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Network neighborhood for query Sequence : PCOC1_HUMAN

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PCOC1_HUMAN
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PCOC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	0 (rank : 2)	NC score	0.992378 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_MOUSE
θ value	4.04623e-109 (rank : 3)	NC score	0.979901 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	73	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_HUMAN
θ value	5.46864e-106 (rank : 4)	NC score	0.980857 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	73	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL2_MOUSE
θ value	1.91475e-42 (rank : 5)	NC score	0.822958 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	240	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
θ value	5.57106e-42 (rank : 6)	NC score	0.820245 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_HUMAN
θ value	9.50281e-42 (rank : 7)	NC score	0.820850 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	241	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	1.2411e-41 (rank : 8)	NC score	0.817934 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	237	Shared Neighborhood Hits	68
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_MOUSE
θ value	1.3722e-40 (rank : 9)	NC score	0.816334 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
θ value	2.34062e-40 (rank : 10)	NC score	0.816171 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	233	Shared Neighborhood Hits	69
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

NRP1_HUMAN
θ value	1.57e-36 (rank : 11)	NC score	0.760664 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CUBN_HUMAN
θ value	1.32909e-35 (rank : 12)	NC score	0.571841 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	482	Shared Neighborhood Hits	71
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NRP1_MOUSE
θ value	3.86705e-35 (rank : 13)	NC score	0.759560 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CUBN_MOUSE
θ value	2.50655e-34 (rank : 14)	NC score	0.569073 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	477	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NRP2_HUMAN
θ value	2.77131e-33 (rank : 15)	NC score	0.768624 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	1.37539e-32 (rank : 16)	NC score	0.769586 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MFRP_MOUSE
θ value	1.52067e-31 (rank : 17)	NC score	0.794315 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CSMD2_HUMAN
θ value	3.3877e-31 (rank : 18)	NC score	0.673438 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

MFRP_HUMAN
θ value	8.3442e-30 (rank : 19)	NC score	0.788880 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CSMD1_MOUSE
θ value	3.87602e-27 (rank : 20)	NC score	0.660257 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	193	Shared Neighborhood Hits	70
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
θ value	1.12775e-26 (rank : 21)	NC score	0.657738 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

DMBT1_MOUSE
θ value	7.30988e-26 (rank : 22)	NC score	0.653758 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	134	Shared Neighborhood Hits	69
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

CUZD1_HUMAN
θ value	1.16704e-23 (rank : 23)	NC score	0.800051 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CSMD3_HUMAN
θ value	1.42661e-21 (rank : 24)	NC score	0.651402 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUZD1_MOUSE
θ value	9.24701e-21 (rank : 25)	NC score	0.784070 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

ST14_HUMAN
θ value	1.13037e-18 (rank : 26)	NC score	0.354286 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	409	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

MASP1_MOUSE
θ value	2.7842e-17 (rank : 27)	NC score	0.445836 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	68
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

C1R_HUMAN
θ value	4.74913e-17 (rank : 28)	NC score	0.469765 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ST14_MOUSE
θ value	6.20254e-17 (rank : 29)	NC score	0.353597 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	69
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

MASP1_HUMAN
θ value	1.80466e-16 (rank : 30)	NC score	0.453490 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

DMBT1_HUMAN
θ value	5.25075e-16 (rank : 31)	NC score	0.560307 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

MASP2_HUMAN
θ value	5.25075e-16 (rank : 32)	NC score	0.451861 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NETO2_HUMAN
θ value	6.85773e-16 (rank : 33)	NC score	0.789227 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	6.85773e-16 (rank : 34)	NC score	0.787163 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

GP126_HUMAN
θ value	4.44505e-15 (rank : 35)	NC score	0.480801 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

NETO1_HUMAN
θ value	5.8054e-15 (rank : 36)	NC score	0.786539 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

MASP2_MOUSE
θ value	9.90251e-15 (rank : 37)	NC score	0.446421 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NETO1_MOUSE
θ value	2.20605e-14 (rank : 38)	NC score	0.786023 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TSG6_HUMAN
θ value	6.41864e-14 (rank : 39)	NC score	0.739207 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	6.41864e-14 (rank : 40)	NC score	0.737061 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

C1RB_MOUSE
θ value	3.18553e-13 (rank : 41)	NC score	0.457981 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	380	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1RA_MOUSE
θ value	4.16044e-13 (rank : 42)	NC score	0.463765 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	379	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

DCBD2_HUMAN
θ value	9.26847e-13 (rank : 43)	NC score	0.631004 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

C1S_HUMAN
θ value	4.59992e-12 (rank : 44)	NC score	0.445977 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	359	Shared Neighborhood Hits	67
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

DCBD2_MOUSE
θ value	7.84624e-12 (rank : 45)	NC score	0.612652 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

CS1A_MOUSE
θ value	1.74796e-11 (rank : 46)	NC score	0.441371 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

LRP12_HUMAN
θ value	2.28291e-11 (rank : 47)	NC score	0.618219 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	205	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	2.28291e-11 (rank : 48)	NC score	0.622199 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CS1B_MOUSE
θ value	3.89403e-11 (rank : 49)	NC score	0.439001 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	361	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LRP3_HUMAN
θ value	6.64225e-11 (rank : 50)	NC score	0.529893 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	280	Shared Neighborhood Hits	73
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

SEZ6L_HUMAN
θ value	1.38499e-08 (rank : 51)	NC score	0.624363 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

DCBD1_HUMAN
θ value	1.53129e-07 (rank : 52)	NC score	0.548769 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

KREM2_HUMAN
θ value	1.29631e-06 (rank : 53)	NC score	0.476310 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

SCUB3_HUMAN
θ value	1.29631e-06 (rank : 54)	NC score	0.246743 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	428	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	1.69304e-06 (rank : 55)	NC score	0.248469 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	442	Shared Neighborhood Hits	66
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PDGFD_HUMAN
θ value	2.88788e-06 (rank : 56)	NC score	0.699189 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

ENTK_MOUSE
θ value	4.92598e-06 (rank : 57)	NC score	0.310828 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PDGFD_MOUSE
θ value	8.40245e-06 (rank : 58)	NC score	0.685001 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

DCBD1_MOUSE
θ value	2.44474e-05 (rank : 59)	NC score	0.636078 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

KREM1_HUMAN
θ value	5.44631e-05 (rank : 60)	NC score	0.461799 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	5.44631e-05 (rank : 61)	NC score	0.449477 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

TMPS6_MOUSE
θ value	0.000270298 (rank : 62)	NC score	0.160919 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	341	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

KREM2_MOUSE
θ value	0.000602161 (rank : 63)	NC score	0.428318 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ENTK_HUMAN
θ value	0.00102713 (rank : 64)	NC score	0.276954 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	310	Shared Neighborhood Hits	68
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS6_HUMAN
θ value	0.00390308 (rank : 65)	NC score	0.159255 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CSKI1_MOUSE
θ value	0.0563607 (rank : 66)	NC score	0.012730 (rank : 445)
Query Neighborhood Hits	146	Target Neighborhood Hits	1031	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DLGP3_HUMAN
θ value	0.0736092 (rank : 67)	NC score	0.028458 (rank : 422)
Query Neighborhood Hits	146	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

SCMH1_MOUSE
θ value	0.0736092 (rank : 68)	NC score	0.029121 (rank : 421)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

NET1_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.023322 (rank : 426)
Query Neighborhood Hits	146	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

OTU7A_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.021142 (rank : 428)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

CDCP1_HUMAN
θ value	0.21417 (rank : 71)	NC score	0.087917 (rank : 220)
Query Neighborhood Hits	146	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

LRP10_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.249339 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SETBP_HUMAN
θ value	0.279714 (rank : 73)	NC score	0.038189 (rank : 420)
Query Neighborhood Hits	146	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_MOUSE
θ value	0.279714 (rank : 74)	NC score	0.038365 (rank : 419)
Query Neighborhood Hits	146	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CSKI1_HUMAN
θ value	0.47712 (rank : 75)	NC score	0.011281 (rank : 449)
Query Neighborhood Hits	146	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NET1_HUMAN
θ value	0.47712 (rank : 76)	NC score	0.024428 (rank : 424)
Query Neighborhood Hits	146	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

MEF2D_HUMAN
θ value	0.62314 (rank : 77)	NC score	0.013490 (rank : 441)
Query Neighborhood Hits	146	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

NACAM_MOUSE
θ value	0.62314 (rank : 78)	NC score	0.021650 (rank : 427)
Query Neighborhood Hits	146	Target Neighborhood Hits	1866	Shared Neighborhood Hits	57
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SCMH1_HUMAN
θ value	0.813845 (rank : 79)	NC score	0.024606 (rank : 423)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q96GD3, Q5VT76, Q6IAJ4, Q8WU48, Q9UKM5, Q9UKM6	Gene names	SCMH1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

SYN3_MOUSE
θ value	0.813845 (rank : 80)	NC score	0.020373 (rank : 429)
Query Neighborhood Hits	146	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

DLGP3_MOUSE
θ value	1.06291 (rank : 81)	NC score	0.024318 (rank : 425)
Query Neighborhood Hits	146	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

PRP1_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.013152 (rank : 443)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	15
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SFPQ_HUMAN
θ value	1.06291 (rank : 83)	NC score	0.007336 (rank : 461)
Query Neighborhood Hits	146	Target Neighborhood Hits	986	Shared Neighborhood Hits	18
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ATN1_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.017688 (rank : 433)
Query Neighborhood Hits	146	Target Neighborhood Hits	676	Shared Neighborhood Hits	16
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

HCN4_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.006622 (rank : 464)
Query Neighborhood Hits	146	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

PCLO_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.013726 (rank : 440)
Query Neighborhood Hits	146	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRELP_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.001778 (rank : 478)
Query Neighborhood Hits	146	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

WNK2_HUMAN
θ value	1.38821 (rank : 88)	NC score	-0.001661 (rank : 483)
Query Neighborhood Hits	146	Target Neighborhood Hits	1407	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZSCA1_HUMAN
θ value	1.38821 (rank : 89)	NC score	-0.002613 (rank : 484)
Query Neighborhood Hits	146	Target Neighborhood Hits	724	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

APXL_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.014308 (rank : 437)
Query Neighborhood Hits	146	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

PRRT3_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.018941 (rank : 431)
Query Neighborhood Hits	146	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SYN3_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.019775 (rank : 430)
Query Neighborhood Hits	146	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

TITIN_HUMAN
θ value	1.81305 (rank : 93)	NC score	-0.003303 (rank : 485)
Query Neighborhood Hits	146	Target Neighborhood Hits	2923	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN553_MOUSE
θ value	1.81305 (rank : 94)	NC score	-0.005096 (rank : 491)
Query Neighborhood Hits	146	Target Neighborhood Hits	744	Shared Neighborhood Hits	7
SwissProt Accessions	Q3US17, Q3UFP3, Q8R0V0, Q921H7	Gene names	Znf553, Zfp553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

