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Network neighborhood for query Sequence : RBP2_HUMAN

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RBP2_HUMAN
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RBP22_HUMAN
θ value	0 (rank : 1)	NC score	0.684212 (rank : 19)
Query Neighborhood Hits	249	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RBP26_HUMAN
θ value	0 (rank : 2)	NC score	0.687030 (rank : 17)
Query Neighborhood Hits	249	Target Neighborhood Hits	146	Shared Neighborhood Hits	49
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RBP2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	249	Target Neighborhood Hits	249	Shared Neighborhood Hits	249
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RBP2_MOUSE
θ value	0 (rank : 4)	NC score	0.984947 (rank : 2)
Query Neighborhood Hits	249	Target Neighborhood Hits	232	Shared Neighborhood Hits	119
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RGPD8_HUMAN
θ value	0 (rank : 5)	NC score	0.685101 (rank : 18)
Query Neighborhood Hits	249	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

PPIA_HUMAN
θ value	6.32992e-62 (rank : 6)	NC score	0.754508 (rank : 5)
Query Neighborhood Hits	249	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIF_MOUSE
θ value	6.32992e-62 (rank : 7)	NC score	0.755283 (rank : 3)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIA_MOUSE
θ value	1.84173e-61 (rank : 8)	NC score	0.754530 (rank : 4)
Query Neighborhood Hits	249	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIF_HUMAN
θ value	2.40537e-61 (rank : 9)	NC score	0.753609 (rank : 6)
Query Neighborhood Hits	249	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIE_HUMAN
θ value	8.28633e-54 (rank : 10)	NC score	0.641317 (rank : 27)
Query Neighborhood Hits	249	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNP9, O43634, O43635, Q5TGA0, Q9UIZ5	Gene names	PPIE, CYP33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPIE_MOUSE
θ value	8.28633e-54 (rank : 11)	NC score	0.641208 (rank : 28)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZH3, Q9D8C0	Gene names	Ppie, Cyp33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPID_MOUSE
θ value	3.37202e-47 (rank : 12)	NC score	0.671744 (rank : 20)
Query Neighborhood Hits	249	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PPID_HUMAN
θ value	1.28137e-46 (rank : 13)	NC score	0.669439 (rank : 21)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

PPIB_HUMAN
θ value	7.03111e-45 (rank : 14)	NC score	0.738545 (rank : 9)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P23284, Q9BVK5	Gene names	PPIB, CYPB
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIB_MOUSE
θ value	2.04573e-44 (rank : 15)	NC score	0.738103 (rank : 10)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P24369	Gene names	Ppib
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

NU153_HUMAN
θ value	2.67181e-44 (rank : 16)	NC score	0.393938 (rank : 35)
Query Neighborhood Hits	249	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PPIC_MOUSE
θ value	5.03882e-43 (rank : 17)	NC score	0.737629 (rank : 11)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P30412	Gene names	Ppic, Cypc
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIH_HUMAN
θ value	1.46607e-42 (rank : 18)	NC score	0.740447 (rank : 7)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	O43447	Gene names	PPIH, CYP20, CYPH
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH).

RANG_MOUSE
θ value	3.26607e-42 (rank : 19)	NC score	0.653299 (rank : 25)
Query Neighborhood Hits	249	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
θ value	4.2656e-42 (rank : 20)	NC score	0.648644 (rank : 26)
Query Neighborhood Hits	249	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

PPIH_MOUSE
θ value	1.62093e-41 (rank : 21)	NC score	0.740363 (rank : 8)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D868, Q9CQU7	Gene names	Ppih
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H).

PPIC_HUMAN
θ value	2.11701e-41 (rank : 22)	NC score	0.737350 (rank : 12)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P45877	Gene names	PPIC, CYPC
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIG_HUMAN
θ value	1.05066e-40 (rank : 23)	NC score	0.616422 (rank : 32)
Query Neighborhood Hits	249	Target Neighborhood Hits	670	Shared Neighborhood Hits	55
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

NKTR_HUMAN
θ value	1.42001e-37 (rank : 24)	NC score	0.629340 (rank : 29)
Query Neighborhood Hits	249	Target Neighborhood Hits	658	Shared Neighborhood Hits	60
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NKTR_MOUSE
θ value	1.42001e-37 (rank : 25)	NC score	0.657120 (rank : 24)
Query Neighborhood Hits	249	Target Neighborhood Hits	417	Shared Neighborhood Hits	46
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPIL2_MOUSE
θ value	1.80048e-24 (rank : 26)	NC score	0.660428 (rank : 22)
Query Neighborhood Hits	249	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

PPIL3_HUMAN
θ value	6.84181e-24 (rank : 27)	NC score	0.692285 (rank : 15)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2H8, Q86WF9, Q96IA9, Q9BXZ1	Gene names	PPIL3
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (Cyclophilin J) (CyPJ).

PPIL2_HUMAN
θ value	1.16704e-23 (rank : 28)	NC score	0.659007 (rank : 23)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q13356, Q13357, Q8TAH2, Q9BWR8	Gene names	PPIL2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

PPIL3_MOUSE
θ value	4.43474e-23 (rank : 29)	NC score	0.690786 (rank : 16)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D6L8, Q812D2, Q9CY23	Gene names	Ppil3, Cyp10l
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (CYP10L).

PPIL1_HUMAN
θ value	2.20094e-22 (rank : 30)	NC score	0.698615 (rank : 14)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3C6, O15001	Gene names	PPIL1, CYPL1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8) (PPIase) (Rotamase).

PPIL1_MOUSE
θ value	2.20094e-22 (rank : 31)	NC score	0.698638 (rank : 13)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D0W5, Q3UA03	Gene names	Ppil1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8) (PPIase) (Rotamase).

PPWD1_MOUSE
θ value	2.69047e-20 (rank : 32)	NC score	0.623515 (rank : 30)
Query Neighborhood Hits	249	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_HUMAN
θ value	4.58923e-20 (rank : 33)	NC score	0.621677 (rank : 31)
Query Neighborhood Hits	249	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPIL4_MOUSE
θ value	1.29331e-14 (rank : 34)	NC score	0.514074 (rank : 33)
Query Neighborhood Hits	249	Target Neighborhood Hits	232	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CXG3, Q3TJX1, Q68FC7, Q9CT22	Gene names	Ppil4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

PPIL4_HUMAN
θ value	1.68911e-14 (rank : 35)	NC score	0.511023 (rank : 34)
Query Neighborhood Hits	249	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

RNF31_HUMAN
θ value	1.25267e-09 (rank : 36)	NC score	0.165524 (rank : 39)
Query Neighborhood Hits	249	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

ZRAN1_HUMAN
θ value	1.25267e-09 (rank : 37)	NC score	0.191855 (rank : 38)
Query Neighborhood Hits	249	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

RNF31_MOUSE
θ value	2.79066e-09 (rank : 38)	NC score	0.157077 (rank : 40)
Query Neighborhood Hits	249	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RANB3_HUMAN
θ value	1.43324e-05 (rank : 39)	NC score	0.240532 (rank : 36)
Query Neighborhood Hits	249	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RANB3_MOUSE
θ value	1.87187e-05 (rank : 40)	NC score	0.233073 (rank : 37)
Query Neighborhood Hits	249	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

NEIL3_HUMAN
θ value	0.000158464 (rank : 41)	NC score	0.096930 (rank : 47)
Query Neighborhood Hits	249	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

CO039_MOUSE
θ value	0.00509761 (rank : 42)	NC score	0.042453 (rank : 74)
Query Neighborhood Hits	249	Target Neighborhood Hits	445	Shared Neighborhood Hits	34
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

