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Network neighborhood for query Sequence : HSF1_MOUSE

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HSF1_MOUSE
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HSF1_HUMAN
θ value	0 (rank : 1)	NC score	0.942551 (rank : 2)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	85
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	267
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF2_HUMAN
θ value	4.22625e-74 (rank : 3)	NC score	0.834253 (rank : 6)
Query Neighborhood Hits	267	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_MOUSE
θ value	2.73936e-73 (rank : 4)	NC score	0.834754 (rank : 5)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF4_HUMAN
θ value	8.81223e-72 (rank : 5)	NC score	0.857980 (rank : 3)
Query Neighborhood Hits	267	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

HSF4_MOUSE
θ value	4.83544e-70 (rank : 6)	NC score	0.857710 (rank : 4)
Query Neighborhood Hits	267	Target Neighborhood Hits	57	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

HSFY1_HUMAN
θ value	1.53129e-07 (rank : 7)	NC score	0.495755 (rank : 7)
Query Neighborhood Hits	267	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q96LI6, Q7Z4L8, Q9BZA2, Q9BZA3	Gene names	HSFY1, HSF2L, HSFY
Domain Architecture
Description	Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like).

CJ078_MOUSE
θ value	0.000121331 (rank : 8)	NC score	0.122567 (rank : 9)
Query Neighborhood Hits	267	Target Neighborhood Hits	559	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

KLF13_MOUSE
θ value	0.000461057 (rank : 9)	NC score	0.018040 (rank : 240)
Query Neighborhood Hits	267	Target Neighborhood Hits	757	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

CSKI1_HUMAN
θ value	0.00102713 (rank : 10)	NC score	0.058617 (rank : 72)
Query Neighborhood Hits	267	Target Neighborhood Hits	997	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GGA3_MOUSE
θ value	0.00134147 (rank : 11)	NC score	0.055044 (rank : 87)
Query Neighborhood Hits	267	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

MLL2_HUMAN
θ value	0.00390308 (rank : 12)	NC score	0.092469 (rank : 19)
Query Neighborhood Hits	267	Target Neighborhood Hits	1788	Shared Neighborhood Hits	134
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CEND3_MOUSE
θ value	0.00509761 (rank : 13)	NC score	0.067230 (rank : 44)
Query Neighborhood Hits	267	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CSKI1_MOUSE
θ value	0.00665767 (rank : 14)	NC score	0.064699 (rank : 53)
Query Neighborhood Hits	267	Target Neighborhood Hits	1031	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MORC2_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.055384 (rank : 84)
Query Neighborhood Hits	267	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

PCQAP_HUMAN
θ value	0.0113563 (rank : 16)	NC score	0.103015 (rank : 12)
Query Neighborhood Hits	267	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

TLE4_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.053497 (rank : 92)
Query Neighborhood Hits	267	Target Neighborhood Hits	477	Shared Neighborhood Hits	43
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

MUC2_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.058107 (rank : 76)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	64
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.076713 (rank : 33)
Query Neighborhood Hits	267	Target Neighborhood Hits	538	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TLE4_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.053608 (rank : 91)
Query Neighborhood Hits	267	Target Neighborhood Hits	482	Shared Neighborhood Hits	43
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

PCQAP_MOUSE
θ value	0.0193708 (rank : 21)	NC score	0.095801 (rank : 17)
Query Neighborhood Hits	267	Target Neighborhood Hits	506	Shared Neighborhood Hits	43
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

BCL9_MOUSE
θ value	0.0252991 (rank : 22)	NC score	0.097352 (rank : 15)
Query Neighborhood Hits	267	Target Neighborhood Hits	770	Shared Neighborhood Hits	104
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

JPH2_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.061570 (rank : 61)
Query Neighborhood Hits	267	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ZAN_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.050143 (rank : 106)
Query Neighborhood Hits	267	Target Neighborhood Hits	679	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SPEG_HUMAN
θ value	0.0330416 (rank : 25)	NC score	0.019945 (rank : 232)
Query Neighborhood Hits	267	Target Neighborhood Hits	1762	Shared Neighborhood Hits	88
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BSN_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.072535 (rank : 34)
Query Neighborhood Hits	267	Target Neighborhood Hits	1537	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MLL3_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.103802 (rank : 11)
Query Neighborhood Hits	267	Target Neighborhood Hits	1399	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZN692_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.010949 (rank : 274)
Query Neighborhood Hits	267	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

P53_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.053314 (rank : 93)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

ENAH_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.062899 (rank : 55)
Query Neighborhood Hits	267	Target Neighborhood Hits	919	Shared Neighborhood Hits	77
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

JPH2_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.064977 (rank : 52)
Query Neighborhood Hits	267	Target Neighborhood Hits	639	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MAML1_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.060340 (rank : 65)
Query Neighborhood Hits	267	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SETD2_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.066677 (rank : 47)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

WASF1_HUMAN
θ value	0.0736092 (rank : 34)	NC score	0.066116 (rank : 49)
Query Neighborhood Hits	267	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

ANK2_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.054036 (rank : 90)
Query Neighborhood Hits	267	Target Neighborhood Hits	1615	Shared Neighborhood Hits	135
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

WASF1_MOUSE
θ value	0.0961366 (rank : 36)	NC score	0.065138 (rank : 51)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

MINK1_HUMAN
θ value	0.125558 (rank : 37)	NC score	0.016486 (rank : 247)
Query Neighborhood Hits	267	Target Neighborhood Hits	1477	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

RTN4_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.056841 (rank : 79)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SEM6B_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.022973 (rank : 211)
Query Neighborhood Hits	267	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

TRIPB_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.040640 (rank : 134)
Query Neighborhood Hits	267	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GLI2_HUMAN
θ value	0.163984 (rank : 41)	NC score	0.014006 (rank : 263)
Query Neighborhood Hits	267	Target Neighborhood Hits	971	Shared Neighborhood Hits	49
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

RCOR3_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.042264 (rank : 129)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

CEND3_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.056924 (rank : 78)
Query Neighborhood Hits	267	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

HIC1_MOUSE
θ value	0.21417 (rank : 44)	NC score	0.007976 (rank : 290)
Query Neighborhood Hits	267	Target Neighborhood Hits	863	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

UBE4B_HUMAN
θ value	0.21417 (rank : 45)	NC score	0.058931 (rank : 71)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

MY18B_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.041233 (rank : 131)
Query Neighborhood Hits	267	Target Neighborhood Hits	1299	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYO5A_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.023730 (rank : 207)
Query Neighborhood Hits	267	Target Neighborhood Hits	1117	Shared Neighborhood Hits	41
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

PHC3_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.034342 (rank : 164)
Query Neighborhood Hits	267	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PRDM2_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.029082 (rank : 186)
Query Neighborhood Hits	267	Target Neighborhood Hits	1135	Shared Neighborhood Hits	58
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SDC3_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.055332 (rank : 85)
Query Neighborhood Hits	267	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SMOO_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.052975 (rank : 96)
Query Neighborhood Hits	267	Target Neighborhood Hits	391	Shared Neighborhood Hits	42
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

WASIP_MOUSE
θ value	0.279714 (rank : 52)	NC score	0.077681 (rank : 32)
Query Neighborhood Hits	267	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ARHGF_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.031517 (rank : 176)
Query Neighborhood Hits	267	Target Neighborhood Hits	214	Shared Neighborhood Hits	25
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

CENG1_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.036307 (rank : 152)
Query Neighborhood Hits	267	Target Neighborhood Hits	531	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

JHD3B_MOUSE
θ value	0.365318 (rank : 55)	NC score	0.028790 (rank : 187)
Query Neighborhood Hits	267	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KCNH2_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.037579 (rank : 146)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0.365318 (rank : 57)	NC score	0.028412 (rank : 188)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

MKL1_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.043480 (rank : 121)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

PRG4_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.047829 (rank : 112)
Query Neighborhood Hits	267	Target Neighborhood Hits	764	Shared Neighborhood Hits	63
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TOM40_MOUSE
θ value	0.365318 (rank : 60)	NC score	0.032773 (rank : 171)
Query Neighborhood Hits	267	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYA2, Q9Z2N1	Gene names	Tomm40, Mom35, Tom40
Domain Architecture
Description	Probable mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog).

BAP29_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.079968 (rank : 28)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	24
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

CBP_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.069275 (rank : 38)
Query Neighborhood Hits	267	Target Neighborhood Hits	941	Shared Neighborhood Hits	97
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GSCR1_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.070119 (rank : 37)
Query Neighborhood Hits	267	Target Neighborhood Hits	674	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCN2_MOUSE
θ value	0.47712 (rank : 64)	NC score	0.037924 (rank : 143)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	46
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

HXA3_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.020134 (rank : 229)
Query Neighborhood Hits	267	Target Neighborhood Hits	558	Shared Neighborhood Hits	41
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MAST1_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.011750 (rank : 272)
Query Neighborhood Hits	267	Target Neighborhood Hits	1146	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MGR1_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.013453 (rank : 265)
Query Neighborhood Hits	267	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

NACAM_MOUSE
θ value	0.47712 (rank : 68)	NC score	0.132552 (rank : 8)
Query Neighborhood Hits	267	Target Neighborhood Hits	1866	Shared Neighborhood Hits	180
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOTC3_HUMAN
θ value	0.47712 (rank : 69)	NC score	0.015279 (rank : 252)
Query Neighborhood Hits	267	Target Neighborhood Hits	1062	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SGIP1_HUMAN
θ value	0.47712 (rank : 70)	NC score	0.062726 (rank : 57)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNP2_MOUSE
θ value	0.47712 (rank : 71)	NC score	0.054674 (rank : 88)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

APXL_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.052005 (rank : 98)
Query Neighborhood Hits	267	Target Neighborhood Hits	553	Shared Neighborhood Hits	56
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BAT2_HUMAN
θ value	0.62314 (rank : 73)	NC score	0.068925 (rank : 39)
Query Neighborhood Hits	267	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.102952 (rank : 13)
Query Neighborhood Hits	267	Target Neighborhood Hits	1008	Shared Neighborhood Hits	126
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CBP_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.078703 (rank : 30)
Query Neighborhood Hits	267	Target Neighborhood Hits	1051	Shared Neighborhood Hits	119
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

