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Network neighborhood for query Sequence : IRF3_HUMAN

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IRF3_HUMAN
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	129	Target Neighborhood Hits	129	Shared Neighborhood Hits	129
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
θ value	9.78303e-172 (rank : 2)	NC score	0.980458 (rank : 2)
Query Neighborhood Hits	129	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF5_MOUSE
θ value	5.38352e-45 (rank : 3)	NC score	0.900261 (rank : 4)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
θ value	1.46607e-42 (rank : 4)	NC score	0.899644 (rank : 5)
Query Neighborhood Hits	129	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
θ value	2.58786e-39 (rank : 5)	NC score	0.891879 (rank : 6)
Query Neighborhood Hits	129	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	1.28434e-38 (rank : 6)	NC score	0.891415 (rank : 7)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF7_MOUSE
θ value	3.73686e-38 (rank : 7)	NC score	0.900998 (rank : 3)
Query Neighborhood Hits	129	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
θ value	5.39604e-37 (rank : 8)	NC score	0.877161 (rank : 8)
Query Neighborhood Hits	129	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF4_HUMAN
θ value	1.79631e-32 (rank : 9)	NC score	0.870845 (rank : 9)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
θ value	1.16434e-31 (rank : 10)	NC score	0.870277 (rank : 10)
Query Neighborhood Hits	129	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_HUMAN
θ value	1.08979e-29 (rank : 11)	NC score	0.860701 (rank : 11)
Query Neighborhood Hits	129	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
θ value	3.50572e-28 (rank : 12)	NC score	0.856896 (rank : 12)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRTF_HUMAN
θ value	1.42661e-21 (rank : 13)	NC score	0.837651 (rank : 13)
Query Neighborhood Hits	129	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF2_MOUSE
θ value	4.02038e-16 (rank : 14)	NC score	0.779761 (rank : 18)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_HUMAN
θ value	8.95645e-16 (rank : 15)	NC score	0.782186 (rank : 17)
Query Neighborhood Hits	129	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_HUMAN
θ value	2.60593e-15 (rank : 16)	NC score	0.786636 (rank : 15)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
θ value	3.40345e-15 (rank : 17)	NC score	0.783154 (rank : 16)
Query Neighborhood Hits	129	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRTF_MOUSE
θ value	3.76295e-14 (rank : 18)	NC score	0.804459 (rank : 14)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

PTN23_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.029666 (rank : 30)
Query Neighborhood Hits	129	Target Neighborhood Hits	726	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PI5PA_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.051324 (rank : 19)
Query Neighborhood Hits	129	Target Neighborhood Hits	749	Shared Neighborhood Hits	47
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRDM2_HUMAN
θ value	0.0563607 (rank : 21)	NC score	0.014380 (rank : 76)
Query Neighborhood Hits	129	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

MK07_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.007265 (rank : 110)
Query Neighborhood Hits	129	Target Neighborhood Hits	1087	Shared Neighborhood Hits	17
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK07_MOUSE
θ value	0.163984 (rank : 23)	NC score	0.006847 (rank : 113)
Query Neighborhood Hits	129	Target Neighborhood Hits	1054	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

B4GN1_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.033129 (rank : 29)
Query Neighborhood Hits	129	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q00973	Gene names	B4GALNT1, GALGT, SIAT2
Domain Architecture
Description	Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T).

SN1L1_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.002268 (rank : 127)
Query Neighborhood Hits	129	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

GR65_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.035774 (rank : 25)
Query Neighborhood Hits	129	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

WBP11_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.045634 (rank : 20)
Query Neighborhood Hits	129	Target Neighborhood Hits	354	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

GP1BA_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.014311 (rank : 77)
Query Neighborhood Hits	129	Target Neighborhood Hits	407	Shared Neighborhood Hits	7
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

MOT8_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.024546 (rank : 39)
Query Neighborhood Hits	129	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

WBP11_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.044893 (rank : 21)
Query Neighborhood Hits	129	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

FMN2_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.033363 (rank : 28)
Query Neighborhood Hits	129	Target Neighborhood Hits	484	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MMP9_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.012554 (rank : 83)
Query Neighborhood Hits	129	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

PI5PA_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.037798 (rank : 23)
Query Neighborhood Hits	129	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TAF3_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.021330 (rank : 49)
Query Neighborhood Hits	129	Target Neighborhood Hits	568	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TM16H_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.025591 (rank : 37)
Query Neighborhood Hits	129	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