NU214_HUMAN
θ value	0.00509761 (rank : 43)	NC score	0.081527 (rank : 55)
Query Neighborhood Hits	249	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

LYAM2_HUMAN
θ value	0.00665767 (rank : 44)	NC score	0.014806 (rank : 149)
Query Neighborhood Hits	249	Target Neighborhood Hits	394	Shared Neighborhood Hits	8
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

YAF2_HUMAN
θ value	0.00665767 (rank : 45)	NC score	0.129869 (rank : 42)
Query Neighborhood Hits	249	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

YAF2_MOUSE
θ value	0.00665767 (rank : 46)	NC score	0.132293 (rank : 41)
Query Neighborhood Hits	249	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

NEIL3_MOUSE
θ value	0.00869519 (rank : 47)	NC score	0.090181 (rank : 52)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

MAGE1_HUMAN
θ value	0.0113563 (rank : 48)	NC score	0.028558 (rank : 100)
Query Neighborhood Hits	249	Target Neighborhood Hits	1389	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NUP50_MOUSE
θ value	0.0113563 (rank : 49)	NC score	0.092564 (rank : 51)
Query Neighborhood Hits	249	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIH2, Q9CU02, Q9JK85	Gene names	Nup50, Npap60
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

SC24A_MOUSE
θ value	0.0113563 (rank : 50)	NC score	0.035148 (rank : 86)
Query Neighborhood Hits	249	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SYCP1_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.029407 (rank : 96)
Query Neighborhood Hits	249	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CDC27_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.117324 (rank : 45)
Query Neighborhood Hits	249	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

MNAB_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.036622 (rank : 82)
Query Neighborhood Hits	249	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MLKL_MOUSE
θ value	0.0252991 (rank : 54)	NC score	0.020703 (rank : 126)
Query Neighborhood Hits	249	Target Neighborhood Hits	707	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

RYBP_HUMAN
θ value	0.0252991 (rank : 55)	NC score	0.125651 (rank : 43)
Query Neighborhood Hits	249	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

RYBP_MOUSE
θ value	0.0252991 (rank : 56)	NC score	0.118859 (rank : 44)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

ZRAB2_HUMAN
θ value	0.0252991 (rank : 57)	NC score	0.093259 (rank : 50)
Query Neighborhood Hits	249	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

DOT1L_HUMAN
θ value	0.0330416 (rank : 58)	NC score	0.038714 (rank : 81)
Query Neighborhood Hits	249	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

BBS4_HUMAN
θ value	0.0431538 (rank : 59)	NC score	0.099118 (rank : 46)
Query Neighborhood Hits	249	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

FHL1_HUMAN
θ value	0.0431538 (rank : 60)	NC score	0.012505 (rank : 166)
Query Neighborhood Hits	249	Target Neighborhood Hits	436	Shared Neighborhood Hits	6
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

PEX5_HUMAN
θ value	0.0431538 (rank : 61)	NC score	0.089115 (rank : 53)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

ATN1_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.047739 (rank : 69)
Query Neighborhood Hits	249	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

OGT1_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.073004 (rank : 62)
Query Neighborhood Hits	249	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

PEX5_MOUSE
θ value	0.0961366 (rank : 64)	NC score	0.074548 (rank : 61)
Query Neighborhood Hits	249	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

CD2AP_MOUSE
θ value	0.125558 (rank : 65)	NC score	0.016180 (rank : 141)
Query Neighborhood Hits	249	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

HORN_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.029957 (rank : 94)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

IFT88_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.081264 (rank : 56)
Query Neighborhood Hits	249	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

MBD6_HUMAN
θ value	0.163984 (rank : 68)	NC score	0.033905 (rank : 87)
Query Neighborhood Hits	249	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MNAB_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.030489 (rank : 93)
Query Neighborhood Hits	249	Target Neighborhood Hits	231	Shared Neighborhood Hits	9
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PTN23_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.013615 (rank : 158)
Query Neighborhood Hits	249	Target Neighborhood Hits	726	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

ZEP2_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.006780 (rank : 205)
Query Neighborhood Hits	249	Target Neighborhood Hits	937	Shared Neighborhood Hits	28
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

ZNF77_HUMAN
θ value	0.163984 (rank : 72)	NC score	-0.002693 (rank : 248)
Query Neighborhood Hits	249	Target Neighborhood Hits	759	Shared Neighborhood Hits	13
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

NFAT5_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.018863 (rank : 129)
Query Neighborhood Hits	249	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NOLC1_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.032491 (rank : 89)
Query Neighborhood Hits	249	Target Neighborhood Hits	452	Shared Neighborhood Hits	22
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TNKS1_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.006405 (rank : 208)
Query Neighborhood Hits	249	Target Neighborhood Hits	477	Shared Neighborhood Hits	21
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

CDC23_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.094716 (rank : 49)
Query Neighborhood Hits	249	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CDC23_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.095312 (rank : 48)
Query Neighborhood Hits	249	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

PGCA_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.015570 (rank : 143)
Query Neighborhood Hits	249	Target Neighborhood Hits	643	Shared Neighborhood Hits	25
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PLXC1_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.010954 (rank : 179)
Query Neighborhood Hits	249	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

TCGAP_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.014738 (rank : 150)
Query Neighborhood Hits	249	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ARI1A_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.031333 (rank : 90)
Query Neighborhood Hits	249	Target Neighborhood Hits	787	Shared Neighborhood Hits	45
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BBS4_MOUSE
θ value	0.365318 (rank : 82)	NC score	0.079344 (rank : 59)
Query Neighborhood Hits	249	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

FIBA_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.009310 (rank : 188)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

KLF17_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.002524 (rank : 229)
Query Neighborhood Hits	249	Target Neighborhood Hits	882	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

MYH3_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.008800 (rank : 191)
Query Neighborhood Hits	249	Target Neighborhood Hits	1660	Shared Neighborhood Hits	38
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PO121_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.056463 (rank : 65)
Query Neighborhood Hits	249	Target Neighborhood Hits	344	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SOX3_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.013131 (rank : 161)
Query Neighborhood Hits	249	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_MOUSE
θ value	0.365318 (rank : 88)	NC score	0.012926 (rank : 163)
Query Neighborhood Hits	249	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

BRD4_MOUSE
θ value	0.47712 (rank : 89)	NC score	0.017750 (rank : 135)
Query Neighborhood Hits	249	Target Neighborhood Hits	845	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

GLI1_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.000641 (rank : 238)
Query Neighborhood Hits	249	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

JIP4_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.042746 (rank : 73)
Query Neighborhood Hits	249	Target Neighborhood Hits	593	Shared Neighborhood Hits	26
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KU70_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.040062 (rank : 78)
Query Neighborhood Hits	249	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P12956, Q9UCQ2, Q9UCQ3	Gene names	XRCC6, G22P1
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.1.-) (ATP-dependent DNA helicase II 70 kDa subunit) (Lupus Ku autoantigen protein p70) (Ku70) (70 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA-repair protein XRCC6).