E2F4_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.036239 (rank : 153)
Query Neighborhood Hits	267	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

MEGF9_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.047242 (rank : 113)
Query Neighborhood Hits	267	Target Neighborhood Hits	896	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PDZD2_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.048747 (rank : 110)
Query Neighborhood Hits	267	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CDT1_MOUSE
θ value	0.813845 (rank : 79)	NC score	0.037543 (rank : 147)
Query Neighborhood Hits	267	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

CUTL2_MOUSE
θ value	0.813845 (rank : 80)	NC score	0.035296 (rank : 157)
Query Neighborhood Hits	267	Target Neighborhood Hits	771	Shared Neighborhood Hits	50
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EEA1_MOUSE
θ value	0.813845 (rank : 81)	NC score	0.030960 (rank : 177)
Query Neighborhood Hits	267	Target Neighborhood Hits	1637	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

KI21A_HUMAN
θ value	0.813845 (rank : 82)	NC score	0.025503 (rank : 199)
Query Neighborhood Hits	267	Target Neighborhood Hits	1543	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KI21A_MOUSE
θ value	0.813845 (rank : 83)	NC score	0.023989 (rank : 206)
Query Neighborhood Hits	267	Target Neighborhood Hits	1317	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

M3K6_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.009142 (rank : 285)
Query Neighborhood Hits	267	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MAP9_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.032181 (rank : 174)
Query Neighborhood Hits	267	Target Neighborhood Hits	529	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RP1L1_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.043161 (rank : 123)
Query Neighborhood Hits	267	Target Neighborhood Hits	1072	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TRI66_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.043063 (rank : 125)
Query Neighborhood Hits	267	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WHRN_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.029775 (rank : 183)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

AP180_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.033678 (rank : 169)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

CIC_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.061119 (rank : 63)
Query Neighborhood Hits	267	Target Neighborhood Hits	992	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CXXC6_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.059413 (rank : 69)
Query Neighborhood Hits	267	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

EEA1_HUMAN
θ value	1.06291 (rank : 92)	NC score	0.027482 (rank : 190)
Query Neighborhood Hits	267	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ETV3_HUMAN
θ value	1.06291 (rank : 93)	NC score	0.035416 (rank : 156)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GAK_MOUSE
θ value	1.06291 (rank : 94)	NC score	0.011772 (rank : 271)
Query Neighborhood Hits	267	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

IRS2_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.050669 (rank : 105)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MEGF9_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.021192 (rank : 223)
Query Neighborhood Hits	267	Target Neighborhood Hits	557	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MNT_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.048990 (rank : 109)
Query Neighborhood Hits	267	Target Neighborhood Hits	432	Shared Neighborhood Hits	52
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

POGZ_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.010904 (rank : 275)
Query Neighborhood Hits	267	Target Neighborhood Hits	745	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RBP2_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.022824 (rank : 213)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RIMB1_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.039505 (rank : 137)
Query Neighborhood Hits	267	Target Neighborhood Hits	1479	Shared Neighborhood Hits	101
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

2A5G_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.021074 (rank : 225)
Query Neighborhood Hits	267	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q13362, Q14391, Q15060, Q15174	Gene names	PPP2R5C, KIAA0044
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (NY-REN-29 antigen).

AFF1_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.035021 (rank : 159)
Query Neighborhood Hits	267	Target Neighborhood Hits	506	Shared Neighborhood Hits	48
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AUTS2_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.038100 (rank : 142)
Query Neighborhood Hits	267	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAP31_MOUSE
θ value	1.38821 (rank : 104)	NC score	0.067624 (rank : 43)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

BCL6_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.007107 (rank : 293)
Query Neighborhood Hits	267	Target Neighborhood Hits	913	Shared Neighborhood Hits	45
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BRD4_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.035255 (rank : 158)
Query Neighborhood Hits	267	Target Neighborhood Hits	851	Shared Neighborhood Hits	71
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CD2L7_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.010192 (rank : 278)
Query Neighborhood Hits	267	Target Neighborhood Hits	1275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

IL3B2_MOUSE
θ value	1.38821 (rank : 108)	NC score	0.049495 (rank : 108)
Query Neighborhood Hits	267	Target Neighborhood Hits	372	Shared Neighborhood Hits	55
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

MAML3_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.057367 (rank : 77)
Query Neighborhood Hits	267	Target Neighborhood Hits	323	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MOR2A_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.044550 (rank : 119)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

NIN_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.034735 (rank : 162)
Query Neighborhood Hits	267	Target Neighborhood Hits	1416	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

OPN4_HUMAN
θ value	1.38821 (rank : 112)	NC score	-0.001718 (rank : 304)
Query Neighborhood Hits	267	Target Neighborhood Hits	923	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHM6, Q2PP22, Q8NGQ9	Gene names	OPN4, MOP
Domain Architecture
Description	Melanopsin (Opsin-4).

PER1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.025204 (rank : 200)
Query Neighborhood Hits	267	Target Neighborhood Hits	215	Shared Neighborhood Hits	23
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

SDC3_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.051123 (rank : 104)
Query Neighborhood Hits	267	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

SRGP2_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.024185 (rank : 204)
Query Neighborhood Hits	267	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TIRAP_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.038643 (rank : 139)
Query Neighborhood Hits	267	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P58753, Q8N5E5	Gene names	TIRAP, MAL
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

WASIP_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.080525 (rank : 27)
Query Neighborhood Hits	267	Target Neighborhood Hits	458	Shared Neighborhood Hits	51
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WNK2_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.022842 (rank : 212)
Query Neighborhood Hits	267	Target Neighborhood Hits	1407	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

3BP1_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.037752 (rank : 145)
Query Neighborhood Hits	267	Target Neighborhood Hits	376	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AKAP1_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.022492 (rank : 215)
Query Neighborhood Hits	267	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

BAP31_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.061179 (rank : 62)
Query Neighborhood Hits	267	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

CENG1_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.032376 (rank : 173)
Query Neighborhood Hits	267	Target Neighborhood Hits	544	Shared Neighborhood Hits	28
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CORO7_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.015219 (rank : 253)
Query Neighborhood Hits	267	Target Neighborhood Hits	315	Shared Neighborhood Hits	12
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

DLGP4_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.017652 (rank : 243)
Query Neighborhood Hits	267	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

FMN1A_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.040831 (rank : 133)
Query Neighborhood Hits	267	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.039342 (rank : 138)
Query Neighborhood Hits	267	Target Neighborhood Hits	447	Shared Neighborhood Hits	50
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

MADCA_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.036547 (rank : 151)
Query Neighborhood Hits	267	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MINK1_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.014377 (rank : 259)
Query Neighborhood Hits	267	Target Neighborhood Hits	1451	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MLL4_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.058411 (rank : 73)
Query Neighborhood Hits	267	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NF2L2_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.033726 (rank : 168)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

PCD16_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.006860 (rank : 295)
Query Neighborhood Hits	267	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PTN23_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.030170 (rank : 181)
Query Neighborhood Hits	267	Target Neighborhood Hits	646	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RBP2_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.019959 (rank : 231)
Query Neighborhood Hits	267	Target Neighborhood Hits	249	Shared Neighborhood Hits	22
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RD23B_MOUSE
θ value	1.81305 (rank : 134)	NC score	0.025694 (rank : 197)
Query Neighborhood Hits	267	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

TNIK_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.015205 (rank : 254)
Query Neighborhood Hits	267	Target Neighborhood Hits	1570	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TTP_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.024084 (rank : 205)
Query Neighborhood Hits	267	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

VGF_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.037419 (rank : 148)
Query Neighborhood Hits	267	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

WNK4_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.019740 (rank : 234)
Query Neighborhood Hits	267	Target Neighborhood Hits	1043	Shared Neighborhood Hits	51
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

2A5G_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.019756 (rank : 233)
Query Neighborhood Hits	267	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q60996, O35708, Q99KW8, Q99N67, Q99N68	Gene names	Ppp2r5c
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B subunit, B'alpha3 isoform).

ATN1_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.051934 (rank : 99)
Query Neighborhood Hits	267	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BARH2_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.014305 (rank : 260)
Query Neighborhood Hits	267	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

CG1_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.056570 (rank : 80)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

CSKI2_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.042882 (rank : 127)
Query Neighborhood Hits	267	Target Neighborhood Hits	812	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT2NL_MOUSE
θ value	2.36792 (rank : 144)	NC score	0.030673 (rank : 180)
Query Neighborhood Hits	267	Target Neighborhood Hits	902	Shared Neighborhood Hits	50
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

EPN1_MOUSE
θ value	2.36792 (rank : 145)	NC score	0.022301 (rank : 217)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

ETV3_MOUSE
θ value	2.36792 (rank : 146)	NC score	0.021310 (rank : 222)
Query Neighborhood Hits	267	Target Neighborhood Hits	128	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

HMMR_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.031598 (rank : 175)
Query Neighborhood Hits	267	Target Neighborhood Hits	1082	Shared Neighborhood Hits	43
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HXA3_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.016036 (rank : 248)
Query Neighborhood Hits	267	Target Neighborhood Hits	535	Shared Neighborhood Hits	33
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXB2_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.010371 (rank : 277)
Query Neighborhood Hits	267	Target Neighborhood Hits	367	Shared Neighborhood Hits	17
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

IF4G1_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.026937 (rank : 193)
Query Neighborhood Hits	267	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

JHD3B_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.024604 (rank : 203)
Query Neighborhood Hits	267	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

MLL3_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.108437 (rank : 10)
Query Neighborhood Hits	267	Target Neighborhood Hits	1644	Shared Neighborhood Hits	152
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PRGC2_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.042888 (rank : 126)
Query Neighborhood Hits	267	Target Neighborhood Hits	272	Shared Neighborhood Hits	33
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

RAPH1_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.046045 (rank : 115)
Query Neighborhood Hits	267	Target Neighborhood Hits	593	Shared Neighborhood Hits	71
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RCOR3_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.029719 (rank : 184)
Query Neighborhood Hits	267	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SAM68_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.018294 (rank : 238)
Query Neighborhood Hits	267	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TAF4_HUMAN
θ value	2.36792 (rank : 157)	NC score	0.071193 (rank : 36)
Query Neighborhood Hits	267	Target Neighborhood Hits	687	Shared Neighborhood Hits	70
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

