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Network neighborhood for query Sequence : EPN3_MOUSE

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EPN3_MOUSE
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EPN3_HUMAN
θ value	0 (rank : 1)	NC score	0.934206 (rank : 2)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPN3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	312	Target Neighborhood Hits	312	Shared Neighborhood Hits	312
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPN1_MOUSE
θ value	4.6295e-105 (rank : 3)	NC score	0.862774 (rank : 5)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

EPN1_HUMAN
θ value	5.11853e-104 (rank : 4)	NC score	0.862215 (rank : 6)
Query Neighborhood Hits	312	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN2_MOUSE
θ value	4.19693e-98 (rank : 5)	NC score	0.883587 (rank : 3)
Query Neighborhood Hits	312	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

EPN2_HUMAN
θ value	1.22395e-89 (rank : 6)	NC score	0.879599 (rank : 4)
Query Neighborhood Hits	312	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

EPN4_HUMAN
θ value	2.58786e-39 (rank : 7)	NC score	0.779611 (rank : 7)
Query Neighborhood Hits	312	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

EPN4_MOUSE
θ value	2.58786e-39 (rank : 8)	NC score	0.777298 (rank : 8)
Query Neighborhood Hits	312	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

RPB1_HUMAN
θ value	4.1701e-05 (rank : 9)	NC score	0.147405 (rank : 24)
Query Neighborhood Hits	312	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	4.1701e-05 (rank : 10)	NC score	0.147614 (rank : 23)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	55
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

PELP1_MOUSE
θ value	7.1131e-05 (rank : 11)	NC score	0.119678 (rank : 47)
Query Neighborhood Hits	312	Target Neighborhood Hits	709	Shared Neighborhood Hits	112
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PRG4_HUMAN
θ value	9.29e-05 (rank : 12)	NC score	0.126009 (rank : 39)
Query Neighborhood Hits	312	Target Neighborhood Hits	764	Shared Neighborhood Hits	96
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GSCR1_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.155311 (rank : 20)
Query Neighborhood Hits	312	Target Neighborhood Hits	674	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

DAB2_MOUSE
θ value	0.00020696 (rank : 14)	NC score	0.085463 (rank : 95)
Query Neighborhood Hits	312	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

ENAH_MOUSE
θ value	0.000270298 (rank : 15)	NC score	0.108339 (rank : 62)
Query Neighborhood Hits	312	Target Neighborhood Hits	919	Shared Neighborhood Hits	100
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

AP180_HUMAN
θ value	0.000461057 (rank : 16)	NC score	0.123348 (rank : 41)
Query Neighborhood Hits	312	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

EP15R_MOUSE
θ value	0.000461057 (rank : 17)	NC score	0.060741 (rank : 182)
Query Neighborhood Hits	312	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

SYNJ1_MOUSE
θ value	0.00102713 (rank : 18)	NC score	0.112025 (rank : 57)
Query Neighborhood Hits	312	Target Neighborhood Hits	516	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

OBSCN_HUMAN
θ value	0.00134147 (rank : 19)	NC score	0.028409 (rank : 319)
Query Neighborhood Hits	312	Target Neighborhood Hits	1931	Shared Neighborhood Hits	130
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CS016_HUMAN
θ value	0.00175202 (rank : 20)	NC score	0.162536 (rank : 17)
Query Neighborhood Hits	312	Target Neighborhood Hits	310	Shared Neighborhood Hits	58
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

EP15R_HUMAN
θ value	0.00175202 (rank : 21)	NC score	0.055113 (rank : 219)
Query Neighborhood Hits	312	Target Neighborhood Hits	1083	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

MUC7_HUMAN
θ value	0.00175202 (rank : 22)	NC score	0.154678 (rank : 21)
Query Neighborhood Hits	312	Target Neighborhood Hits	538	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

CIC_MOUSE
θ value	0.00228821 (rank : 23)	NC score	0.125184 (rank : 40)
Query Neighborhood Hits	312	Target Neighborhood Hits	742	Shared Neighborhood Hits	139
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

K1802_HUMAN
θ value	0.00228821 (rank : 24)	NC score	0.137748 (rank : 35)
Query Neighborhood Hits	312	Target Neighborhood Hits	1378	Shared Neighborhood Hits	160
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BSN_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.170973 (rank : 13)
Query Neighborhood Hits	312	Target Neighborhood Hits	2057	Shared Neighborhood Hits	214
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

R51A1_MOUSE
θ value	0.00390308 (rank : 26)	NC score	0.079469 (rank : 108)
Query Neighborhood Hits	312	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RGS3_MOUSE
θ value	0.00390308 (rank : 27)	NC score	0.146355 (rank : 25)
Query Neighborhood Hits	312	Target Neighborhood Hits	1621	Shared Neighborhood Hits	225
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

K0329_HUMAN
θ value	0.00509761 (rank : 28)	NC score	0.096799 (rank : 78)
Query Neighborhood Hits	312	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

SYNJ1_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.103569 (rank : 67)
Query Neighborhood Hits	312	Target Neighborhood Hits	498	Shared Neighborhood Hits	93
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

AP180_MOUSE
θ value	0.00665767 (rank : 30)	NC score	0.146274 (rank : 26)
Query Neighborhood Hits	312	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

MLL2_HUMAN
θ value	0.00665767 (rank : 31)	NC score	0.109221 (rank : 60)
Query Neighborhood Hits	312	Target Neighborhood Hits	1788	Shared Neighborhood Hits	162
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MUC2_HUMAN
θ value	0.00665767 (rank : 32)	NC score	0.086196 (rank : 94)
Query Neighborhood Hits	312	Target Neighborhood Hits	906	Shared Neighborhood Hits	93
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SYN3_MOUSE
θ value	0.00869519 (rank : 33)	NC score	0.064717 (rank : 164)
Query Neighborhood Hits	312	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

CIC_HUMAN
θ value	0.0113563 (rank : 34)	NC score	0.137823 (rank : 34)
Query Neighborhood Hits	312	Target Neighborhood Hits	992	Shared Neighborhood Hits	168
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CN032_MOUSE
θ value	0.0113563 (rank : 35)	NC score	0.164457 (rank : 16)
Query Neighborhood Hits	312	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

ESX1L_HUMAN
θ value	0.0113563 (rank : 36)	NC score	0.027727 (rank : 320)
Query Neighborhood Hits	312	Target Neighborhood Hits	498	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

NU214_HUMAN
θ value	0.0113563 (rank : 37)	NC score	0.140476 (rank : 32)
Query Neighborhood Hits	312	Target Neighborhood Hits	657	Shared Neighborhood Hits	90
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

FOXM1_HUMAN
θ value	0.0148317 (rank : 38)	NC score	0.039379 (rank : 281)
Query Neighborhood Hits	312	Target Neighborhood Hits	167	Shared Neighborhood Hits	28
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

PCLO_HUMAN
θ value	0.0193708 (rank : 39)	NC score	0.122929 (rank : 42)
Query Neighborhood Hits	312	Target Neighborhood Hits	2046	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FOSB_HUMAN
θ value	0.0252991 (rank : 40)	NC score	0.076963 (rank : 115)
Query Neighborhood Hits	312	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

HCN4_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.055677 (rank : 215)
Query Neighborhood Hits	312	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

NFAC4_HUMAN
θ value	0.0252991 (rank : 42)	NC score	0.057699 (rank : 197)
Query Neighborhood Hits	312	Target Neighborhood Hits	165	Shared Neighborhood Hits	27
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PHLPP_HUMAN
θ value	0.0252991 (rank : 43)	NC score	0.032070 (rank : 308)
Query Neighborhood Hits	312	Target Neighborhood Hits	604	Shared Neighborhood Hits	60
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SALL3_HUMAN
θ value	0.0252991 (rank : 44)	NC score	0.023272 (rank : 338)
Query Neighborhood Hits	312	Target Neighborhood Hits	1066	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

K1802_MOUSE
θ value	0.0330416 (rank : 45)	NC score	0.151227 (rank : 22)
Query Neighborhood Hits	312	Target Neighborhood Hits	1596	Shared Neighborhood Hits	185
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ARI1B_HUMAN
θ value	0.0563607 (rank : 46)	NC score	0.088977 (rank : 89)
Query Neighborhood Hits	312	Target Neighborhood Hits	567	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CN032_HUMAN
θ value	0.0563607 (rank : 47)	NC score	0.176834 (rank : 12)
Query Neighborhood Hits	312	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

MLL3_MOUSE
θ value	0.0563607 (rank : 48)	NC score	0.141629 (rank : 30)
Query Neighborhood Hits	312	Target Neighborhood Hits	1399	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SHAN1_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.057510 (rank : 199)
Query Neighborhood Hits	312	Target Neighborhood Hits	1041	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ALEX_MOUSE
θ value	0.0736092 (rank : 50)	NC score	0.098980 (rank : 74)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PO121_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.102675 (rank : 69)
Query Neighborhood Hits	312	Target Neighborhood Hits	345	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PTN23_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.047302 (rank : 258)
Query Neighborhood Hits	312	Target Neighborhood Hits	646	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

CSKI2_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.041825 (rank : 273)
Query Neighborhood Hits	312	Target Neighborhood Hits	747	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PAK7_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.010820 (rank : 398)
Query Neighborhood Hits	312	Target Neighborhood Hits	875	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

RERE_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.093095 (rank : 86)
Query Neighborhood Hits	312	Target Neighborhood Hits	785	Shared Neighborhood Hits	96
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RREB1_HUMAN
θ value	0.0961366 (rank : 56)	NC score	0.015635 (rank : 369)
Query Neighborhood Hits	312	Target Neighborhood Hits	879	Shared Neighborhood Hits	49
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SF01_MOUSE
θ value	0.0961366 (rank : 57)	NC score	0.078306 (rank : 110)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SRRM2_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.096942 (rank : 77)
Query Neighborhood Hits	312	Target Neighborhood Hits	1296	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TAF4_HUMAN
θ value	0.0961366 (rank : 59)	NC score	0.127405 (rank : 38)
Query Neighborhood Hits	312	Target Neighborhood Hits	687	Shared Neighborhood Hits	94
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

USH1C_MOUSE
θ value	0.0961366 (rank : 60)	NC score	0.034671 (rank : 302)
Query Neighborhood Hits	312	Target Neighborhood Hits	557	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

WNK2_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.031812 (rank : 309)
Query Neighborhood Hits	312	Target Neighborhood Hits	1407	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BAT2_HUMAN
θ value	0.125558 (rank : 62)	NC score	0.121582 (rank : 44)
Query Neighborhood Hits	312	Target Neighborhood Hits	931	Shared Neighborhood Hits	139
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CABIN_HUMAN
θ value	0.125558 (rank : 63)	NC score	0.108845 (rank : 61)
Query Neighborhood Hits	312	Target Neighborhood Hits	490	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

DYN1_HUMAN
θ value	0.125558 (rank : 64)	NC score	0.055815 (rank : 212)
Query Neighborhood Hits	312	Target Neighborhood Hits	216	Shared Neighborhood Hits	47
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

FOSB_MOUSE
θ value	0.125558 (rank : 65)	NC score	0.075838 (rank : 121)
Query Neighborhood Hits	312	Target Neighborhood Hits	137	Shared Neighborhood Hits	14
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

IF4G1_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.062410 (rank : 170)
Query Neighborhood Hits	312	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ACK1_MOUSE
θ value	0.163984 (rank : 67)	NC score	0.016239 (rank : 366)
Query Neighborhood Hits	312	Target Neighborhood Hits	1080	Shared Neighborhood Hits	83
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

BAT2_MOUSE
θ value	0.163984 (rank : 68)	NC score	0.115842 (rank : 50)
Query Neighborhood Hits	312	Target Neighborhood Hits	947	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

K0310_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.095435 (rank : 81)
Query Neighborhood Hits	312	Target Neighborhood Hits	420	Shared Neighborhood Hits	88
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MUCDL_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.056275 (rank : 210)
Query Neighborhood Hits	312	Target Neighborhood Hits	461	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

S23IP_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.071215 (rank : 139)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	79
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

WWP1_MOUSE
θ value	0.163984 (rank : 72)	NC score	0.013909 (rank : 381)
Query Neighborhood Hits	312	Target Neighborhood Hits	138	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

PO121_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.094184 (rank : 83)
Query Neighborhood Hits	312	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SKIV2_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.032846 (rank : 305)
Query Neighborhood Hits	312	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

3BP1_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.046216 (rank : 260)
Query Neighborhood Hits	312	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CJ026_MOUSE
θ value	0.279714 (rank : 76)	NC score	0.048426 (rank : 256)
Query Neighborhood Hits	312	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

CSPG3_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.043740 (rank : 269)
Query Neighborhood Hits	312	Target Neighborhood Hits	676	Shared Neighborhood Hits	66
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HRBL_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.093709 (rank : 85)
Query Neighborhood Hits	312	Target Neighborhood Hits	179	Shared Neighborhood Hits	45
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MDC1_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.155316 (rank : 19)
Query Neighborhood Hits	312	Target Neighborhood Hits	998	Shared Neighborhood Hits	146
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

SAPS2_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.033041 (rank : 304)
Query Neighborhood Hits	312	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

T22D2_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.079138 (rank : 109)
Query Neighborhood Hits	312	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TB182_HUMAN
θ value	0.279714 (rank : 82)	NC score	0.074595 (rank : 129)
Query Neighborhood Hits	312	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

ZN541_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.051563 (rank : 245)
Query Neighborhood Hits	312	Target Neighborhood Hits	203	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

HCN4_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.050279 (rank : 253)
Query Neighborhood Hits	312	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MISS_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.166065 (rank : 14)
Query Neighborhood Hits	312	Target Neighborhood Hits	444	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

MLL4_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.067642 (rank : 154)
Query Neighborhood Hits	312	Target Neighborhood Hits	722	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NACAM_MOUSE
θ value	0.365318 (rank : 87)	NC score	0.187286 (rank : 10)
Query Neighborhood Hits	312	Target Neighborhood Hits	1866	Shared Neighborhood Hits	214
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PCQAP_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.077833 (rank : 113)
Query Neighborhood Hits	312	Target Neighborhood Hits	549	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

SOX18_HUMAN
θ value	0.365318 (rank : 89)	NC score	0.025088 (rank : 331)
Query Neighborhood Hits	312	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

TCGAP_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.108142 (rank : 63)
Query Neighborhood Hits	312	Target Neighborhood Hits	872	Shared Neighborhood Hits	141
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TGON2_HUMAN
θ value	0.365318 (rank : 91)	NC score	0.084958 (rank : 98)
Query Neighborhood Hits	312	Target Neighborhood Hits	1037	Shared Neighborhood Hits	108
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ARI1A_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.112918 (rank : 54)
Query Neighborhood Hits	312	Target Neighborhood Hits	787	Shared Neighborhood Hits	124
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CA106_HUMAN
θ value	0.47712 (rank : 93)	NC score	0.039453 (rank : 280)
Query Neighborhood Hits	312	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

DYN1_MOUSE
θ value	0.47712 (rank : 94)	NC score	0.051942 (rank : 242)
Query Neighborhood Hits	312	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

GGA3_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.031082 (rank : 312)
Query Neighborhood Hits	312	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HDAC4_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.025965 (rank : 328)
Query Neighborhood Hits	312	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

IRAK1_MOUSE
θ value	0.47712 (rank : 97)	NC score	0.013474 (rank : 383)
Query Neighborhood Hits	312	Target Neighborhood Hits	784	Shared Neighborhood Hits	26
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

JPH4_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.024577 (rank : 334)
Query Neighborhood Hits	312	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

