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Network neighborhood for query Sequence : OAS3_HUMAN

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OAS3_HUMAN
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OAS3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

OAS2_HUMAN
θ value	2.18449e-163 (rank : 2)	NC score	0.967095 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P29728, Q86XX8	Gene names	OAS2
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 2 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 2) (2-5A synthetase 2) (p69 OAS / p71 OAS) (p69OAS / p71OAS).

OAS1_HUMAN
θ value	2.22025e-107 (rank : 3)	NC score	0.957894 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P00973, P04820, P29080, P29081, P78485, P78486, Q16700, Q16701, Q96J61	Gene names	OAS1, OIAS
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 1 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 1) (2-5A synthetase 1) (p46/p42 OAS) (E18/E16).

OAS1A_MOUSE
θ value	1.54472e-92 (rank : 4)	NC score	0.953654 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P11928, Q64440	Gene names	Oas1a, Oias1
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 1A (EC 2.7.7.-) ((2-5')oligo(A) synthetase 1A) (2-5A synthetase 1A) (p42 OAS).

OASL2_MOUSE
θ value	2.82823e-78 (rank : 5)	NC score	0.928938 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2F2	Gene names	Oasl2
Domain Architecture
Description	54 kDa 2'-5'-oligoadenylate synthetase-like protein 2 (EC 2.7.7.-) (p54 OASL) (p54OASL) (M1204).

OASL_HUMAN
θ value	4.37348e-71 (rank : 6)	NC score	0.901551 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q15646, O75686, Q9Y6K6, Q9Y6K7	Gene names	OASL, TRIP14
Domain Architecture
Description	59 kDa 2'-5'-oligoadenylate synthetase-like protein (p59 OASL) (p59OASL) (Thyroid receptor-interacting protein 14) (TRIP14).

RBM12_MOUSE
θ value	0.00869519 (rank : 7)	NC score	0.054191 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

MYT1_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.041355 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	475	Shared Neighborhood Hits	4
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

SMAL1_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.030503 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

TB182_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.048786 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

EXTL3_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.025737 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

HXD13_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.012165 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	332	Shared Neighborhood Hits	5
SwissProt Accessions	P35453	Gene names	HOXD13, HOX4I
Domain Architecture
Description	Homeobox protein Hox-D13 (Hox-4I).

PCQAP_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.026231 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	506	Shared Neighborhood Hits	8
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MOD5_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.029138 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UN9, Q9D1H5	Gene names	Trit1, Ipt
Domain Architecture
Description	tRNA isopentenyltransferase, mitochondrial precursor (EC 2.5.1.8) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPTase) (IPPT).

MYT1_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.033044 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

PHLPP_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.008414 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	604	Shared Neighborhood Hits	7
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

UBP36_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.012073 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

DYN3_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.010995 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

RX_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.006186 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

CKLF2_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.024872 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAZ6, Q8N7E5	Gene names	CMTM2, CKLFSF2
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 2 (Chemokine- like factor superfamily member 2).

HD_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.016435 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

LTBP3_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.004175 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	475	Shared Neighborhood Hits	2
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

VMDL1_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.012292 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

ANX11_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.006797 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

BRCA2_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.014126 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CN004_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.017279 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

DDX11_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.013015 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

MORC2_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.010805 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SRBS1_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.009638 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	396	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CT055_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.017929 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

DOT1L_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.014081 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FOXGB_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.004638 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

IGHG4_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.004779 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P01861	Gene names	IGHG4
Domain Architecture
Description	Ig gamma-4 chain C region.

MYT1L_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.025607 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

PCLO_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.008784 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	2046	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.009502 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	2275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PMS1_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.027918 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

TBX3_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.005799 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

ADCY1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.004463 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q08828, Q75MI1	Gene names	ADCY1
Domain Architecture	No domain graphic available
Description	Adenylate cyclase type 1 (EC 4.6.1.1) (Adenylate cyclase type I) (ATP pyrophosphate-lyase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase).

CCKN_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.018001 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P09240	Gene names	Cck
Domain Architecture
Description	Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 33 (CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].

DBND2_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.015037 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

EGR2_MOUSE
θ value	8.99809 (rank : 42)	NC score	-0.000769 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	745	Shared Neighborhood Hits	3
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).

