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Network neighborhood for query Sequence : VMDL1_MOUSE

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VMDL1_MOUSE
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VMDL1_HUMAN
θ value	0 (rank : 1)	NC score	0.997522 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU1, Q9NXP0	Gene names	VMD2L1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

VMDL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

VMDL3_HUMAN
θ value	1.73892e-144 (rank : 3)	NC score	0.982568 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

VMDL3_MOUSE
θ value	2.2711e-144 (rank : 4)	NC score	0.982958 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

VMD2_HUMAN
θ value	2.35023e-141 (rank : 5)	NC score	0.984085 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	O76090, O75904, Q8IUR9, Q8IZ80	Gene names	VMD2
Domain Architecture
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2) (TU15B).

VMDL2_HUMAN
θ value	4.00889e-141 (rank : 6)	NC score	0.992867 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU0	Gene names	VMD2L2
Domain Architecture
Description	Bestrophin-3 (Vitelliform macular dystrophy 2-like protein 2).

VMD2_MOUSE
θ value	1.80368e-133 (rank : 7)	NC score	0.985916 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	O88870, Q6H1V0	Gene names	Vmd2, Bmd1
Domain Architecture	No domain graphic available
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2 homolog).

LTBP3_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.009093 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	502	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SON_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.026230 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	1568	Shared Neighborhood Hits	7
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	1.06291 (rank : 10)	NC score	0.026056 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TTBK1_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.004254 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	1058	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

IRF3_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.011593 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

OAS3_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.012292 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

ZDHC8_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.007415 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

MISS_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.011563 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

PTPRN_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.003344 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

EPN3_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.005679 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

M3K14_HUMAN
θ value	8.99809 (rank : 18)	NC score	-0.000270 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	887	Shared Neighborhood Hits	4
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

PDLI7_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.002429 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	547	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

Hits sorted by NC score

VMDL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

VMDL1_HUMAN
NC score	0.997522 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU1, Q9NXP0	Gene names	VMD2L1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

VMDL2_HUMAN
NC score	0.992867 (rank : 3)	θ value	4.00889e-141 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU0	Gene names	VMD2L2
Domain Architecture
Description	Bestrophin-3 (Vitelliform macular dystrophy 2-like protein 2).

VMD2_MOUSE
NC score	0.985916 (rank : 4)	θ value	1.80368e-133 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	O88870, Q6H1V0	Gene names	Vmd2, Bmd1
Domain Architecture	No domain graphic available
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2 homolog).

VMD2_HUMAN
NC score	0.984085 (rank : 5)	θ value	2.35023e-141 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	O76090, O75904, Q8IUR9, Q8IZ80	Gene names	VMD2
Domain Architecture
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2) (TU15B).

VMDL3_MOUSE
NC score	0.982958 (rank : 6)	θ value	2.2711e-144 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

VMDL3_HUMAN
NC score	0.982568 (rank : 7)	θ value	1.73892e-144 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

SON_HUMAN
NC score	0.026230 (rank : 8)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	1568	Shared Neighborhood Hits	7
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
NC score	0.026056 (rank : 9)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	957	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

OAS3_HUMAN
NC score	0.012292 (rank : 10)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6K5, Q9H3P5	Gene names	OAS3
Domain Architecture	No domain graphic available
Description	2'-5'-oligoadenylate synthetase 3 (EC 2.7.7.-) ((2-5')oligo(A) synthetase 3) (2-5A synthetase 3) (p100 OAS) (p100OAS).

IRF3_HUMAN
NC score	0.011593 (rank : 11)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

MISS_MOUSE
NC score	0.011563 (rank : 12)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	444	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

LTBP3_HUMAN
NC score	0.009093 (rank : 13)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	502	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ZDHC8_HUMAN
NC score	0.007415 (rank : 14)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	234	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

EPN3_HUMAN
NC score	0.005679 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H201, Q9BVN6, Q9NWK2	Gene names	EPN3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

TTBK1_HUMAN
NC score	0.004254 (rank : 16)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	1058	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PTPRN_MOUSE
NC score	0.003344 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PDLI7_HUMAN
NC score	0.002429 (rank : 18)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	547	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR12, Q14250, Q5XG82, Q6NVZ5, Q96C91, Q9BXB8, Q9BXB9	Gene names	PDLIM7, ENIGMA
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

M3K14_HUMAN
NC score	-0.000270 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	887	Shared Neighborhood Hits	4
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).