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Network neighborhood for query Sequence : DLGP2_MOUSE

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DLGP2_MOUSE
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DLGP1_HUMAN
θ value	0 (rank : 1)	NC score	0.979830 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DLGP1_MOUSE
θ value	0 (rank : 2)	NC score	0.979571 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

DLGP2_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

DLGP3_HUMAN
θ value	7.01099e-170 (rank : 4)	NC score	0.957506 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

DLGP3_MOUSE
θ value	1.52337e-140 (rank : 5)	NC score	0.955757 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

DLGP4_HUMAN
θ value	1.74296e-136 (rank : 6)	NC score	0.948310 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

DLG7_MOUSE
θ value	4.02038e-16 (rank : 7)	NC score	0.596160 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

DLG7_HUMAN
θ value	5.8054e-15 (rank : 8)	NC score	0.576765 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

CHK2_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.003329 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	859	Shared Neighborhood Hits	5
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

ELOA1_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.022622 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

AKA12_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.023284 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	825	Shared Neighborhood Hits	10
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CI079_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.031529 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

LRP12_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.011362 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

PNPT1_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.032075 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

ANKS1_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.009324 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CENPE_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.003174 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

PTN22_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.008734 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

ANK2_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.008812 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	1615	Shared Neighborhood Hits	18
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ERBB3_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.001769 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	918	Shared Neighborhood Hits	4
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

GNAS3_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.027630 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

SEPT9_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.015022 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	706	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TITIN_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.002322 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AFF1_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.011040 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ANX11_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.005105 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

CCD55_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.009924 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	513	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

MAGC1_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.006845 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

XRN1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.011639 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

ABLM3_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.003930 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

BSN_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.011365 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

DSPP_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.007264 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

E2F3_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.014428 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

E2F3_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.011318 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

GPR75_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.011959 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	O95800, Q6NWR2	Gene names	GPR75
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 75.

GTSE1_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.019692 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

IRS1_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.008848 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

MYH2_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.000690 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	1491	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

PERL_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.007242 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P22079, Q13408	Gene names	LPO, SAPX
Domain Architecture
Description	Lactoperoxidase precursor (EC 1.11.1.7) (LPO) (Salivary peroxidase) (SPO).

STRAP_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.003848 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

CSPG2_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.002608 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	711	Shared Neighborhood Hits	8
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

GRIP2_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.004344 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	256	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

HEM1_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.006312 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

IRF3_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.006300 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

MAFB_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.010137 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

MAFB_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.010144 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MYPT2_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.005005 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	707	Shared Neighborhood Hits	9
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PNPT1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.022881 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

PO3F3_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.004518 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

PO3F3_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.004512 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

TEX14_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.004396 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

Hits sorted by NC score

DLGP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ42, Q6XBF3	Gene names	Dlgap2, Dap2
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 2 (DAP-2) (SAP90/PSD-95-associated protein 2) (SAPAP2) (PSD-95/SAP90-binding protein 2).

DLGP1_HUMAN
NC score	0.979830 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	O14490, O14489, P78335	Gene names	DLGAP1, DAP1, GKAP
Domain Architecture
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD- 95/SAP90-binding protein 1).

DLGP1_MOUSE
NC score	0.979571 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D415, Q52KF6, Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0	Gene names	Dlgap1, Kiaa4162
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (SAP90/PSD-95-associated protein 1) (SAPAP1) (PSD-95/SAP90- binding protein 1).

DLGP3_HUMAN
NC score	0.957506 (rank : 4)	θ value	7.01099e-170 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	55	Shared Neighborhood Hits	9
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

DLGP3_MOUSE
NC score	0.955757 (rank : 5)	θ value	1.52337e-140 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

DLGP4_HUMAN
NC score	0.948310 (rank : 6)	θ value	1.74296e-136 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

DLG7_MOUSE
NC score	0.596160 (rank : 7)	θ value	4.02038e-16 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

DLG7_HUMAN
NC score	0.576765 (rank : 8)	θ value	5.8054e-15 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q15398, Q8NG58	Gene names	DLG7, KIAA0008
Domain Architecture
Description	Discs large homolog 7 (Hepatoma up-regulated protein) (HURP).

PNPT1_HUMAN
NC score	0.032075 (rank : 9)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCS8, Q53SU0, Q68CN1, Q7Z7D1, Q8IWX1, Q96T05, Q9BRU3, Q9BVX0	Gene names	PNPT1, PNPASE
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

CI079_HUMAN
NC score	0.031529 (rank : 10)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	288	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

GNAS3_MOUSE
NC score	0.027630 (rank : 11)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

AKA12_HUMAN
NC score	0.023284 (rank : 12)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	825	Shared Neighborhood Hits	10
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

PNPT1_MOUSE
NC score	0.022881 (rank : 13)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1R3, Q3UEP9, Q810U7, Q812B3, Q8R2U3, Q9DC52	Gene names	Pnpt1, Pnpase
Domain Architecture	No domain graphic available
Description	Polyribonucleotide nucleotidyltransferase 1, mitochondrial precursor (EC 2.7.7.8) (PNPase 1) (Polynucleotide phosphorylase-like protein) (PNPase old-35) (3'-5' RNA exonuclease OLD35).