UACA_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.038135 (rank : 141)
Query Neighborhood Hits	267	Target Neighborhood Hits	1622	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UVRAG_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.043114 (rank : 124)
Query Neighborhood Hits	267	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

WIRE_MOUSE
θ value	2.36792 (rank : 160)	NC score	0.061953 (rank : 59)
Query Neighborhood Hits	267	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

WNK4_MOUSE
θ value	2.36792 (rank : 161)	NC score	0.015864 (rank : 249)
Query Neighborhood Hits	267	Target Neighborhood Hits	961	Shared Neighborhood Hits	47
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ABI2_HUMAN
θ value	3.0926 (rank : 162)	NC score	0.021527 (rank : 221)
Query Neighborhood Hits	267	Target Neighborhood Hits	350	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CDC27_HUMAN
θ value	3.0926 (rank : 163)	NC score	0.019509 (rank : 235)
Query Neighborhood Hits	267	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CJ118_HUMAN
θ value	3.0926 (rank : 164)	NC score	0.023270 (rank : 210)
Query Neighborhood Hits	267	Target Neighborhood Hits	937	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CKAP4_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.027876 (rank : 189)
Query Neighborhood Hits	267	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CNKR1_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.023591 (rank : 208)
Query Neighborhood Hits	267	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CROCC_MOUSE
θ value	3.0926 (rank : 167)	NC score	0.023390 (rank : 209)
Query Neighborhood Hits	267	Target Neighborhood Hits	1460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CUTL2_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.036870 (rank : 150)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

EVC_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.034840 (rank : 161)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

FOXP4_MOUSE
θ value	3.0926 (rank : 170)	NC score	0.014105 (rank : 262)
Query Neighborhood Hits	267	Target Neighborhood Hits	211	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

MAGC1_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.026322 (rank : 194)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	53
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NMDE4_MOUSE
θ value	3.0926 (rank : 172)	NC score	0.010101 (rank : 279)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

PCD15_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.007000 (rank : 294)
Query Neighborhood Hits	267	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PTPRF_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.003772 (rank : 302)
Query Neighborhood Hits	267	Target Neighborhood Hits	489	Shared Neighborhood Hits	6
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SHAN1_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.034137 (rank : 165)
Query Neighborhood Hits	267	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TAF6_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.024813 (rank : 202)
Query Neighborhood Hits	267	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

TENS4_MOUSE
θ value	3.0926 (rank : 177)	NC score	0.034119 (rank : 166)
Query Neighborhood Hits	267	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

TLE1_HUMAN
θ value	3.0926 (rank : 178)	NC score	0.046484 (rank : 114)
Query Neighborhood Hits	267	Target Neighborhood Hits	485	Shared Neighborhood Hits	46
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

UB7I1_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.026076 (rank : 196)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

ZFYV9_HUMAN
θ value	3.0926 (rank : 180)	NC score	0.018641 (rank : 236)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

CDX2_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.008426 (rank : 288)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	8
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

CI079_HUMAN
θ value	4.03905 (rank : 182)	NC score	0.043339 (rank : 122)
Query Neighborhood Hits	267	Target Neighborhood Hits	288	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

GGN_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.040234 (rank : 135)
Query Neighborhood Hits	267	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRLF1_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.021544 (rank : 220)
Query Neighborhood Hits	267	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

IL3RB_MOUSE
θ value	4.03905 (rank : 185)	NC score	0.044833 (rank : 117)
Query Neighborhood Hits	267	Target Neighborhood Hits	355	Shared Neighborhood Hits	56
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

NFAC4_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.017377 (rank : 245)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PHF2_MOUSE
θ value	4.03905 (rank : 187)	NC score	0.013029 (rank : 269)
Query Neighborhood Hits	267	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

RAI1_MOUSE
θ value	4.03905 (rank : 188)	NC score	0.059527 (rank : 68)
Query Neighborhood Hits	267	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RANB9_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.033874 (rank : 167)
Query Neighborhood Hits	267	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RGS3_MOUSE
θ value	4.03905 (rank : 190)	NC score	0.084300 (rank : 24)
Query Neighborhood Hits	267	Target Neighborhood Hits	1621	Shared Neighborhood Hits	163
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

S45A1_HUMAN
θ value	4.03905 (rank : 191)	NC score	0.015020 (rank : 255)
Query Neighborhood Hits	267	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2W3, Q5VY46, Q5VY49	Gene names	SLC45A1, DNB5
Domain Architecture	No domain graphic available
Description	Proton-associated sugar transporter A (PAST-A) (Solute carrier family 45 member 1) (Deleted in neuroblastoma 5 protein) (DNb-5).

SRRM2_HUMAN
θ value	4.03905 (rank : 192)	NC score	0.052987 (rank : 95)
Query Neighborhood Hits	267	Target Neighborhood Hits	1296	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYNJ1_MOUSE
θ value	4.03905 (rank : 193)	NC score	0.037754 (rank : 144)
Query Neighborhood Hits	267	Target Neighborhood Hits	516	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TIRAP_MOUSE
θ value	4.03905 (rank : 194)	NC score	0.035692 (rank : 155)
Query Neighborhood Hits	267	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

TLE1_MOUSE
θ value	4.03905 (rank : 195)	NC score	0.042398 (rank : 128)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

YLPM1_MOUSE
θ value	4.03905 (rank : 196)	NC score	0.041153 (rank : 132)
Query Neighborhood Hits	267	Target Neighborhood Hits	505	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZDHC8_MOUSE
θ value	4.03905 (rank : 197)	NC score	0.013775 (rank : 264)
Query Neighborhood Hits	267	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZN687_HUMAN
θ value	4.03905 (rank : 198)	NC score	0.020218 (rank : 228)
Query Neighborhood Hits	267	Target Neighborhood Hits	1244	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ZN687_MOUSE
θ value	4.03905 (rank : 199)	NC score	0.013415 (rank : 266)
Query Neighborhood Hits	267	Target Neighborhood Hits	913	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CT2NL_HUMAN
θ value	5.27518 (rank : 200)	NC score	0.030836 (rank : 178)
Query Neighborhood Hits	267	Target Neighborhood Hits	1059	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DAG1_HUMAN
θ value	5.27518 (rank : 201)	NC score	0.025678 (rank : 198)
Query Neighborhood Hits	267	Target Neighborhood Hits	104	Shared Neighborhood Hits	16
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

EFS_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.022154 (rank : 218)
Query Neighborhood Hits	267	Target Neighborhood Hits	348	Shared Neighborhood Hits	36
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

IRX4_MOUSE
θ value	5.27518 (rank : 203)	NC score	0.009668 (rank : 282)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

KIF3B_MOUSE
θ value	5.27518 (rank : 204)	NC score	0.014401 (rank : 258)
Query Neighborhood Hits	267	Target Neighborhood Hits	533	Shared Neighborhood Hits	26
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MYO5C_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.018019 (rank : 241)
Query Neighborhood Hits	267	Target Neighborhood Hits	1206	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NCOR2_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.036180 (rank : 154)
Query Neighborhood Hits	267	Target Neighborhood Hits	790	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NRG3_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.017591 (rank : 244)
Query Neighborhood Hits	267	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

RAF1_MOUSE
θ value	5.27518 (rank : 208)	NC score	0.005113 (rank : 299)
Query Neighborhood Hits	267	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RIN3_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.034854 (rank : 160)
Query Neighborhood Hits	267	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TESK1_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.004814 (rank : 301)
Query Neighborhood Hits	267	Target Neighborhood Hits	862	Shared Neighborhood Hits	24
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TIEG3_MOUSE
θ value	5.27518 (rank : 211)	NC score	0.013198 (rank : 267)
Query Neighborhood Hits	267	Target Neighborhood Hits	774	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

TP53B_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.048492 (rank : 111)
Query Neighborhood Hits	267	Target Neighborhood Hits	644	Shared Neighborhood Hits	71
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ZC3H3_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.022003 (rank : 219)
Query Neighborhood Hits	267	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ZN438_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.027203 (rank : 192)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN541_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.029924 (rank : 182)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

ANLN_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.017971 (rank : 242)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CCNK_MOUSE
θ value	6.88961 (rank : 217)	NC score	0.038377 (rank : 140)
Query Neighborhood Hits	267	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CIC_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.044102 (rank : 120)
Query Neighborhood Hits	267	Target Neighborhood Hits	742	Shared Neighborhood Hits	90
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CJ118_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.026166 (rank : 195)
Query Neighborhood Hits	267	Target Neighborhood Hits	1132	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CORO7_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.014302 (rank : 261)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

CSF1_MOUSE
θ value	6.88961 (rank : 221)	NC score	0.022397 (rank : 216)
Query Neighborhood Hits	267	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

EP300_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.053227 (rank : 94)
Query Neighborhood Hits	267	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GGA1_HUMAN
θ value	6.88961 (rank : 223)	NC score	0.032439 (rank : 172)
Query Neighborhood Hits	267	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

IASPP_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.020268 (rank : 227)
Query Neighborhood Hits	267	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

IRX3_MOUSE
θ value	6.88961 (rank : 225)	NC score	0.011540 (rank : 273)
Query Neighborhood Hits	267	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

KCNK4_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.009728 (rank : 281)
Query Neighborhood Hits	267	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

NCOA3_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.015472 (rank : 251)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PCLO_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.068053 (rank : 40)
Query Neighborhood Hits	267	Target Neighborhood Hits	2275	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

POGZ_MOUSE
θ value	6.88961 (rank : 229)	NC score	0.009365 (rank : 283)
Query Neighborhood Hits	267	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

PRR11_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.016620 (rank : 246)
Query Neighborhood Hits	267	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHE0, Q3V3H1	Gene names	Prr11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

PTN23_MOUSE
θ value	6.88961 (rank : 231)	NC score	0.034383 (rank : 163)
Query Neighborhood Hits	267	Target Neighborhood Hits	726	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SFPQ_MOUSE
θ value	6.88961 (rank : 232)	NC score	0.030824 (rank : 179)
Query Neighborhood Hits	267	Target Neighborhood Hits	958	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SGIP1_MOUSE
θ value	6.88961 (rank : 233)	NC score	0.045673 (rank : 116)
Query Neighborhood Hits	267	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRGP2_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.021175 (rank : 224)
Query Neighborhood Hits	267	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

