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Network neighborhood for query Sequence : GPNMB_MOUSE

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GPNMB_MOUSE
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GPNMB_HUMAN
θ value	0 (rank : 1)	NC score	0.985487 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

GPNMB_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

PME17_HUMAN
θ value	1.98146e-39 (rank : 3)	NC score	0.753093 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

PME17_MOUSE
θ value	2.05049e-36 (rank : 4)	NC score	0.777484 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

PKD1_HUMAN
θ value	5.44631e-05 (rank : 5)	NC score	0.116106 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SON_HUMAN
θ value	0.0113563 (rank : 6)	NC score	0.051173 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

JIP3_HUMAN
θ value	0.47712 (rank : 7)	NC score	0.029869 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	1039	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

SPR1A_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.048780 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

SPR1B_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.052606 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

GP152_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.021161 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	607	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

MILK1_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.033489 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	788	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RGS3_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.023888 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	1621	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MICA2_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.019547 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

DAF2_MOUSE
θ value	2.36792 (rank : 14)	NC score	0.016138 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

GIDRP_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.051335 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5L2, O60598, Q5W0B4, Q5W0B5, Q86VT9, Q8N9H0	Gene names	GIDRP88, C10orf28
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 (Putative mitochondrial space protein 32.1).

NACAM_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.029362 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	1866	Shared Neighborhood Hits	23
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RGS3_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.021951 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	1375	Shared Neighborhood Hits	15
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SON_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.057311 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	957	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZEP1_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.010128 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	1063	Shared Neighborhood Hits	13
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

TCGAP_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.013327 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	872	Shared Neighborhood Hits	14
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TPO_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.030526 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

EP15R_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.008796 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	10
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

KCNQ1_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.011738 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

CEL_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.012258 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DLG5_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.008669 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	1088	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

K1802_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.014899 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	1596	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PCOC1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.008988 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

RBM16_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.028369 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	300	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

TARSH_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.028378 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	768	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TTLL5_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.013306 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

AOC2_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.010966 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

KCNK6_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.010613 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

NCOA6_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.024925 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	1202	Shared Neighborhood Hits	17
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.028653 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1076	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PIGQ_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.017552 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

CTRO_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.001659 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	2092	Shared Neighborhood Hits	9
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.001356 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	2344	Shared Neighborhood Hits	11
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

IRF3_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.017498 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

LEUK_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.019961 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

RTP3_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.015033 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SPR2I_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.052142 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

Hits sorted by NC score

GPNMB_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

GPNMB_HUMAN
NC score	0.985487 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q14956, Q6UVX1, Q8N1A1	Gene names	GPNMB, HGFIN, NMB
Domain Architecture
Description	Transmembrane glycoprotein NMB precursor (Transmembrane glycoprotein HGFIN).

PME17_MOUSE
NC score	0.777484 (rank : 3)	θ value	2.05049e-36 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

PME17_HUMAN
NC score	0.753093 (rank : 4)	θ value	1.98146e-39 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

PKD1_HUMAN
NC score	0.116106 (rank : 5)	θ value	5.44631e-05 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

SON_MOUSE
NC score	0.057311 (rank : 6)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	957	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR1B_HUMAN
NC score	0.052606 (rank : 7)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

SPR2I_MOUSE
NC score	0.052142 (rank : 8)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

GIDRP_HUMAN
NC score	0.051335 (rank : 9)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5L2, O60598, Q5W0B4, Q5W0B5, Q86VT9, Q8N9H0	Gene names	GIDRP88, C10orf28
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 (Putative mitochondrial space protein 32.1).

SON_HUMAN
NC score	0.051173 (rank : 10)	θ value	0.0113563 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR1A_HUMAN
NC score	0.048780 (rank : 11)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

MILK1_MOUSE
NC score	0.033489 (rank : 12)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	788	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TPO_MOUSE
NC score	0.030526 (rank : 13)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

JIP3_HUMAN
NC score	0.029869 (rank : 14)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	1039	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

NACAM_MOUSE
NC score	0.029362 (rank : 15)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	1866	Shared Neighborhood Hits	23
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCOA6_MOUSE
NC score	0.028653 (rank : 16)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	1076	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

TARSH_HUMAN
NC score	0.028378 (rank : 17)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	768	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

RBM16_HUMAN
NC score	0.028369 (rank : 18)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	300	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

NCOA6_HUMAN
NC score	0.024925 (rank : 19)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	1202	Shared Neighborhood Hits	17
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RGS3_MOUSE
NC score	0.023888 (rank : 20)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	1621	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RGS3_HUMAN
NC score	0.021951 (rank : 21)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	1375	Shared Neighborhood Hits	15
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GP152_MOUSE
NC score	0.021161 (rank : 22)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	607	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

LEUK_HUMAN
NC score	0.019961 (rank : 23)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

MICA2_HUMAN
NC score	0.019547 (rank : 24)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	O94851, Q7Z3A8	Gene names	MICAL2, KIAA0750
Domain Architecture
Description	Protein MICAL-2.

PIGQ_HUMAN
NC score	0.017552 (rank : 25)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRB3, O14927, Q96G00, Q96S22, Q9UJH4	Gene names	PIGQ, GPI1
Domain Architecture
Description	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) (N-acetylglucosamyl transferase component GPI1).

IRF3_HUMAN
NC score	0.017498 (rank : 26)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

DAF2_MOUSE
NC score	0.016138 (rank : 27)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

RTP3_MOUSE
NC score	0.015033 (rank : 28)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	374	Shared Neighborhood Hits	12
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

K1802_MOUSE
NC score	0.014899 (rank : 29)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	1596	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

TCGAP_HUMAN
NC score	0.013327 (rank : 30)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	872	Shared Neighborhood Hits	14
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TTLL5_HUMAN
NC score	0.013306 (rank : 31)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

CEL_HUMAN
NC score	0.012258 (rank : 32)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

KCNQ1_MOUSE
NC score	0.011738 (rank : 33)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	175	Shared Neighborhood Hits	5
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

AOC2_MOUSE
NC score	0.010966 (rank : 34)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q812C9, Q80WP3	Gene names	Aoc2
Domain Architecture
Description	Retina-specific copper amine oxidase precursor (EC 1.4.3.6) (RAO) (Amine oxidase [copper-containing]).

KCNK6_HUMAN
NC score	0.010613 (rank : 35)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

ZEP1_MOUSE
NC score	0.010128 (rank : 36)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	1063	Shared Neighborhood Hits	13
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

PCOC1_HUMAN
NC score	0.008988 (rank : 37)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

EP15R_MOUSE
NC score	0.008796 (rank : 38)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	1135	Shared Neighborhood Hits	10
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

DLG5_HUMAN
NC score	0.008669 (rank : 39)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	1088	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CTRO_HUMAN
NC score	0.001659 (rank : 40)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	2092	Shared Neighborhood Hits	9
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
NC score	0.001356 (rank : 41)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	2344	Shared Neighborhood Hits	11
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).