MAP1A_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.071313 (rank : 138)
Query Neighborhood Hits	312	Target Neighborhood Hits	1626	Shared Neighborhood Hits	148
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NCOA6_HUMAN
θ value	0.47712 (rank : 100)	NC score	0.164979 (rank : 15)
Query Neighborhood Hits	312	Target Neighborhood Hits	1202	Shared Neighborhood Hits	195
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NOLC1_HUMAN
θ value	0.47712 (rank : 101)	NC score	0.056720 (rank : 206)
Query Neighborhood Hits	312	Target Neighborhood Hits	452	Shared Neighborhood Hits	38
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PAK7_MOUSE
θ value	0.47712 (rank : 102)	NC score	0.009106 (rank : 404)
Query Neighborhood Hits	312	Target Neighborhood Hits	875	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PGCA_MOUSE
θ value	0.47712 (rank : 103)	NC score	0.038213 (rank : 286)
Query Neighborhood Hits	312	Target Neighborhood Hits	643	Shared Neighborhood Hits	49
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SSBP4_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.121619 (rank : 43)
Query Neighborhood Hits	312	Target Neighborhood Hits	753	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

YLPM1_MOUSE
θ value	0.47712 (rank : 105)	NC score	0.077269 (rank : 114)
Query Neighborhood Hits	312	Target Neighborhood Hits	505	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

BAIP2_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.023222 (rank : 340)
Query Neighborhood Hits	312	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

BCL9_MOUSE
θ value	0.62314 (rank : 107)	NC score	0.114740 (rank : 52)
Query Neighborhood Hits	312	Target Neighborhood Hits	770	Shared Neighborhood Hits	154
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BSN_HUMAN
θ value	0.62314 (rank : 108)	NC score	0.119228 (rank : 48)
Query Neighborhood Hits	312	Target Neighborhood Hits	1537	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

EP15_MOUSE
θ value	0.62314 (rank : 109)	NC score	0.037285 (rank : 289)
Query Neighborhood Hits	312	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

PI5PA_HUMAN
θ value	0.62314 (rank : 110)	NC score	0.144770 (rank : 28)
Query Neighborhood Hits	312	Target Neighborhood Hits	749	Shared Neighborhood Hits	157
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SF01_HUMAN
θ value	0.62314 (rank : 111)	NC score	0.075010 (rank : 127)
Query Neighborhood Hits	312	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SFPQ_MOUSE
θ value	0.62314 (rank : 112)	NC score	0.055696 (rank : 213)
Query Neighborhood Hits	312	Target Neighborhood Hits	958	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SMCA4_HUMAN
θ value	0.62314 (rank : 113)	NC score	0.037470 (rank : 288)
Query Neighborhood Hits	312	Target Neighborhood Hits	597	Shared Neighborhood Hits	75
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TCOF_MOUSE
θ value	0.62314 (rank : 114)	NC score	0.075741 (rank : 122)
Query Neighborhood Hits	312	Target Neighborhood Hits	471	Shared Neighborhood Hits	58
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

AMOL1_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.020652 (rank : 346)
Query Neighborhood Hits	312	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

MILK2_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.036853 (rank : 292)
Query Neighborhood Hits	312	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MK07_MOUSE
θ value	0.813845 (rank : 117)	NC score	0.012052 (rank : 396)
Query Neighborhood Hits	312	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MYCN_HUMAN
θ value	0.813845 (rank : 118)	NC score	0.027184 (rank : 321)
Query Neighborhood Hits	312	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

PGCA_HUMAN
θ value	0.813845 (rank : 119)	NC score	0.052766 (rank : 237)
Query Neighborhood Hits	312	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PSL1_HUMAN
θ value	0.813845 (rank : 120)	NC score	0.113065 (rank : 53)
Query Neighborhood Hits	312	Target Neighborhood Hits	650	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RERE_HUMAN
θ value	0.813845 (rank : 121)	NC score	0.087270 (rank : 92)
Query Neighborhood Hits	312	Target Neighborhood Hits	779	Shared Neighborhood Hits	94
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ZN750_MOUSE
θ value	0.813845 (rank : 122)	NC score	0.101210 (rank : 72)
Query Neighborhood Hits	312	Target Neighborhood Hits	346	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

ANK2_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.052999 (rank : 235)
Query Neighborhood Hits	312	Target Neighborhood Hits	1615	Shared Neighborhood Hits	158
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CNOT3_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.068937 (rank : 151)
Query Neighborhood Hits	312	Target Neighborhood Hits	425	Shared Neighborhood Hits	55
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO3A1_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.040085 (rank : 277)
Query Neighborhood Hits	312	Target Neighborhood Hits	466	Shared Neighborhood Hits	69
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

DYN3_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.039254 (rank : 282)
Query Neighborhood Hits	312	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

FMNL_HUMAN
θ value	1.06291 (rank : 127)	NC score	0.050019 (rank : 255)
Query Neighborhood Hits	312	Target Neighborhood Hits	529	Shared Neighborhood Hits	65
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GGN_MOUSE
θ value	1.06291 (rank : 128)	NC score	0.078235 (rank : 111)
Query Neighborhood Hits	312	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

JPH2_HUMAN
θ value	1.06291 (rank : 129)	NC score	0.071477 (rank : 136)
Query Neighborhood Hits	312	Target Neighborhood Hits	639	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NFH_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.103291 (rank : 68)
Query Neighborhood Hits	312	Target Neighborhood Hits	2247	Shared Neighborhood Hits	208
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCLO_MOUSE
θ value	1.06291 (rank : 131)	NC score	0.120711 (rank : 45)
Query Neighborhood Hits	312	Target Neighborhood Hits	2275	Shared Neighborhood Hits	214
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRG4_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.080838 (rank : 106)
Query Neighborhood Hits	312	Target Neighborhood Hits	624	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PS1C2_HUMAN
θ value	1.06291 (rank : 133)	NC score	0.116341 (rank : 49)
Query Neighborhood Hits	312	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PS1C2_MOUSE
θ value	1.06291 (rank : 134)	NC score	0.120556 (rank : 46)
Query Neighborhood Hits	312	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

SYNPO_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.060695 (rank : 183)
Query Neighborhood Hits	312	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TNC6B_HUMAN
θ value	1.06291 (rank : 136)	NC score	0.047763 (rank : 257)
Query Neighborhood Hits	312	Target Neighborhood Hits	256	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

ATF7_MOUSE
θ value	1.38821 (rank : 137)	NC score	0.031080 (rank : 313)
Query Neighborhood Hits	312	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BPAEA_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.009669 (rank : 403)
Query Neighborhood Hits	312	Target Neighborhood Hits	1480	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CG1_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.075214 (rank : 126)
Query Neighborhood Hits	312	Target Neighborhood Hits	222	Shared Neighborhood Hits	58
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CO9A3_HUMAN
θ value	1.38821 (rank : 140)	NC score	0.025788 (rank : 329)
Query Neighborhood Hits	312	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

CUTL2_HUMAN
θ value	1.38821 (rank : 141)	NC score	0.039814 (rank : 278)
Query Neighborhood Hits	312	Target Neighborhood Hits	906	Shared Neighborhood Hits	68
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

DEN1A_MOUSE
θ value	1.38821 (rank : 142)	NC score	0.044861 (rank : 263)
Query Neighborhood Hits	312	Target Neighborhood Hits	178	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DIAP1_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.035619 (rank : 298)
Query Neighborhood Hits	312	Target Neighborhood Hits	839	Shared Neighborhood Hits	60
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FOXD2_MOUSE
θ value	1.38821 (rank : 144)	NC score	0.014831 (rank : 372)
Query Neighborhood Hits	312	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

MAGC1_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.038965 (rank : 283)
Query Neighborhood Hits	312	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MTF1_HUMAN
θ value	1.38821 (rank : 146)	NC score	0.002095 (rank : 420)
Query Neighborhood Hits	312	Target Neighborhood Hits	814	Shared Neighborhood Hits	37
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MYO15_MOUSE
θ value	1.38821 (rank : 147)	NC score	0.026695 (rank : 322)
Query Neighborhood Hits	312	Target Neighborhood Hits	467	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NCOR2_HUMAN
θ value	1.38821 (rank : 148)	NC score	0.069826 (rank : 147)
Query Neighborhood Hits	312	Target Neighborhood Hits	870	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NIPA_HUMAN
θ value	1.38821 (rank : 149)	NC score	0.039664 (rank : 279)
Query Neighborhood Hits	312	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

PAR10_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.026081 (rank : 326)
Query Neighborhood Hits	312	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

PHAR2_HUMAN
θ value	1.38821 (rank : 151)	NC score	0.036722 (rank : 293)
Query Neighborhood Hits	312	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

SAPS1_MOUSE
θ value	1.38821 (rank : 152)	NC score	0.040699 (rank : 275)
Query Neighborhood Hits	312	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SON_MOUSE
θ value	1.38821 (rank : 153)	NC score	0.109546 (rank : 59)
Query Neighborhood Hits	312	Target Neighborhood Hits	957	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SRRM2_MOUSE
θ value	1.38821 (rank : 154)	NC score	0.114960 (rank : 51)
Query Neighborhood Hits	312	Target Neighborhood Hits	1470	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATX2_HUMAN
θ value	1.81305 (rank : 155)	NC score	0.047253 (rank : 259)
Query Neighborhood Hits	312	Target Neighborhood Hits	375	Shared Neighborhood Hits	59
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ATX7_MOUSE
θ value	1.81305 (rank : 156)	NC score	0.060597 (rank : 185)
Query Neighborhood Hits	312	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BRD8_MOUSE
θ value	1.81305 (rank : 157)	NC score	0.042751 (rank : 272)
Query Neighborhood Hits	312	Target Neighborhood Hits	422	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CF047_MOUSE
θ value	1.81305 (rank : 158)	NC score	0.026672 (rank : 323)
Query Neighborhood Hits	312	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

CNOT3_MOUSE
θ value	1.81305 (rank : 159)	NC score	0.065678 (rank : 160)
Query Neighborhood Hits	312	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO1A1_HUMAN
θ value	1.81305 (rank : 160)	NC score	0.037603 (rank : 287)
Query Neighborhood Hits	312	Target Neighborhood Hits	475	Shared Neighborhood Hits	67
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CTGE6_HUMAN
θ value	1.81305 (rank : 161)	NC score	0.019817 (rank : 349)
Query Neighborhood Hits	312	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

EMID2_MOUSE
θ value	1.81305 (rank : 162)	NC score	0.036268 (rank : 295)
Query Neighborhood Hits	312	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

FBXL5_HUMAN
θ value	1.81305 (rank : 163)	NC score	0.026589 (rank : 324)
Query Neighborhood Hits	312	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

GCNL2_HUMAN
θ value	1.81305 (rank : 164)	NC score	0.026302 (rank : 325)
Query Neighborhood Hits	312	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GNAS1_HUMAN
θ value	1.81305 (rank : 165)	NC score	0.019702 (rank : 350)
Query Neighborhood Hits	312	Target Neighborhood Hits	278	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

MAST3_HUMAN
θ value	1.81305 (rank : 166)	NC score	0.008580 (rank : 406)
Query Neighborhood Hits	312	Target Neighborhood Hits	1128	Shared Neighborhood Hits	58
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MBD6_HUMAN
θ value	1.81305 (rank : 167)	NC score	0.090864 (rank : 88)
Query Neighborhood Hits	312	Target Neighborhood Hits	349	Shared Neighborhood Hits	69
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MEF2B_HUMAN
θ value	1.81305 (rank : 168)	NC score	0.044020 (rank : 268)
Query Neighborhood Hits	312	Target Neighborhood Hits	150	Shared Neighborhood Hits	41
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

MILK1_MOUSE
θ value	1.81305 (rank : 169)	NC score	0.070735 (rank : 143)
Query Neighborhood Hits	312	Target Neighborhood Hits	788	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PI5PA_MOUSE
θ value	1.81305 (rank : 170)	NC score	0.081905 (rank : 104)
Query Neighborhood Hits	312	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PME17_MOUSE
θ value	1.81305 (rank : 171)	NC score	0.020642 (rank : 347)
Query Neighborhood Hits	312	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

TAD3L_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.035231 (rank : 300)
Query Neighborhood Hits	312	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	1.81305 (rank : 173)	NC score	0.035367 (rank : 299)
Query Neighborhood Hits	312	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TTC15_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.037045 (rank : 290)
Query Neighborhood Hits	312	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

UBQL4_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.024060 (rank : 336)
Query Neighborhood Hits	312	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

UBQL4_MOUSE
θ value	1.81305 (rank : 176)	NC score	0.024909 (rank : 332)
Query Neighborhood Hits	312	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

WHRN_MOUSE
θ value	1.81305 (rank : 177)	NC score	0.029392 (rank : 317)
Query Neighborhood Hits	312	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CS007_MOUSE
θ value	2.36792 (rank : 178)	NC score	0.062324 (rank : 172)
Query Neighborhood Hits	312	Target Neighborhood Hits	464	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DVL2_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.017380 (rank : 359)
Query Neighborhood Hits	312	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EMIL2_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.029446 (rank : 316)
Query Neighborhood Hits	312	Target Neighborhood Hits	573	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EP300_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.088295 (rank : 90)
Query Neighborhood Hits	312	Target Neighborhood Hits	821	Shared Neighborhood Hits	118
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GATA5_HUMAN
θ value	2.36792 (rank : 182)	NC score	0.014863 (rank : 371)
Query Neighborhood Hits	312	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

GP152_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.030614 (rank : 314)
Query Neighborhood Hits	312	Target Neighborhood Hits	636	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

LEUK_MOUSE
θ value	2.36792 (rank : 184)	NC score	0.060959 (rank : 179)
Query Neighborhood Hits	312	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

MYRIP_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.016892 (rank : 361)
Query Neighborhood Hits	312	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NSD1_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.044722 (rank : 265)
Query Neighborhood Hits	312	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PIBF1_HUMAN
θ value	2.36792 (rank : 187)	NC score	0.012245 (rank : 392)
Query Neighborhood Hits	312	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PRRT3_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.058752 (rank : 193)
Query Neighborhood Hits	312	Target Neighborhood Hits	162	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PTPRN_MOUSE
θ value	2.36792 (rank : 189)	NC score	0.017628 (rank : 358)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	39
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SYN1_HUMAN
θ value	2.36792 (rank : 190)	NC score	0.068779 (rank : 152)
Query Neighborhood Hits	312	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TACC2_MOUSE
θ value	2.36792 (rank : 191)	NC score	0.044703 (rank : 266)
Query Neighborhood Hits	312	Target Neighborhood Hits	774	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WBP11_HUMAN
θ value	2.36792 (rank : 192)	NC score	0.079950 (rank : 107)
Query Neighborhood Hits	312	Target Neighborhood Hits	354	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

ADEC1_MOUSE
θ value	3.0926 (rank : 193)	NC score	0.004854 (rank : 416)
Query Neighborhood Hits	312	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

AFF1_MOUSE
θ value	3.0926 (rank : 194)	NC score	0.035925 (rank : 297)
Query Neighborhood Hits	312	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CAC1H_HUMAN
θ value	3.0926 (rank : 195)	NC score	0.016445 (rank : 365)
Query Neighborhood Hits	312	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CHFR_HUMAN
θ value	3.0926 (rank : 196)	NC score	0.010455 (rank : 400)
Query Neighborhood Hits	312	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

