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Network neighborhood for query Sequence : FA8_MOUSE

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FA8_MOUSE
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FA8_HUMAN
θ value	0 (rank : 1)	NC score	0.989977 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA5_HUMAN
θ value	1.12453e-151 (rank : 3)	NC score	0.932030 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

HEPH_MOUSE
θ value	7.33985e-127 (rank : 4)	NC score	0.699447 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPH_HUMAN
θ value	7.35691e-119 (rank : 5)	NC score	0.696814 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
θ value	1.53401e-116 (rank : 6)	NC score	0.697488 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CERU_MOUSE
θ value	4.32305e-111 (rank : 7)	NC score	0.695125 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

EDIL3_HUMAN
θ value	3.70236e-70 (rank : 8)	NC score	0.551348 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	8.24801e-70 (rank : 9)	NC score	0.542624 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MFGM_MOUSE
θ value	3.24342e-66 (rank : 10)	NC score	0.666579 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MFGM_HUMAN
θ value	5.92465e-60 (rank : 11)	NC score	0.766711 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NRP2_MOUSE
θ value	2.11701e-41 (rank : 12)	NC score	0.539585 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
θ value	4.71619e-41 (rank : 13)	NC score	0.532854 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	6.15952e-41 (rank : 14)	NC score	0.537107 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_HUMAN
θ value	1.08726e-37 (rank : 15)	NC score	0.529884 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DCBD2_HUMAN
θ value	3.87602e-27 (rank : 16)	NC score	0.576101 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	1.62847e-25 (rank : 17)	NC score	0.587725 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
θ value	4.43474e-23 (rank : 18)	NC score	0.586888 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CPXM2_MOUSE
θ value	1.29031e-22 (rank : 19)	NC score	0.482075 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
θ value	4.9032e-22 (rank : 20)	NC score	0.479324 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

XLRS1_MOUSE
θ value	2.06002e-20 (rank : 21)	NC score	0.729120 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
θ value	7.82807e-20 (rank : 22)	NC score	0.728251 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

CPXM1_MOUSE
θ value	1.38178e-16 (rank : 23)	NC score	0.435240 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP2_HUMAN
θ value	5.25075e-16 (rank : 24)	NC score	0.461825 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CPXM1_HUMAN
θ value	1.52774e-15 (rank : 25)	NC score	0.442625 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP4_MOUSE
θ value	1.68911e-14 (rank : 26)	NC score	0.444602 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP2_MOUSE
θ value	2.20605e-14 (rank : 27)	NC score	0.449439 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
θ value	2.88119e-14 (rank : 28)	NC score	0.441851 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP3_HUMAN
θ value	6.41864e-14 (rank : 29)	NC score	0.452176 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP1_HUMAN
θ value	4.59992e-12 (rank : 30)	NC score	0.420260 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DDR2_MOUSE
θ value	4.59992e-12 (rank : 31)	NC score	0.161934 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_HUMAN
θ value	1.33837e-11 (rank : 32)	NC score	0.160189 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

CNTP1_MOUSE
θ value	2.28291e-11 (rank : 33)	NC score	0.418377 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DDR1_HUMAN
θ value	5.08577e-11 (rank : 34)	NC score	0.148327 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	3.29651e-10 (rank : 35)	NC score	0.141448 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

SMC4_MOUSE
θ value	1.87187e-05 (rank : 36)	NC score	0.043829 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	830	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

SMC4_HUMAN
θ value	0.00509761 (rank : 37)	NC score	0.036384 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	937	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

CCD46_HUMAN
θ value	0.0563607 (rank : 38)	NC score	0.013908 (rank : 122)
Query Neighborhood Hits	100	Target Neighborhood Hits	1430	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RIF1_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.028172 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SSPO_MOUSE
θ value	0.125558 (rank : 40)	NC score	0.046316 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

UBP2L_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.054557 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

NRIP1_MOUSE
θ value	0.163984 (rank : 42)	NC score	0.033699 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

TERF2_MOUSE
θ value	0.21417 (rank : 43)	NC score	0.037582 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

CALB2_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.040531 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

KMHN1_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.018139 (rank : 113)
Query Neighborhood Hits	100	Target Neighborhood Hits	950	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

UBP2L_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.050703 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

CALB2_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.039479 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

XTP3B_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.036085 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DZ1, O95901, Q6UWN7, Q9NUY7, Q9UQL4	Gene names	C2orf30, XTP3TPB
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein precursor.

