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Network neighborhood for query Sequence : DYN3_HUMAN

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DYN3_HUMAN
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DYN1_HUMAN
θ value	0 (rank : 1)	NC score	0.977281 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	216	Shared Neighborhood Hits	76
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_MOUSE
θ value	0 (rank : 2)	NC score	0.980064 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	168	Shared Neighborhood Hits	66
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN2_HUMAN
θ value	0 (rank : 3)	NC score	0.985646 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	112	Shared Neighborhood Hits	67
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
θ value	0 (rank : 4)	NC score	0.982752 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	104	Shared Neighborhood Hits	56
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DNM1L_HUMAN
θ value	1.0968e-122 (rank : 6)	NC score	0.941171 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

DNM1L_MOUSE
θ value	4.16784e-122 (rank : 7)	NC score	0.941301 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

MX1_HUMAN
θ value	3.47335e-60 (rank : 8)	NC score	0.859332 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_MOUSE
θ value	1.11734e-58 (rank : 9)	NC score	0.858062 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
θ value	6.13105e-57 (rank : 10)	NC score	0.857464 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
θ value	6.13105e-57 (rank : 11)	NC score	0.851947 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_HUMAN
θ value	1.86321e-21 (rank : 12)	NC score	0.679767 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_MOUSE
θ value	1.86321e-21 (rank : 13)	NC score	0.682724 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

CEL_HUMAN
θ value	2.61198e-07 (rank : 14)	NC score	0.081242 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

OGFR_HUMAN
θ value	9.29e-05 (rank : 15)	NC score	0.088422 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	1582	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC1_HUMAN
θ value	0.000602161 (rank : 16)	NC score	0.046854 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	975	Shared Neighborhood Hits	54
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CYH3_HUMAN
θ value	0.00102713 (rank : 17)	NC score	0.155719 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
θ value	0.00134147 (rank : 18)	NC score	0.158487 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
θ value	0.00134147 (rank : 19)	NC score	0.158289 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	176	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH2_HUMAN
θ value	0.00175202 (rank : 20)	NC score	0.149940 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	0.00175202 (rank : 21)	NC score	0.149911 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_MOUSE
θ value	0.00228821 (rank : 22)	NC score	0.152798 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

K2C4_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.010728 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	471	Shared Neighborhood Hits	14
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

SON_HUMAN
θ value	0.00869519 (rank : 24)	NC score	0.055008 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BCL9_HUMAN
θ value	0.0113563 (rank : 25)	NC score	0.076665 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	1008	Shared Neighborhood Hits	64
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CNKR1_HUMAN
θ value	0.0113563 (rank : 26)	NC score	0.173514 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	44
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PRRT3_HUMAN
θ value	0.0148317 (rank : 27)	NC score	0.081827 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CYH4_MOUSE
θ value	0.0330416 (rank : 28)	NC score	0.133188 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

MYO10_HUMAN
θ value	0.0330416 (rank : 29)	NC score	0.031200 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	920	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MAGE1_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.036709 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	1389	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PKHA6_HUMAN
θ value	0.0431538 (rank : 31)	NC score	0.126767 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	556	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CYH4_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.128241 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

RHG25_MOUSE
θ value	0.0736092 (rank : 33)	NC score	0.087477 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ANK2_HUMAN
θ value	0.0961366 (rank : 34)	NC score	0.021083 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CNKR2_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.145996 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	0.0961366 (rank : 36)	NC score	0.146103 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PKHA6_MOUSE
θ value	0.0961366 (rank : 37)	NC score	0.121248 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	591	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

LATS2_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.006275 (rank : 183)
Query Neighborhood Hits	158	Target Neighborhood Hits	884	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LPP_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.026317 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	775	Shared Neighborhood Hits	46
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PKHA5_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.115919 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLEK_HUMAN
θ value	0.163984 (rank : 41)	NC score	0.091786 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

HXB13_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.008561 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	384	Shared Neighborhood Hits	5
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

PER3_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.029620 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

EGR4_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.014386 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	939	Shared Neighborhood Hits	20
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

IF4B_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.060879 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

RNF25_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.036311 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

UGGG1_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.039367 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

GAB1_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.039951 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

