)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	303	Target Neighborhood Hits	70	Shared Neighborhood Hits	19
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

SON_MOUSE
NC score	0.041251 (rank : 187)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	303	Target Neighborhood Hits	957	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

DCNP1_HUMAN
NC score	0.041250 (rank : 188)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	303	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TF63	Gene names	DCNP1, C5orf20
Domain Architecture	No domain graphic available
Description	Dendritic cell nuclear protein 1.

KCNK1_HUMAN
NC score	0.040450 (rank : 189)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	303	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

K1683_HUMAN
NC score	0.039863 (rank : 190)	θ value	0.62314 (rank : 116)
Query Neighborhood Hits	303	Target Neighborhood Hits	240	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

NCOA2_HUMAN
NC score	0.038857 (rank : 191)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	303	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PER3_HUMAN
NC score	0.038637 (rank : 192)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	303	Target Neighborhood Hits	479	Shared Neighborhood Hits	72
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

IF4G1_MOUSE
NC score	0.038624 (rank : 193)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	303	Target Neighborhood Hits	534	Shared Neighborhood Hits	82
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

CECR2_HUMAN
NC score	0.038271 (rank : 194)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	303	Target Neighborhood Hits	543	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ZIM10_MOUSE
NC score	0.037675 (rank : 195)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	303	Target Neighborhood Hits	430	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

K1802_MOUSE
NC score	0.037637 (rank : 196)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	303	Target Neighborhood Hits	1596	Shared Neighborhood Hits	128
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PP14A_MOUSE
NC score	0.037233 (rank : 197)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	303	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91VC7, Q99MB9	Gene names	Ppp1r14a, Cpi17
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14A (17 kDa PKC-potentiated inhibitory protein of PP1) (CPI-17).

MEF2D_HUMAN
NC score	0.037208 (rank : 198)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

CSF1_HUMAN
NC score	0.037149 (rank : 199)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	303	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

ZN598_HUMAN
NC score	0.036950 (rank : 200)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	303	Target Neighborhood Hits	339	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

COIA1_HUMAN
NC score	0.035856 (rank : 201)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	303	Target Neighborhood Hits	447	Shared Neighborhood Hits	89
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MEF2D_MOUSE
NC score	0.035343 (rank : 202)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

CO5A2_HUMAN
NC score	0.034936 (rank : 203)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	303	Target Neighborhood Hits	760	Shared Neighborhood Hits	101
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

RUSC2_MOUSE
NC score	0.034796 (rank : 204)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	303	Target Neighborhood Hits	305	Shared Neighborhood Hits	58
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CBL_MOUSE
NC score	0.034543 (rank : 205)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	303	Target Neighborhood Hits	426	Shared Neighborhood Hits	36
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CSKI1_HUMAN
NC score	0.033920 (rank : 206)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	303	Target Neighborhood Hits	997	Shared Neighborhood Hits	130
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ARID2_HUMAN
NC score	0.033482 (rank : 207)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	303	Target Neighborhood Hits	302	Shared Neighborhood Hits	40
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

RUNX3_MOUSE
NC score	0.033229 (rank : 208)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	303	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q64131, Q99P92, Q9R199	Gene names	Runx3, Aml2, Cbfa3, Pebp2a3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

CSKI1_MOUSE
NC score	0.033018 (rank : 209)	θ value	1.81305 (rank : 150)
Query Neighborhood Hits	303	Target Neighborhood Hits	1031	Shared Neighborhood Hits	125
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HTRA4_HUMAN
NC score	0.032995 (rank : 210)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

RP1L1_HUMAN
NC score	0.032697 (rank : 211)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	303	Target Neighborhood Hits	1072	Shared Neighborhood Hits	103
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RUNX3_HUMAN
NC score	0.032403 (rank : 212)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	303	Target Neighborhood Hits	96	Shared Neighborhood Hits	19
SwissProt Accessions	Q13761, Q12969, Q13760	Gene names	RUNX3, AML2, CBFA3, PEBP2A3
Domain Architecture
Description	Runt-related transcription factor 3 (Core-binding factor, alpha 3 subunit) (CBF-alpha 3) (Acute myeloid leukemia 2 protein) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEBP2-alpha C) (PEA2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit).