DIDO1_HUMAN
θ value	3.0926 (rank : 197)	NC score	0.102369 (rank : 71)
Query Neighborhood Hits	312	Target Neighborhood Hits	960	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MBB1A_HUMAN
θ value	3.0926 (rank : 198)	NC score	0.072170 (rank : 133)
Query Neighborhood Hits	312	Target Neighborhood Hits	665	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MEGF9_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.018222 (rank : 356)
Query Neighborhood Hits	312	Target Neighborhood Hits	557	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PP16A_MOUSE
θ value	3.0926 (rank : 200)	NC score	0.009689 (rank : 402)
Query Neighborhood Hits	312	Target Neighborhood Hits	318	Shared Neighborhood Hits	10
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

PRR12_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.092505 (rank : 87)
Query Neighborhood Hits	312	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

R3HD2_MOUSE
θ value	3.0926 (rank : 202)	NC score	0.070021 (rank : 146)
Query Neighborhood Hits	312	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RGS7_HUMAN
θ value	3.0926 (rank : 203)	NC score	0.015397 (rank : 370)
Query Neighborhood Hits	312	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

RTN4_MOUSE
θ value	3.0926 (rank : 204)	NC score	0.045656 (rank : 262)
Query Neighborhood Hits	312	Target Neighborhood Hits	341	Shared Neighborhood Hits	47
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

SC24C_HUMAN
θ value	3.0926 (rank : 205)	NC score	0.110570 (rank : 58)
Query Neighborhood Hits	312	Target Neighborhood Hits	662	Shared Neighborhood Hits	135
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SYAP1_HUMAN
θ value	3.0926 (rank : 206)	NC score	0.019653 (rank : 351)
Query Neighborhood Hits	312	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

ZFP28_HUMAN
θ value	3.0926 (rank : 207)	NC score	-0.001903 (rank : 428)
Query Neighborhood Hits	312	Target Neighborhood Hits	843	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ACK1_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.014712 (rank : 375)
Query Neighborhood Hits	312	Target Neighborhood Hits	1140	Shared Neighborhood Hits	91
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ATF7_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.031173 (rank : 311)
Query Neighborhood Hits	312	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

ATX3_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.044723 (rank : 264)
Query Neighborhood Hits	312	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

BRSK1_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.005083 (rank : 415)
Query Neighborhood Hits	312	Target Neighborhood Hits	942	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CBP_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.094145 (rank : 84)
Query Neighborhood Hits	312	Target Neighborhood Hits	941	Shared Neighborhood Hits	144
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	4.03905 (rank : 213)	NC score	0.099653 (rank : 73)
Query Neighborhood Hits	312	Target Neighborhood Hits	1051	Shared Neighborhood Hits	147
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CSKI1_HUMAN
θ value	4.03905 (rank : 214)	NC score	0.041187 (rank : 274)
Query Neighborhood Hits	312	Target Neighborhood Hits	997	Shared Neighborhood Hits	121
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DSPP_MOUSE
θ value	4.03905 (rank : 215)	NC score	0.023006 (rank : 342)
Query Neighborhood Hits	312	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HIC1_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.000647 (rank : 424)
Query Neighborhood Hits	312	Target Neighborhood Hits	838	Shared Neighborhood Hits	30
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

IRAK1_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.016468 (rank : 364)
Query Neighborhood Hits	312	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRX3_HUMAN
θ value	4.03905 (rank : 218)	NC score	0.019516 (rank : 353)
Query Neighborhood Hits	312	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

IRX3_MOUSE
θ value	4.03905 (rank : 219)	NC score	0.017068 (rank : 360)
Query Neighborhood Hits	312	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ITSN1_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.032259 (rank : 307)
Query Neighborhood Hits	312	Target Neighborhood Hits	1757	Shared Neighborhood Hits	90
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MINT_HUMAN
θ value	4.03905 (rank : 221)	NC score	0.051314 (rank : 248)
Query Neighborhood Hits	312	Target Neighborhood Hits	1291	Shared Neighborhood Hits	120
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MNAB_MOUSE
θ value	4.03905 (rank : 222)	NC score	0.015735 (rank : 368)
Query Neighborhood Hits	312	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MUC1_HUMAN
θ value	4.03905 (rank : 223)	NC score	0.191093 (rank : 9)
Query Neighborhood Hits	312	Target Neighborhood Hits	975	Shared Neighborhood Hits	172
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NEST_HUMAN
θ value	4.03905 (rank : 224)	NC score	0.023040 (rank : 341)
Query Neighborhood Hits	312	Target Neighborhood Hits	1305	Shared Neighborhood Hits	69
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NKX61_MOUSE
θ value	4.03905 (rank : 225)	NC score	0.012475 (rank : 391)
Query Neighborhood Hits	312	Target Neighborhood Hits	439	Shared Neighborhood Hits	29
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

RTN1_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.033334 (rank : 303)
Query Neighborhood Hits	312	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

RUSC2_HUMAN
θ value	4.03905 (rank : 227)	NC score	0.023410 (rank : 337)
Query Neighborhood Hits	312	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SOCS7_MOUSE
θ value	4.03905 (rank : 228)	NC score	0.014348 (rank : 380)
Query Neighborhood Hits	312	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

WBP11_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.076779 (rank : 116)
Query Neighborhood Hits	312	Target Neighborhood Hits	362	Shared Neighborhood Hits	60
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WFS1_HUMAN
θ value	4.03905 (rank : 230)	NC score	0.014783 (rank : 373)
Query Neighborhood Hits	312	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

ZN414_HUMAN
θ value	4.03905 (rank : 231)	NC score	0.023239 (rank : 339)
Query Neighborhood Hits	312	Target Neighborhood Hits	548	Shared Neighborhood Hits	35
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

AP2A1_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.011421 (rank : 397)
Query Neighborhood Hits	312	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

ATN1_HUMAN
θ value	5.27518 (rank : 233)	NC score	0.103661 (rank : 66)
Query Neighborhood Hits	312	Target Neighborhood Hits	676	Shared Neighborhood Hits	95
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BIRC7_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.007009 (rank : 412)
Query Neighborhood Hits	312	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CO1A1_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.036209 (rank : 296)
Query Neighborhood Hits	312	Target Neighborhood Hits	457	Shared Neighborhood Hits	65
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO1A2_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.036882 (rank : 291)
Query Neighborhood Hits	312	Target Neighborhood Hits	329	Shared Neighborhood Hits	56
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CS007_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.057651 (rank : 198)
Query Neighborhood Hits	312	Target Neighborhood Hits	401	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

CSKI1_MOUSE
θ value	5.27518 (rank : 238)	NC score	0.045838 (rank : 261)
Query Neighborhood Hits	312	Target Neighborhood Hits	1031	Shared Neighborhood Hits	129
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HLAH_HUMAN
θ value	5.27518 (rank : 239)	NC score	-0.001394 (rank : 427)
Query Neighborhood Hits	312	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	P01893	Gene names	HLA-H, HLAH
Domain Architecture
Description	HLA class I histocompatibility antigen, alpha chain H precursor (HLA- AR) (HLA-12.4).

JIP2_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.028448 (rank : 318)
Query Neighborhood Hits	312	Target Neighborhood Hits	288	Shared Neighborhood Hits	49
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KLF17_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.012848 (rank : 388)
Query Neighborhood Hits	312	Target Neighborhood Hits	882	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

M3K11_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.007968 (rank : 410)
Query Neighborhood Hits	312	Target Neighborhood Hits	1136	Shared Neighborhood Hits	53
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PCX3_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.030243 (rank : 315)
Query Neighborhood Hits	312	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

PGBM_MOUSE
θ value	5.27518 (rank : 244)	NC score	0.002480 (rank : 419)
Query Neighborhood Hits	312	Target Neighborhood Hits	1073	Shared Neighborhood Hits	19
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PLXB1_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.014735 (rank : 374)
Query Neighborhood Hits	312	Target Neighborhood Hits	259	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

RAPH1_HUMAN
θ value	5.27518 (rank : 246)	NC score	0.063859 (rank : 168)
Query Neighborhood Hits	312	Target Neighborhood Hits	593	Shared Neighborhood Hits	90
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RGL2_MOUSE
θ value	5.27518 (rank : 247)	NC score	0.008188 (rank : 409)
Query Neighborhood Hits	312	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RTN1_MOUSE
θ value	5.27518 (rank : 248)	NC score	0.031464 (rank : 310)
Query Neighborhood Hits	312	Target Neighborhood Hits	189	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

ZBP1_HUMAN
θ value	5.27518 (rank : 249)	NC score	0.032586 (rank : 306)
Query Neighborhood Hits	312	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H171, Q5JY39, Q9BYW4	Gene names	ZBP1, C20orf183, DLM1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

AF17_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.020985 (rank : 344)
Query Neighborhood Hits	312	Target Neighborhood Hits	230	Shared Neighborhood Hits	35
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

BORG5_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.050286 (rank : 252)
Query Neighborhood Hits	312	Target Neighborhood Hits	135	Shared Neighborhood Hits	30
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

CENG1_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.012073 (rank : 395)
Query Neighborhood Hits	312	Target Neighborhood Hits	544	Shared Neighborhood Hits	39
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CUTL1_MOUSE
θ value	6.88961 (rank : 253)	NC score	0.038282 (rank : 285)
Query Neighborhood Hits	312	Target Neighborhood Hits	1620	Shared Neighborhood Hits	109
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL2_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.026053 (rank : 327)
Query Neighborhood Hits	312	Target Neighborhood Hits	771	Shared Neighborhood Hits	52
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EMID2_HUMAN
θ value	6.88961 (rank : 255)	NC score	0.036610 (rank : 294)
Query Neighborhood Hits	312	Target Neighborhood Hits	226	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

FETUB_MOUSE
θ value	6.88961 (rank : 256)	NC score	0.015929 (rank : 367)
Query Neighborhood Hits	312	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

GATA5_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.012692 (rank : 390)
Query Neighborhood Hits	312	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

MAGE1_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.137459 (rank : 36)
Query Neighborhood Hits	312	Target Neighborhood Hits	1389	Shared Neighborhood Hits	204
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MTF1_MOUSE
θ value	6.88961 (rank : 259)	NC score	0.001071 (rank : 423)
Query Neighborhood Hits	312	Target Neighborhood Hits	785	Shared Neighborhood Hits	29
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NELFA_MOUSE
θ value	6.88961 (rank : 260)	NC score	0.040500 (rank : 276)
Query Neighborhood Hits	312	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NF2L3_MOUSE
θ value	6.88961 (rank : 261)	NC score	0.014664 (rank : 376)
Query Neighborhood Hits	312	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NFIA_MOUSE
θ value	6.88961 (rank : 262)	NC score	0.013468 (rank : 384)
Query Neighborhood Hits	312	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NOTC3_HUMAN
θ value	6.88961 (rank : 263)	NC score	0.008193 (rank : 408)
Query Neighborhood Hits	312	Target Neighborhood Hits	1062	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NUFP1_MOUSE
θ value	6.88961 (rank : 264)	NC score	0.014529 (rank : 379)
Query Neighborhood Hits	312	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

RA6I1_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.010467 (rank : 399)
Query Neighborhood Hits	312	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

RGS7_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.013692 (rank : 382)
Query Neighborhood Hits	312	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

SAPS1_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.112222 (rank : 55)
Query Neighborhood Hits	312	Target Neighborhood Hits	704	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SMRC1_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.024667 (rank : 333)
Query Neighborhood Hits	312	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SP4_MOUSE
θ value	6.88961 (rank : 269)	NC score	-0.000306 (rank : 425)
Query Neighborhood Hits	312	Target Neighborhood Hits	759	Shared Neighborhood Hits	18
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

TARA_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.096022 (rank : 80)
Query Neighborhood Hits	312	Target Neighborhood Hits	1626	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TBX2_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.009807 (rank : 401)
Query Neighborhood Hits	312	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TNR6A_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.060781 (rank : 181)
Query Neighborhood Hits	312	Target Neighborhood Hits	343	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

WASF2_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.053858 (rank : 226)
Query Neighborhood Hits	312	Target Neighborhood Hits	315	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WASIP_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.076548 (rank : 117)
Query Neighborhood Hits	312	Target Neighborhood Hits	458	Shared Neighborhood Hits	72
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WNK4_MOUSE
θ value	6.88961 (rank : 275)	NC score	0.014629 (rank : 377)
Query Neighborhood Hits	312	Target Neighborhood Hits	961	Shared Neighborhood Hits	50
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZN358_HUMAN
θ value	6.88961 (rank : 276)	NC score	-0.000930 (rank : 426)
Query Neighborhood Hits	312	Target Neighborhood Hits	840	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

AF9_HUMAN
θ value	8.99809 (rank : 277)	NC score	0.018323 (rank : 355)
Query Neighborhood Hits	312	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

BCL9_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.142364 (rank : 29)
Query Neighborhood Hits	312	Target Neighborhood Hits	1008	Shared Neighborhood Hits	180
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BRSK2_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.003393 (rank : 417)
Query Neighborhood Hits	312	Target Neighborhood Hits	897	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

CAPS2_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.005502 (rank : 414)
Query Neighborhood Hits	312	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

COFA1_MOUSE
θ value	8.99809 (rank : 281)	NC score	0.025683 (rank : 330)
Query Neighborhood Hits	312	Target Neighborhood Hits	305	Shared Neighborhood Hits	47
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CRSP2_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.087157 (rank : 93)
Query Neighborhood Hits	312	Target Neighborhood Hits	380	Shared Neighborhood Hits	93
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CSPG2_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.019969 (rank : 348)
Query Neighborhood Hits	312	Target Neighborhood Hits	711	Shared Neighborhood Hits	45
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DDEF2_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.018003 (rank : 357)
Query Neighborhood Hits	312	Target Neighborhood Hits	599	Shared Neighborhood Hits	44
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

FOXD4_MOUSE
θ value	8.99809 (rank : 285)	NC score	0.006444 (rank : 413)
Query Neighborhood Hits	312	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q60688, Q61573	Gene names	Foxd4, Fkh2, Fkhl9, Freac5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Transcription factor FKH- 2).

GP153_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.008488 (rank : 407)
Query Neighborhood Hits	312	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

HCFC1_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.034781 (rank : 301)
Query Neighborhood Hits	312	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

IF4G3_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.024096 (rank : 335)
Query Neighborhood Hits	312	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K1543_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.069398 (rank : 149)
Query Neighborhood Hits	312	Target Neighborhood Hits	497	Shared Neighborhood Hits	100
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KCNH3_HUMAN
θ value	8.99809 (rank : 290)	NC score	0.020754 (rank : 345)
Query Neighborhood Hits	312	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KIF9_MOUSE
θ value	8.99809 (rank : 291)	NC score	0.001561 (rank : 422)
Query Neighborhood Hits	312	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV04, O35070	Gene names	Kif9
Domain Architecture
Description	Kinesin-like protein KIF9.

MCR_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.002656 (rank : 418)
Query Neighborhood Hits	312	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

MORC2_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.016748 (rank : 362)
Query Neighborhood Hits	312	Target Neighborhood Hits	207	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MYCL1_MOUSE
θ value	8.99809 (rank : 294)	NC score	0.012920 (rank : 387)
Query Neighborhood Hits	312	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NEO1_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.001922 (rank : 421)
Query Neighborhood Hits	312	Target Neighborhood Hits	523	Shared Neighborhood Hits	14
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NFIA_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.013136 (rank : 385)
Query Neighborhood Hits	312	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NUPL2_MOUSE
θ value	8.99809 (rank : 297)	NC score	0.012794 (rank : 389)
Query Neighborhood Hits	312	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

P53_MOUSE
θ value	8.99809 (rank : 298)	NC score	0.007159 (rank : 411)
Query Neighborhood Hits	312	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

PSB4_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.009022 (rank : 405)
Query Neighborhood Hits	312	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P28070, P31148, Q969L6	Gene names	PSMB4
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3) (HSN3) (HsBPROS26).