STON1_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.010634 (rank : 276)
Query Neighborhood Hits	267	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TCGAP_HUMAN
θ value	6.88961 (rank : 236)	NC score	0.050064 (rank : 107)
Query Neighborhood Hits	267	Target Neighborhood Hits	872	Shared Neighborhood Hits	99
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ZAN_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.024926 (rank : 201)
Query Neighborhood Hits	267	Target Neighborhood Hits	808	Shared Neighborhood Hits	18
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZBT40_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.002368 (rank : 303)
Query Neighborhood Hits	267	Target Neighborhood Hits	949	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ZYX_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.012857 (rank : 270)
Query Neighborhood Hits	267	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

AFAD_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.022515 (rank : 214)
Query Neighborhood Hits	267	Target Neighborhood Hits	689	Shared Neighborhood Hits	39
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

BCL6_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.005823 (rank : 298)
Query Neighborhood Hits	267	Target Neighborhood Hits	922	Shared Neighborhood Hits	43
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

C2TA_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.008475 (rank : 287)
Query Neighborhood Hits	267	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CCNK_HUMAN
θ value	8.99809 (rank : 243)	NC score	0.013179 (rank : 268)
Query Neighborhood Hits	267	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

CDX2_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.007461 (rank : 292)
Query Neighborhood Hits	267	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

DOT1L_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.041518 (rank : 130)
Query Neighborhood Hits	267	Target Neighborhood Hits	660	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DREB_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.018363 (rank : 237)
Query Neighborhood Hits	267	Target Neighborhood Hits	450	Shared Neighborhood Hits	31
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

GGN_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.055816 (rank : 82)
Query Neighborhood Hits	267	Target Neighborhood Hits	311	Shared Neighborhood Hits	45
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

I15RA_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.014456 (rank : 257)
Query Neighborhood Hits	267	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q60819, Q80Z90, Q80Z91, Q80Z92, Q8R5E4	Gene names	Il15ra
Domain Architecture	No domain graphic available
Description	Interleukin-15 receptor alpha chain precursor (IL-15R-alpha) (IL- 15RA).

K0310_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.040214 (rank : 136)
Query Neighborhood Hits	267	Target Neighborhood Hits	420	Shared Neighborhood Hits	57
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K1802_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.044663 (rank : 118)
Query Neighborhood Hits	267	Target Neighborhood Hits	1378	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KLF11_MOUSE
θ value	8.99809 (rank : 251)	NC score	0.006588 (rank : 297)
Query Neighborhood Hits	267	Target Neighborhood Hits	714	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

M4K1_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.006729 (rank : 296)
Query Neighborhood Hits	267	Target Neighborhood Hits	884	Shared Neighborhood Hits	24
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

MAGAC_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.004876 (rank : 300)
Query Neighborhood Hits	267	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P43365, Q9NSD3	Gene names	MAGEA12, MAGE12
Domain Architecture
Description	Melanoma-associated antigen 12 (MAGE-12 antigen) (MAGE12F).

MAP2_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.029648 (rank : 185)
Query Neighborhood Hits	267	Target Neighborhood Hits	348	Shared Neighborhood Hits	43
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MAST4_HUMAN
θ value	8.99809 (rank : 255)	NC score	0.020925 (rank : 226)
Query Neighborhood Hits	267	Target Neighborhood Hits	1804	Shared Neighborhood Hits	124
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MD1L1_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.020045 (rank : 230)
Query Neighborhood Hits	267	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

RAI14_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.027401 (rank : 191)
Query Neighborhood Hits	267	Target Neighborhood Hits	1367	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RFX1_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.009189 (rank : 284)
Query Neighborhood Hits	267	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

RREB1_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.007922 (rank : 291)
Query Neighborhood Hits	267	Target Neighborhood Hits	879	Shared Neighborhood Hits	37
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SOCS7_MOUSE
θ value	8.99809 (rank : 260)	NC score	0.008707 (rank : 286)
Query Neighborhood Hits	267	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

SYN2_MOUSE
θ value	8.99809 (rank : 261)	NC score	0.014835 (rank : 256)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	26
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

TACC2_MOUSE
θ value	8.99809 (rank : 262)	NC score	0.033490 (rank : 170)
Query Neighborhood Hits	267	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TEKT2_HUMAN
θ value	8.99809 (rank : 263)	NC score	0.018213 (rank : 239)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

TIAM1_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.008419 (rank : 289)
Query Neighborhood Hits	267	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

TITIN_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.010079 (rank : 280)
Query Neighborhood Hits	267	Target Neighborhood Hits	2923	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI66_MOUSE
θ value	8.99809 (rank : 266)	NC score	0.037101 (rank : 149)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WBS14_MOUSE
θ value	8.99809 (rank : 267)	NC score	0.015519 (rank : 250)
Query Neighborhood Hits	267	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

BAP29_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.055976 (rank : 81)
Query Neighborhood Hits	267	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

BAT2_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.065936 (rank : 50)
Query Neighborhood Hits	267	Target Neighborhood Hits	947	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BSN_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.085222 (rank : 23)
Query Neighborhood Hits	267	Target Neighborhood Hits	2057	Shared Neighborhood Hits	174
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CEL_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.051904 (rank : 100)
Query Neighborhood Hits	267	Target Neighborhood Hits	896	Shared Neighborhood Hits	105
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CK024_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.061745 (rank : 60)
Query Neighborhood Hits	267	Target Neighborhood Hits	408	Shared Neighborhood Hits	77
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CO039_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.051530 (rank : 102)
Query Neighborhood Hits	267	Target Neighborhood Hits	445	Shared Neighborhood Hits	80
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

FA47A_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.067703 (rank : 42)
Query Neighborhood Hits	267	Target Neighborhood Hits	451	Shared Neighborhood Hits	72
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FA47B_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.060406 (rank : 64)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

K1802_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.066539 (rank : 48)
Query Neighborhood Hits	267	Target Neighborhood Hits	1596	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LCP2_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.058174 (rank : 75)
Query Neighborhood Hits	267	Target Neighborhood Hits	531	Shared Neighborhood Hits	76
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LPP_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.051576 (rank : 101)
Query Neighborhood Hits	267	Target Neighborhood Hits	775	Shared Neighborhood Hits	106
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MAGE1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.071967 (rank : 35)
Query Neighborhood Hits	267	Target Neighborhood Hits	1389	Shared Neighborhood Hits	151
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MDC1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.097983 (rank : 14)
Query Neighborhood Hits	267	Target Neighborhood Hits	1446	Shared Neighborhood Hits	143
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.096903 (rank : 16)
Query Neighborhood Hits	267	Target Neighborhood Hits	998	Shared Neighborhood Hits	133
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MKL1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.059122 (rank : 70)
Query Neighborhood Hits	267	Target Neighborhood Hits	667	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MUC1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.088465 (rank : 21)
Query Neighborhood Hits	267	Target Neighborhood Hits	975	Shared Neighborhood Hits	124
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.082890 (rank : 25)
Query Neighborhood Hits	267	Target Neighborhood Hits	1202	Shared Neighborhood Hits	139
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.078442 (rank : 31)
Query Neighborhood Hits	267	Target Neighborhood Hits	1076	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NFH_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.066685 (rank : 46)
Query Neighborhood Hits	267	Target Neighborhood Hits	2247	Shared Neighborhood Hits	168
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OBF1_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.062222 (rank : 58)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

OGFR_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.091647 (rank : 20)
Query Neighborhood Hits	267	Target Neighborhood Hits	1582	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCLO_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.067774 (rank : 41)
Query Neighborhood Hits	267	Target Neighborhood Hits	2046	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PI5PA_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.058362 (rank : 74)
Query Neighborhood Hits	267	Target Neighborhood Hits	749	Shared Neighborhood Hits	109
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRRT3_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.092528 (rank : 18)
Query Neighborhood Hits	267	Target Neighborhood Hits	998	Shared Neighborhood Hits	136
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PSL1_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.055231 (rank : 86)
Query Neighborhood Hits	267	Target Neighborhood Hits	650	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RGS3_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.063377 (rank : 54)
Query Neighborhood Hits	267	Target Neighborhood Hits	1375	Shared Neighborhood Hits	146
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RTP3_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.078721 (rank : 29)
Query Neighborhood Hits	267	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

SAPS1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.059784 (rank : 67)
Query Neighborhood Hits	267	Target Neighborhood Hits	704	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SELPL_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.062730 (rank : 56)
Query Neighborhood Hits	267	Target Neighborhood Hits	588	Shared Neighborhood Hits	86
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SON_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.086433 (rank : 22)
Query Neighborhood Hits	267	Target Neighborhood Hits	1568	Shared Neighborhood Hits	164
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SON_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.054052 (rank : 89)
Query Neighborhood Hits	267	Target Neighborhood Hits	957	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPR1B_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.055519 (rank : 83)
Query Neighborhood Hits	267	Target Neighborhood Hits	395	Shared Neighborhood Hits	69
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SRRM1_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.060015 (rank : 66)
Query Neighborhood Hits	267	Target Neighborhood Hits	966	Shared Neighborhood Hits	103
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.066759 (rank : 45)
Query Neighborhood Hits	267	Target Neighborhood Hits	1470	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TARSH_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.080950 (rank : 26)
Query Neighborhood Hits	267	Target Neighborhood Hits	768	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TXND2_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.051137 (rank : 103)
Query Neighborhood Hits	267	Target Neighborhood Hits	793	Shared Neighborhood Hits	77
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WIRE_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.052619 (rank : 97)
Query Neighborhood Hits	267	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

Hits sorted by NC score

HSF1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	267
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF1_HUMAN
NC score	0.942551 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	85
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HSF4_HUMAN
NC score	0.857980 (rank : 3)	θ value	8.81223e-72 (rank : 5)
Query Neighborhood Hits	267	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULV5, Q99472, Q9ULV6	Gene names	HSF4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (hHSF4).