K1543_MOUSE
NC score	0.031483 (rank : 213)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	303	Target Neighborhood Hits	497	Shared Neighborhood Hits	69
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MEGF9_MOUSE
NC score	0.031269 (rank : 214)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MAGD4_HUMAN
NC score	0.031095 (rank : 215)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	303	Target Neighborhood Hits	338	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

LPP_HUMAN
NC score	0.030758 (rank : 216)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	303	Target Neighborhood Hits	775	Shared Neighborhood Hits	87
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

DMRTD_HUMAN
NC score	0.030578 (rank : 217)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	303	Target Neighborhood Hits	216	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

BIN1_HUMAN
NC score	0.030029 (rank : 218)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	303	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

GNAS1_HUMAN
NC score	0.029225 (rank : 219)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	64
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CBL_HUMAN
NC score	0.029189 (rank : 220)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	303	Target Neighborhood Hits	353	Shared Neighborhood Hits	29
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

S5A2_HUMAN
NC score	0.029129 (rank : 221)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	303	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	P31213, Q9BYE6	Gene names	SRD5A2
Domain Architecture
Description	3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5- alpha-reductase 2) (SR type 2) (5 alpha-SR2) (Type II 5-alpha reductase).

JIP1_HUMAN
NC score	0.028907 (rank : 222)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	303	Target Neighborhood Hits	271	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

CAC1H_HUMAN
NC score	0.028504 (rank : 223)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	303	Target Neighborhood Hits	307	Shared Neighborhood Hits	39
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

FHOD1_MOUSE
NC score	0.028473 (rank : 224)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	303	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

NRX2A_HUMAN
NC score	0.028204 (rank : 225)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	303	Target Neighborhood Hits	614	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TLE1_HUMAN
NC score	0.027852 (rank : 226)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	303	Target Neighborhood Hits	485	Shared Neighborhood Hits	40
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

TLE1_MOUSE
NC score	0.027833 (rank : 227)	θ value	0.00869519 (rank : 54)
Query Neighborhood Hits	303	Target Neighborhood Hits	491	Shared Neighborhood Hits	39
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

LSD1_HUMAN
NC score	0.027650 (rank : 228)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	303	Target Neighborhood Hits	455	Shared Neighborhood Hits	38
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

AFF2_MOUSE
NC score	0.027570 (rank : 229)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	303	Target Neighborhood Hits	225	Shared Neighborhood Hits	27
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

ZCH11_HUMAN
NC score	0.027568 (rank : 230)	θ value	0.365318 (rank : 103)
Query Neighborhood Hits	303	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TAX3, Q12764, Q5TAX4, Q86XZ3	Gene names	ZCCHC11, KIAA0191
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 11.

NFRKB_HUMAN
NC score	0.027309 (rank : 231)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	303	Target Neighborhood Hits	211	Shared Neighborhood Hits	43
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RP3A_MOUSE
NC score	0.027266 (rank : 232)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	303	Target Neighborhood Hits	510	Shared Neighborhood Hits	74
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BCOR_HUMAN
NC score	0.027016 (rank : 233)	θ value	1.38821 (rank : 136)
Query Neighborhood Hits	303	Target Neighborhood Hits	609	Shared Neighborhood Hits	44
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BAZ2A_MOUSE
NC score	0.026231 (rank : 234)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	303	Target Neighborhood Hits	744	Shared Neighborhood Hits	73
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PHLPP_HUMAN
NC score	0.026189 (rank : 235)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	303	Target Neighborhood Hits	604	Shared Neighborhood Hits	69
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

NUMBL_HUMAN
NC score	0.026087 (rank : 236)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	303	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

