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Network neighborhood for query Sequence : GGA1_HUMAN

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GGA1_HUMAN
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GGA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	169	Target Neighborhood Hits	169	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
θ value	0 (rank : 2)	NC score	0.975245 (rank : 2)
Query Neighborhood Hits	169	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_HUMAN
θ value	3.4016e-132 (rank : 3)	NC score	0.949589 (rank : 4)
Query Neighborhood Hits	169	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
θ value	2.06847e-121 (rank : 4)	NC score	0.952646 (rank : 3)
Query Neighborhood Hits	169	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA3_MOUSE
θ value	1.29861e-115 (rank : 5)	NC score	0.931614 (rank : 6)
Query Neighborhood Hits	169	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_HUMAN
θ value	2.44908e-114 (rank : 6)	NC score	0.943656 (rank : 5)
Query Neighborhood Hits	169	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TOM1_MOUSE
θ value	7.0802e-21 (rank : 7)	NC score	0.687548 (rank : 7)
Query Neighborhood Hits	169	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
θ value	1.2077e-20 (rank : 8)	NC score	0.682721 (rank : 8)
Query Neighborhood Hits	169	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TM1L1_MOUSE
θ value	1.16975e-15 (rank : 9)	NC score	0.652311 (rank : 9)
Query Neighborhood Hits	169	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

AP1G1_HUMAN
θ value	1.29331e-14 (rank : 10)	NC score	0.367836 (rank : 17)
Query Neighborhood Hits	169	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

TM1L1_HUMAN
θ value	6.41864e-14 (rank : 11)	NC score	0.639318 (rank : 10)
Query Neighborhood Hits	169	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

AP1G1_MOUSE
θ value	3.52202e-12 (rank : 12)	NC score	0.358548 (rank : 18)
Query Neighborhood Hits	169	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

HGS_MOUSE
θ value	1.02475e-11 (rank : 13)	NC score	0.405825 (rank : 11)
Query Neighborhood Hits	169	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	1.74796e-11 (rank : 14)	NC score	0.404895 (rank : 12)
Query Neighborhood Hits	169	Target Neighborhood Hits	517	Shared Neighborhood Hits	47
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STAM1_MOUSE
θ value	1.9326e-10 (rank : 15)	NC score	0.384835 (rank : 15)
Query Neighborhood Hits	169	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_HUMAN
θ value	3.29651e-10 (rank : 16)	NC score	0.389598 (rank : 14)
Query Neighborhood Hits	169	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

AP1G2_MOUSE
θ value	5.62301e-10 (rank : 17)	NC score	0.348564 (rank : 19)
Query Neighborhood Hits	169	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

STAM2_HUMAN
θ value	3.64472e-09 (rank : 18)	NC score	0.395639 (rank : 13)
Query Neighborhood Hits	169	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	6.21693e-09 (rank : 19)	NC score	0.381041 (rank : 16)
Query Neighborhood Hits	169	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

AP1G2_HUMAN
θ value	1.06045e-08 (rank : 20)	NC score	0.339757 (rank : 20)
Query Neighborhood Hits	169	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

ASPP2_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.040146 (rank : 44)
Query Neighborhood Hits	169	Target Neighborhood Hits	1156	Shared Neighborhood Hits	59
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

STMN1_MOUSE
θ value	0.00869519 (rank : 22)	NC score	0.071891 (rank : 29)
Query Neighborhood Hits	169	Target Neighborhood Hits	560	Shared Neighborhood Hits	24
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

CJ012_HUMAN
θ value	0.0113563 (rank : 23)	NC score	0.071133 (rank : 31)
Query Neighborhood Hits	169	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MLL3_MOUSE
θ value	0.0148317 (rank : 24)	NC score	0.059119 (rank : 32)
Query Neighborhood Hits	169	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
θ value	0.0252991 (rank : 25)	NC score	0.059046 (rank : 33)
Query Neighborhood Hits	169	Target Neighborhood Hits	1644	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

STMN1_HUMAN
θ value	0.0252991 (rank : 26)	NC score	0.071231 (rank : 30)
Query Neighborhood Hits	169	Target Neighborhood Hits	554	Shared Neighborhood Hits	24
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

DACH1_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.038052 (rank : 47)
Query Neighborhood Hits	169	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

EPN1_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.040766 (rank : 42)
Query Neighborhood Hits	169	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

FOSB_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.030097 (rank : 63)
Query Neighborhood Hits	169	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

PTPRD_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.014909 (rank : 126)
Query Neighborhood Hits	169	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

ROCK1_MOUSE
θ value	0.21417 (rank : 31)	NC score	0.015290 (rank : 124)
Query Neighborhood Hits	169	Target Neighborhood Hits	2126	Shared Neighborhood Hits	51
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

RTN4_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.043702 (rank : 40)
Query Neighborhood Hits	169	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

T22D4_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.058063 (rank : 34)
Query Neighborhood Hits	169	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

RD23B_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.028950 (rank : 71)
Query Neighborhood Hits	169	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

ROCK1_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.017320 (rank : 116)
Query Neighborhood Hits	169	Target Neighborhood Hits	2000	Shared Neighborhood Hits	49
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

AZI1_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.030323 (rank : 62)
Query Neighborhood Hits	169	Target Neighborhood Hits	1000	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

COEA1_MOUSE
θ value	0.365318 (rank : 37)	NC score	0.022582 (rank : 93)
Query Neighborhood Hits	169	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DIAP1_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.025881 (rank : 78)
Query Neighborhood Hits	169	Target Neighborhood Hits	784	Shared Neighborhood Hits	40
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EPN1_MOUSE
θ value	0.365318 (rank : 39)	NC score	0.038091 (rank : 46)
Query Neighborhood Hits	169	Target Neighborhood Hits	240	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

