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Network neighborhood for query Sequence : IRF7_HUMAN

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IRF7_HUMAN
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF7_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_MOUSE
θ value	4.00889e-141 (rank : 2)	NC score	0.979117 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF3_HUMAN
θ value	5.39604e-37 (rank : 3)	NC score	0.877161 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	129	Shared Neighborhood Hits	23
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF6_MOUSE
θ value	7.79185e-36 (rank : 4)	NC score	0.884277 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_HUMAN
θ value	8.61488e-35 (rank : 5)	NC score	0.883078 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_MOUSE
θ value	2.50655e-34 (rank : 6)	NC score	0.881091 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
θ value	4.72714e-33 (rank : 7)	NC score	0.877516 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF4_MOUSE
θ value	3.17079e-29 (rank : 8)	NC score	0.854764 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
θ value	1.73987e-27 (rank : 9)	NC score	0.854835 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF3_MOUSE
θ value	3.17815e-21 (rank : 10)	NC score	0.866294 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRTF_HUMAN
θ value	3.28887e-18 (rank : 11)	NC score	0.822407 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF8_MOUSE
θ value	9.56915e-18 (rank : 12)	NC score	0.826030 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_HUMAN
θ value	1.24977e-17 (rank : 13)	NC score	0.827928 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRTF_MOUSE
θ value	1.09485e-13 (rank : 14)	NC score	0.787701 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF2_HUMAN
θ value	1.133e-10 (rank : 15)	NC score	0.743105 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
θ value	1.47974e-10 (rank : 16)	NC score	0.740086 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_HUMAN
θ value	5.62301e-10 (rank : 17)	NC score	0.743085 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
θ value	5.62301e-10 (rank : 18)	NC score	0.739868 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

MYBPH_MOUSE
θ value	0.0961366 (rank : 19)	NC score	0.029762 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MTSS1_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.057800 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	504	Shared Neighborhood Hits	14
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PRRT3_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.037957 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MTSS1_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.057437 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

SAPS1_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.029978 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

OGFR_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.031825 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	1582	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TAF4_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.037704 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

UBP31_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.017394 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CK024_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.034258 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

DIAP1_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.016688 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

GNRHR_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.005945 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	473	Shared Neighborhood Hits	2
SwissProt Accessions	Q01776, Q61611	Gene names	Gnrhr
Domain Architecture
Description	Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).

MUC5B_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.021489 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1020	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYPC3_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.017929 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	318	Shared Neighborhood Hits	3
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NSMA2_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.027642 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

TRIP6_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.013511 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

DGKK_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.026877 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	378	Shared Neighborhood Hits	12
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

PRR12_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.039684 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SYN3_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.020378 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

T22D2_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.032685 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CO002_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.031744 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

FOG1_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.006443 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	981	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CA104_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.037986 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K80, Q8NA07	Gene names	C1orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf104.

CO9A1_MOUSE
θ value	2.36792 (rank : 41)	NC score	0.007545 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

MUC2_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.022519 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NFS1_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.023443 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y697, Q6P0L8, Q9NTZ5, Q9Y481	Gene names	NFS1, NIFS
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7).

ALEX_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.024748 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

GP1BA_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.011909 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	407	Shared Neighborhood Hits	7
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

RD23B_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.020538 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

VGLL4_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.024154 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

LPIN3_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.011767 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

SELV_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.027770 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

ACD_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.019525 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ARFG3_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.010297 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

EP300_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.015027 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

NACAM_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.019653 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	1866	Shared Neighborhood Hits	35
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDC6I_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.013755 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

PHX2A_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.002000 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	345	Shared Neighborhood Hits	2
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

PO121_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.024689 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PRR13_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.035727 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SMAD5_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.019647 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD5_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.019669 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

WASF1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.019450 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.019700 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

CCNF_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.010318 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P41002, Q96EG9	Gene names	CCNF
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

HCN2_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.007708 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

NOTC1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.000489 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PCGF6_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.010029 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

SMAD1_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.025303 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMAD1_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.025634 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

ZBTB4_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.000086 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	926	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

CLIC6_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.009274 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CRSP2_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.020968 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	380	Shared Neighborhood Hits	18
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

GRIN1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.013690 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	681	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SHAN1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.004417 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TPSN_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.011275 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

Hits sorted by NC score

IRF7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_MOUSE
NC score	0.979117 (rank : 2)	θ value	4.00889e-141 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF6_MOUSE
NC score	0.884277 (rank : 3)	θ value	7.79185e-36 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_HUMAN
NC score	0.883078 (rank : 4)	θ value	8.61488e-35 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_MOUSE
NC score	0.881091 (rank : 5)	θ value	2.50655e-34 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
NC score	0.877516 (rank : 6)	θ value	4.72714e-33 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF3_HUMAN
NC score	0.877161 (rank : 7)	θ value	5.39604e-37 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	129	Shared Neighborhood Hits	23
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
NC score	0.866294 (rank : 8)	θ value	3.17815e-21 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF4_HUMAN
NC score	0.854835 (rank : 9)	θ value	1.73987e-27 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
NC score	0.854764 (rank : 10)	θ value	3.17079e-29 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_HUMAN
NC score	0.827928 (rank : 11)	θ value	1.24977e-17 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.826030 (rank : 12)	θ value	9.56915e-18 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRTF_HUMAN
NC score	0.822407 (rank : 13)	θ value	3.28887e-18 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.787701 (rank : 14)	θ value	1.09485e-13 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF2_HUMAN
NC score	0.743105 (rank : 15)	θ value	1.133e-10 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_HUMAN
NC score	0.743085 (rank : 16)	θ value	5.62301e-10 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_MOUSE
NC score	0.740086 (rank : 17)	θ value	1.47974e-10 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_MOUSE
NC score	0.739868 (rank : 18)	θ value	5.62301e-10 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

MTSS1_HUMAN
NC score	0.057800 (rank : 19)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	504	Shared Neighborhood Hits	14
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.057437 (rank : 20)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	592	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PRR12_HUMAN
NC score	0.039684 (rank : 21)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CA104_HUMAN
NC score	0.037986 (rank : 22)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q66K80, Q8NA07	Gene names	C1orf104
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf104.