MTSS1_HUMAN
NC score	0.025953 (rank : 237)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	303	Target Neighborhood Hits	504	Shared Neighborhood Hits	56
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

EHMT2_MOUSE
NC score	0.025534 (rank : 238)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	303	Target Neighborhood Hits	750	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

RNF25_HUMAN
NC score	0.025398 (rank : 239)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	303	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

REC8L_MOUSE
NC score	0.025150 (rank : 240)	θ value	0.47712 (rank : 107)
Query Neighborhood Hits	303	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5S7, Q3UIN9, Q9JK52	Gene names	Rec8L1, Rec8
Domain Architecture
Description	Meiotic recombination protein REC8-like 1 (Cohesin Rec8p).

ELOA2_HUMAN
NC score	0.024844 (rank : 241)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

CO4A1_MOUSE
NC score	0.024427 (rank : 242)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	303	Target Neighborhood Hits	450	Shared Neighborhood Hits	85
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

DEN1A_HUMAN
NC score	0.024332 (rank : 243)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	303	Target Neighborhood Hits	176	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ZN409_HUMAN
NC score	0.024285 (rank : 244)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	303	Target Neighborhood Hits	842	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

CTND2_HUMAN
NC score	0.023749 (rank : 245)	θ value	2.36792 (rank : 174)
Query Neighborhood Hits	303	Target Neighborhood Hits	333	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

NU133_HUMAN
NC score	0.023358 (rank : 246)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	303	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WUM0, Q9H9W2, Q9NV71, Q9NVC4	Gene names	NUP133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

CO7A1_HUMAN
NC score	0.023297 (rank : 247)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	303	Target Neighborhood Hits	807	Shared Neighborhood Hits	99
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

PGCA_MOUSE
NC score	0.022933 (rank : 248)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	303	Target Neighborhood Hits	643	Shared Neighborhood Hits	49
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

K0056_HUMAN
NC score	0.022661 (rank : 249)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	303	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

IQEC3_MOUSE
NC score	0.022343 (rank : 250)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	303	Target Neighborhood Hits	274	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CO9A1_MOUSE
NC score	0.021875 (rank : 251)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	303	Target Neighborhood Hits	477	Shared Neighborhood Hits	69
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CAC1H_MOUSE
NC score	0.021713 (rank : 252)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	303	Target Neighborhood Hits	230	Shared Neighborhood Hits	31
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

RUSC2_HUMAN
NC score	0.021616 (rank : 253)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	303	Target Neighborhood Hits	205	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

F100B_MOUSE
NC score	0.021027 (rank : 254)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	303	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

TLE3_MOUSE
NC score	0.020976 (rank : 255)	θ value	0.47712 (rank : 110)
Query Neighborhood Hits	303	Target Neighborhood Hits	378	Shared Neighborhood Hits	22
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

CTND2_MOUSE
NC score	0.020770 (rank : 256)	θ value	0.62314 (rank : 115)
Query Neighborhood Hits	303	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

TCRG1_MOUSE
NC score	0.020505 (rank : 257)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	303	Target Neighborhood Hits	947	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

RNF25_MOUSE
NC score	0.020149 (rank : 258)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	303	Target Neighborhood Hits	106	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

CO9A1_HUMAN
NC score	0.020112 (rank : 259)	θ value	0.47712 (rank : 106)
Query Neighborhood Hits	303	Target Neighborhood Hits	420	Shared Neighborhood Hits	58
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

ZN687_HUMAN
NC score	0.020112 (rank : 260)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	303	Target Neighborhood Hits	1244	Shared Neighborhood Hits	97
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CJ108_HUMAN
NC score	0.019609 (rank : 261)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	303	Target Neighborhood Hits	165	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

ACD_HUMAN
NC score	0.019601 (rank : 262)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	303	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

B4GT1_HUMAN
NC score	0.019541 (rank : 263)	θ value	2.36792 (rank : 169)
Query Neighborhood Hits	303	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SEM6C_MOUSE
NC score	0.019460 (rank : 264)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	303	Target Neighborhood Hits	352	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

