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Network neighborhood for query Sequence : SEZ6L_HUMAN

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SEZ6L_HUMAN
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEZ6L_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD2_HUMAN
θ value	2.3998e-69 (rank : 2)	NC score	0.898829 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
θ value	4.09345e-69 (rank : 3)	NC score	0.897567 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	119
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
θ value	2.03155e-68 (rank : 4)	NC score	0.899998 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	117
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
θ value	3.14151e-61 (rank : 5)	NC score	0.900445 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

TLL2_MOUSE
θ value	2.59989e-23 (rank : 6)	NC score	0.616766 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_HUMAN
θ value	1.29031e-22 (rank : 7)	NC score	0.613417 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	241	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CR2_MOUSE
θ value	4.9032e-22 (rank : 8)	NC score	0.704833 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

TLL1_HUMAN
θ value	8.36355e-22 (rank : 9)	NC score	0.611791 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	73
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	2.69047e-20 (rank : 10)	NC score	0.610840 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	237	Shared Neighborhood Hits	74
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

CR1_HUMAN
θ value	5.99374e-20 (rank : 11)	NC score	0.693852 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

MASP1_HUMAN
θ value	5.99374e-20 (rank : 12)	NC score	0.417343 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	369	Shared Neighborhood Hits	108
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

BMP1_HUMAN
θ value	7.82807e-20 (rank : 13)	NC score	0.608267 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	73
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	6.62687e-19 (rank : 14)	NC score	0.607626 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	73
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CR2_HUMAN
θ value	1.058e-16 (rank : 15)	NC score	0.699298 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

DAF_HUMAN
θ value	1.38178e-16 (rank : 16)	NC score	0.678097 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	97	Shared Neighborhood Hits	67
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

C4BB_HUMAN
θ value	4.02038e-16 (rank : 17)	NC score	0.718077 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

LYAM3_MOUSE
θ value	5.25075e-16 (rank : 18)	NC score	0.583015 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	390	Shared Neighborhood Hits	84
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

F13B_MOUSE
θ value	8.95645e-16 (rank : 19)	NC score	0.639402 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

C4BP_HUMAN
θ value	1.16975e-15 (rank : 20)	NC score	0.691474 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	67
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

MASP1_MOUSE
θ value	1.52774e-15 (rank : 21)	NC score	0.405972 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	104
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_MOUSE
θ value	1.99529e-15 (rank : 22)	NC score	0.432070 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	109
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CUBN_MOUSE
θ value	4.44505e-15 (rank : 23)	NC score	0.419622 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

C4BP_MOUSE
θ value	9.90251e-15 (rank : 24)	NC score	0.696881 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

ZP3R_MOUSE
θ value	9.90251e-15 (rank : 25)	NC score	0.685870 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CFAH_HUMAN
θ value	2.20605e-14 (rank : 26)	NC score	0.636510 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

F13B_HUMAN
θ value	2.20605e-14 (rank : 27)	NC score	0.625782 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

NRP2_MOUSE
θ value	4.91457e-14 (rank : 28)	NC score	0.528066 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MASP2_HUMAN
θ value	6.41864e-14 (rank : 29)	NC score	0.422197 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	106
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CS1A_MOUSE
θ value	8.38298e-14 (rank : 30)	NC score	0.411129 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	360	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

NRP2_HUMAN
θ value	8.38298e-14 (rank : 31)	NC score	0.525433 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CS1B_MOUSE
θ value	4.16044e-13 (rank : 32)	NC score	0.409417 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LYAM3_HUMAN
θ value	4.16044e-13 (rank : 33)	NC score	0.575886 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	378	Shared Neighborhood Hits	83
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

DAF1_MOUSE
θ value	5.43371e-13 (rank : 34)	NC score	0.648158 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	92
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MCP_HUMAN
θ value	5.43371e-13 (rank : 35)	NC score	0.673611 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

LYAM2_HUMAN
θ value	1.58096e-12 (rank : 36)	NC score	0.555087 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CRRY_MOUSE
θ value	2.69671e-12 (rank : 37)	NC score	0.677431 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

LYAM2_MOUSE
θ value	3.52202e-12 (rank : 38)	NC score	0.553050 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	420	Shared Neighborhood Hits	85
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CUBN_HUMAN
θ value	4.59992e-12 (rank : 39)	NC score	0.428236 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	482	Shared Neighborhood Hits	85
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DAF2_MOUSE
θ value	4.59992e-12 (rank : 40)	NC score	0.649964 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

C1S_HUMAN
θ value	6.00763e-12 (rank : 41)	NC score	0.425447 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	359	Shared Neighborhood Hits	104
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MFRP_MOUSE
θ value	6.00763e-12 (rank : 42)	NC score	0.554606 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CFAH_MOUSE
θ value	5.08577e-11 (rank : 43)	NC score	0.635581 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	67
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

MCP_MOUSE
θ value	1.25267e-09 (rank : 44)	NC score	0.663694 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

APOH_HUMAN
θ value	2.13673e-09 (rank : 45)	NC score	0.660749 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

APOH_MOUSE
θ value	2.13673e-09 (rank : 46)	NC score	0.652170 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

NRP1_MOUSE
θ value	2.13673e-09 (rank : 47)	NC score	0.503594 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

FHR3_HUMAN
θ value	2.79066e-09 (rank : 48)	NC score	0.545773 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

PCOC2_HUMAN
θ value	8.11959e-09 (rank : 49)	NC score	0.615881 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

CUZD1_HUMAN
θ value	1.06045e-08 (rank : 50)	NC score	0.546427 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

PCOC1_HUMAN
θ value	1.38499e-08 (rank : 51)	NC score	0.624363 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	75
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

CFAB_MOUSE
θ value	2.36244e-08 (rank : 52)	NC score	0.400924 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	262	Shared Neighborhood Hits	69
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
θ value	4.0297e-08 (rank : 53)	NC score	0.398636 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO7_HUMAN
θ value	4.0297e-08 (rank : 54)	NC score	0.317231 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	62
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PCOC1_MOUSE
θ value	5.26297e-08 (rank : 55)	NC score	0.623891 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

SUSD4_MOUSE
θ value	5.26297e-08 (rank : 56)	NC score	0.571210 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	122	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

PCOC2_MOUSE
θ value	6.87365e-08 (rank : 57)	NC score	0.611021 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

CUZD1_MOUSE
θ value	1.17247e-07 (rank : 58)	NC score	0.533346 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	59
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

NRP1_HUMAN
θ value	1.53129e-07 (rank : 59)	NC score	0.498935 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DMBT1_MOUSE
θ value	2.61198e-07 (rank : 60)	NC score	0.457061 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	134	Shared Neighborhood Hits	64
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

FHR4_HUMAN
θ value	3.41135e-07 (rank : 61)	NC score	0.543477 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

KREM1_MOUSE
θ value	3.41135e-07 (rank : 62)	NC score	0.381405 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

FHR5_HUMAN
θ value	4.45536e-07 (rank : 63)	NC score	0.582602 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

MFRP_HUMAN
θ value	5.81887e-07 (rank : 64)	NC score	0.536742 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

SUSD4_HUMAN
θ value	5.81887e-07 (rank : 65)	NC score	0.570541 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LRP12_HUMAN
θ value	9.92553e-07 (rank : 66)	NC score	0.451347 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

KREM1_HUMAN
θ value	1.69304e-06 (rank : 67)	NC score	0.385085 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LRP12_MOUSE
θ value	1.69304e-06 (rank : 68)	NC score	0.452787 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

ENTK_MOUSE
θ value	2.21117e-06 (rank : 69)	NC score	0.239322 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ST14_HUMAN
θ value	3.77169e-06 (rank : 70)	NC score	0.247627 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	409	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TSG6_MOUSE
θ value	3.77169e-06 (rank : 71)	NC score	0.511348 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

C1RB_MOUSE
θ value	6.43352e-06 (rank : 72)	NC score	0.400720 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	380	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

DMBT1_HUMAN
θ value	6.43352e-06 (rank : 73)	NC score	0.389951 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

TSG6_HUMAN
θ value	1.43324e-05 (rank : 74)	NC score	0.511195 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

C1RA_MOUSE
θ value	2.44474e-05 (rank : 75)	NC score	0.404869 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	379	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

FHR2_HUMAN
θ value	2.44474e-05 (rank : 76)	NC score	0.505696 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

CN155_HUMAN
θ value	3.19293e-05 (rank : 77)	NC score	0.101657 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SRPX_HUMAN
θ value	3.19293e-05 (rank : 78)	NC score	0.520439 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

FHR1_HUMAN
θ value	4.1701e-05 (rank : 79)	NC score	0.533732 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

SCUB3_HUMAN
θ value	4.1701e-05 (rank : 80)	NC score	0.194540 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	428	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	5.44631e-05 (rank : 81)	NC score	0.194813 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	442	Shared Neighborhood Hits	77
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

C1R_HUMAN
θ value	7.1131e-05 (rank : 82)	NC score	0.401326 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	99
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

SRPX_MOUSE
θ value	7.1131e-05 (rank : 83)	NC score	0.527429 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

NFH_MOUSE
θ value	9.29e-05 (rank : 84)	NC score	0.039761 (rank : 424)
Query Neighborhood Hits	289	Target Neighborhood Hits	2247	Shared Neighborhood Hits	104
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ST14_MOUSE
θ value	9.29e-05 (rank : 85)	NC score	0.247869 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	9.29e-05 (rank : 86)	NC score	0.283577 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD2_HUMAN
θ value	9.29e-05 (rank : 87)	NC score	0.385738 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO6_HUMAN
θ value	0.00035302 (rank : 88)	NC score	0.290234 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

DCBD2_MOUSE
θ value	0.00035302 (rank : 89)	NC score	0.398274 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ENTK_HUMAN
θ value	0.000602161 (rank : 90)	NC score	0.215368 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SUSD2_MOUSE
θ value	0.000602161 (rank : 91)	NC score	0.379933 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

DCBD2_HUMAN
θ value	0.000786445 (rank : 92)	NC score	0.415000 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

PERT_MOUSE
θ value	0.00102713 (rank : 93)	NC score	0.210499 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	66
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_HUMAN
θ value	0.00134147 (rank : 94)	NC score	0.202597 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	65
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SON_HUMAN
θ value	0.00134147 (rank : 95)	NC score	0.076529 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	1568	Shared Neighborhood Hits	120
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CO2_HUMAN
θ value	0.00228821 (rank : 96)	NC score	0.386500 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	66
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

WASF1_HUMAN
θ value	0.00228821 (rank : 97)	NC score	0.072061 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

WASF1_MOUSE
θ value	0.00228821 (rank : 98)	NC score	0.072210 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

RGS3_MOUSE
θ value	0.00298849 (rank : 99)	NC score	0.062906 (rank : 334)
Query Neighborhood Hits	289	Target Neighborhood Hits	1621	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NETO2_HUMAN
θ value	0.00390308 (rank : 100)	NC score	0.506929 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

LRP3_HUMAN
θ value	0.00665767 (rank : 101)	NC score	0.369215 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	280	Shared Neighborhood Hits	82
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

NETO1_HUMAN
θ value	0.00665767 (rank : 102)	NC score	0.509043 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_MOUSE
θ value	0.00665767 (rank : 103)	NC score	0.504235 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

PAPPA_HUMAN
θ value	0.00665767 (rank : 104)	NC score	0.401238 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

RGS3_HUMAN
θ value	0.00869519 (rank : 105)	NC score	0.058597 (rank : 366)
Query Neighborhood Hits	289	Target Neighborhood Hits	1375	Shared Neighborhood Hits	118
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SUSD3_MOUSE
θ value	0.00869519 (rank : 106)	NC score	0.310422 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

PAPPA_MOUSE
θ value	0.0113563 (rank : 107)	NC score	0.399378 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SON_MOUSE
θ value	0.0113563 (rank : 108)	NC score	0.075288 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	957	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

LYAM1_HUMAN
θ value	0.0148317 (rank : 109)	NC score	0.384514 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	315	Shared Neighborhood Hits	64
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NETO1_MOUSE
θ value	0.0148317 (rank : 110)	NC score	0.507663 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

GP126_HUMAN
θ value	0.0193708 (rank : 111)	NC score	0.325406 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	187	Shared Neighborhood Hits	66
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

PCLO_MOUSE
θ value	0.0193708 (rank : 112)	NC score	0.052386 (rank : 394)
Query Neighborhood Hits	289	Target Neighborhood Hits	2275	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

K1802_MOUSE
θ value	0.0252991 (rank : 113)	NC score	0.051673 (rank : 400)
Query Neighborhood Hits	289	Target Neighborhood Hits	1596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LYAM1_MOUSE
θ value	0.0252991 (rank : 114)	NC score	0.386979 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	332	Shared Neighborhood Hits	69
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

AL2S4_MOUSE
θ value	0.0330416 (rank : 115)	NC score	0.057000 (rank : 375)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	28
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

CBP_HUMAN
θ value	0.0330416 (rank : 116)	NC score	0.061386 (rank : 346)
Query Neighborhood Hits	289	Target Neighborhood Hits	941	Shared Neighborhood Hits	90
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

KREM2_HUMAN
θ value	0.0330416 (rank : 117)	NC score	0.368308 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

SHAN1_HUMAN
θ value	0.0330416 (rank : 118)	NC score	0.023706 (rank : 461)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

KREM2_MOUSE
θ value	0.0563607 (rank : 119)	NC score	0.341060 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

MLL3_HUMAN
θ value	0.0563607 (rank : 120)	NC score	0.050497 (rank : 408)
Query Neighborhood Hits	289	Target Neighborhood Hits	1644	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CO2_MOUSE
θ value	0.0736092 (rank : 121)	NC score	0.338900 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	250	Shared Neighborhood Hits	66
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

GABR1_HUMAN
θ value	0.0736092 (rank : 122)	NC score	0.237703 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0.0736092 (rank : 123)	NC score	0.236691 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GNAS1_HUMAN
θ value	0.0961366 (rank : 124)	NC score	0.020126 (rank : 477)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

OGFR_HUMAN
θ value	0.0961366 (rank : 125)	NC score	0.057005 (rank : 374)
Query Neighborhood Hits	289	Target Neighborhood Hits	1582	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CBP_MOUSE
θ value	0.125558 (rank : 126)	NC score	0.060001 (rank : 358)
Query Neighborhood Hits	289	Target Neighborhood Hits	1051	Shared Neighborhood Hits	99
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DYN2_MOUSE
θ value	0.125558 (rank : 127)	NC score	0.019633 (rank : 479)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

PCLO_HUMAN
θ value	0.125558 (rank : 128)	NC score	0.052387 (rank : 393)
Query Neighborhood Hits	289	Target Neighborhood Hits	2046	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ROBO1_MOUSE
θ value	0.125558 (rank : 129)	NC score	0.012559 (rank : 505)
Query Neighborhood Hits	289	Target Neighborhood Hits	559	Shared Neighborhood Hits	16
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