IF4B_MOUSE
θ value	0.47712 (rank : 49)	NC score	0.055950 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PKHA1_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.083325 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	127	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RHG25_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.084879 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	550	Shared Neighborhood Hits	44
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SC24C_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.053421 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	662	Shared Neighborhood Hits	43
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

TARA_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.079718 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	1133	Shared Neighborhood Hits	70
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TS13_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.036356 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

ULK1_MOUSE
θ value	0.47712 (rank : 55)	NC score	0.006948 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	1214	Shared Neighborhood Hits	37
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ERBB2_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.001583 (rank : 191)
Query Neighborhood Hits	158	Target Neighborhood Hits	1073	Shared Neighborhood Hits	19
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

PO6F1_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.009707 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	581	Shared Neighborhood Hits	15
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

TARA_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.045613 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	1626	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.043829 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TTBK1_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.010704 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	1058	Shared Neighborhood Hits	42
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

UGGG1_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.030184 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

PKHA1_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.082547 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.079648 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

SAPS1_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.034454 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	704	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BCL9_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.065927 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	770	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CD2L7_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.006066 (rank : 185)
Query Neighborhood Hits	158	Target Neighborhood Hits	1275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

EPN3_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.039254 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

MLL3_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.038166 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	1644	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NFRKB_MOUSE
θ value	1.06291 (rank : 69)	NC score	0.026212 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

OSBP1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.027025 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

SOX30_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.014743 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

ARI1A_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.032395 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	787	Shared Neighborhood Hits	51
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BSN_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.040496 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CU086_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.049758 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P59089	Gene names	C21orf86
Domain Architecture	No domain graphic available
Description	Protein C21orf86.

JPH2_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.038581 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	639	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MTSS1_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.036185 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NACAM_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.043960 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	1866	Shared Neighborhood Hits	83
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NRX2A_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.026230 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	614	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.039469 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	481	Shared Neighborhood Hits	39
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PHLB1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.036412 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	1038	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PTPRN_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.006425 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

T22D4_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.031499 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	403	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

JADE2_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.013681 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PHLB1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.041090 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	678	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

REST_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.010130 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	1506	Shared Neighborhood Hits	35
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ROCK1_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.012335 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	2000	Shared Neighborhood Hits	36
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SEM6C_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.018322 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	352	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

TAU_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.026590 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	502	Shared Neighborhood Hits	36
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

UB7I1_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.015003 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

B4GN4_MOUSE
θ value	2.36792 (rank : 90)	NC score	0.012873 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

GCM1_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.014190 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

GNAS1_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.015870 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	651	Shared Neighborhood Hits	40
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GTSE1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.027618 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

MRIP_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.072961 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	578	Shared Neighborhood Hits	46
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.071382 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	569	Shared Neighborhood Hits	44
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MYH4_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.006871 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	1377	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

PKHA4_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.096481 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PPIP2_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.012771 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	308	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

ROCK1_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.012276 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	2126	Shared Neighborhood Hits	42
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TRIP6_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.015026 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

BAT3_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.039078 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	518	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CS007_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.034010 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	464	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DAB1_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.017185 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	219	Shared Neighborhood Hits	21
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

FYCO1_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.020184 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	1149	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

HERPU_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.015964 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q15011, O60644, Q96D92	Gene names	HERPUD1, KIAA0025, MIF1
Domain Architecture	No domain graphic available
Description	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1).

MEF2B_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.020814 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

MYO15_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.027143 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	671	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OAS3_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.010995 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

PDLI7_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.009209 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	547	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PK1L1_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.016638 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

RGS3_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.039484 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	1621	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RNF25_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.026505 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

TIAM1_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.023391 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ZIM10_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.027734 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	577	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

DDX23_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.002774 (rank : 188)
Query Neighborhood Hits	158	Target Neighborhood Hits	486	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

GP153_MOUSE
θ value	4.03905 (rank : 116)	NC score	0.008322 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

JPH2_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.021359 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

K1543_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.026316 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	435	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KCNH6_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.006760 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

SNIP_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.024894 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	313	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNIP_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.025961 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

EHMT2_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.007072 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	750	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EPN1_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.044339 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	240	Shared Neighborhood Hits	39
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

HCN3_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.006218 (rank : 184)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

MLL3_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.035624 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PI5PA_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.035710 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	749	Shared Neighborhood Hits	64
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RC3H1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.009402 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	433	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SC24A_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.053730 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	394	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SPEG_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.008964 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	1959	Shared Neighborhood Hits	70
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TIAM1_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.016641 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

VPS72_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.010473 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

APOL5_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.010439 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWW9, Q5TFL9, Q9UGW5	Gene names	APOL5
Domain Architecture
Description	Apolipoprotein-L5 (Apolipoprotein L-V) (ApoL-V).