NSD1_MOUSE
NC score	0.019374 (rank : 265)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	303	Target Neighborhood Hits	472	Shared Neighborhood Hits	47
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SPEG_MOUSE
NC score	0.018841 (rank : 266)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	303	Target Neighborhood Hits	1959	Shared Neighborhood Hits	132
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CAC1B_MOUSE
NC score	0.018816 (rank : 267)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	303	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TLE3_HUMAN
NC score	0.018779 (rank : 268)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	303	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

CD248_MOUSE
NC score	0.018773 (rank : 269)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	303	Target Neighborhood Hits	578	Shared Neighborhood Hits	51
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GMEB2_HUMAN
NC score	0.018627 (rank : 270)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	303	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

THAP7_HUMAN
NC score	0.018345 (rank : 271)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	303	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BT49	Gene names	THAP7
Domain Architecture
Description	THAP domain-containing protein 7.

THAP7_MOUSE
NC score	0.018250 (rank : 272)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	303	Target Neighborhood Hits	64	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VCZ3	Gene names	Thap7
Domain Architecture
Description	THAP domain-containing protein 7.

BCAR1_HUMAN
NC score	0.018233 (rank : 273)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	303	Target Neighborhood Hits	554	Shared Neighborhood Hits	58
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

K0323_HUMAN
NC score	0.018007 (rank : 274)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	303	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O15037, Q86TZ6, Q8IUQ2, Q96BA9	Gene names	KIAA0323
Domain Architecture	No domain graphic available
Description	Protein KIAA0323.

BCOR_MOUSE
NC score	0.017774 (rank : 275)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	303	Target Neighborhood Hits	521	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

INVS_MOUSE
NC score	0.017695 (rank : 276)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	303	Target Neighborhood Hits	609	Shared Neighborhood Hits	58
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

CO4A2_HUMAN
NC score	0.017000 (rank : 277)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	303	Target Neighborhood Hits	454	Shared Neighborhood Hits	66
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

ZN516_MOUSE
NC score	0.016132 (rank : 278)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	303	Target Neighborhood Hits	1197	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ARNT_MOUSE
NC score	0.015802 (rank : 279)	θ value	1.38821 (rank : 135)
Query Neighborhood Hits	303	Target Neighborhood Hits	213	Shared Neighborhood Hits	25
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

FOG1_MOUSE
NC score	0.015557 (rank : 280)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	303	Target Neighborhood Hits	1237	Shared Neighborhood Hits	99
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PYR1_HUMAN
NC score	0.015491 (rank : 281)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	P27708, Q6P0Q0	Gene names	CAD
Domain Architecture	No domain graphic available
Description	CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)].

ZDHC8_HUMAN
NC score	0.015469 (rank : 282)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	303	Target Neighborhood Hits	234	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

BCL7C_MOUSE
NC score	0.015252 (rank : 283)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	303	Target Neighborhood Hits	170	Shared Neighborhood Hits	30
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

SC6A5_MOUSE
NC score	0.015153 (rank : 284)	θ value	0.47712 (rank : 109)
Query Neighborhood Hits	303	Target Neighborhood Hits	135	Shared Neighborhood Hits	22
SwissProt Accessions	Q761V0, Q8CFM5, Q91ZQ2	Gene names	Slc6a5, Glyt2
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

DCC_MOUSE
NC score	0.014987 (rank : 285)	θ value	2.36792 (rank : 175)
Query Neighborhood Hits	303	Target Neighborhood Hits	896	Shared Neighborhood Hits	49
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

NCOA1_HUMAN
NC score	0.014707 (rank : 286)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	303	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

IF4B_HUMAN
NC score	0.014415 (rank : 287)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	303	Target Neighborhood Hits	417	Shared Neighborhood Hits	35
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KCNS3_HUMAN
NC score	0.014412 (rank : 288)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	303	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

FRS3_HUMAN
NC score	0.014267 (rank : 289)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	303	Target Neighborhood Hits	76	Shared Neighborhood Hits	11
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