CAC1B_HUMAN
θ value	0.163984 (rank : 130)	NC score	0.010761 (rank : 510)
Query Neighborhood Hits	289	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PDGFD_HUMAN
θ value	0.163984 (rank : 131)	NC score	0.473404 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

DCBD1_HUMAN
θ value	0.21417 (rank : 132)	NC score	0.357141 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

NFAC1_HUMAN
θ value	0.21417 (rank : 133)	NC score	0.030226 (rank : 443)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

ROBO1_HUMAN
θ value	0.21417 (rank : 134)	NC score	0.012230 (rank : 506)
Query Neighborhood Hits	289	Target Neighborhood Hits	529	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

CDN1C_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.057649 (rank : 370)
Query Neighborhood Hits	289	Target Neighborhood Hits	168	Shared Neighborhood Hits	25
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PRR12_HUMAN
θ value	0.279714 (rank : 136)	NC score	0.070110 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	460	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RFX1_HUMAN
θ value	0.365318 (rank : 137)	NC score	0.036001 (rank : 432)
Query Neighborhood Hits	289	Target Neighborhood Hits	256	Shared Neighborhood Hits	34
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SUSD3_HUMAN
θ value	0.365318 (rank : 138)	NC score	0.205014 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

WASIP_HUMAN
θ value	0.365318 (rank : 139)	NC score	0.060564 (rank : 356)
Query Neighborhood Hits	289	Target Neighborhood Hits	458	Shared Neighborhood Hits	44
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BRD4_HUMAN
θ value	0.47712 (rank : 140)	NC score	0.038595 (rank : 426)
Query Neighborhood Hits	289	Target Neighborhood Hits	851	Shared Neighborhood Hits	54
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MUC7_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.061779 (rank : 343)
Query Neighborhood Hits	289	Target Neighborhood Hits	538	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

GP112_HUMAN
θ value	0.62314 (rank : 142)	NC score	0.021477 (rank : 468)
Query Neighborhood Hits	289	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

LATS1_MOUSE
θ value	0.62314 (rank : 143)	NC score	-0.000429 (rank : 549)
Query Neighborhood Hits	289	Target Neighborhood Hits	1027	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

MAP1A_HUMAN
θ value	0.62314 (rank : 144)	NC score	0.028239 (rank : 448)
Query Neighborhood Hits	289	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MLL2_HUMAN
θ value	0.62314 (rank : 145)	NC score	0.044248 (rank : 414)
Query Neighborhood Hits	289	Target Neighborhood Hits	1788	Shared Neighborhood Hits	102
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SYNJ1_MOUSE
θ value	0.62314 (rank : 146)	NC score	0.035824 (rank : 433)
Query Neighborhood Hits	289	Target Neighborhood Hits	516	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

WASIP_MOUSE
θ value	0.62314 (rank : 147)	NC score	0.058132 (rank : 369)
Query Neighborhood Hits	289	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WHRN_MOUSE
θ value	0.62314 (rank : 148)	NC score	0.020281 (rank : 476)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

K1802_HUMAN
θ value	0.813845 (rank : 149)	NC score	0.039530 (rank : 425)
Query Neighborhood Hits	289	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NELFA_HUMAN
θ value	0.813845 (rank : 150)	NC score	0.041705 (rank : 422)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

NRX1A_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.032235 (rank : 439)
Query Neighborhood Hits	289	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	0.813845 (rank : 152)	NC score	0.032345 (rank : 438)
Query Neighborhood Hits	289	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ZYX_MOUSE
θ value	0.813845 (rank : 153)	NC score	0.020827 (rank : 473)
Query Neighborhood Hits	289	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

BRD4_MOUSE
θ value	1.06291 (rank : 154)	NC score	0.038421 (rank : 428)
Query Neighborhood Hits	289	Target Neighborhood Hits	845	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

MLL4_HUMAN
θ value	1.06291 (rank : 155)	NC score	0.042165 (rank : 420)
Query Neighborhood Hits	289	Target Neighborhood Hits	722	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRG4_MOUSE
θ value	1.06291 (rank : 156)	NC score	0.042142 (rank : 421)
Query Neighborhood Hits	289	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

YLPM1_HUMAN
θ value	1.06291 (rank : 157)	NC score	0.044740 (rank : 413)
Query Neighborhood Hits	289	Target Neighborhood Hits	670	Shared Neighborhood Hits	58
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ZBT7A_MOUSE
θ value	1.06291 (rank : 158)	NC score	-0.005481 (rank : 555)
Query Neighborhood Hits	289	Target Neighborhood Hits	795	Shared Neighborhood Hits	8
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).

ZN132_HUMAN
θ value	1.06291 (rank : 159)	NC score	-0.006664 (rank : 557)
Query Neighborhood Hits	289	Target Neighborhood Hits	752	Shared Neighborhood Hits	9
SwissProt Accessions	P52740	Gene names	ZNF132
Domain Architecture	No domain graphic available
Description	Zinc finger protein 132.

ABI3_HUMAN
θ value	1.38821 (rank : 160)	NC score	0.022941 (rank : 467)
Query Neighborhood Hits	289	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

COHA1_MOUSE
θ value	1.38821 (rank : 161)	NC score	0.023570 (rank : 463)
Query Neighborhood Hits	289	Target Neighborhood Hits	414	Shared Neighborhood Hits	39
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CRX_MOUSE
θ value	1.38821 (rank : 162)	NC score	0.002265 (rank : 541)
Query Neighborhood Hits	289	Target Neighborhood Hits	359	Shared Neighborhood Hits	9
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

CSKI2_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.012844 (rank : 503)
Query Neighborhood Hits	289	Target Neighborhood Hits	747	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GLI2_HUMAN
θ value	1.38821 (rank : 164)	NC score	-0.001932 (rank : 551)
Query Neighborhood Hits	289	Target Neighborhood Hits	971	Shared Neighborhood Hits	34
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NSD1_MOUSE
θ value	1.38821 (rank : 165)	NC score	0.028342 (rank : 446)
Query Neighborhood Hits	289	Target Neighborhood Hits	472	Shared Neighborhood Hits	37
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RREB1_HUMAN
θ value	1.38821 (rank : 166)	NC score	0.000901 (rank : 545)
Query Neighborhood Hits	289	Target Neighborhood Hits	879	Shared Neighborhood Hits	24
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SYN1_HUMAN
θ value	1.38821 (rank : 167)	NC score	0.036925 (rank : 431)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	46
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TITIN_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.005131 (rank : 531)
Query Neighborhood Hits	289	Target Neighborhood Hits	2923	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

3BP1_HUMAN
θ value	1.81305 (rank : 169)	NC score	0.024133 (rank : 457)
Query Neighborhood Hits	289	Target Neighborhood Hits	376	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ATX2L_HUMAN
θ value	1.81305 (rank : 170)	NC score	0.033307 (rank : 436)
Query Neighborhood Hits	289	Target Neighborhood Hits	443	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

BAT2_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.046562 (rank : 411)
Query Neighborhood Hits	289	Target Neighborhood Hits	931	Shared Neighborhood Hits	79
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CO1A1_MOUSE
θ value	1.81305 (rank : 172)	NC score	0.021447 (rank : 469)
Query Neighborhood Hits	289	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COIA1_HUMAN
θ value	1.81305 (rank : 173)	NC score	0.028069 (rank : 450)
Query Neighborhood Hits	289	Target Neighborhood Hits	447	Shared Neighborhood Hits	46
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GGA1_MOUSE
θ value	1.81305 (rank : 174)	NC score	0.016530 (rank : 488)
Query Neighborhood Hits	289	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

MINT_MOUSE
θ value	1.81305 (rank : 175)	NC score	0.033218 (rank : 437)
Query Neighborhood Hits	289	Target Neighborhood Hits	1514	Shared Neighborhood Hits	91
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOR2_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.029902 (rank : 444)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PDC6I_MOUSE
θ value	1.81305 (rank : 177)	NC score	0.027015 (rank : 454)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

CO1A1_HUMAN
θ value	2.36792 (rank : 178)	NC score	0.021346 (rank : 471)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	42
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COEA1_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.021393 (rank : 470)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	41
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COIA1_MOUSE
θ value	2.36792 (rank : 180)	NC score	0.027336 (rank : 453)
Query Neighborhood Hits	289	Target Neighborhood Hits	481	Shared Neighborhood Hits	52
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CTGE5_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.002262 (rank : 542)
Query Neighborhood Hits	289	Target Neighborhood Hits	800	Shared Neighborhood Hits	17
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DCBD1_MOUSE
θ value	2.36792 (rank : 182)	NC score	0.417956 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DNL1_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.020069 (rank : 478)
Query Neighborhood Hits	289	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

ENAH_MOUSE
θ value	2.36792 (rank : 184)	NC score	0.035463 (rank : 434)
Query Neighborhood Hits	289	Target Neighborhood Hits	919	Shared Neighborhood Hits	60
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

GORS2_MOUSE
θ value	2.36792 (rank : 185)	NC score	0.023081 (rank : 465)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

LRP10_MOUSE
θ value	2.36792 (rank : 186)	NC score	0.184163 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MLL3_MOUSE
θ value	2.36792 (rank : 187)	NC score	0.044122 (rank : 416)
Query Neighborhood Hits	289	Target Neighborhood Hits	1399	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NRCAM_MOUSE
θ value	2.36792 (rank : 188)	NC score	0.006038 (rank : 528)
Query Neighborhood Hits	289	Target Neighborhood Hits	432	Shared Neighborhood Hits	9
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PI5PA_HUMAN
θ value	2.36792 (rank : 189)	NC score	0.038510 (rank : 427)
Query Neighborhood Hits	289	Target Neighborhood Hits	749	Shared Neighborhood Hits	86
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RFX1_MOUSE
θ value	2.36792 (rank : 190)	NC score	0.026005 (rank : 455)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SAPS1_HUMAN
θ value	2.36792 (rank : 191)	NC score	0.037266 (rank : 430)
Query Neighborhood Hits	289	Target Neighborhood Hits	704	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SFPQ_MOUSE
θ value	2.36792 (rank : 192)	NC score	0.027920 (rank : 452)
Query Neighborhood Hits	289	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SGIP1_HUMAN
θ value	2.36792 (rank : 193)	NC score	0.043193 (rank : 418)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TNR25_HUMAN
θ value	2.36792 (rank : 194)	NC score	0.016601 (rank : 486)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TULP4_MOUSE
θ value	2.36792 (rank : 195)	NC score	0.017743 (rank : 482)
Query Neighborhood Hits	289	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ATRN_MOUSE
θ value	3.0926 (rank : 196)	NC score	0.228570 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	519	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BAT3_MOUSE
θ value	3.0926 (rank : 197)	NC score	0.041474 (rank : 423)
Query Neighborhood Hits	289	Target Neighborhood Hits	518	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

CIC_MOUSE
θ value	3.0926 (rank : 198)	NC score	0.028127 (rank : 449)
Query Neighborhood Hits	289	Target Neighborhood Hits	742	Shared Neighborhood Hits	69
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CT175_HUMAN
θ value	3.0926 (rank : 199)	NC score	0.021175 (rank : 472)
Query Neighborhood Hits	289	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MK2, Q5QPB6, Q9NQQ2	Gene names	C20orf175
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf175.

FRAS1_MOUSE
θ value	3.0926 (rank : 200)	NC score	0.020819 (rank : 474)
Query Neighborhood Hits	289	Target Neighborhood Hits	747	Shared Neighborhood Hits	31
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KCNH2_HUMAN
θ value	3.0926 (rank : 201)	NC score	0.006568 (rank : 523)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

NRX2A_HUMAN
θ value	3.0926 (rank : 202)	NC score	0.037973 (rank : 429)
Query Neighborhood Hits	289	Target Neighborhood Hits	614	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PAK4_MOUSE
θ value	3.0926 (rank : 203)	NC score	-0.004197 (rank : 553)
Query Neighborhood Hits	289	Target Neighborhood Hits	1098	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

SALL3_HUMAN
θ value	3.0926 (rank : 204)	NC score	0.000228 (rank : 547)
Query Neighborhood Hits	289	Target Neighborhood Hits	1066	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ABI3_MOUSE
θ value	4.03905 (rank : 205)	NC score	0.019251 (rank : 480)
Query Neighborhood Hits	289	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

CD248_HUMAN
θ value	4.03905 (rank : 206)	NC score	0.096837 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	679	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CNTP3_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.048360 (rank : 410)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

DAB2_MOUSE
θ value	4.03905 (rank : 208)	NC score	0.016389 (rank : 489)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

EMIL1_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.012142 (rank : 507)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

FMNL_MOUSE
θ value	4.03905 (rank : 210)	NC score	0.020454 (rank : 475)
Query Neighborhood Hits	289	Target Neighborhood Hits	428	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

IL12B_HUMAN
θ value	4.03905 (rank : 211)	NC score	0.013198 (rank : 501)
Query Neighborhood Hits	289	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

LRP10_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.160662 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MAGI2_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.012640 (rank : 504)
Query Neighborhood Hits	289	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

PO6F2_MOUSE
θ value	4.03905 (rank : 214)	NC score	0.011855 (rank : 508)
Query Neighborhood Hits	289	Target Neighborhood Hits	639	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RECQ4_MOUSE
θ value	4.03905 (rank : 215)	NC score	0.007277 (rank : 521)
Query Neighborhood Hits	289	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

TCOF_HUMAN
θ value	4.03905 (rank : 216)	NC score	0.028332 (rank : 447)
Query Neighborhood Hits	289	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TSK_HUMAN
θ value	4.03905 (rank : 217)	NC score	0.000012 (rank : 548)
Query Neighborhood Hits	289	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

ALEX_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.044136 (rank : 415)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	44
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

BAT2_MOUSE
θ value	5.27518 (rank : 219)	NC score	0.043779 (rank : 417)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BRD9_MOUSE
θ value	5.27518 (rank : 220)	NC score	0.014922 (rank : 494)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

COAA1_HUMAN
θ value	5.27518 (rank : 221)	NC score	0.017264 (rank : 484)
Query Neighborhood Hits	289	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CRTC1_MOUSE
θ value	5.27518 (rank : 222)	NC score	0.031876 (rank : 441)
Query Neighborhood Hits	289	Target Neighborhood Hits	230	Shared Neighborhood Hits	34
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

FOXJ2_HUMAN
θ value	5.27518 (rank : 223)	NC score	0.003922 (rank : 534)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

IASPP_HUMAN
θ value	5.27518 (rank : 224)	NC score	0.013723 (rank : 499)
Query Neighborhood Hits	289	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IRF5_MOUSE
θ value	5.27518 (rank : 225)	NC score	0.005939 (rank : 529)
Query Neighborhood Hits	289	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

LATS1_HUMAN
θ value	5.27518 (rank : 226)	NC score	-0.002265 (rank : 552)
Query Neighborhood Hits	289	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