ASPP1_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.015991 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	1244	Shared Neighborhood Hits	59
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATX7_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.029748 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CD248_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.010704 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	578	Shared Neighborhood Hits	35
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSKI1_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.026619 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	997	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LARP4_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.010209 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

MLL2_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.044025 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	1788	Shared Neighborhood Hits	98
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NCOR2_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.029857 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	870	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NPAS3_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.003930 (rank : 187)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NUMBL_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.017935 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

SRRM1_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.054166 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	966	Shared Neighborhood Hits	69
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TACC2_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.014243 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	856	Shared Neighborhood Hits	41
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

WNK2_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.010733 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	1407	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CAC1B_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.006594 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CE016_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.040986 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

FA47B_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.020672 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FLIP1_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.006781 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	1405	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.009713 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	1176	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GEMI5_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.002553 (rank : 189)
Query Neighborhood Hits	158	Target Neighborhood Hits	424	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

OBSCN_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.002531 (rank : 190)
Query Neighborhood Hits	158	Target Neighborhood Hits	1931	Shared Neighborhood Hits	53
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PELP1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.054430 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	709	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PICAL_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.011376 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

PICA_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.008565 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

PODXL_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.017738 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

REST_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.011845 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	1605	Shared Neighborhood Hits	35
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SSBP4_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.016904 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	753	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TNR3_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.004831 (rank : 186)
Query Neighborhood Hits	158	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

BIG1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.052616 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.053145 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

CK024_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.057284 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	408	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN032_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.061035 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.057618 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	233	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

GBF1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.058854 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.053426 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	674	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IQEC2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.056738 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	403	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.057042 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	417	Shared Neighborhood Hits	60
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.052446 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	274	Shared Neighborhood Hits	30
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MBD6_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.052633 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	349	Shared Neighborhood Hits	50
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MUC7_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.061377 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PKHA4_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.089957 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHB1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.067346 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PKHB1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.060608 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PRB3_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.063756 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.064002 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	330	Shared Neighborhood Hits	52
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.066455 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.072634 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.059932 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	460	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR13_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.053101 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PSD3_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.057783 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.056115 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

SF3A2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.054011 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	263	Shared Neighborhood Hits	43
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SF3A2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.055103 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	247	Shared Neighborhood Hits	47
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SMR3A_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.052313 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

TAF4_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.050629 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	687	Shared Neighborhood Hits	67
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WASIP_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.064047 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	458	Shared Neighborhood Hits	73
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.061281 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	392	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBP11_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051341 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	354	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.050346 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.051839 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	329	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.050278 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

Hits sorted by NC score

DYN3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

DYN2_HUMAN
NC score	0.985646 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	112	Shared Neighborhood Hits	67
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN2_MOUSE
NC score	0.982752 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	104	Shared Neighborhood Hits	56
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

DYN1_MOUSE
NC score	0.980064 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	168	Shared Neighborhood Hits	66
SwissProt Accessions	P39053, Q61358, Q61359, Q61360, Q8JZZ4, Q9CSY7, Q9QXX1	Gene names	Dnm1, Dnm
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DYN1_HUMAN
NC score	0.977281 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	216	Shared Neighborhood Hits	76
SwissProt Accessions	Q05193	Gene names	DNM1, DNM
Domain Architecture
Description	Dynamin-1 (EC 3.6.5.5).

DNM1L_MOUSE
NC score	0.941301 (rank : 6)	θ value	4.16784e-122 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1M6, Q8BNQ5, Q8BQ64, Q8CGD0, Q8K1A1	Gene names	Dnm1l, Drp1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-related protein 1) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple).