LIPB1_HUMAN
θ value	0.47712 (rank : 93)	NC score	0.014202 (rank : 153)
Query Neighborhood Hits	249	Target Neighborhood Hits	640	Shared Neighborhood Hits	17
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

DEN1A_HUMAN
θ value	0.62314 (rank : 94)	NC score	0.022595 (rank : 119)
Query Neighborhood Hits	249	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

JIP4_HUMAN
θ value	0.62314 (rank : 95)	NC score	0.040571 (rank : 77)
Query Neighborhood Hits	249	Target Neighborhood Hits	585	Shared Neighborhood Hits	24
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

BRPF3_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.018411 (rank : 133)
Query Neighborhood Hits	249	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CMTA2_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.027561 (rank : 105)
Query Neighborhood Hits	249	Target Neighborhood Hits	199	Shared Neighborhood Hits	9
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DEN1A_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.020715 (rank : 125)
Query Neighborhood Hits	249	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

EVI2B_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.026384 (rank : 107)
Query Neighborhood Hits	249	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

TAB2_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.043214 (rank : 71)
Query Neighborhood Hits	249	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TAB3_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.042271 (rank : 76)
Query Neighborhood Hits	249	Target Neighborhood Hits	273	Shared Neighborhood Hits	35
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ACK1_MOUSE
θ value	1.06291 (rank : 102)	NC score	-0.001750 (rank : 245)
Query Neighborhood Hits	249	Target Neighborhood Hits	1080	Shared Neighborhood Hits	24
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ARI1B_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.027869 (rank : 103)
Query Neighborhood Hits	249	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

CNTRB_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.010444 (rank : 182)
Query Neighborhood Hits	249	Target Neighborhood Hits	1029	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ETV5_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.015202 (rank : 146)
Query Neighborhood Hits	249	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

IL4RA_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.036114 (rank : 85)
Query Neighborhood Hits	249	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

NUP50_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.057614 (rank : 63)
Query Neighborhood Hits	249	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKX7, O75644, Q9NPM9, Q9NPR6, Q9P1K5	Gene names	NUP50, NPAP60L
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

SYCP1_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.012978 (rank : 162)
Query Neighborhood Hits	249	Target Neighborhood Hits	1313	Shared Neighborhood Hits	38
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TCOF_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.024933 (rank : 110)
Query Neighborhood Hits	249	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CN032_HUMAN
θ value	1.38821 (rank : 110)	NC score	0.024420 (rank : 112)
Query Neighborhood Hits	249	Target Neighborhood Hits	267	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

K0372_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.056585 (rank : 64)
Query Neighborhood Hits	249	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

RERE_MOUSE
θ value	1.38821 (rank : 112)	NC score	0.021649 (rank : 122)
Query Neighborhood Hits	249	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SCUB3_MOUSE
θ value	1.38821 (rank : 113)	NC score	0.003341 (rank : 224)
Query Neighborhood Hits	249	Target Neighborhood Hits	442	Shared Neighborhood Hits	7
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SOS1_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.009440 (rank : 186)
Query Neighborhood Hits	249	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SRBP1_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.013686 (rank : 156)
Query Neighborhood Hits	249	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SYG_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.036152 (rank : 84)
Query Neighborhood Hits	249	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P41250, Q969Y1	Gene names	GARS
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

ZBT38_HUMAN
θ value	1.38821 (rank : 117)	NC score	-0.001622 (rank : 244)
Query Neighborhood Hits	249	Target Neighborhood Hits	885	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

AP3B1_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.022767 (rank : 118)
Query Neighborhood Hits	249	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DBPA_MOUSE
θ value	1.81305 (rank : 119)	NC score	0.015260 (rank : 145)
Query Neighborhood Hits	249	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

HDGR3_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.025260 (rank : 109)
Query Neighborhood Hits	249	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HSF1_MOUSE
θ value	1.81305 (rank : 121)	NC score	0.019959 (rank : 127)
Query Neighborhood Hits	249	Target Neighborhood Hits	267	Shared Neighborhood Hits	22
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

LIPB1_MOUSE
θ value	1.81305 (rank : 122)	NC score	0.011736 (rank : 173)
Query Neighborhood Hits	249	Target Neighborhood Hits	727	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

PHF14_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.023658 (rank : 115)
Query Neighborhood Hits	249	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	1.81305 (rank : 124)	NC score	0.022321 (rank : 121)
Query Neighborhood Hits	249	Target Neighborhood Hits	342	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PRG4_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.011231 (rank : 176)
Query Neighborhood Hits	249	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RUFY1_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.014614 (rank : 152)
Query Neighborhood Hits	249	Target Neighborhood Hits	848	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

TRIPB_HUMAN
θ value	1.81305 (rank : 127)	NC score	0.011702 (rank : 174)
Query Neighborhood Hits	249	Target Neighborhood Hits	1587	Shared Neighborhood Hits	46
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

WASIP_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.027738 (rank : 104)
Query Neighborhood Hits	249	Target Neighborhood Hits	392	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

DSPP_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.051147 (rank : 68)
Query Neighborhood Hits	249	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ETV1_HUMAN
θ value	2.36792 (rank : 130)	NC score	0.010831 (rank : 181)
Query Neighborhood Hits	249	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

II2A_MOUSE
θ value	2.36792 (rank : 131)	NC score	0.030667 (rank : 92)
Query Neighborhood Hits	249	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P15091	Gene names	Ifi202a, Ifi202
Domain Architecture
Description	Interferon-activable protein 202a (Ifi-202a) (Interferon-inducible protein p202a).

II2B_MOUSE
θ value	2.36792 (rank : 132)	NC score	0.031098 (rank : 91)
Query Neighborhood Hits	249	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R002	Gene names	Ifi202b
Domain Architecture
Description	Interferon-activable protein 202b (Ifi-202b) (Interferon-inducible protein p202b).

K1543_MOUSE
θ value	2.36792 (rank : 133)	NC score	0.025450 (rank : 108)
Query Neighborhood Hits	249	Target Neighborhood Hits	497	Shared Neighborhood Hits	34
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

KPCG_HUMAN
θ value	2.36792 (rank : 134)	NC score	-0.004750 (rank : 250)
Query Neighborhood Hits	249	Target Neighborhood Hits	1126	Shared Neighborhood Hits	8
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PHF3_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.024872 (rank : 111)
Query Neighborhood Hits	249	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PO121_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.047405 (rank : 70)
Query Neighborhood Hits	249	Target Neighborhood Hits	345	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SC24C_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.028054 (rank : 102)
Query Neighborhood Hits	249	Target Neighborhood Hits	662	Shared Neighborhood Hits	50
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SCUB3_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.003050 (rank : 226)
Query Neighborhood Hits	249	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

WNK4_HUMAN
θ value	2.36792 (rank : 139)	NC score	-0.002075 (rank : 247)
Query Neighborhood Hits	249	Target Neighborhood Hits	1043	Shared Neighborhood Hits	20
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZF106_MOUSE
θ value	2.36792 (rank : 140)	NC score	0.009384 (rank : 187)
Query Neighborhood Hits	249	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

ZFY19_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.012302 (rank : 169)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

CIR_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.084773 (rank : 54)
Query Neighborhood Hits	249	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CMTA2_MOUSE
θ value	3.0926 (rank : 143)	NC score	0.021420 (rank : 124)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CV106_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.024084 (rank : 114)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

ETV1_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.010395 (rank : 183)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

IRS2_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.012360 (rank : 168)
Query Neighborhood Hits	249	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IRX5_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.007918 (rank : 196)
Query Neighborhood Hits	249	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

KIF17_HUMAN
θ value	3.0926 (rank : 148)	NC score	0.008166 (rank : 193)
Query Neighborhood Hits	249	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LDB3_MOUSE
θ value	3.0926 (rank : 149)	NC score	0.018712 (rank : 130)
Query Neighborhood Hits	249	Target Neighborhood Hits	510	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MLL2_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.016192 (rank : 140)
Query Neighborhood Hits	249	Target Neighborhood Hits	1788	Shared Neighborhood Hits	73
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MSH4_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.008473 (rank : 192)
Query Neighborhood Hits	249	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