SHAN1_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.024638 (rank : 83)
Query Neighborhood Hits	169	Target Neighborhood Hits	1041	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DMD_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.029454 (rank : 66)
Query Neighborhood Hits	169	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LR37A_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.037123 (rank : 49)
Query Neighborhood Hits	169	Target Neighborhood Hits	720	Shared Neighborhood Hits	42
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

RTP3_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.036468 (rank : 51)
Query Neighborhood Hits	169	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

WASL_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.037009 (rank : 50)
Query Neighborhood Hits	169	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

BRSK2_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.003907 (rank : 169)
Query Neighborhood Hits	169	Target Neighborhood Hits	897	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

COEA1_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.021144 (rank : 96)
Query Neighborhood Hits	169	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

NSD1_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.028820 (rank : 72)
Query Neighborhood Hits	169	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PTPRD_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.014121 (rank : 130)
Query Neighborhood Hits	169	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

RTN4_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.035920 (rank : 52)
Query Neighborhood Hits	169	Target Neighborhood Hits	357	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SOCS7_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.024074 (rank : 86)
Query Neighborhood Hits	169	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

ANGL5_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.019486 (rank : 103)
Query Neighborhood Hits	169	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

CNOT4_MOUSE
θ value	0.813845 (rank : 52)	NC score	0.043855 (rank : 39)
Query Neighborhood Hits	169	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CO4A5_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.018253 (rank : 112)
Query Neighborhood Hits	169	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

GPTC8_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.032077 (rank : 60)
Query Neighborhood Hits	169	Target Neighborhood Hits	366	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SMCA4_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.024797 (rank : 81)
Query Neighborhood Hits	169	Target Neighborhood Hits	597	Shared Neighborhood Hits	40
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SRRM2_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.037329 (rank : 48)
Query Neighborhood Hits	169	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYCP1_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.032682 (rank : 57)
Query Neighborhood Hits	169	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

DCC_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.022582 (rank : 92)
Query Neighborhood Hits	169	Target Neighborhood Hits	896	Shared Neighborhood Hits	49
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

IF39_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.022803 (rank : 89)
Query Neighborhood Hits	169	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

KINH_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.018751 (rank : 106)
Query Neighborhood Hits	169	Target Neighborhood Hits	1231	Shared Neighborhood Hits	40
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

SYGP1_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.024841 (rank : 80)
Query Neighborhood Hits	169	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

TACC2_MOUSE
θ value	1.06291 (rank : 62)	NC score	0.026362 (rank : 76)
Query Neighborhood Hits	169	Target Neighborhood Hits	774	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

WASIP_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.044539 (rank : 38)
Query Neighborhood Hits	169	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

BTBDC_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.029143 (rank : 70)
Query Neighborhood Hits	169	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

DMD_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.029376 (rank : 68)
Query Neighborhood Hits	169	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

HCLS1_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.040503 (rank : 43)
Query Neighborhood Hits	169	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

K1958_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.028132 (rank : 73)
Query Neighborhood Hits	169	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MUC7_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.044829 (rank : 37)
Query Neighborhood Hits	169	Target Neighborhood Hits	538	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RGS3_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.029828 (rank : 64)
Query Neighborhood Hits	169	Target Neighborhood Hits	1375	Shared Neighborhood Hits	78
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SET1A_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.047769 (rank : 35)
Query Neighborhood Hits	169	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SYNJ1_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.020157 (rank : 99)
Query Neighborhood Hits	169	Target Neighborhood Hits	498	Shared Neighborhood Hits	39
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZBTB3_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.004359 (rank : 168)
Query Neighborhood Hits	169	Target Neighborhood Hits	910	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

HNRL1_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.022652 (rank : 90)
Query Neighborhood Hits	169	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

MBD6_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.045465 (rank : 36)
Query Neighborhood Hits	169	Target Neighborhood Hits	349	Shared Neighborhood Hits	32
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PF21B_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.025184 (rank : 79)
Query Neighborhood Hits	169	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SALL3_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.005033 (rank : 162)
Query Neighborhood Hits	169	Target Neighborhood Hits	1066	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SAPS1_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.034177 (rank : 55)
Query Neighborhood Hits	169	Target Neighborhood Hits	704	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

YTHD1_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.018413 (rank : 108)
Query Neighborhood Hits	169	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

ZBTB4_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.003243 (rank : 172)
Query Neighborhood Hits	169	Target Neighborhood Hits	926	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

ARMC4_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.035626 (rank : 53)
Query Neighborhood Hits	169	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

BAT3_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.027678 (rank : 74)
Query Neighborhood Hits	169	Target Neighborhood Hits	490	Shared Neighborhood Hits	38
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CIC_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.042719 (rank : 41)
Query Neighborhood Hits	169	Target Neighborhood Hits	992	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LRC45_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.026286 (rank : 77)
Query Neighborhood Hits	169	Target Neighborhood Hits	933	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MRCKA_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.012068 (rank : 136)
Query Neighborhood Hits	169	Target Neighborhood Hits	1999	Shared Neighborhood Hits	47
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

NCOA6_MOUSE
θ value	2.36792 (rank : 85)	NC score	0.038358 (rank : 45)
Query Neighborhood Hits	169	Target Neighborhood Hits	1076	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

UTRO_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.023260 (rank : 87)
Query Neighborhood Hits	169	Target Neighborhood Hits	960	Shared Neighborhood Hits	35
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

BORG5_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.018440 (rank : 107)
Query Neighborhood Hits	169	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

CASL_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.022615 (rank : 91)
Query Neighborhood Hits	169	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CENPE_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.020220 (rank : 97)
Query Neighborhood Hits	169	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CO9A3_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.011215 (rank : 138)
Query Neighborhood Hits	169	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

DDX21_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.004767 (rank : 164)
Query Neighborhood Hits	169	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

LIRB5_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.006374 (rank : 157)
Query Neighborhood Hits	169	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	O75023, Q8N760	Gene names	LILRB5, LIR8
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor (Leukocyte immunoglobulin-like receptor 8) (LIR-8) (CD85c antigen).