CIC_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.034473 (rank : 27)
Query Neighborhood Hits	129	Target Neighborhood Hits	992	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ENAH_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.016437 (rank : 70)
Query Neighborhood Hits	129	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

FMN2_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.035697 (rank : 26)
Query Neighborhood Hits	129	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

KCNA5_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.010806 (rank : 95)
Query Neighborhood Hits	129	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

ATF5_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.039468 (rank : 22)
Query Neighborhood Hits	129	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

CDN1C_HUMAN
θ value	1.06291 (rank : 41)	NC score	0.028092 (rank : 32)
Query Neighborhood Hits	129	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

FMNL_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.027653 (rank : 33)
Query Neighborhood Hits	129	Target Neighborhood Hits	529	Shared Neighborhood Hits	19
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PELP1_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.026258 (rank : 35)
Query Neighborhood Hits	129	Target Neighborhood Hits	596	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CIC_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.025661 (rank : 36)
Query Neighborhood Hits	129	Target Neighborhood Hits	742	Shared Neighborhood Hits	27
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DIAP2_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.024490 (rank : 40)
Query Neighborhood Hits	129	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

IF4G1_MOUSE
θ value	1.81305 (rank : 46)	NC score	0.022612 (rank : 45)
Query Neighborhood Hits	129	Target Neighborhood Hits	534	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1802_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.016657 (rank : 69)
Query Neighborhood Hits	129	Target Neighborhood Hits	1378	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PHLA1_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.025563 (rank : 38)
Query Neighborhood Hits	129	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

ZN358_HUMAN
θ value	1.81305 (rank : 49)	NC score	-0.001461 (rank : 129)
Query Neighborhood Hits	129	Target Neighborhood Hits	840	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

ATBF1_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.011489 (rank : 91)
Query Neighborhood Hits	129	Target Neighborhood Hits	1547	Shared Neighborhood Hits	21
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
θ value	2.36792 (rank : 51)	NC score	0.011881 (rank : 87)
Query Neighborhood Hits	129	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CEND3_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.014500 (rank : 75)
Query Neighborhood Hits	129	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

DGKK_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.018052 (rank : 60)
Query Neighborhood Hits	129	Target Neighborhood Hits	378	Shared Neighborhood Hits	15
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FOG1_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.005037 (rank : 119)
Query Neighborhood Hits	129	Target Neighborhood Hits	981	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HD_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.023956 (rank : 41)
Query Neighborhood Hits	129	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

JPH4_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.012368 (rank : 84)
Query Neighborhood Hits	129	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

KCNC3_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.009801 (rank : 100)
Query Neighborhood Hits	129	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

ODP2_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.019096 (rank : 56)
Query Neighborhood Hits	129	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

PELP1_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.036945 (rank : 24)
Query Neighborhood Hits	129	Target Neighborhood Hits	709	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RX_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.005096 (rank : 118)
Query Neighborhood Hits	129	Target Neighborhood Hits	423	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

ZPR1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.022852 (rank : 44)
Query Neighborhood Hits	129	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O75312, Q2TAA0	Gene names	ZNF259, ZPR1
Domain Architecture
Description	Zinc-finger protein ZPR1 (Zinc finger protein 259).

CBLB_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.014239 (rank : 78)
Query Neighborhood Hits	129	Target Neighborhood Hits	261	Shared Neighborhood Hits	9
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CEND3_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.013446 (rank : 82)
Query Neighborhood Hits	129	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

DEN1A_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.019210 (rank : 55)
Query Neighborhood Hits	129	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

GPNMB_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.021824 (rank : 47)
Query Neighborhood Hits	129	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

PRR12_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.029661 (rank : 31)
Query Neighborhood Hits	129	Target Neighborhood Hits	460	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PTN23_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.019925 (rank : 52)
Query Neighborhood Hits	129	Target Neighborhood Hits	646	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RFTN1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.017093 (rank : 65)
Query Neighborhood Hits	129	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

VMDL1_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.011593 (rank : 89)
Query Neighborhood Hits	129	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

CJ047_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.018410 (rank : 59)
Query Neighborhood Hits	129	Target Neighborhood Hits	164	Shared Neighborhood Hits	8
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

CNTP1_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.007306 (rank : 109)
Query Neighborhood Hits	129	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