HSF4_MOUSE
NC score	0.857710 (rank : 4)	θ value	4.83544e-70 (rank : 6)
Query Neighborhood Hits	267	Target Neighborhood Hits	57	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

HSF2_MOUSE
NC score	0.834754 (rank : 5)	θ value	2.73936e-73 (rank : 4)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_HUMAN
NC score	0.834253 (rank : 6)	θ value	4.22625e-74 (rank : 3)
Query Neighborhood Hits	267	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSFY1_HUMAN
NC score	0.495755 (rank : 7)	θ value	1.53129e-07 (rank : 7)
Query Neighborhood Hits	267	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q96LI6, Q7Z4L8, Q9BZA2, Q9BZA3	Gene names	HSFY1, HSF2L, HSFY
Domain Architecture
Description	Heat shock transcription factor, Y-linked (Heat shock transcription factor 2-like protein) (HSF2-like).

NACAM_MOUSE
NC score	0.132552 (rank : 8)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	267	Target Neighborhood Hits	1866	Shared Neighborhood Hits	180
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CJ078_MOUSE
NC score	0.122567 (rank : 9)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	267	Target Neighborhood Hits	559	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MLL3_HUMAN
NC score	0.108437 (rank : 10)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	267	Target Neighborhood Hits	1644	Shared Neighborhood Hits	152
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
NC score	0.103802 (rank : 11)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	267	Target Neighborhood Hits	1399	Shared Neighborhood Hits	133
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PCQAP_HUMAN
NC score	0.103015 (rank : 12)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	267	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

BCL9_HUMAN
NC score	0.102952 (rank : 13)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	267	Target Neighborhood Hits	1008	Shared Neighborhood Hits	126
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

MDC1_HUMAN
NC score	0.097983 (rank : 14)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	267	Target Neighborhood Hits	1446	Shared Neighborhood Hits	143
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BCL9_MOUSE
NC score	0.097352 (rank : 15)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	267	Target Neighborhood Hits	770	Shared Neighborhood Hits	104
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MDC1_MOUSE
NC score	0.096903 (rank : 16)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	267	Target Neighborhood Hits	998	Shared Neighborhood Hits	133
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PCQAP_MOUSE
NC score	0.095801 (rank : 17)	θ value	0.0193708 (rank : 21)
Query Neighborhood Hits	267	Target Neighborhood Hits	506	Shared Neighborhood Hits	43
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PRRT3_HUMAN
NC score	0.092528 (rank : 18)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	267	Target Neighborhood Hits	998	Shared Neighborhood Hits	136
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MLL2_HUMAN
NC score	0.092469 (rank : 19)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	267	Target Neighborhood Hits	1788	Shared Neighborhood Hits	134
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OGFR_HUMAN
NC score	0.091647 (rank : 20)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	267	Target Neighborhood Hits	1582	Shared Neighborhood Hits	158
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MUC1_HUMAN
NC score	0.088465 (rank : 21)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	267	Target Neighborhood Hits	975	Shared Neighborhood Hits	124
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SON_HUMAN
NC score	0.086433 (rank : 22)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	267	Target Neighborhood Hits	1568	Shared Neighborhood Hits	164
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

BSN_MOUSE
NC score	0.085222 (rank : 23)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	267	Target Neighborhood Hits	2057	Shared Neighborhood Hits	174
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

RGS3_MOUSE
NC score	0.084300 (rank : 24)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	267	Target Neighborhood Hits	1621	Shared Neighborhood Hits	163
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NCOA6_HUMAN
NC score	0.082890 (rank : 25)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	267	Target Neighborhood Hits	1202	Shared Neighborhood Hits	139
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TARSH_HUMAN
NC score	0.080950 (rank : 26)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	267	Target Neighborhood Hits	768	Shared Neighborhood Hits	108
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

WASIP_HUMAN
NC score	0.080525 (rank : 27)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	267	Target Neighborhood Hits	458	Shared Neighborhood Hits	51
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

BAP29_MOUSE
NC score	0.079968 (rank : 28)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	24
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

RTP3_MOUSE
NC score	0.078721 (rank : 29)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	267	Target Neighborhood Hits	374	Shared Neighborhood Hits	83
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

CBP_MOUSE
NC score	0.078703 (rank : 30)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	267	Target Neighborhood Hits	1051	Shared Neighborhood Hits	119
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NCOA6_MOUSE
NC score	0.078442 (rank : 31)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	267	Target Neighborhood Hits	1076	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

WASIP_MOUSE
NC score	0.077681 (rank : 32)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	267	Target Neighborhood Hits	392	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

MUC7_HUMAN
NC score	0.076713 (rank : 33)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	267	Target Neighborhood Hits	538	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BSN_HUMAN
NC score	0.072535 (rank : 34)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	267	Target Neighborhood Hits	1537	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

MAGE1_HUMAN
NC score	0.071967 (rank : 35)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	267	Target Neighborhood Hits	1389	Shared Neighborhood Hits	151
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TAF4_HUMAN
NC score	0.071193 (rank : 36)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	267	Target Neighborhood Hits	687	Shared Neighborhood Hits	70
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

GSCR1_HUMAN
NC score	0.070119 (rank : 37)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	267	Target Neighborhood Hits	674	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

CBP_HUMAN
NC score	0.069275 (rank : 38)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	267	Target Neighborhood Hits	941	Shared Neighborhood Hits	97
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BAT2_HUMAN
NC score	0.068925 (rank : 39)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	267	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_MOUSE
NC score	0.068053 (rank : 40)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	267	Target Neighborhood Hits	2275	Shared Neighborhood Hits	171
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PCLO_HUMAN
NC score	0.067774 (rank : 41)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	267	Target Neighborhood Hits	2046	Shared Neighborhood Hits	165
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

FA47A_HUMAN
NC score	0.067703 (rank : 42)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	267	Target Neighborhood Hits	451	Shared Neighborhood Hits	72
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BAP31_MOUSE
NC score	0.067624 (rank : 43)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

CEND3_MOUSE
NC score	0.067230 (rank : 44)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	267	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

SRRM2_MOUSE
NC score	0.066759 (rank : 45)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	267	Target Neighborhood Hits	1470	Shared Neighborhood Hits	132
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_MOUSE
NC score	0.066685 (rank : 46)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	267	Target Neighborhood Hits	2247	Shared Neighborhood Hits	168
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SETD2_HUMAN
NC score	0.066677 (rank : 47)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

K1802_MOUSE
NC score	0.066539 (rank : 48)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	267	Target Neighborhood Hits	1596	Shared Neighborhood Hits	145
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASF1_HUMAN
NC score	0.066116 (rank : 49)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	267	Target Neighborhood Hits	260	Shared Neighborhood Hits	39
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

BAT2_MOUSE
NC score	0.065936 (rank : 50)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	267	Target Neighborhood Hits	947	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

WASF1_MOUSE
NC score	0.065138 (rank : 51)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

JPH2_HUMAN
NC score	0.064977 (rank : 52)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	267	Target Neighborhood Hits	639	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

CSKI1_MOUSE
NC score	0.064699 (rank : 53)	θ value	0.00665767 (rank : 14)
Query Neighborhood Hits	267	Target Neighborhood Hits	1031	Shared Neighborhood Hits	109
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RGS3_HUMAN
NC score	0.063377 (rank : 54)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	267	Target Neighborhood Hits	1375	Shared Neighborhood Hits	146
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ENAH_MOUSE
NC score	0.062899 (rank : 55)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	267	Target Neighborhood Hits	919	Shared Neighborhood Hits	77
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SELPL_MOUSE
NC score	0.062730 (rank : 56)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	267	Target Neighborhood Hits	588	Shared Neighborhood Hits	86
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SGIP1_HUMAN
NC score	0.062726 (rank : 57)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

OBF1_HUMAN
NC score	0.062222 (rank : 58)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	53
SwissProt Accessions	Q16633, Q14983	Gene names	POU2AF1, OBF1
Domain Architecture	No domain graphic available
Description	POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (OCT-binding factor 1) (BOB-1) (OCA-B).

WIRE_MOUSE
NC score	0.061953 (rank : 59)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	267	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CK024_HUMAN
NC score	0.061745 (rank : 60)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	267	Target Neighborhood Hits	408	Shared Neighborhood Hits	77
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

JPH2_MOUSE
NC score	0.061570 (rank : 61)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	267	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

BAP31_HUMAN
NC score	0.061179 (rank : 62)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	267	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

CIC_HUMAN
NC score	0.061119 (rank : 63)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	267	Target Neighborhood Hits	992	Shared Neighborhood Hits	111
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FA47B_HUMAN
NC score	0.060406 (rank : 64)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

MAML1_HUMAN
NC score	0.060340 (rank : 65)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	267	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

SRRM1_MOUSE
NC score	0.060015 (rank : 66)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	267	Target Neighborhood Hits	966	Shared Neighborhood Hits	103
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SAPS1_HUMAN
NC score	0.059784 (rank : 67)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	267	Target Neighborhood Hits	704	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

RAI1_MOUSE
NC score	0.059527 (rank : 68)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	267	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CXXC6_HUMAN
NC score	0.059413 (rank : 69)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	267	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

MKL1_MOUSE
NC score	0.059122 (rank : 70)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	267	Target Neighborhood Hits	667	Shared Neighborhood Hits	102
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

UBE4B_HUMAN
NC score	0.058931 (rank : 71)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

CSKI1_HUMAN
NC score	0.058617 (rank : 72)	θ value	0.00102713 (rank : 10)
Query Neighborhood Hits	267	Target Neighborhood Hits	997	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MLL4_HUMAN
NC score	0.058411 (rank : 73)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	267	Target Neighborhood Hits	722	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PI5PA_HUMAN
NC score	0.058362 (rank : 74)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	267	Target Neighborhood Hits	749	Shared Neighborhood Hits	109
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

LCP2_HUMAN
NC score	0.058174 (rank : 75)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	267	Target Neighborhood Hits	531	Shared Neighborhood Hits	76
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MUC2_HUMAN
NC score	0.058107 (rank : 76)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	64
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MAML3_HUMAN
NC score	0.057367 (rank : 77)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	267	Target Neighborhood Hits	323	Shared Neighborhood Hits	34
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

CEND3_HUMAN
NC score	0.056924 (rank : 78)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	267	Target Neighborhood Hits	275	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RTN4_HUMAN
NC score	0.056841 (rank : 79)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

CG1_HUMAN
NC score	0.056570 (rank : 80)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	45
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