MUC13_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.021422 (rank : 123)
Query Neighborhood Hits	249	Target Neighborhood Hits	447	Shared Neighborhood Hits	15
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NPDC1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.015475 (rank : 144)
Query Neighborhood Hits	249	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQX5, Q9BTD6, Q9BXT3, Q9NQS2, Q9Y434	Gene names	NPDC1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

CD2AP_HUMAN
θ value	4.03905 (rank : 154)	NC score	0.010217 (rank : 184)
Query Neighborhood Hits	249	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CELR1_MOUSE
θ value	4.03905 (rank : 155)	NC score	-0.002031 (rank : 246)
Query Neighborhood Hits	249	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CF152_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.017907 (rank : 134)
Query Neighborhood Hits	249	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CI093_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.010845 (rank : 180)
Query Neighborhood Hits	249	Target Neighborhood Hits	1088	Shared Neighborhood Hits	36
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

DAXX_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.017735 (rank : 136)
Query Neighborhood Hits	249	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

LRC40_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.008076 (rank : 194)
Query Neighborhood Hits	249	Target Neighborhood Hits	313	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

MAGC1_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.015149 (rank : 147)
Query Neighborhood Hits	249	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PADI3_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.005102 (rank : 216)
Query Neighborhood Hits	249	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).

RAI14_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.003181 (rank : 225)
Query Neighborhood Hits	249	Target Neighborhood Hits	1505	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RBM5_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.029103 (rank : 97)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	P52756, Q93021, Q9BU14, Q9UKY8, Q9UL24	Gene names	RBM5
Domain Architecture
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15) (Protein G15) (NY-REN-9 antigen).

RBM5_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.029468 (rank : 95)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

SGOL2_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.012250 (rank : 170)
Query Neighborhood Hits	249	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SHAN1_HUMAN
θ value	4.03905 (rank : 166)	NC score	0.006315 (rank : 209)
Query Neighborhood Hits	249	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TAB2_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.036527 (rank : 83)
Query Neighborhood Hits	249	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TTC12_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.043090 (rank : 72)
Query Neighborhood Hits	249	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

ZEP2_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.004251 (rank : 221)
Query Neighborhood Hits	249	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

ZFHX2_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.002396 (rank : 231)
Query Neighborhood Hits	249	Target Neighborhood Hits	1178	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

A4_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.007065 (rank : 203)
Query Neighborhood Hits	249	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

BRDT_MOUSE
θ value	5.27518 (rank : 172)	NC score	0.011039 (rank : 178)
Query Neighborhood Hits	249	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CH076_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.011137 (rank : 177)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K31, Q53HC1	Gene names	C8orf76
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf76.

CSN2_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.017522 (rank : 138)
Query Neighborhood Hits	249	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.017522 (rank : 139)
Query Neighborhood Hits	249	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

DBPA_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.011917 (rank : 172)
Query Neighborhood Hits	249	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	P16989, Q14121, Q969N6	Gene names	CSDA, DBPA
Domain Architecture
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Single-strand DNA-binding protein NF-GMB).

GREM1_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.012562 (rank : 164)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

GREM1_MOUSE
θ value	5.27518 (rank : 178)	NC score	0.012507 (rank : 165)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

IFIT1_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.019457 (rank : 128)
Query Neighborhood Hits	249	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

IQEC3_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.004531 (rank : 218)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

MUCDL_MOUSE
θ value	5.27518 (rank : 181)	NC score	0.013381 (rank : 159)
Query Neighborhood Hits	249	Target Neighborhood Hits	461	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NCA11_MOUSE
θ value	5.27518 (rank : 182)	NC score	0.000826 (rank : 237)
Query Neighborhood Hits	249	Target Neighborhood Hits	661	Shared Neighborhood Hits	16
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NEUM_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.011308 (rank : 175)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

RNPS1_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.053693 (rank : 66)
Query Neighborhood Hits	249	Target Neighborhood Hits	285	Shared Neighborhood Hits	16
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.053693 (rank : 67)
Query Neighborhood Hits	249	Target Neighborhood Hits	285	Shared Neighborhood Hits	16
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

RPGR_MOUSE
θ value	5.27518 (rank : 186)	NC score	0.007224 (rank : 202)
Query Neighborhood Hits	249	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

S4A4_MOUSE
θ value	5.27518 (rank : 187)	NC score	0.007948 (rank : 195)
Query Neighborhood Hits	249	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

SFPQ_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.014615 (rank : 151)
Query Neighborhood Hits	249	Target Neighborhood Hits	986	Shared Neighborhood Hits	49
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SIGL5_MOUSE
θ value	5.27518 (rank : 189)	NC score	0.002114 (rank : 232)
Query Neighborhood Hits	249	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SUHW4_MOUSE
θ value	5.27518 (rank : 190)	NC score	-0.000056 (rank : 242)
Query Neighborhood Hits	249	Target Neighborhood Hits	737	Shared Neighborhood Hits	15
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

TAXB1_HUMAN
θ value	5.27518 (rank : 191)	NC score	0.007689 (rank : 197)
Query Neighborhood Hits	249	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TIM44_MOUSE
θ value	5.27518 (rank : 192)	NC score	0.022572 (rank : 120)
Query Neighborhood Hits	249	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TREF1_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.006047 (rank : 211)
Query Neighborhood Hits	249	Target Neighborhood Hits	651	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TRPV1_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.003626 (rank : 223)
Query Neighborhood Hits	249	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TTC12_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.039305 (rank : 80)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

AMOL2_MOUSE
θ value	6.88961 (rank : 196)	NC score	0.005076 (rank : 217)
Query Neighborhood Hits	249	Target Neighborhood Hits	591	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ARMX2_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.007628 (rank : 198)
Query Neighborhood Hits	249	Target Neighborhood Hits	349	Shared Neighborhood Hits	25
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

ATBF1_MOUSE
θ value	6.88961 (rank : 198)	NC score	0.001424 (rank : 235)
Query Neighborhood Hits	249	Target Neighborhood Hits	1841	Shared Neighborhood Hits	53
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CF146_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.013660 (rank : 157)
Query Neighborhood Hits	249	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXS0, Q5JYK1	Gene names	C6orf146
Domain Architecture	No domain graphic available
Description	Protein C6orf146.

CYLD_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.017532 (rank : 137)
Query Neighborhood Hits	249	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

DGKI_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.001401 (rank : 236)
Query Neighborhood Hits	249	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

ELOA1_MOUSE
θ value	6.88961 (rank : 202)	NC score	0.013840 (rank : 154)
Query Neighborhood Hits	249	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

GCC2_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.076230 (rank : 60)
Query Neighborhood Hits	249	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GRLF1_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.004189 (rank : 222)
Query Neighborhood Hits	249	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

MCM3A_HUMAN
θ value	6.88961 (rank : 205)	NC score	0.013825 (rank : 155)
Query Neighborhood Hits	249	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

MFN1_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.013308 (rank : 160)
Query Neighborhood Hits	249	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

MLL3_MOUSE
θ value	6.88961 (rank : 207)	NC score	0.016076 (rank : 142)
Query Neighborhood Hits	249	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MUC2_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.009263 (rank : 189)
Query Neighborhood Hits	249	Target Neighborhood Hits	906	Shared Neighborhood Hits	40
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYH4_HUMAN
θ value	6.88961 (rank : 209)	NC score	0.004285 (rank : 220)
Query Neighborhood Hits	249	Target Neighborhood Hits	1377	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

P80C_HUMAN
θ value	6.88961 (rank : 210)	NC score	0.032611 (rank : 88)
Query Neighborhood Hits	249	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