DNM1L_HUMAN
NC score	0.941171 (rank : 7)	θ value	1.0968e-122 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	O00429, O14541, O60709, Q7L6B3, Q8TBT7, Q9BWM1, Q9Y5J2	Gene names	DNM1L, DLP1, DRP1
Domain Architecture	No domain graphic available
Description	Dynamin-1-like protein (EC 3.6.5.5) (Dynamin-like protein) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-related protein 1) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV).

MX1_HUMAN
NC score	0.859332 (rank : 8)	θ value	3.47335e-60 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	P20591	Gene names	MX1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Interferon-regulated resistance GTP-binding protein MxA) (Interferon-induced protein p78) (IFI-78K).

MX2_MOUSE
NC score	0.858062 (rank : 9)	θ value	1.11734e-58 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVP9, Q922L4	Gene names	Mx2
Domain Architecture	No domain graphic available
Description	Interferon-induced GTP-binding protein Mx2.

MX1_MOUSE
NC score	0.857464 (rank : 10)	θ value	6.13105e-57 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P09922	Gene names	Mx1
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx1 (Influenza resistance protein).

MX2_HUMAN
NC score	0.851947 (rank : 11)	θ value	6.13105e-57 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P20592	Gene names	MX2
Domain Architecture
Description	Interferon-induced GTP-binding protein Mx2 (Interferon-regulated resistance GTP-binding protein MxB) (p78-related protein).

OPA1_MOUSE
NC score	0.682724 (rank : 12)	θ value	1.86321e-21 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	P58281, Q3ULA5, Q8BKU7, Q8BLL3, Q8BM08, Q8R3J7	Gene names	Opa1
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1 homolog) (Large GTP-binding protein) (LargeG) [Contains: Dynamin-like 120 kDa protein, form S1].

OPA1_HUMAN
NC score	0.679767 (rank : 13)	θ value	1.86321e-21 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	O60313	Gene names	OPA1, KIAA0567
Domain Architecture
Description	Dynamin-like 120 kDa protein, mitochondrial precursor (Optic atrophy protein 1) [Contains: Dynamin-like 120 kDa protein, form S1].

CNKR1_HUMAN
NC score	0.173514 (rank : 14)	θ value	0.0113563 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	44
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CYH1_HUMAN
NC score	0.158487 (rank : 15)	θ value	0.00134147 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH1_MOUSE
NC score	0.158289 (rank : 16)	θ value	0.00134147 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	176	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
NC score	0.155719 (rank : 17)	θ value	0.00102713 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
NC score	0.152798 (rank : 18)	θ value	0.00228821 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	34
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH2_HUMAN
NC score	0.149940 (rank : 19)	θ value	0.00175202 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	34
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.149911 (rank : 20)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CNKR2_MOUSE
NC score	0.146103 (rank : 21)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.145996 (rank : 22)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	197	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CYH4_MOUSE
NC score	0.133188 (rank : 23)	θ value	0.0330416 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.128241 (rank : 24)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

PKHA6_HUMAN
NC score	0.126767 (rank : 25)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	556	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.121248 (rank : 26)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	591	Shared Neighborhood Hits	61
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA5_HUMAN
NC score	0.115919 (rank : 27)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA4_HUMAN
NC score	0.096481 (rank : 28)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	283	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PLEK_HUMAN
NC score	0.091786 (rank : 29)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	110	Shared Neighborhood Hits	31
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHA4_MOUSE
NC score	0.089957 (rank : 30)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

OGFR_HUMAN
NC score	0.088422 (rank : 31)	θ value	9.29e-05 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	1582	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RHG25_MOUSE
NC score	0.087477 (rank : 32)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	492	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.084879 (rank : 33)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	550	Shared Neighborhood Hits	44
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

PKHA1_HUMAN
NC score	0.083325 (rank : 34)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	127	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.082547 (rank : 35)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	120	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PRRT3_HUMAN
NC score	0.081827 (rank : 36)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	998	Shared Neighborhood Hits	63
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CEL_HUMAN
NC score	0.081242 (rank : 37)	θ value	2.61198e-07 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