BAP29_HUMAN
NC score	0.055976 (rank : 81)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	267	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UHQ4, O95003	Gene names	BCAP29, BAP29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

GGN_MOUSE
NC score	0.055816 (rank : 82)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	267	Target Neighborhood Hits	311	Shared Neighborhood Hits	45
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SPR1B_MOUSE
NC score	0.055519 (rank : 83)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	267	Target Neighborhood Hits	395	Shared Neighborhood Hits	69
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

MORC2_HUMAN
NC score	0.055384 (rank : 84)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	267	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SDC3_MOUSE
NC score	0.055332 (rank : 85)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	267	Target Neighborhood Hits	107	Shared Neighborhood Hits	8
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

PSL1_HUMAN
NC score	0.055231 (rank : 86)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	267	Target Neighborhood Hits	650	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

GGA3_MOUSE
NC score	0.055044 (rank : 87)	θ value	0.00134147 (rank : 11)
Query Neighborhood Hits	267	Target Neighborhood Hits	148	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

SYNP2_MOUSE
NC score	0.054674 (rank : 88)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	28
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

SON_MOUSE
NC score	0.054052 (rank : 89)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	267	Target Neighborhood Hits	957	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ANK2_HUMAN
NC score	0.054036 (rank : 90)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	267	Target Neighborhood Hits	1615	Shared Neighborhood Hits	135
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TLE4_MOUSE
NC score	0.053608 (rank : 91)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	267	Target Neighborhood Hits	482	Shared Neighborhood Hits	43
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.053497 (rank : 92)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	267	Target Neighborhood Hits	477	Shared Neighborhood Hits	43
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

P53_HUMAN
NC score	0.053314 (rank : 93)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

EP300_HUMAN
NC score	0.053227 (rank : 94)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	267	Target Neighborhood Hits	821	Shared Neighborhood Hits	71
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SRRM2_HUMAN
NC score	0.052987 (rank : 95)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	267	Target Neighborhood Hits	1296	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SMOO_HUMAN
NC score	0.052975 (rank : 96)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	267	Target Neighborhood Hits	391	Shared Neighborhood Hits	42
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

WIRE_HUMAN
NC score	0.052619 (rank : 97)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	267	Target Neighborhood Hits	329	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

APXL_HUMAN
NC score	0.052005 (rank : 98)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	267	Target Neighborhood Hits	553	Shared Neighborhood Hits	56
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

ATN1_HUMAN
NC score	0.051934 (rank : 99)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	267	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CEL_HUMAN
NC score	0.051904 (rank : 100)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	267	Target Neighborhood Hits	896	Shared Neighborhood Hits	105
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

LPP_HUMAN
NC score	0.051576 (rank : 101)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	267	Target Neighborhood Hits	775	Shared Neighborhood Hits	106
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CO039_MOUSE
NC score	0.051530 (rank : 102)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	267	Target Neighborhood Hits	445	Shared Neighborhood Hits	80
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

TXND2_HUMAN
NC score	0.051137 (rank : 103)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	267	Target Neighborhood Hits	793	Shared Neighborhood Hits	77
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

SDC3_HUMAN
NC score	0.051123 (rank : 104)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	267	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	O75056, Q5T1Z6, Q5T1Z7, Q96CT3, Q96PR8	Gene names	SDC3, KIAA0468
Domain Architecture
Description	Syndecan-3 (SYND3).

IRS2_MOUSE
NC score	0.050669 (rank : 105)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ZAN_HUMAN
NC score	0.050143 (rank : 106)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	267	Target Neighborhood Hits	679	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TCGAP_HUMAN
NC score	0.050064 (rank : 107)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	267	Target Neighborhood Hits	872	Shared Neighborhood Hits	99
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

IL3B2_MOUSE
NC score	0.049495 (rank : 108)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	267	Target Neighborhood Hits	372	Shared Neighborhood Hits	55
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

MNT_MOUSE
NC score	0.048990 (rank : 109)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	267	Target Neighborhood Hits	432	Shared Neighborhood Hits	52
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PDZD2_HUMAN
NC score	0.048747 (rank : 110)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	267	Target Neighborhood Hits	772	Shared Neighborhood Hits	78
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TP53B_MOUSE
NC score	0.048492 (rank : 111)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	267	Target Neighborhood Hits	644	Shared Neighborhood Hits	71
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

PRG4_HUMAN
NC score	0.047829 (rank : 112)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	267	Target Neighborhood Hits	764	Shared Neighborhood Hits	63
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MEGF9_MOUSE
NC score	0.047242 (rank : 113)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	267	Target Neighborhood Hits	896	Shared Neighborhood Hits	104
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TLE1_HUMAN
NC score	0.046484 (rank : 114)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	267	Target Neighborhood Hits	485	Shared Neighborhood Hits	46
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

RAPH1_HUMAN
NC score	0.046045 (rank : 115)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	267	Target Neighborhood Hits	593	Shared Neighborhood Hits	71
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SGIP1_MOUSE
NC score	0.045673 (rank : 116)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	267	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

IL3RB_MOUSE
NC score	0.044833 (rank : 117)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	267	Target Neighborhood Hits	355	Shared Neighborhood Hits	56
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

K1802_HUMAN
NC score	0.044663 (rank : 118)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	267	Target Neighborhood Hits	1378	Shared Neighborhood Hits	126
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MOR2A_MOUSE
NC score	0.044550 (rank : 119)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

CIC_MOUSE
NC score	0.044102 (rank : 120)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	267	Target Neighborhood Hits	742	Shared Neighborhood Hits	90
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MKL1_HUMAN
NC score	0.043480 (rank : 121)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	20
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

CI079_HUMAN
NC score	0.043339 (rank : 122)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	267	Target Neighborhood Hits	288	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

RP1L1_HUMAN
NC score	0.043161 (rank : 123)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	267	Target Neighborhood Hits	1072	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

UVRAG_HUMAN
NC score	0.043114 (rank : 124)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	267	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

TRI66_HUMAN
NC score	0.043063 (rank : 125)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	267	Target Neighborhood Hits	479	Shared Neighborhood Hits	48
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PRGC2_HUMAN
NC score	0.042888 (rank : 126)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	267	Target Neighborhood Hits	272	Shared Neighborhood Hits	33
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

CSKI2_MOUSE
NC score	0.042882 (rank : 127)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	267	Target Neighborhood Hits	812	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TLE1_MOUSE
NC score	0.042398 (rank : 128)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	45
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

RCOR3_HUMAN
NC score	0.042264 (rank : 129)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

DOT1L_HUMAN
NC score	0.041518 (rank : 130)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	267	Target Neighborhood Hits	660	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MY18B_HUMAN
NC score	0.041233 (rank : 131)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	267	Target Neighborhood Hits	1299	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

YLPM1_MOUSE
NC score	0.041153 (rank : 132)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	267	Target Neighborhood Hits	505	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

FMN1A_MOUSE
NC score	0.040831 (rank : 133)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	267	Target Neighborhood Hits	423	Shared Neighborhood Hits	54
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

TRIPB_HUMAN
NC score	0.040640 (rank : 134)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	267	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

GGN_HUMAN
NC score	0.040234 (rank : 135)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	267	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

K0310_HUMAN
NC score	0.040214 (rank : 136)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	267	Target Neighborhood Hits	420	Shared Neighborhood Hits	57
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

RIMB1_HUMAN
NC score	0.039505 (rank : 137)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	267	Target Neighborhood Hits	1479	Shared Neighborhood Hits	101
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

FMN1B_MOUSE
NC score	0.039342 (rank : 138)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	267	Target Neighborhood Hits	447	Shared Neighborhood Hits	50
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

TIRAP_HUMAN
NC score	0.038643 (rank : 139)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	267	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P58753, Q8N5E5	Gene names	TIRAP, MAL
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

CCNK_MOUSE
NC score	0.038377 (rank : 140)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	267	Target Neighborhood Hits	350	Shared Neighborhood Hits	42
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

UACA_HUMAN
NC score	0.038135 (rank : 141)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	267	Target Neighborhood Hits	1622	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AUTS2_HUMAN
NC score	0.038100 (rank : 142)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	267	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

HCN2_MOUSE
NC score	0.037924 (rank : 143)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	46
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

SYNJ1_MOUSE
NC score	0.037754 (rank : 144)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	267	Target Neighborhood Hits	516	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

3BP1_HUMAN
NC score	0.037752 (rank : 145)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	267	Target Neighborhood Hits	376	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

KCNH2_HUMAN
NC score	0.037579 (rank : 146)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

CDT1_MOUSE
NC score	0.037543 (rank : 147)	θ value	0.813845 (rank : 79)
Query Neighborhood Hits	267	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

VGF_HUMAN
NC score	0.037419 (rank : 148)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	267	Target Neighborhood Hits	167	Shared Neighborhood Hits	12
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

TRI66_MOUSE
NC score	0.037101 (rank : 149)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CUTL2_HUMAN
NC score	0.036870 (rank : 150)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MADCA_HUMAN
NC score	0.036547 (rank : 151)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	267	Target Neighborhood Hits	221	Shared Neighborhood Hits	22
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

CENG1_MOUSE
NC score	0.036307 (rank : 152)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	267	Target Neighborhood Hits	531	Shared Neighborhood Hits	30
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

E2F4_HUMAN
NC score	0.036239 (rank : 153)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	267	Target Neighborhood Hits	188	Shared Neighborhood Hits	29
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

NCOR2_MOUSE
NC score	0.036180 (rank : 154)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	267	Target Neighborhood Hits	790	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

TIRAP_MOUSE
NC score	0.035692 (rank : 155)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	267	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q99JY1, Q91ZW0	Gene names	Tirap, Mal
Domain Architecture
Description	Toll-interleukin 1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (MyD88 adapter-like protein) (Adaptor protein Wyatt).

ETV3_HUMAN
NC score	0.035416 (rank : 156)	θ value	1.06291 (rank : 93)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	50
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

CUTL2_MOUSE
NC score	0.035296 (rank : 157)	θ value	0.813845 (rank : 80)
Query Neighborhood Hits	267	Target Neighborhood Hits	771	Shared Neighborhood Hits	50
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

BRD4_HUMAN
NC score	0.035255 (rank : 158)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	267	Target Neighborhood Hits	851	Shared Neighborhood Hits	71
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

AFF1_HUMAN
NC score	0.035021 (rank : 159)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	267	Target Neighborhood Hits	506	Shared Neighborhood Hits	48
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

RIN3_MOUSE
NC score	0.034854 (rank : 160)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	267	Target Neighborhood Hits	239	Shared Neighborhood Hits	36
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

EVC_HUMAN
NC score	0.034840 (rank : 161)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	12
SwissProt Accessions	P57679	Gene names	EVC
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein (DWF-1).