RBX2_HUMAN
θ value	6.88961 (rank : 211)	NC score	0.007299 (rank : 201)
Query Neighborhood Hits	249	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RENT1_MOUSE
θ value	6.88961 (rank : 212)	NC score	0.004433 (rank : 219)
Query Neighborhood Hits	249	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RPTN_MOUSE
θ value	6.88961 (rank : 213)	NC score	0.028741 (rank : 99)
Query Neighborhood Hits	249	Target Neighborhood Hits	650	Shared Neighborhood Hits	36
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

S4A4_HUMAN
θ value	6.88961 (rank : 214)	NC score	0.007531 (rank : 200)
Query Neighborhood Hits	249	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

SPT5H_HUMAN
θ value	6.88961 (rank : 215)	NC score	0.028171 (rank : 101)
Query Neighborhood Hits	249	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	6.88961 (rank : 216)	NC score	0.029078 (rank : 98)
Query Neighborhood Hits	249	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SYTL5_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.006501 (rank : 207)
Query Neighborhood Hits	249	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TIP60_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.006559 (rank : 206)
Query Neighborhood Hits	249	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

5HT5A_MOUSE
θ value	8.99809 (rank : 219)	NC score	-0.000584 (rank : 243)
Query Neighborhood Hits	249	Target Neighborhood Hits	615	Shared Neighborhood Hits	6
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

AT1A3_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.001548 (rank : 234)
Query Neighborhood Hits	249	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P13637, Q16732, Q16735, Q969K5	Gene names	ATP1A3
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

AT1A3_MOUSE
θ value	8.99809 (rank : 221)	NC score	0.001551 (rank : 233)
Query Neighborhood Hits	249	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIC6	Gene names	Atp1a3
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

ATOH1_MOUSE
θ value	8.99809 (rank : 222)	NC score	0.003018 (rank : 227)
Query Neighborhood Hits	249	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

BCAR1_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.009912 (rank : 185)
Query Neighborhood Hits	249	Target Neighborhood Hits	554	Shared Neighborhood Hits	33
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

CBP_HUMAN
θ value	8.99809 (rank : 224)	NC score	0.012009 (rank : 171)
Query Neighborhood Hits	249	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CLC4F_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.027065 (rank : 106)
Query Neighborhood Hits	249	Target Neighborhood Hits	513	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

CO4A1_HUMAN
θ value	8.99809 (rank : 226)	NC score	0.000481 (rank : 239)
Query Neighborhood Hits	249	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

DCR1A_MOUSE
θ value	8.99809 (rank : 227)	NC score	0.005410 (rank : 215)
Query Neighborhood Hits	249	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

DMD_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.002411 (rank : 230)
Query Neighborhood Hits	249	Target Neighborhood Hits	1111	Shared Neighborhood Hits	27
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DSPP_MOUSE
θ value	8.99809 (rank : 229)	NC score	0.039589 (rank : 79)
Query Neighborhood Hits	249	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FOXGA_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.000219 (rank : 240)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

GEPH_HUMAN
θ value	8.99809 (rank : 231)	NC score	0.009178 (rank : 190)
Query Neighborhood Hits	249	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQX3, Q9P2G2	Gene names	GPHN, GPH, KIAA1385
Domain Architecture
Description	Gephyrin.

GIT2_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.002776 (rank : 228)
Query Neighborhood Hits	249	Target Neighborhood Hits	381	Shared Neighborhood Hits	17
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

HDGR3_MOUSE
θ value	8.99809 (rank : 233)	NC score	0.024323 (rank : 113)
Query Neighborhood Hits	249	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

HNRL1_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.005665 (rank : 214)
Query Neighborhood Hits	249	Target Neighborhood Hits	173	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

IFT88_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.042400 (rank : 75)
Query Neighborhood Hits	249	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

IRX5_MOUSE
θ value	8.99809 (rank : 236)	NC score	0.006016 (rank : 212)
Query Neighborhood Hits	249	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

MAP1B_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.014881 (rank : 148)
Query Neighborhood Hits	249	Target Neighborhood Hits	903	Shared Neighborhood Hits	49
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MAST1_HUMAN
θ value	8.99809 (rank : 238)	NC score	-0.004104 (rank : 249)
Query Neighborhood Hits	249	Target Neighborhood Hits	1146	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PABP1_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.022768 (rank : 117)
Query Neighborhood Hits	249	Target Neighborhood Hits	269	Shared Neighborhood Hits	12
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	8.99809 (rank : 240)	NC score	0.023079 (rank : 116)
Query Neighborhood Hits	249	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PRGC1_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.012446 (rank : 167)
Query Neighborhood Hits	249	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

RBM6_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.018602 (rank : 131)
Query Neighborhood Hits	249	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SFR15_HUMAN
θ value	8.99809 (rank : 243)	NC score	0.018547 (rank : 132)
Query Neighborhood Hits	249	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SOS1_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.006976 (rank : 204)
Query Neighborhood Hits	249	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SUHW4_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.000134 (rank : 241)
Query Neighborhood Hits	249	Target Neighborhood Hits	860	Shared Neighborhood Hits	22
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

SYNP2_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.006255 (rank : 210)
Query Neighborhood Hits	249	Target Neighborhood Hits	323	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TIP60_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.005912 (rank : 213)
Query Neighborhood Hits	249	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TITIN_HUMAN
θ value	8.99809 (rank : 248)	NC score	-0.005751 (rank : 251)
Query Neighborhood Hits	249	Target Neighborhood Hits	2923	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI66_MOUSE
θ value	8.99809 (rank : 249)	NC score	0.007614 (rank : 199)
Query Neighborhood Hits	249	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

GCC2_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.080830 (rank : 58)
Query Neighborhood Hits	249	Target Neighborhood Hits	1558	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.080982 (rank : 57)
Query Neighborhood Hits	249	Target Neighborhood Hits	1559	Shared Neighborhood Hits	41
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

Hits sorted by NC score

RBP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	249	Target Neighborhood Hits	249	Shared Neighborhood Hits	249
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

RBP2_MOUSE
NC score	0.984947 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	249	Target Neighborhood Hits	232	Shared Neighborhood Hits	119
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

PPIF_MOUSE
NC score	0.755283 (rank : 3)	θ value	6.32992e-62 (rank : 7)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIA_MOUSE
NC score	0.754530 (rank : 4)	θ value	1.84173e-61 (rank : 8)
Query Neighborhood Hits	249	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIA_HUMAN
NC score	0.754508 (rank : 5)	θ value	6.32992e-62 (rank : 6)
Query Neighborhood Hits	249	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIF_HUMAN
NC score	0.753609 (rank : 6)	θ value	2.40537e-61 (rank : 9)
Query Neighborhood Hits	249	Target Neighborhood Hits	30	Shared Neighborhood Hits	29
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIH_HUMAN
NC score	0.740447 (rank : 7)	θ value	1.46607e-42 (rank : 18)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	O43447	Gene names	PPIH, CYP20, CYPH
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH).

PPIH_MOUSE
NC score	0.740363 (rank : 8)	θ value	1.62093e-41 (rank : 21)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D868, Q9CQU7	Gene names	Ppih
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H).