CCD96_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.005620 (rank : 467)
Query Neighborhood Hits	146	Target Neighborhood Hits	595	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

JADE2_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.013418 (rank : 442)
Query Neighborhood Hits	146	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

SMP1L_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.008056 (rank : 459)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

CI079_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.017207 (rank : 434)
Query Neighborhood Hits	146	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CJ047_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.015416 (rank : 436)
Query Neighborhood Hits	146	Target Neighborhood Hits	164	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

COMP_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.039206 (rank : 418)
Query Neighborhood Hits	146	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

MILK1_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.004629 (rank : 471)
Query Neighborhood Hits	146	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MMP15_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.002762 (rank : 476)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MUCDL_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.005354 (rank : 469)
Query Neighborhood Hits	146	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RERE_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.010515 (rank : 453)
Query Neighborhood Hits	146	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SF01_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.009990 (rank : 454)
Query Neighborhood Hits	146	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SHAN2_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.012922 (rank : 444)
Query Neighborhood Hits	146	Target Neighborhood Hits	446	Shared Neighborhood Hits	14
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SYAP1_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.012521 (rank : 446)
Query Neighborhood Hits	146	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

TTP_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.009529 (rank : 455)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

UBP2L_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.015753 (rank : 435)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

CD2AP_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.002956 (rank : 475)
Query Neighborhood Hits	146	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

DSCL1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.000036 (rank : 482)
Query Neighborhood Hits	146	Target Neighborhood Hits	589	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

ELF1_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.003965 (rank : 473)
Query Neighborhood Hits	146	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

FGFP3_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.014228 (rank : 438)
Query Neighborhood Hits	146	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

GPNMB_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.008988 (rank : 457)
Query Neighborhood Hits	146	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

MLL4_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.007100 (rank : 462)
Query Neighborhood Hits	146	Target Neighborhood Hits	722	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRG4_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.011084 (rank : 451)
Query Neighborhood Hits	146	Target Neighborhood Hits	624	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SYN2_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.017777 (rank : 432)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

SYNJ1_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.006821 (rank : 463)
Query Neighborhood Hits	146	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TAU_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.014086 (rank : 439)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	31
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TMPS7_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.173297 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

ZF276_MOUSE
θ value	5.27518 (rank : 121)	NC score	-0.004829 (rank : 489)
Query Neighborhood Hits	146	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CE64, Q9ESV2	Gene names	Zfp276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 (Zfp-276).

BRD4_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.003213 (rank : 474)
Query Neighborhood Hits	146	Target Neighborhood Hits	851	Shared Neighborhood Hits	18
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

DAF_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.124251 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	17
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

MAGI2_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.002237 (rank : 477)
Query Neighborhood Hits	146	Target Neighborhood Hits	373	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MINT_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.006251 (rank : 466)
Query Neighborhood Hits	146	Target Neighborhood Hits	1514	Shared Neighborhood Hits	41
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PACS1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.011589 (rank : 447)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PCLO_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.009288 (rank : 456)
Query Neighborhood Hits	146	Target Neighborhood Hits	2046	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RTN1_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.005485 (rank : 468)
Query Neighborhood Hits	146	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

SHAN2_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.011133 (rank : 450)
Query Neighborhood Hits	146	Target Neighborhood Hits	346	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SIGIR_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.006286 (rank : 465)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

TAU_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.010608 (rank : 452)
Query Neighborhood Hits	146	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TGBR3_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.058074 (rank : 393)
Query Neighborhood Hits	146	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

ZN219_HUMAN
θ value	6.88961 (rank : 133)	NC score	-0.004416 (rank : 487)
Query Neighborhood Hits	146	Target Neighborhood Hits	876	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

AF17_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.004830 (rank : 470)
Query Neighborhood Hits	146	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

ARHGG_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.001564 (rank : 480)
Query Neighborhood Hits	146	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CENG1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.001553 (rank : 481)
Query Neighborhood Hits	146	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DCAK1_HUMAN
θ value	8.99809 (rank : 137)	NC score	-0.005807 (rank : 492)
Query Neighborhood Hits	146	Target Neighborhood Hits	877	Shared Neighborhood Hits	7
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

JHD2B_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.007492 (rank : 460)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

LRP10_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.213413 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NMDE4_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.001589 (rank : 479)
Query Neighborhood Hits	146	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

OBSCN_HUMAN
θ value	8.99809 (rank : 141)	NC score	-0.004691 (rank : 488)
Query Neighborhood Hits	146	Target Neighborhood Hits	1931	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PACS1_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.011322 (rank : 448)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SAM14_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.008330 (rank : 458)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SPEG_HUMAN
θ value	8.99809 (rank : 144)	NC score	-0.004967 (rank : 490)
Query Neighborhood Hits	146	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAD3L_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.004452 (rank : 472)
Query Neighborhood Hits	146	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

WNK4_HUMAN
θ value	8.99809 (rank : 146)	NC score	-0.003994 (rank : 486)
Query Neighborhood Hits	146	Target Neighborhood Hits	1043	Shared Neighborhood Hits	14
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ACRO_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.091012 (rank : 202)
Query Neighborhood Hits	146	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.091419 (rank : 196)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.088267 (rank : 216)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

APOH_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.131379 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

APOH_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.117320 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

ASTL_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.210689 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.214694 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATRN_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.290029 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	525	Shared Neighborhood Hits	55
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.282935 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BSSP4_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.091627 (rank : 195)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.092372 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C163A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.066685 (rank : 350)
Query Neighborhood Hits	146	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163A_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.067001 (rank : 347)
Query Neighborhood Hits	146	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.065830 (rank : 359)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

C1QR1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.076364 (rank : 298)
Query Neighborhood Hits	146	Target Neighborhood Hits	493	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.096639 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	342	Shared Neighborhood Hits	27
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C4BB_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.158600 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

C4BP_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.131569 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

C4BP_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.133807 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CAP7_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.066963 (rank : 348)
Query Neighborhood Hits	146	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

CATG_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.075738 (rank : 305)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.078550 (rank : 281)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CD248_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.085670 (rank : 238)
Query Neighborhood Hits	146	Target Neighborhood Hits	679	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.092664 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	578	Shared Neighborhood Hits	41
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD320_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.082293 (rank : 259)
Query Neighborhood Hits	146	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD5L_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.060104 (rank : 385)
Query Neighborhood Hits	146	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

CD5L_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.056626 (rank : 399)
Query Neighborhood Hits	146	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

CD6_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.056014 (rank : 401)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CD6_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.052669 (rank : 408)
Query Neighborhood Hits	146	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

CD97_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.069290 (rank : 335)
Query Neighborhood Hits	146	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.051459 (rank : 411)
Query Neighborhood Hits	146	Target Neighborhood Hits	295	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDCP1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.064105 (rank : 366)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

CFAB_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.130971 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.132211 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAD_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.080237 (rank : 268)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.080614 (rank : 267)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAH_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.120419 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.119070 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CFAI_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.116442 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.120251 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLC14_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.058880 (rank : 389)
Query Neighborhood Hits	146	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.063002 (rank : 370)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLCR_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.088994 (rank : 214)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CNTP1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.052452 (rank : 409)
Query Neighborhood Hits	146	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.055202 (rank : 402)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.066149 (rank : 354)
Query Neighborhood Hits	146	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.062195 (rank : 378)
Query Neighborhood Hits	146	Target Neighborhood Hits	194	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.062746 (rank : 372)
Query Neighborhood Hits	146	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.061495 (rank : 379)
Query Neighborhood Hits	146	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.062379 (rank : 376)
Query Neighborhood Hits	146	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO2_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.124362 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.127279 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.087965 (rank : 218)
Query Neighborhood Hits	146	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.062740 (rank : 374)
Query Neighborhood Hits	146	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.053633 (rank : 404)
Query Neighborhood Hits	146	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.058888 (rank : 388)
Query Neighborhood Hits	146	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.114593 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	453	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.112439 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CPXM1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.063654 (rank : 368)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.060182 (rank : 384)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM2_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.074113 (rank : 316)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.074370 (rank : 314)
Query Neighborhood Hits	146	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CR1_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.137346 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.144903 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.144897 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CRRY_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.119696 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CTRB1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.085494 (rank : 241)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.087873 (rank : 221)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

DAF1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.113892 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	204	Shared Neighborhood Hits	27
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF2_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.112974 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	114	Shared Neighborhood Hits	20
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DESC4_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.094674 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

EDIL3_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.126594 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	292	Shared Neighborhood Hits	18
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.123608 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	317	Shared Neighborhood Hits	16
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFB2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.071476 (rank : 323)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

EGFL7_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.102320 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.069897 (rank : 332)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.088900 (rank : 215)
Query Neighborhood Hits	146	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.093071 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGF_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.069027 (rank : 337)
Query Neighborhood Hits	146	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.077832 (rank : 285)
Query Neighborhood Hits	146	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.075607 (rank : 306)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.084602 (rank : 245)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.086013 (rank : 235)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.082520 (rank : 255)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.075515 (rank : 307)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.075014 (rank : 312)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

EMR1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.069392 (rank : 334)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	33
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.062867 (rank : 371)
Query Neighborhood Hits	146	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.067048 (rank : 346)
Query Neighborhood Hits	146	Target Neighborhood Hits	345	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

F13B_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.095183 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

F13B_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.106803 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FA10_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.116844 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.113579 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.092692 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.090772 (rank : 205)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.097242 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA5_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.111286 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.110907 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.107757 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	374	Shared Neighborhood Hits	26
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA8_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.112312 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.112364 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA9_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.114549 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	421	Shared Neighborhood Hits	29
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.087200 (rank : 225)
Query Neighborhood Hits	146	Target Neighborhood Hits	324	Shared Neighborhood Hits	26
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.085007 (rank : 243)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.087843 (rank : 222)
Query Neighborhood Hits	146	Target Neighborhood Hits	392	Shared Neighborhood Hits	28
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.086917 (rank : 226)
Query Neighborhood Hits	146	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.086344 (rank : 229)
Query Neighborhood Hits	146	Target Neighborhood Hits	293	Shared Neighborhood Hits	22
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.085987 (rank : 236)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.083195 (rank : 252)
Query Neighborhood Hits	146	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.081890 (rank : 264)
Query Neighborhood Hits	146	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.102575 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.101360 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.086284 (rank : 230)
Query Neighborhood Hits	146	Target Neighborhood Hits	557	Shared Neighborhood Hits	29
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.085663 (rank : 239)
Query Neighborhood Hits	146	Target Neighborhood Hits	563	Shared Neighborhood Hits	33
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.082333 (rank : 258)
Query Neighborhood Hits	146	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.082408 (rank : 256)
Query Neighborhood Hits	146	Target Neighborhood Hits	549	Shared Neighborhood Hits	30
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.083989 (rank : 248)
Query Neighborhood Hits	146	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FHR1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.066165 (rank : 353)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR2_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.065964 (rank : 355)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