PKHA6_HUMAN
NC score	0.014242 (rank : 290)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	303	Target Neighborhood Hits	556	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

JIP3_HUMAN
NC score	0.014214 (rank : 291)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	303	Target Neighborhood Hits	1039	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

FILA_HUMAN
NC score	0.013863 (rank : 292)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	303	Target Neighborhood Hits	685	Shared Neighborhood Hits	33
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TSH1_MOUSE
NC score	0.013687 (rank : 293)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	303	Target Neighborhood Hits	675	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

PUNC_MOUSE
NC score	0.013658 (rank : 294)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	303	Target Neighborhood Hits	501	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ARHG1_MOUSE
NC score	0.013518 (rank : 295)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	303	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	Q61210, O89074, Q80YE8, Q80YE9, Q91VL3	Gene names	Arhgef1, Lbcl2, Lsc
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (Lymphoid blast crisis-like 2) (Lbc's second cousin).

ULK1_HUMAN
NC score	0.013462 (rank : 296)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	303	Target Neighborhood Hits	1121	Shared Neighborhood Hits	69
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

TFE2_HUMAN
NC score	0.013399 (rank : 297)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

ULK1_MOUSE
NC score	0.013096 (rank : 298)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	303	Target Neighborhood Hits	1214	Shared Neighborhood Hits	73
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

CAMKV_HUMAN
NC score	0.012848 (rank : 299)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	303	Target Neighborhood Hits	1084	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

CCR3_MOUSE
NC score	0.012658 (rank : 300)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	303	Target Neighborhood Hits	781	Shared Neighborhood Hits	11
SwissProt Accessions	P51678	Gene names	Ccr3, Cmkbr1l2, Cmkbr3
Domain Architecture
Description	Probable C-C chemokine receptor type 3 (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR3) (Macrophage inflammatory protein 1-alpha receptor-like 2) (MIP-1 alpha RL2) (CD193 antigen).

MARK2_HUMAN
NC score	0.012512 (rank : 301)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	303	Target Neighborhood Hits	1056	Shared Neighborhood Hits	52
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

RB_HUMAN
NC score	0.012415 (rank : 302)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	303	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P06400, P78499, Q5VW46, Q8IZL4	Gene names	RB1
Domain Architecture
Description	Retinoblastoma-associated protein (PP110) (P105-RB) (RB).

PKHA5_HUMAN
NC score	0.012277 (rank : 303)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	303	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

FOXN4_MOUSE
NC score	0.012160 (rank : 304)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	303	Target Neighborhood Hits	154	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

ZDH14_HUMAN
NC score	0.012139 (rank : 305)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

GAB2_HUMAN
NC score	0.011780 (rank : 306)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	303	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

PKN3_MOUSE
NC score	0.011512 (rank : 307)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	303	Target Neighborhood Hits	1009	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

SETX_HUMAN
NC score	0.011218 (rank : 308)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	303	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

AATK_HUMAN
NC score	0.011104 (rank : 309)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	303	Target Neighborhood Hits	1243	Shared Neighborhood Hits	89
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TRIM8_HUMAN
NC score	0.010952 (rank : 310)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	303	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TACC2_HUMAN
NC score	0.010654 (rank : 311)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	303	Target Neighborhood Hits	856	Shared Neighborhood Hits	51
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

RECQ5_HUMAN
NC score	0.010556 (rank : 312)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	303	Target Neighborhood Hits	390	Shared Neighborhood Hits	39
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

PYGO1_HUMAN
NC score	0.010487 (rank : 313)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	303	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

DC1L2_MOUSE
NC score	0.010484 (rank : 314)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	303	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PDL0	Gene names	Dync1li2, Dncli2, Dnclic2
Domain Architecture	No domain graphic available
Description	Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic).