PPIB_HUMAN
NC score	0.738545 (rank : 9)	θ value	7.03111e-45 (rank : 14)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P23284, Q9BVK5	Gene names	PPIB, CYPB
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIB_MOUSE
NC score	0.738103 (rank : 10)	θ value	2.04573e-44 (rank : 15)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P24369	Gene names	Ppib
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIC_MOUSE
NC score	0.737629 (rank : 11)	θ value	5.03882e-43 (rank : 17)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P30412	Gene names	Ppic, Cypc
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIC_HUMAN
NC score	0.737350 (rank : 12)	θ value	2.11701e-41 (rank : 22)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	P45877	Gene names	PPIC, CYPC
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIL1_MOUSE
NC score	0.698638 (rank : 13)	θ value	2.20094e-22 (rank : 31)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D0W5, Q3UA03	Gene names	Ppil1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8) (PPIase) (Rotamase).

PPIL1_HUMAN
NC score	0.698615 (rank : 14)	θ value	2.20094e-22 (rank : 30)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3C6, O15001	Gene names	PPIL1, CYPL1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 1 (EC 5.2.1.8) (PPIase) (Rotamase).

PPIL3_HUMAN
NC score	0.692285 (rank : 15)	θ value	6.84181e-24 (rank : 27)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2H8, Q86WF9, Q96IA9, Q9BXZ1	Gene names	PPIL3
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (Cyclophilin J) (CyPJ).

PPIL3_MOUSE
NC score	0.690786 (rank : 16)	θ value	4.43474e-23 (rank : 29)
Query Neighborhood Hits	249	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D6L8, Q812D2, Q9CY23	Gene names	Ppil3, Cyp10l
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 3 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL3) (CYP10L).

RBP26_HUMAN
NC score	0.687030 (rank : 17)	θ value	0 (rank : 2)
Query Neighborhood Hits	249	Target Neighborhood Hits	146	Shared Neighborhood Hits	49
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RGPD8_HUMAN
NC score	0.685101 (rank : 18)	θ value	0 (rank : 5)
Query Neighborhood Hits	249	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP22_HUMAN
NC score	0.684212 (rank : 19)	θ value	0 (rank : 1)
Query Neighborhood Hits	249	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

PPID_MOUSE
NC score	0.671744 (rank : 20)	θ value	3.37202e-47 (rank : 12)
Query Neighborhood Hits	249	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PPID_HUMAN
NC score	0.669439 (rank : 21)	θ value	1.28137e-46 (rank : 13)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	39
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

PPIL2_MOUSE
NC score	0.660428 (rank : 22)	θ value	1.80048e-24 (rank : 26)
Query Neighborhood Hits	249	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D787, Q542A2, Q9CZL1	Gene names	Ppil2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

PPIL2_HUMAN
NC score	0.659007 (rank : 23)	θ value	1.16704e-23 (rank : 28)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q13356, Q13357, Q8TAH2, Q9BWR8	Gene names	PPIL2
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase-like 2 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60).

NKTR_MOUSE
NC score	0.657120 (rank : 24)	θ value	1.42001e-37 (rank : 25)
Query Neighborhood Hits	249	Target Neighborhood Hits	417	Shared Neighborhood Hits	46
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RANG_MOUSE
NC score	0.653299 (rank : 25)	θ value	3.26607e-42 (rank : 19)
Query Neighborhood Hits	249	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
NC score	0.648644 (rank : 26)	θ value	4.2656e-42 (rank : 20)
Query Neighborhood Hits	249	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

PPIE_HUMAN
NC score	0.641317 (rank : 27)	θ value	8.28633e-54 (rank : 10)
Query Neighborhood Hits	249	Target Neighborhood Hits	205	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNP9, O43634, O43635, Q5TGA0, Q9UIZ5	Gene names	PPIE, CYP33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPIE_MOUSE
NC score	0.641208 (rank : 28)	θ value	8.28633e-54 (rank : 11)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZH3, Q9D8C0	Gene names	Ppie, Cyp33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

NKTR_HUMAN
NC score	0.629340 (rank : 29)	θ value	1.42001e-37 (rank : 24)
Query Neighborhood Hits	249	Target Neighborhood Hits	658	Shared Neighborhood Hits	60
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPWD1_MOUSE
NC score	0.623515 (rank : 30)	θ value	2.69047e-20 (rank : 32)
Query Neighborhood Hits	249	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CEC6	Gene names	Ppwd1
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPWD1_HUMAN
NC score	0.621677 (rank : 31)	θ value	4.58923e-20 (rank : 33)
Query Neighborhood Hits	249	Target Neighborhood Hits	136	Shared Neighborhood Hits	29
SwissProt Accessions	Q96BP3, Q15002, Q7KZ89	Gene names	PPWD1, KIAA0073
Domain Architecture	No domain graphic available
Description	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8).

PPIG_HUMAN
NC score	0.616422 (rank : 32)	θ value	1.05066e-40 (rank : 23)
Query Neighborhood Hits	249	Target Neighborhood Hits	670	Shared Neighborhood Hits	55
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

PPIL4_MOUSE
NC score	0.514074 (rank : 33)	θ value	1.29331e-14 (rank : 34)
Query Neighborhood Hits	249	Target Neighborhood Hits	232	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CXG3, Q3TJX1, Q68FC7, Q9CT22	Gene names	Ppil4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

PPIL4_HUMAN
NC score	0.511023 (rank : 34)	θ value	1.68911e-14 (rank : 35)
Query Neighborhood Hits	249	Target Neighborhood Hits	264	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

NU153_HUMAN
NC score	0.393938 (rank : 35)	θ value	2.67181e-44 (rank : 16)
Query Neighborhood Hits	249	Target Neighborhood Hits	227	Shared Neighborhood Hits	39
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

RANB3_HUMAN
NC score	0.240532 (rank : 36)	θ value	1.43324e-05 (rank : 39)
Query Neighborhood Hits	249	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RANB3_MOUSE
NC score	0.233073 (rank : 37)	θ value	1.87187e-05 (rank : 40)
Query Neighborhood Hits	249	Target Neighborhood Hits	123	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

ZRAN1_HUMAN
NC score	0.191855 (rank : 38)	θ value	1.25267e-09 (rank : 37)
Query Neighborhood Hits	249	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

RNF31_HUMAN
NC score	0.165524 (rank : 39)	θ value	1.25267e-09 (rank : 36)
Query Neighborhood Hits	249	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.157077 (rank : 40)	θ value	2.79066e-09 (rank : 38)
Query Neighborhood Hits	249	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

YAF2_MOUSE
NC score	0.132293 (rank : 41)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	249	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

YAF2_HUMAN
NC score	0.129869 (rank : 42)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	249	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

RYBP_HUMAN
NC score	0.125651 (rank : 43)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	249	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

RYBP_MOUSE
NC score	0.118859 (rank : 44)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

CDC27_HUMAN
NC score	0.117324 (rank : 45)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	249	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

BBS4_HUMAN
NC score	0.099118 (rank : 46)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	249	Target Neighborhood Hits	109	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

NEIL3_HUMAN
NC score	0.096930 (rank : 47)	θ value	0.000158464 (rank : 41)
Query Neighborhood Hits	249	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

CDC23_MOUSE
NC score	0.095312 (rank : 48)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	249	Target Neighborhood Hits	65	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CDC23_HUMAN
NC score	0.094716 (rank : 49)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	249	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

ZRAB2_HUMAN
NC score	0.093259 (rank : 50)	θ value	0.0252991 (rank : 57)
Query Neighborhood Hits	249	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

NUP50_MOUSE
NC score	0.092564 (rank : 51)	θ value	0.0113563 (rank : 49)
Query Neighborhood Hits	249	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIH2, Q9CU02, Q9JK85	Gene names	Nup50, Npap60
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

NEIL3_MOUSE
NC score	0.090181 (rank : 52)	θ value	0.00869519 (rank : 47)
Query Neighborhood Hits	249	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