PSD4_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.014543 (rank : 378)
Query Neighborhood Hits	312	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

RM43_MOUSE
θ value	8.99809 (rank : 301)	NC score	0.012113 (rank : 394)
Query Neighborhood Hits	312	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N89	Gene names	Mrpl43
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L43, mitochondrial precursor (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a).

SHD_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.012947 (rank : 386)
Query Neighborhood Hits	312	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

SOX18_MOUSE
θ value	8.99809 (rank : 303)	NC score	0.016623 (rank : 363)
Query Neighborhood Hits	312	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SRRM1_MOUSE
θ value	8.99809 (rank : 304)	NC score	0.088046 (rank : 91)
Query Neighborhood Hits	312	Target Neighborhood Hits	966	Shared Neighborhood Hits	128
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TGON1_MOUSE
θ value	8.99809 (rank : 305)	NC score	0.038689 (rank : 284)
Query Neighborhood Hits	312	Target Neighborhood Hits	243	Shared Neighborhood Hits	40
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

THAP8_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.018626 (rank : 354)
Query Neighborhood Hits	312	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

ULK1_MOUSE
θ value	8.99809 (rank : 307)	NC score	0.019645 (rank : 352)
Query Neighborhood Hits	312	Target Neighborhood Hits	1214	Shared Neighborhood Hits	112
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

WASF2_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.042898 (rank : 271)
Query Neighborhood Hits	312	Target Neighborhood Hits	280	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

WASL_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.044589 (rank : 267)
Query Neighborhood Hits	312	Target Neighborhood Hits	312	Shared Neighborhood Hits	62
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

WNK4_HUMAN
θ value	8.99809 (rank : 310)	NC score	0.021328 (rank : 343)
Query Neighborhood Hits	312	Target Neighborhood Hits	1043	Shared Neighborhood Hits	72
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

X3CL1_MOUSE
θ value	8.99809 (rank : 311)	NC score	0.012115 (rank : 393)
Query Neighborhood Hits	312	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZIM10_MOUSE
θ value	8.99809 (rank : 312)	NC score	0.043587 (rank : 270)
Query Neighborhood Hits	312	Target Neighborhood Hits	430	Shared Neighborhood Hits	82
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ALEX_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.084420 (rank : 99)
Query Neighborhood Hits	312	Target Neighborhood Hits	361	Shared Neighborhood Hits	82
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ARMX2_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.059621 (rank : 188)
Query Neighborhood Hits	312	Target Neighborhood Hits	349	Shared Neighborhood Hits	94
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ATX2_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.052485 (rank : 238)
Query Neighborhood Hits	312	Target Neighborhood Hits	445	Shared Neighborhood Hits	78
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BAG3_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.053849 (rank : 227)
Query Neighborhood Hits	312	Target Neighborhood Hits	513	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.053648 (rank : 229)
Query Neighborhood Hits	312	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT3_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.056712 (rank : 207)
Query Neighborhood Hits	312	Target Neighborhood Hits	518	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.050758 (rank : 250)
Query Neighborhood Hits	312	Target Neighborhood Hits	744	Shared Neighborhood Hits	113
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BCAR1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.057190 (rank : 201)
Query Neighborhood Hits	312	Target Neighborhood Hits	554	Shared Neighborhood Hits	89
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CD248_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.050696 (rank : 251)
Query Neighborhood Hits	312	Target Neighborhood Hits	679	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.053536 (rank : 231)
Query Neighborhood Hits	312	Target Neighborhood Hits	504	Shared Neighborhood Hits	76
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CECR2_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.067594 (rank : 155)
Query Neighborhood Hits	312	Target Neighborhood Hits	543	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CEL_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.112052 (rank : 56)
Query Neighborhood Hits	312	Target Neighborhood Hits	896	Shared Neighborhood Hits	159
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CJ078_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.064224 (rank : 167)
Query Neighborhood Hits	312	Target Neighborhood Hits	559	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.102631 (rank : 70)
Query Neighborhood Hits	312	Target Neighborhood Hits	408	Shared Neighborhood Hits	97
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CK024_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.069475 (rank : 148)
Query Neighborhood Hits	312	Target Neighborhood Hits	307	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CO002_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.096665 (rank : 79)
Query Neighborhood Hits	312	Target Neighborhood Hits	387	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO039_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.066258 (rank : 158)
Query Neighborhood Hits	312	Target Neighborhood Hits	445	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CPSF6_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.054472 (rank : 224)
Query Neighborhood Hits	312	Target Neighborhood Hits	359	Shared Neighborhood Hits	67
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.053605 (rank : 230)
Query Neighborhood Hits	312	Target Neighborhood Hits	356	Shared Neighborhood Hits	64
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CRTC1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.060859 (rank : 180)
Query Neighborhood Hits	312	Target Neighborhood Hits	319	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

CSF1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.066249 (rank : 159)
Query Neighborhood Hits	312	Target Neighborhood Hits	258	Shared Neighborhood Hits	70
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CT174_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.055123 (rank : 218)
Query Neighborhood Hits	312	Target Neighborhood Hits	181	Shared Neighborhood Hits	44
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DAB1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.061072 (rank : 178)
Query Neighborhood Hits	312	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DAB2_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.073199 (rank : 131)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	55
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DCP1A_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.054176 (rank : 225)
Query Neighborhood Hits	312	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

DOT1L_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.064920 (rank : 162)
Query Neighborhood Hits	312	Target Neighborhood Hits	660	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

ENAM_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.078230 (rank : 112)
Query Neighborhood Hits	312	Target Neighborhood Hits	229	Shared Neighborhood Hits	57
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

FA47A_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.071815 (rank : 134)
Query Neighborhood Hits	312	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.074745 (rank : 128)
Query Neighborhood Hits	312	Target Neighborhood Hits	431	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GGN_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.055300 (rank : 217)
Query Neighborhood Hits	312	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GNAS1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.057089 (rank : 202)
Query Neighborhood Hits	312	Target Neighborhood Hits	651	Shared Neighborhood Hits	121
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GPS2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.053150 (rank : 234)
Query Neighborhood Hits	312	Target Neighborhood Hits	459	Shared Neighborhood Hits	55
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GRIN1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.085119 (rank : 97)
Query Neighborhood Hits	312	Target Neighborhood Hits	681	Shared Neighborhood Hits	123
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HRBL_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.062755 (rank : 169)
Query Neighborhood Hits	312	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

IASPP_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.067082 (rank : 157)
Query Neighborhood Hits	312	Target Neighborhood Hits	1024	Shared Neighborhood Hits	134
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IF4G1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.073231 (rank : 130)
Query Neighborhood Hits	312	Target Neighborhood Hits	534	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K0240_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.053768 (rank : 228)
Query Neighborhood Hits	312	Target Neighborhood Hits	211	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

K1543_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.070907 (rank : 141)
Query Neighborhood Hits	312	Target Neighborhood Hits	435	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

K1683_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.062362 (rank : 171)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

LAD1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.060682 (rank : 184)
Query Neighborhood Hits	312	Target Neighborhood Hits	441	Shared Neighborhood Hits	64
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

LAD1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.053246 (rank : 233)
Query Neighborhood Hits	312	Target Neighborhood Hits	391	Shared Neighborhood Hits	54
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LCP2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.081023 (rank : 105)
Query Neighborhood Hits	312	Target Neighborhood Hits	531	Shared Neighborhood Hits	102
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LEUK_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.071112 (rank : 140)
Query Neighborhood Hits	312	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

LPP_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.085133 (rank : 96)
Query Neighborhood Hits	312	Target Neighborhood Hits	775	Shared Neighborhood Hits	141
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

LR37A_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.059463 (rank : 189)
Query Neighborhood Hits	312	Target Neighborhood Hits	720	Shared Neighborhood Hits	94
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAML1_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.061190 (rank : 177)
Query Neighborhood Hits	312	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAP4_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.057201 (rank : 200)
Query Neighborhood Hits	312	Target Neighborhood Hits	428	Shared Neighborhood Hits	70
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAP4_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.054760 (rank : 223)
Query Neighborhood Hits	312	Target Neighborhood Hits	409	Shared Neighborhood Hits	67
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAVS_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.056730 (rank : 204)
Query Neighborhood Hits	312	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MAVS_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.051426 (rank : 246)
Query Neighborhood Hits	312	Target Neighborhood Hits	170	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MDC1_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.145946 (rank : 27)
Query Neighborhood Hits	312	Target Neighborhood Hits	1446	Shared Neighborhood Hits	173
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MINT_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.062099 (rank : 174)
Query Neighborhood Hits	312	Target Neighborhood Hits	1514	Shared Neighborhood Hits	151
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MKL1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.051736 (rank : 243)
Query Neighborhood Hits	312	Target Neighborhood Hits	667	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL3_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.137997 (rank : 33)
Query Neighborhood Hits	312	Target Neighborhood Hits	1644	Shared Neighborhood Hits	194
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MTSS1_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.058806 (rank : 192)
Query Neighborhood Hits	312	Target Neighborhood Hits	592	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC13_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.055968 (rank : 211)
Query Neighborhood Hits	312	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.055633 (rank : 216)
Query Neighborhood Hits	312	Target Neighborhood Hits	388	Shared Neighborhood Hits	60
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC5B_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.059803 (rank : 187)
Query Neighborhood Hits	312	Target Neighborhood Hits	1020	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MUCDL_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.097339 (rank : 76)
Query Neighborhood Hits	312	Target Neighborhood Hits	777	Shared Neighborhood Hits	127
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCOA6_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.136477 (rank : 37)
Query Neighborhood Hits	312	Target Neighborhood Hits	1076	Shared Neighborhood Hits	181
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFRKB_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.075613 (rank : 123)
Query Neighborhood Hits	312	Target Neighborhood Hits	393	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NRX2B_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.072213 (rank : 132)
Query Neighborhood Hits	312	Target Neighborhood Hits	481	Shared Neighborhood Hits	109
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

OBF1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.059248 (rank : 190)
Query Neighborhood Hits	312	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

OGFR_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.162225 (rank : 18)
Query Neighborhood Hits	312	Target Neighborhood Hits	1582	Shared Neighborhood Hits	215
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.056724 (rank : 205)
Query Neighborhood Hits	312	Target Neighborhood Hits	584	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PCQAP_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.055689 (rank : 214)
Query Neighborhood Hits	312	Target Neighborhood Hits	506	Shared Neighborhood Hits	56
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PDZD2_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.053363 (rank : 232)
Query Neighborhood Hits	312	Target Neighborhood Hits	772	Shared Neighborhood Hits	115
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PELP1_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.064825 (rank : 163)
Query Neighborhood Hits	312	Target Neighborhood Hits	596	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PER3_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.065278 (rank : 161)
Query Neighborhood Hits	312	Target Neighborhood Hits	479	Shared Neighborhood Hits	109
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PICAL_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.054903 (rank : 220)
Query Neighborhood Hits	312	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

PICA_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.057045 (rank : 203)
Query Neighborhood Hits	312	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

PRB3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.057733 (rank : 196)
Query Neighborhood Hits	312	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.061200 (rank : 176)
Query Neighborhood Hits	312	Target Neighborhood Hits	330	Shared Neighborhood Hits	57
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.082715 (rank : 103)
Query Neighborhood Hits	312	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.105791 (rank : 64)
Query Neighborhood Hits	312	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR13_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.064562 (rank : 166)
Query Neighborhood Hits	312	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRRT3_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.187280 (rank : 11)
Query Neighborhood Hits	312	Target Neighborhood Hits	998	Shared Neighborhood Hits	174
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.094808 (rank : 82)
Query Neighborhood Hits	312	Target Neighborhood Hits	1375	Shared Neighborhood Hits	187
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RPC1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.051993 (rank : 241)
Query Neighborhood Hits	312	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

RTP3_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.075377 (rank : 124)
Query Neighborhood Hits	312	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SC24A_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.056282 (rank : 208)
Query Neighborhood Hits	312	Target Neighborhood Hits	394	Shared Neighborhood Hits	89
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SELPL_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.098946 (rank : 75)
Query Neighborhood Hits	312	Target Neighborhood Hits	588	Shared Neighborhood Hits	112
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SEPT9_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.052981 (rank : 236)
Query Neighborhood Hits	312	Target Neighborhood Hits	706	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SET1A_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.058958 (rank : 191)
Query Neighborhood Hits	312	Target Neighborhood Hits	690	Shared Neighborhood Hits	78
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SF3A2_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.050045 (rank : 254)
Query Neighborhood Hits	312	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3B1_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.075233 (rank : 125)
Query Neighborhood Hits	312	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.076140 (rank : 119)
Query Neighborhood Hits	312	Target Neighborhood Hits	352	Shared Neighborhood Hits	72
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SFPQ_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.058519 (rank : 194)
Query Neighborhood Hits	312	Target Neighborhood Hits	986	Shared Neighborhood Hits	96
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SNPC4_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.069329 (rank : 150)
Query Neighborhood Hits	312	Target Neighborhood Hits	589	Shared Neighborhood Hits	122
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SON_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.141239 (rank : 31)
Query Neighborhood Hits	312	Target Neighborhood Hits	1568	Shared Neighborhood Hits	205
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR1A_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.052234 (rank : 240)
Query Neighborhood Hits	312	Target Neighborhood Hits	343	Shared Neighborhood Hits	69
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPR1B_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.064620 (rank : 165)
Query Neighborhood Hits	312	Target Neighborhood Hits	395	Shared Neighborhood Hits	84
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SPT5H_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.070051 (rank : 145)
Query Neighborhood Hits	312	Target Neighborhood Hits	436	Shared Neighborhood Hits	94
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.070875 (rank : 142)
Query Neighborhood Hits	312	Target Neighborhood Hits	437	Shared Neighborhood Hits	96
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRRM1_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.058018 (rank : 195)
Query Neighborhood Hits	312	Target Neighborhood Hits	690	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SYN1_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.062234 (rank : 173)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	67
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYNJ2_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.052448 (rank : 239)
Query Neighborhood Hits	312	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

T22D4_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.083628 (rank : 101)
Query Neighborhood Hits	312	Target Neighborhood Hits	403	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TARA_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.070264 (rank : 144)
Query Neighborhood Hits	312	Target Neighborhood Hits	1133	Shared Neighborhood Hits	113
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.105533 (rank : 65)
Query Neighborhood Hits	312	Target Neighborhood Hits	768	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TAU_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.051335 (rank : 247)
Query Neighborhood Hits	312	Target Neighborhood Hits	448	Shared Neighborhood Hits	88
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TAU_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.061815 (rank : 175)
Query Neighborhood Hits	312	Target Neighborhood Hits	502	Shared Neighborhood Hits	103
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCF19_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.067234 (rank : 156)
Query Neighborhood Hits	312	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

TCOF_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.051650 (rank : 244)
Query Neighborhood Hits	312	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TM108_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.082782 (rank : 102)
Query Neighborhood Hits	312	Target Neighborhood Hits	336	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TP53B_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.071428 (rank : 137)
Query Neighborhood Hits	312	Target Neighborhood Hits	644	Shared Neighborhood Hits	92
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TPO_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.054857 (rank : 221)
Query Neighborhood Hits	312	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TXND2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.068569 (rank : 153)
Query Neighborhood Hits	312	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASIP_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.076326 (rank : 118)
Query Neighborhood Hits	312	Target Neighborhood Hits	392	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WIRE_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.056278 (rank : 209)
Query Neighborhood Hits	312	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.054786 (rank : 222)
Query Neighborhood Hits	312	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.075878 (rank : 120)
Query Neighborhood Hits	312	Target Neighborhood Hits	670	Shared Neighborhood Hits	102
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZIM10_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.060256 (rank : 186)
Query Neighborhood Hits	312	Target Neighborhood Hits	577	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZIMP7_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.083672 (rank : 100)
Query Neighborhood Hits	312	Target Neighborhood Hits	566	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN207_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.051117 (rank : 249)
Query Neighborhood Hits	312	Target Neighborhood Hits	326	Shared Neighborhood Hits	44
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN385_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.071783 (rank : 135)
Query Neighborhood Hits	312	Target Neighborhood Hits	614	Shared Neighborhood Hits	106
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

Hits sorted by NC score

EPN3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	312	Target Neighborhood Hits	312	Shared Neighborhood Hits	312
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPN3_HUMAN
NC score	0.934206 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

EPN2_MOUSE
NC score	0.883587 (rank : 3)	θ value	4.19693e-98 (rank : 5)
Query Neighborhood Hits	312	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CHU3, O70447, Q8BZ85	Gene names	Epn2
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2).