FBLI1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.006249 (rank : 117)
Query Neighborhood Hits	129	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

FOXJ3_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.004751 (rank : 121)
Query Neighborhood Hits	129	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

GNDS_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.010377 (rank : 97)
Query Neighborhood Hits	129	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

SMRC2_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.017210 (rank : 64)
Query Neighborhood Hits	129	Target Neighborhood Hits	499	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMRC2_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.015765 (rank : 73)
Query Neighborhood Hits	129	Target Neighborhood Hits	487	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SON_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.022072 (rank : 46)
Query Neighborhood Hits	129	Target Neighborhood Hits	957	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SYNJ1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.020208 (rank : 50)
Query Neighborhood Hits	129	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T53I2_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.018603 (rank : 57)
Query Neighborhood Hits	129	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

ANTR1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.017066 (rank : 66)
Query Neighborhood Hits	129	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ANTR1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.016993 (rank : 68)
Query Neighborhood Hits	129	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ATN1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.013793 (rank : 80)
Query Neighborhood Hits	129	Target Neighborhood Hits	676	Shared Neighborhood Hits	20
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

FARP2_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.003743 (rank : 123)
Query Neighborhood Hits	129	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GGN_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.019708 (rank : 54)
Query Neighborhood Hits	129	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GLSK_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.008327 (rank : 103)
Query Neighborhood Hits	129	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

IRX3_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.007050 (rank : 111)
Query Neighborhood Hits	129	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

K1949_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.016103 (rank : 71)
Query Neighborhood Hits	129	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

PXK_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.011553 (rank : 90)
Query Neighborhood Hits	129	Target Neighborhood Hits	320	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

RB_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.011270 (rank : 94)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

SN_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.003321 (rank : 125)
Query Neighborhood Hits	129	Target Neighborhood Hits	416	Shared Neighborhood Hits	3
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SPR2F_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.019913 (rank : 53)
Query Neighborhood Hits	129	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TROAP_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.023226 (rank : 43)
Query Neighborhood Hits	129	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TRRAP_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.011420 (rank : 92)
Query Neighborhood Hits	129	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

AFF1_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.007879 (rank : 106)
Query Neighborhood Hits	129	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ATF5_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.026969 (rank : 34)
Query Neighborhood Hits	129	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

CRSP7_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.018417 (rank : 58)
Query Neighborhood Hits	129	Target Neighborhood Hits	247	Shared Neighborhood Hits	19
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

EAF1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.015437 (rank : 74)
Query Neighborhood Hits	129	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

FA13C_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.009852 (rank : 99)
Query Neighborhood Hits	129	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

GGA3_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.007960 (rank : 104)
Query Neighborhood Hits	129	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

HCN2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.005026 (rank : 120)
Query Neighborhood Hits	129	Target Neighborhood Hits	369	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HD_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.021624 (rank : 48)
Query Neighborhood Hits	129	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

KCNN3_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.006756 (rank : 114)
Query Neighborhood Hits	129	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

MYO15_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.008887 (rank : 102)
Query Neighborhood Hits	129	Target Neighborhood Hits	467	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PCLO_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.012290 (rank : 86)
Query Neighborhood Hits	129	Target Neighborhood Hits	2046	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SMCA4_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.004118 (rank : 122)
Query Neighborhood Hits	129	Target Neighborhood Hits	597	Shared Neighborhood Hits	15
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SPR2D_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.012316 (rank : 85)
Query Neighborhood Hits	129	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.017021 (rank : 67)
Query Neighborhood Hits	129	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

WASF2_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.010285 (rank : 98)
Query Neighborhood Hits	129	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

WNK2_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.003698 (rank : 124)
Query Neighborhood Hits	129	Target Neighborhood Hits	1407	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AUTS2_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.015902 (rank : 72)
Query Neighborhood Hits	129	Target Neighborhood Hits	342	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CBLB_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.011720 (rank : 88)
Query Neighborhood Hits	129	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CO039_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.023581 (rank : 42)
Query Neighborhood Hits	129	Target Neighborhood Hits	445	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DIAP1_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.020181 (rank : 51)
Query Neighborhood Hits	129	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DLGP2_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.006300 (rank : 115)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

EAF1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.013866 (rank : 79)
Query Neighborhood Hits	129	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

ENAH_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.017861 (rank : 61)
Query Neighborhood Hits	129	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FA44A_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.007493 (rank : 108)
Query Neighborhood Hits	129	Target Neighborhood Hits	280	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