NCOR1_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.018305 (rank : 109)
Query Neighborhood Hits	169	Target Neighborhood Hits	577	Shared Neighborhood Hits	32
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

SF01_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.029405 (rank : 67)
Query Neighborhood Hits	169	Target Neighborhood Hits	287	Shared Neighborhood Hits	25
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SYN2_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.021331 (rank : 95)
Query Neighborhood Hits	169	Target Neighborhood Hits	213	Shared Neighborhood Hits	22
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

WASF2_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.020179 (rank : 98)
Query Neighborhood Hits	169	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

BPAEA_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.018304 (rank : 110)
Query Neighborhood Hits	169	Target Neighborhood Hits	1480	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

FOXP4_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.009325 (rank : 146)
Query Neighborhood Hits	169	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

KRHB5_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.008935 (rank : 149)
Query Neighborhood Hits	169	Target Neighborhood Hits	321	Shared Neighborhood Hits	13
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

MAGI2_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.009654 (rank : 144)
Query Neighborhood Hits	169	Target Neighborhood Hits	373	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MGRN1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.012897 (rank : 133)
Query Neighborhood Hits	169	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

NMDE4_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.005073 (rank : 161)
Query Neighborhood Hits	169	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

OBSCN_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.008705 (rank : 150)
Query Neighborhood Hits	169	Target Neighborhood Hits	1931	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PHLPP_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.005124 (rank : 160)
Query Neighborhood Hits	169	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PTN23_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.021678 (rank : 94)
Query Neighborhood Hits	169	Target Neighborhood Hits	646	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SYP2L_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.017437 (rank : 115)
Query Neighborhood Hits	169	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TENS1_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.016937 (rank : 118)
Query Neighborhood Hits	169	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TM16H_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.014390 (rank : 128)
Query Neighborhood Hits	169	Target Neighborhood Hits	139	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

WEE1_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.003873 (rank : 170)
Query Neighborhood Hits	169	Target Neighborhood Hits	777	Shared Neighborhood Hits	14
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

ASXL1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.014512 (rank : 127)
Query Neighborhood Hits	169	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ATBF1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.006054 (rank : 158)
Query Neighborhood Hits	169	Target Neighborhood Hits	1547	Shared Neighborhood Hits	41
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ELL2_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.012700 (rank : 134)
Query Neighborhood Hits	169	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	O00472	Gene names	ELL2
Domain Architecture
Description	RNA polymerase II elongation factor ELL2.

EP15R_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.014127 (rank : 129)
Query Neighborhood Hits	169	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

KINH_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.016822 (rank : 119)
Query Neighborhood Hits	169	Target Neighborhood Hits	1082	Shared Neighborhood Hits	38
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MINT_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.024227 (rank : 84)
Query Neighborhood Hits	169	Target Neighborhood Hits	1291	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MMP9_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.004575 (rank : 166)
Query Neighborhood Hits	169	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

STK10_MOUSE
θ value	5.27518 (rank : 117)	NC score	0.004713 (rank : 165)
Query Neighborhood Hits	169	Target Neighborhood Hits	2132	Shared Neighborhood Hits	51
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TGIF2_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.008438 (rank : 152)
Query Neighborhood Hits	169	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZN2	Gene names	TGIF2
Domain Architecture
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

ULK1_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.004557 (rank : 167)
Query Neighborhood Hits	169	Target Neighborhood Hits	1214	Shared Neighborhood Hits	48
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZBT16_HUMAN
θ value	5.27518 (rank : 120)	NC score	-0.000516 (rank : 176)
Query Neighborhood Hits	169	Target Neighborhood Hits	1010	Shared Neighborhood Hits	21
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZIC5_HUMAN
θ value	5.27518 (rank : 121)	NC score	-0.001516 (rank : 177)
Query Neighborhood Hits	169	Target Neighborhood Hits	774	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

CP135_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.017626 (rank : 114)
Query Neighborhood Hits	169	Target Neighborhood Hits	1290	Shared Neighborhood Hits	43
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CUTL2_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.011476 (rank : 137)
Query Neighborhood Hits	169	Target Neighborhood Hits	906	Shared Neighborhood Hits	41
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EXOC1_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.019412 (rank : 105)
Query Neighborhood Hits	169	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

FLIP1_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.016401 (rank : 122)
Query Neighborhood Hits	169	Target Neighborhood Hits	1405	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FOXL1_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.002734 (rank : 174)
Query Neighborhood Hits	169	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

HSF1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.032439 (rank : 58)
Query Neighborhood Hits	169	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

K1210_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.020023 (rank : 100)
Query Neighborhood Hits	169	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

LAP4_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.002885 (rank : 173)
Query Neighborhood Hits	169	Target Neighborhood Hits	608	Shared Neighborhood Hits	15
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MYOD1_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.007667 (rank : 154)
Query Neighborhood Hits	169	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

NIN_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.019724 (rank : 102)
Query Neighborhood Hits	169	Target Neighborhood Hits	1416	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SC6A5_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.002587 (rank : 175)
Query Neighborhood Hits	169	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y345, O95288, Q9BX77	Gene names	SLC6A5, GLYT2
Domain Architecture
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

SETBP_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.016409 (rank : 121)
Query Neighborhood Hits	169	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SYN1_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.024659 (rank : 82)
Query Neighborhood Hits	169	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