NCA11_MOUSE
θ value	5.27518 (rank : 227)	NC score	0.014118 (rank : 496)
Query Neighborhood Hits	289	Target Neighborhood Hits	661	Shared Neighborhood Hits	39
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PAP2_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.324446 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PO121_HUMAN
θ value	5.27518 (rank : 229)	NC score	0.031985 (rank : 440)
Query Neighborhood Hits	289	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RTN2_MOUSE
θ value	5.27518 (rank : 230)	NC score	0.009098 (rank : 515)
Query Neighborhood Hits	289	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

SDK1_MOUSE
θ value	5.27518 (rank : 231)	NC score	0.006670 (rank : 522)
Query Neighborhood Hits	289	Target Neighborhood Hits	495	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SFR15_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.034254 (rank : 435)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SNX15_MOUSE
θ value	5.27518 (rank : 233)	NC score	0.009595 (rank : 512)
Query Neighborhood Hits	289	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

TCGAP_HUMAN
θ value	5.27518 (rank : 234)	NC score	0.024074 (rank : 458)
Query Neighborhood Hits	289	Target Neighborhood Hits	872	Shared Neighborhood Hits	80
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TM108_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.031542 (rank : 442)
Query Neighborhood Hits	289	Target Neighborhood Hits	336	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

WASF3_MOUSE
θ value	5.27518 (rank : 236)	NC score	0.044878 (rank : 412)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

WNK2_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.003708 (rank : 535)
Query Neighborhood Hits	289	Target Neighborhood Hits	1407	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AAK1_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.002859 (rank : 539)
Query Neighborhood Hits	289	Target Neighborhood Hits	1077	Shared Neighborhood Hits	56
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CONA1_MOUSE
θ value	6.88961 (rank : 239)	NC score	0.015384 (rank : 492)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

HXB2_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.000559 (rank : 546)
Query Neighborhood Hits	289	Target Neighborhood Hits	367	Shared Neighborhood Hits	13
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

IL3B2_MOUSE
θ value	6.88961 (rank : 241)	NC score	0.023747 (rank : 460)
Query Neighborhood Hits	289	Target Neighborhood Hits	372	Shared Neighborhood Hits	53
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IRS2_MOUSE
θ value	6.88961 (rank : 242)	NC score	0.017084 (rank : 485)
Query Neighborhood Hits	289	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

NXPH2_MOUSE
θ value	6.88961 (rank : 243)	NC score	0.006487 (rank : 524)
Query Neighborhood Hits	289	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61199, Q8BIN8	Gene names	Nxph2, Nph2
Domain Architecture	No domain graphic available
Description	Neurexophilin-2 precursor.

PDCD7_HUMAN
θ value	6.88961 (rank : 244)	NC score	0.023529 (rank : 464)
Query Neighborhood Hits	289	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

PTPRN_MOUSE
θ value	6.88961 (rank : 245)	NC score	0.003212 (rank : 538)
Query Neighborhood Hits	289	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RP1L1_HUMAN
θ value	6.88961 (rank : 246)	NC score	0.017584 (rank : 483)
Query Neighborhood Hits	289	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RTP4_HUMAN
θ value	6.88961 (rank : 247)	NC score	0.008639 (rank : 516)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DX8, Q9H4F3	Gene names	RTP4, IFRG28
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 4 (28 kDa interferon-responsive protein).

S29A3_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.007605 (rank : 519)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZD2, Q7RTT8, Q8IVZ0	Gene names	SLC29A3, ENT3
Domain Architecture
Description	Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3).

SDK1_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.006130 (rank : 527)
Query Neighborhood Hits	289	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SF3B4_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.009363 (rank : 513)
Query Neighborhood Hits	289	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

ASPP2_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.007368 (rank : 520)
Query Neighborhood Hits	289	Target Neighborhood Hits	1156	Shared Neighborhood Hits	46
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ATS20_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.002425 (rank : 540)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

BRD8_MOUSE
θ value	8.99809 (rank : 253)	NC score	0.023048 (rank : 466)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CA106_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.014657 (rank : 495)
Query Neighborhood Hits	289	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CEND3_MOUSE
θ value	8.99809 (rank : 255)	NC score	0.003654 (rank : 536)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CO4A4_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.015911 (rank : 490)
Query Neighborhood Hits	289	Target Neighborhood Hits	440	Shared Neighborhood Hits	35
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CXA8_MOUSE
θ value	8.99809 (rank : 257)	NC score	0.001114 (rank : 544)
Query Neighborhood Hits	289	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P28236	Gene names	Gja8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

DDFL1_HUMAN
θ value	8.99809 (rank : 258)	NC score	0.004302 (rank : 532)
Query Neighborhood Hits	289	Target Neighborhood Hits	353	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

EMR1_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.065317 (rank : 323)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	43
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ENPP2_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.006426 (rank : 525)
Query Neighborhood Hits	289	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

ERCC6_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.002110 (rank : 543)
Query Neighborhood Hits	289	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

GGA1_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.013993 (rank : 497)
Query Neighborhood Hits	289	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GRIPE_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.005270 (rank : 530)
Query Neighborhood Hits	289	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

HDAC6_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.003405 (rank : 537)
Query Neighborhood Hits	289	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HGS_MOUSE
θ value	8.99809 (rank : 265)	NC score	0.013765 (rank : 498)
Query Neighborhood Hits	289	Target Neighborhood Hits	589	Shared Neighborhood Hits	41
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HME1_MOUSE
θ value	8.99809 (rank : 266)	NC score	-0.001167 (rank : 550)
Query Neighborhood Hits	289	Target Neighborhood Hits	397	Shared Neighborhood Hits	16
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

IL4RA_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.013486 (rank : 500)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

JIP2_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.018182 (rank : 481)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

M3K11_HUMAN
θ value	8.99809 (rank : 269)	NC score	-0.004851 (rank : 554)
Query Neighborhood Hits	289	Target Neighborhood Hits	1136	Shared Neighborhood Hits	35
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

MKL2_HUMAN
θ value	8.99809 (rank : 270)	NC score	0.012874 (rank : 502)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MRCKB_MOUSE
θ value	8.99809 (rank : 271)	NC score	-0.008349 (rank : 559)
Query Neighborhood Hits	289	Target Neighborhood Hits	2180	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NCOR1_MOUSE
θ value	8.99809 (rank : 272)	NC score	0.016591 (rank : 487)
Query Neighborhood Hits	289	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NEUL1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.008245 (rank : 518)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	8.99809 (rank : 274)	NC score	0.008301 (rank : 517)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NSD1_HUMAN
θ value	8.99809 (rank : 275)	NC score	0.023638 (rank : 462)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PAK6_HUMAN
θ value	8.99809 (rank : 276)	NC score	-0.006196 (rank : 556)
Query Neighborhood Hits	289	Target Neighborhood Hits	915	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PAPOA_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.011350 (rank : 509)
Query Neighborhood Hits	289	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

PDC6I_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.023978 (rank : 459)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

PDXL2_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.010368 (rank : 511)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PELP1_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.024622 (rank : 456)
Query Neighborhood Hits	289	Target Neighborhood Hits	596	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PSD4_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.015867 (rank : 491)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

RERE_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.028052 (rank : 451)
Query Neighborhood Hits	289	Target Neighborhood Hits	779	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.029876 (rank : 445)
Query Neighborhood Hits	289	Target Neighborhood Hits	785	Shared Neighborhood Hits	52
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RET_MOUSE
θ value	8.99809 (rank : 284)	NC score	-0.007610 (rank : 558)
Query Neighborhood Hits	289	Target Neighborhood Hits	884	Shared Neighborhood Hits	12
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIMB1_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.009333 (rank : 514)
Query Neighborhood Hits	289	Target Neighborhood Hits	1479	Shared Neighborhood Hits	66
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SL9A3_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.003968 (rank : 533)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

SRRM1_MOUSE
θ value	8.99809 (rank : 287)	NC score	0.042445 (rank : 419)
Query Neighborhood Hits	289	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

STAU2_MOUSE
θ value	8.99809 (rank : 288)	NC score	0.006184 (rank : 526)
Query Neighborhood Hits	289	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

WBS14_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.015279 (rank : 493)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ACRO_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.080921 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	291	Shared Neighborhood Hits	34
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.079599 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.078430 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	25
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ASTL_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.169410 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	38
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.164190 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATRN_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.230055 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	525	Shared Neighborhood Hits	66
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BSSP4_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.078708 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.081132 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1QR1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.077276 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	493	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.095620 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CATG_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.065500 (rank : 321)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.067079 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CD248_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.099140 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	578	Shared Neighborhood Hits	76
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.065408 (rank : 322)
Query Neighborhood Hits	289	Target Neighborhood Hits	353	Shared Neighborhood Hits	35
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CDCP1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.051152 (rank : 405)
Query Neighborhood Hits	289	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

CFAD_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.067436 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.069159 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAI_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.095625 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.096159 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	34
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLC14_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.052024 (rank : 396)
Query Neighborhood Hits	289	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.050639 (rank : 406)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLCR_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.077812 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO9_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.057102 (rank : 373)
Query Neighborhood Hits	289	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.059288 (rank : 364)
Query Neighborhood Hits	289	Target Neighborhood Hits	153	Shared Neighborhood Hits	21
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.091888 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	453	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.089030 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CSPG2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.093298 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	681	Shared Neighborhood Hits	74
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.095409 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	711	Shared Neighborhood Hits	74
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.100019 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	676	Shared Neighborhood Hits	91
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.106795 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	657	Shared Neighborhood Hits	82
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTRB1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.075622 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.076689 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

DESC4_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.081253 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

EDIL3_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.082755 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.081037 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFB2_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.062606 (rank : 337)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

EGFL7_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.081513 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.054416 (rank : 382)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.077782 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	270	Shared Neighborhood Hits	27
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.084094 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	266	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGF_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.062190 (rank : 340)
Query Neighborhood Hits	289	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.069383 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA1_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.064444 (rank : 329)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.072299 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.072897 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.070445 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.061928 (rank : 342)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.060861 (rank : 353)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

EMR1_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.057616 (rank : 372)
Query Neighborhood Hits	289	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.064923 (rank : 326)
Query Neighborhood Hits	289	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FA10_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.112329 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.109642 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	435	Shared Neighborhood Hits	44
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.081289 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.079805 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.087495 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	40
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA5_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.063835 (rank : 332)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.101117 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	404	Shared Neighborhood Hits	41
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.095238 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA8_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.061183 (rank : 348)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.060786 (rank : 354)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA9_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.104786 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	421	Shared Neighborhood Hits	44
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.080802 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.076344 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.081736 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.086375 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	505	Shared Neighborhood Hits	72
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.078820 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.080216 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.077337 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	31
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.076390 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.091545 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.097552 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	317	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.080021 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	557	Shared Neighborhood Hits	46
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.079228 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.080261 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.081314 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	549	Shared Neighborhood Hits	51
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.078359 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.077408 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	36
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.071044 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	343	Shared Neighborhood Hits	36
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRAC_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.060349 (rank : 357)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

GRAD_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.061261 (rank : 347)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAE_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.059582 (rank : 360)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAF_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.059416 (rank : 363)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.059459 (rank : 362)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAH_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.070092 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.060935 (rank : 351)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.066205 (rank : 316)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

HABP2_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.088195 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	431	Shared Neighborhood Hits	39
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.084143 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.081035 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.081543 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.079840 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	37
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.082685 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.060751 (rank : 355)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.060951 (rank : 350)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGF_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.053852 (rank : 385)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.053769 (rank : 386)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.059917 (rank : 359)
Query Neighborhood Hits	289	Target Neighborhood Hits	983	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPTR_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.119292 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	19
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.148748 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	184	Shared Neighborhood Hits	36
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.123765 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	23
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IL2RA_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.089057 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

K0247_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.174769 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

K1B11_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.064975 (rank : 325)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B16_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.056948 (rank : 376)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

K1B21_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.063161 (rank : 333)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.065917 (rank : 319)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.064566 (rank : 328)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.061946 (rank : 341)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.064348 (rank : 330)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.068349 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.066480 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB4_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.061684 (rank : 344)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

K1KB5_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.065877 (rank : 320)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.062615 (rank : 336)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.070317 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.070674 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.068125 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.065930 (rank : 318)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.069016 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.070866 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.071736 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.066801 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.061591 (rank : 345)
Query Neighborhood Hits	289	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KLK1_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.067577 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.065169 (rank : 324)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK3_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.062388 (rank : 339)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

KLK4_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.066926 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.066839 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.072824 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.069546 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.070930 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.064778 (rank : 327)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.078981 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.080093 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

LDLR_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.084103 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.078780 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	45
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.076288 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	602	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.075878 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	606	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.070014 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	617	Shared Neighborhood Hits	59
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.095565 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	573	Shared Neighborhood Hits	56
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.078068 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.078546 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.054032 (rank : 384)
Query Neighborhood Hits	289	Target Neighborhood Hits	224	Shared Neighborhood Hits	35
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP6_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.062481 (rank : 338)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.062774 (rank : 335)
Query Neighborhood Hits	289	Target Neighborhood Hits	232	Shared Neighborhood Hits	39
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.076651 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	346	Shared Neighborhood Hits	43
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.081611 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.074738 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.072961 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	514	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.072467 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.071538 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.086001 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	552	Shared Neighborhood Hits	62
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.081875 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.079455 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.090047 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	53
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.072744 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	607	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MAMC2_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.051534 (rank : 401)
Query Neighborhood Hits	289	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MATN1_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.058544 (rank : 367)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	29
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.054238 (rank : 383)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.086427 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	365	Shared Neighborhood Hits	36
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.088446 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	356	Shared Neighborhood Hits	36
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.059514 (rank : 361)
Query Neighborhood Hits	289	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.058334 (rank : 368)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.081528 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	35
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.075469 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	277	Shared Neighborhood Hits	35
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCPT1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.053061 (rank : 389)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

MCPT1_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.057643 (rank : 371)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.058721 (rank : 365)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.054665 (rank : 379)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT5_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.050628 (rank : 407)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

MCPT6_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.074470 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MCPT8_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.052398 (rank : 392)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

MCPT9_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.051898 (rank : 399)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

MCPTX_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.051940 (rank : 397)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

MEGF6_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.083266 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEP1A_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.138275 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.134851 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.145573 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.153951 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MFGM_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.085813 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.071774 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NACAM_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.051511 (rank : 402)
Query Neighborhood Hits	289	Target Neighborhood Hits	1866	Shared Neighborhood Hits	126
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NELL2_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.056638 (rank : 377)
Query Neighborhood Hits	289	Target Neighborhood Hits	449	Shared Neighborhood Hits	39
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.054809 (rank : 378)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	39
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETR_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.088483 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.088188 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NID2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.054630 (rank : 380)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	35
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.051173 (rank : 404)
Query Neighborhood Hits	289	Target Neighborhood Hits	906	Shared Neighborhood Hits	57
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.052436 (rank : 391)
Query Neighborhood Hits	289	Target Neighborhood Hits	916	Shared Neighborhood Hits	70
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.053688 (rank : 387)
Query Neighborhood Hits	289	Target Neighborhood Hits	1113	Shared Neighborhood Hits	109
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.054527 (rank : 381)
Query Neighborhood Hits	289	Target Neighborhood Hits	1069	Shared Neighborhood Hits	96
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.050435 (rank : 409)
Query Neighborhood Hits	289	Target Neighborhood Hits	1062	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.051907 (rank : 398)
Query Neighborhood Hits	289	Target Neighborhood Hits	975	Shared Neighborhood Hits	72
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NRPN_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.071436 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.070170 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