TARA_MOUSE
NC score	0.079718 (rank : 38)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	1133	Shared Neighborhood Hits	70
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PLEK_MOUSE
NC score	0.079648 (rank : 39)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	109	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

BCL9_HUMAN
NC score	0.076665 (rank : 40)	θ value	0.0113563 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	1008	Shared Neighborhood Hits	64
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MRIP_HUMAN
NC score	0.072961 (rank : 41)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	578	Shared Neighborhood Hits	46
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PRP2_MOUSE
NC score	0.072634 (rank : 42)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

MRIP_MOUSE
NC score	0.071382 (rank : 43)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	569	Shared Neighborhood Hits	44
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

PKHB1_HUMAN
NC score	0.067346 (rank : 44)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UF11, Q9UBF5, Q9UI37, Q9UI44	Gene names	PLEKHB1, KPL1, PHR1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PRP1_HUMAN
NC score	0.066455 (rank : 45)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	385	Shared Neighborhood Hits	61
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

BCL9_MOUSE
NC score	0.065927 (rank : 46)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	770	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

WASIP_HUMAN
NC score	0.064047 (rank : 47)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	158	Target Neighborhood Hits	458	Shared Neighborhood Hits	73
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

PRB4S_HUMAN
NC score	0.064002 (rank : 48)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	330	Shared Neighborhood Hits	52
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRB3_HUMAN
NC score	0.063756 (rank : 49)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

MUC7_HUMAN
NC score	0.061377 (rank : 50)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	538	Shared Neighborhood Hits	59
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

WASIP_MOUSE
NC score	0.061281 (rank : 51)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	158	Target Neighborhood Hits	392	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CN032_HUMAN
NC score	0.061035 (rank : 52)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	267	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

IF4B_HUMAN
NC score	0.060879 (rank : 53)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	417	Shared Neighborhood Hits	21
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PKHB1_MOUSE
NC score	0.060608 (rank : 54)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE9, Q9QYB3, Q9QYB4, Q9QYD2, Q9QYD3	Gene names	Plekhb1, Phr1
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain-containing protein in retina 1) (PHRET1).

PRR12_HUMAN
NC score	0.059932 (rank : 55)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	460	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

GBF1_HUMAN
NC score	0.058854 (rank : 56)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

PSD3_HUMAN
NC score	0.057783 (rank : 57)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CN032_MOUSE
NC score	0.057618 (rank : 58)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	233	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CK024_HUMAN
NC score	0.057284 (rank : 59)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	408	Shared Neighborhood Hits	36
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

IQEC2_MOUSE
NC score	0.057042 (rank : 60)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	417	Shared Neighborhood Hits	60
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.056738 (rank : 61)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	403	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

PSD4_HUMAN
NC score	0.056115 (rank : 62)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

IF4B_MOUSE
NC score	0.055950 (rank : 63)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SF3A2_MOUSE
NC score	0.055103 (rank : 64)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	158	Target Neighborhood Hits	247	Shared Neighborhood Hits	47
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SON_HUMAN
NC score	0.055008 (rank : 65)	θ value	0.00869519 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	1568	Shared Neighborhood Hits	73
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PELP1_MOUSE
NC score	0.054430 (rank : 66)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	709	Shared Neighborhood Hits	62
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SRRM1_MOUSE
NC score	0.054166 (rank : 67)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	966	Shared Neighborhood Hits	69
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SF3A2_HUMAN
NC score	0.054011 (rank : 68)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	263	Shared Neighborhood Hits	43
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SC24A_MOUSE
NC score	0.053730 (rank : 69)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	394	Shared Neighborhood Hits	36
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

GSCR1_HUMAN
NC score	0.053426 (rank : 70)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	674	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SC24C_HUMAN
NC score	0.053421 (rank : 71)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	662	Shared Neighborhood Hits	43
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BIG2_HUMAN
NC score	0.053145 (rank : 72)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

PRR13_HUMAN
NC score	0.053101 (rank : 73)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

MBD6_HUMAN
NC score	0.052633 (rank : 74)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	349	Shared Neighborhood Hits	50
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

BIG1_HUMAN
NC score	0.052616 (rank : 75)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