EPN2_HUMAN
NC score	0.879599 (rank : 4)	θ value	1.22395e-89 (rank : 6)
Query Neighborhood Hits	312	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

EPN1_MOUSE
NC score	0.862774 (rank : 5)	θ value	4.6295e-105 (rank : 3)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

EPN1_HUMAN
NC score	0.862215 (rank : 6)	θ value	5.11853e-104 (rank : 4)
Query Neighborhood Hits	312	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN4_HUMAN
NC score	0.779611 (rank : 7)	θ value	2.58786e-39 (rank : 7)
Query Neighborhood Hits	312	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

EPN4_MOUSE
NC score	0.777298 (rank : 8)	θ value	2.58786e-39 (rank : 8)
Query Neighborhood Hits	312	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

MUC1_HUMAN
NC score	0.191093 (rank : 9)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	312	Target Neighborhood Hits	975	Shared Neighborhood Hits	172
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NACAM_MOUSE
NC score	0.187286 (rank : 10)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	312	Target Neighborhood Hits	1866	Shared Neighborhood Hits	214
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PRRT3_HUMAN
NC score	0.187280 (rank : 11)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	312	Target Neighborhood Hits	998	Shared Neighborhood Hits	174
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CN032_HUMAN
NC score	0.176834 (rank : 12)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	312	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

BSN_MOUSE
NC score	0.170973 (rank : 13)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	312	Target Neighborhood Hits	2057	Shared Neighborhood Hits	214
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MISS_MOUSE
NC score	0.166065 (rank : 14)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	312	Target Neighborhood Hits	444	Shared Neighborhood Hits	97
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

NCOA6_HUMAN
NC score	0.164979 (rank : 15)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	312	Target Neighborhood Hits	1202	Shared Neighborhood Hits	195
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CN032_MOUSE
NC score	0.164457 (rank : 16)	θ value	0.0113563 (rank : 35)
Query Neighborhood Hits	312	Target Neighborhood Hits	233	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CS016_HUMAN
NC score	0.162536 (rank : 17)	θ value	0.00175202 (rank : 20)
Query Neighborhood Hits	312	Target Neighborhood Hits	310	Shared Neighborhood Hits	58
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

OGFR_HUMAN
NC score	0.162225 (rank : 18)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	312	Target Neighborhood Hits	1582	Shared Neighborhood Hits	215
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MDC1_MOUSE
NC score	0.155316 (rank : 19)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	312	Target Neighborhood Hits	998	Shared Neighborhood Hits	146
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

GSCR1_HUMAN
NC score	0.155311 (rank : 20)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	312	Target Neighborhood Hits	674	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MUC7_HUMAN
NC score	0.154678 (rank : 21)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	312	Target Neighborhood Hits	538	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

K1802_MOUSE
NC score	0.151227 (rank : 22)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	312	Target Neighborhood Hits	1596	Shared Neighborhood Hits	185
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RPB1_MOUSE
NC score	0.147614 (rank : 23)	θ value	4.1701e-05 (rank : 10)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	55
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.147405 (rank : 24)	θ value	4.1701e-05 (rank : 9)
Query Neighborhood Hits	312	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RGS3_MOUSE
NC score	0.146355 (rank : 25)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	312	Target Neighborhood Hits	1621	Shared Neighborhood Hits	225
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AP180_MOUSE
NC score	0.146274 (rank : 26)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	312	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

MDC1_HUMAN
NC score	0.145946 (rank : 27)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	312	Target Neighborhood Hits	1446	Shared Neighborhood Hits	173
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PI5PA_HUMAN
NC score	0.144770 (rank : 28)	θ value	0.62314 (rank : 110)
Query Neighborhood Hits	312	Target Neighborhood Hits	749	Shared Neighborhood Hits	157
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BCL9_HUMAN
NC score	0.142364 (rank : 29)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	312	Target Neighborhood Hits	1008	Shared Neighborhood Hits	180
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MLL3_MOUSE
NC score	0.141629 (rank : 30)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	312	Target Neighborhood Hits	1399	Shared Neighborhood Hits	170
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SON_HUMAN
NC score	0.141239 (rank : 31)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	312	Target Neighborhood Hits	1568	Shared Neighborhood Hits	205
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NU214_HUMAN
NC score	0.140476 (rank : 32)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	312	Target Neighborhood Hits	657	Shared Neighborhood Hits	90
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MLL3_HUMAN
NC score	0.137997 (rank : 33)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	312	Target Neighborhood Hits	1644	Shared Neighborhood Hits	194
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CIC_HUMAN
NC score	0.137823 (rank : 34)	θ value	0.0113563 (rank : 34)
Query Neighborhood Hits	312	Target Neighborhood Hits	992	Shared Neighborhood Hits	168
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

K1802_HUMAN
NC score	0.137748 (rank : 35)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	312	Target Neighborhood Hits	1378	Shared Neighborhood Hits	160
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAGE1_HUMAN
NC score	0.137459 (rank : 36)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	312	Target Neighborhood Hits	1389	Shared Neighborhood Hits	204
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NCOA6_MOUSE
NC score	0.136477 (rank : 37)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	312	Target Neighborhood Hits	1076	Shared Neighborhood Hits	181
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TAF4_HUMAN
NC score	0.127405 (rank : 38)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	312	Target Neighborhood Hits	687	Shared Neighborhood Hits	94
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRG4_HUMAN
NC score	0.126009 (rank : 39)	θ value	9.29e-05 (rank : 12)
Query Neighborhood Hits	312	Target Neighborhood Hits	764	Shared Neighborhood Hits	96
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CIC_MOUSE
NC score	0.125184 (rank : 40)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	312	Target Neighborhood Hits	742	Shared Neighborhood Hits	139
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

AP180_HUMAN
NC score	0.123348 (rank : 41)	θ value	0.000461057 (rank : 16)
Query Neighborhood Hits	312	Target Neighborhood Hits	183	Shared Neighborhood Hits	43
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

PCLO_HUMAN
NC score	0.122929 (rank : 42)	θ value	0.0193708 (rank : 39)
Query Neighborhood Hits	312	Target Neighborhood Hits	2046	Shared Neighborhood Hits	183
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SSBP4_HUMAN
NC score	0.121619 (rank : 43)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	312	Target Neighborhood Hits	753	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

BAT2_HUMAN
NC score	0.121582 (rank : 44)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	312	Target Neighborhood Hits	931	Shared Neighborhood Hits	139
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_MOUSE
NC score	0.120711 (rank : 45)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	312	Target Neighborhood Hits	2275	Shared Neighborhood Hits	214
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PS1C2_MOUSE
NC score	0.120556 (rank : 46)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	312	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q80ZC9	Gene names	Psors1c2, Spr1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein homolog precursor (SPR1 protein).

PELP1_MOUSE
NC score	0.119678 (rank : 47)	θ value	7.1131e-05 (rank : 11)
Query Neighborhood Hits	312	Target Neighborhood Hits	709	Shared Neighborhood Hits	112
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

BSN_HUMAN
NC score	0.119228 (rank : 48)	θ value	0.62314 (rank : 108)
Query Neighborhood Hits	312	Target Neighborhood Hits	1537	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PS1C2_HUMAN
NC score	0.116341 (rank : 49)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	312	Target Neighborhood Hits	66	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

BAT2_MOUSE
NC score	0.115842 (rank : 50)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	312	Target Neighborhood Hits	947	Shared Neighborhood Hits	141
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SRRM2_MOUSE
NC score	0.114960 (rank : 51)	θ value	1.38821 (rank : 154)
Query Neighborhood Hits	312	Target Neighborhood Hits	1470	Shared Neighborhood Hits	159
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BCL9_MOUSE
NC score	0.114740 (rank : 52)	θ value	0.62314 (rank : 107)
Query Neighborhood Hits	312	Target Neighborhood Hits	770	Shared Neighborhood Hits	154
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PSL1_HUMAN
NC score	0.113065 (rank : 53)	θ value	0.813845 (rank : 120)
Query Neighborhood Hits	312	Target Neighborhood Hits	650	Shared Neighborhood Hits	149
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ARI1A_HUMAN
NC score	0.112918 (rank : 54)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	312	Target Neighborhood Hits	787	Shared Neighborhood Hits	124
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

SAPS1_HUMAN
NC score	0.112222 (rank : 55)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	312	Target Neighborhood Hits	704	Shared Neighborhood Hits	151
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CEL_HUMAN
NC score	0.112052 (rank : 56)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	312	Target Neighborhood Hits	896	Shared Neighborhood Hits	159
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SYNJ1_MOUSE
NC score	0.112025 (rank : 57)	θ value	0.00102713 (rank : 18)
Query Neighborhood Hits	312	Target Neighborhood Hits	516	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SC24C_HUMAN
NC score	0.110570 (rank : 58)	θ value	3.0926 (rank : 205)
Query Neighborhood Hits	312	Target Neighborhood Hits	662	Shared Neighborhood Hits	135
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SON_MOUSE
NC score	0.109546 (rank : 59)	θ value	1.38821 (rank : 153)
Query Neighborhood Hits	312	Target Neighborhood Hits	957	Shared Neighborhood Hits	144
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MLL2_HUMAN
NC score	0.109221 (rank : 60)	θ value	0.00665767 (rank : 31)
Query Neighborhood Hits	312	Target Neighborhood Hits	1788	Shared Neighborhood Hits	162
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CABIN_HUMAN
NC score	0.108845 (rank : 61)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	312	Target Neighborhood Hits	490	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

ENAH_MOUSE
NC score	0.108339 (rank : 62)	θ value	0.000270298 (rank : 15)
Query Neighborhood Hits	312	Target Neighborhood Hits	919	Shared Neighborhood Hits	100
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

TCGAP_HUMAN
NC score	0.108142 (rank : 63)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	312	Target Neighborhood Hits	872	Shared Neighborhood Hits	141
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PRP2_MOUSE
NC score	0.105791 (rank : 64)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	312	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TARSH_HUMAN
NC score	0.105533 (rank : 65)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	312	Target Neighborhood Hits	768	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

ATN1_HUMAN
NC score	0.103661 (rank : 66)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	312	Target Neighborhood Hits	676	Shared Neighborhood Hits	95
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

SYNJ1_HUMAN
NC score	0.103569 (rank : 67)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	312	Target Neighborhood Hits	498	Shared Neighborhood Hits	93
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

NFH_MOUSE
NC score	0.103291 (rank : 68)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	312	Target Neighborhood Hits	2247	Shared Neighborhood Hits	208
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PO121_MOUSE
NC score	0.102675 (rank : 69)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	312	Target Neighborhood Hits	345	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

CK024_HUMAN
NC score	0.102631 (rank : 70)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	312	Target Neighborhood Hits	408	Shared Neighborhood Hits	97
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

DIDO1_HUMAN
NC score	0.102369 (rank : 71)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	312	Target Neighborhood Hits	960	Shared Neighborhood Hits	133
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ZN750_MOUSE
NC score	0.101210 (rank : 72)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	312	Target Neighborhood Hits	346	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CBP_MOUSE
NC score	0.099653 (rank : 73)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	312	Target Neighborhood Hits	1051	Shared Neighborhood Hits	147
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ALEX_MOUSE
NC score	0.098980 (rank : 74)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	48
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SELPL_MOUSE
NC score	0.098946 (rank : 75)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	312	Target Neighborhood Hits	588	Shared Neighborhood Hits	112
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

MUCDL_HUMAN
NC score	0.097339 (rank : 76)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	312	Target Neighborhood Hits	777	Shared Neighborhood Hits	127
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SRRM2_HUMAN
NC score	0.096942 (rank : 77)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	312	Target Neighborhood Hits	1296	Shared Neighborhood Hits	119
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

K0329_HUMAN
NC score	0.096799 (rank : 78)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	312	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

CO002_HUMAN
NC score	0.096665 (rank : 79)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	312	Target Neighborhood Hits	387	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

TARA_HUMAN
NC score	0.096022 (rank : 80)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	312	Target Neighborhood Hits	1626	Shared Neighborhood Hits	164
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

K0310_HUMAN
NC score	0.095435 (rank : 81)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	312	Target Neighborhood Hits	420	Shared Neighborhood Hits	88
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

RGS3_HUMAN
NC score	0.094808 (rank : 82)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	312	Target Neighborhood Hits	1375	Shared Neighborhood Hits	187
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PO121_HUMAN
NC score	0.094184 (rank : 83)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	312	Target Neighborhood Hits	344	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CBP_HUMAN
NC score	0.094145 (rank : 84)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	312	Target Neighborhood Hits	941	Shared Neighborhood Hits	144
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HRBL_HUMAN
NC score	0.093709 (rank : 85)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	312	Target Neighborhood Hits	179	Shared Neighborhood Hits	45
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

RERE_MOUSE
NC score	0.093095 (rank : 86)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	312	Target Neighborhood Hits	785	Shared Neighborhood Hits	96
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

PRR12_HUMAN
NC score	0.092505 (rank : 87)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	312	Target Neighborhood Hits	460	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MBD6_HUMAN
NC score	0.090864 (rank : 88)	θ value	1.81305 (rank : 167)
Query Neighborhood Hits	312	Target Neighborhood Hits	349	Shared Neighborhood Hits	69
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

ARI1B_HUMAN
NC score	0.088977 (rank : 89)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	312	Target Neighborhood Hits	567	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

EP300_HUMAN
NC score	0.088295 (rank : 90)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	312	Target Neighborhood Hits	821	Shared Neighborhood Hits	118
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SRRM1_MOUSE
NC score	0.088046 (rank : 91)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	312	Target Neighborhood Hits	966	Shared Neighborhood Hits	128
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RERE_HUMAN
NC score	0.087270 (rank : 92)	θ value	0.813845 (rank : 121)
Query Neighborhood Hits	312	Target Neighborhood Hits	779	Shared Neighborhood Hits	94
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

CRSP2_HUMAN
NC score	0.087157 (rank : 93)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	312	Target Neighborhood Hits	380	Shared Neighborhood Hits	93
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

MUC2_HUMAN
NC score	0.086196 (rank : 94)	θ value	0.00665767 (rank : 32)
Query Neighborhood Hits	312	Target Neighborhood Hits	906	Shared Neighborhood Hits	93
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

DAB2_MOUSE
NC score	0.085463 (rank : 95)	θ value	0.00020696 (rank : 14)
Query Neighborhood Hits	312	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