FHR3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.096527 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.107794 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR5_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.094657 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GAS6_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.089115 (rank : 213)
Query Neighborhood Hits	146	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.083069 (rank : 253)
Query Neighborhood Hits	146	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP2_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.050708 (rank : 413)
Query Neighborhood Hits	146	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

GRAC_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.071573 (rank : 321)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

GRAD_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.068621 (rank : 340)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAE_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.067446 (rank : 344)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAF_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.067508 (rank : 343)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.068747 (rank : 339)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAH_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.078873 (rank : 278)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.070280 (rank : 329)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.077483 (rank : 286)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

HABP2_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.095480 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	431	Shared Neighborhood Hits	24
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.093095 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.094269 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.095132 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.092199 (rank : 190)
Query Neighborhood Hits	146	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.095420 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.076081 (rank : 303)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.076857 (rank : 295)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGF_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.065884 (rank : 358)
Query Neighborhood Hits	146	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.065811 (rank : 360)
Query Neighborhood Hits	146	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.058347 (rank : 392)
Query Neighborhood Hits	146	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPTR_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.132543 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.137387 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.135805 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

K1B11_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.075939 (rank : 304)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B16_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.065011 (rank : 363)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

K1B21_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.073527 (rank : 319)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.075421 (rank : 309)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.074938 (rank : 313)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.071018 (rank : 325)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.073811 (rank : 318)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.078399 (rank : 282)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.075026 (rank : 311)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB4_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.070988 (rank : 326)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

K1KB5_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.075432 (rank : 308)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.070764 (rank : 328)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.078794 (rank : 279)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.079204 (rank : 276)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.078877 (rank : 277)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.076237 (rank : 301)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.080049 (rank : 271)
Query Neighborhood Hits	146	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.079841 (rank : 273)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.082352 (rank : 257)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.077185 (rank : 292)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.071098 (rank : 324)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KLK1_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.077257 (rank : 290)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.073952 (rank : 317)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK3_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.071529 (rank : 322)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

KLK4_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.077152 (rank : 294)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.077246 (rank : 291)
Query Neighborhood Hits	146	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.083863 (rank : 249)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.079498 (rank : 274)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.079867 (rank : 272)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.077295 (rank : 289)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.090164 (rank : 208)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.091275 (rank : 198)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

LDLR_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.111807 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.113009 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	38
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP11_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.068799 (rank : 338)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.062741 (rank : 373)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.103265 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	602	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.101240 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	606	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.095897 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	617	Shared Neighborhood Hits	41
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.121732 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	573	Shared Neighborhood Hits	42
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.107820 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.108506 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.081147 (rank : 266)
Query Neighborhood Hits	146	Target Neighborhood Hits	224	Shared Neighborhood Hits	34
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.075214 (rank : 310)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.091806 (rank : 193)
Query Neighborhood Hits	146	Target Neighborhood Hits	235	Shared Neighborhood Hits	37
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.092470 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.108557 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.112098 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.077357 (rank : 288)
Query Neighborhood Hits	146	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.076092 (rank : 302)
Query Neighborhood Hits	146	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.077159 (rank : 293)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.076308 (rank : 299)
Query Neighborhood Hits	146	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.077415 (rank : 287)
Query Neighborhood Hits	146	Target Neighborhood Hits	552	Shared Neighborhood Hits	30
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.080066 (rank : 270)
Query Neighborhood Hits	146	Target Neighborhood Hits	617	Shared Neighborhood Hits	33
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.078638 (rank : 280)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.091946 (rank : 191)
Query Neighborhood Hits	146	Target Neighborhood Hits	475	Shared Neighborhood Hits	31
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.070019 (rank : 330)
Query Neighborhood Hits	146	Target Neighborhood Hits	607	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.068033 (rank : 342)
Query Neighborhood Hits	146	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.078204 (rank : 283)
Query Neighborhood Hits	146	Target Neighborhood Hits	332	Shared Neighborhood Hits	21
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.129269 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.130378 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	420	Shared Neighborhood Hits	26
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.129279 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	378	Shared Neighborhood Hits	25
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.143290 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAMC2_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.082166 (rank : 261)
Query Neighborhood Hits	146	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.077851 (rank : 284)
Query Neighborhood Hits	146	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MATN1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.063250 (rank : 369)
Query Neighborhood Hits	146	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.060794 (rank : 383)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.092948 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.097915 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	356	Shared Neighborhood Hits	23
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.069969 (rank : 331)
Query Neighborhood Hits	146	Target Neighborhood Hits	268	Shared Neighborhood Hits	23
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.067236 (rank : 345)
Query Neighborhood Hits	146	Target Neighborhood Hits	261	Shared Neighborhood Hits	22
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.089462 (rank : 210)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.086099 (rank : 234)
Query Neighborhood Hits	146	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCPT1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.065003 (rank : 364)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPT1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.069275 (rank : 336)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.070878 (rank : 327)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.066241 (rank : 352)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT5_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.061194 (rank : 381)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

MCPT6_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.086491 (rank : 228)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MCPT8_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.065394 (rank : 362)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

MCPT9_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.064614 (rank : 365)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

MCPTX_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.064032 (rank : 367)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

MCP_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.119928 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MCP_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.130067 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

MEGF6_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.085135 (rank : 242)
Query Neighborhood Hits	146	Target Neighborhood Hits	671	Shared Neighborhood Hits	27
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.050159 (rank : 416)
Query Neighborhood Hits	146	Target Neighborhood Hits	528	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.050309 (rank : 415)
Query Neighborhood Hits	146	Target Neighborhood Hits	520	Shared Neighborhood Hits	26
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEP1A_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.183996 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.181507 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.196792 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.206835 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.153489 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.127104 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NELL1_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.051226 (rank : 412)
Query Neighborhood Hits	146	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.060901 (rank : 382)
Query Neighborhood Hits	146	Target Neighborhood Hits	449	Shared Neighborhood Hits	25
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.059827 (rank : 386)
Query Neighborhood Hits	146	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETR_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.112244 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.110884 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NID1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.050017 (rank : 417)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.053359 (rank : 405)
Query Neighborhood Hits	146	Target Neighborhood Hits	456	Shared Neighborhood Hits	24
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.058456 (rank : 391)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.050476 (rank : 414)
Query Neighborhood Hits	146	Target Neighborhood Hits	1069	Shared Neighborhood Hits	47
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NRPN_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.081920 (rank : 263)
Query Neighborhood Hits	146	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.079408 (rank : 275)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

PAPPA_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.081996 (rank : 262)
Query Neighborhood Hits	146	Target Neighborhood Hits	161	Shared Neighborhood Hits	15
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.085643 (rank : 240)
Query Neighborhood Hits	146	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PERT_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.081782 (rank : 265)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.074267 (rank : 315)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PHXR5_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.084884 (rank : 244)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.090733 (rank : 206)
Query Neighborhood Hits	146	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.092908 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.089444 (rank : 211)
Query Neighborhood Hits	146	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.089190 (rank : 212)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.120495 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.120012 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	426	Shared Neighborhood Hits	27
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.097159 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	340	Shared Neighborhood Hits	28
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.091103 (rank : 200)
Query Neighborhood Hits	146	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.116932 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	422	Shared Neighborhood Hits	27
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.113670 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	410	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.091795 (rank : 194)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.091157 (rank : 199)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.090789 (rank : 203)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.090617 (rank : 207)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

PRTN3_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.057951 (rank : 394)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

PRTN3_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.057146 (rank : 397)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

SORL_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.065888 (rank : 357)
Query Neighborhood Hits	146	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.065644 (rank : 361)
Query Neighborhood Hits	146	Target Neighborhood Hits	439	Shared Neighborhood Hits	24
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SRPX_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.086799 (rank : 227)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.086276 (rank : 231)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SSPO_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.066850 (rank : 349)
Query Neighborhood Hits	146	Target Neighborhood Hits	800	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.057775 (rank : 395)
Query Neighborhood Hits	146	Target Neighborhood Hits	546	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.058866 (rank : 390)
Query Neighborhood Hits	146	Target Neighborhood Hits	566	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SUSD1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.115865 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD2_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.082261 (rank : 260)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.076840 (rank : 296)
Query Neighborhood Hits	146	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD3_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.056197 (rank : 400)
Query Neighborhood Hits	146	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD4_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.100072 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.094919 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

TECTA_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.057441 (rank : 396)
Query Neighborhood Hits	146	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.062431 (rank : 375)
Query Neighborhood Hits	146	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TECTB_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.059491 (rank : 387)
Query Neighborhood Hits	146	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

TECTB_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.061196 (rank : 380)
Query Neighborhood Hits	146	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

TEST_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.092266 (rank : 189)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.093677 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TGBR3_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.056886 (rank : 398)
Query Neighborhood Hits	146	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

THRB_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.107644 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.105780 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TM11D_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.096250 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.095701 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.095869 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.095988 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.102179 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	252	Shared Neighborhood Hits	29
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.101739 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	243	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.094495 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.092453 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	239	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.091086 (rank : 201)
Query Neighborhood Hits	146	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.093174 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.088226 (rank : 217)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.087953 (rank : 219)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS7_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.161534 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.099007 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.095804 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	296	Shared Neighborhood Hits	26
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.090788 (rank : 204)
Query Neighborhood Hits	146	Target Neighborhood Hits	333	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.093532 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.095147 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.100468 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.096236 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.068366 (rank : 341)
Query Neighborhood Hits	146	Target Neighborhood Hits	339	Shared Neighborhood Hits	22
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.066324 (rank : 351)
Query Neighborhood Hits	146	Target Neighborhood Hits	361	Shared Neighborhood Hits	22
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRY1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.083532 (rank : 251)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.085694 (rank : 237)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.084025 (rank : 247)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.083028 (rank : 254)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.084571 (rank : 246)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.086135 (rank : 232)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.087540 (rank : 224)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.086135 (rank : 233)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.083638 (rank : 250)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.093822 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.091870 (rank : 192)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSP3_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.052825 (rank : 407)
Query Neighborhood Hits	146	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.052990 (rank : 406)
Query Neighborhood Hits	146	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP50_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.076432 (rank : 297)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.087803 (rank : 223)
Query Neighborhood Hits	146	Target Neighborhood Hits	272	Shared Neighborhood Hits	23
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.089896 (rank : 209)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.072805 (rank : 320)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.091336 (rank : 197)
Query Neighborhood Hits	146	Target Neighborhood Hits	235	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.076273 (rank : 300)
Query Neighborhood Hits	146	Target Neighborhood Hits	284	Shared Neighborhood Hits	22
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.080172 (rank : 269)
Query Neighborhood Hits	146	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.100884 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.099570 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