G3PT_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.008906 (rank : 101)
Query Neighborhood Hits	129	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

GPNMB_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.017498 (rank : 62)
Query Neighborhood Hits	129	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

IQEC3_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.006963 (rank : 112)
Query Neighborhood Hits	129	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PEX6_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.002991 (rank : 126)
Query Neighborhood Hits	129	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PHLA1_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.017483 (rank : 63)
Query Neighborhood Hits	129	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PRRT1_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.013521 (rank : 81)
Query Neighborhood Hits	129	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

RNPL1_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.006265 (rank : 116)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

RXRB_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.001159 (rank : 128)
Query Neighborhood Hits	129	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

SET1A_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.007953 (rank : 105)
Query Neighborhood Hits	129	Target Neighborhood Hits	690	Shared Neighborhood Hits	20
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SPN90_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.007661 (rank : 107)
Query Neighborhood Hits	129	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

UN119_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.011318 (rank : 93)
Query Neighborhood Hits	129	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

WIRE_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.010802 (rank : 96)
Query Neighborhood Hits	129	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

Hits sorted by NC score

IRF3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	129	Target Neighborhood Hits	129	Shared Neighborhood Hits	129
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
NC score	0.980458 (rank : 2)	θ value	9.78303e-172 (rank : 2)
Query Neighborhood Hits	129	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
NC score	0.900998 (rank : 3)	θ value	3.73686e-38 (rank : 7)
Query Neighborhood Hits	129	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF5_MOUSE
NC score	0.900261 (rank : 4)	θ value	5.38352e-45 (rank : 3)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
NC score	0.899644 (rank : 5)	θ value	1.46607e-42 (rank : 4)
Query Neighborhood Hits	129	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
NC score	0.891879 (rank : 6)	θ value	2.58786e-39 (rank : 5)
Query Neighborhood Hits	129	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
NC score	0.891415 (rank : 7)	θ value	1.28434e-38 (rank : 6)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF7_HUMAN
NC score	0.877161 (rank : 8)	θ value	5.39604e-37 (rank : 8)
Query Neighborhood Hits	129	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF4_HUMAN
NC score	0.870845 (rank : 9)	θ value	1.79631e-32 (rank : 9)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
NC score	0.870277 (rank : 10)	θ value	1.16434e-31 (rank : 10)
Query Neighborhood Hits	129	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_HUMAN
NC score	0.860701 (rank : 11)	θ value	1.08979e-29 (rank : 11)
Query Neighborhood Hits	129	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.856896 (rank : 12)	θ value	3.50572e-28 (rank : 12)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRTF_HUMAN
NC score	0.837651 (rank : 13)	θ value	1.42661e-21 (rank : 13)
Query Neighborhood Hits	129	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.804459 (rank : 14)	θ value	3.76295e-14 (rank : 18)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF1_HUMAN
NC score	0.786636 (rank : 15)	θ value	2.60593e-15 (rank : 16)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
NC score	0.783154 (rank : 16)	θ value	3.40345e-15 (rank : 17)
Query Neighborhood Hits	129	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
NC score	0.782186 (rank : 17)	θ value	8.95645e-16 (rank : 15)
Query Neighborhood Hits	129	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.779761 (rank : 18)	θ value	4.02038e-16 (rank : 14)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

PI5PA_HUMAN
NC score	0.051324 (rank : 19)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	129	Target Neighborhood Hits	749	Shared Neighborhood Hits	47
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

WBP11_HUMAN
NC score	0.045634 (rank : 20)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	129	Target Neighborhood Hits	354	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
NC score	0.044893 (rank : 21)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	129	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ATF5_MOUSE
NC score	0.039468 (rank : 22)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	129	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

PI5PA_MOUSE
NC score	0.037798 (rank : 23)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	129	Target Neighborhood Hits	331	Shared Neighborhood Hits	18
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PELP1_MOUSE
NC score	0.036945 (rank : 24)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	129	Target Neighborhood Hits	709	Shared Neighborhood Hits	37
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

GR65_HUMAN
NC score	0.035774 (rank : 25)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	129	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

FMN2_MOUSE
NC score	0.035697 (rank : 26)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	129	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

CIC_HUMAN
NC score	0.034473 (rank : 27)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	129	Target Neighborhood Hits	992	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FMN2_HUMAN
NC score	0.033363 (rank : 28)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	129	Target Neighborhood Hits	484	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

B4GN1_HUMAN
NC score	0.033129 (rank : 29)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	129	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q00973	Gene names	B4GALNT1, GALGT, SIAT2
Domain Architecture
Description	Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N- acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T).