PEX5_HUMAN
NC score	0.089115 (rank : 53)	θ value	0.0431538 (rank : 61)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

CIR_HUMAN
NC score	0.084773 (rank : 54)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	249	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

NU214_HUMAN
NC score	0.081527 (rank : 55)	θ value	0.00509761 (rank : 43)
Query Neighborhood Hits	249	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

IFT88_HUMAN
NC score	0.081264 (rank : 56)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	249	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

RBP24_HUMAN
NC score	0.080982 (rank : 57)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	249	Target Neighborhood Hits	1559	Shared Neighborhood Hits	41
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.080830 (rank : 58)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	249	Target Neighborhood Hits	1558	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

BBS4_MOUSE
NC score	0.079344 (rank : 59)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	249	Target Neighborhood Hits	95	Shared Neighborhood Hits	20
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

GCC2_MOUSE
NC score	0.076230 (rank : 60)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	249	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PEX5_MOUSE
NC score	0.074548 (rank : 61)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	249	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

OGT1_HUMAN
NC score	0.073004 (rank : 62)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	249	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

NUP50_HUMAN
NC score	0.057614 (rank : 63)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	249	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKX7, O75644, Q9NPM9, Q9NPR6, Q9P1K5	Gene names	NUP50, NPAP60L
Domain Architecture
Description	Nucleoporin 50 kDa (Nuclear pore-associated protein 60 kDa-like).

K0372_HUMAN
NC score	0.056585 (rank : 64)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	249	Target Neighborhood Hits	136	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

PO121_HUMAN
NC score	0.056463 (rank : 65)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	249	Target Neighborhood Hits	344	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

RNPS1_HUMAN
NC score	0.053693 (rank : 66)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	249	Target Neighborhood Hits	285	Shared Neighborhood Hits	16
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.053693 (rank : 67)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	249	Target Neighborhood Hits	285	Shared Neighborhood Hits	16
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

DSPP_HUMAN
NC score	0.051147 (rank : 68)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	249	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ATN1_HUMAN
NC score	0.047739 (rank : 69)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	249	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

PO121_MOUSE
NC score	0.047405 (rank : 70)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	249	Target Neighborhood Hits	345	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TAB2_HUMAN
NC score	0.043214 (rank : 71)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	249	Target Neighborhood Hits	169	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TTC12_MOUSE
NC score	0.043090 (rank : 72)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	249	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

JIP4_MOUSE
NC score	0.042746 (rank : 73)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	249	Target Neighborhood Hits	593	Shared Neighborhood Hits	26
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

CO039_MOUSE
NC score	0.042453 (rank : 74)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	249	Target Neighborhood Hits	445	Shared Neighborhood Hits	34
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

IFT88_MOUSE
NC score	0.042400 (rank : 75)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	249	Target Neighborhood Hits	124	Shared Neighborhood Hits	20
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

TAB3_MOUSE
NC score	0.042271 (rank : 76)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	249	Target Neighborhood Hits	273	Shared Neighborhood Hits	35
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

JIP4_HUMAN
NC score	0.040571 (rank : 77)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	249	Target Neighborhood Hits	585	Shared Neighborhood Hits	24
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

KU70_HUMAN
NC score	0.040062 (rank : 78)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	249	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P12956, Q9UCQ2, Q9UCQ3	Gene names	XRCC6, G22P1
Domain Architecture
Description	ATP-dependent DNA helicase 2 subunit 1 (EC 3.6.1.-) (ATP-dependent DNA helicase II 70 kDa subunit) (Lupus Ku autoantigen protein p70) (Ku70) (70 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box-binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA-repair protein XRCC6).

DSPP_MOUSE
NC score	0.039589 (rank : 79)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	249	Target Neighborhood Hits	491	Shared Neighborhood Hits	33
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TTC12_HUMAN
NC score	0.039305 (rank : 80)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

DOT1L_HUMAN
NC score	0.038714 (rank : 81)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	249	Target Neighborhood Hits	660	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MNAB_HUMAN
NC score	0.036622 (rank : 82)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	249	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

TAB2_MOUSE
NC score	0.036527 (rank : 83)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	249	Target Neighborhood Hits	245	Shared Neighborhood Hits	26
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

SYG_HUMAN
NC score	0.036152 (rank : 84)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	249	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	P41250, Q969Y1	Gene names	GARS
Domain Architecture
Description	Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS).

IL4RA_HUMAN
NC score	0.036114 (rank : 85)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	249	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

SC24A_MOUSE
NC score	0.035148 (rank : 86)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	249	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

MBD6_HUMAN
NC score	0.033905 (rank : 87)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	249	Target Neighborhood Hits	349	Shared Neighborhood Hits	27
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

P80C_HUMAN
NC score	0.032611 (rank : 88)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	249	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

NOLC1_HUMAN
NC score	0.032491 (rank : 89)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	249	Target Neighborhood Hits	452	Shared Neighborhood Hits	22
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ARI1A_HUMAN
NC score	0.031333 (rank : 90)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	249	Target Neighborhood Hits	787	Shared Neighborhood Hits	45
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

II2B_MOUSE
NC score	0.031098 (rank : 91)	θ value	2.36792 (rank : 132)
Query Neighborhood Hits	249	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R002	Gene names	Ifi202b
Domain Architecture
Description	Interferon-activable protein 202b (Ifi-202b) (Interferon-inducible protein p202b).

II2A_MOUSE
NC score	0.030667 (rank : 92)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	249	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P15091	Gene names	Ifi202a, Ifi202
Domain Architecture
Description	Interferon-activable protein 202a (Ifi-202a) (Interferon-inducible protein p202a).

MNAB_MOUSE
NC score	0.030489 (rank : 93)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	249	Target Neighborhood Hits	231	Shared Neighborhood Hits	9
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

HORN_HUMAN
NC score	0.029957 (rank : 94)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

RBM5_MOUSE
NC score	0.029468 (rank : 95)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE7, Q3UZ19, Q99KV9	Gene names	Rbm5, Luca15
Domain Architecture	No domain graphic available
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15).

SYCP1_MOUSE
NC score	0.029407 (rank : 96)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	249	Target Neighborhood Hits	1456	Shared Neighborhood Hits	45
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RBM5_HUMAN
NC score	0.029103 (rank : 97)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	10
SwissProt Accessions	P52756, Q93021, Q9BU14, Q9UKY8, Q9UL24	Gene names	RBM5
Domain Architecture
Description	RNA-binding protein 5 (RNA-binding motif protein 5) (Tumor suppressor LUCA15) (Protein G15) (NY-REN-9 antigen).