IQEC3_MOUSE
NC score	0.052446 (rank : 76)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	274	Shared Neighborhood Hits	30
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

SMR3A_HUMAN
NC score	0.052313 (rank : 77)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	158	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

WIRE_HUMAN
NC score	0.051839 (rank : 78)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	158	Target Neighborhood Hits	329	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WBP11_HUMAN
NC score	0.051341 (rank : 79)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	158	Target Neighborhood Hits	354	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

TAF4_HUMAN
NC score	0.050629 (rank : 80)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	158	Target Neighborhood Hits	687	Shared Neighborhood Hits	67
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

WBP11_MOUSE
NC score	0.050346 (rank : 81)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	158	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_MOUSE
NC score	0.050278 (rank : 82)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	158	Target Neighborhood Hits	310	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CU086_HUMAN
NC score	0.049758 (rank : 83)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	7	Shared Neighborhood Hits	5
SwissProt Accessions	P59089	Gene names	C21orf86
Domain Architecture	No domain graphic available
Description	Protein C21orf86.

MUC1_HUMAN
NC score	0.046854 (rank : 84)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	975	Shared Neighborhood Hits	54
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TARA_HUMAN
NC score	0.045613 (rank : 85)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	1626	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

EPN1_MOUSE
NC score	0.044339 (rank : 86)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	240	Shared Neighborhood Hits	39
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

MLL2_HUMAN
NC score	0.044025 (rank : 87)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	1788	Shared Neighborhood Hits	98
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NACAM_MOUSE
NC score	0.043960 (rank : 88)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	1866	Shared Neighborhood Hits	83
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TARSH_HUMAN
NC score	0.043829 (rank : 89)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

PHLB1_MOUSE
NC score	0.041090 (rank : 90)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	678	Shared Neighborhood Hits	65
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CE016_HUMAN
NC score	0.040986 (rank : 91)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

BSN_MOUSE
NC score	0.040496 (rank : 92)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GAB1_MOUSE
NC score	0.039951 (rank : 93)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

RGS3_MOUSE
NC score	0.039484 (rank : 94)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	1621	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NRX2B_HUMAN
NC score	0.039469 (rank : 95)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	481	Shared Neighborhood Hits	39
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

UGGG1_MOUSE
NC score	0.039367 (rank : 96)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P5E4, Q6NV70	Gene names	Ugcgl1, Gt, Uggt, Ugt1, Ugtr
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase).

EPN3_MOUSE
NC score	0.039254 (rank : 97)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	312	Shared Neighborhood Hits	32
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

BAT3_MOUSE
NC score	0.039078 (rank : 98)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	518	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

JPH2_HUMAN
NC score	0.038581 (rank : 99)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	639	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MLL3_HUMAN
NC score	0.038166 (rank : 100)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	1644	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAGE1_HUMAN
NC score	0.036709 (rank : 101)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	1389	Shared Neighborhood Hits	75
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PHLB1_HUMAN
NC score	0.036412 (rank : 102)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	1038	Shared Neighborhood Hits	72
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

TS13_MOUSE
NC score	0.036356 (rank : 103)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q01755	Gene names	Tcp11
Domain Architecture
Description	Testis-specific protein PBS13.

RNF25_HUMAN
NC score	0.036311 (rank : 104)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

MTSS1_MOUSE
NC score	0.036185 (rank : 105)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PI5PA_HUMAN
NC score	0.035710 (rank : 106)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	749	Shared Neighborhood Hits	64
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

MLL3_MOUSE
NC score	0.035624 (rank : 107)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SAPS1_HUMAN
NC score	0.034454 (rank : 108)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	704	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CS007_MOUSE
NC score	0.034010 (rank : 109)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	464	Shared Neighborhood Hits	45
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

ARI1A_HUMAN
NC score	0.032395 (rank : 110)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	787	Shared Neighborhood Hits	51
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

T22D4_HUMAN
NC score	0.031499 (rank : 111)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	403	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

MYO10_HUMAN
NC score	0.031200 (rank : 112)	θ value	0.0330416 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	920	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

UGGG1_HUMAN
NC score	0.030184 (rank : 113)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NYU2, Q8IW30, Q9H8I4	Gene names	UGCGL1, GT, UGGT, UGT1, UGTR
Domain Architecture	No domain graphic available
Description	UDP-glucose:glycoprotein glucosyltransferase 1 precursor (EC 2.4.1.-) (UDP-glucose ceramide glucosyltransferase-like 1) (UDP-- Glc:glycoprotein glucosyltransferase) (HUGT1).