AKAP5_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.035465 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

GCC2_HUMAN
θ value	0.62314 (rank : 50)	NC score	0.016979 (rank : 116)
Query Neighborhood Hits	100	Target Neighborhood Hits	1558	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.016989 (rank : 115)
Query Neighborhood Hits	100	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

XTP3B_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.035043 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEH8, Q3UZF3, Q8BVN6	Gene names
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein homolog precursor.

TBCD1_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.014642 (rank : 121)
Query Neighborhood Hits	100	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

ANR18_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.008881 (rank : 132)
Query Neighborhood Hits	100	Target Neighborhood Hits	1106	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

DPOLZ_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.015808 (rank : 118)
Query Neighborhood Hits	100	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

MNT_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.020012 (rank : 110)
Query Neighborhood Hits	100	Target Neighborhood Hits	496	Shared Neighborhood Hits	8
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

CA026_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.018101 (rank : 114)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CLSPN_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.016538 (rank : 117)
Query Neighborhood Hits	100	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

TARA_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.012817 (rank : 123)
Query Neighborhood Hits	100	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BRDT_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.010617 (rank : 129)
Query Neighborhood Hits	100	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

DHX30_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.011259 (rank : 128)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.011304 (rank : 127)
Query Neighborhood Hits	100	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

KMHN1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.015182 (rank : 120)
Query Neighborhood Hits	100	Target Neighborhood Hits	949	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

MNT_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.018848 (rank : 111)
Query Neighborhood Hits	100	Target Neighborhood Hits	432	Shared Neighborhood Hits	8
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RIN3_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.011965 (rank : 125)
Query Neighborhood Hits	100	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TERF1_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.025412 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

TF3C1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.015562 (rank : 119)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

K0082_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.020479 (rank : 108)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

K1C13_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.003802 (rank : 147)
Query Neighborhood Hits	100	Target Neighborhood Hits	386	Shared Neighborhood Hits	13
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

TERF2_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.039225 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TOM70_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.018813 (rank : 112)
Query Neighborhood Hits	100	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.020057 (rank : 109)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

CP250_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.006696 (rank : 139)
Query Neighborhood Hits	100	Target Neighborhood Hits	1583	Shared Neighborhood Hits	22
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ESCO1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.012592 (rank : 124)
Query Neighborhood Hits	100	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

MAP1B_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.011904 (rank : 126)
Query Neighborhood Hits	100	Target Neighborhood Hits	977	Shared Neighborhood Hits	25
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PLK4_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.002894 (rank : 151)
Query Neighborhood Hits	100	Target Neighborhood Hits	879	Shared Neighborhood Hits	6
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

SRGP2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.005309 (rank : 144)
Query Neighborhood Hits	100	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ZHX1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.006532 (rank : 140)
Query Neighborhood Hits	100	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

CP135_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.008905 (rank : 131)
Query Neighborhood Hits	100	Target Neighborhood Hits	1290	Shared Neighborhood Hits	26
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GOGA5_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.006521 (rank : 141)
Query Neighborhood Hits	100	Target Neighborhood Hits	1434	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

ICOSL_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.009109 (rank : 130)
Query Neighborhood Hits	100	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

NRIP1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.023258 (rank : 107)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

REST_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.006775 (rank : 138)
Query Neighborhood Hits	100	Target Neighborhood Hits	1605	Shared Neighborhood Hits	24
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

K1C13_MOUSE
θ value	6.88961 (rank : 84)	NC score	0.003298 (rank : 150)
Query Neighborhood Hits	100	Target Neighborhood Hits	410	Shared Neighborhood Hits	15
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

KIF3B_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.003522 (rank : 149)
Query Neighborhood Hits	100	Target Neighborhood Hits	533	Shared Neighborhood Hits	15
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

RN168_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.004314 (rank : 145)
Query Neighborhood Hits	100	Target Neighborhood Hits	370	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TM117_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.033195 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH18, Q8C6X8	Gene names	Tmem117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

ZBT7B_HUMAN
θ value	6.88961 (rank : 88)	NC score	-0.004187 (rank : 154)
Query Neighborhood Hits	100	Target Neighborhood Hits	796	Shared Neighborhood Hits	3
SwissProt Accessions	O15156, Q68DR2, Q96EP2	Gene names	ZBTB7B, ZBTB15, ZFP67
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 7B (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein Th-POK) (T-helper-inducing POZ/Krueppel-like factor) (Krueppel-related zinc finger protein cKrox) (hcKrox) (Zinc finger and BTB domain-containing protein 15).