WASP_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.023023 (rank : 88)
Query Neighborhood Hits	169	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

ZIM10_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.018246 (rank : 113)
Query Neighborhood Hits	169	Target Neighborhood Hits	577	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

AB1IP_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.012659 (rank : 135)
Query Neighborhood Hits	169	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ATF6B_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.011000 (rank : 139)
Query Neighborhood Hits	169	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

BAT2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.033181 (rank : 56)
Query Neighborhood Hits	169	Target Neighborhood Hits	931	Shared Neighborhood Hits	63
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.034741 (rank : 54)
Query Neighborhood Hits	169	Target Neighborhood Hits	947	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.032256 (rank : 59)
Query Neighborhood Hits	169	Target Neighborhood Hits	770	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CE290_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.027302 (rank : 75)
Query Neighborhood Hits	169	Target Neighborhood Hits	1553	Shared Neighborhood Hits	50
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CO1A1_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.008447 (rank : 151)
Query Neighborhood Hits	169	Target Neighborhood Hits	475	Shared Neighborhood Hits	25
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

DEN1A_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.015001 (rank : 125)
Query Neighborhood Hits	169	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EFS_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.019979 (rank : 101)
Query Neighborhood Hits	169	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EHMT2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.009268 (rank : 147)
Query Neighborhood Hits	169	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EMIL1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.009193 (rank : 148)
Query Neighborhood Hits	169	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EP400_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.016672 (rank : 120)
Query Neighborhood Hits	169	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GLE1_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.018296 (rank : 111)
Query Neighborhood Hits	169	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

HCFC1_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.010233 (rank : 143)
Query Neighborhood Hits	169	Target Neighborhood Hits	331	Shared Neighborhood Hits	22
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HERC2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.003552 (rank : 171)
Query Neighborhood Hits	169	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

IL4RA_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.029524 (rank : 65)
Query Neighborhood Hits	169	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

K1C10_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.008066 (rank : 153)
Query Neighborhood Hits	169	Target Neighborhood Hits	526	Shared Neighborhood Hits	27
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

KREM1_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.004784 (rank : 163)
Query Neighborhood Hits	169	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

MAP4_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.015911 (rank : 123)
Query Neighborhood Hits	169	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MAST4_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.007552 (rank : 155)
Query Neighborhood Hits	169	Target Neighborhood Hits	1804	Shared Neighborhood Hits	62
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MRCKB_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.010630 (rank : 142)
Query Neighborhood Hits	169	Target Neighborhood Hits	2180	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NUMBL_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.013360 (rank : 132)
Query Neighborhood Hits	169	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

PDC6I_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.029249 (rank : 69)
Query Neighborhood Hits	169	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

SC24B_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.010970 (rank : 141)
Query Neighborhood Hits	169	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SEZ6L_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.013993 (rank : 131)
Query Neighborhood Hits	169	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SF01_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.024096 (rank : 85)
Query Neighborhood Hits	169	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SPEG_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.006740 (rank : 156)
Query Neighborhood Hits	169	Target Neighborhood Hits	1762	Shared Neighborhood Hits	51
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNE2_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.017130 (rank : 117)
Query Neighborhood Hits	169	Target Neighborhood Hits	1323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TARA_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.031100 (rank : 61)
Query Neighborhood Hits	169	Target Neighborhood Hits	1626	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TF7L2_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.005370 (rank : 159)
Query Neighborhood Hits	169	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TITIN_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.009600 (rank : 145)
Query Neighborhood Hits	169	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TMF1_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.019445 (rank : 104)
Query Neighborhood Hits	169	Target Neighborhood Hits	987	Shared Neighborhood Hits	37
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

ZYX_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.010997 (rank : 140)
Query Neighborhood Hits	169	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AP2A1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.093760 (rank : 23)
Query Neighborhood Hits	169	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.091228 (rank : 25)
Query Neighborhood Hits	169	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.091001 (rank : 26)
Query Neighborhood Hits	169	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.092474 (rank : 24)
Query Neighborhood Hits	169	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP3D1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.081867 (rank : 28)
Query Neighborhood Hits	169	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.085778 (rank : 27)
Query Neighborhood Hits	169	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP4E1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.095177 (rank : 22)
Query Neighborhood Hits	169	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.095262 (rank : 21)
Query Neighborhood Hits	169	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

Hits sorted by NC score

GGA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	169	Target Neighborhood Hits	169	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
NC score	0.975245 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	169	Target Neighborhood Hits	128	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_MOUSE
NC score	0.952646 (rank : 3)	θ value	2.06847e-121 (rank : 4)
Query Neighborhood Hits	169	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA2_HUMAN
NC score	0.949589 (rank : 4)	θ value	3.4016e-132 (rank : 3)
Query Neighborhood Hits	169	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA3_HUMAN
NC score	0.943656 (rank : 5)	θ value	2.44908e-114 (rank : 6)
Query Neighborhood Hits	169	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
NC score	0.931614 (rank : 6)	θ value	1.29861e-115 (rank : 5)
Query Neighborhood Hits	169	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TOM1_MOUSE
NC score	0.687548 (rank : 7)	θ value	7.0802e-21 (rank : 7)
Query Neighborhood Hits	169	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
NC score	0.682721 (rank : 8)	θ value	1.2077e-20 (rank : 8)
Query Neighborhood Hits	169	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TM1L1_MOUSE
NC score	0.652311 (rank : 9)	θ value	1.16975e-15 (rank : 9)
Query Neighborhood Hits	169	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_HUMAN
NC score	0.639318 (rank : 10)	θ value	6.41864e-14 (rank : 11)
Query Neighborhood Hits	169	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