LPP_HUMAN
NC score	0.085133 (rank : 96)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	312	Target Neighborhood Hits	775	Shared Neighborhood Hits	141
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

GRIN1_HUMAN
NC score	0.085119 (rank : 97)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	312	Target Neighborhood Hits	681	Shared Neighborhood Hits	123
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TGON2_HUMAN
NC score	0.084958 (rank : 98)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	312	Target Neighborhood Hits	1037	Shared Neighborhood Hits	108
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ALEX_HUMAN
NC score	0.084420 (rank : 99)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	312	Target Neighborhood Hits	361	Shared Neighborhood Hits	82
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ZIMP7_MOUSE
NC score	0.083672 (rank : 100)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	312	Target Neighborhood Hits	566	Shared Neighborhood Hits	128
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

T22D4_HUMAN
NC score	0.083628 (rank : 101)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	312	Target Neighborhood Hits	403	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

TM108_MOUSE
NC score	0.082782 (rank : 102)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	312	Target Neighborhood Hits	336	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

PRP1_HUMAN
NC score	0.082715 (rank : 103)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	312	Target Neighborhood Hits	385	Shared Neighborhood Hits	65
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PI5PA_MOUSE
NC score	0.081905 (rank : 104)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	312	Target Neighborhood Hits	331	Shared Neighborhood Hits	67
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

LCP2_HUMAN
NC score	0.081023 (rank : 105)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	312	Target Neighborhood Hits	531	Shared Neighborhood Hits	102
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PRG4_MOUSE
NC score	0.080838 (rank : 106)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	312	Target Neighborhood Hits	624	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WBP11_HUMAN
NC score	0.079950 (rank : 107)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	312	Target Neighborhood Hits	354	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

R51A1_MOUSE
NC score	0.079469 (rank : 108)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	312	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

T22D2_HUMAN
NC score	0.079138 (rank : 109)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	312	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

SF01_MOUSE
NC score	0.078306 (rank : 110)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	49
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

GGN_MOUSE
NC score	0.078235 (rank : 111)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	312	Target Neighborhood Hits	311	Shared Neighborhood Hits	64
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

ENAM_MOUSE
NC score	0.078230 (rank : 112)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	312	Target Neighborhood Hits	229	Shared Neighborhood Hits	57
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

PCQAP_HUMAN
NC score	0.077833 (rank : 113)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	312	Target Neighborhood Hits	549	Shared Neighborhood Hits	63
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

YLPM1_MOUSE
NC score	0.077269 (rank : 114)	θ value	0.47712 (rank : 105)
Query Neighborhood Hits	312	Target Neighborhood Hits	505	Shared Neighborhood Hits	74
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

FOSB_HUMAN
NC score	0.076963 (rank : 115)	θ value	0.0252991 (rank : 40)
Query Neighborhood Hits	312	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

WBP11_MOUSE
NC score	0.076779 (rank : 116)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	312	Target Neighborhood Hits	362	Shared Neighborhood Hits	60
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WASIP_HUMAN
NC score	0.076548 (rank : 117)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	312	Target Neighborhood Hits	458	Shared Neighborhood Hits	72
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
NC score	0.076326 (rank : 118)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	312	Target Neighborhood Hits	392	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

SF3B1_MOUSE
NC score	0.076140 (rank : 119)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	312	Target Neighborhood Hits	352	Shared Neighborhood Hits	72
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

YLPM1_HUMAN
NC score	0.075878 (rank : 120)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	312	Target Neighborhood Hits	670	Shared Neighborhood Hits	102
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

FOSB_MOUSE
NC score	0.075838 (rank : 121)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	312	Target Neighborhood Hits	137	Shared Neighborhood Hits	14
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

TCOF_MOUSE
NC score	0.075741 (rank : 122)	θ value	0.62314 (rank : 114)
Query Neighborhood Hits	312	Target Neighborhood Hits	471	Shared Neighborhood Hits	58
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

NFRKB_MOUSE
NC score	0.075613 (rank : 123)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	312	Target Neighborhood Hits	393	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RTP3_MOUSE
NC score	0.075377 (rank : 124)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	312	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SF3B1_HUMAN
NC score	0.075233 (rank : 125)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	312	Target Neighborhood Hits	341	Shared Neighborhood Hits	70
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CG1_HUMAN
NC score	0.075214 (rank : 126)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	312	Target Neighborhood Hits	222	Shared Neighborhood Hits	58
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

SF01_HUMAN
NC score	0.075010 (rank : 127)	θ value	0.62314 (rank : 111)
Query Neighborhood Hits	312	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

FA47B_HUMAN
NC score	0.074745 (rank : 128)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	312	Target Neighborhood Hits	431	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TB182_HUMAN
NC score	0.074595 (rank : 129)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	312	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

IF4G1_MOUSE
NC score	0.073231 (rank : 130)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	312	Target Neighborhood Hits	534	Shared Neighborhood Hits	100
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

DAB2_HUMAN
NC score	0.073199 (rank : 131)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	312	Target Neighborhood Hits	197	Shared Neighborhood Hits	55
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

NRX2B_HUMAN
NC score	0.072213 (rank : 132)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	312	Target Neighborhood Hits	481	Shared Neighborhood Hits	109
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

MBB1A_HUMAN
NC score	0.072170 (rank : 133)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	312	Target Neighborhood Hits	665	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

FA47A_HUMAN
NC score	0.071815 (rank : 134)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	312	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

ZN385_HUMAN
NC score	0.071783 (rank : 135)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	312	Target Neighborhood Hits	614	Shared Neighborhood Hits	106
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

JPH2_HUMAN
NC score	0.071477 (rank : 136)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	312	Target Neighborhood Hits	639	Shared Neighborhood Hits	120
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TP53B_MOUSE
NC score	0.071428 (rank : 137)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	312	Target Neighborhood Hits	644	Shared Neighborhood Hits	92
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MAP1A_HUMAN
NC score	0.071313 (rank : 138)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	312	Target Neighborhood Hits	1626	Shared Neighborhood Hits	148
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

S23IP_MOUSE
NC score	0.071215 (rank : 139)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	79
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

LEUK_HUMAN
NC score	0.071112 (rank : 140)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	312	Target Neighborhood Hits	213	Shared Neighborhood Hits	53
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

K1543_HUMAN
NC score	0.070907 (rank : 141)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	312	Target Neighborhood Hits	435	Shared Neighborhood Hits	101
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SPT5H_MOUSE
NC score	0.070875 (rank : 142)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	312	Target Neighborhood Hits	437	Shared Neighborhood Hits	96
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

MILK1_MOUSE
NC score	0.070735 (rank : 143)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	312	Target Neighborhood Hits	788	Shared Neighborhood Hits	131
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TARA_MOUSE
NC score	0.070264 (rank : 144)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	312	Target Neighborhood Hits	1133	Shared Neighborhood Hits	113
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SPT5H_HUMAN
NC score	0.070051 (rank : 145)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	312	Target Neighborhood Hits	436	Shared Neighborhood Hits	94
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

R3HD2_MOUSE
NC score	0.070021 (rank : 146)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	312	Target Neighborhood Hits	397	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

NCOR2_HUMAN
NC score	0.069826 (rank : 147)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	312	Target Neighborhood Hits	870	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

CK024_MOUSE
NC score	0.069475 (rank : 148)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	312	Target Neighborhood Hits	307	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

K1543_MOUSE
NC score	0.069398 (rank : 149)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	312	Target Neighborhood Hits	497	Shared Neighborhood Hits	100
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SNPC4_HUMAN
NC score	0.069329 (rank : 150)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	312	Target Neighborhood Hits	589	Shared Neighborhood Hits	122
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CNOT3_HUMAN
NC score	0.068937 (rank : 151)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	312	Target Neighborhood Hits	425	Shared Neighborhood Hits	55
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SYN1_HUMAN
NC score	0.068779 (rank : 152)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	312	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TXND2_HUMAN
NC score	0.068569 (rank : 153)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	312	Target Neighborhood Hits	793	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MLL4_HUMAN
NC score	0.067642 (rank : 154)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	312	Target Neighborhood Hits	722	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

CECR2_HUMAN
NC score	0.067594 (rank : 155)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	312	Target Neighborhood Hits	543	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

TCF19_HUMAN
NC score	0.067234 (rank : 156)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	312	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

IASPP_MOUSE
NC score	0.067082 (rank : 157)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	312	Target Neighborhood Hits	1024	Shared Neighborhood Hits	134
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CO039_MOUSE
NC score	0.066258 (rank : 158)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	312	Target Neighborhood Hits	445	Shared Neighborhood Hits	106
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CSF1_HUMAN
NC score	0.066249 (rank : 159)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	312	Target Neighborhood Hits	258	Shared Neighborhood Hits	70
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CNOT3_MOUSE
NC score	0.065678 (rank : 160)	θ value	1.81305 (rank : 159)
Query Neighborhood Hits	312	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PER3_HUMAN
NC score	0.065278 (rank : 161)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	312	Target Neighborhood Hits	479	Shared Neighborhood Hits	109
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

DOT1L_HUMAN
NC score	0.064920 (rank : 162)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	312	Target Neighborhood Hits	660	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PELP1_HUMAN
NC score	0.064825 (rank : 163)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	312	Target Neighborhood Hits	596	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SYN3_MOUSE
NC score	0.064717 (rank : 164)	θ value	0.00869519 (rank : 33)
Query Neighborhood Hits	312	Target Neighborhood Hits	200	Shared Neighborhood Hits	43
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SPR1B_MOUSE
NC score	0.064620 (rank : 165)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	312	Target Neighborhood Hits	395	Shared Neighborhood Hits	84
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PRR13_HUMAN
NC score	0.064562 (rank : 166)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	312	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CJ078_MOUSE
NC score	0.064224 (rank : 167)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	312	Target Neighborhood Hits	559	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

RAPH1_HUMAN
NC score	0.063859 (rank : 168)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	312	Target Neighborhood Hits	593	Shared Neighborhood Hits	90
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

HRBL_MOUSE
NC score	0.062755 (rank : 169)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	312	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

IF4G1_HUMAN
NC score	0.062410 (rank : 170)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	312	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

K1683_HUMAN
NC score	0.062362 (rank : 171)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CS007_MOUSE
NC score	0.062324 (rank : 172)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	312	Target Neighborhood Hits	464	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SYN1_MOUSE
NC score	0.062234 (rank : 173)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	312	Target Neighborhood Hits	363	Shared Neighborhood Hits	67
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

MINT_MOUSE
NC score	0.062099 (rank : 174)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	312	Target Neighborhood Hits	1514	Shared Neighborhood Hits	151
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TAU_MOUSE
NC score	0.061815 (rank : 175)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	312	Target Neighborhood Hits	502	Shared Neighborhood Hits	103
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PRB4S_HUMAN
NC score	0.061200 (rank : 176)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	312	Target Neighborhood Hits	330	Shared Neighborhood Hits	57
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

MAML1_MOUSE
NC score	0.061190 (rank : 177)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	312	Target Neighborhood Hits	279	Shared Neighborhood Hits	59
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

DAB1_HUMAN
NC score	0.061072 (rank : 178)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	312	Target Neighborhood Hits	219	Shared Neighborhood Hits	65
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

LEUK_MOUSE
NC score	0.060959 (rank : 179)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	312	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

CRTC1_HUMAN
NC score	0.060859 (rank : 180)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	312	Target Neighborhood Hits	319	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

TNR6A_HUMAN
NC score	0.060781 (rank : 181)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	312	Target Neighborhood Hits	343	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

EP15R_MOUSE
NC score	0.060741 (rank : 182)	θ value	0.000461057 (rank : 17)
Query Neighborhood Hits	312	Target Neighborhood Hits	1135	Shared Neighborhood Hits	47
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

SYNPO_MOUSE
NC score	0.060695 (rank : 183)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	312	Target Neighborhood Hits	242	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

LAD1_HUMAN
NC score	0.060682 (rank : 184)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	312	Target Neighborhood Hits	441	Shared Neighborhood Hits	64
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

ATX7_MOUSE
NC score	0.060597 (rank : 185)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	312	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

ZIM10_HUMAN
NC score	0.060256 (rank : 186)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	312	Target Neighborhood Hits	577	Shared Neighborhood Hits	101
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

MUC5B_HUMAN
NC score	0.059803 (rank : 187)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	312	Target Neighborhood Hits	1020	Shared Neighborhood Hits	87
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ARMX2_MOUSE
NC score	0.059621 (rank : 188)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	312	Target Neighborhood Hits	349	Shared Neighborhood Hits	94
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

LR37A_HUMAN
NC score	0.059463 (rank : 189)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	312	Target Neighborhood Hits	720	Shared Neighborhood Hits	94
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

OBF1_HUMAN
NC score	0.059248 (rank : 190)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	312	Target Neighborhood Hits	203	Shared Neighborhood Hits	57
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

SET1A_HUMAN
NC score	0.058958 (rank : 191)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	312	Target Neighborhood Hits	690	Shared Neighborhood Hits	78
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MTSS1_MOUSE
NC score	0.058806 (rank : 192)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	312	Target Neighborhood Hits	592	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PRRT3_MOUSE
NC score	0.058752 (rank : 193)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	312	Target Neighborhood Hits	162	Shared Neighborhood Hits	33
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SFPQ_HUMAN
NC score	0.058519 (rank : 194)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	312	Target Neighborhood Hits	986	Shared Neighborhood Hits	96
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SRRM1_HUMAN
NC score	0.058018 (rank : 195)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	312	Target Neighborhood Hits	690	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PRB3_HUMAN
NC score	0.057733 (rank : 196)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	312	Target Neighborhood Hits	318	Shared Neighborhood Hits	51
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

NFAC4_HUMAN
NC score	0.057699 (rank : 197)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	312	Target Neighborhood Hits	165	Shared Neighborhood Hits	27
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

CS007_HUMAN
NC score	0.057651 (rank : 198)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	312	Target Neighborhood Hits	401	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

SHAN1_HUMAN
NC score	0.057510 (rank : 199)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	312	Target Neighborhood Hits	1041	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MAP4_HUMAN
NC score	0.057201 (rank : 200)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	312	Target Neighborhood Hits	428	Shared Neighborhood Hits	70
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

BCAR1_HUMAN
NC score	0.057190 (rank : 201)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	312	Target Neighborhood Hits	554	Shared Neighborhood Hits	89
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GNAS1_MOUSE
NC score	0.057089 (rank : 202)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	312	Target Neighborhood Hits	651	Shared Neighborhood Hits	121
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

PICA_MOUSE
NC score	0.057045 (rank : 203)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	312	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

MAVS_HUMAN
NC score	0.056730 (rank : 204)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	312	Target Neighborhood Hits	271	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

OGFR_MOUSE
NC score	0.056724 (rank : 205)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	312	Target Neighborhood Hits	584	Shared Neighborhood Hits	86
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

NOLC1_HUMAN
NC score	0.056720 (rank : 206)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	312	Target Neighborhood Hits	452	Shared Neighborhood Hits	38
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

BAT3_MOUSE
NC score	0.056712 (rank : 207)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	312	Target Neighborhood Hits	518	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

SC24A_MOUSE
NC score	0.056282 (rank : 208)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	312	Target Neighborhood Hits	394	Shared Neighborhood Hits	89
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

WIRE_HUMAN
NC score	0.056278 (rank : 209)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	312	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

MUCDL_MOUSE
NC score	0.056275 (rank : 210)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	312	Target Neighborhood Hits	461	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MUC13_MOUSE
NC score	0.055968 (rank : 211)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	312	Target Neighborhood Hits	447	Shared Neighborhood Hits	51
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