PDGFD_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.456471 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGCA_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.095516 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	821	Shared Neighborhood Hits	85
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.088692 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	643	Shared Neighborhood Hits	67
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.087196 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	478	Shared Neighborhood Hits	65
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.072262 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PHXR5_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.067025 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.079198 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.081227 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.074306 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.075408 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.110604 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.111335 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.091395 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.084754 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.115679 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	42
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.116213 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	410	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.079924 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.078057 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.080085 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.078948 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

STAB1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.051506 (rank : 403)
Query Neighborhood Hits	289	Target Neighborhood Hits	546	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.052995 (rank : 390)
Query Neighborhood Hits	289	Target Neighborhood Hits	566	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TEST_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.078350 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.082445 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

THRB_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.095239 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	196	Shared Neighborhood Hits	22
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.094196 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TM11D_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.083539 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.082794 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.081126 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.081698 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.085845 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	31
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.085392 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	243	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.080149 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	28
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.079480 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.081175 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	203	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.081983 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.075885 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.075215 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS6_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.120242 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.119156 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.131226 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.127708 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.082699 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	276	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.082101 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	296	Shared Neighborhood Hits	34
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.081542 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.082239 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	334	Shared Neighborhood Hits	34
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.083846 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.090199 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.086887 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.061139 (rank : 349)
Query Neighborhood Hits	289	Target Neighborhood Hits	339	Shared Neighborhood Hits	33
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.060933 (rank : 352)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	32
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRY1_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.071559 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.073711 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.071988 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.071423 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.072150 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.073931 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.075626 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.073931 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.070982 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.080924 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.079001 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSP50_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.068987 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.076253 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	272	Shared Neighborhood Hits	24
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 549)	NC score	0.077829 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.052156 (rank : 395)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.066163 (rank : 317)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.064035 (rank : 331)
Query Neighborhood Hits	289	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.067857 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.070547 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	45
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.069149 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	360	Shared Neighborhood Hits	45
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

XLRS1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.071120 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.069634 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

ZAN_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.053390 (rank : 388)
Query Neighborhood Hits	289	Target Neighborhood Hits	679	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.076918 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

SEZ6L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	289
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD3_HUMAN
NC score	0.900445 (rank : 2)	θ value	3.14151e-61 (rank : 5)
Query Neighborhood Hits	289	Target Neighborhood Hits	199	Shared Neighborhood Hits	118
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
NC score	0.899998 (rank : 3)	θ value	2.03155e-68 (rank : 4)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	117
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
NC score	0.898829 (rank : 4)	θ value	2.3998e-69 (rank : 2)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	119
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
NC score	0.897567 (rank : 5)	θ value	4.09345e-69 (rank : 3)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	119
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

C4BB_HUMAN
NC score	0.718077 (rank : 6)	θ value	4.02038e-16 (rank : 17)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CR2_MOUSE
NC score	0.704833 (rank : 7)	θ value	4.9032e-22 (rank : 8)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR2_HUMAN
NC score	0.699298 (rank : 8)	θ value	1.058e-16 (rank : 15)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

C4BP_MOUSE
NC score	0.696881 (rank : 9)	θ value	9.90251e-15 (rank : 24)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CR1_HUMAN
NC score	0.693852 (rank : 10)	θ value	5.99374e-20 (rank : 11)
Query Neighborhood Hits	289	Target Neighborhood Hits	108	Shared Neighborhood Hits	68
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

C4BP_HUMAN
NC score	0.691474 (rank : 11)	θ value	1.16975e-15 (rank : 20)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	67
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

ZP3R_MOUSE
NC score	0.685870 (rank : 12)	θ value	9.90251e-15 (rank : 25)
Query Neighborhood Hits	289	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

DAF_HUMAN
NC score	0.678097 (rank : 13)	θ value	1.38178e-16 (rank : 16)
Query Neighborhood Hits	289	Target Neighborhood Hits	97	Shared Neighborhood Hits	67
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CRRY_MOUSE
NC score	0.677431 (rank : 14)	θ value	2.69671e-12 (rank : 37)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

MCP_HUMAN
NC score	0.673611 (rank : 15)	θ value	5.43371e-13 (rank : 35)
Query Neighborhood Hits	289	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MCP_MOUSE
NC score	0.663694 (rank : 16)	θ value	1.25267e-09 (rank : 44)
Query Neighborhood Hits	289	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

APOH_HUMAN
NC score	0.660749 (rank : 17)	θ value	2.13673e-09 (rank : 45)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

APOH_MOUSE
NC score	0.652170 (rank : 18)	θ value	2.13673e-09 (rank : 46)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

DAF2_MOUSE
NC score	0.649964 (rank : 19)	θ value	4.59992e-12 (rank : 40)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.648158 (rank : 20)	θ value	5.43371e-13 (rank : 34)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	92
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

F13B_MOUSE
NC score	0.639402 (rank : 21)	θ value	8.95645e-16 (rank : 19)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

CFAH_HUMAN
NC score	0.636510 (rank : 22)	θ value	2.20605e-14 (rank : 26)
Query Neighborhood Hits	289	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
NC score	0.635581 (rank : 23)	θ value	5.08577e-11 (rank : 43)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	67
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

F13B_HUMAN
NC score	0.625782 (rank : 24)	θ value	2.20605e-14 (rank : 27)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

PCOC1_HUMAN
NC score	0.624363 (rank : 25)	θ value	1.38499e-08 (rank : 51)
Query Neighborhood Hits	289	Target Neighborhood Hits	146	Shared Neighborhood Hits	75
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.623891 (rank : 26)	θ value	5.26297e-08 (rank : 55)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

TLL2_MOUSE
NC score	0.616766 (rank : 27)	θ value	2.59989e-23 (rank : 6)
Query Neighborhood Hits	289	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PCOC2_HUMAN
NC score	0.615881 (rank : 28)	θ value	8.11959e-09 (rank : 49)
Query Neighborhood Hits	289	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL2_HUMAN
NC score	0.613417 (rank : 29)	θ value	1.29031e-22 (rank : 7)
Query Neighborhood Hits	289	Target Neighborhood Hits	241	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.611791 (rank : 30)	θ value	8.36355e-22 (rank : 9)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	73
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

PCOC2_MOUSE
NC score	0.611021 (rank : 31)	θ value	6.87365e-08 (rank : 57)
Query Neighborhood Hits	289	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL1_MOUSE
NC score	0.610840 (rank : 32)	θ value	2.69047e-20 (rank : 10)
Query Neighborhood Hits	289	Target Neighborhood Hits	237	Shared Neighborhood Hits	74
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
NC score	0.608267 (rank : 33)	θ value	7.82807e-20 (rank : 13)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	73
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
NC score	0.607626 (rank : 34)	θ value	6.62687e-19 (rank : 14)
Query Neighborhood Hits	289	Target Neighborhood Hits	236	Shared Neighborhood Hits	73
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LYAM3_MOUSE
NC score	0.583015 (rank : 35)	θ value	5.25075e-16 (rank : 18)
Query Neighborhood Hits	289	Target Neighborhood Hits	390	Shared Neighborhood Hits	84
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

FHR5_HUMAN
NC score	0.582602 (rank : 36)	θ value	4.45536e-07 (rank : 63)
Query Neighborhood Hits	289	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

LYAM3_HUMAN
NC score	0.575886 (rank : 37)	θ value	4.16044e-13 (rank : 33)
Query Neighborhood Hits	289	Target Neighborhood Hits	378	Shared Neighborhood Hits	83
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SUSD4_MOUSE
NC score	0.571210 (rank : 38)	θ value	5.26297e-08 (rank : 56)
Query Neighborhood Hits	289	Target Neighborhood Hits	122	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_HUMAN
NC score	0.570541 (rank : 39)	θ value	5.81887e-07 (rank : 65)
Query Neighborhood Hits	289	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LYAM2_HUMAN
NC score	0.555087 (rank : 40)	θ value	1.58096e-12 (rank : 36)
Query Neighborhood Hits	289	Target Neighborhood Hits	394	Shared Neighborhood Hits	82
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MFRP_MOUSE
NC score	0.554606 (rank : 41)	θ value	6.00763e-12 (rank : 42)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

LYAM2_MOUSE
NC score	0.553050 (rank : 42)	θ value	3.52202e-12 (rank : 38)
Query Neighborhood Hits	289	Target Neighborhood Hits	420	Shared Neighborhood Hits	85
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CUZD1_HUMAN
NC score	0.546427 (rank : 43)	θ value	1.06045e-08 (rank : 50)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

FHR3_HUMAN
NC score	0.545773 (rank : 44)	θ value	2.79066e-09 (rank : 48)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
NC score	0.543477 (rank : 45)	θ value	3.41135e-07 (rank : 61)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

MFRP_HUMAN
NC score	0.536742 (rank : 46)	θ value	5.81887e-07 (rank : 64)
Query Neighborhood Hits	289	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

FHR1_HUMAN
NC score	0.533732 (rank : 47)	θ value	4.1701e-05 (rank : 79)
Query Neighborhood Hits	289	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

CUZD1_MOUSE
NC score	0.533346 (rank : 48)	θ value	1.17247e-07 (rank : 58)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	59
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

NRP2_MOUSE
NC score	0.528066 (rank : 49)	θ value	4.91457e-14 (rank : 28)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

SRPX_MOUSE
NC score	0.527429 (rank : 50)	θ value	7.1131e-05 (rank : 83)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

NRP2_HUMAN
NC score	0.525433 (rank : 51)	θ value	8.38298e-14 (rank : 31)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

SRPX_HUMAN
NC score	0.520439 (rank : 52)	θ value	3.19293e-05 (rank : 78)
Query Neighborhood Hits	289	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

TSG6_MOUSE
NC score	0.511348 (rank : 53)	θ value	3.77169e-06 (rank : 71)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.511195 (rank : 54)	θ value	1.43324e-05 (rank : 74)
Query Neighborhood Hits	289	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NETO1_HUMAN
NC score	0.509043 (rank : 55)	θ value	0.00665767 (rank : 102)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	67
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.507663 (rank : 56)	θ value	0.0148317 (rank : 110)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
NC score	0.506929 (rank : 57)	θ value	0.00390308 (rank : 100)
Query Neighborhood Hits	289	Target Neighborhood Hits	109	Shared Neighborhood Hits	66
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

FHR2_HUMAN
NC score	0.505696 (rank : 58)	θ value	2.44474e-05 (rank : 76)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

NETO2_MOUSE
NC score	0.504235 (rank : 59)	θ value	0.00665767 (rank : 103)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_MOUSE
NC score	0.503594 (rank : 60)	θ value	2.13673e-09 (rank : 47)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.498935 (rank : 61)	θ value	1.53129e-07 (rank : 59)
Query Neighborhood Hits	289	Target Neighborhood Hits	119	Shared Neighborhood Hits	64
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

PDGFD_HUMAN
NC score	0.473404 (rank : 62)	θ value	0.163984 (rank : 131)
Query Neighborhood Hits	289	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

DMBT1_MOUSE
NC score	0.457061 (rank : 63)	θ value	2.61198e-07 (rank : 60)
Query Neighborhood Hits	289	Target Neighborhood Hits	134	Shared Neighborhood Hits	64
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

PDGFD_MOUSE
NC score	0.456471 (rank : 64)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	289	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

LRP12_MOUSE
NC score	0.452787 (rank : 65)	θ value	1.69304e-06 (rank : 68)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.451347 (rank : 66)	θ value	9.92553e-07 (rank : 66)
Query Neighborhood Hits	289	Target Neighborhood Hits	205	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MASP2_MOUSE
NC score	0.432070 (rank : 67)	θ value	1.99529e-15 (rank : 22)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	109
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CUBN_HUMAN
NC score	0.428236 (rank : 68)	θ value	4.59992e-12 (rank : 39)
Query Neighborhood Hits	289	Target Neighborhood Hits	482	Shared Neighborhood Hits	85
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

C1S_HUMAN
NC score	0.425447 (rank : 69)	θ value	6.00763e-12 (rank : 41)
Query Neighborhood Hits	289	Target Neighborhood Hits	359	Shared Neighborhood Hits	104
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_HUMAN
NC score	0.422197 (rank : 70)	θ value	6.41864e-14 (rank : 29)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	106
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CUBN_MOUSE
NC score	0.419622 (rank : 71)	θ value	4.44505e-15 (rank : 23)
Query Neighborhood Hits	289	Target Neighborhood Hits	477	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DCBD1_MOUSE
NC score	0.417956 (rank : 72)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

MASP1_HUMAN
NC score	0.417343 (rank : 73)	θ value	5.99374e-20 (rank : 12)
Query Neighborhood Hits	289	Target Neighborhood Hits	369	Shared Neighborhood Hits	108
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

DCBD2_HUMAN
NC score	0.415000 (rank : 74)	θ value	0.000786445 (rank : 92)
Query Neighborhood Hits	289	Target Neighborhood Hits	118	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

CS1A_MOUSE
NC score	0.411129 (rank : 75)	θ value	8.38298e-14 (rank : 30)
Query Neighborhood Hits	289	Target Neighborhood Hits	360	Shared Neighborhood Hits	104
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.409417 (rank : 76)	θ value	4.16044e-13 (rank : 32)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP1_MOUSE
NC score	0.405972 (rank : 77)	θ value	1.52774e-15 (rank : 21)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	104
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

C1RA_MOUSE
NC score	0.404869 (rank : 78)	θ value	2.44474e-05 (rank : 75)
Query Neighborhood Hits	289	Target Neighborhood Hits	379	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1R_HUMAN
NC score	0.401326 (rank : 79)	θ value	7.1131e-05 (rank : 82)
Query Neighborhood Hits	289	Target Neighborhood Hits	364	Shared Neighborhood Hits	99
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

PAPPA_HUMAN
NC score	0.401238 (rank : 80)	θ value	0.00665767 (rank : 104)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	58
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CFAB_MOUSE
NC score	0.400924 (rank : 81)	θ value	2.36244e-08 (rank : 52)
Query Neighborhood Hits	289	Target Neighborhood Hits	262	Shared Neighborhood Hits	69
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

C1RB_MOUSE
NC score	0.400720 (rank : 82)	θ value	6.43352e-06 (rank : 72)
Query Neighborhood Hits	289	Target Neighborhood Hits	380	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