HGS_MOUSE
NC score	0.405825 (rank : 11)	θ value	1.02475e-11 (rank : 13)
Query Neighborhood Hits	169	Target Neighborhood Hits	589	Shared Neighborhood Hits	56
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
NC score	0.404895 (rank : 12)	θ value	1.74796e-11 (rank : 14)
Query Neighborhood Hits	169	Target Neighborhood Hits	517	Shared Neighborhood Hits	47
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STAM2_HUMAN
NC score	0.395639 (rank : 13)	θ value	3.64472e-09 (rank : 18)
Query Neighborhood Hits	169	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM1_HUMAN
NC score	0.389598 (rank : 14)	θ value	3.29651e-10 (rank : 16)
Query Neighborhood Hits	169	Target Neighborhood Hits	271	Shared Neighborhood Hits	22
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
NC score	0.384835 (rank : 15)	θ value	1.9326e-10 (rank : 15)
Query Neighborhood Hits	169	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.381041 (rank : 16)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	169	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

AP1G1_HUMAN
NC score	0.367836 (rank : 17)	θ value	1.29331e-14 (rank : 10)
Query Neighborhood Hits	169	Target Neighborhood Hits	65	Shared Neighborhood Hits	11
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
NC score	0.358548 (rank : 18)	θ value	3.52202e-12 (rank : 12)
Query Neighborhood Hits	169	Target Neighborhood Hits	67	Shared Neighborhood Hits	11
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_MOUSE
NC score	0.348564 (rank : 19)	θ value	5.62301e-10 (rank : 17)
Query Neighborhood Hits	169	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_HUMAN
NC score	0.339757 (rank : 20)	θ value	1.06045e-08 (rank : 20)
Query Neighborhood Hits	169	Target Neighborhood Hits	44	Shared Neighborhood Hits	10
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP4E1_MOUSE
NC score	0.095262 (rank : 21)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	169	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_HUMAN
NC score	0.095177 (rank : 22)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	169	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP2A1_HUMAN
NC score	0.093760 (rank : 23)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	169	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_MOUSE
NC score	0.092474 (rank : 24)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	169	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A1_MOUSE
NC score	0.091228 (rank : 25)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	169	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
NC score	0.091001 (rank : 26)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	169	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP3D1_MOUSE
NC score	0.085778 (rank : 27)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	169	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP3D1_HUMAN
NC score	0.081867 (rank : 28)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	169	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

STMN1_MOUSE
NC score	0.071891 (rank : 29)	θ value	0.00869519 (rank : 22)
Query Neighborhood Hits	169	Target Neighborhood Hits	560	Shared Neighborhood Hits	24
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

STMN1_HUMAN
NC score	0.071231 (rank : 30)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	169	Target Neighborhood Hits	554	Shared Neighborhood Hits	24
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

CJ012_HUMAN
NC score	0.071133 (rank : 31)	θ value	0.0113563 (rank : 23)
Query Neighborhood Hits	169	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

MLL3_MOUSE
NC score	0.059119 (rank : 32)	θ value	0.0148317 (rank : 24)
Query Neighborhood Hits	169	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.059046 (rank : 33)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	169	Target Neighborhood Hits	1644	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

T22D4_HUMAN
NC score	0.058063 (rank : 34)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	169	Target Neighborhood Hits	403	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

SET1A_HUMAN
NC score	0.047769 (rank : 35)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	169	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MBD6_HUMAN
NC score	0.045465 (rank : 36)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	169	Target Neighborhood Hits	349	Shared Neighborhood Hits	32
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MUC7_HUMAN
NC score	0.044829 (rank : 37)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	169	Target Neighborhood Hits	538	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

WASIP_MOUSE
NC score	0.044539 (rank : 38)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	169	Target Neighborhood Hits	392	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CNOT4_MOUSE
NC score	0.043855 (rank : 39)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	169	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RTN4_MOUSE
NC score	0.043702 (rank : 40)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	169	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

CIC_HUMAN
NC score	0.042719 (rank : 41)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	169	Target Neighborhood Hits	992	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

EPN1_HUMAN
NC score	0.040766 (rank : 42)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	169	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

HCLS1_MOUSE
NC score	0.040503 (rank : 43)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	169	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

ASPP2_HUMAN
NC score	0.040146 (rank : 44)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	169	Target Neighborhood Hits	1156	Shared Neighborhood Hits	59
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

NCOA6_MOUSE
NC score	0.038358 (rank : 45)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	169	Target Neighborhood Hits	1076	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

EPN1_MOUSE
NC score	0.038091 (rank : 46)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	169	Target Neighborhood Hits	240	Shared Neighborhood Hits	20
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

DACH1_MOUSE
NC score	0.038052 (rank : 47)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	169	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

SRRM2_HUMAN
NC score	0.037329 (rank : 48)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	169	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

LR37A_HUMAN
NC score	0.037123 (rank : 49)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	169	Target Neighborhood Hits	720	Shared Neighborhood Hits	42
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

WASL_MOUSE
NC score	0.037009 (rank : 50)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	169	Target Neighborhood Hits	339	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

RTP3_MOUSE
NC score	0.036468 (rank : 51)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	169	Target Neighborhood Hits	374	Shared Neighborhood Hits	36
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RTN4_HUMAN
NC score	0.035920 (rank : 52)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	169	Target Neighborhood Hits	357	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

ARMC4_HUMAN
NC score	0.035626 (rank : 53)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	169	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

BAT2_MOUSE
NC score	0.034741 (rank : 54)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	169	Target Neighborhood Hits	947	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SAPS1_HUMAN
NC score	0.034177 (rank : 55)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	169	Target Neighborhood Hits	704	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BAT2_HUMAN
NC score	0.033181 (rank : 56)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	169	Target Neighborhood Hits	931	Shared Neighborhood Hits	63
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SYCP1_MOUSE
NC score	0.032682 (rank : 57)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	169	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