XLRS1_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.130267 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.127737 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

ZAN_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.062233 (rank : 377)
Query Neighborhood Hits	146	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZP2_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.069610 (rank : 333)
Query Neighborhood Hits	146	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP2_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.065907 (rank : 356)
Query Neighborhood Hits	146	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP3R_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.130662 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

ZP3_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.054577 (rank : 403)
Query Neighborhood Hits	146	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

ZP4_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.051742 (rank : 410)
Query Neighborhood Hits	146	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

Hits sorted by NC score

PCOC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	146	Target Neighborhood Hits	146	Shared Neighborhood Hits	146
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.992378 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
NC score	0.980857 (rank : 3)	θ value	5.46864e-106 (rank : 4)
Query Neighborhood Hits	146	Target Neighborhood Hits	73	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
NC score	0.979901 (rank : 4)	θ value	4.04623e-109 (rank : 3)
Query Neighborhood Hits	146	Target Neighborhood Hits	73	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL2_MOUSE
NC score	0.822958 (rank : 5)	θ value	1.91475e-42 (rank : 5)
Query Neighborhood Hits	146	Target Neighborhood Hits	240	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.820850 (rank : 6)	θ value	9.50281e-42 (rank : 7)
Query Neighborhood Hits	146	Target Neighborhood Hits	241	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.820245 (rank : 7)	θ value	5.57106e-42 (rank : 6)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.817934 (rank : 8)	θ value	1.2411e-41 (rank : 8)
Query Neighborhood Hits	146	Target Neighborhood Hits	237	Shared Neighborhood Hits	68
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_MOUSE
NC score	0.816334 (rank : 9)	θ value	1.3722e-40 (rank : 9)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.816171 (rank : 10)	θ value	2.34062e-40 (rank : 10)
Query Neighborhood Hits	146	Target Neighborhood Hits	233	Shared Neighborhood Hits	69
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CUZD1_HUMAN
NC score	0.800051 (rank : 11)	θ value	1.16704e-23 (rank : 23)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

MFRP_MOUSE
NC score	0.794315 (rank : 12)	θ value	1.52067e-31 (rank : 17)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO2_HUMAN
NC score	0.789227 (rank : 13)	θ value	6.85773e-16 (rank : 33)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

MFRP_HUMAN
NC score	0.788880 (rank : 14)	θ value	8.3442e-30 (rank : 19)
Query Neighborhood Hits	146	Target Neighborhood Hits	165	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO2_MOUSE
NC score	0.787163 (rank : 15)	θ value	6.85773e-16 (rank : 34)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO1_HUMAN
NC score	0.786539 (rank : 16)	θ value	5.8054e-15 (rank : 36)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.786023 (rank : 17)	θ value	2.20605e-14 (rank : 38)
Query Neighborhood Hits	146	Target Neighborhood Hits	109	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CUZD1_MOUSE
NC score	0.784070 (rank : 18)	θ value	9.24701e-21 (rank : 25)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

NRP2_MOUSE
NC score	0.769586 (rank : 19)	θ value	1.37539e-32 (rank : 16)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.768624 (rank : 20)	θ value	2.77131e-33 (rank : 15)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_HUMAN
NC score	0.760664 (rank : 21)	θ value	1.57e-36 (rank : 11)
Query Neighborhood Hits	146	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
NC score	0.759560 (rank : 22)	θ value	3.86705e-35 (rank : 13)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

TSG6_HUMAN
NC score	0.739207 (rank : 23)	θ value	6.41864e-14 (rank : 39)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.737061 (rank : 24)	θ value	6.41864e-14 (rank : 40)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

PDGFD_HUMAN
NC score	0.699189 (rank : 25)	θ value	2.88788e-06 (rank : 56)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
NC score	0.685001 (rank : 26)	θ value	8.40245e-06 (rank : 58)
Query Neighborhood Hits	146	Target Neighborhood Hits	72	Shared Neighborhood Hits	58
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

CSMD2_HUMAN
NC score	0.673438 (rank : 27)	θ value	3.3877e-31 (rank : 18)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
NC score	0.660257 (rank : 28)	θ value	3.87602e-27 (rank : 20)
Query Neighborhood Hits	146	Target Neighborhood Hits	193	Shared Neighborhood Hits	70
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.657738 (rank : 29)	θ value	1.12775e-26 (rank : 21)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

DMBT1_MOUSE
NC score	0.653758 (rank : 30)	θ value	7.30988e-26 (rank : 22)
Query Neighborhood Hits	146	Target Neighborhood Hits	134	Shared Neighborhood Hits	69
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

CSMD3_HUMAN
NC score	0.651402 (rank : 31)	θ value	1.42661e-21 (rank : 24)
Query Neighborhood Hits	146	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

DCBD1_MOUSE
NC score	0.636078 (rank : 32)	θ value	2.44474e-05 (rank : 59)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.631004 (rank : 33)	θ value	9.26847e-13 (rank : 43)
Query Neighborhood Hits	146	Target Neighborhood Hits	118	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

SEZ6L_HUMAN
NC score	0.624363 (rank : 34)	θ value	1.38499e-08 (rank : 51)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LRP12_MOUSE
NC score	0.622199 (rank : 35)	θ value	2.28291e-11 (rank : 48)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.618219 (rank : 36)	θ value	2.28291e-11 (rank : 47)
Query Neighborhood Hits	146	Target Neighborhood Hits	205	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

DCBD2_MOUSE
NC score	0.612652 (rank : 37)	θ value	7.84624e-12 (rank : 45)
Query Neighborhood Hits	146	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

CUBN_HUMAN
NC score	0.571841 (rank : 38)	θ value	1.32909e-35 (rank : 12)
Query Neighborhood Hits	146	Target Neighborhood Hits	482	Shared Neighborhood Hits	71
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
NC score	0.569073 (rank : 39)	θ value	2.50655e-34 (rank : 14)
Query Neighborhood Hits	146	Target Neighborhood Hits	477	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DMBT1_HUMAN
NC score	0.560307 (rank : 40)	θ value	5.25075e-16 (rank : 31)
Query Neighborhood Hits	146	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DCBD1_HUMAN
NC score	0.548769 (rank : 41)	θ value	1.53129e-07 (rank : 52)
Query Neighborhood Hits	146	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

LRP3_HUMAN
NC score	0.529893 (rank : 42)	θ value	6.64225e-11 (rank : 50)
Query Neighborhood Hits	146	Target Neighborhood Hits	280	Shared Neighborhood Hits	73
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

GP126_HUMAN
NC score	0.480801 (rank : 43)	θ value	4.44505e-15 (rank : 35)
Query Neighborhood Hits	146	Target Neighborhood Hits	187	Shared Neighborhood Hits	65
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

KREM2_HUMAN
NC score	0.476310 (rank : 44)	θ value	1.29631e-06 (rank : 53)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

C1R_HUMAN
NC score	0.469765 (rank : 45)	θ value	4.74913e-17 (rank : 28)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1RA_MOUSE
NC score	0.463765 (rank : 46)	θ value	4.16044e-13 (rank : 42)
Query Neighborhood Hits	146	Target Neighborhood Hits	379	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

KREM1_HUMAN
NC score	0.461799 (rank : 47)	θ value	5.44631e-05 (rank : 60)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

C1RB_MOUSE
NC score	0.457981 (rank : 48)	θ value	3.18553e-13 (rank : 41)
Query Neighborhood Hits	146	Target Neighborhood Hits	380	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

MASP1_HUMAN
NC score	0.453490 (rank : 49)	θ value	1.80466e-16 (rank : 30)
Query Neighborhood Hits	146	Target Neighborhood Hits	369	Shared Neighborhood Hits	68
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP2_HUMAN
NC score	0.451861 (rank : 50)	θ value	5.25075e-16 (rank : 32)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KREM1_MOUSE
NC score	0.449477 (rank : 51)	θ value	5.44631e-05 (rank : 61)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

MASP2_MOUSE
NC score	0.446421 (rank : 52)	θ value	9.90251e-15 (rank : 37)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1S_HUMAN
NC score	0.445977 (rank : 53)	θ value	4.59992e-12 (rank : 44)
Query Neighborhood Hits	146	Target Neighborhood Hits	359	Shared Neighborhood Hits	67
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP1_MOUSE
NC score	0.445836 (rank : 54)	θ value	2.7842e-17 (rank : 27)
Query Neighborhood Hits	146	Target Neighborhood Hits	364	Shared Neighborhood Hits	68
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

CS1A_MOUSE
NC score	0.441371 (rank : 55)	θ value	1.74796e-11 (rank : 46)
Query Neighborhood Hits	146	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.439001 (rank : 56)	θ value	3.89403e-11 (rank : 49)
Query Neighborhood Hits	146	Target Neighborhood Hits	361	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

KREM2_MOUSE
NC score	0.428318 (rank : 57)	θ value	0.000602161 (rank : 63)
Query Neighborhood Hits	146	Target Neighborhood Hits	90	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ST14_HUMAN
NC score	0.354286 (rank : 58)	θ value	1.13037e-18 (rank : 26)
Query Neighborhood Hits	146	Target Neighborhood Hits	409	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
NC score	0.353597 (rank : 59)	θ value	6.20254e-17 (rank : 29)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	69
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ENTK_MOUSE
NC score	0.310828 (rank : 60)	θ value	4.92598e-06 (rank : 57)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ATRN_HUMAN
NC score	0.290029 (rank : 61)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	146	Target Neighborhood Hits	525	Shared Neighborhood Hits	55
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.282935 (rank : 62)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	146	Target Neighborhood Hits	519	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ENTK_HUMAN
NC score	0.276954 (rank : 63)	θ value	0.00102713 (rank : 64)
Query Neighborhood Hits	146	Target Neighborhood Hits	310	Shared Neighborhood Hits	68
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

LRP10_MOUSE
NC score	0.249339 (rank : 64)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	146	Target Neighborhood Hits	169	Shared Neighborhood Hits	41
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SCUB3_MOUSE
NC score	0.248469 (rank : 65)	θ value	1.69304e-06 (rank : 55)
Query Neighborhood Hits	146	Target Neighborhood Hits	442	Shared Neighborhood Hits	66
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.246743 (rank : 66)	θ value	1.29631e-06 (rank : 54)
Query Neighborhood Hits	146	Target Neighborhood Hits	428	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ASTL_MOUSE
NC score	0.214694 (rank : 67)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	146	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

LRP10_HUMAN
NC score	0.213413 (rank : 68)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	146	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ASTL_HUMAN
NC score	0.210689 (rank : 69)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	146	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