NCOR2_HUMAN
NC score	0.029857 (rank : 114)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	870	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ATX7_MOUSE
NC score	0.029748 (rank : 115)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	328	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

PER3_HUMAN
NC score	0.029620 (rank : 116)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	479	Shared Neighborhood Hits	35
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

ZIM10_HUMAN
NC score	0.027734 (rank : 117)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	577	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

GTSE1_HUMAN
NC score	0.027618 (rank : 118)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

MYO15_HUMAN
NC score	0.027143 (rank : 119)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	671	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OSBP1_HUMAN
NC score	0.027025 (rank : 120)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	180	Shared Neighborhood Hits	28
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CSKI1_HUMAN
NC score	0.026619 (rank : 121)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	997	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TAU_MOUSE
NC score	0.026590 (rank : 122)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	502	Shared Neighborhood Hits	36
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RNF25_MOUSE
NC score	0.026505 (rank : 123)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

LPP_HUMAN
NC score	0.026317 (rank : 124)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	775	Shared Neighborhood Hits	46
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

K1543_HUMAN
NC score	0.026316 (rank : 125)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	435	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NRX2A_HUMAN
NC score	0.026230 (rank : 126)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	614	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NFRKB_MOUSE
NC score	0.026212 (rank : 127)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	393	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

SNIP_MOUSE
NC score	0.025961 (rank : 128)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	319	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNIP_HUMAN
NC score	0.024894 (rank : 129)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	313	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TIAM1_HUMAN
NC score	0.023391 (rank : 130)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

JPH2_MOUSE
NC score	0.021359 (rank : 131)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ANK2_HUMAN
NC score	0.021083 (rank : 132)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	1615	Shared Neighborhood Hits	67
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MEF2B_MOUSE
NC score	0.020814 (rank : 133)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

FA47B_HUMAN
NC score	0.020672 (rank : 134)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FYCO1_HUMAN
NC score	0.020184 (rank : 135)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	1149	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

SEM6C_MOUSE
NC score	0.018322 (rank : 136)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	352	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

NUMBL_HUMAN
NC score	0.017935 (rank : 137)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	394	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PODXL_HUMAN
NC score	0.017738 (rank : 138)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

DAB1_HUMAN
NC score	0.017185 (rank : 139)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	219	Shared Neighborhood Hits	21
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

SSBP4_HUMAN
NC score	0.016904 (rank : 140)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	753	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TIAM1_MOUSE
NC score	0.016641 (rank : 141)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	205	Shared Neighborhood Hits	17
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

PK1L1_HUMAN
NC score	0.016638 (rank : 142)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

ASPP1_MOUSE
NC score	0.015991 (rank : 143)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	1244	Shared Neighborhood Hits	59
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

HERPU_HUMAN
NC score	0.015964 (rank : 144)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q15011, O60644, Q96D92	Gene names	HERPUD1, KIAA0025, MIF1
Domain Architecture	No domain graphic available
Description	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1).

GNAS1_MOUSE
NC score	0.015870 (rank : 145)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	651	Shared Neighborhood Hits	40
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TRIP6_HUMAN
NC score	0.015026 (rank : 146)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

UB7I1_MOUSE
NC score	0.015003 (rank : 147)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

SOX30_HUMAN
NC score	0.014743 (rank : 148)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

EGR4_HUMAN
NC score	0.014386 (rank : 149)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	939	Shared Neighborhood Hits	20
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

TACC2_HUMAN
NC score	0.014243 (rank : 150)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	856	Shared Neighborhood Hits	41
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

GCM1_MOUSE
NC score	0.014190 (rank : 151)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

JADE2_MOUSE
NC score	0.013681 (rank : 152)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

B4GN4_MOUSE
NC score	0.012873 (rank : 153)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