PAPPA_MOUSE
NC score	0.399378 (rank : 83)	θ value	0.0113563 (rank : 107)
Query Neighborhood Hits	289	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CFAB_HUMAN
NC score	0.398636 (rank : 84)	θ value	4.0297e-08 (rank : 53)
Query Neighborhood Hits	289	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

DCBD2_MOUSE
NC score	0.398274 (rank : 85)	θ value	0.00035302 (rank : 89)
Query Neighborhood Hits	289	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
NC score	0.389951 (rank : 86)	θ value	6.43352e-06 (rank : 73)
Query Neighborhood Hits	289	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

LYAM1_MOUSE
NC score	0.386979 (rank : 87)	θ value	0.0252991 (rank : 114)
Query Neighborhood Hits	289	Target Neighborhood Hits	332	Shared Neighborhood Hits	69
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CO2_HUMAN
NC score	0.386500 (rank : 88)	θ value	0.00228821 (rank : 96)
Query Neighborhood Hits	289	Target Neighborhood Hits	258	Shared Neighborhood Hits	66
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_HUMAN
NC score	0.385738 (rank : 89)	θ value	9.29e-05 (rank : 87)
Query Neighborhood Hits	289	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

KREM1_HUMAN
NC score	0.385085 (rank : 90)	θ value	1.69304e-06 (rank : 67)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LYAM1_HUMAN
NC score	0.384514 (rank : 91)	θ value	0.0148317 (rank : 109)
Query Neighborhood Hits	289	Target Neighborhood Hits	315	Shared Neighborhood Hits	64
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

KREM1_MOUSE
NC score	0.381405 (rank : 92)	θ value	3.41135e-07 (rank : 62)
Query Neighborhood Hits	289	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

SUSD2_MOUSE
NC score	0.379933 (rank : 93)	θ value	0.000602161 (rank : 91)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	63
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

LRP3_HUMAN
NC score	0.369215 (rank : 94)	θ value	0.00665767 (rank : 101)
Query Neighborhood Hits	289	Target Neighborhood Hits	280	Shared Neighborhood Hits	82
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

KREM2_HUMAN
NC score	0.368308 (rank : 95)	θ value	0.0330416 (rank : 117)
Query Neighborhood Hits	289	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

DCBD1_HUMAN
NC score	0.357141 (rank : 96)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	289	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

KREM2_MOUSE
NC score	0.341060 (rank : 97)	θ value	0.0563607 (rank : 119)
Query Neighborhood Hits	289	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

CO2_MOUSE
NC score	0.338900 (rank : 98)	θ value	0.0736092 (rank : 121)
Query Neighborhood Hits	289	Target Neighborhood Hits	250	Shared Neighborhood Hits	66
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

GP126_HUMAN
NC score	0.325406 (rank : 99)	θ value	0.0193708 (rank : 111)
Query Neighborhood Hits	289	Target Neighborhood Hits	187	Shared Neighborhood Hits	66
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

PAP2_HUMAN
NC score	0.324446 (rank : 100)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

CO7_HUMAN
NC score	0.317231 (rank : 101)	θ value	4.0297e-08 (rank : 54)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	62
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SUSD3_MOUSE
NC score	0.310422 (rank : 102)	θ value	0.00869519 (rank : 106)
Query Neighborhood Hits	289	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

CO6_HUMAN
NC score	0.290234 (rank : 103)	θ value	0.00035302 (rank : 88)
Query Neighborhood Hits	289	Target Neighborhood Hits	331	Shared Neighborhood Hits	77
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD1_HUMAN
NC score	0.283577 (rank : 104)	θ value	9.29e-05 (rank : 86)
Query Neighborhood Hits	289	Target Neighborhood Hits	285	Shared Neighborhood Hits	67
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

ST14_MOUSE
NC score	0.247869 (rank : 105)	θ value	9.29e-05 (rank : 85)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.247627 (rank : 106)	θ value	3.77169e-06 (rank : 70)
Query Neighborhood Hits	289	Target Neighborhood Hits	409	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ENTK_MOUSE
NC score	0.239322 (rank : 107)	θ value	2.21117e-06 (rank : 69)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GABR1_HUMAN
NC score	0.237703 (rank : 108)	θ value	0.0736092 (rank : 122)
Query Neighborhood Hits	289	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.236691 (rank : 109)	θ value	0.0736092 (rank : 123)
Query Neighborhood Hits	289	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

ATRN_HUMAN
NC score	0.230055 (rank : 110)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	289	Target Neighborhood Hits	525	Shared Neighborhood Hits	66
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.228570 (rank : 111)	θ value	3.0926 (rank : 196)
Query Neighborhood Hits	289	Target Neighborhood Hits	519	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ENTK_HUMAN
NC score	0.215368 (rank : 112)	θ value	0.000602161 (rank : 90)
Query Neighborhood Hits	289	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PERT_MOUSE
NC score	0.210499 (rank : 113)	θ value	0.00102713 (rank : 93)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	66
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SUSD3_HUMAN
NC score	0.205014 (rank : 114)	θ value	0.365318 (rank : 138)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

PERT_HUMAN
NC score	0.202597 (rank : 115)	θ value	0.00134147 (rank : 94)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	65
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SCUB3_MOUSE
NC score	0.194813 (rank : 116)	θ value	5.44631e-05 (rank : 81)
Query Neighborhood Hits	289	Target Neighborhood Hits	442	Shared Neighborhood Hits	77
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.194540 (rank : 117)	θ value	4.1701e-05 (rank : 80)
Query Neighborhood Hits	289	Target Neighborhood Hits	428	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LRP10_MOUSE
NC score	0.184163 (rank : 118)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	289	Target Neighborhood Hits	169	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

K0247_HUMAN
NC score	0.174769 (rank : 119)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	289	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

ASTL_HUMAN
NC score	0.169410 (rank : 120)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	38
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
NC score	0.164190 (rank : 121)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	289	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

LRP10_HUMAN
NC score	0.160662 (rank : 122)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MEP1B_MOUSE
NC score	0.153951 (rank : 123)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	289	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

HPT_HUMAN
NC score	0.148748 (rank : 124)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	289	Target Neighborhood Hits	184	Shared Neighborhood Hits	36
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

MEP1B_HUMAN
NC score	0.145573 (rank : 125)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	289	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1A_HUMAN
NC score	0.138275 (rank : 126)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	289	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
NC score	0.134851 (rank : 127)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

TMPS7_HUMAN
NC score	0.131226 (rank : 128)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	58
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
NC score	0.127708 (rank : 129)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

HPT_MOUSE
NC score	0.123765 (rank : 130)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	23
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

TMPS6_HUMAN
NC score	0.120242 (rank : 131)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

HPTR_HUMAN
NC score	0.119292 (rank : 132)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	289	Target Neighborhood Hits	166	Shared Neighborhood Hits	19
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

TMPS6_MOUSE
NC score	0.119156 (rank : 133)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	289	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

PROZ_MOUSE
NC score	0.116213 (rank : 134)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	289	Target Neighborhood Hits	410	Shared Neighborhood Hits	45
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
NC score	0.115679 (rank : 135)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	42
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA10_HUMAN
NC score	0.112329 (rank : 136)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	289	Target Neighborhood Hits	431	Shared Neighborhood Hits	45
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROC_MOUSE
NC score	0.111335 (rank : 137)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	289	Target Neighborhood Hits	426	Shared Neighborhood Hits	43
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_HUMAN
NC score	0.110604 (rank : 138)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	289	Target Neighborhood Hits	406	Shared Neighborhood Hits	41
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA10_MOUSE
NC score	0.109642 (rank : 139)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	289	Target Neighborhood Hits	435	Shared Neighborhood Hits	44
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CSPG3_MOUSE
NC score	0.106795 (rank : 140)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	289	Target Neighborhood Hits	657	Shared Neighborhood Hits	82
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FA9_HUMAN
NC score	0.104786 (rank : 141)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	289	Target Neighborhood Hits	421	Shared Neighborhood Hits	44
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

CN155_HUMAN
NC score	0.101657 (rank : 142)	θ value	3.19293e-05 (rank : 77)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	31
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

FA7_HUMAN
NC score	0.101117 (rank : 143)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	289	Target Neighborhood Hits	404	Shared Neighborhood Hits	41
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

CSPG3_HUMAN
NC score	0.100019 (rank : 144)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	289	Target Neighborhood Hits	676	Shared Neighborhood Hits	91
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CD248_MOUSE
NC score	0.099140 (rank : 145)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	289	Target Neighborhood Hits	578	Shared Neighborhood Hits	76
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

FBLN5_MOUSE
NC score	0.097552 (rank : 146)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	289	Target Neighborhood Hits	317	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

CD248_HUMAN
NC score	0.096837 (rank : 147)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	289	Target Neighborhood Hits	679	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CFAI_MOUSE
NC score	0.096159 (rank : 148)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	289	Target Neighborhood Hits	290	Shared Neighborhood Hits	34
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_HUMAN
NC score	0.095625 (rank : 149)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	289	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

C1QR1_MOUSE
NC score	0.095620 (rank : 150)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	289	Target Neighborhood Hits	342	Shared Neighborhood Hits	39
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP2_HUMAN
NC score	0.095565 (rank : 151)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	289	Target Neighborhood Hits	573	Shared Neighborhood Hits	56
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PGCA_HUMAN
NC score	0.095516 (rank : 152)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	289	Target Neighborhood Hits	821	Shared Neighborhood Hits	85
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CSPG2_MOUSE
NC score	0.095409 (rank : 153)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	289	Target Neighborhood Hits	711	Shared Neighborhood Hits	74
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

THRB_HUMAN
NC score	0.095239 (rank : 154)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	289	Target Neighborhood Hits	196	Shared Neighborhood Hits	22
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

FA7_MOUSE
NC score	0.095238 (rank : 155)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	289	Target Neighborhood Hits	374	Shared Neighborhood Hits	38
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

THRB_MOUSE
NC score	0.094196 (rank : 156)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	22
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

CSPG2_HUMAN
NC score	0.093298 (rank : 157)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	289	Target Neighborhood Hits	681	Shared Neighborhood Hits	74
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CORIN_HUMAN
NC score	0.091888 (rank : 158)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	289	Target Neighborhood Hits	453	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

FBLN5_HUMAN
NC score	0.091545 (rank : 159)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

PROS_HUMAN
NC score	0.091395 (rank : 160)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	289	Target Neighborhood Hits	340	Shared Neighborhood Hits	38
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TPA_HUMAN
NC score	0.090199 (rank : 161)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LTBP3_MOUSE
NC score	0.090047 (rank : 162)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	53
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

IL2RA_HUMAN
NC score	0.089057 (rank : 163)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

CORIN_MOUSE
NC score	0.089030 (rank : 164)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	289	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

PGCA_MOUSE
NC score	0.088692 (rank : 165)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	289	Target Neighborhood Hits	643	Shared Neighborhood Hits	67
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NETR_HUMAN
NC score	0.088483 (rank : 166)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	289	Target Neighborhood Hits	218	Shared Neighborhood Hits	25
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

MATN2_MOUSE
NC score	0.088446 (rank : 167)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	289	Target Neighborhood Hits	356	Shared Neighborhood Hits	36
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

HABP2_HUMAN
NC score	0.088195 (rank : 168)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	289	Target Neighborhood Hits	431	Shared Neighborhood Hits	39
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

NETR_MOUSE
NC score	0.088188 (rank : 169)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	289	Target Neighborhood Hits	216	Shared Neighborhood Hits	24
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

FA12_HUMAN
NC score	0.087495 (rank : 170)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	289	Target Neighborhood Hits	425	Shared Neighborhood Hits	40
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PGCB_HUMAN
NC score	0.087196 (rank : 171)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	289	Target Neighborhood Hits	478	Shared Neighborhood Hits	65
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TPA_MOUSE
NC score	0.086887 (rank : 172)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	289	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

MATN2_HUMAN
NC score	0.086427 (rank : 173)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	289	Target Neighborhood Hits	365	Shared Neighborhood Hits	36
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN2_MOUSE
NC score	0.086375 (rank : 174)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	289	Target Neighborhood Hits	505	Shared Neighborhood Hits	72
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP2_HUMAN
NC score	0.086001 (rank : 175)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	289	Target Neighborhood Hits	552	Shared Neighborhood Hits	62
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TMPS2_HUMAN
NC score	0.085845 (rank : 176)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	289	Target Neighborhood Hits	252	Shared Neighborhood Hits	31
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

MFGM_HUMAN
NC score	0.085813 (rank : 177)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	289	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

TMPS2_MOUSE
NC score	0.085392 (rank : 178)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	289	Target Neighborhood Hits	243	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

PROS_MOUSE
NC score	0.084754 (rank : 179)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	289	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

HABP2_MOUSE
NC score	0.084143 (rank : 180)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	289	Target Neighborhood Hits	445	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LDLR_HUMAN
NC score	0.084103 (rank : 181)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	289	Target Neighborhood Hits	375	Shared Neighborhood Hits	48
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

EGFL8_MOUSE
NC score	0.084094 (rank : 182)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	289	Target Neighborhood Hits	266	Shared Neighborhood Hits	28
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TMSP8_MOUSE
NC score	0.083846 (rank : 183)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TM11D_HUMAN
NC score	0.083539 (rank : 184)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

MEGF6_HUMAN
NC score	0.083266 (rank : 185)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	289	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TM11D_MOUSE
NC score	0.082794 (rank : 186)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

EDIL3_HUMAN
NC score	0.082755 (rank : 187)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	289	Target Neighborhood Hits	292	Shared Neighborhood Hits	31
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TMPS9_HUMAN
NC score	0.082699 (rank : 188)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	289	Target Neighborhood Hits	276	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

HGFA_MOUSE
NC score	0.082685 (rank : 189)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TEST_MOUSE
NC score	0.082445 (rank : 190)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TMPSD_MOUSE
NC score	0.082239 (rank : 191)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	289	Target Neighborhood Hits	334	Shared Neighborhood Hits	34
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPS9_MOUSE
NC score	0.082101 (rank : 192)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	289	Target Neighborhood Hits	296	Shared Neighborhood Hits	34
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPS4_MOUSE
NC score	0.081983 (rank : 193)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	289	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

LTBP2_MOUSE
NC score	0.081875 (rank : 194)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	289	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN2_HUMAN
NC score	0.081736 (rank : 195)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	289	Target Neighborhood Hits	392	Shared Neighborhood Hits	45
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TM11E_MOUSE
NC score	0.081698 (rank : 196)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

LRP8_MOUSE
NC score	0.081611 (rank : 197)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	289	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

HEPS_MOUSE
NC score	0.081543 (rank : 198)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TMPSD_HUMAN
NC score	0.081542 (rank : 199)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	289	Target Neighborhood Hits	333	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

MATN4_HUMAN
NC score	0.081528 (rank : 200)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	35
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