EHMT2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.002072 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EXTL3_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.018639 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

F113A_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.012615 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1Q7, Q5JUA5, Q5JUA6, Q6PK19, Q86WF5, Q96CG7, Q9H1Q6, Q9H6D1	Gene names	FAM113A, C20orf81
Domain Architecture	No domain graphic available
Description	Protein FAM113A (Sarcoma antigen NY-SAR-23).

MTP_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.011290 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O08601	Gene names	Mttp, Mtp
Domain Architecture
Description	Microsomal triglyceride transfer protein large subunit precursor.

SSBP4_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.009686 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

WNK1_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.000406 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	1158	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

WNK2_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.000841 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	1407	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

Hits sorted by NC score

OAS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

OAS2_HUMAN
NC score	0.967095 (rank : 2)	θ value	2.18449e-163 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	P29728, Q86XX8	Gene names	OAS2
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 2 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 2) (2-5A synthetase 2) (p69 OAS / p71 OAS) (p69OAS / p71OAS).

OAS1_HUMAN
NC score	0.957894 (rank : 3)	θ value	2.22025e-107 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P00973, P04820, P29080, P29081, P78485, P78486, Q16700, Q16701, Q96J61	Gene names	OAS1, OIAS
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 1 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 1) (2-5A synthetase 1) (p46/p42 OAS) (E18/E16).

OAS1A_MOUSE
NC score	0.953654 (rank : 4)	θ value	1.54472e-92 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P11928, Q64440	Gene names	Oas1a, Oias1
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 1A (EC 2.7.7.-) ((2-5')oligo(A) synthetase 1A) (2-5A synthetase 1A) (p42 OAS).

OASL2_MOUSE
NC score	0.928938 (rank : 5)	θ value	2.82823e-78 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2F2	Gene names	Oasl2
Domain Architecture
Description	54 kDa 2'-5'-oligoadenylate synthetase-like protein 2 (EC 2.7.7.-) (p54 OASL) (p54OASL) (M1204).

OASL_HUMAN
NC score	0.901551 (rank : 6)	θ value	4.37348e-71 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q15646, O75686, Q9Y6K6, Q9Y6K7	Gene names	OASL, TRIP14
Domain Architecture
Description	59 kDa 2'-5'-oligoadenylate synthetase-like protein (p59 OASL) (p59OASL) (Thyroid receptor-interacting protein 14) (TRIP14).

RBM12_MOUSE
NC score	0.054191 (rank : 7)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

TB182_HUMAN
NC score	0.048786 (rank : 8)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MYT1_HUMAN
NC score	0.041355 (rank : 9)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	475	Shared Neighborhood Hits	4
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYT1_MOUSE
NC score	0.033044 (rank : 10)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

SMAL1_HUMAN
NC score	0.030503 (rank : 11)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

MOD5_MOUSE
NC score	0.029138 (rank : 12)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UN9, Q9D1H5	Gene names	Trit1, Ipt
Domain Architecture
Description	tRNA isopentenyltransferase, mitochondrial precursor (EC 2.5.1.8) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPTase) (IPPT).

PMS1_HUMAN
NC score	0.027918 (rank : 13)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

PCQAP_MOUSE
NC score	0.026231 (rank : 14)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	506	Shared Neighborhood Hits	8
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

EXTL3_MOUSE
NC score	0.025737 (rank : 15)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

MYT1L_HUMAN
NC score	0.025607 (rank : 16)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	471	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

CKLF2_HUMAN
NC score	0.024872 (rank : 17)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAZ6, Q8N7E5	Gene names	CMTM2, CKLFSF2
Domain Architecture
Description	CKLF-like MARVEL transmembrane domain-containing protein 2 (Chemokine- like factor superfamily member 2).

EXTL3_HUMAN
NC score	0.018639 (rank : 18)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

CCKN_MOUSE
NC score	0.018001 (rank : 19)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P09240	Gene names	Cck
Domain Architecture
Description	Cholecystokinins precursor (CCK) [Contains: Cholecystokinin 33 (CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].

CT055_HUMAN
NC score	0.017929 (rank : 20)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQ89	Gene names	C20orf55
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf55.