ZN578_HUMAN
θ value	6.88961 (rank : 89)	NC score	-0.004489 (rank : 155)
Query Neighborhood Hits	100	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.

CP250_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.005584 (rank : 142)
Query Neighborhood Hits	100	Target Neighborhood Hits	1805	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GAB1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.005335 (rank : 143)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GFAP_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.003951 (rank : 146)
Query Neighborhood Hits	100	Target Neighborhood Hits	725	Shared Neighborhood Hits	22
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

PHF3_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.007223 (rank : 136)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	11
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PLD1_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.008229 (rank : 133)
Query Neighborhood Hits	100	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.008166 (rank : 134)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PODXL_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.007367 (rank : 135)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

SPB12_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.000498 (rank : 153)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

TIAM1_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.002514 (rank : 152)
Query Neighborhood Hits	100	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TRPM6_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.003533 (rank : 148)
Query Neighborhood Hits	100	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TTC4_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.007019 (rank : 137)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

AGRIN_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.064007 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	582	Shared Neighborhood Hits	12
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.075857 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.075747 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CBPD_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.087576 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.087566 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPE_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.101604 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.101487 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPM_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.091017 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.091368 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPN_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.099891 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.100235 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPZ_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.089221 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.090574 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CRUM1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.051716 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.052456 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSMD1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.052666 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.052321 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.056301 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.053220 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.087115 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	482	Shared Neighborhood Hits	20
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.087610 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.087792 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.082402 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.157882 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DMBT1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.065125 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

GLPC_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.099204 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

GP126_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.054820 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.056176 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.058237 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

MAMC2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.068641 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.063999 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MFRP_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.079951 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.081092 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.095723 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.098321 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.101660 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.099674 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRX1A_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.090912 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.089870 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.077069 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.087718 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PCOC1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.112364 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.114208 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.111528 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.114280 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.088712 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.074897 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.060786 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.053035 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

TLL1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.074952 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.074081 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.074937 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.075473 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TSG6_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.096279 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.096797 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

Hits sorted by NC score

FA8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA8_HUMAN
NC score	0.989977 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA5_HUMAN
NC score	0.932030 (rank : 3)	θ value	1.12453e-151 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MFGM_HUMAN
NC score	0.766711 (rank : 4)	θ value	5.92465e-60 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

XLRS1_MOUSE
NC score	0.729120 (rank : 5)	θ value	2.06002e-20 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
NC score	0.728251 (rank : 6)	θ value	7.82807e-20 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

HEPH_MOUSE
NC score	0.699447 (rank : 7)	θ value	7.33985e-127 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
NC score	0.697488 (rank : 8)	θ value	1.53401e-116 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
NC score	0.696814 (rank : 9)	θ value	7.35691e-119 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_MOUSE
NC score	0.695125 (rank : 10)	θ value	4.32305e-111 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

MFGM_MOUSE
NC score	0.666579 (rank : 11)	θ value	3.24342e-66 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

DCBD2_MOUSE
NC score	0.587725 (rank : 12)	θ value	1.62847e-25 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
NC score	0.586888 (rank : 13)	θ value	4.43474e-23 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.576101 (rank : 14)	θ value	3.87602e-27 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

