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Network neighborhood for query Sequence : IRF1_HUMAN

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IRF1_HUMAN
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF1_HUMAN
θ value	6.77497e-173 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
θ value	7.04359e-154 (rank : 2)	NC score	0.997469 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
θ value	8.28633e-54 (rank : 3)	NC score	0.949114 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
θ value	5.93839e-52 (rank : 4)	NC score	0.944367 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF8_HUMAN
θ value	1.92365e-26 (rank : 5)	NC score	0.864427 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
θ value	4.28545e-26 (rank : 6)	NC score	0.862776 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_HUMAN
θ value	9.54697e-26 (rank : 7)	NC score	0.858101 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
θ value	1.24688e-25 (rank : 8)	NC score	0.859456 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF5_HUMAN
θ value	8.93572e-24 (rank : 9)	NC score	0.844212 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
θ value	8.93572e-24 (rank : 10)	NC score	0.842592 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
θ value	7.56453e-23 (rank : 11)	NC score	0.840709 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	7.56453e-23 (rank : 12)	NC score	0.840676 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_HUMAN
θ value	3.17815e-21 (rank : 13)	NC score	0.846080 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
θ value	5.07402e-19 (rank : 14)	NC score	0.838251 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF3_HUMAN
θ value	2.60593e-15 (rank : 15)	NC score	0.786636 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
θ value	3.40345e-15 (rank : 16)	NC score	0.796972 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
θ value	1.33837e-11 (rank : 17)	NC score	0.770931 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
θ value	5.62301e-10 (rank : 18)	NC score	0.743085 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

CI079_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.033483 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	288	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

EVL_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.026166 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	203	Shared Neighborhood Hits	3
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

HSF2_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.019010 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

EVL_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.025894 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SDPR_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.019742 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	485	Shared Neighborhood Hits	3
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

MAML3_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.013072 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PRIC2_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.003488 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3G6	Gene names	PRICKLE2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.

RNC_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.010871 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

Hits sorted by NC score

IRF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.77497e-173 (rank : 1)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	26
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
NC score	0.997469 (rank : 2)	θ value	7.04359e-154 (rank : 2)
Query Neighborhood Hits	26	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
NC score	0.949114 (rank : 3)	θ value	8.28633e-54 (rank : 3)
Query Neighborhood Hits	26	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.944367 (rank : 4)	θ value	5.93839e-52 (rank : 4)
Query Neighborhood Hits	26	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF8_HUMAN
NC score	0.864427 (rank : 5)	θ value	1.92365e-26 (rank : 5)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.862776 (rank : 6)	θ value	4.28545e-26 (rank : 6)
Query Neighborhood Hits	26	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
NC score	0.859456 (rank : 7)	θ value	1.24688e-25 (rank : 8)
Query Neighborhood Hits	26	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
NC score	0.858101 (rank : 8)	θ value	9.54697e-26 (rank : 7)
Query Neighborhood Hits	26	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRTF_HUMAN
NC score	0.846080 (rank : 9)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	26	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF5_HUMAN
NC score	0.844212 (rank : 10)	θ value	8.93572e-24 (rank : 9)
Query Neighborhood Hits	26	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
NC score	0.842592 (rank : 11)	θ value	8.93572e-24 (rank : 10)
Query Neighborhood Hits	26	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
NC score	0.840709 (rank : 12)	θ value	7.56453e-23 (rank : 11)
Query Neighborhood Hits	26	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
NC score	0.840676 (rank : 13)	θ value	7.56453e-23 (rank : 12)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_MOUSE
NC score	0.838251 (rank : 14)	θ value	5.07402e-19 (rank : 14)
Query Neighborhood Hits	26	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF3_MOUSE
NC score	0.796972 (rank : 15)	θ value	3.40345e-15 (rank : 16)
Query Neighborhood Hits	26	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_HUMAN
NC score	0.786636 (rank : 16)	θ value	2.60593e-15 (rank : 15)
Query Neighborhood Hits	26	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
NC score	0.770931 (rank : 17)	θ value	1.33837e-11 (rank : 17)
Query Neighborhood Hits	26	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
NC score	0.743085 (rank : 18)	θ value	5.62301e-10 (rank : 18)
Query Neighborhood Hits	26	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

CI079_HUMAN
NC score	0.033483 (rank : 19)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	26	Target Neighborhood Hits	288	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

EVL_MOUSE
NC score	0.026166 (rank : 20)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	26	Target Neighborhood Hits	203	Shared Neighborhood Hits	3
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_HUMAN
NC score	0.025894 (rank : 21)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	26	Target Neighborhood Hits	260	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SDPR_MOUSE
NC score	0.019742 (rank : 22)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	26	Target Neighborhood Hits	485	Shared Neighborhood Hits	3
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

HSF2_MOUSE
NC score	0.019010 (rank : 23)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	26	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

MAML3_HUMAN
NC score	0.013072 (rank : 24)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	26	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

RNC_HUMAN
NC score	0.010871 (rank : 25)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	26	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

PRIC2_HUMAN
NC score	0.003488 (rank : 26)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	26	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3G6	Gene names	PRICKLE2
Domain Architecture	No domain graphic available
Description	Prickle-like protein 2.