EGFL7_HUMAN
NC score	0.081513 (rank : 201)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	289	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FBN2_MOUSE
NC score	0.081314 (rank : 202)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	289	Target Neighborhood Hits	549	Shared Neighborhood Hits	51
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FA11_HUMAN
NC score	0.081289 (rank : 203)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

DESC4_MOUSE
NC score	0.081253 (rank : 204)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

PLMN_MOUSE
NC score	0.081227 (rank : 205)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	289	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

TMPS4_HUMAN
NC score	0.081175 (rank : 206)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	289	Target Neighborhood Hits	203	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

BSSP4_MOUSE
NC score	0.081132 (rank : 207)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TM11E_HUMAN
NC score	0.081126 (rank : 208)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

EDIL3_MOUSE
NC score	0.081037 (rank : 209)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	289	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

HEPS_HUMAN
NC score	0.081035 (rank : 210)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TRYG1_HUMAN
NC score	0.080924 (rank : 211)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

ACRO_HUMAN
NC score	0.080921 (rank : 212)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	289	Target Neighborhood Hits	291	Shared Neighborhood Hits	34
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

FBLN1_HUMAN
NC score	0.080802 (rank : 213)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	289	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBN2_HUMAN
NC score	0.080261 (rank : 214)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	289	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN3_MOUSE
NC score	0.080216 (rank : 215)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	289	Target Neighborhood Hits	279	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

TMPS3_HUMAN
NC score	0.080149 (rank : 216)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	289	Target Neighborhood Hits	245	Shared Neighborhood Hits	28
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

KLKB1_MOUSE
NC score	0.080093 (rank : 217)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

PRSS8_HUMAN
NC score	0.080085 (rank : 218)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

FBN1_HUMAN
NC score	0.080021 (rank : 219)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	289	Target Neighborhood Hits	557	Shared Neighborhood Hits	46
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

PRS27_HUMAN
NC score	0.079924 (rank : 220)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

HGFA_HUMAN
NC score	0.079840 (rank : 221)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	37
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FA11_MOUSE
NC score	0.079805 (rank : 222)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

ACRO_MOUSE
NC score	0.079599 (rank : 223)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TMPS3_MOUSE
NC score	0.079480 (rank : 224)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

LTBP3_HUMAN
NC score	0.079455 (rank : 225)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	289	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBN1_MOUSE
NC score	0.079228 (rank : 226)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	289	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

PLMN_HUMAN
NC score	0.079198 (rank : 227)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	289	Target Neighborhood Hits	204	Shared Neighborhood Hits	22
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

TRYG1_MOUSE
NC score	0.079001 (rank : 228)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

KLKB1_HUMAN
NC score	0.078981 (rank : 229)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	289	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

PRSS8_MOUSE
NC score	0.078948 (rank : 230)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

FBLN3_HUMAN
NC score	0.078820 (rank : 231)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	289	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LDLR_MOUSE
NC score	0.078780 (rank : 232)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	45
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

BSSP4_HUMAN
NC score	0.078708 (rank : 233)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

LRP4_MOUSE
NC score	0.078546 (rank : 234)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	289	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

APOA_HUMAN
NC score	0.078430 (rank : 235)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	289	Target Neighborhood Hits	221	Shared Neighborhood Hits	25
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

FBN3_HUMAN
NC score	0.078359 (rank : 236)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	289	Target Neighborhood Hits	543	Shared Neighborhood Hits	45
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

TEST_HUMAN
NC score	0.078350 (rank : 237)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

LRP4_HUMAN
NC score	0.078068 (rank : 238)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	289	Target Neighborhood Hits	355	Shared Neighborhood Hits	43
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

PRS27_MOUSE
NC score	0.078057 (rank : 239)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

UROK_MOUSE
NC score	0.077829 (rank : 240)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	289	Target Neighborhood Hits	273	Shared Neighborhood Hits	24
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CLCR_HUMAN
NC score	0.077812 (rank : 241)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

EGFL8_HUMAN
NC score	0.077782 (rank : 242)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	289	Target Neighborhood Hits	270	Shared Neighborhood Hits	27
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

GAS6_HUMAN
NC score	0.077408 (rank : 243)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	289	Target Neighborhood Hits	348	Shared Neighborhood Hits	36
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN4_HUMAN
NC score	0.077337 (rank : 244)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	31
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

C1QR1_HUMAN
NC score	0.077276 (rank : 245)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	289	Target Neighborhood Hits	493	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ZAN_MOUSE
NC score	0.076918 (rank : 246)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	289	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CTRL_HUMAN
NC score	0.076689 (rank : 247)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

LRP8_HUMAN
NC score	0.076651 (rank : 248)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	289	Target Neighborhood Hits	346	Shared Neighborhood Hits	43
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SON_HUMAN
NC score	0.076529 (rank : 249)	θ value	0.00134147 (rank : 95)
Query Neighborhood Hits	289	Target Neighborhood Hits	1568	Shared Neighborhood Hits	120
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

FBLN4_MOUSE
NC score	0.076390 (rank : 250)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	289	Target Neighborhood Hits	270	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN1_MOUSE
NC score	0.076344 (rank : 251)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	289	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LRP1B_HUMAN
NC score	0.076288 (rank : 252)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	289	Target Neighborhood Hits	602	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

UROK_HUMAN
NC score	0.076253 (rank : 253)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	289	Target Neighborhood Hits	272	Shared Neighborhood Hits	24
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TMPS5_HUMAN
NC score	0.075885 (rank : 254)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

LRP1B_MOUSE
NC score	0.075878 (rank : 255)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	289	Target Neighborhood Hits	606	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TRYB1_MOUSE
NC score	0.075626 (rank : 256)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

CTRB1_HUMAN
NC score	0.075622 (rank : 257)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

MATN4_MOUSE
NC score	0.075469 (rank : 258)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	289	Target Neighborhood Hits	277	Shared Neighborhood Hits	35
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

POLS2_MOUSE
NC score	0.075408 (rank : 259)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

SON_MOUSE
NC score	0.075288 (rank : 260)	θ value	0.0113563 (rank : 108)
Query Neighborhood Hits	289	Target Neighborhood Hits	957	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

TMPS5_MOUSE
NC score	0.075215 (rank : 261)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	289	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

LTB1L_HUMAN
NC score	0.074738 (rank : 262)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	289	Target Neighborhood Hits	553	Shared Neighborhood Hits	64
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MCPT6_MOUSE
NC score	0.074470 (rank : 263)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

POLS2_HUMAN
NC score	0.074306 (rank : 264)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	19
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TRYB1_HUMAN
NC score	0.073931 (rank : 265)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.073931 (rank : 266)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRY2_HUMAN
NC score	0.073711 (rank : 267)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

LTB1L_MOUSE
NC score	0.072961 (rank : 268)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	289	Target Neighborhood Hits	514	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ELA2A_MOUSE
NC score	0.072897 (rank : 269)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

KLK6_HUMAN
NC score	0.072824 (rank : 270)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

LTBP4_MOUSE
NC score	0.072744 (rank : 271)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	289	Target Neighborhood Hits	607	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1S_HUMAN
NC score	0.072467 (rank : 272)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	289	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ELA2A_HUMAN
NC score	0.072299 (rank : 273)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

PGCB_MOUSE
NC score	0.072262 (rank : 274)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	289	Target Neighborhood Hits	459	Shared Neighborhood Hits	60
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

WASF1_MOUSE
NC score	0.072210 (rank : 275)	θ value	0.00228821 (rank : 98)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

TRYA1_HUMAN
NC score	0.072150 (rank : 276)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

WASF1_HUMAN
NC score	0.072061 (rank : 277)	θ value	0.00228821 (rank : 97)
Query Neighborhood Hits	289	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

TRY2_MOUSE
NC score	0.071988 (rank : 278)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

MFGM_MOUSE
NC score	0.071774 (rank : 279)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	289	Target Neighborhood Hits	233	Shared Neighborhood Hits	18
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

KLK14_HUMAN
NC score	0.071736 (rank : 280)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

TRY1_HUMAN
NC score	0.071559 (rank : 281)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

LTB1S_MOUSE
NC score	0.071538 (rank : 282)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	289	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NRPN_HUMAN
NC score	0.071436 (rank : 283)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	289	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

TRY3_HUMAN
NC score	0.071423 (rank : 284)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

XLRS1_HUMAN
NC score	0.071120 (rank : 285)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

GAS6_MOUSE
NC score	0.071044 (rank : 286)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	289	Target Neighborhood Hits	343	Shared Neighborhood Hits	36
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRYD_HUMAN
NC score	0.070982 (rank : 287)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

KLK7_MOUSE
NC score	0.070930 (rank : 288)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK13_HUMAN
NC score	0.070866 (rank : 289)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK10_HUMAN
NC score	0.070674 (rank : 290)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

VLDLR_HUMAN
NC score	0.070547 (rank : 291)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	289	Target Neighborhood Hits	383	Shared Neighborhood Hits	45
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ELA2B_HUMAN
NC score	0.070445 (rank : 292)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

K1KB9_MOUSE
NC score	0.070317 (rank : 293)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

NRPN_MOUSE
NC score	0.070170 (rank : 294)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	18
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

PRR12_HUMAN
NC score	0.070110 (rank : 295)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	289	Target Neighborhood Hits	460	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

GRAH_HUMAN
NC score	0.070092 (rank : 296)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

LRP1_HUMAN
NC score	0.070014 (rank : 297)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	289	Target Neighborhood Hits	617	Shared Neighborhood Hits	59
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

XLRS1_MOUSE
NC score	0.069634 (rank : 298)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	289	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

KLK7_HUMAN
NC score	0.069546 (rank : 299)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

EGF_MOUSE
NC score	0.069383 (rank : 300)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	289	Target Neighborhood Hits	358	Shared Neighborhood Hits	38
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

CFAD_MOUSE
NC score	0.069159 (rank : 301)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

VLDLR_MOUSE
NC score	0.069149 (rank : 302)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	289	Target Neighborhood Hits	360	Shared Neighborhood Hits	45
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KLK12_HUMAN
NC score	0.069016 (rank : 303)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	289	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

TSP50_HUMAN
NC score	0.068987 (rank : 304)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

K1KB1_MOUSE
NC score	0.068349 (rank : 305)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

KLK11_HUMAN
NC score	0.068125 (rank : 306)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

UROM_MOUSE
NC score	0.067857 (rank : 307)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	289	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KLK1_MOUSE
NC score	0.067577 (rank : 308)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

CFAD_HUMAN
NC score	0.067436 (rank : 309)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CATG_MOUSE
NC score	0.067079 (rank : 310)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

PHXR5_MOUSE
NC score	0.067025 (rank : 311)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	289	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

KLK4_HUMAN
NC score	0.066926 (rank : 312)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
NC score	0.066839 (rank : 313)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	289	Target Neighborhood Hits	182	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK15_HUMAN
NC score	0.066801 (rank : 314)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

K1KB3_MOUSE
NC score	0.066480 (rank : 315)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	18
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

GRAM_HUMAN
NC score	0.066205 (rank : 316)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

UROL1_MOUSE
NC score	0.066163 (rank : 317)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	27
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

KLK11_MOUSE
NC score	0.065930 (rank : 318)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

K1B22_MOUSE
NC score	0.065917 (rank : 319)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1KB5_MOUSE
NC score	0.065877 (rank : 320)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

CATG_HUMAN
NC score	0.065500 (rank : 321)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CD97_HUMAN
NC score	0.065408 (rank : 322)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	289	Target Neighborhood Hits	353	Shared Neighborhood Hits	35
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR1_HUMAN
NC score	0.065317 (rank : 323)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	289	Target Neighborhood Hits	382	Shared Neighborhood Hits	43
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

KLK2_HUMAN
NC score	0.065169 (rank : 324)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

K1B11_MOUSE
NC score	0.064975 (rank : 325)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

EMR2_HUMAN
NC score	0.064923 (rank : 326)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	289	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

KLK9_HUMAN
NC score	0.064778 (rank : 327)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

K1B24_MOUSE
NC score	0.064566 (rank : 328)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	289	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

ELA1_HUMAN
NC score	0.064444 (rank : 329)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

K1B27_MOUSE
NC score	0.064348 (rank : 330)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

UROM_HUMAN
NC score	0.064035 (rank : 331)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	289	Target Neighborhood Hits	284	Shared Neighborhood Hits	31
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FA5_HUMAN
NC score	0.063835 (rank : 332)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

K1B21_MOUSE
NC score	0.063161 (rank : 333)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	289	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

RGS3_MOUSE
NC score	0.062906 (rank : 334)	θ value	0.00298849 (rank : 99)
Query Neighborhood Hits	289	Target Neighborhood Hits	1621	Shared Neighborhood Hits	119
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

LRP6_MOUSE
NC score	0.062774 (rank : 335)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	289	Target Neighborhood Hits	232	Shared Neighborhood Hits	39
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

K1KB8_MOUSE
NC score	0.062615 (rank : 336)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

EGFB2_MOUSE
NC score	0.062606 (rank : 337)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

LRP6_HUMAN
NC score	0.062481 (rank : 338)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	289	Target Neighborhood Hits	235	Shared Neighborhood Hits	39
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

KLK3_HUMAN
NC score	0.062388 (rank : 339)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	18
SwissProt Accessions	P07288, Q16272, Q86TG8	Gene names	KLK3, APS
Domain Architecture
Description	Prostate-specific antigen precursor (EC 3.4.21.77) (PSA) (Kallikrein- 3) (Semenogelase) (Gamma-seminoprotein) (Seminin) (P-30 antigen).