HSF1_MOUSE
NC score	0.032439 (rank : 58)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	169	Target Neighborhood Hits	267	Shared Neighborhood Hits	26
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

BCL9_MOUSE
NC score	0.032256 (rank : 59)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	169	Target Neighborhood Hits	770	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

GPTC8_HUMAN
NC score	0.032077 (rank : 60)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	169	Target Neighborhood Hits	366	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TARA_HUMAN
NC score	0.031100 (rank : 61)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	169	Target Neighborhood Hits	1626	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AZI1_HUMAN
NC score	0.030323 (rank : 62)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	169	Target Neighborhood Hits	1000	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

FOSB_MOUSE
NC score	0.030097 (rank : 63)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	169	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

RGS3_HUMAN
NC score	0.029828 (rank : 64)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	169	Target Neighborhood Hits	1375	Shared Neighborhood Hits	78
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IL4RA_HUMAN
NC score	0.029524 (rank : 65)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	169	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

DMD_MOUSE
NC score	0.029454 (rank : 66)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	169	Target Neighborhood Hits	1111	Shared Neighborhood Hits	38
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

SF01_HUMAN
NC score	0.029405 (rank : 67)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	169	Target Neighborhood Hits	287	Shared Neighborhood Hits	25
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

DMD_HUMAN
NC score	0.029376 (rank : 68)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	169	Target Neighborhood Hits	1135	Shared Neighborhood Hits	38
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

PDC6I_MOUSE
NC score	0.029249 (rank : 69)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	169	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU78, O88695, O89014, Q8BSL8, Q8R0H5, Q99LR3, Q9QZN8	Gene names	Pdcd6ip, Aip1, Alix
Domain Architecture
Description	Programmed cell death 6-interacting protein (ALG-2-interacting protein X) (ALG-2-interacting protein 1) (E2F1-inducible protein) (Eig2).

BTBDC_HUMAN
NC score	0.029143 (rank : 70)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	169	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

RD23B_MOUSE
NC score	0.028950 (rank : 71)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	169	Target Neighborhood Hits	189	Shared Neighborhood Hits	9
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

NSD1_HUMAN
NC score	0.028820 (rank : 72)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	169	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

K1958_HUMAN
NC score	0.028132 (rank : 73)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	169	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

BAT3_HUMAN
NC score	0.027678 (rank : 74)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	169	Target Neighborhood Hits	490	Shared Neighborhood Hits	38
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CE290_HUMAN
NC score	0.027302 (rank : 75)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	169	Target Neighborhood Hits	1553	Shared Neighborhood Hits	50
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TACC2_MOUSE
NC score	0.026362 (rank : 76)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	169	Target Neighborhood Hits	774	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

LRC45_HUMAN
NC score	0.026286 (rank : 77)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	169	Target Neighborhood Hits	933	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

DIAP1_HUMAN
NC score	0.025881 (rank : 78)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	169	Target Neighborhood Hits	784	Shared Neighborhood Hits	40
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

PF21B_MOUSE
NC score	0.025184 (rank : 79)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	169	Target Neighborhood Hits	278	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SYGP1_HUMAN
NC score	0.024841 (rank : 80)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	169	Target Neighborhood Hits	589	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SMCA4_HUMAN
NC score	0.024797 (rank : 81)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	169	Target Neighborhood Hits	597	Shared Neighborhood Hits	40
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SYN1_HUMAN
NC score	0.024659 (rank : 82)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	169	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SHAN1_HUMAN
NC score	0.024638 (rank : 83)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	169	Target Neighborhood Hits	1041	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MINT_HUMAN
NC score	0.024227 (rank : 84)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	169	Target Neighborhood Hits	1291	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SF01_MOUSE
NC score	0.024096 (rank : 85)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	169	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SOCS7_MOUSE
NC score	0.024074 (rank : 86)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	169	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

UTRO_HUMAN
NC score	0.023260 (rank : 87)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	169	Target Neighborhood Hits	960	Shared Neighborhood Hits	35
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

WASP_HUMAN
NC score	0.023023 (rank : 88)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	169	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P42768, Q9BU11, Q9UNJ9	Gene names	WAS, IMD2
Domain Architecture
Description	Wiskott-Aldrich syndrome protein (WASp).

IF39_HUMAN
NC score	0.022803 (rank : 89)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	169	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

HNRL1_HUMAN
NC score	0.022652 (rank : 90)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	169	Target Neighborhood Hits	173	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

CASL_MOUSE
NC score	0.022615 (rank : 91)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	169	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

DCC_MOUSE
NC score	0.022582 (rank : 92)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	169	Target Neighborhood Hits	896	Shared Neighborhood Hits	49
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

COEA1_MOUSE
NC score	0.022582 (rank : 93)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	169	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

PTN23_HUMAN
NC score	0.021678 (rank : 94)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	169	Target Neighborhood Hits	646	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SYN2_HUMAN
NC score	0.021331 (rank : 95)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	169	Target Neighborhood Hits	213	Shared Neighborhood Hits	22
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

COEA1_HUMAN
NC score	0.021144 (rank : 96)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	169	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CENPE_HUMAN
NC score	0.020220 (rank : 97)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	169	Target Neighborhood Hits	2060	Shared Neighborhood Hits	54
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

WASF2_MOUSE
NC score	0.020179 (rank : 98)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	169	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

SYNJ1_HUMAN
NC score	0.020157 (rank : 99)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	169	Target Neighborhood Hits	498	Shared Neighborhood Hits	39
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

K1210_HUMAN
NC score	0.020023 (rank : 100)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	169	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

EFS_HUMAN
NC score	0.019979 (rank : 101)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	169	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

NIN_HUMAN
NC score	0.019724 (rank : 102)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	169	Target Neighborhood Hits	1416	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

ANGL5_HUMAN
NC score	0.019486 (rank : 103)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	169	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

TMF1_HUMAN
NC score	0.019445 (rank : 104)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	169	Target Neighborhood Hits	987	Shared Neighborhood Hits	37
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

EXOC1_HUMAN
NC score	0.019412 (rank : 105)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	169	Target Neighborhood Hits	183	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NV70, Q8WUE7, Q96T15, Q9NZE4	Gene names	EXOC1, SEC3, SEC3L1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 1 (Exocyst complex component Sec3).