EDIL3_HUMAN
NC score	0.551348 (rank : 15)	θ value	3.70236e-70 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.542624 (rank : 16)	θ value	8.24801e-70 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NRP2_MOUSE
NC score	0.539585 (rank : 17)	θ value	2.11701e-41 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.537107 (rank : 18)	θ value	6.15952e-41 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
NC score	0.532854 (rank : 19)	θ value	4.71619e-41 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.529884 (rank : 20)	θ value	1.08726e-37 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CPXM2_MOUSE
NC score	0.482075 (rank : 21)	θ value	1.29031e-22 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
NC score	0.479324 (rank : 22)	θ value	4.9032e-22 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CNTP2_HUMAN
NC score	0.461825 (rank : 23)	θ value	5.25075e-16 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
NC score	0.452176 (rank : 24)	θ value	6.41864e-14 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP2_MOUSE
NC score	0.449439 (rank : 25)	θ value	2.20605e-14 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_MOUSE
NC score	0.444602 (rank : 26)	θ value	1.68911e-14 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CPXM1_HUMAN
NC score	0.442625 (rank : 27)	θ value	1.52774e-15 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP4_HUMAN
NC score	0.441851 (rank : 28)	θ value	2.88119e-14 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CPXM1_MOUSE
NC score	0.435240 (rank : 29)	θ value	1.38178e-16 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP1_HUMAN
NC score	0.420260 (rank : 30)	θ value	4.59992e-12 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
NC score	0.418377 (rank : 31)	θ value	2.28291e-11 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DDR2_MOUSE
NC score	0.161934 (rank : 32)	θ value	4.59992e-12 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_HUMAN
NC score	0.160189 (rank : 33)	θ value	1.33837e-11 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DCBD1_MOUSE
NC score	0.157882 (rank : 34)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DDR1_HUMAN
NC score	0.148327 (rank : 35)	θ value	5.08577e-11 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
NC score	0.141448 (rank : 36)	θ value	3.29651e-10 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

PCOC2_MOUSE
NC score	0.114280 (rank : 37)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	100	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.114208 (rank : 38)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.112364 (rank : 39)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	100	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC2_HUMAN
NC score	0.111528 (rank : 40)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	100	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

NETO2_HUMAN
NC score	0.101660 (rank : 41)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CBPE_HUMAN
NC score	0.101604 (rank : 42)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_MOUSE
NC score	0.101487 (rank : 43)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	100	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPN_MOUSE
NC score	0.100235 (rank : 44)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	100	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPN_HUMAN
NC score	0.099891 (rank : 45)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	100	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

NETO2_MOUSE
NC score	0.099674 (rank : 46)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	100	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

GLPC_HUMAN
NC score	0.099204 (rank : 47)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	100	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

NETO1_MOUSE
NC score	0.098321 (rank : 48)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	100	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TSG6_MOUSE
NC score	0.096797 (rank : 49)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.096279 (rank : 50)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NETO1_HUMAN
NC score	0.095723 (rank : 51)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CBPM_MOUSE
NC score	0.091368 (rank : 52)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	100	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_HUMAN
NC score	0.091017 (rank : 53)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	100	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

NRX1A_HUMAN
NC score	0.090912 (rank : 54)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CBPZ_MOUSE
NC score	0.090574 (rank : 55)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	100	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

NRX1A_MOUSE
NC score	0.089870 (rank : 56)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	100	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CBPZ_HUMAN
NC score	0.089221 (rank : 57)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

PDGFD_HUMAN
NC score	0.088712 (rank : 58)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	100	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

CUZD1_HUMAN
NC score	0.087792 (rank : 59)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	100	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

NRX3A_HUMAN
NC score	0.087718 (rank : 60)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	100	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CUBN_MOUSE
NC score	0.087610 (rank : 61)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	100	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CBPD_HUMAN
NC score	0.087576 (rank : 62)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.087566 (rank : 63)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CUBN_HUMAN
NC score	0.087115 (rank : 64)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	100	Target Neighborhood Hits	482	Shared Neighborhood Hits	20
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUZD1_MOUSE
NC score	0.082402 (rank : 65)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	100	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

MFRP_MOUSE
NC score	0.081092 (rank : 66)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	100	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.079951 (rank : 67)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	100	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NRX2A_HUMAN
NC score	0.077069 (rank : 68)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	100	Target Neighborhood Hits	614	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

BMP1_HUMAN
NC score	0.075857 (rank : 69)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
NC score	0.075747 (rank : 70)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.075473 (rank : 71)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	100	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.074952 (rank : 72)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	100	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.074937 (rank : 73)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	100	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PDGFD_MOUSE
NC score	0.074897 (rank : 74)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	100	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