MEP1B_MOUSE
NC score	0.206835 (rank : 70)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	146	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1B_HUMAN
NC score	0.196792 (rank : 71)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	146	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1A_HUMAN
NC score	0.183996 (rank : 72)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	146	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
NC score	0.181507 (rank : 73)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	13
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

TMPS7_HUMAN
NC score	0.173297 (rank : 74)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	146	Target Neighborhood Hits	275	Shared Neighborhood Hits	55
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
NC score	0.161534 (rank : 75)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	146	Target Neighborhood Hits	275	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS6_MOUSE
NC score	0.160919 (rank : 76)	θ value	0.000270298 (rank : 62)
Query Neighborhood Hits	146	Target Neighborhood Hits	341	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_HUMAN
NC score	0.159255 (rank : 77)	θ value	0.00390308 (rank : 65)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

C4BB_HUMAN
NC score	0.158600 (rank : 78)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

MFGM_HUMAN
NC score	0.153489 (rank : 79)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	146	Target Neighborhood Hits	150	Shared Neighborhood Hits	9
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

CR2_HUMAN
NC score	0.144903 (rank : 80)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	146	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
NC score	0.144897 (rank : 81)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

LYAM3_MOUSE
NC score	0.143290 (rank : 82)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	146	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

HPT_HUMAN
NC score	0.137387 (rank : 83)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	146	Target Neighborhood Hits	184	Shared Neighborhood Hits	20
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

CR1_HUMAN
NC score	0.137346 (rank : 84)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	146	Target Neighborhood Hits	108	Shared Neighborhood Hits	16
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

HPT_MOUSE
NC score	0.135805 (rank : 85)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

C4BP_MOUSE
NC score	0.133807 (rank : 86)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

HPTR_HUMAN
NC score	0.132543 (rank : 87)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	146	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

CFAB_MOUSE
NC score	0.132211 (rank : 88)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	146	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

C4BP_HUMAN
NC score	0.131569 (rank : 89)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	146	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

APOH_HUMAN
NC score	0.131379 (rank : 90)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CFAB_HUMAN
NC score	0.130971 (rank : 91)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	146	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

ZP3R_MOUSE
NC score	0.130662 (rank : 92)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

LYAM2_MOUSE
NC score	0.130378 (rank : 93)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	146	Target Neighborhood Hits	420	Shared Neighborhood Hits	26
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

XLRS1_HUMAN
NC score	0.130267 (rank : 94)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

MCP_MOUSE
NC score	0.130067 (rank : 95)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	16
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

LYAM3_HUMAN
NC score	0.129279 (rank : 96)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	146	Target Neighborhood Hits	378	Shared Neighborhood Hits	25
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_HUMAN
NC score	0.129269 (rank : 97)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	146	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

XLRS1_MOUSE
NC score	0.127737 (rank : 98)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

CO2_MOUSE
NC score	0.127279 (rank : 99)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	146	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

MFGM_MOUSE
NC score	0.127104 (rank : 100)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	146	Target Neighborhood Hits	233	Shared Neighborhood Hits	10
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

EDIL3_HUMAN
NC score	0.126594 (rank : 101)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	146	Target Neighborhood Hits	292	Shared Neighborhood Hits	18
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CO2_HUMAN
NC score	0.124362 (rank : 102)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	146	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

DAF_HUMAN
NC score	0.124251 (rank : 103)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	146	Target Neighborhood Hits	97	Shared Neighborhood Hits	17
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

EDIL3_MOUSE
NC score	0.123608 (rank : 104)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	146	Target Neighborhood Hits	317	Shared Neighborhood Hits	16
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LRP2_HUMAN
NC score	0.121732 (rank : 105)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	146	Target Neighborhood Hits	573	Shared Neighborhood Hits	42
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PROC_HUMAN
NC score	0.120495 (rank : 106)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	146	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CFAH_HUMAN
NC score	0.120419 (rank : 107)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	146	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAI_MOUSE
NC score	0.120251 (rank : 108)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	146	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

PROC_MOUSE
NC score	0.120012 (rank : 109)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	146	Target Neighborhood Hits	426	Shared Neighborhood Hits	27
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MCP_HUMAN
NC score	0.119928 (rank : 110)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

CRRY_MOUSE
NC score	0.119696 (rank : 111)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CFAH_MOUSE
NC score	0.119070 (rank : 112)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	16
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

APOH_MOUSE
NC score	0.117320 (rank : 113)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

PROZ_HUMAN
NC score	0.116932 (rank : 114)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	146	Target Neighborhood Hits	422	Shared Neighborhood Hits	27
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA10_HUMAN
NC score	0.116844 (rank : 115)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	146	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CFAI_HUMAN
NC score	0.116442 (rank : 116)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	146	Target Neighborhood Hits	289	Shared Neighborhood Hits	30
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

SUSD1_HUMAN
NC score	0.115865 (rank : 117)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	146	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CORIN_HUMAN
NC score	0.114593 (rank : 118)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	146	Target Neighborhood Hits	453	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

FA9_HUMAN
NC score	0.114549 (rank : 119)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	146	Target Neighborhood Hits	421	Shared Neighborhood Hits	29
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

DAF1_MOUSE
NC score	0.113892 (rank : 120)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	146	Target Neighborhood Hits	204	Shared Neighborhood Hits	27
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

PROZ_MOUSE
NC score	0.113670 (rank : 121)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	146	Target Neighborhood Hits	410	Shared Neighborhood Hits	26
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA10_MOUSE
NC score	0.113579 (rank : 122)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	146	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LDLR_MOUSE
NC score	0.113009 (rank : 123)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	38
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

DAF2_MOUSE
NC score	0.112974 (rank : 124)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	146	Target Neighborhood Hits	114	Shared Neighborhood Hits	20
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

CORIN_MOUSE
NC score	0.112439 (rank : 125)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	146	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

FA8_MOUSE
NC score	0.112364 (rank : 126)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	146	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA8_HUMAN
NC score	0.112312 (rank : 127)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	146	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

NETR_HUMAN
NC score	0.112244 (rank : 128)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	146	Target Neighborhood Hits	218	Shared Neighborhood Hits	23
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

LRP8_MOUSE
NC score	0.112098 (rank : 129)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LDLR_HUMAN
NC score	0.111807 (rank : 130)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	146	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FA5_HUMAN
NC score	0.111286 (rank : 131)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA7_HUMAN
NC score	0.110907 (rank : 132)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	146	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

NETR_MOUSE
NC score	0.110884 (rank : 133)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	146	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

LRP8_HUMAN
NC score	0.108557 (rank : 134)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	146	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_MOUSE
NC score	0.108506 (rank : 135)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	146	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP4_HUMAN
NC score	0.107820 (rank : 136)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	146	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

FHR4_HUMAN
NC score	0.107794 (rank : 137)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FA7_MOUSE
NC score	0.107757 (rank : 138)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	146	Target Neighborhood Hits	374	Shared Neighborhood Hits	26
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

THRB_HUMAN
NC score	0.107644 (rank : 139)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	146	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

F13B_MOUSE
NC score	0.106803 (rank : 140)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	146	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

THRB_MOUSE
NC score	0.105780 (rank : 141)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	146	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

LRP1B_HUMAN
NC score	0.103265 (rank : 142)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	146	Target Neighborhood Hits	602	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN5_HUMAN
NC score	0.102575 (rank : 143)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

EGFL7_HUMAN
NC score	0.102320 (rank : 144)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	146	Target Neighborhood Hits	325	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

TMPS2_HUMAN
NC score	0.102179 (rank : 145)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	146	Target Neighborhood Hits	252	Shared Neighborhood Hits	29
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
NC score	0.101739 (rank : 146)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	146	Target Neighborhood Hits	243	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

FBLN5_MOUSE
NC score	0.101360 (rank : 147)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	146	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LRP1B_MOUSE
NC score	0.101240 (rank : 148)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	146	Target Neighborhood Hits	606	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

VLDLR_HUMAN
NC score	0.100884 (rank : 149)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	146	Target Neighborhood Hits	383	Shared Neighborhood Hits	39
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TPA_HUMAN
NC score	0.100468 (rank : 150)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	146	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

SUSD4_HUMAN
NC score	0.100072 (rank : 151)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	146	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

VLDLR_MOUSE
NC score	0.099570 (rank : 152)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	146	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TMPS9_HUMAN
NC score	0.099007 (rank : 153)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	146	Target Neighborhood Hits	276	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

MATN2_MOUSE
NC score	0.097915 (rank : 154)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	146	Target Neighborhood Hits	356	Shared Neighborhood Hits	23
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FA12_HUMAN
NC score	0.097242 (rank : 155)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	146	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PROS_HUMAN
NC score	0.097159 (rank : 156)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	146	Target Neighborhood Hits	340	Shared Neighborhood Hits	28
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

C1QR1_MOUSE
NC score	0.096639 (rank : 157)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	146	Target Neighborhood Hits	342	Shared Neighborhood Hits	27
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

FHR3_HUMAN
NC score	0.096527 (rank : 158)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

TM11D_HUMAN
NC score	0.096250 (rank : 159)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TPA_MOUSE
NC score	0.096236 (rank : 160)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	146	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TM11E_MOUSE
NC score	0.095988 (rank : 161)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

LRP1_HUMAN
NC score	0.095897 (rank : 162)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	146	Target Neighborhood Hits	617	Shared Neighborhood Hits	41
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

TM11E_HUMAN
NC score	0.095869 (rank : 163)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS9_MOUSE
NC score	0.095804 (rank : 164)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	146	Target Neighborhood Hits	296	Shared Neighborhood Hits	26
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TM11D_MOUSE
NC score	0.095701 (rank : 165)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

HABP2_HUMAN
NC score	0.095480 (rank : 166)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	146	Target Neighborhood Hits	431	Shared Neighborhood Hits	24
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_MOUSE
NC score	0.095420 (rank : 167)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	146	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

F13B_HUMAN
NC score	0.095183 (rank : 168)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

TMSP8_MOUSE
NC score	0.095147 (rank : 169)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

HEPS_MOUSE
NC score	0.095132 (rank : 170)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

SUSD4_MOUSE
NC score	0.094919 (rank : 171)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	146	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

DESC4_MOUSE
NC score	0.094674 (rank : 172)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

FHR5_HUMAN
NC score	0.094657 (rank : 173)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	146	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

TMPS3_HUMAN
NC score	0.094495 (rank : 174)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	146	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

HEPS_HUMAN
NC score	0.094269 (rank : 175)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TRYG1_HUMAN
NC score	0.093822 (rank : 176)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TEST_MOUSE
NC score	0.093677 (rank : 177)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TMPSD_MOUSE
NC score	0.093532 (rank : 178)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	146	Target Neighborhood Hits	334	Shared Neighborhood Hits	25
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPS4_MOUSE
NC score	0.093174 (rank : 179)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	146	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

HABP2_MOUSE
NC score	0.093095 (rank : 180)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	146	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