PRRT3_HUMAN
NC score	0.037957 (rank : 23)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TAF4_HUMAN
NC score	0.037704 (rank : 24)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PRR13_HUMAN
NC score	0.035727 (rank : 25)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

CK024_HUMAN
NC score	0.034258 (rank : 26)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

T22D2_HUMAN
NC score	0.032685 (rank : 27)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

OGFR_HUMAN
NC score	0.031825 (rank : 28)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	1582	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CO002_HUMAN
NC score	0.031744 (rank : 29)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

SAPS1_HUMAN
NC score	0.029978 (rank : 30)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MYBPH_MOUSE
NC score	0.029762 (rank : 31)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	290	Shared Neighborhood Hits	7
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

SELV_HUMAN
NC score	0.027770 (rank : 32)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

NSMA2_MOUSE
NC score	0.027642 (rank : 33)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

DGKK_HUMAN
NC score	0.026877 (rank : 34)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	378	Shared Neighborhood Hits	12
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

SMAD1_MOUSE
NC score	0.025634 (rank : 35)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD1_HUMAN
NC score	0.025303 (rank : 36)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

ALEX_HUMAN
NC score	0.024748 (rank : 37)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

PO121_HUMAN
NC score	0.024689 (rank : 38)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

VGLL4_HUMAN
NC score	0.024154 (rank : 39)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q14135, Q7L5V0, Q9BQ78	Gene names	VGLL4, KIAA0121
Domain Architecture	No domain graphic available
Description	Transcription cofactor vestigial-like protein 4 (Vgl-4).

NFS1_HUMAN
NC score	0.023443 (rank : 40)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y697, Q6P0L8, Q9NTZ5, Q9Y481	Gene names	NFS1, NIFS
Domain Architecture
Description	Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7).

MUC2_HUMAN
NC score	0.022519 (rank : 41)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
NC score	0.021489 (rank : 42)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	1020	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CRSP2_HUMAN
NC score	0.020968 (rank : 43)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	380	Shared Neighborhood Hits	18
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

RD23B_MOUSE
NC score	0.020538 (rank : 44)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

SYN3_MOUSE
NC score	0.020378 (rank : 45)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	200	Shared Neighborhood Hits	8
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

WASF1_MOUSE
NC score	0.019700 (rank : 46)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

SMAD5_MOUSE
NC score	0.019669 (rank : 47)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

NACAM_MOUSE
NC score	0.019653 (rank : 48)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	1866	Shared Neighborhood Hits	35
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SMAD5_HUMAN
NC score	0.019647 (rank : 49)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

ACD_HUMAN
NC score	0.019525 (rank : 50)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

WASF1_HUMAN
NC score	0.019450 (rank : 51)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

MYPC3_HUMAN
NC score	0.017929 (rank : 52)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	318	Shared Neighborhood Hits	3
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

UBP31_HUMAN
NC score	0.017394 (rank : 53)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	293	Shared Neighborhood Hits	7
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

DIAP1_HUMAN
NC score	0.016688 (rank : 54)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	784	Shared Neighborhood Hits	11
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EP300_HUMAN
NC score	0.015027 (rank : 55)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

PDC6I_MOUSE
NC score	0.013755 (rank : 56)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	275	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

GRIN1_HUMAN
NC score	0.013690 (rank : 57)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	681	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TRIP6_HUMAN
NC score	0.013511 (rank : 58)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

GP1BA_HUMAN
NC score	0.011909 (rank : 59)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	407	Shared Neighborhood Hits	7
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LPIN3_HUMAN
NC score	0.011767 (rank : 60)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

TPSN_MOUSE
NC score	0.011275 (rank : 61)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R233, O70317, Q91YE0, Q91YE1, Q9QWT7, Q9Z1W3	Gene names	Tapbp, Tapa
Domain Architecture
Description	Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein).

CCNF_HUMAN
NC score	0.010318 (rank : 62)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P41002, Q96EG9	Gene names	CCNF
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

ARFG3_MOUSE
NC score	0.010297 (rank : 63)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

PCGF6_HUMAN
NC score	0.010029 (rank : 64)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

CLIC6_HUMAN
NC score	0.009274 (rank : 65)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

HCN2_MOUSE
NC score	0.007708 (rank : 66)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	278	Shared Neighborhood Hits	8
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

CO9A1_MOUSE
NC score	0.007545 (rank : 67)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	477	Shared Neighborhood Hits	11
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

FOG1_HUMAN
NC score	0.006443 (rank : 68)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	981	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GNRHR_MOUSE
NC score	0.005945 (rank : 69)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	473	Shared Neighborhood Hits	2
SwissProt Accessions	Q01776, Q61611	Gene names	Gnrhr
Domain Architecture
Description	Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).

SHAN1_HUMAN
NC score	0.004417 (rank : 70)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	1041	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PHX2A_HUMAN
NC score	0.002000 (rank : 71)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	345	Shared Neighborhood Hits	2
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

NOTC1_MOUSE
NC score	0.000489 (rank : 72)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ZBTB4_HUMAN
NC score	0.000086 (rank : 73)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	926	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).