DYN1_HUMAN
NC score	0.055815 (rank : 212)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	312	Target Neighborhood Hits	216	Shared Neighborhood Hits	47
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

SFPQ_MOUSE
NC score	0.055696 (rank : 213)	θ value	0.62314 (rank : 112)
Query Neighborhood Hits	312	Target Neighborhood Hits	958	Shared Neighborhood Hits	82
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PCQAP_MOUSE
NC score	0.055689 (rank : 214)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	312	Target Neighborhood Hits	506	Shared Neighborhood Hits	56
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

HCN4_HUMAN
NC score	0.055677 (rank : 215)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	312	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

MUC1_MOUSE
NC score	0.055633 (rank : 216)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	312	Target Neighborhood Hits	388	Shared Neighborhood Hits	60
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

GGN_HUMAN
NC score	0.055300 (rank : 217)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	312	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CT174_HUMAN
NC score	0.055123 (rank : 218)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	312	Target Neighborhood Hits	181	Shared Neighborhood Hits	44
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

EP15R_HUMAN
NC score	0.055113 (rank : 219)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	312	Target Neighborhood Hits	1083	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

PICAL_HUMAN
NC score	0.054903 (rank : 220)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	312	Target Neighborhood Hits	57	Shared Neighborhood Hits	11
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

TPO_MOUSE
NC score	0.054857 (rank : 221)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	312	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

WIRE_MOUSE
NC score	0.054786 (rank : 222)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	312	Target Neighborhood Hits	310	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MAP4_MOUSE
NC score	0.054760 (rank : 223)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	312	Target Neighborhood Hits	409	Shared Neighborhood Hits	67
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CPSF6_HUMAN
NC score	0.054472 (rank : 224)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	312	Target Neighborhood Hits	359	Shared Neighborhood Hits	67
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

DCP1A_HUMAN
NC score	0.054176 (rank : 225)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	312	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

WASF2_MOUSE
NC score	0.053858 (rank : 226)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	312	Target Neighborhood Hits	315	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BAG3_MOUSE
NC score	0.053849 (rank : 227)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	312	Target Neighborhood Hits	513	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

K0240_MOUSE
NC score	0.053768 (rank : 228)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	312	Target Neighborhood Hits	211	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

BASP_MOUSE
NC score	0.053648 (rank : 229)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	312	Target Neighborhood Hits	260	Shared Neighborhood Hits	36
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CPSF6_MOUSE
NC score	0.053605 (rank : 230)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	312	Target Neighborhood Hits	356	Shared Neighborhood Hits	64
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CD2_HUMAN
NC score	0.053536 (rank : 231)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	312	Target Neighborhood Hits	504	Shared Neighborhood Hits	76
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PDZD2_HUMAN
NC score	0.053363 (rank : 232)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	312	Target Neighborhood Hits	772	Shared Neighborhood Hits	115
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LAD1_MOUSE
NC score	0.053246 (rank : 233)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	312	Target Neighborhood Hits	391	Shared Neighborhood Hits	54
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

GPS2_HUMAN
NC score	0.053150 (rank : 234)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	312	Target Neighborhood Hits	459	Shared Neighborhood Hits	55
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

ANK2_HUMAN
NC score	0.052999 (rank : 235)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	312	Target Neighborhood Hits	1615	Shared Neighborhood Hits	158
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SEPT9_HUMAN
NC score	0.052981 (rank : 236)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	312	Target Neighborhood Hits	706	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

PGCA_HUMAN
NC score	0.052766 (rank : 237)	θ value	0.813845 (rank : 119)
Query Neighborhood Hits	312	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ATX2_MOUSE
NC score	0.052485 (rank : 238)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	312	Target Neighborhood Hits	445	Shared Neighborhood Hits	78
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

SYNJ2_HUMAN
NC score	0.052448 (rank : 239)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	312	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	O15056, Q5TA13, Q5TA16, Q5TA19, Q86XK0, Q8IZA8, Q9H226	Gene names	SYNJ2, KIAA0348
Domain Architecture	No domain graphic available
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

SPR1A_MOUSE
NC score	0.052234 (rank : 240)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	312	Target Neighborhood Hits	343	Shared Neighborhood Hits	69
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

RPC1_HUMAN
NC score	0.051993 (rank : 241)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	312	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O14802, Q8TCW5	Gene names	POLR3A
Domain Architecture
Description	DNA-directed RNA polymerase III largest subunit (EC 2.7.7.6) (RPC155) (RPC1).

DYN1_MOUSE
NC score	0.051942 (rank : 242)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	312	Target Neighborhood Hits	168	Shared Neighborhood Hits	31
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

MKL1_MOUSE
NC score	0.051736 (rank : 243)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	312	Target Neighborhood Hits	667	Shared Neighborhood Hits	119
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

TCOF_HUMAN
NC score	0.051650 (rank : 244)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	312	Target Neighborhood Hits	543	Shared Neighborhood Hits	54
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZN541_HUMAN
NC score	0.051563 (rank : 245)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	312	Target Neighborhood Hits	203	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

MAVS_MOUSE
NC score	0.051426 (rank : 246)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	312	Target Neighborhood Hits	170	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

TAU_HUMAN
NC score	0.051335 (rank : 247)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	312	Target Neighborhood Hits	448	Shared Neighborhood Hits	88
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MINT_HUMAN
NC score	0.051314 (rank : 248)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	312	Target Neighborhood Hits	1291	Shared Neighborhood Hits	120
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZN207_HUMAN
NC score	0.051117 (rank : 249)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	312	Target Neighborhood Hits	326	Shared Neighborhood Hits	44
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

BAZ2A_MOUSE
NC score	0.050758 (rank : 250)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	312	Target Neighborhood Hits	744	Shared Neighborhood Hits	113
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CD248_HUMAN
NC score	0.050696 (rank : 251)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	312	Target Neighborhood Hits	679	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

BORG5_HUMAN
NC score	0.050286 (rank : 252)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	312	Target Neighborhood Hits	135	Shared Neighborhood Hits	30
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

HCN4_MOUSE
NC score	0.050279 (rank : 253)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	312	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

SF3A2_MOUSE
NC score	0.050045 (rank : 254)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	312	Target Neighborhood Hits	247	Shared Neighborhood Hits	46
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

FMNL_HUMAN
NC score	0.050019 (rank : 255)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	312	Target Neighborhood Hits	529	Shared Neighborhood Hits	65
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

CJ026_MOUSE
NC score	0.048426 (rank : 256)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	312	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

TNC6B_HUMAN
NC score	0.047763 (rank : 257)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	312	Target Neighborhood Hits	256	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

PTN23_HUMAN
NC score	0.047302 (rank : 258)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	312	Target Neighborhood Hits	646	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

ATX2_HUMAN
NC score	0.047253 (rank : 259)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	312	Target Neighborhood Hits	375	Shared Neighborhood Hits	59
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

3BP1_HUMAN
NC score	0.046216 (rank : 260)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	312	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CSKI1_MOUSE
NC score	0.045838 (rank : 261)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	312	Target Neighborhood Hits	1031	Shared Neighborhood Hits	129
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RTN4_MOUSE
NC score	0.045656 (rank : 262)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	312	Target Neighborhood Hits	341	Shared Neighborhood Hits	47
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

DEN1A_MOUSE
NC score	0.044861 (rank : 263)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	312	Target Neighborhood Hits	178	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ATX3_HUMAN
NC score	0.044723 (rank : 264)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	312	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P54252, O15284, O15285, O15286, Q8N189, Q96TC3, Q96TC4, Q9H3N0	Gene names	ATXN3, ATX3, MJD, MJD1, SCA3
Domain Architecture
Description	Ataxin-3 (EC 3.4.22.-) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein).

NSD1_HUMAN
NC score	0.044722 (rank : 265)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	312	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TACC2_MOUSE
NC score	0.044703 (rank : 266)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	312	Target Neighborhood Hits	774	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WASL_HUMAN
NC score	0.044589 (rank : 267)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	312	Target Neighborhood Hits	312	Shared Neighborhood Hits	62
SwissProt Accessions	O00401, Q7Z746	Gene names	WASL
Domain Architecture
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

MEF2B_HUMAN
NC score	0.044020 (rank : 268)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	312	Target Neighborhood Hits	150	Shared Neighborhood Hits	41
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

CSPG3_HUMAN
NC score	0.043740 (rank : 269)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	312	Target Neighborhood Hits	676	Shared Neighborhood Hits	66
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ZIM10_MOUSE
NC score	0.043587 (rank : 270)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	312	Target Neighborhood Hits	430	Shared Neighborhood Hits	82
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

WASF2_HUMAN
NC score	0.042898 (rank : 271)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	312	Target Neighborhood Hits	280	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

BRD8_MOUSE
NC score	0.042751 (rank : 272)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	312	Target Neighborhood Hits	422	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CSKI2_HUMAN
NC score	0.041825 (rank : 273)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	312	Target Neighborhood Hits	747	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI1_HUMAN
NC score	0.041187 (rank : 274)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	312	Target Neighborhood Hits	997	Shared Neighborhood Hits	121
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SAPS1_MOUSE
NC score	0.040699 (rank : 275)	θ value	1.38821 (rank : 152)
Query Neighborhood Hits	312	Target Neighborhood Hits	144	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

NELFA_MOUSE
NC score	0.040500 (rank : 276)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	312	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

CO3A1_MOUSE
NC score	0.040085 (rank : 277)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	312	Target Neighborhood Hits	466	Shared Neighborhood Hits	69
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CUTL2_HUMAN
NC score	0.039814 (rank : 278)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	312	Target Neighborhood Hits	906	Shared Neighborhood Hits	68
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

NIPA_HUMAN
NC score	0.039664 (rank : 279)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	312	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q86WB0, Q75MF3, Q75MF4, Q8N330, Q96F75, Q9HA34, Q9NVX4, Q9P0R0	Gene names	ZC3HC1, NIPA
Domain Architecture	No domain graphic available
Description	Nuclear-interacting partner of ALK (Nuclear-interacting partner of anaplastic lymphoma kinase) (hNIPA) (Zinc finger C3HC-type protein 1).

CA106_HUMAN
NC score	0.039453 (rank : 280)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	312	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

FOXM1_HUMAN
NC score	0.039379 (rank : 281)	θ value	0.0148317 (rank : 38)
Query Neighborhood Hits	312	Target Neighborhood Hits	167	Shared Neighborhood Hits	28
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

DYN3_HUMAN
NC score	0.039254 (rank : 282)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	312	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

MAGC1_HUMAN
NC score	0.038965 (rank : 283)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	312	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

TGON1_MOUSE
NC score	0.038689 (rank : 284)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	312	Target Neighborhood Hits	243	Shared Neighborhood Hits	40
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

CUTL1_MOUSE
NC score	0.038282 (rank : 285)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	312	Target Neighborhood Hits	1620	Shared Neighborhood Hits	109
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

PGCA_MOUSE
NC score	0.038213 (rank : 286)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	312	Target Neighborhood Hits	643	Shared Neighborhood Hits	49
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CO1A1_HUMAN
NC score	0.037603 (rank : 287)	θ value	1.81305 (rank : 160)
Query Neighborhood Hits	312	Target Neighborhood Hits	475	Shared Neighborhood Hits	67
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SMCA4_HUMAN
NC score	0.037470 (rank : 288)	θ value	0.62314 (rank : 113)
Query Neighborhood Hits	312	Target Neighborhood Hits	597	Shared Neighborhood Hits	75
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

EP15_MOUSE
NC score	0.037285 (rank : 289)	θ value	0.62314 (rank : 109)
Query Neighborhood Hits	312	Target Neighborhood Hits	820	Shared Neighborhood Hits	20
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TTC15_HUMAN
NC score	0.037045 (rank : 290)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	312	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

CO1A2_HUMAN
NC score	0.036882 (rank : 291)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	312	Target Neighborhood Hits	329	Shared Neighborhood Hits	56
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

MILK2_HUMAN
NC score	0.036853 (rank : 292)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	312	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

PHAR2_HUMAN
NC score	0.036722 (rank : 293)	θ value	1.38821 (rank : 151)
Query Neighborhood Hits	312	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

EMID2_HUMAN
NC score	0.036610 (rank : 294)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	312	Target Neighborhood Hits	226	Shared Neighborhood Hits	42
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EMID2_MOUSE
NC score	0.036268 (rank : 295)	θ value	1.81305 (rank : 162)
Query Neighborhood Hits	312	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

CO1A1_MOUSE
NC score	0.036209 (rank : 296)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	312	Target Neighborhood Hits	457	Shared Neighborhood Hits	65
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

AFF1_MOUSE
NC score	0.035925 (rank : 297)	θ value	3.0926 (rank : 194)
Query Neighborhood Hits	312	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

DIAP1_MOUSE
NC score	0.035619 (rank : 298)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	312	Target Neighborhood Hits	839	Shared Neighborhood Hits	60
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

TAD3L_MOUSE
NC score	0.035367 (rank : 299)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	312	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAD3L_HUMAN
NC score	0.035231 (rank : 300)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	312	Target Neighborhood Hits	189	Shared Neighborhood Hits	5
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

HCFC1_HUMAN
NC score	0.034781 (rank : 301)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	312	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

USH1C_MOUSE
NC score	0.034671 (rank : 302)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	312	Target Neighborhood Hits	557	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

RTN1_HUMAN
NC score	0.033334 (rank : 303)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	312	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SAPS2_MOUSE
NC score	0.033041 (rank : 304)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	312	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R3Q2, Q9CXB7	Gene names	Saps2, Kiaa0685
Domain Architecture
Description	SAPS domain family member 2.

SKIV2_HUMAN
NC score	0.032846 (rank : 305)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	312	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

ZBP1_HUMAN
NC score	0.032586 (rank : 306)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	312	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H171, Q5JY39, Q9BYW4	Gene names	ZBP1, C20orf183, DLM1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

ITSN1_HUMAN
NC score	0.032259 (rank : 307)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	312	Target Neighborhood Hits	1757	Shared Neighborhood Hits	90
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PHLPP_HUMAN
NC score	0.032070 (rank : 308)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	312	Target Neighborhood Hits	604	Shared Neighborhood Hits	60
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

WNK2_HUMAN
NC score	0.031812 (rank : 309)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	312	Target Neighborhood Hits	1407	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RTN1_MOUSE
NC score	0.031464 (rank : 310)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	312	Target Neighborhood Hits	189	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

ATF7_HUMAN
NC score	0.031173 (rank : 311)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	312	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

GGA3_MOUSE
NC score	0.031082 (rank : 312)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	312	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

ATF7_MOUSE
NC score	0.031080 (rank : 313)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	312	Target Neighborhood Hits	286	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

GP152_HUMAN
NC score	0.030614 (rank : 314)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	312	Target Neighborhood Hits	636	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

PCX3_MOUSE
NC score	0.030243 (rank : 315)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	312	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

EMIL2_HUMAN
NC score	0.029446 (rank : 316)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	312	Target Neighborhood Hits	573	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

WHRN_MOUSE
NC score	0.029392 (rank : 317)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	312	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

JIP2_HUMAN
NC score	0.028448 (rank : 318)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	312	Target Neighborhood Hits	288	Shared Neighborhood Hits	49
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

OBSCN_HUMAN
NC score	0.028409 (rank : 319)	θ value	0.00134147 (rank : 19)
Query Neighborhood Hits	312	Target Neighborhood Hits	1931	Shared Neighborhood Hits	130
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ESX1L_HUMAN
NC score	0.027727 (rank : 320)	θ value	0.0113563 (rank : 36)
Query Neighborhood Hits	312	Target Neighborhood Hits	498	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

MYCN_HUMAN
NC score	0.027184 (rank : 321)	θ value	0.813845 (rank : 118)
Query Neighborhood Hits	312	Target Neighborhood Hits	127	Shared Neighborhood Hits	15
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYO15_MOUSE
NC score	0.026695 (rank : 322)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	312	Target Neighborhood Hits	467	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CF047_MOUSE
NC score	0.026672 (rank : 323)	θ value	1.81305 (rank : 158)
Query Neighborhood Hits	312	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

FBXL5_HUMAN
NC score	0.026589 (rank : 324)	θ value	1.81305 (rank : 163)
Query Neighborhood Hits	312	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKA1, Q8NHP3, Q9NXN2, Q9P0I0, Q9P0X5, Q9UJT7, Q9UKC8	Gene names	FBXL5, FBL4, FBL5, FLR1
Domain Architecture
Description	F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein).