PPIP2_MOUSE
NC score	0.012771 (rank : 154)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	308	Shared Neighborhood Hits	9
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

ROCK1_HUMAN
NC score	0.012335 (rank : 155)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	2000	Shared Neighborhood Hits	36
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
NC score	0.012276 (rank : 156)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	2126	Shared Neighborhood Hits	42
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

REST_HUMAN
NC score	0.011845 (rank : 157)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	1605	Shared Neighborhood Hits	35
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

PICAL_HUMAN
NC score	0.011376 (rank : 158)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

OAS3_HUMAN
NC score	0.010995 (rank : 159)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

WNK2_HUMAN
NC score	0.010733 (rank : 160)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	1407	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

K2C4_HUMAN
NC score	0.010728 (rank : 161)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	471	Shared Neighborhood Hits	14
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

CD248_MOUSE
NC score	0.010704 (rank : 162)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	578	Shared Neighborhood Hits	35
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TTBK1_HUMAN
NC score	0.010704 (rank : 163)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	1058	Shared Neighborhood Hits	42
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

VPS72_HUMAN
NC score	0.010473 (rank : 164)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	274	Shared Neighborhood Hits	8
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

APOL5_HUMAN
NC score	0.010439 (rank : 165)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWW9, Q5TFL9, Q9UGW5	Gene names	APOL5
Domain Architecture
Description	Apolipoprotein-L5 (Apolipoprotein L-V) (ApoL-V).

LARP4_MOUSE
NC score	0.010209 (rank : 166)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BWW4, Q3UR69	Gene names	Larp4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

REST_MOUSE
NC score	0.010130 (rank : 167)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	1506	Shared Neighborhood Hits	35
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

FLIP1_MOUSE
NC score	0.009713 (rank : 168)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	1176	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

PO6F1_MOUSE
NC score	0.009707 (rank : 169)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	581	Shared Neighborhood Hits	15
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

RC3H1_HUMAN
NC score	0.009402 (rank : 170)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	433	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

PDLI7_HUMAN
NC score	0.009209 (rank : 171)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	547	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

SPEG_MOUSE
NC score	0.008964 (rank : 172)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	1959	Shared Neighborhood Hits	70
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PICA_MOUSE
NC score	0.008565 (rank : 173)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

HXB13_MOUSE
NC score	0.008561 (rank : 174)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	384	Shared Neighborhood Hits	5
SwissProt Accessions	P70321, Q80Y12	Gene names	Hoxb13
Domain Architecture
Description	Homeobox protein Hox-B13.

GP153_MOUSE
NC score	0.008322 (rank : 175)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

EHMT2_MOUSE
NC score	0.007072 (rank : 176)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	750	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ULK1_MOUSE
NC score	0.006948 (rank : 177)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	1214	Shared Neighborhood Hits	37
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

MYH4_HUMAN
NC score	0.006871 (rank : 178)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	1377	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

FLIP1_HUMAN
NC score	0.006781 (rank : 179)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	1405	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

KCNH6_HUMAN
NC score	0.006760 (rank : 180)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

CAC1B_MOUSE
NC score	0.006594 (rank : 181)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	351	Shared Neighborhood Hits	28
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PTPRN_MOUSE
NC score	0.006425 (rank : 182)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	240	Shared Neighborhood Hits	13
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

LATS2_HUMAN
NC score	0.006275 (rank : 183)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	884	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

HCN3_HUMAN
NC score	0.006218 (rank : 184)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1Z3, Q4VX12, Q8N6W6, Q9BWQ2	Gene names	HCN3, KIAA1535
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.

CD2L7_HUMAN
NC score	0.006066 (rank : 185)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	1275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

TNR3_HUMAN
NC score	0.004831 (rank : 186)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

NPAS3_MOUSE
NC score	0.003930 (rank : 187)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

DDX23_HUMAN
NC score	0.002774 (rank : 188)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	486	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

GEMI5_MOUSE
NC score	0.002553 (rank : 189)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	424	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

OBSCN_HUMAN
NC score	0.002531 (rank : 190)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	1931	Shared Neighborhood Hits	53
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ERBB2_HUMAN
NC score	0.001583 (rank : 191)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	1073	Shared Neighborhood Hits	19
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).