EGFL8_MOUSE
NC score	0.093071 (rank : 181)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	146	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

MATN2_HUMAN
NC score	0.092948 (rank : 182)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	146	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

PLMN_MOUSE
NC score	0.092908 (rank : 183)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	146	Target Neighborhood Hits	208	Shared Neighborhood Hits	21
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

FA11_HUMAN
NC score	0.092692 (rank : 184)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

CD248_MOUSE
NC score	0.092664 (rank : 185)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	146	Target Neighborhood Hits	578	Shared Neighborhood Hits	41
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LRP6_MOUSE
NC score	0.092470 (rank : 186)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	146	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TMPS3_MOUSE
NC score	0.092453 (rank : 187)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	146	Target Neighborhood Hits	239	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

BSSP4_MOUSE
NC score	0.092372 (rank : 188)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TEST_HUMAN
NC score	0.092266 (rank : 189)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

HGFA_HUMAN
NC score	0.092199 (rank : 190)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	146	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LTBP3_MOUSE
NC score	0.091946 (rank : 191)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	146	Target Neighborhood Hits	475	Shared Neighborhood Hits	31
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TRYG1_MOUSE
NC score	0.091870 (rank : 192)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

LRP6_HUMAN
NC score	0.091806 (rank : 193)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	146	Target Neighborhood Hits	235	Shared Neighborhood Hits	37
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

PRS27_HUMAN
NC score	0.091795 (rank : 194)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

BSSP4_HUMAN
NC score	0.091627 (rank : 195)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

ACRO_MOUSE
NC score	0.091419 (rank : 196)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

UROL1_MOUSE
NC score	0.091336 (rank : 197)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	146	Target Neighborhood Hits	235	Shared Neighborhood Hits	22
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

KLKB1_MOUSE
NC score	0.091275 (rank : 198)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

PRS27_MOUSE
NC score	0.091157 (rank : 199)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PROS_MOUSE
NC score	0.091103 (rank : 200)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	146	Target Neighborhood Hits	330	Shared Neighborhood Hits	26
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TMPS4_HUMAN
NC score	0.091086 (rank : 201)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	146	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

ACRO_HUMAN
NC score	0.091012 (rank : 202)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	146	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

PRSS8_HUMAN
NC score	0.090789 (rank : 203)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

TMPSD_HUMAN
NC score	0.090788 (rank : 204)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	146	Target Neighborhood Hits	333	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

FA11_MOUSE
NC score	0.090772 (rank : 205)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

PLMN_HUMAN
NC score	0.090733 (rank : 206)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	146	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PRSS8_MOUSE
NC score	0.090617 (rank : 207)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

KLKB1_HUMAN
NC score	0.090164 (rank : 208)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

UROK_MOUSE
NC score	0.089896 (rank : 209)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	146	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

MATN4_HUMAN
NC score	0.089462 (rank : 210)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

POLS2_HUMAN
NC score	0.089444 (rank : 211)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	146	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
NC score	0.089190 (rank : 212)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

GAS6_HUMAN
NC score	0.089115 (rank : 213)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	146	Target Neighborhood Hits	348	Shared Neighborhood Hits	25
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CLCR_HUMAN
NC score	0.088994 (rank : 214)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

EGFL8_HUMAN
NC score	0.088900 (rank : 215)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	146	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

APOA_HUMAN
NC score	0.088267 (rank : 216)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

TMPS5_HUMAN
NC score	0.088226 (rank : 217)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	146	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

CO6_HUMAN
NC score	0.087965 (rank : 218)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	146	Target Neighborhood Hits	331	Shared Neighborhood Hits	33
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

TMPS5_MOUSE
NC score	0.087953 (rank : 219)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	146	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

CDCP1_HUMAN
NC score	0.087917 (rank : 220)	θ value	0.21417 (rank : 71)
Query Neighborhood Hits	146	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

CTRL_HUMAN
NC score	0.087873 (rank : 221)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

FBLN2_HUMAN
NC score	0.087843 (rank : 222)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	146	Target Neighborhood Hits	392	Shared Neighborhood Hits	28
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

UROK_HUMAN
NC score	0.087803 (rank : 223)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	146	Target Neighborhood Hits	272	Shared Neighborhood Hits	23
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TRYB1_MOUSE
NC score	0.087540 (rank : 224)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

FBLN1_HUMAN
NC score	0.087200 (rank : 225)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	146	Target Neighborhood Hits	324	Shared Neighborhood Hits	26
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_MOUSE
NC score	0.086917 (rank : 226)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	146	Target Neighborhood Hits	505	Shared Neighborhood Hits	35
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SRPX_HUMAN
NC score	0.086799 (rank : 227)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

MCPT6_MOUSE
NC score	0.086491 (rank : 228)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

FBLN3_HUMAN
NC score	0.086344 (rank : 229)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	146	Target Neighborhood Hits	293	Shared Neighborhood Hits	22
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBN1_HUMAN
NC score	0.086284 (rank : 230)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	146	Target Neighborhood Hits	557	Shared Neighborhood Hits	29
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

SRPX_MOUSE
NC score	0.086276 (rank : 231)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	146	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

TRYB1_HUMAN
NC score	0.086135 (rank : 232)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.086135 (rank : 233)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

MATN4_MOUSE
NC score	0.086099 (rank : 234)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	146	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ELA2A_MOUSE
NC score	0.086013 (rank : 235)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

FBLN3_MOUSE
NC score	0.085987 (rank : 236)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	146	Target Neighborhood Hits	279	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

TRY2_HUMAN
NC score	0.085694 (rank : 237)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

CD248_HUMAN
NC score	0.085670 (rank : 238)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	146	Target Neighborhood Hits	679	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FBN1_MOUSE
NC score	0.085663 (rank : 239)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	146	Target Neighborhood Hits	563	Shared Neighborhood Hits	33
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

PAPPA_MOUSE
NC score	0.085643 (rank : 240)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	146	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CTRB1_HUMAN
NC score	0.085494 (rank : 241)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

MEGF6_HUMAN
NC score	0.085135 (rank : 242)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	146	Target Neighborhood Hits	671	Shared Neighborhood Hits	27
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

FBLN1_MOUSE
NC score	0.085007 (rank : 243)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

PHXR5_MOUSE
NC score	0.084884 (rank : 244)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	146	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ELA2A_HUMAN
NC score	0.084602 (rank : 245)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

TRYA1_HUMAN
NC score	0.084571 (rank : 246)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRY2_MOUSE
NC score	0.084025 (rank : 247)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

FBN3_HUMAN
NC score	0.083989 (rank : 248)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	146	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KLK6_HUMAN
NC score	0.083863 (rank : 249)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

TRYD_HUMAN
NC score	0.083638 (rank : 250)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRY1_HUMAN
NC score	0.083532 (rank : 251)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

FBLN4_HUMAN
NC score	0.083195 (rank : 252)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	146	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

GAS6_MOUSE
NC score	0.083069 (rank : 253)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	146	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRY3_HUMAN
NC score	0.083028 (rank : 254)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

ELA2B_HUMAN
NC score	0.082520 (rank : 255)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

FBN2_MOUSE
NC score	0.082408 (rank : 256)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	146	Target Neighborhood Hits	549	Shared Neighborhood Hits	30
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KLK14_HUMAN
NC score	0.082352 (rank : 257)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

FBN2_HUMAN
NC score	0.082333 (rank : 258)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	146	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

CD320_HUMAN
NC score	0.082293 (rank : 259)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	146	Target Neighborhood Hits	103	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

SUSD2_HUMAN
NC score	0.082261 (rank : 260)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	146	Target Neighborhood Hits	99	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

MAMC2_HUMAN
NC score	0.082166 (rank : 261)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	146	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

PAPPA_HUMAN
NC score	0.081996 (rank : 262)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	146	Target Neighborhood Hits	161	Shared Neighborhood Hits	15
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

NRPN_HUMAN
NC score	0.081920 (rank : 263)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	146	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

FBLN4_MOUSE
NC score	0.081890 (rank : 264)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	146	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

PERT_HUMAN
NC score	0.081782 (rank : 265)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LRP5_HUMAN
NC score	0.081147 (rank : 266)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	146	Target Neighborhood Hits	224	Shared Neighborhood Hits	34
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

CFAD_MOUSE
NC score	0.080614 (rank : 267)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAD_HUMAN
NC score	0.080237 (rank : 268)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

UROM_MOUSE
NC score	0.080172 (rank : 269)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	146	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LTBP2_MOUSE
NC score	0.080066 (rank : 270)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	146	Target Neighborhood Hits	617	Shared Neighborhood Hits	33
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KLK12_HUMAN
NC score	0.080049 (rank : 271)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	146	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK7_MOUSE
NC score	0.079867 (rank : 272)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK13_HUMAN
NC score	0.079841 (rank : 273)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK7_HUMAN
NC score	0.079498 (rank : 274)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

NRPN_MOUSE
NC score	0.079408 (rank : 275)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

KLK10_HUMAN
NC score	0.079204 (rank : 276)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
NC score	0.078877 (rank : 277)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

GRAH_HUMAN
NC score	0.078873 (rank : 278)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

K1KB9_MOUSE
NC score	0.078794 (rank : 279)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

LTBP3_HUMAN
NC score	0.078638 (rank : 280)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CATG_MOUSE
NC score	0.078550 (rank : 281)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

K1KB1_MOUSE
NC score	0.078399 (rank : 282)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

LYAM1_MOUSE
NC score	0.078204 (rank : 283)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	146	Target Neighborhood Hits	332	Shared Neighborhood Hits	21
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MAMC2_MOUSE
NC score	0.077851 (rank : 284)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	146	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

EGF_MOUSE
NC score	0.077832 (rank : 285)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	146	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

GRAM_HUMAN
NC score	0.077483 (rank : 286)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

LTBP2_HUMAN
NC score	0.077415 (rank : 287)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	146	Target Neighborhood Hits	552	Shared Neighborhood Hits	30
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1L_HUMAN
NC score	0.077357 (rank : 288)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	146	Target Neighborhood Hits	553	Shared Neighborhood Hits	37
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KLK9_HUMAN
NC score	0.077295 (rank : 289)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLK1_MOUSE
NC score	0.077257 (rank : 290)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK5_HUMAN
NC score	0.077246 (rank : 291)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	146	Target Neighborhood Hits	182	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK15_HUMAN
NC score	0.077185 (rank : 292)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

LTB1S_HUMAN
NC score	0.077159 (rank : 293)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KLK4_HUMAN
NC score	0.077152 (rank : 294)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

HGFL_MOUSE
NC score	0.076857 (rank : 295)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	146	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

SUSD2_MOUSE
NC score	0.076840 (rank : 296)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	146	Target Neighborhood Hits	104	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TSP50_HUMAN
NC score	0.076432 (rank : 297)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