NIN_HUMAN
NC score	0.034735 (rank : 162)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	267	Target Neighborhood Hits	1416	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PTN23_MOUSE
NC score	0.034383 (rank : 163)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	267	Target Neighborhood Hits	726	Shared Neighborhood Hits	86
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PHC3_MOUSE
NC score	0.034342 (rank : 164)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	267	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

SHAN1_HUMAN
NC score	0.034137 (rank : 165)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	267	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TENS4_MOUSE
NC score	0.034119 (rank : 166)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	267	Target Neighborhood Hits	225	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

RANB9_HUMAN
NC score	0.033874 (rank : 167)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	267	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

NF2L2_MOUSE
NC score	0.033726 (rank : 168)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	17
SwissProt Accessions	Q60795	Gene names	Nfe2l2, Nrf-2, Nrf2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2).

AP180_HUMAN
NC score	0.033678 (rank : 169)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

TACC2_MOUSE
NC score	0.033490 (rank : 170)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	267	Target Neighborhood Hits	774	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TOM40_MOUSE
NC score	0.032773 (rank : 171)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	267	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYA2, Q9Z2N1	Gene names	Tomm40, Mom35, Tom40
Domain Architecture
Description	Probable mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog).

GGA1_HUMAN
NC score	0.032439 (rank : 172)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	267	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

CENG1_HUMAN
NC score	0.032376 (rank : 173)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	267	Target Neighborhood Hits	544	Shared Neighborhood Hits	28
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

MAP9_MOUSE
NC score	0.032181 (rank : 174)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	267	Target Neighborhood Hits	529	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

HMMR_HUMAN
NC score	0.031598 (rank : 175)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	267	Target Neighborhood Hits	1082	Shared Neighborhood Hits	43
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ARHGF_HUMAN
NC score	0.031517 (rank : 176)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	267	Target Neighborhood Hits	214	Shared Neighborhood Hits	25
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

EEA1_MOUSE
NC score	0.030960 (rank : 177)	θ value	0.813845 (rank : 81)
Query Neighborhood Hits	267	Target Neighborhood Hits	1637	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CT2NL_HUMAN
NC score	0.030836 (rank : 178)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	267	Target Neighborhood Hits	1059	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

SFPQ_MOUSE
NC score	0.030824 (rank : 179)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	267	Target Neighborhood Hits	958	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CT2NL_MOUSE
NC score	0.030673 (rank : 180)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	267	Target Neighborhood Hits	902	Shared Neighborhood Hits	50
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PTN23_HUMAN
NC score	0.030170 (rank : 181)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	267	Target Neighborhood Hits	646	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

ZN541_HUMAN
NC score	0.029924 (rank : 182)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

WHRN_MOUSE
NC score	0.029775 (rank : 183)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

RCOR3_MOUSE
NC score	0.029719 (rank : 184)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	267	Target Neighborhood Hits	110	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

MAP2_HUMAN
NC score	0.029648 (rank : 185)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	267	Target Neighborhood Hits	348	Shared Neighborhood Hits	43
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

PRDM2_HUMAN
NC score	0.029082 (rank : 186)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	267	Target Neighborhood Hits	1135	Shared Neighborhood Hits	58
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

JHD3B_MOUSE
NC score	0.028790 (rank : 187)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	267	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

KCNH2_MOUSE
NC score	0.028412 (rank : 188)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

CKAP4_MOUSE
NC score	0.027876 (rank : 189)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	267	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

EEA1_HUMAN
NC score	0.027482 (rank : 190)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	267	Target Neighborhood Hits	1796	Shared Neighborhood Hits	68
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

RAI14_HUMAN
NC score	0.027401 (rank : 191)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	267	Target Neighborhood Hits	1367	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ZN438_HUMAN
NC score	0.027203 (rank : 192)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	267	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

IF4G1_HUMAN
NC score	0.026937 (rank : 193)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	267	Target Neighborhood Hits	347	Shared Neighborhood Hits	46
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MAGC1_HUMAN
NC score	0.026322 (rank : 194)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	53
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

CJ118_MOUSE
NC score	0.026166 (rank : 195)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	267	Target Neighborhood Hits	1132	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

UB7I1_HUMAN
NC score	0.026076 (rank : 196)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

RD23B_MOUSE
NC score	0.025694 (rank : 197)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	267	Target Neighborhood Hits	189	Shared Neighborhood Hits	21
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

DAG1_HUMAN
NC score	0.025678 (rank : 198)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	267	Target Neighborhood Hits	104	Shared Neighborhood Hits	16
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

KI21A_HUMAN
NC score	0.025503 (rank : 199)	θ value	0.813845 (rank : 82)
Query Neighborhood Hits	267	Target Neighborhood Hits	1543	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PER1_HUMAN
NC score	0.025204 (rank : 200)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	267	Target Neighborhood Hits	215	Shared Neighborhood Hits	23
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

ZAN_MOUSE
NC score	0.024926 (rank : 201)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	267	Target Neighborhood Hits	808	Shared Neighborhood Hits	18
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TAF6_MOUSE
NC score	0.024813 (rank : 202)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	267	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q62311	Gene names	Taf6, Taf2e
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80) (p80).

JHD3B_HUMAN
NC score	0.024604 (rank : 203)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	267	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

SRGP2_MOUSE
NC score	0.024185 (rank : 204)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	267	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TTP_HUMAN
NC score	0.024084 (rank : 205)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	267	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	P26651	Gene names	ZFP36, G0S24, TIS11A, TTP
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (G0/G1 switch regulatory protein 24).

KI21A_MOUSE
NC score	0.023989 (rank : 206)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	267	Target Neighborhood Hits	1317	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MYO5A_MOUSE
NC score	0.023730 (rank : 207)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	267	Target Neighborhood Hits	1117	Shared Neighborhood Hits	41
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

CNKR1_HUMAN
NC score	0.023591 (rank : 208)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	267	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CROCC_MOUSE
NC score	0.023390 (rank : 209)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	267	Target Neighborhood Hits	1460	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CJ118_HUMAN
NC score	0.023270 (rank : 210)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	267	Target Neighborhood Hits	937	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

SEM6B_HUMAN
NC score	0.022973 (rank : 211)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	267	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

WNK2_HUMAN
NC score	0.022842 (rank : 212)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	267	Target Neighborhood Hits	1407	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RBP2_MOUSE
NC score	0.022824 (rank : 213)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

AFAD_HUMAN
NC score	0.022515 (rank : 214)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	267	Target Neighborhood Hits	689	Shared Neighborhood Hits	39
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AKAP1_HUMAN
NC score	0.022492 (rank : 215)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	267	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

CSF1_MOUSE
NC score	0.022397 (rank : 216)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	267	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	P07141, Q8R3C8	Gene names	Csf1, Csfm
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF).

EPN1_MOUSE
NC score	0.022301 (rank : 217)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	25
SwissProt Accessions	Q80VP1, O70446	Gene names	Epn1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1).

EFS_HUMAN
NC score	0.022154 (rank : 218)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	267	Target Neighborhood Hits	348	Shared Neighborhood Hits	36
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ZC3H3_MOUSE
NC score	0.022003 (rank : 219)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	267	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

GRLF1_HUMAN
NC score	0.021544 (rank : 220)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	267	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

ABI2_HUMAN
NC score	0.021527 (rank : 221)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	267	Target Neighborhood Hits	350	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ETV3_MOUSE
NC score	0.021310 (rank : 222)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	267	Target Neighborhood Hits	128	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

MEGF9_HUMAN
NC score	0.021192 (rank : 223)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	267	Target Neighborhood Hits	557	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SRGP2_HUMAN
NC score	0.021175 (rank : 224)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	267	Target Neighborhood Hits	331	Shared Neighborhood Hits	19
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

2A5G_HUMAN
NC score	0.021074 (rank : 225)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	267	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q13362, Q14391, Q15060, Q15174	Gene names	PPP2R5C, KIAA0044
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (NY-REN-29 antigen).

MAST4_HUMAN
NC score	0.020925 (rank : 226)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	267	Target Neighborhood Hits	1804	Shared Neighborhood Hits	124
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

IASPP_HUMAN
NC score	0.020268 (rank : 227)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	267	Target Neighborhood Hits	688	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

ZN687_HUMAN
NC score	0.020218 (rank : 228)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	267	Target Neighborhood Hits	1244	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

HXA3_MOUSE
NC score	0.020134 (rank : 229)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	267	Target Neighborhood Hits	558	Shared Neighborhood Hits	41
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

MD1L1_HUMAN
NC score	0.020045 (rank : 230)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	267	Target Neighborhood Hits	893	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

RBP2_HUMAN
NC score	0.019959 (rank : 231)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	267	Target Neighborhood Hits	249	Shared Neighborhood Hits	22
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

SPEG_HUMAN
NC score	0.019945 (rank : 232)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	267	Target Neighborhood Hits	1762	Shared Neighborhood Hits	88
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

2A5G_MOUSE
NC score	0.019756 (rank : 233)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	267	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q60996, O35708, Q99KW8, Q99N67, Q99N68	Gene names	Ppp2r5c
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B' gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B subunit, B'alpha3 isoform).

WNK4_HUMAN
NC score	0.019740 (rank : 234)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	267	Target Neighborhood Hits	1043	Shared Neighborhood Hits	51
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CDC27_HUMAN
NC score	0.019509 (rank : 235)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	267	Target Neighborhood Hits	139	Shared Neighborhood Hits	8
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

ZFYV9_HUMAN
NC score	0.018641 (rank : 236)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

DREB_HUMAN
NC score	0.018363 (rank : 237)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	267	Target Neighborhood Hits	450	Shared Neighborhood Hits	31
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

SAM68_MOUSE
NC score	0.018294 (rank : 238)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	267	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q60749, Q3U8T3, Q60735, Q99M33	Gene names	Khdrbs1
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TEKT2_HUMAN
NC score	0.018213 (rank : 239)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIF3, O60638	Gene names	TEKT2
Domain Architecture
Description	Tektin-2 (Testicular tektin) (Tektin-t) (Testicular tektin B1-like protein) (Tektin-B1) (TEKTB1).