CN004_MOUSE
NC score	0.017279 (rank : 21)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

HD_MOUSE
NC score	0.016435 (rank : 22)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

DBND2_HUMAN
NC score	0.015037 (rank : 23)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

BRCA2_HUMAN
NC score	0.014126 (rank : 24)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

DOT1L_HUMAN
NC score	0.014081 (rank : 25)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DDX11_HUMAN
NC score	0.013015 (rank : 26)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q96FC9, Q13333, Q86VQ4, Q86W62, Q92498, Q92770, Q92998, Q92999	Gene names	DDX11, CHL1, CHLR1, KRG2
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX11 (EC 3.6.1.-) (DEAD/H box protein 11) (CHL1 homolog) (Keratinocyte growth factor-regulated gene 2 protein) (KRG-2).

F113A_HUMAN
NC score	0.012615 (rank : 27)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1Q7, Q5JUA5, Q5JUA6, Q6PK19, Q86WF5, Q96CG7, Q9H1Q6, Q9H6D1	Gene names	FAM113A, C20orf81
Domain Architecture	No domain graphic available
Description	Protein FAM113A (Sarcoma antigen NY-SAR-23).

VMDL1_MOUSE
NC score	0.012292 (rank : 28)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

HXD13_HUMAN
NC score	0.012165 (rank : 29)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	332	Shared Neighborhood Hits	5
SwissProt Accessions	P35453	Gene names	HOXD13, HOX4I
Domain Architecture
Description	Homeobox protein Hox-D13 (Hox-4I).

UBP36_HUMAN
NC score	0.012073 (rank : 30)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

MTP_MOUSE
NC score	0.011290 (rank : 31)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O08601	Gene names	Mttp, Mtp
Domain Architecture
Description	Microsomal triglyceride transfer protein large subunit precursor.

DYN3_HUMAN
NC score	0.010995 (rank : 32)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

MORC2_HUMAN
NC score	0.010805 (rank : 33)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SSBP4_HUMAN
NC score	0.009686 (rank : 34)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	753	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SRBS1_HUMAN
NC score	0.009638 (rank : 35)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	396	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PCLO_MOUSE
NC score	0.009502 (rank : 36)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	2275	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCLO_HUMAN
NC score	0.008784 (rank : 37)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	2046	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHLPP_HUMAN
NC score	0.008414 (rank : 38)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	604	Shared Neighborhood Hits	7
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

ANX11_MOUSE
NC score	0.006797 (rank : 39)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

RX_HUMAN
NC score	0.006186 (rank : 40)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	423	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TBX3_HUMAN
NC score	0.005799 (rank : 41)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	O15119, Q8TB20, Q9UKF8	Gene names	TBX3
Domain Architecture
Description	T-box transcription factor TBX3 (T-box protein 3).

IGHG4_HUMAN
NC score	0.004779 (rank : 42)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	223	Shared Neighborhood Hits	2
SwissProt Accessions	P01861	Gene names	IGHG4
Domain Architecture
Description	Ig gamma-4 chain C region.

FOXGB_HUMAN
NC score	0.004638 (rank : 43)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

ADCY1_HUMAN
NC score	0.004463 (rank : 44)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q08828, Q75MI1	Gene names	ADCY1
Domain Architecture	No domain graphic available
Description	Adenylate cyclase type 1 (EC 4.6.1.1) (Adenylate cyclase type I) (ATP pyrophosphate-lyase 1) (Ca(2+)/calmodulin-activated adenylyl cyclase).

LTBP3_MOUSE
NC score	0.004175 (rank : 45)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	475	Shared Neighborhood Hits	2
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

EHMT2_HUMAN
NC score	0.002072 (rank : 46)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

WNK2_HUMAN
NC score	0.000841 (rank : 47)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	1407	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

WNK1_HUMAN
NC score	0.000406 (rank : 48)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	1158	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

EGR2_MOUSE
NC score	-0.000769 (rank : 49)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	745	Shared Neighborhood Hits	3
SwissProt Accessions	P08152	Gene names	Egr2, Egr-2, Krox-20, Zfp-25
Domain Architecture	No domain graphic available
Description	Early growth response protein 2 (EGR-2) (Krox-20 protein).