EGF_HUMAN
NC score	0.062190 (rank : 340)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	289	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

K1B26_MOUSE
NC score	0.061946 (rank : 341)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

ELA3A_HUMAN
NC score	0.061928 (rank : 342)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

MUC7_HUMAN
NC score	0.061779 (rank : 343)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	289	Target Neighborhood Hits	538	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

K1KB4_MOUSE
NC score	0.061684 (rank : 344)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

KLK1_HUMAN
NC score	0.061591 (rank : 345)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	289	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

CBP_HUMAN
NC score	0.061386 (rank : 346)	θ value	0.0330416 (rank : 116)
Query Neighborhood Hits	289	Target Neighborhood Hits	941	Shared Neighborhood Hits	90
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GRAD_MOUSE
NC score	0.061261 (rank : 347)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

FA8_HUMAN
NC score	0.061183 (rank : 348)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	289	Target Neighborhood Hits	112	Shared Neighborhood Hits	13
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

TRBM_HUMAN
NC score	0.061139 (rank : 349)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	289	Target Neighborhood Hits	339	Shared Neighborhood Hits	33
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

HGFL_MOUSE
NC score	0.060951 (rank : 350)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

GRAK_MOUSE
NC score	0.060935 (rank : 351)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

TRBM_MOUSE
NC score	0.060933 (rank : 352)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	32
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ELA3B_HUMAN
NC score	0.060861 (rank : 353)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

FA8_MOUSE
NC score	0.060786 (rank : 354)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	289	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

HGFL_HUMAN
NC score	0.060751 (rank : 355)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	289	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

WASIP_HUMAN
NC score	0.060564 (rank : 356)	θ value	0.365318 (rank : 139)
Query Neighborhood Hits	289	Target Neighborhood Hits	458	Shared Neighborhood Hits	44
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

GRAC_MOUSE
NC score	0.060349 (rank : 357)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

CBP_MOUSE
NC score	0.060001 (rank : 358)	θ value	0.125558 (rank : 126)
Query Neighborhood Hits	289	Target Neighborhood Hits	1051	Shared Neighborhood Hits	99
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HMCN1_HUMAN
NC score	0.059917 (rank : 359)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	289	Target Neighborhood Hits	983	Shared Neighborhood Hits	55
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

GRAE_MOUSE
NC score	0.059582 (rank : 360)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

MATN3_HUMAN
NC score	0.059514 (rank : 361)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	289	Target Neighborhood Hits	268	Shared Neighborhood Hits	31
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

GRAG_MOUSE
NC score	0.059459 (rank : 362)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	289	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAF_MOUSE
NC score	0.059416 (rank : 363)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	18
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

CO9_MOUSE
NC score	0.059288 (rank : 364)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	289	Target Neighborhood Hits	153	Shared Neighborhood Hits	21
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

MCPT2_MOUSE
NC score	0.058721 (rank : 365)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

RGS3_HUMAN
NC score	0.058597 (rank : 366)	θ value	0.00869519 (rank : 105)
Query Neighborhood Hits	289	Target Neighborhood Hits	1375	Shared Neighborhood Hits	118
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MATN1_HUMAN
NC score	0.058544 (rank : 367)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	29
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN3_MOUSE
NC score	0.058334 (rank : 368)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	289	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

WASIP_MOUSE
NC score	0.058132 (rank : 369)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	289	Target Neighborhood Hits	392	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CDN1C_HUMAN
NC score	0.057649 (rank : 370)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	289	Target Neighborhood Hits	168	Shared Neighborhood Hits	25
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

MCPT1_MOUSE
NC score	0.057643 (rank : 371)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	289	Target Neighborhood Hits	177	Shared Neighborhood Hits	18
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

EMR1_MOUSE
NC score	0.057616 (rank : 372)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	289	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CO9_HUMAN
NC score	0.057102 (rank : 373)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	289	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

OGFR_HUMAN
NC score	0.057005 (rank : 374)	θ value	0.0961366 (rank : 125)
Query Neighborhood Hits	289	Target Neighborhood Hits	1582	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

AL2S4_MOUSE
NC score	0.057000 (rank : 375)	θ value	0.0330416 (rank : 115)
Query Neighborhood Hits	289	Target Neighborhood Hits	193	Shared Neighborhood Hits	28
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

K1B16_MOUSE
NC score	0.056948 (rank : 376)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	P04071	Gene names	Klk1b16, Klk-16, Klk16
Domain Architecture
Description	Kallikrein 1-related peptidase b16 precursor (EC 3.4.21.54) (Gamma- renin, submandibular gland) (mGK-16).

NELL2_HUMAN
NC score	0.056638 (rank : 377)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	289	Target Neighborhood Hits	449	Shared Neighborhood Hits	39
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.054809 (rank : 378)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	289	Target Neighborhood Hits	436	Shared Neighborhood Hits	39
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

MCPT4_MOUSE
NC score	0.054665 (rank : 379)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

NID2_MOUSE
NC score	0.054630 (rank : 380)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	289	Target Neighborhood Hits	338	Shared Neighborhood Hits	35
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC2_MOUSE
NC score	0.054527 (rank : 381)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	289	Target Neighborhood Hits	1069	Shared Neighborhood Hits	96
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

EGFL7_MOUSE
NC score	0.054416 (rank : 382)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	289	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

MATN1_MOUSE
NC score	0.054238 (rank : 383)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	289	Target Neighborhood Hits	186	Shared Neighborhood Hits	27
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

LRP5_HUMAN
NC score	0.054032 (rank : 384)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	289	Target Neighborhood Hits	224	Shared Neighborhood Hits	35
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

HGF_HUMAN
NC score	0.053852 (rank : 385)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	289	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
NC score	0.053769 (rank : 386)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

NOTC2_HUMAN
NC score	0.053688 (rank : 387)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	289	Target Neighborhood Hits	1113	Shared Neighborhood Hits	109
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZAN_HUMAN
NC score	0.053390 (rank : 388)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	289	Target Neighborhood Hits	679	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MCPT1_HUMAN
NC score	0.053061 (rank : 389)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	289	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	P23946, Q16018	Gene names	CMA1, CYH, CYM
Domain Architecture
Description	Chymase precursor (EC 3.4.21.39) (Mast cell protease I).

STAB1_MOUSE
NC score	0.052995 (rank : 390)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	289	Target Neighborhood Hits	566	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NOTC1_MOUSE
NC score	0.052436 (rank : 391)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	289	Target Neighborhood Hits	916	Shared Neighborhood Hits	70
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MCPT8_MOUSE
NC score	0.052398 (rank : 392)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	P43430, Q9R1F1	Gene names	Mcpt8
Domain Architecture
Description	Mast cell protease 8 precursor (EC 3.4.21.-) (MMCP-8).

PCLO_HUMAN
NC score	0.052387 (rank : 393)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	289	Target Neighborhood Hits	2046	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PCLO_MOUSE
NC score	0.052386 (rank : 394)	θ value	0.0193708 (rank : 112)
Query Neighborhood Hits	289	Target Neighborhood Hits	2275	Shared Neighborhood Hits	121
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UROL1_HUMAN
NC score	0.052156 (rank : 395)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	289	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

CLC14_HUMAN
NC score	0.052024 (rank : 396)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	289	Target Neighborhood Hits	143	Shared Neighborhood Hits	23
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

MCPTX_MOUSE
NC score	0.051940 (rank : 397)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	Q00356	Gene names	Mcptl
Domain Architecture
Description	Mast cell protease-like protein precursor (EC 3.4.21.-).

NOTC3_MOUSE
NC score	0.051907 (rank : 398)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	289	Target Neighborhood Hits	975	Shared Neighborhood Hits	72
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

MCPT9_MOUSE
NC score	0.051898 (rank : 399)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	289	Target Neighborhood Hits	174	Shared Neighborhood Hits	18
SwissProt Accessions	O35164	Gene names	Mcpt9
Domain Architecture
Description	Mast cell protease 9 precursor (EC 3.4.21.-) (MMCP-9).

K1802_MOUSE
NC score	0.051673 (rank : 400)	θ value	0.0252991 (rank : 113)
Query Neighborhood Hits	289	Target Neighborhood Hits	1596	Shared Neighborhood Hits	104
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAMC2_HUMAN
NC score	0.051534 (rank : 401)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	289	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NACAM_MOUSE
NC score	0.051511 (rank : 402)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	289	Target Neighborhood Hits	1866	Shared Neighborhood Hits	126
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

STAB1_HUMAN
NC score	0.051506 (rank : 403)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	289	Target Neighborhood Hits	546	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NOTC1_HUMAN
NC score	0.051173 (rank : 404)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	289	Target Neighborhood Hits	906	Shared Neighborhood Hits	57
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CDCP1_HUMAN
NC score	0.051152 (rank : 405)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	289	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

CLC14_MOUSE
NC score	0.050639 (rank : 406)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	289	Target Neighborhood Hits	120	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

MCPT5_MOUSE
NC score	0.050628 (rank : 407)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	289	Target Neighborhood Hits	175	Shared Neighborhood Hits	17
SwissProt Accessions	P21844, Q9R1F0	Gene names	Mcpt5
Domain Architecture
Description	Mast cell protease 5 precursor (EC 3.4.21.-) (MMCP-5) (Mast cell chymase 1).

MLL3_HUMAN
NC score	0.050497 (rank : 408)	θ value	0.0563607 (rank : 120)
Query Neighborhood Hits	289	Target Neighborhood Hits	1644	Shared Neighborhood Hits	109
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NOTC3_HUMAN
NC score	0.050435 (rank : 409)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	289	Target Neighborhood Hits	1062	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CNTP3_HUMAN
NC score	0.048360 (rank : 410)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	289	Target Neighborhood Hits	195	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

BAT2_HUMAN
NC score	0.046562 (rank : 411)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	289	Target Neighborhood Hits	931	Shared Neighborhood Hits	79
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WASF3_MOUSE
NC score	0.044878 (rank : 412)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	289	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHI6	Gene names	Wasf3, Wave3
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3).

YLPM1_HUMAN
NC score	0.044740 (rank : 413)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	289	Target Neighborhood Hits	670	Shared Neighborhood Hits	58
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MLL2_HUMAN
NC score	0.044248 (rank : 414)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	289	Target Neighborhood Hits	1788	Shared Neighborhood Hits	102
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ALEX_HUMAN
NC score	0.044136 (rank : 415)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	289	Target Neighborhood Hits	361	Shared Neighborhood Hits	44
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

MLL3_MOUSE
NC score	0.044122 (rank : 416)	θ value	2.36792 (rank : 187)
Query Neighborhood Hits	289	Target Neighborhood Hits	1399	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BAT2_MOUSE
NC score	0.043779 (rank : 417)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	289	Target Neighborhood Hits	947	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SGIP1_HUMAN
NC score	0.043193 (rank : 418)	θ value	2.36792 (rank : 193)
Query Neighborhood Hits	289	Target Neighborhood Hits	198	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM1_MOUSE
NC score	0.042445 (rank : 419)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	289	Target Neighborhood Hits	966	Shared Neighborhood Hits	73
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MLL4_HUMAN
NC score	0.042165 (rank : 420)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	289	Target Neighborhood Hits	722	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PRG4_MOUSE
NC score	0.042142 (rank : 421)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	289	Target Neighborhood Hits	624	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NELFA_HUMAN
NC score	0.041705 (rank : 422)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	289	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

BAT3_MOUSE
NC score	0.041474 (rank : 423)	θ value	3.0926 (rank : 197)
Query Neighborhood Hits	289	Target Neighborhood Hits	518	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

NFH_MOUSE
NC score	0.039761 (rank : 424)	θ value	9.29e-05 (rank : 84)
Query Neighborhood Hits	289	Target Neighborhood Hits	2247	Shared Neighborhood Hits	104
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

K1802_HUMAN
NC score	0.039530 (rank : 425)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	289	Target Neighborhood Hits	1378	Shared Neighborhood Hits	93
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BRD4_HUMAN
NC score	0.038595 (rank : 426)	θ value	0.47712 (rank : 140)
Query Neighborhood Hits	289	Target Neighborhood Hits	851	Shared Neighborhood Hits	54
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PI5PA_HUMAN
NC score	0.038510 (rank : 427)	θ value	2.36792 (rank : 189)
Query Neighborhood Hits	289	Target Neighborhood Hits	749	Shared Neighborhood Hits	86
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

BRD4_MOUSE
NC score	0.038421 (rank : 428)	θ value	1.06291 (rank : 154)
Query Neighborhood Hits	289	Target Neighborhood Hits	845	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

NRX2A_HUMAN
NC score	0.037973 (rank : 429)	θ value	3.0926 (rank : 202)
Query Neighborhood Hits	289	Target Neighborhood Hits	614	Shared Neighborhood Hits	78
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

SAPS1_HUMAN
NC score	0.037266 (rank : 430)	θ value	2.36792 (rank : 191)
Query Neighborhood Hits	289	Target Neighborhood Hits	704	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SYN1_HUMAN
NC score	0.036925 (rank : 431)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	289	Target Neighborhood Hits	419	Shared Neighborhood Hits	46
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

RFX1_HUMAN
NC score	0.036001 (rank : 432)	θ value	0.365318 (rank : 137)
Query Neighborhood Hits	289	Target Neighborhood Hits	256	Shared Neighborhood Hits	34
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SYNJ1_MOUSE
NC score	0.035824 (rank : 433)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	289	Target Neighborhood Hits	516	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ENAH_MOUSE
NC score	0.035463 (rank : 434)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	289	Target Neighborhood Hits	919	Shared Neighborhood Hits	60
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SFR15_HUMAN
NC score	0.034254 (rank : 435)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	289	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ATX2L_HUMAN
NC score	0.033307 (rank : 436)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	289	Target Neighborhood Hits	443	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

MINT_MOUSE
NC score	0.033218 (rank : 437)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	289	Target Neighborhood Hits	1514	Shared Neighborhood Hits	91
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NRX1A_MOUSE
NC score	0.032345 (rank : 438)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	289	Target Neighborhood Hits	164	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_HUMAN
NC score	0.032235 (rank : 439)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	289	Target Neighborhood Hits	170	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PO121_HUMAN
NC score	0.031985 (rank : 440)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	289	Target Neighborhood Hits	344	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

CRTC1_MOUSE
NC score	0.031876 (rank : 441)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	289	Target Neighborhood Hits	230	Shared Neighborhood Hits	34
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

TM108_MOUSE
NC score	0.031542 (rank : 442)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	289	Target Neighborhood Hits	336	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

NFAC1_HUMAN
NC score	0.030226 (rank : 443)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	289	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NCOR2_HUMAN
NC score	0.029902 (rank : 444)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	289	Target Neighborhood Hits	870	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RERE_MOUSE
NC score	0.029876 (rank : 445)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	289	Target Neighborhood Hits	785	Shared Neighborhood Hits	52
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NSD1_MOUSE
NC score	0.028342 (rank : 446)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	289	Target Neighborhood Hits	472	Shared Neighborhood Hits	37
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TCOF_HUMAN
NC score	0.028332 (rank : 447)	θ value	4.03905 (rank : 216)
Query Neighborhood Hits	289	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MAP1A_HUMAN
NC score	0.028239 (rank : 448)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	289	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CIC_MOUSE
NC score	0.028127 (rank : 449)	θ value	3.0926 (rank : 198)
Query Neighborhood Hits	289	Target Neighborhood Hits	742	Shared Neighborhood Hits	69
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

COIA1_HUMAN
NC score	0.028069 (rank : 450)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	289	Target Neighborhood Hits	447	Shared Neighborhood Hits	46
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

RERE_HUMAN
NC score	0.028052 (rank : 451)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	289	Target Neighborhood Hits	779	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SFPQ_MOUSE
NC score	0.027920 (rank : 452)	θ value	2.36792 (rank : 192)
Query Neighborhood Hits	289	Target Neighborhood Hits	958	Shared Neighborhood Hits	49
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

COIA1_MOUSE
NC score	0.027336 (rank : 453)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	289	Target Neighborhood Hits	481	Shared Neighborhood Hits	52
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

PDC6I_MOUSE
NC score	0.027015 (rank : 454)	θ value	1.81305 (rank : 177)
Query Neighborhood Hits	289	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

RFX1_MOUSE
NC score	0.026005 (rank : 455)	θ value	2.36792 (rank : 190)
Query Neighborhood Hits	289	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

PELP1_HUMAN
NC score	0.024622 (rank : 456)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	289	Target Neighborhood Hits	596	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

3BP1_HUMAN
NC score	0.024133 (rank : 457)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	289	Target Neighborhood Hits	376	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TCGAP_HUMAN
NC score	0.024074 (rank : 458)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	289	Target Neighborhood Hits	872	Shared Neighborhood Hits	80
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PDC6I_HUMAN
NC score	0.023978 (rank : 459)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

IL3B2_MOUSE
NC score	0.023747 (rank : 460)	θ value	6.88961 (rank : 241)
Query Neighborhood Hits	289	Target Neighborhood Hits	372	Shared Neighborhood Hits	53
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

SHAN1_HUMAN
NC score	0.023706 (rank : 461)	θ value	0.0330416 (rank : 118)
Query Neighborhood Hits	289	Target Neighborhood Hits	1041	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

NSD1_HUMAN
NC score	0.023638 (rank : 462)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

COHA1_MOUSE
NC score	0.023570 (rank : 463)	θ value	1.38821 (rank : 161)
Query Neighborhood Hits	289	Target Neighborhood Hits	414	Shared Neighborhood Hits	39
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

PDCD7_HUMAN
NC score	0.023529 (rank : 464)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	289	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

GORS2_MOUSE
NC score	0.023081 (rank : 465)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	289	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JX3, Q3U9D2, Q8CCD0, Q91W68	Gene names	Gorasp2
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55).