C1QR1_HUMAN
NC score	0.076364 (rank : 298)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	146	Target Neighborhood Hits	493	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LTB1S_MOUSE
NC score	0.076308 (rank : 299)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	146	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

UROM_HUMAN
NC score	0.076273 (rank : 300)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	146	Target Neighborhood Hits	284	Shared Neighborhood Hits	22
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KLK11_MOUSE
NC score	0.076237 (rank : 301)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

LTB1L_MOUSE
NC score	0.076092 (rank : 302)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	146	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

HGFL_HUMAN
NC score	0.076081 (rank : 303)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	146	Target Neighborhood Hits	190	Shared Neighborhood Hits	21
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

K1B11_MOUSE
NC score	0.075939 (rank : 304)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

CATG_HUMAN
NC score	0.075738 (rank : 305)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

ELA1_HUMAN
NC score	0.075607 (rank : 306)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA3A_HUMAN
NC score	0.075515 (rank : 307)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

K1KB5_MOUSE
NC score	0.075432 (rank : 308)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1B22_MOUSE
NC score	0.075421 (rank : 309)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

LRP5_MOUSE
NC score	0.075214 (rank : 310)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	146	Target Neighborhood Hits	236	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

K1KB3_MOUSE
NC score	0.075026 (rank : 311)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

ELA3B_HUMAN
NC score	0.075014 (rank : 312)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

K1B24_MOUSE
NC score	0.074938 (rank : 313)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	146	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

CPXM2_MOUSE
NC score	0.074370 (rank : 314)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	146	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

PERT_MOUSE
NC score	0.074267 (rank : 315)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	146	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CPXM2_HUMAN
NC score	0.074113 (rank : 316)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	146	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

KLK2_HUMAN
NC score	0.073952 (rank : 317)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

K1B27_MOUSE
NC score	0.073811 (rank : 318)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1B21_MOUSE
NC score	0.073527 (rank : 319)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	146	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

UROL1_HUMAN
NC score	0.072805 (rank : 320)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GRAC_MOUSE
NC score	0.071573 (rank : 321)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

KLK3_HUMAN
NC score	0.071529 (rank : 322)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

EGFB2_MOUSE
NC score	0.071476 (rank : 323)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

KLK1_HUMAN
NC score	0.071098 (rank : 324)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

K1B26_MOUSE
NC score	0.071018 (rank : 325)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1KB4_MOUSE
NC score	0.070988 (rank : 326)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

MCPT2_MOUSE
NC score	0.070878 (rank : 327)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

K1KB8_MOUSE
NC score	0.070764 (rank : 328)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

GRAK_MOUSE
NC score	0.070280 (rank : 329)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

LTBP4_MOUSE
NC score	0.070019 (rank : 330)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	146	Target Neighborhood Hits	607	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MATN3_HUMAN
NC score	0.069969 (rank : 331)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	146	Target Neighborhood Hits	268	Shared Neighborhood Hits	23
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

EGFL7_MOUSE
NC score	0.069897 (rank : 332)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	146	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

ZP2_HUMAN
NC score	0.069610 (rank : 333)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	146	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

EMR1_HUMAN
NC score	0.069392 (rank : 334)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	146	Target Neighborhood Hits	382	Shared Neighborhood Hits	33
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CD97_HUMAN
NC score	0.069290 (rank : 335)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	146	Target Neighborhood Hits	353	Shared Neighborhood Hits	26
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

MCPT1_MOUSE
NC score	0.069275 (rank : 336)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

EGF_HUMAN
NC score	0.069027 (rank : 337)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	146	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LRP11_HUMAN
NC score	0.068799 (rank : 338)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

GRAG_MOUSE
NC score	0.068747 (rank : 339)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAD_MOUSE
NC score	0.068621 (rank : 340)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

TRBM_HUMAN
NC score	0.068366 (rank : 341)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	146	Target Neighborhood Hits	339	Shared Neighborhood Hits	22
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LYAM1_HUMAN
NC score	0.068033 (rank : 342)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	146	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

GRAF_MOUSE
NC score	0.067508 (rank : 343)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAE_MOUSE
NC score	0.067446 (rank : 344)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	146	Target Neighborhood Hits	172	Shared Neighborhood Hits	17
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

MATN3_MOUSE
NC score	0.067236 (rank : 345)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	146	Target Neighborhood Hits	261	Shared Neighborhood Hits	22
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

EMR2_HUMAN
NC score	0.067048 (rank : 346)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	146	Target Neighborhood Hits	345	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

C163A_MOUSE
NC score	0.067001 (rank : 347)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	146	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

CAP7_HUMAN
NC score	0.066963 (rank : 348)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	146	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

SSPO_MOUSE
NC score	0.066850 (rank : 349)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	146	Target Neighborhood Hits	800	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

C163A_HUMAN
NC score	0.066685 (rank : 350)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	146	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

TRBM_MOUSE
NC score	0.066324 (rank : 351)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	146	Target Neighborhood Hits	361	Shared Neighborhood Hits	22
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

MCPT4_MOUSE
NC score	0.066241 (rank : 352)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

FHR1_HUMAN
NC score	0.066165 (rank : 353)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	146	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

CNTP2_HUMAN
NC score	0.066149 (rank : 354)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	146	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FHR2_HUMAN
NC score	0.065964 (rank : 355)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

ZP2_MOUSE
NC score	0.065907 (rank : 356)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	146	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

SORL_HUMAN
NC score	0.065888 (rank : 357)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	146	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

HGF_HUMAN
NC score	0.065884 (rank : 358)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	146	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

C163B_HUMAN
NC score	0.065830 (rank : 359)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	146	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

HGF_MOUSE
NC score	0.065811 (rank : 360)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	146	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

SORL_MOUSE
NC score	0.065644 (rank : 361)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	146	Target Neighborhood Hits	439	Shared Neighborhood Hits	24
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

MCPT8_MOUSE
NC score	0.065394 (rank : 362)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

K1B16_MOUSE
NC score	0.065011 (rank : 363)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	146	Target Neighborhood Hits	178	Shared Neighborhood Hits	17
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

MCPT1_HUMAN
NC score	0.065003 (rank : 364)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	146	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPT9_MOUSE
NC score	0.064614 (rank : 365)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

CDCP1_MOUSE
NC score	0.064105 (rank : 366)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	146	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

MCPTX_MOUSE
NC score	0.064032 (rank : 367)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	146	Target Neighborhood Hits	174	Shared Neighborhood Hits	17
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

CPXM1_HUMAN
NC score	0.063654 (rank : 368)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	146	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

MATN1_HUMAN
NC score	0.063250 (rank : 369)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	146	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

CLC14_MOUSE
NC score	0.063002 (rank : 370)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	146	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

EMR1_MOUSE
NC score	0.062867 (rank : 371)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	146	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CNTP3_HUMAN
NC score	0.062746 (rank : 372)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	146	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

LRP11_MOUSE
NC score	0.062741 (rank : 373)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CO7_HUMAN
NC score	0.062740 (rank : 374)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	146	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

TECTA_MOUSE
NC score	0.062431 (rank : 375)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	146	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

CNTP4_MOUSE
NC score	0.062379 (rank : 376)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	146	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

ZAN_MOUSE
NC score	0.062233 (rank : 377)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	146	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CNTP2_MOUSE
NC score	0.062195 (rank : 378)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	146	Target Neighborhood Hits	194	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
NC score	0.061495 (rank : 379)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	146	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TECTB_MOUSE
NC score	0.061196 (rank : 380)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	146	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

MCPT5_MOUSE
NC score	0.061194 (rank : 381)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

NELL2_HUMAN
NC score	0.060901 (rank : 382)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	146	Target Neighborhood Hits	449	Shared Neighborhood Hits	25
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

MATN1_MOUSE
NC score	0.060794 (rank : 383)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	146	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

CPXM1_MOUSE
NC score	0.060182 (rank : 384)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	146	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CD5L_HUMAN
NC score	0.060104 (rank : 385)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	146	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

NELL2_MOUSE
NC score	0.059827 (rank : 386)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	146	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TECTB_HUMAN
NC score	0.059491 (rank : 387)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	146	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

CO9_MOUSE
NC score	0.058888 (rank : 388)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	146	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CLC14_HUMAN
NC score	0.058880 (rank : 389)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	146	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

STAB1_MOUSE
NC score	0.058866 (rank : 390)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	146	Target Neighborhood Hits	566	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NID2_MOUSE
NC score	0.058456 (rank : 391)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	146	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

HMCN1_HUMAN
NC score	0.058347 (rank : 392)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	146	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TGBR3_MOUSE
NC score	0.058074 (rank : 393)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	146	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

PRTN3_HUMAN
NC score	0.057951 (rank : 394)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	146	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

STAB1_HUMAN
NC score	0.057775 (rank : 395)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	146	Target Neighborhood Hits	546	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TECTA_HUMAN
NC score	0.057441 (rank : 396)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	146	Target Neighborhood Hits	239	Shared Neighborhood Hits	17
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

PRTN3_MOUSE
NC score	0.057146 (rank : 397)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	146	Target Neighborhood Hits	177	Shared Neighborhood Hits	17
SwissProt Accessions	Q61096, O08809	Gene names	Prtn3
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Proteinase 3) (PR-3).