B3A3_HUMAN
NC score	0.009960 (rank : 315)	θ value	2.36792 (rank : 168)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	20
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

FOXJ2_HUMAN
NC score	0.009729 (rank : 316)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	303	Target Neighborhood Hits	239	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

UBQL3_MOUSE
NC score	0.009668 (rank : 317)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	303	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

K0999_MOUSE
NC score	0.009638 (rank : 318)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	303	Target Neighborhood Hits	931	Shared Neighborhood Hits	39
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MORN1_HUMAN
NC score	0.009555 (rank : 319)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	303	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T089, Q8WW30, Q9H852	Gene names	MORN1
Domain Architecture	No domain graphic available
Description	MORN repeat-containing protein 1.

GAB1_MOUSE
NC score	0.009496 (rank : 320)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	303	Target Neighborhood Hits	233	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

MYO15_MOUSE
NC score	0.009473 (rank : 321)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	303	Target Neighborhood Hits	467	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SPAG1_MOUSE
NC score	0.009467 (rank : 322)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	303	Target Neighborhood Hits	218	Shared Neighborhood Hits	8
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SEM6B_HUMAN
NC score	0.009398 (rank : 323)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	303	Target Neighborhood Hits	187	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

TRIM8_MOUSE
NC score	0.009288 (rank : 324)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	303	Target Neighborhood Hits	674	Shared Neighborhood Hits	21
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

GAK_HUMAN
NC score	0.009243 (rank : 325)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	303	Target Neighborhood Hits	1028	Shared Neighborhood Hits	57
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HSF4_HUMAN
NC score	0.009022 (rank : 326)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	303	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

NFAC1_MOUSE
NC score	0.008983 (rank : 327)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	14
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SN1L1_HUMAN
NC score	0.008897 (rank : 328)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	303	Target Neighborhood Hits	911	Shared Neighborhood Hits	27
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

TSH1_HUMAN
NC score	0.008826 (rank : 329)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	303	Target Neighborhood Hits	558	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

S45A3_MOUSE
NC score	0.008745 (rank : 330)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	303	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0H7, Q8K252, Q8R1I0	Gene names	Slc45a3, Pcanap6, Prst
Domain Architecture	No domain graphic available
Description	Solute carrier family 45 member 3 (Prostate cancer-associated protein 6) (Prostein).

TSC1_HUMAN
NC score	0.008643 (rank : 331)	θ value	2.36792 (rank : 196)
Query Neighborhood Hits	303	Target Neighborhood Hits	765	Shared Neighborhood Hits	32
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

STK10_MOUSE
NC score	0.007974 (rank : 332)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	303	Target Neighborhood Hits	2132	Shared Neighborhood Hits	61
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LPIN3_HUMAN
NC score	0.007906 (rank : 333)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	303	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

DTNB_MOUSE
NC score	0.007827 (rank : 334)	θ value	2.36792 (rank : 176)
Query Neighborhood Hits	303	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

SORC3_HUMAN
NC score	0.007462 (rank : 335)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	303	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

PRGR_MOUSE
NC score	0.007352 (rank : 336)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	303	Target Neighborhood Hits	286	Shared Neighborhood Hits	34
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

HUNK_MOUSE
NC score	0.007176 (rank : 337)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	303	Target Neighborhood Hits	874	Shared Neighborhood Hits	25
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

TTLL5_MOUSE
NC score	0.007133 (rank : 338)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	303	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

HXB3_HUMAN
NC score	0.006996 (rank : 339)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	303	Target Neighborhood Hits	559	Shared Neighborhood Hits	37
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

ERBB2_HUMAN
NC score	0.006989 (rank : 340)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	303	Target Neighborhood Hits	1073	Shared Neighborhood Hits	44
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

TTLL4_MOUSE
NC score	0.006806 (rank : 341)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	303	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

PCOC1_HUMAN
NC score	0.006622 (rank : 342)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	303	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PAPPA_HUMAN
NC score	0.006587 (rank : 343)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	303	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

MK15_HUMAN
NC score	0.006559 (rank : 344)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	303	Target Neighborhood Hits	1038	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