PTN23_MOUSE
NC score	0.029666 (rank : 30)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	129	Target Neighborhood Hits	726	Shared Neighborhood Hits	28
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PRR12_HUMAN
NC score	0.029661 (rank : 31)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	129	Target Neighborhood Hits	460	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CDN1C_HUMAN
NC score	0.028092 (rank : 32)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	129	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

FMNL_HUMAN
NC score	0.027653 (rank : 33)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	129	Target Neighborhood Hits	529	Shared Neighborhood Hits	19
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ATF5_HUMAN
NC score	0.026969 (rank : 34)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	129	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

PELP1_HUMAN
NC score	0.026258 (rank : 35)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	129	Target Neighborhood Hits	596	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CIC_MOUSE
NC score	0.025661 (rank : 36)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	129	Target Neighborhood Hits	742	Shared Neighborhood Hits	27
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TM16H_HUMAN
NC score	0.025591 (rank : 37)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	129	Target Neighborhood Hits	139	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

PHLA1_HUMAN
NC score	0.025563 (rank : 38)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	129	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

MOT8_MOUSE
NC score	0.024546 (rank : 39)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	129	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

DIAP2_MOUSE
NC score	0.024490 (rank : 40)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	129	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

HD_MOUSE
NC score	0.023956 (rank : 41)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	129	Target Neighborhood Hits	116	Shared Neighborhood Hits	6
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

CO039_MOUSE
NC score	0.023581 (rank : 42)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	129	Target Neighborhood Hits	445	Shared Neighborhood Hits	48
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TROAP_HUMAN
NC score	0.023226 (rank : 43)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	129	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZPR1_HUMAN
NC score	0.022852 (rank : 44)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	129	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O75312, Q2TAA0	Gene names	ZNF259, ZPR1
Domain Architecture
Description	Zinc-finger protein ZPR1 (Zinc finger protein 259).

IF4G1_MOUSE
NC score	0.022612 (rank : 45)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	129	Target Neighborhood Hits	534	Shared Neighborhood Hits	40
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

SON_MOUSE
NC score	0.022072 (rank : 46)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	129	Target Neighborhood Hits	957	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GPNMB_HUMAN
NC score	0.021824 (rank : 47)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	129	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

HD_HUMAN
NC score	0.021624 (rank : 48)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	129	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

TAF3_HUMAN
NC score	0.021330 (rank : 49)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	129	Target Neighborhood Hits	568	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SYNJ1_HUMAN
NC score	0.020208 (rank : 50)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	129	Target Neighborhood Hits	498	Shared Neighborhood Hits	26
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

DIAP1_HUMAN
NC score	0.020181 (rank : 51)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	129	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

PTN23_HUMAN
NC score	0.019925 (rank : 52)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	129	Target Neighborhood Hits	646	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SPR2F_MOUSE
NC score	0.019913 (rank : 53)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	129	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

GGN_HUMAN
NC score	0.019708 (rank : 54)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	129	Target Neighborhood Hits	269	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

DEN1A_HUMAN
NC score	0.019210 (rank : 55)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	129	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ODP2_HUMAN
NC score	0.019096 (rank : 56)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	129	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

T53I2_HUMAN
NC score	0.018603 (rank : 57)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	129	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXH6, Q5JX64, Q8IYL5, Q9NU00	Gene names	TP53INP2, C20orf110, PINH
Domain Architecture	No domain graphic available
Description	Tumor protein p53-inducible nuclear protein 2 (p53-inducible protein U) (PIG-U).

CRSP7_HUMAN
NC score	0.018417 (rank : 58)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	129	Target Neighborhood Hits	247	Shared Neighborhood Hits	19
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CJ047_HUMAN
NC score	0.018410 (rank : 59)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	129	Target Neighborhood Hits	164	Shared Neighborhood Hits	8
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

DGKK_HUMAN
NC score	0.018052 (rank : 60)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	129	Target Neighborhood Hits	378	Shared Neighborhood Hits	15
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

ENAH_MOUSE
NC score	0.017861 (rank : 61)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	129	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GPNMB_MOUSE
NC score	0.017498 (rank : 62)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	129	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

PHLA1_MOUSE
NC score	0.017483 (rank : 63)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	129	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

SMRC2_HUMAN
NC score	0.017210 (rank : 64)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	129	Target Neighborhood Hits	499	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

RFTN1_MOUSE
NC score	0.017093 (rank : 65)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	129	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A0D4, Q3U654, Q3U8P6, Q80US1	Gene names	Rftn1, Kiaa0084
Domain Architecture	No domain graphic available
Description	Raftlin (Raft-linking protein).