KLF13_MOUSE
NC score	0.018040 (rank : 240)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	267	Target Neighborhood Hits	757	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JJZ6, Q9ESX3, Q9JHF8	Gene names	Klf13, Bteb3, Fklf2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 13 (Transcription factor BTEB3) (Basic transcription element-binding protein 3) (BTE-binding protein 3) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Erythroid transcription factor FKLF-2).

MYO5C_HUMAN
NC score	0.018019 (rank : 241)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	267	Target Neighborhood Hits	1206	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ANLN_HUMAN
NC score	0.017971 (rank : 242)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DLGP4_HUMAN
NC score	0.017652 (rank : 243)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	267	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2H0, Q5T2Y4, Q5T2Y5, Q9H137, Q9H138, Q9H1L7	Gene names	DLGAP4, DAP4, KIAA0964
Domain Architecture
Description	Disks large-associated protein 4 (DAP-4) (SAP90/PSD-95-associated protein 4) (SAPAP4) (PSD-95/SAP90-binding protein 4).

NRG3_MOUSE
NC score	0.017591 (rank : 244)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	267	Target Neighborhood Hits	132	Shared Neighborhood Hits	10
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NFAC4_HUMAN
NC score	0.017377 (rank : 245)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

PRR11_MOUSE
NC score	0.016620 (rank : 246)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	267	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHE0, Q3V3H1	Gene names	Prr11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

MINK1_HUMAN
NC score	0.016486 (rank : 247)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	267	Target Neighborhood Hits	1477	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

HXA3_HUMAN
NC score	0.016036 (rank : 248)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	267	Target Neighborhood Hits	535	Shared Neighborhood Hits	33
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

WNK4_MOUSE
NC score	0.015864 (rank : 249)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	267	Target Neighborhood Hits	961	Shared Neighborhood Hits	47
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

WBS14_MOUSE
NC score	0.015519 (rank : 250)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	267	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

NCOA3_MOUSE
NC score	0.015472 (rank : 251)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NOTC3_HUMAN
NC score	0.015279 (rank : 252)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	267	Target Neighborhood Hits	1062	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CORO7_HUMAN
NC score	0.015219 (rank : 253)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	267	Target Neighborhood Hits	315	Shared Neighborhood Hits	12
SwissProt Accessions	P57737	Gene names	CORO7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

TNIK_HUMAN
NC score	0.015205 (rank : 254)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	267	Target Neighborhood Hits	1570	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

S45A1_HUMAN
NC score	0.015020 (rank : 255)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	267	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2W3, Q5VY46, Q5VY49	Gene names	SLC45A1, DNB5
Domain Architecture	No domain graphic available
Description	Proton-associated sugar transporter A (PAST-A) (Solute carrier family 45 member 1) (Deleted in neuroblastoma 5 protein) (DNb-5).

SYN2_MOUSE
NC score	0.014835 (rank : 256)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	267	Target Neighborhood Hits	183	Shared Neighborhood Hits	26
SwissProt Accessions	Q64332, Q6NZR0, Q9QWV7	Gene names	Syn2
Domain Architecture	No domain graphic available
Description	Synapsin-2 (Synapsin II).

I15RA_MOUSE
NC score	0.014456 (rank : 257)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	267	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q60819, Q80Z90, Q80Z91, Q80Z92, Q8R5E4	Gene names	Il15ra
Domain Architecture	No domain graphic available
Description	Interleukin-15 receptor alpha chain precursor (IL-15R-alpha) (IL- 15RA).

KIF3B_MOUSE
NC score	0.014401 (rank : 258)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	267	Target Neighborhood Hits	533	Shared Neighborhood Hits	26
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

MINK1_MOUSE
NC score	0.014377 (rank : 259)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	267	Target Neighborhood Hits	1451	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

BARH2_HUMAN
NC score	0.014305 (rank : 260)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	267	Target Neighborhood Hits	419	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NY43, Q7Z4N7	Gene names	BARHL2
Domain Architecture
Description	BarH-like 2 homeobox protein.

CORO7_MOUSE
NC score	0.014302 (rank : 261)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D2V7, Q3UDJ4, Q6P8Y8, Q8C9V7	Gene names	Coro7
Domain Architecture
Description	Coronin-7 (70 kDa WD repeat tumor rejection antigen homolog).

FOXP4_MOUSE
NC score	0.014105 (rank : 262)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	267	Target Neighborhood Hits	211	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

GLI2_HUMAN
NC score	0.014006 (rank : 263)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	267	Target Neighborhood Hits	971	Shared Neighborhood Hits	49
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

ZDHC8_MOUSE
NC score	0.013775 (rank : 264)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	267	Target Neighborhood Hits	243	Shared Neighborhood Hits	24
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

MGR1_MOUSE
NC score	0.013453 (rank : 265)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	267	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

ZN687_MOUSE
NC score	0.013415 (rank : 266)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	267	Target Neighborhood Hits	913	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

TIEG3_MOUSE
NC score	0.013198 (rank : 267)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	267	Target Neighborhood Hits	774	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

CCNK_HUMAN
NC score	0.013179 (rank : 268)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	267	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

PHF2_MOUSE
NC score	0.013029 (rank : 269)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	267	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ZYX_HUMAN
NC score	0.012857 (rank : 270)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	267	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

GAK_MOUSE
NC score	0.011772 (rank : 271)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	267	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MAST1_HUMAN
NC score	0.011750 (rank : 272)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	267	Target Neighborhood Hits	1146	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

IRX3_MOUSE
NC score	0.011540 (rank : 273)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	267	Target Neighborhood Hits	303	Shared Neighborhood Hits	15
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ZN692_HUMAN
NC score	0.010949 (rank : 274)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	267	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BU19, Q5SRA5, Q5SRA6, Q9HBC9, Q9NW93, Q9NWY6, Q9UF97	Gene names	ZNF692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

POGZ_HUMAN
NC score	0.010904 (rank : 275)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	267	Target Neighborhood Hits	745	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z3K3, O75049, Q8TDZ7, Q9Y4X7	Gene names	POGZ, KIAA0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

STON1_HUMAN
NC score	0.010634 (rank : 276)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	267	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

HXB2_HUMAN
NC score	0.010371 (rank : 277)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	267	Target Neighborhood Hits	367	Shared Neighborhood Hits	17
SwissProt Accessions	P14652, P10913, P17485	Gene names	HOXB2, HOX2H
Domain Architecture
Description	Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8).

CD2L7_HUMAN
NC score	0.010192 (rank : 278)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	267	Target Neighborhood Hits	1275	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

NMDE4_MOUSE
NC score	0.010101 (rank : 279)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	267	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

TITIN_HUMAN
NC score	0.010079 (rank : 280)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	267	Target Neighborhood Hits	2923	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

KCNK4_MOUSE
NC score	0.009728 (rank : 281)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	267	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

IRX4_MOUSE
NC score	0.009668 (rank : 282)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

POGZ_MOUSE
NC score	0.009365 (rank : 283)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	267	Target Neighborhood Hits	765	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

RFX1_MOUSE
NC score	0.009189 (rank : 284)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	267	Target Neighborhood Hits	181	Shared Neighborhood Hits	11
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

M3K6_HUMAN
NC score	0.009142 (rank : 285)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	267	Target Neighborhood Hits	889	Shared Neighborhood Hits	21
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

SOCS7_MOUSE
NC score	0.008707 (rank : 286)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	267	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

C2TA_MOUSE
NC score	0.008475 (rank : 287)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	267	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CDX2_HUMAN
NC score	0.008426 (rank : 288)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	8
SwissProt Accessions	Q99626, O00503, Q969L8	Gene names	CDX2, CDX3
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

TIAM1_HUMAN
NC score	0.008419 (rank : 289)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	267	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q13009	Gene names	TIAM1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

HIC1_MOUSE
NC score	0.007976 (rank : 290)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	267	Target Neighborhood Hits	863	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

RREB1_HUMAN
NC score	0.007922 (rank : 291)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	267	Target Neighborhood Hits	879	Shared Neighborhood Hits	37
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

CDX2_MOUSE
NC score	0.007461 (rank : 292)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	267	Target Neighborhood Hits	336	Shared Neighborhood Hits	8
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

BCL6_MOUSE
NC score	0.007107 (rank : 293)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	267	Target Neighborhood Hits	913	Shared Neighborhood Hits	45
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

PCD15_HUMAN
NC score	0.007000 (rank : 294)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	267	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
NC score	0.006860 (rank : 295)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	267	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

M4K1_HUMAN
NC score	0.006729 (rank : 296)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	267	Target Neighborhood Hits	884	Shared Neighborhood Hits	24
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

KLF11_MOUSE
NC score	0.006588 (rank : 297)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	267	Target Neighborhood Hits	714	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

BCL6_HUMAN
NC score	0.005823 (rank : 298)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	267	Target Neighborhood Hits	922	Shared Neighborhood Hits	43
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

RAF1_MOUSE
NC score	0.005113 (rank : 299)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	267	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

MAGAC_HUMAN
NC score	0.004876 (rank : 300)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	267	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P43365, Q9NSD3	Gene names	MAGEA12, MAGE12
Domain Architecture
Description	Melanoma-associated antigen 12 (MAGE-12 antigen) (MAGE12F).

TESK1_MOUSE
NC score	0.004814 (rank : 301)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	267	Target Neighborhood Hits	862	Shared Neighborhood Hits	24
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

PTPRF_HUMAN
NC score	0.003772 (rank : 302)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	267	Target Neighborhood Hits	489	Shared Neighborhood Hits	6
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

ZBT40_HUMAN
NC score	0.002368 (rank : 303)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	267	Target Neighborhood Hits	949	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

OPN4_HUMAN
NC score	-0.001718 (rank : 304)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	267	Target Neighborhood Hits	923	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHM6, Q2PP22, Q8NGQ9	Gene names	OPN4, MOP
Domain Architecture
Description	Melanopsin (Opsin-4).