GCNL2_HUMAN
NC score	0.026302 (rank : 325)	θ value	1.81305 (rank : 164)
Query Neighborhood Hits	312	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

PAR10_HUMAN
NC score	0.026081 (rank : 326)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	312	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q53GL7, Q8N2I0, Q8WV05, Q96CH7	Gene names	PARP10
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 10 (EC 2.4.2.30) (PARP-10).

CUTL2_MOUSE
NC score	0.026053 (rank : 327)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	312	Target Neighborhood Hits	771	Shared Neighborhood Hits	52
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HDAC4_HUMAN
NC score	0.025965 (rank : 328)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	312	Target Neighborhood Hits	390	Shared Neighborhood Hits	22
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

CO9A3_HUMAN
NC score	0.025788 (rank : 329)	θ value	1.38821 (rank : 140)
Query Neighborhood Hits	312	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

COFA1_MOUSE
NC score	0.025683 (rank : 330)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	312	Target Neighborhood Hits	305	Shared Neighborhood Hits	47
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

SOX18_HUMAN
NC score	0.025088 (rank : 331)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	312	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

UBQL4_MOUSE
NC score	0.024909 (rank : 332)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	312	Target Neighborhood Hits	99	Shared Neighborhood Hits	18
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

SMRC1_HUMAN
NC score	0.024667 (rank : 333)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	312	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

JPH4_MOUSE
NC score	0.024577 (rank : 334)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	312	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

IF4G3_MOUSE
NC score	0.024096 (rank : 335)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	312	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

UBQL4_HUMAN
NC score	0.024060 (rank : 336)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	312	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

RUSC2_HUMAN
NC score	0.023410 (rank : 337)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	312	Target Neighborhood Hits	205	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SALL3_HUMAN
NC score	0.023272 (rank : 338)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	312	Target Neighborhood Hits	1066	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZN414_HUMAN
NC score	0.023239 (rank : 339)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	312	Target Neighborhood Hits	548	Shared Neighborhood Hits	35
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

BAIP2_MOUSE
NC score	0.023222 (rank : 340)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	312	Target Neighborhood Hits	185	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BKX1, Q91V97, Q923V9, Q923W0	Gene names	Baiap2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor tyrosine kinase 53 kDa substrate).

NEST_HUMAN
NC score	0.023040 (rank : 341)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	312	Target Neighborhood Hits	1305	Shared Neighborhood Hits	69
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

DSPP_MOUSE
NC score	0.023006 (rank : 342)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	312	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

WNK4_HUMAN
NC score	0.021328 (rank : 343)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	312	Target Neighborhood Hits	1043	Shared Neighborhood Hits	72
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

AF17_HUMAN
NC score	0.020985 (rank : 344)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	312	Target Neighborhood Hits	230	Shared Neighborhood Hits	35
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

KCNH3_HUMAN
NC score	0.020754 (rank : 345)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	312	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

AMOL1_HUMAN
NC score	0.020652 (rank : 346)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	312	Target Neighborhood Hits	435	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

PME17_MOUSE
NC score	0.020642 (rank : 347)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	312	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

CSPG2_MOUSE
NC score	0.019969 (rank : 348)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	312	Target Neighborhood Hits	711	Shared Neighborhood Hits	45
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CTGE6_HUMAN
NC score	0.019817 (rank : 349)	θ value	1.81305 (rank : 161)
Query Neighborhood Hits	312	Target Neighborhood Hits	650	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

GNAS1_HUMAN
NC score	0.019702 (rank : 350)	θ value	1.81305 (rank : 165)
Query Neighborhood Hits	312	Target Neighborhood Hits	278	Shared Neighborhood Hits	50
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SYAP1_HUMAN
NC score	0.019653 (rank : 351)	θ value	3.0926 (rank : 206)
Query Neighborhood Hits	312	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q96A49, Q96C60, Q96JQ6, Q96T20	Gene names	SYAP1
Domain Architecture
Description	Synapse-associated protein 1.

ULK1_MOUSE
NC score	0.019645 (rank : 352)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	312	Target Neighborhood Hits	1214	Shared Neighborhood Hits	112
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

IRX3_HUMAN
NC score	0.019516 (rank : 353)	θ value	4.03905 (rank : 218)
Query Neighborhood Hits	312	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

THAP8_HUMAN
NC score	0.018626 (rank : 354)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	312	Target Neighborhood Hits	35	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

AF9_HUMAN
NC score	0.018323 (rank : 355)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	312	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MEGF9_HUMAN
NC score	0.018222 (rank : 356)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	312	Target Neighborhood Hits	557	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DDEF2_HUMAN
NC score	0.018003 (rank : 357)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	312	Target Neighborhood Hits	599	Shared Neighborhood Hits	44
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

PTPRN_MOUSE
NC score	0.017628 (rank : 358)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	312	Target Neighborhood Hits	240	Shared Neighborhood Hits	39
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

DVL2_HUMAN
NC score	0.017380 (rank : 359)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	312	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

IRX3_MOUSE
NC score	0.017068 (rank : 360)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	312	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

MYRIP_MOUSE
NC score	0.016892 (rank : 361)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	312	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MORC2_HUMAN
NC score	0.016748 (rank : 362)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	312	Target Neighborhood Hits	207	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SOX18_MOUSE
NC score	0.016623 (rank : 363)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	312	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

IRAK1_HUMAN
NC score	0.016468 (rank : 364)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	312	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

CAC1H_HUMAN
NC score	0.016445 (rank : 365)	θ value	3.0926 (rank : 195)
Query Neighborhood Hits	312	Target Neighborhood Hits	307	Shared Neighborhood Hits	46
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

ACK1_MOUSE
NC score	0.016239 (rank : 366)	θ value	0.163984 (rank : 67)
Query Neighborhood Hits	312	Target Neighborhood Hits	1080	Shared Neighborhood Hits	83
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

FETUB_MOUSE
NC score	0.015929 (rank : 367)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	312	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

MNAB_MOUSE
NC score	0.015735 (rank : 368)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	312	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RREB1_HUMAN
NC score	0.015635 (rank : 369)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	312	Target Neighborhood Hits	879	Shared Neighborhood Hits	49
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

RGS7_HUMAN
NC score	0.015397 (rank : 370)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	312	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	P49802, Q8TD66, Q8TD67, Q9UNU7, Q9Y6B9	Gene names	RGS7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

GATA5_HUMAN
NC score	0.014863 (rank : 371)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	312	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

FOXD2_MOUSE
NC score	0.014831 (rank : 372)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	312	Target Neighborhood Hits	130	Shared Neighborhood Hits	16
SwissProt Accessions	O35392	Gene names	Foxd2, Mf2
Domain Architecture
Description	Forkhead box protein D2 (Mesoderm/mesenchyme forkhead 2) (MF-2).

WFS1_HUMAN
NC score	0.014783 (rank : 373)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	312	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

PLXB1_MOUSE
NC score	0.014735 (rank : 374)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	312	Target Neighborhood Hits	259	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ACK1_HUMAN
NC score	0.014712 (rank : 375)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	312	Target Neighborhood Hits	1140	Shared Neighborhood Hits	91
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

NF2L3_MOUSE
NC score	0.014664 (rank : 376)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	312	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

WNK4_MOUSE
NC score	0.014629 (rank : 377)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	312	Target Neighborhood Hits	961	Shared Neighborhood Hits	50
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

PSD4_HUMAN
NC score	0.014543 (rank : 378)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	312	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

NUFP1_MOUSE
NC score	0.014529 (rank : 379)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	312	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

SOCS7_MOUSE
NC score	0.014348 (rank : 380)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	312	Target Neighborhood Hits	154	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

WWP1_MOUSE
NC score	0.013909 (rank : 381)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	312	Target Neighborhood Hits	138	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

RGS7_MOUSE
NC score	0.013692 (rank : 382)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	312	Target Neighborhood Hits	79	Shared Neighborhood Hits	5
SwissProt Accessions	O54829	Gene names	Rgs7
Domain Architecture
Description	Regulator of G-protein signaling 7 (RGS7).

IRAK1_MOUSE
NC score	0.013474 (rank : 383)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	312	Target Neighborhood Hits	784	Shared Neighborhood Hits	26
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

NFIA_MOUSE
NC score	0.013468 (rank : 384)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	312	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q02780, P70250, P70251, Q3UUZ2, Q61960, Q8VBT5, Q9R1G5	Gene names	Nfia
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

NFIA_HUMAN
NC score	0.013136 (rank : 385)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	312	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q12857, Q9H3X9, Q9P2A9	Gene names	NFIA, KIAA1439
Domain Architecture
Description	Nuclear factor 1 A-type (Nuclear factor 1/A) (NF1-A) (NFI-A) (NF-I/A) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

SHD_HUMAN
NC score	0.012947 (rank : 386)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	312	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q96IW2, Q96NC2	Gene names	SHD
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein D.

MYCL1_MOUSE
NC score	0.012920 (rank : 387)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	312	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

KLF17_HUMAN
NC score	0.012848 (rank : 388)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	312	Target Neighborhood Hits	882	Shared Neighborhood Hits	81
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

NUPL2_MOUSE
NC score	0.012794 (rank : 389)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	312	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

GATA5_MOUSE
NC score	0.012692 (rank : 390)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	312	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

NKX61_MOUSE
NC score	0.012475 (rank : 391)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	312	Target Neighborhood Hits	439	Shared Neighborhood Hits	29
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

PIBF1_HUMAN
NC score	0.012245 (rank : 392)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	312	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

X3CL1_MOUSE
NC score	0.012115 (rank : 393)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	312	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

RM43_MOUSE
NC score	0.012113 (rank : 394)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	312	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N89	Gene names	Mrpl43
Domain Architecture	No domain graphic available
Description	39S ribosomal protein L43, mitochondrial precursor (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a).

CENG1_HUMAN
NC score	0.012073 (rank : 395)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	312	Target Neighborhood Hits	544	Shared Neighborhood Hits	39
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

MK07_MOUSE
NC score	0.012052 (rank : 396)	θ value	0.813845 (rank : 117)
Query Neighborhood Hits	312	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

AP2A1_HUMAN
NC score	0.011421 (rank : 397)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	312	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

PAK7_HUMAN
NC score	0.010820 (rank : 398)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	312	Target Neighborhood Hits	875	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

RA6I1_HUMAN
NC score	0.010467 (rank : 399)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	312	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IQ26, Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1	Gene names	RAB6IP1, KIAA1091
Domain Architecture	No domain graphic available
Description	Rab6-interacting protein 1 (Rab6IP1).

CHFR_HUMAN
NC score	0.010455 (rank : 400)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	312	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TBX2_HUMAN
NC score	0.009807 (rank : 401)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	312	Target Neighborhood Hits	195	Shared Neighborhood Hits	30
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

PP16A_MOUSE
NC score	0.009689 (rank : 402)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	312	Target Neighborhood Hits	318	Shared Neighborhood Hits	10
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

BPAEA_MOUSE
NC score	0.009669 (rank : 403)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	312	Target Neighborhood Hits	1480	Shared Neighborhood Hits	36
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PAK7_MOUSE
NC score	0.009106 (rank : 404)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	312	Target Neighborhood Hits	875	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PSB4_HUMAN
NC score	0.009022 (rank : 405)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	312	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P28070, P31148, Q969L6	Gene names	PSMB4
Domain Architecture
Description	Proteasome subunit beta type 4 precursor (EC 3.4.25.1) (Proteasome beta chain) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome chain 3) (HSN3) (HsBPROS26).

MAST3_HUMAN
NC score	0.008580 (rank : 406)	θ value	1.81305 (rank : 166)
Query Neighborhood Hits	312	Target Neighborhood Hits	1128	Shared Neighborhood Hits	58
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

GP153_HUMAN
NC score	0.008488 (rank : 407)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	312	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

NOTC3_HUMAN
NC score	0.008193 (rank : 408)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	312	Target Neighborhood Hits	1062	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RGL2_MOUSE
NC score	0.008188 (rank : 409)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	312	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

M3K11_HUMAN
NC score	0.007968 (rank : 410)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	312	Target Neighborhood Hits	1136	Shared Neighborhood Hits	53
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

P53_MOUSE
NC score	0.007159 (rank : 411)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	312	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

BIRC7_HUMAN
NC score	0.007009 (rank : 412)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	312	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

FOXD4_MOUSE
NC score	0.006444 (rank : 413)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	312	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	Q60688, Q61573	Gene names	Foxd4, Fkh2, Fkhl9, Freac5
Domain Architecture
Description	Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead- related transcription factor 5) (FREAC-5) (Transcription factor FKH- 2).

CAPS2_HUMAN
NC score	0.005502 (rank : 414)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	312	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

BRSK1_HUMAN
NC score	0.005083 (rank : 415)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	312	Target Neighborhood Hits	942	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

ADEC1_MOUSE
NC score	0.004854 (rank : 416)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	312	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

BRSK2_HUMAN
NC score	0.003393 (rank : 417)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	312	Target Neighborhood Hits	897	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

MCR_HUMAN
NC score	0.002656 (rank : 418)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	312	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

PGBM_MOUSE
NC score	0.002480 (rank : 419)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	312	Target Neighborhood Hits	1073	Shared Neighborhood Hits	19
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MTF1_HUMAN
NC score	0.002095 (rank : 420)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	312	Target Neighborhood Hits	814	Shared Neighborhood Hits	37
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NEO1_MOUSE
NC score	0.001922 (rank : 421)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	312	Target Neighborhood Hits	523	Shared Neighborhood Hits	14
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

KIF9_MOUSE
NC score	0.001561 (rank : 422)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	312	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV04, O35070	Gene names	Kif9
Domain Architecture
Description	Kinesin-like protein KIF9.

MTF1_MOUSE
NC score	0.001071 (rank : 423)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	312	Target Neighborhood Hits	785	Shared Neighborhood Hits	29
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

HIC1_HUMAN
NC score	0.000647 (rank : 424)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	312	Target Neighborhood Hits	838	Shared Neighborhood Hits	30
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

SP4_MOUSE
NC score	-0.000306 (rank : 425)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	312	Target Neighborhood Hits	759	Shared Neighborhood Hits	18
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

ZN358_HUMAN
NC score	-0.000930 (rank : 426)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	312	Target Neighborhood Hits	840	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

HLAH_HUMAN
NC score	-0.001394 (rank : 427)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	312	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	P01893	Gene names	HLA-H, HLAH
Domain Architecture
Description	HLA class I histocompatibility antigen, alpha chain H precursor (HLA- AR) (HLA-12.4).

ZFP28_HUMAN
NC score	-0.001903 (rank : 428)	θ value	3.0926 (rank : 207)
Query Neighborhood Hits	312	Target Neighborhood Hits	843	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).