ELOA1_HUMAN
NC score	0.022622 (rank : 14)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GTSE1_MOUSE
NC score	0.019692 (rank : 15)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SEPT9_HUMAN
NC score	0.015022 (rank : 16)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	706	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

E2F3_HUMAN
NC score	0.014428 (rank : 17)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O00716, Q15000, Q9BZ44	Gene names	E2F3, KIAA0075
Domain Architecture
Description	Transcription factor E2F3 (E2F-3).

GPR75_HUMAN
NC score	0.011959 (rank : 18)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	O95800, Q6NWR2	Gene names	GPR75
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 75.

XRN1_HUMAN
NC score	0.011639 (rank : 19)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZH2, Q4G0S3, Q68D88, Q6AI24, Q6MZS8, Q86WS7, Q8N8U4, Q9UF39	Gene names	XRN1, SEP1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (Strand-exchange protein 1 homolog).

BSN_MOUSE
NC score	0.011365 (rank : 20)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	2057	Shared Neighborhood Hits	14
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LRP12_HUMAN
NC score	0.011362 (rank : 21)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

E2F3_MOUSE
NC score	0.011318 (rank : 22)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	O35261, Q5T0I6	Gene names	E2f3
Domain Architecture	No domain graphic available
Description	Transcription factor E2F3 (E2F-3).

AFF1_MOUSE
NC score	0.011040 (rank : 23)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	351	Shared Neighborhood Hits	8
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MAFB_MOUSE
NC score	0.010144 (rank : 24)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAFB_HUMAN
NC score	0.010137 (rank : 25)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q3, Q9H1F1	Gene names	MAFB, KRML
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B).

CCD55_HUMAN
NC score	0.009924 (rank : 26)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	513	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ANKS1_HUMAN
NC score	0.009324 (rank : 27)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	438	Shared Neighborhood Hits	5
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

IRS1_MOUSE
NC score	0.008848 (rank : 28)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

ANK2_HUMAN
NC score	0.008812 (rank : 29)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	1615	Shared Neighborhood Hits	18
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PTN22_MOUSE
NC score	0.008734 (rank : 30)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

DSPP_HUMAN
NC score	0.007264 (rank : 31)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	645	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PERL_HUMAN
NC score	0.007242 (rank : 32)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P22079, Q13408	Gene names	LPO, SAPX
Domain Architecture
Description	Lactoperoxidase precursor (EC 1.11.1.7) (LPO) (Salivary peroxidase) (SPO).

MAGC1_HUMAN
NC score	0.006845 (rank : 33)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

HEM1_HUMAN
NC score	0.006312 (rank : 34)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P13196	Gene names	ALAS1, ALASH
Domain Architecture
Description	5-aminolevulinate synthase, nonspecific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H).

IRF3_HUMAN
NC score	0.006300 (rank : 35)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

ANX11_MOUSE
NC score	0.005105 (rank : 36)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

MYPT2_HUMAN
NC score	0.005005 (rank : 37)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	707	Shared Neighborhood Hits	9
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PO3F3_HUMAN
NC score	0.004518 (rank : 38)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	P20264, P78379	Gene names	POU3F3, BRN1, OTF8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

PO3F3_MOUSE
NC score	0.004512 (rank : 39)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	P31361	Gene names	Pou3f3, Brn-1, Brn1, Otf8
Domain Architecture
Description	POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein).

TEX14_HUMAN
NC score	0.004396 (rank : 40)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	1103	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

GRIP2_HUMAN
NC score	0.004344 (rank : 41)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	256	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0E4, Q8TEH9, Q9H7H3	Gene names	GRIP2, KIAA1719
Domain Architecture
Description	Glutamate receptor-interacting protein 2 (GRIP2 protein).

ABLM3_HUMAN
NC score	0.003930 (rank : 42)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	293	Shared Neighborhood Hits	3
SwissProt Accessions	O94929, Q658S1, Q68CI5, Q9BV32	Gene names	ABLIM3, KIAA0843
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 3 (Actin-binding LIM protein family member 3) (abLIM-3).

STRAP_MOUSE
NC score	0.003848 (rank : 43)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1Z2	Gene names	Strap, Unrip
Domain Architecture
Description	Serine-threonine kinase receptor-associated protein (UNR-interacting protein).

CHK2_HUMAN
NC score	0.003329 (rank : 44)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	859	Shared Neighborhood Hits	5
SwissProt Accessions	O96017, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HCQ8, Q9UGF0, Q9UGF1	Gene names	CHEK2, CHK2
Domain Architecture
Description	Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (Cds1).

CENPE_HUMAN
NC score	0.003174 (rank : 45)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CSPG2_MOUSE
NC score	0.002608 (rank : 46)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	711	Shared Neighborhood Hits	8
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

TITIN_HUMAN
NC score	0.002322 (rank : 47)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ERBB3_HUMAN
NC score	0.001769 (rank : 48)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	918	Shared Neighborhood Hits	4
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MYH2_HUMAN
NC score	0.000690 (rank : 49)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	1491	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).