ANTR1_HUMAN
NC score	0.017066 (rank : 66)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	129	Target Neighborhood Hits	128	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

SPR2E_MOUSE
NC score	0.017021 (rank : 67)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	129	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

ANTR1_MOUSE
NC score	0.016993 (rank : 68)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	129	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

K1802_HUMAN
NC score	0.016657 (rank : 69)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	129	Target Neighborhood Hits	1378	Shared Neighborhood Hits	52
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ENAH_HUMAN
NC score	0.016437 (rank : 70)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	129	Target Neighborhood Hits	784	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

K1949_MOUSE
NC score	0.016103 (rank : 71)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	129	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

AUTS2_HUMAN
NC score	0.015902 (rank : 72)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	129	Target Neighborhood Hits	342	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

SMRC2_MOUSE
NC score	0.015765 (rank : 73)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	129	Target Neighborhood Hits	487	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

EAF1_MOUSE
NC score	0.015437 (rank : 74)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	129	Target Neighborhood Hits	78	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

CEND3_HUMAN
NC score	0.014500 (rank : 75)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	129	Target Neighborhood Hits	275	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

PRDM2_HUMAN
NC score	0.014380 (rank : 76)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	129	Target Neighborhood Hits	1135	Shared Neighborhood Hits	26
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

GP1BA_HUMAN
NC score	0.014311 (rank : 77)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	129	Target Neighborhood Hits	407	Shared Neighborhood Hits	7
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

CBLB_HUMAN
NC score	0.014239 (rank : 78)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	129	Target Neighborhood Hits	261	Shared Neighborhood Hits	9
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

EAF1_HUMAN
NC score	0.013866 (rank : 79)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	129	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

ATN1_HUMAN
NC score	0.013793 (rank : 80)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	129	Target Neighborhood Hits	676	Shared Neighborhood Hits	20
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PRRT1_MOUSE
NC score	0.013521 (rank : 81)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	129	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	O35449	Gene names	Prrt1, Ng5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

CEND3_MOUSE
NC score	0.013446 (rank : 82)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	129	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

MMP9_MOUSE
NC score	0.012554 (rank : 83)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	129	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

JPH4_MOUSE
NC score	0.012368 (rank : 84)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	129	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

SPR2D_MOUSE
NC score	0.012316 (rank : 85)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	129	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

PCLO_HUMAN
NC score	0.012290 (rank : 86)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	129	Target Neighborhood Hits	2046	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ATBF1_MOUSE
NC score	0.011881 (rank : 87)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	129	Target Neighborhood Hits	1841	Shared Neighborhood Hits	30
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CBLB_MOUSE
NC score	0.011720 (rank : 88)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	129	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

VMDL1_MOUSE
NC score	0.011593 (rank : 89)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	129	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGM5, Q8VCM0	Gene names	Vmd2l1
Domain Architecture
Description	Bestrophin-2 (Vitelliform macular dystrophy 2-like protein 1).

PXK_MOUSE
NC score	0.011553 (rank : 90)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	129	Target Neighborhood Hits	320	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

ATBF1_HUMAN
NC score	0.011489 (rank : 91)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	129	Target Neighborhood Hits	1547	Shared Neighborhood Hits	21
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TRRAP_HUMAN
NC score	0.011420 (rank : 92)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	129	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

UN119_HUMAN
NC score	0.011318 (rank : 93)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	129	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q13432, O95126	Gene names	UNC119, RG4
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (HRG4).

RB_MOUSE
NC score	0.011270 (rank : 94)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	129	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P13405	Gene names	Rb1, Rb-1
Domain Architecture
Description	Retinoblastoma-associated protein (PP105) (RB).