KINH_HUMAN
NC score	0.018751 (rank : 106)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	169	Target Neighborhood Hits	1231	Shared Neighborhood Hits	40
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

BORG5_HUMAN
NC score	0.018440 (rank : 107)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	169	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

YTHD1_HUMAN
NC score	0.018413 (rank : 108)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	169	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYJ9, Q8N3G5, Q8TBT1, Q96AN4, Q96S57, Q9BTI7, Q9NX79	Gene names	YTHDF1, C20orf21
Domain Architecture
Description	YTH domain family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1).

NCOR1_HUMAN
NC score	0.018305 (rank : 109)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	169	Target Neighborhood Hits	577	Shared Neighborhood Hits	32
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

BPAEA_MOUSE
NC score	0.018304 (rank : 110)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	169	Target Neighborhood Hits	1480	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GLE1_MOUSE
NC score	0.018296 (rank : 111)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	169	Target Neighborhood Hits	504	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

CO4A5_HUMAN
NC score	0.018253 (rank : 112)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	169	Target Neighborhood Hits	383	Shared Neighborhood Hits	23
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

ZIM10_HUMAN
NC score	0.018246 (rank : 113)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	169	Target Neighborhood Hits	577	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CP135_HUMAN
NC score	0.017626 (rank : 114)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	169	Target Neighborhood Hits	1290	Shared Neighborhood Hits	43
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SYP2L_HUMAN
NC score	0.017437 (rank : 115)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	169	Target Neighborhood Hits	400	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

ROCK1_HUMAN
NC score	0.017320 (rank : 116)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	169	Target Neighborhood Hits	2000	Shared Neighborhood Hits	49
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SYNE2_HUMAN
NC score	0.017130 (rank : 117)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	169	Target Neighborhood Hits	1323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TENS1_HUMAN
NC score	0.016937 (rank : 118)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	169	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

KINH_MOUSE
NC score	0.016822 (rank : 119)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	169	Target Neighborhood Hits	1082	Shared Neighborhood Hits	38
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

EP400_HUMAN
NC score	0.016672 (rank : 120)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	169	Target Neighborhood Hits	556	Shared Neighborhood Hits	34
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

SETBP_MOUSE
NC score	0.016409 (rank : 121)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	169	Target Neighborhood Hits	352	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

FLIP1_HUMAN
NC score	0.016401 (rank : 122)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	169	Target Neighborhood Hits	1405	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MAP4_HUMAN
NC score	0.015911 (rank : 123)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	169	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ROCK1_MOUSE
NC score	0.015290 (rank : 124)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	169	Target Neighborhood Hits	2126	Shared Neighborhood Hits	51
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

DEN1A_HUMAN
NC score	0.015001 (rank : 125)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	169	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

PTPRD_HUMAN
NC score	0.014909 (rank : 126)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	169	Target Neighborhood Hits	485	Shared Neighborhood Hits	12
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

ASXL1_HUMAN
NC score	0.014512 (rank : 127)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	169	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TM16H_HUMAN
NC score	0.014390 (rank : 128)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	169	Target Neighborhood Hits	139	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

EP15R_MOUSE
NC score	0.014127 (rank : 129)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	169	Target Neighborhood Hits	1135	Shared Neighborhood Hits	42
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

PTPRD_MOUSE
NC score	0.014121 (rank : 130)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	169	Target Neighborhood Hits	491	Shared Neighborhood Hits	13
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SEZ6L_HUMAN
NC score	0.013993 (rank : 131)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	169	Target Neighborhood Hits	289	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

NUMBL_MOUSE
NC score	0.013360 (rank : 132)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	169	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	O08919, Q6NVG8	Gene names	Numbl, Nbl
Domain Architecture
Description	Numb-like protein.

MGRN1_MOUSE
NC score	0.012897 (rank : 133)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	169	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

ELL2_HUMAN
NC score	0.012700 (rank : 134)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	169	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	O00472	Gene names	ELL2
Domain Architecture
Description	RNA polymerase II elongation factor ELL2.

AB1IP_HUMAN
NC score	0.012659 (rank : 135)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	169	Target Neighborhood Hits	213	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

MRCKA_HUMAN
NC score	0.012068 (rank : 136)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	169	Target Neighborhood Hits	1999	Shared Neighborhood Hits	47
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

CUTL2_HUMAN
NC score	0.011476 (rank : 137)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	169	Target Neighborhood Hits	906	Shared Neighborhood Hits	41
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CO9A3_HUMAN
NC score	0.011215 (rank : 138)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	169	Target Neighborhood Hits	361	Shared Neighborhood Hits	15
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

ATF6B_HUMAN
NC score	0.011000 (rank : 139)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	169	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	Q99941, Q13269, Q14343, Q14345, Q99635, Q99637, Q9H3V9, Q9H3W1, Q9NPL0	Gene names	CREBL1, G13
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp) (Protein G13).