TLL1_MOUSE
NC score	0.074081 (rank : 75)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	100	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

MAMC2_HUMAN
NC score	0.068641 (rank : 76)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	100	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

DMBT1_MOUSE
NC score	0.065125 (rank : 77)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

AGRIN_HUMAN
NC score	0.064007 (rank : 78)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	582	Shared Neighborhood Hits	12
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

MAMC2_MOUSE
NC score	0.063999 (rank : 79)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	100	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

SEZ6L_HUMAN
NC score	0.060786 (rank : 80)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	100	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LRP12_MOUSE
NC score	0.058237 (rank : 81)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	100	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CSMD2_HUMAN
NC score	0.056301 (rank : 82)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

LRP12_HUMAN
NC score	0.056176 (rank : 83)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	100	Target Neighborhood Hits	205	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

GP126_HUMAN
NC score	0.054820 (rank : 84)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	100	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

UBP2L_MOUSE
NC score	0.054557 (rank : 85)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

CSMD3_HUMAN
NC score	0.053220 (rank : 86)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	100	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

SHBG_HUMAN
NC score	0.053035 (rank : 87)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	100	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

CSMD1_HUMAN
NC score	0.052666 (rank : 88)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	100	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CRUM1_MOUSE
NC score	0.052456 (rank : 89)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	100	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSMD1_MOUSE
NC score	0.052321 (rank : 90)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	100	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CRUM1_HUMAN
NC score	0.051716 (rank : 91)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	100	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

UBP2L_HUMAN
NC score	0.050703 (rank : 92)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

SSPO_MOUSE
NC score	0.046316 (rank : 93)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SMC4_MOUSE
NC score	0.043829 (rank : 94)	θ value	1.87187e-05 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	830	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CALB2_MOUSE
NC score	0.040531 (rank : 95)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	141	Shared Neighborhood Hits	4
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALB2_HUMAN
NC score	0.039479 (rank : 96)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

TERF2_HUMAN
NC score	0.039225 (rank : 97)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TERF2_MOUSE
NC score	0.037582 (rank : 98)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	128	Shared Neighborhood Hits	7
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

SMC4_HUMAN
NC score	0.036384 (rank : 99)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	937	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

XTP3B_HUMAN
NC score	0.036085 (rank : 100)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DZ1, O95901, Q6UWN7, Q9NUY7, Q9UQL4	Gene names	C2orf30, XTP3TPB
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein precursor.

AKAP5_HUMAN
NC score	0.035465 (rank : 101)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P24588	Gene names	AKAP5, AKAP79
Domain Architecture
Description	A-kinase anchor protein 5 (A-kinase anchor protein 79 kDa) (AKAP 79) (cAMP-dependent protein kinase regulatory subunit II high affinity- binding protein) (H21).

XTP3B_MOUSE
NC score	0.035043 (rank : 102)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEH8, Q3UZF3, Q8BVN6	Gene names
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein homolog precursor.

NRIP1_MOUSE
NC score	0.033699 (rank : 103)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

TM117_MOUSE
NC score	0.033195 (rank : 104)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH18, Q8C6X8	Gene names	Tmem117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

RIF1_HUMAN
NC score	0.028172 (rank : 105)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

TERF1_HUMAN
NC score	0.025412 (rank : 106)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

NRIP1_HUMAN
NC score	0.023258 (rank : 107)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

K0082_HUMAN
NC score	0.020479 (rank : 108)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

TOM70_MOUSE
NC score	0.020057 (rank : 109)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

MNT_HUMAN
NC score	0.020012 (rank : 110)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	496	Shared Neighborhood Hits	8
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
NC score	0.018848 (rank : 111)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	432	Shared Neighborhood Hits	8
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TOM70_HUMAN
NC score	0.018813 (rank : 112)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

KMHN1_HUMAN
NC score	0.018139 (rank : 113)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	950	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

CA026_MOUSE
NC score	0.018101 (rank : 114)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

RBP24_HUMAN
NC score	0.016989 (rank : 115)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	1559	Shared Neighborhood Hits	28
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.016979 (rank : 116)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	1558	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CLSPN_MOUSE
NC score	0.016538 (rank : 117)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