KCNA5_HUMAN
NC score	0.010806 (rank : 95)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	129	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

WIRE_HUMAN
NC score	0.010802 (rank : 96)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	129	Target Neighborhood Hits	329	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

GNDS_MOUSE
NC score	0.010377 (rank : 97)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	129	Target Neighborhood Hits	115	Shared Neighborhood Hits	5
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

WASF2_MOUSE
NC score	0.010285 (rank : 98)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	129	Target Neighborhood Hits	315	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

FA13C_MOUSE
NC score	0.009852 (rank : 99)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	129	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

KCNC3_MOUSE
NC score	0.009801 (rank : 100)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	129	Target Neighborhood Hits	173	Shared Neighborhood Hits	7
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

G3PT_MOUSE
NC score	0.008906 (rank : 101)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	129	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q64467, Q60650	Gene names	Gapdhs, Gapd-s, Gapds
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

MYO15_MOUSE
NC score	0.008887 (rank : 102)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	129	Target Neighborhood Hits	467	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

GLSK_HUMAN
NC score	0.008327 (rank : 103)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	129	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GGA3_HUMAN
NC score	0.007960 (rank : 104)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	129	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

SET1A_HUMAN
NC score	0.007953 (rank : 105)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	129	Target Neighborhood Hits	690	Shared Neighborhood Hits	20
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AFF1_MOUSE
NC score	0.007879 (rank : 106)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	129	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SPN90_MOUSE
NC score	0.007661 (rank : 107)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	129	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

FA44A_HUMAN
NC score	0.007493 (rank : 108)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	129	Target Neighborhood Hits	280	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

CNTP1_HUMAN
NC score	0.007306 (rank : 109)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	129	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MK07_HUMAN
NC score	0.007265 (rank : 110)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	129	Target Neighborhood Hits	1087	Shared Neighborhood Hits	17
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

IRX3_MOUSE
NC score	0.007050 (rank : 111)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	129	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

IQEC3_MOUSE
NC score	0.006963 (rank : 112)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	129	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MK07_MOUSE
NC score	0.006847 (rank : 113)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	129	Target Neighborhood Hits	1054	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

KCNN3_MOUSE
NC score	0.006756 (rank : 114)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	129	Target Neighborhood Hits	171	Shared Neighborhood Hits	4
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

DLGP2_MOUSE
NC score	0.006300 (rank : 115)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	129	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

RNPL1_HUMAN
NC score	0.006265 (rank : 116)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	129	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU8, Q96AC9, Q9H033, Q9NVD0	Gene names	RNPEPL1
Domain Architecture
Description	Arginyl aminopeptidase-like 1 (EC 3.4.11.-) (RNPEP-like protein).

FBLI1_HUMAN
NC score	0.006249 (rank : 117)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	129	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUP2, Q5VVE0, Q5VVE1, Q8IX23, Q96T00, Q9UFD6	Gene names	FBLIM1, FBLP1
Domain Architecture
Description	Filamin-binding LIM protein 1 (Filamin-binding LIM protein 1) (FBLP-1) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) (Migfilin).

RX_HUMAN
NC score	0.005096 (rank : 118)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	129	Target Neighborhood Hits	423	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

FOG1_HUMAN
NC score	0.005037 (rank : 119)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	129	Target Neighborhood Hits	981	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HCN2_HUMAN
NC score	0.005026 (rank : 120)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	129	Target Neighborhood Hits	369	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

FOXJ3_HUMAN
NC score	0.004751 (rank : 121)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	129	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

SMCA4_HUMAN
NC score	0.004118 (rank : 122)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	129	Target Neighborhood Hits	597	Shared Neighborhood Hits	15
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

FARP2_HUMAN
NC score	0.003743 (rank : 123)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	129	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

WNK2_HUMAN
NC score	0.003698 (rank : 124)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	129	Target Neighborhood Hits	1407	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SN_MOUSE
NC score	0.003321 (rank : 125)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	129	Target Neighborhood Hits	416	Shared Neighborhood Hits	3
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

PEX6_MOUSE
NC score	0.002991 (rank : 126)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	129	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

SN1L1_HUMAN
NC score	0.002268 (rank : 127)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	129	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	P57059, Q5R2V5, Q86YJ2	Gene names	SNF1LK
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK).

RXRB_MOUSE
NC score	0.001159 (rank : 128)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	129	Target Neighborhood Hits	230	Shared Neighborhood Hits	7
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

ZN358_HUMAN
NC score	-0.001461 (rank : 129)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	129	Target Neighborhood Hits	840	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.