ZYX_HUMAN
NC score	0.010997 (rank : 140)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	169	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

SC24B_HUMAN
NC score	0.010970 (rank : 141)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	169	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

MRCKB_MOUSE
NC score	0.010630 (rank : 142)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	169	Target Neighborhood Hits	2180	Shared Neighborhood Hits	55
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

HCFC1_HUMAN
NC score	0.010233 (rank : 143)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	169	Target Neighborhood Hits	331	Shared Neighborhood Hits	22
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MAGI2_HUMAN
NC score	0.009654 (rank : 144)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	169	Target Neighborhood Hits	373	Shared Neighborhood Hits	23
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

TITIN_HUMAN
NC score	0.009600 (rank : 145)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	169	Target Neighborhood Hits	2923	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FOXP4_MOUSE
NC score	0.009325 (rank : 146)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	169	Target Neighborhood Hits	211	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

EHMT2_HUMAN
NC score	0.009268 (rank : 147)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	169	Target Neighborhood Hits	498	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EMIL1_MOUSE
NC score	0.009193 (rank : 148)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	169	Target Neighborhood Hits	214	Shared Neighborhood Hits	19
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

KRHB5_HUMAN
NC score	0.008935 (rank : 149)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	169	Target Neighborhood Hits	321	Shared Neighborhood Hits	13
SwissProt Accessions	P78386, Q9NSB1	Gene names	KRTHB5
Domain Architecture
Description	Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5).

OBSCN_HUMAN
NC score	0.008705 (rank : 150)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	169	Target Neighborhood Hits	1931	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CO1A1_HUMAN
NC score	0.008447 (rank : 151)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	169	Target Neighborhood Hits	475	Shared Neighborhood Hits	25
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

TGIF2_HUMAN
NC score	0.008438 (rank : 152)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	169	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZN2	Gene names	TGIF2
Domain Architecture
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

K1C10_HUMAN
NC score	0.008066 (rank : 153)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	169	Target Neighborhood Hits	526	Shared Neighborhood Hits	27
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

MYOD1_MOUSE
NC score	0.007667 (rank : 154)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	169	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MAST4_HUMAN
NC score	0.007552 (rank : 155)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	169	Target Neighborhood Hits	1804	Shared Neighborhood Hits	62
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SPEG_HUMAN
NC score	0.006740 (rank : 156)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	169	Target Neighborhood Hits	1762	Shared Neighborhood Hits	51
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

LIRB5_HUMAN
NC score	0.006374 (rank : 157)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	169	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	O75023, Q8N760	Gene names	LILRB5, LIR8
Domain Architecture
Description	Leukocyte immunoglobulin-like receptor subfamily B member 5 precursor (Leukocyte immunoglobulin-like receptor 8) (LIR-8) (CD85c antigen).

ATBF1_HUMAN
NC score	0.006054 (rank : 158)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	169	Target Neighborhood Hits	1547	Shared Neighborhood Hits	41
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TF7L2_HUMAN
NC score	0.005370 (rank : 159)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	169	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

PHLPP_MOUSE
NC score	0.005124 (rank : 160)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	169	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

NMDE4_HUMAN
NC score	0.005073 (rank : 161)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	169	Target Neighborhood Hits	133	Shared Neighborhood Hits	5
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

SALL3_HUMAN
NC score	0.005033 (rank : 162)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	169	Target Neighborhood Hits	1066	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

KREM1_MOUSE
NC score	0.004784 (rank : 163)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	169	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

DDX21_MOUSE
NC score	0.004767 (rank : 164)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	169	Target Neighborhood Hits	350	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

STK10_MOUSE
NC score	0.004713 (rank : 165)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	169	Target Neighborhood Hits	2132	Shared Neighborhood Hits	51
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MMP9_MOUSE
NC score	0.004575 (rank : 166)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	169	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

ULK1_MOUSE
NC score	0.004557 (rank : 167)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	169	Target Neighborhood Hits	1214	Shared Neighborhood Hits	48
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ZBTB3_HUMAN
NC score	0.004359 (rank : 168)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	169	Target Neighborhood Hits	910	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

BRSK2_HUMAN
NC score	0.003907 (rank : 169)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	169	Target Neighborhood Hits	897	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWQ3, O60843, O95099, Q5J5B4, Q8TB60	Gene names	BRSK2, C11orf7, PEN11B, STK29
Domain Architecture
Description	BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine- protein kinase 29) (SAD1B).

WEE1_HUMAN
NC score	0.003873 (rank : 170)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	169	Target Neighborhood Hits	777	Shared Neighborhood Hits	14
SwissProt Accessions	P30291	Gene names	WEE1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu).

HERC2_MOUSE
NC score	0.003552 (rank : 171)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	169	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q4U2R1, O88473, Q3TRJ8, Q3TS47, Q3TST2, Q3UFQ6, Q3URH7, Q5DU32, Q7TPR5, Q80VV7, Q9QYT1, Q9Z168, Q9Z171	Gene names	Herc2, jdf2, Kiaa0393, rjs
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

ZBTB4_HUMAN
NC score	0.003243 (rank : 172)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	169	Target Neighborhood Hits	926	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

LAP4_HUMAN
NC score	0.002885 (rank : 173)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	169	Target Neighborhood Hits	608	Shared Neighborhood Hits	15
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

FOXL1_HUMAN
NC score	0.002734 (rank : 174)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	169	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

SC6A5_HUMAN
NC score	0.002587 (rank : 175)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	169	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y345, O95288, Q9BX77	Gene names	SLC6A5, GLYT2
Domain Architecture
Description	Sodium- and chloride-dependent glycine transporter 2 (GlyT2) (GlyT-2) (Solute carrier family 6 member 5).

ZBT16_HUMAN
NC score	-0.000516 (rank : 176)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	169	Target Neighborhood Hits	1010	Shared Neighborhood Hits	21
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZIC5_HUMAN
NC score	-0.001516 (rank : 177)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	169	Target Neighborhood Hits	774	Shared Neighborhood Hits	18
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).