DPOLZ_HUMAN
NC score	0.015808 (rank : 118)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

TF3C1_HUMAN
NC score	0.015562 (rank : 119)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

KMHN1_MOUSE
NC score	0.015182 (rank : 120)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	949	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

TBCD1_HUMAN
NC score	0.014642 (rank : 121)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	276	Shared Neighborhood Hits	12
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

CCD46_HUMAN
NC score	0.013908 (rank : 122)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	1430	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TARA_MOUSE
NC score	0.012817 (rank : 123)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ESCO1_HUMAN
NC score	0.012592 (rank : 124)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	361	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RIN3_MOUSE
NC score	0.011965 (rank : 125)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MAP1B_MOUSE
NC score	0.011904 (rank : 126)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	977	Shared Neighborhood Hits	25
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

DHX30_MOUSE
NC score	0.011304 (rank : 127)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

DHX30_HUMAN
NC score	0.011259 (rank : 128)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

BRDT_HUMAN
NC score	0.010617 (rank : 129)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

ICOSL_HUMAN
NC score	0.009109 (rank : 130)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

CP135_HUMAN
NC score	0.008905 (rank : 131)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	1290	Shared Neighborhood Hits	26
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

ANR18_HUMAN
NC score	0.008881 (rank : 132)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	1106	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

PLD1_HUMAN
NC score	0.008229 (rank : 133)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
NC score	0.008166 (rank : 134)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

PODXL_MOUSE
NC score	0.007367 (rank : 135)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0M4, Q9ESZ1	Gene names	Podxl, Pclp1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

PHF3_HUMAN
NC score	0.007223 (rank : 136)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	11
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TTC4_HUMAN
NC score	0.007019 (rank : 137)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

REST_HUMAN
NC score	0.006775 (rank : 138)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	1605	Shared Neighborhood Hits	24
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CP250_MOUSE
NC score	0.006696 (rank : 139)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	1583	Shared Neighborhood Hits	22
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

ZHX1_HUMAN
NC score	0.006532 (rank : 140)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

GOGA5_MOUSE
NC score	0.006521 (rank : 141)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	1434	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CP250_HUMAN
NC score	0.005584 (rank : 142)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	1805	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GAB1_MOUSE
NC score	0.005335 (rank : 143)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

SRGP2_HUMAN
NC score	0.005309 (rank : 144)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RN168_HUMAN
NC score	0.004314 (rank : 145)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	370	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

GFAP_MOUSE
NC score	0.003951 (rank : 146)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	725	Shared Neighborhood Hits	22
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

K1C13_HUMAN
NC score	0.003802 (rank : 147)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	386	Shared Neighborhood Hits	13
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

TRPM6_MOUSE
NC score	0.003533 (rank : 148)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

KIF3B_MOUSE
NC score	0.003522 (rank : 149)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	533	Shared Neighborhood Hits	15
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

K1C13_MOUSE
NC score	0.003298 (rank : 150)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	410	Shared Neighborhood Hits	15
SwissProt Accessions	P08730, Q3V176, Q6PAI1	Gene names	Krt13, Krt1-13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13) (47 kDa cytokeratin).

PLK4_MOUSE
NC score	0.002894 (rank : 151)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	879	Shared Neighborhood Hits	6
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

TIAM1_HUMAN
NC score	0.002514 (rank : 152)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

SPB12_MOUSE
NC score	0.000498 (rank : 153)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7P9, Q6UKZ3	Gene names	Serpinb12
Domain Architecture	No domain graphic available
Description	Serpin B12.

ZBT7B_HUMAN
NC score	-0.004187 (rank : 154)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	796	Shared Neighborhood Hits	3
SwissProt Accessions	O15156, Q68DR2, Q96EP2	Gene names	ZBTB7B, ZBTB15, ZFP67
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 7B (Zinc finger protein 67 homolog) (Zfp-67) (Zinc finger protein Th-POK) (T-helper-inducing POZ/Krueppel-like factor) (Krueppel-related zinc finger protein cKrox) (hcKrox) (Zinc finger and BTB domain-containing protein 15).

ZN578_HUMAN
NC score	-0.004489 (rank : 155)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.