ZN414_MOUSE
NC score	0.006213 (rank : 345)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	303	Target Neighborhood Hits	473	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DCK4, Q8CHU9	Gene names	Znf414, Zfp414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

M3K3_MOUSE
NC score	0.006176 (rank : 346)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	303	Target Neighborhood Hits	876	Shared Neighborhood Hits	26
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

NALP1_HUMAN
NC score	0.006133 (rank : 347)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	303	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

PUM2_MOUSE
NC score	0.006069 (rank : 348)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	303	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

ZHX3_HUMAN
NC score	0.005947 (rank : 349)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	303	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ABL1_HUMAN
NC score	0.005693 (rank : 350)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	303	Target Neighborhood Hits	1220	Shared Neighborhood Hits	66
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

WWP2_HUMAN
NC score	0.005199 (rank : 351)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	303	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

ADA12_MOUSE
NC score	0.004823 (rank : 352)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	303	Target Neighborhood Hits	474	Shared Neighborhood Hits	41
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

HXD3_HUMAN
NC score	0.004780 (rank : 353)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	303	Target Neighborhood Hits	433	Shared Neighborhood Hits	38
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MPIP2_MOUSE
NC score	0.004098 (rank : 354)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	303	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P30306, Q99LP3	Gene names	Cdc25b, Cdc25m2
Domain Architecture
Description	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B).

FGD5_HUMAN
NC score	0.003637 (rank : 355)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	303	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

MEFV_HUMAN
NC score	0.003589 (rank : 356)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	303	Target Neighborhood Hits	431	Shared Neighborhood Hits	26
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

GLI2_HUMAN
NC score	0.003487 (rank : 357)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	303	Target Neighborhood Hits	971	Shared Neighborhood Hits	57
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NOTC2_HUMAN
NC score	0.003261 (rank : 358)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	303	Target Neighborhood Hits	1113	Shared Neighborhood Hits	59
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RORG_HUMAN
NC score	0.002638 (rank : 359)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	303	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

SRC_MOUSE
NC score	0.001910 (rank : 360)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	303	Target Neighborhood Hits	1033	Shared Neighborhood Hits	26
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

MSX3_MOUSE
NC score	0.001259 (rank : 361)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	303	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P70354, P70246, Q03360, Q80W10	Gene names	Msx3, Msx-3
Domain Architecture
Description	Homeobox protein MSX-3.

SALL2_HUMAN
NC score	0.000969 (rank : 362)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	303	Target Neighborhood Hits	835	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y467, Q9Y4G1	Gene names	SALL2, KIAA0360, SAL2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Zinc finger protein SALL2) (HSal2).

HXD1_MOUSE
NC score	0.000894 (rank : 363)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	303	Target Neighborhood Hits	381	Shared Neighborhood Hits	12
SwissProt Accessions	Q01822	Gene names	Hoxd1, Hox-4.9, Hoxd-1
Domain Architecture
Description	Homeobox protein Hox-D1 (Hox-4.9).

RLF_HUMAN
NC score	0.000515 (rank : 364)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	303	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

TAAR1_HUMAN
NC score	0.000035 (rank : 365)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	303	Target Neighborhood Hits	906	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RJ0, Q3MIH8, Q5VUQ1	Gene names	TAAR1, TA1, TAR1, TRAR1
Domain Architecture
Description	Trace amine-associated receptor 1 (Trace amine receptor 1) (TaR-1).

MTR1L_HUMAN
NC score	-0.000734 (rank : 366)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	303	Target Neighborhood Hits	1180	Shared Neighborhood Hits	38
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

GLIS3_MOUSE
NC score	-0.000805 (rank : 367)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	303	Target Neighborhood Hits	861	Shared Neighborhood Hits	43
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

ZN236_HUMAN
NC score	-0.003213 (rank : 368)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	303	Target Neighborhood Hits	844	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZN746_HUMAN
NC score	-0.004890 (rank : 369)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	303	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.