BRD8_MOUSE
NC score	0.023048 (rank : 466)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	289	Target Neighborhood Hits	422	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ABI3_HUMAN
NC score	0.022941 (rank : 467)	θ value	1.38821 (rank : 160)
Query Neighborhood Hits	289	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

GP112_HUMAN
NC score	0.021477 (rank : 468)	θ value	0.62314 (rank : 142)
Query Neighborhood Hits	289	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

CO1A1_MOUSE
NC score	0.021447 (rank : 469)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	289	Target Neighborhood Hits	457	Shared Neighborhood Hits	40
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

COEA1_HUMAN
NC score	0.021393 (rank : 470)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	289	Target Neighborhood Hits	427	Shared Neighborhood Hits	41
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CO1A1_HUMAN
NC score	0.021346 (rank : 471)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	289	Target Neighborhood Hits	475	Shared Neighborhood Hits	42
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CT175_HUMAN
NC score	0.021175 (rank : 472)	θ value	3.0926 (rank : 199)
Query Neighborhood Hits	289	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MK2, Q5QPB6, Q9NQQ2	Gene names	C20orf175
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf175.

ZYX_MOUSE
NC score	0.020827 (rank : 473)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	289	Target Neighborhood Hits	347	Shared Neighborhood Hits	25
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

FRAS1_MOUSE
NC score	0.020819 (rank : 474)	θ value	3.0926 (rank : 200)
Query Neighborhood Hits	289	Target Neighborhood Hits	747	Shared Neighborhood Hits	31
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FMNL_MOUSE
NC score	0.020454 (rank : 475)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	289	Target Neighborhood Hits	428	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

WHRN_MOUSE
NC score	0.020281 (rank : 476)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	289	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

GNAS1_HUMAN
NC score	0.020126 (rank : 477)	θ value	0.0961366 (rank : 124)
Query Neighborhood Hits	289	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

DNL1_HUMAN
NC score	0.020069 (rank : 478)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	289	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DYN2_MOUSE
NC score	0.019633 (rank : 479)	θ value	0.125558 (rank : 127)
Query Neighborhood Hits	289	Target Neighborhood Hits	104	Shared Neighborhood Hits	11
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

ABI3_MOUSE
NC score	0.019251 (rank : 480)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	289	Target Neighborhood Hits	227	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

JIP2_HUMAN
NC score	0.018182 (rank : 481)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	289	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

TULP4_MOUSE
NC score	0.017743 (rank : 482)	θ value	2.36792 (rank : 195)
Query Neighborhood Hits	289	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

RP1L1_HUMAN
NC score	0.017584 (rank : 483)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	289	Target Neighborhood Hits	1072	Shared Neighborhood Hits	58
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

COAA1_HUMAN
NC score	0.017264 (rank : 484)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	289	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

IRS2_MOUSE
NC score	0.017084 (rank : 485)	θ value	6.88961 (rank : 242)
Query Neighborhood Hits	289	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

TNR25_HUMAN
NC score	0.016601 (rank : 486)	θ value	2.36792 (rank : 194)
Query Neighborhood Hits	289	Target Neighborhood Hits	172	Shared Neighborhood Hits	9
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

NCOR1_MOUSE
NC score	0.016591 (rank : 487)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	289	Target Neighborhood Hits	521	Shared Neighborhood Hits	24
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

GGA1_MOUSE
NC score	0.016530 (rank : 488)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	289	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

DAB2_MOUSE
NC score	0.016389 (rank : 489)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	289	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

CO4A4_HUMAN
NC score	0.015911 (rank : 490)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	289	Target Neighborhood Hits	440	Shared Neighborhood Hits	35
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

PSD4_HUMAN
NC score	0.015867 (rank : 491)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	289	Target Neighborhood Hits	178	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

CONA1_MOUSE
NC score	0.015384 (rank : 492)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	289	Target Neighborhood Hits	254	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4G2, Q5SUQ0	Gene names	Col23a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

WBS14_MOUSE
NC score	0.015279 (rank : 493)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	289	Target Neighborhood Hits	171	Shared Neighborhood Hits	21
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

BRD9_MOUSE
NC score	0.014922 (rank : 494)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	289	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

CA106_HUMAN
NC score	0.014657 (rank : 495)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	289	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

NCA11_MOUSE
NC score	0.014118 (rank : 496)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	289	Target Neighborhood Hits	661	Shared Neighborhood Hits	39
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

GGA1_HUMAN
NC score	0.013993 (rank : 497)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	289	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

HGS_MOUSE
NC score	0.013765 (rank : 498)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	289	Target Neighborhood Hits	589	Shared Neighborhood Hits	41
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

IASPP_HUMAN
NC score	0.013723 (rank : 499)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	289	Target Neighborhood Hits	688	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IL4RA_HUMAN
NC score	0.013486 (rank : 500)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	289	Target Neighborhood Hits	144	Shared Neighborhood Hits	20
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

IL12B_HUMAN
NC score	0.013198 (rank : 501)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	289	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

MKL2_HUMAN
NC score	0.012874 (rank : 502)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	289	Target Neighborhood Hits	274	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

CSKI2_HUMAN
NC score	0.012844 (rank : 503)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	289	Target Neighborhood Hits	747	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

MAGI2_HUMAN
NC score	0.012640 (rank : 504)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	289	Target Neighborhood Hits	373	Shared Neighborhood Hits	24
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

ROBO1_MOUSE
NC score	0.012559 (rank : 505)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	289	Target Neighborhood Hits	559	Shared Neighborhood Hits	16
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

ROBO1_HUMAN
NC score	0.012230 (rank : 506)	θ value	0.21417 (rank : 134)
Query Neighborhood Hits	289	Target Neighborhood Hits	529	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

EMIL1_HUMAN
NC score	0.012142 (rank : 507)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

PO6F2_MOUSE
NC score	0.011855 (rank : 508)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	289	Target Neighborhood Hits	639	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PAPOA_MOUSE
NC score	0.011350 (rank : 509)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	289	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

CAC1B_HUMAN
NC score	0.010761 (rank : 510)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	289	Target Neighborhood Hits	257	Shared Neighborhood Hits	9
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PDXL2_HUMAN
NC score	0.010368 (rank : 511)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	289	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ53, Q6UVY4, Q8WUV6	Gene names	PODXL2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

SNX15_MOUSE
NC score	0.009595 (rank : 512)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	289	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WE1	Gene names	Snx15
Domain Architecture	No domain graphic available
Description	Sorting nexin-15.

SF3B4_HUMAN
NC score	0.009363 (rank : 513)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	289	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

RIMB1_HUMAN
NC score	0.009333 (rank : 514)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	289	Target Neighborhood Hits	1479	Shared Neighborhood Hits	66
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RTN2_MOUSE
NC score	0.009098 (rank : 515)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	289	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O70622, O70620	Gene names	Rtn2, Nspl1
Domain Architecture
Description	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (NSPLI).

RTP4_HUMAN
NC score	0.008639 (rank : 516)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q96DX8, Q9H4F3	Gene names	RTP4, IFRG28
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 4 (28 kDa interferon-responsive protein).

NEURL_MOUSE
NC score	0.008301 (rank : 517)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	289	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
NC score	0.008245 (rank : 518)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	289	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

S29A3_HUMAN
NC score	0.007605 (rank : 519)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	289	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZD2, Q7RTT8, Q8IVZ0	Gene names	SLC29A3, ENT3
Domain Architecture
Description	Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3).

ASPP2_HUMAN
NC score	0.007368 (rank : 520)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	289	Target Neighborhood Hits	1156	Shared Neighborhood Hits	46
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

RECQ4_MOUSE
NC score	0.007277 (rank : 521)	θ value	4.03905 (rank : 215)
Query Neighborhood Hits	289	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SDK1_MOUSE
NC score	0.006670 (rank : 522)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	289	Target Neighborhood Hits	495	Shared Neighborhood Hits	14
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

KCNH2_HUMAN
NC score	0.006568 (rank : 523)	θ value	3.0926 (rank : 201)
Query Neighborhood Hits	289	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

NXPH2_MOUSE
NC score	0.006487 (rank : 524)	θ value	6.88961 (rank : 243)
Query Neighborhood Hits	289	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61199, Q8BIN8	Gene names	Nxph2, Nph2
Domain Architecture	No domain graphic available
Description	Neurexophilin-2 precursor.

ENPP2_MOUSE
NC score	0.006426 (rank : 525)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	289	Target Neighborhood Hits	66	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

STAU2_MOUSE
NC score	0.006184 (rank : 526)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	289	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJ67, Q8BSY8, Q8CJ66, Q8R175, Q91Z19, Q9D5N7	Gene names	Stau2
Domain Architecture	No domain graphic available
Description	Double-stranded RNA-binding protein Staufen homolog 2.

SDK1_HUMAN
NC score	0.006130 (rank : 527)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	289	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NRCAM_MOUSE
NC score	0.006038 (rank : 528)	θ value	2.36792 (rank : 188)
Query Neighborhood Hits	289	Target Neighborhood Hits	432	Shared Neighborhood Hits	9
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

IRF5_MOUSE
NC score	0.005939 (rank : 529)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	289	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

GRIPE_MOUSE
NC score	0.005270 (rank : 530)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	289	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TITIN_HUMAN
NC score	0.005131 (rank : 531)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	289	Target Neighborhood Hits	2923	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DDFL1_HUMAN
NC score	0.004302 (rank : 532)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	289	Target Neighborhood Hits	353	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

SL9A3_HUMAN
NC score	0.003968 (rank : 533)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	289	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

FOXJ2_HUMAN
NC score	0.003922 (rank : 534)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	289	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

WNK2_HUMAN
NC score	0.003708 (rank : 535)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	289	Target Neighborhood Hits	1407	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CEND3_MOUSE
NC score	0.003654 (rank : 536)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	289	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

HDAC6_HUMAN
NC score	0.003405 (rank : 537)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	289	Target Neighborhood Hits	145	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

PTPRN_MOUSE
NC score	0.003212 (rank : 538)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	289	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

AAK1_HUMAN
NC score	0.002859 (rank : 539)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	289	Target Neighborhood Hits	1077	Shared Neighborhood Hits	56
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ATS20_HUMAN
NC score	0.002425 (rank : 540)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	289	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CRX_MOUSE
NC score	0.002265 (rank : 541)	θ value	1.38821 (rank : 162)
Query Neighborhood Hits	289	Target Neighborhood Hits	359	Shared Neighborhood Hits	9
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

CTGE5_HUMAN
NC score	0.002262 (rank : 542)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	289	Target Neighborhood Hits	800	Shared Neighborhood Hits	17
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

ERCC6_HUMAN
NC score	0.002110 (rank : 543)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	289	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

CXA8_MOUSE
NC score	0.001114 (rank : 544)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	289	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P28236	Gene names	Gja8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

RREB1_HUMAN
NC score	0.000901 (rank : 545)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	289	Target Neighborhood Hits	879	Shared Neighborhood Hits	24
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

HXB2_HUMAN
NC score	0.000559 (rank : 546)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	289	Target Neighborhood Hits	367	Shared Neighborhood Hits	13
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

SALL3_HUMAN
NC score	0.000228 (rank : 547)	θ value	3.0926 (rank : 204)
Query Neighborhood Hits	289	Target Neighborhood Hits	1066	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

TSK_HUMAN
NC score	0.000012 (rank : 548)	θ value	4.03905 (rank : 217)
Query Neighborhood Hits	289	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUA8, Q6UXK1, Q9UG10, Q9UJX9	Gene names	LRRC54, E2IG4, TSK
Domain Architecture	No domain graphic available
Description	Tsukushi precursor (Leucine-rich repeat-containing protein 54) (E2- induced gene 4 protein).

LATS1_MOUSE
NC score	-0.000429 (rank : 549)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	289	Target Neighborhood Hits	1027	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

HME1_MOUSE
NC score	-0.001167 (rank : 550)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	289	Target Neighborhood Hits	397	Shared Neighborhood Hits	16
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

GLI2_HUMAN
NC score	-0.001932 (rank : 551)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	289	Target Neighborhood Hits	971	Shared Neighborhood Hits	34
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

LATS1_HUMAN
NC score	-0.002265 (rank : 552)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	289	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

PAK4_MOUSE
NC score	-0.004197 (rank : 553)	θ value	3.0926 (rank : 203)
Query Neighborhood Hits	289	Target Neighborhood Hits	1098	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

M3K11_HUMAN
NC score	-0.004851 (rank : 554)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	289	Target Neighborhood Hits	1136	Shared Neighborhood Hits	35
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ZBT7A_MOUSE
NC score	-0.005481 (rank : 555)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	289	Target Neighborhood Hits	795	Shared Neighborhood Hits	8
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).

PAK6_HUMAN
NC score	-0.006196 (rank : 556)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	289	Target Neighborhood Hits	915	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

ZN132_HUMAN
NC score	-0.006664 (rank : 557)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	289	Target Neighborhood Hits	752	Shared Neighborhood Hits	9
SwissProt Accessions	P52740	Gene names	ZNF132
Domain Architecture	No domain graphic available
Description	Zinc finger protein 132.

RET_MOUSE
NC score	-0.007610 (rank : 558)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	289	Target Neighborhood Hits	884	Shared Neighborhood Hits	12
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

MRCKB_MOUSE
NC score	-0.008349 (rank : 559)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	289	Target Neighborhood Hits	2180	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).