TGBR3_HUMAN
NC score	0.056886 (rank : 398)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	146	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

CD5L_MOUSE
NC score	0.056626 (rank : 399)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	146	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

SUSD3_MOUSE
NC score	0.056197 (rank : 400)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	146	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

CD6_HUMAN
NC score	0.056014 (rank : 401)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	146	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CNTP1_MOUSE
NC score	0.055202 (rank : 402)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	146	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

ZP3_HUMAN
NC score	0.054577 (rank : 403)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	146	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

CO9_HUMAN
NC score	0.053633 (rank : 404)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	146	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

NID2_HUMAN
NC score	0.053359 (rank : 405)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	146	Target Neighborhood Hits	456	Shared Neighborhood Hits	24
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TSP3_MOUSE
NC score	0.052990 (rank : 406)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	146	Target Neighborhood Hits	247	Shared Neighborhood Hits	12
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_HUMAN
NC score	0.052825 (rank : 407)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	146	Target Neighborhood Hits	250	Shared Neighborhood Hits	13
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

CD6_MOUSE
NC score	0.052669 (rank : 408)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	146	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

CNTP1_HUMAN
NC score	0.052452 (rank : 409)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	146	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

ZP4_HUMAN
NC score	0.051742 (rank : 410)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	146	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

CD97_MOUSE
NC score	0.051459 (rank : 411)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	146	Target Neighborhood Hits	295	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

NELL1_HUMAN
NC score	0.051226 (rank : 412)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	146	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

GP2_MOUSE
NC score	0.050708 (rank : 413)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	146	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

NOTC2_MOUSE
NC score	0.050476 (rank : 414)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	146	Target Neighborhood Hits	1069	Shared Neighborhood Hits	47
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MEGF8_MOUSE
NC score	0.050309 (rank : 415)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	146	Target Neighborhood Hits	520	Shared Neighborhood Hits	26
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_HUMAN
NC score	0.050159 (rank : 416)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	146	Target Neighborhood Hits	528	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID1_HUMAN
NC score	0.050017 (rank : 417)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	146	Target Neighborhood Hits	329	Shared Neighborhood Hits	22
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

COMP_MOUSE
NC score	0.039206 (rank : 418)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	146	Target Neighborhood Hits	290	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

SETBP_MOUSE
NC score	0.038365 (rank : 419)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	146	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_HUMAN
NC score	0.038189 (rank : 420)	θ value	0.279714 (rank : 73)
Query Neighborhood Hits	146	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SCMH1_MOUSE
NC score	0.029121 (rank : 421)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

DLGP3_HUMAN
NC score	0.028458 (rank : 422)	θ value	0.0736092 (rank : 67)
Query Neighborhood Hits	146	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	O95886, Q5TDD5, Q9H3X7	Gene names	DLGAP3, DAP3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

SCMH1_HUMAN
NC score	0.024606 (rank : 423)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	146	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q96GD3, Q5VT76, Q6IAJ4, Q8WU48, Q9UKM5, Q9UKM6	Gene names	SCMH1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

NET1_HUMAN
NC score	0.024428 (rank : 424)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	146	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

DLGP3_MOUSE
NC score	0.024318 (rank : 425)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	146	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFD5, Q6PDX0, Q6XBF2	Gene names	Dlgap3, Dap3
Domain Architecture	No domain graphic available
Description	Disks large-associated protein 3 (DAP-3) (SAP90/PSD-95-associated protein 3) (SAPAP3) (PSD-95/SAP90-binding protein 3).

NET1_MOUSE
NC score	0.023322 (rank : 426)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	146	Target Neighborhood Hits	151	Shared Neighborhood Hits	5
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NACAM_MOUSE
NC score	0.021650 (rank : 427)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	146	Target Neighborhood Hits	1866	Shared Neighborhood Hits	57
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

OTU7A_MOUSE
NC score	0.021142 (rank : 428)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	146	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

SYN3_MOUSE
NC score	0.020373 (rank : 429)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	146	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

SYN3_HUMAN
NC score	0.019775 (rank : 430)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	146	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	O14994	Gene names	SYN3
Domain Architecture
Description	Synapsin-3 (Synapsin III).

PRRT3_HUMAN
NC score	0.018941 (rank : 431)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	146	Target Neighborhood Hits	998	Shared Neighborhood Hits	47
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SYN2_HUMAN
NC score	0.017777 (rank : 432)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	146	Target Neighborhood Hits	213	Shared Neighborhood Hits	13
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

ATN1_HUMAN
NC score	0.017688 (rank : 433)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	146	Target Neighborhood Hits	676	Shared Neighborhood Hits	16
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CI079_HUMAN
NC score	0.017207 (rank : 434)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	146	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

UBP2L_MOUSE
NC score	0.015753 (rank : 435)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	146	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

CJ047_HUMAN
NC score	0.015416 (rank : 436)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	146	Target Neighborhood Hits	164	Shared Neighborhood Hits	9
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

APXL_HUMAN
NC score	0.014308 (rank : 437)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	146	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

FGFP3_HUMAN
NC score	0.014228 (rank : 438)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	146	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

TAU_MOUSE
NC score	0.014086 (rank : 439)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	146	Target Neighborhood Hits	502	Shared Neighborhood Hits	31
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PCLO_MOUSE
NC score	0.013726 (rank : 440)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	146	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MEF2D_HUMAN
NC score	0.013490 (rank : 441)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	146	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

JADE2_MOUSE
NC score	0.013418 (rank : 442)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	146	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PRP1_HUMAN
NC score	0.013152 (rank : 443)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	146	Target Neighborhood Hits	385	Shared Neighborhood Hits	15
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SHAN2_MOUSE
NC score	0.012922 (rank : 444)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	146	Target Neighborhood Hits	446	Shared Neighborhood Hits	14
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

CSKI1_MOUSE
NC score	0.012730 (rank : 445)	θ value	0.0563607 (rank : 66)
Query Neighborhood Hits	146	Target Neighborhood Hits	1031	Shared Neighborhood Hits	31
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SYAP1_MOUSE
NC score	0.012521 (rank : 446)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	146	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D5V6, Q3UI67, Q9D870	Gene names	Syap1
Domain Architecture
Description	Synapse-associated protein 1.

PACS1_MOUSE
NC score	0.011589 (rank : 447)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	146	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_HUMAN
NC score	0.011322 (rank : 448)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	146	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

CSKI1_HUMAN
NC score	0.011281 (rank : 449)	θ value	0.47712 (rank : 75)
Query Neighborhood Hits	146	Target Neighborhood Hits	997	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SHAN2_HUMAN
NC score	0.011133 (rank : 450)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	146	Target Neighborhood Hits	346	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PRG4_MOUSE
NC score	0.011084 (rank : 451)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	146	Target Neighborhood Hits	624	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TAU_HUMAN
NC score	0.010608 (rank : 452)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	146	Target Neighborhood Hits	448	Shared Neighborhood Hits	19
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

RERE_MOUSE
NC score	0.010515 (rank : 453)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	146	Target Neighborhood Hits	785	Shared Neighborhood Hits	22
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SF01_MOUSE
NC score	0.009990 (rank : 454)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	146	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

TTP_HUMAN
NC score	0.009529 (rank : 455)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	146	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

PCLO_HUMAN
NC score	0.009288 (rank : 456)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	146	Target Neighborhood Hits	2046	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

GPNMB_MOUSE
NC score	0.008988 (rank : 457)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	146	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P91, Q8BVV9, Q8BXL4, Q9QXA0	Gene names	Gpnmb, Dchil, Nmb
Domain Architecture	No domain graphic available
Description	Transmembrane glycoprotein NMB precursor (Dendritic cell-associated transmembrane protein) (DC-HIL).

SAM14_HUMAN
NC score	0.008330 (rank : 458)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	146	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZD0, Q8N2X0	Gene names	SAMD14
Domain Architecture	No domain graphic available
Description	Sterile alpha motif domain-containing protein 14.

SMP1L_HUMAN
NC score	0.008056 (rank : 459)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	146	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

JHD2B_MOUSE
NC score	0.007492 (rank : 460)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	146	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

SFPQ_HUMAN
NC score	0.007336 (rank : 461)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	146	Target Neighborhood Hits	986	Shared Neighborhood Hits	18
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

MLL4_HUMAN
NC score	0.007100 (rank : 462)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	146	Target Neighborhood Hits	722	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SYNJ1_HUMAN
NC score	0.006821 (rank : 463)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	146	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

HCN4_HUMAN
NC score	0.006622 (rank : 464)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	146	Target Neighborhood Hits	303	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SIGIR_MOUSE
NC score	0.006286 (rank : 465)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLZ8, Q52L48	Gene names	Sigirr, Tir8
Domain Architecture	No domain graphic available
Description	Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8).

MINT_MOUSE
NC score	0.006251 (rank : 466)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	146	Target Neighborhood Hits	1514	Shared Neighborhood Hits	41
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CCD96_HUMAN
NC score	0.005620 (rank : 467)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	146	Target Neighborhood Hits	595	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

RTN1_MOUSE
NC score	0.005485 (rank : 468)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	146	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

MUCDL_MOUSE
NC score	0.005354 (rank : 469)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	146	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

AF17_HUMAN
NC score	0.004830 (rank : 470)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	146	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

MILK1_HUMAN
NC score	0.004629 (rank : 471)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	146	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

TAD3L_HUMAN
NC score	0.004452 (rank : 472)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	146	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

ELF1_HUMAN
NC score	0.003965 (rank : 473)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	146	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

BRD4_HUMAN
NC score	0.003213 (rank : 474)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	146	Target Neighborhood Hits	851	Shared Neighborhood Hits	18
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD2AP_MOUSE
NC score	0.002956 (rank : 475)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	146	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

MMP15_HUMAN
NC score	0.002762 (rank : 476)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	146	Target Neighborhood Hits	95	Shared Neighborhood Hits	7
SwissProt Accessions	P51511, Q14111	Gene names	MMP15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP- 2).

MAGI2_HUMAN
NC score	0.002237 (rank : 477)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	146	Target Neighborhood Hits	373	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PRELP_HUMAN
NC score	0.001778 (rank : 478)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	146	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

NMDE4_MOUSE
NC score	0.001589 (rank : 479)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	146	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

ARHGG_HUMAN
NC score	0.001564 (rank : 480)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	146	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CENG1_HUMAN
NC score	0.001553 (rank : 481)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	146	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

DSCL1_HUMAN
NC score	0.000036 (rank : 482)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	146	Target Neighborhood Hits	589	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

WNK2_HUMAN
NC score	-0.001661 (rank : 483)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	146	Target Neighborhood Hits	1407	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZSCA1_HUMAN
NC score	-0.002613 (rank : 484)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	146	Target Neighborhood Hits	724	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NBB4, Q6WLH8, Q86WS8	Gene names	ZSCAN1
Domain Architecture	No domain graphic available
Description	Zinc finger and SCAN domain-containing protein 1.

TITIN_HUMAN
NC score	-0.003303 (rank : 485)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	146	Target Neighborhood Hits	2923	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WNK4_HUMAN
NC score	-0.003994 (rank : 486)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	146	Target Neighborhood Hits	1043	Shared Neighborhood Hits	14
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZN219_HUMAN
NC score	-0.004416 (rank : 487)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	146	Target Neighborhood Hits	876	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2Y4, Q8IYC1, Q9BW28	Gene names	ZNF219
Domain Architecture	No domain graphic available
Description	Zinc finger protein 219.

OBSCN_HUMAN
NC score	-0.004691 (rank : 488)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	146	Target Neighborhood Hits	1931	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ZF276_MOUSE
NC score	-0.004829 (rank : 489)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	146	Target Neighborhood Hits	745	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CE64, Q9ESV2	Gene names	Zfp276
Domain Architecture	No domain graphic available
Description	Zinc finger protein 276 (Zfp-276).

SPEG_HUMAN
NC score	-0.004967 (rank : 490)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	146	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN553_MOUSE
NC score	-0.005096 (rank : 491)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	146	Target Neighborhood Hits	744	Shared Neighborhood Hits	7
SwissProt Accessions	Q3US17, Q3UFP3, Q8R0V0, Q921H7	Gene names	Znf553, Zfp553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

DCAK1_HUMAN
NC score	-0.005807 (rank : 492)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	146	Target Neighborhood Hits	877	Shared Neighborhood Hits	7
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).