SPT5H_MOUSE
NC score	0.029078 (rank : 98)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	249	Target Neighborhood Hits	437	Shared Neighborhood Hits	45
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

RPTN_MOUSE
NC score	0.028741 (rank : 99)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	249	Target Neighborhood Hits	650	Shared Neighborhood Hits	36
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

MAGE1_HUMAN
NC score	0.028558 (rank : 100)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	249	Target Neighborhood Hits	1389	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SPT5H_HUMAN
NC score	0.028171 (rank : 101)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	249	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SC24C_HUMAN
NC score	0.028054 (rank : 102)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	249	Target Neighborhood Hits	662	Shared Neighborhood Hits	50
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ARI1B_HUMAN
NC score	0.027869 (rank : 103)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	249	Target Neighborhood Hits	567	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

WASIP_MOUSE
NC score	0.027738 (rank : 104)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	249	Target Neighborhood Hits	392	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CMTA2_HUMAN
NC score	0.027561 (rank : 105)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	249	Target Neighborhood Hits	199	Shared Neighborhood Hits	9
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CLC4F_HUMAN
NC score	0.027065 (rank : 106)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	249	Target Neighborhood Hits	513	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

EVI2B_HUMAN
NC score	0.026384 (rank : 107)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	249	Target Neighborhood Hits	135	Shared Neighborhood Hits	14
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

K1543_MOUSE
NC score	0.025450 (rank : 108)	θ value	2.36792 (rank : 133)
Query Neighborhood Hits	249	Target Neighborhood Hits	497	Shared Neighborhood Hits	34
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

HDGR3_HUMAN
NC score	0.025260 (rank : 109)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	249	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

TCOF_MOUSE
NC score	0.024933 (rank : 110)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	249	Target Neighborhood Hits	471	Shared Neighborhood Hits	22
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

PHF3_HUMAN
NC score	0.024872 (rank : 111)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	249	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

CN032_HUMAN
NC score	0.024420 (rank : 112)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	249	Target Neighborhood Hits	267	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

HDGR3_MOUSE
NC score	0.024323 (rank : 113)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	249	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

CV106_HUMAN
NC score	0.024084 (rank : 114)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P0N0, Q86V14, Q96PY4, Q9NUR5, Q9Y4X9	Gene names	C14orf106, KIAA1903
Domain Architecture	No domain graphic available
Description	Protein C14orf106 (P243).

PHF14_HUMAN
NC score	0.023658 (rank : 115)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	249	Target Neighborhood Hits	447	Shared Neighborhood Hits	23
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PABP1_MOUSE
NC score	0.023079 (rank : 116)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	249	Target Neighborhood Hits	278	Shared Neighborhood Hits	16
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_HUMAN
NC score	0.022768 (rank : 117)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	249	Target Neighborhood Hits	269	Shared Neighborhood Hits	12
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

AP3B1_HUMAN
NC score	0.022767 (rank : 118)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	249	Target Neighborhood Hits	283	Shared Neighborhood Hits	13
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

DEN1A_HUMAN
NC score	0.022595 (rank : 119)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	249	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

TIM44_MOUSE
NC score	0.022572 (rank : 120)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	249	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

PHF14_MOUSE
NC score	0.022321 (rank : 121)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	249	Target Neighborhood Hits	342	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

RERE_MOUSE
NC score	0.021649 (rank : 122)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	249	Target Neighborhood Hits	785	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

MUC13_MOUSE
NC score	0.021422 (rank : 123)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	249	Target Neighborhood Hits	447	Shared Neighborhood Hits	15
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CMTA2_MOUSE
NC score	0.021420 (rank : 124)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	249	Target Neighborhood Hits	216	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DEN1A_MOUSE
NC score	0.020715 (rank : 125)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	249	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MLKL_MOUSE
NC score	0.020703 (rank : 126)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	249	Target Neighborhood Hits	707	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

HSF1_MOUSE
NC score	0.019959 (rank : 127)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	249	Target Neighborhood Hits	267	Shared Neighborhood Hits	22
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

IFIT1_HUMAN
NC score	0.019457 (rank : 128)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	249	Target Neighborhood Hits	56	Shared Neighborhood Hits	14
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

NFAT5_HUMAN
NC score	0.018863 (rank : 129)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	249	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

LDB3_MOUSE
NC score	0.018712 (rank : 130)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	249	Target Neighborhood Hits	510	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

RBM6_HUMAN
NC score	0.018602 (rank : 131)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	249	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SFR15_HUMAN
NC score	0.018547 (rank : 132)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	249	Target Neighborhood Hits	368	Shared Neighborhood Hits	24
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

BRPF3_HUMAN
NC score	0.018411 (rank : 133)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	249	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CF152_HUMAN
NC score	0.017907 (rank : 134)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	249	Target Neighborhood Hits	704	Shared Neighborhood Hits	29
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

BRD4_MOUSE
NC score	0.017750 (rank : 135)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	249	Target Neighborhood Hits	845	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

DAXX_MOUSE
NC score	0.017735 (rank : 136)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	249	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

CYLD_HUMAN
NC score	0.017532 (rank : 137)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	249	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

CSN2_HUMAN
NC score	0.017522 (rank : 138)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	249	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P61201, O88950, Q15647, Q6FGP4, Q9BY54, Q9R249, Q9UNI2, Q9UNQ5	Gene names	COPS2, CSN2, TRIP15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

CSN2_MOUSE
NC score	0.017522 (rank : 139)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	249	Target Neighborhood Hits	34	Shared Neighborhood Hits	6
SwissProt Accessions	P61202, O88950, Q15647, Q3V1W6, Q8R5B0, Q9CWU1, Q9R249, Q9UNQ5	Gene names	Cops2, Csn2, Trip15
Domain Architecture
Description	COP9 signalosome complex subunit 2 (Signalosome subunit 2) (SGN2) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (Alien homolog).

MLL2_HUMAN
NC score	0.016192 (rank : 140)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	249	Target Neighborhood Hits	1788	Shared Neighborhood Hits	73
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CD2AP_MOUSE
NC score	0.016180 (rank : 141)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	249	Target Neighborhood Hits	336	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

MLL3_MOUSE
NC score	0.016076 (rank : 142)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	249	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PGCA_MOUSE
NC score	0.015570 (rank : 143)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	249	Target Neighborhood Hits	643	Shared Neighborhood Hits	25
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

NPDC1_HUMAN
NC score	0.015475 (rank : 144)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	249	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQX5, Q9BTD6, Q9BXT3, Q9NQS2, Q9Y434	Gene names	NPDC1
Domain Architecture
Description	Neural proliferation differentiation and control protein 1 precursor (NPDC-1 protein).

DBPA_MOUSE
NC score	0.015260 (rank : 145)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	249	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

ETV5_HUMAN
NC score	0.015202 (rank : 146)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	249	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

MAGC1_HUMAN
NC score	0.015149 (rank : 147)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	249	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAP1B_HUMAN
NC score	0.014881 (rank : 148)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	249	Target Neighborhood Hits	903	Shared Neighborhood Hits	49
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

LYAM2_HUMAN
NC score	0.014806 (rank : 149)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	249	Target Neighborhood Hits	394	Shared Neighborhood Hits	8
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TCGAP_MOUSE
NC score	0.014738 (rank : 150)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	249	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SFPQ_HUMAN
NC score	0.014615 (rank : 151)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	249	Target Neighborhood Hits	986	Shared Neighborhood Hits	49
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

RUFY1_HUMAN
NC score	0.014614 (rank : 152)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	249	Target Neighborhood Hits	848	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

LIPB1_HUMAN
NC score	0.014202 (rank : 153)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	249	Target Neighborhood Hits	640	Shared Neighborhood Hits	17
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

ELOA1_MOUSE
NC score	0.013840 (rank : 154)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	249	Target Neighborhood Hits	152	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MCM3A_HUMAN
NC score	0.013825 (rank : 155)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	249	Target Neighborhood Hits	86	Shared Neighborhood Hits	10
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

SRBP1_HUMAN
NC score	0.013686 (rank : 156)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	249	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CF146_HUMAN
NC score	0.013660 (rank : 157)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	249	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IXS0, Q5JYK1	Gene names	C6orf146
Domain Architecture	No domain graphic available
Description	Protein C6orf146.

PTN23_MOUSE
NC score	0.013615 (rank : 158)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	249	Target Neighborhood Hits	726	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MUCDL_MOUSE
NC score	0.013381 (rank : 159)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	249	Target Neighborhood Hits	461	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MFN1_HUMAN
NC score	0.013308 (rank : 160)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	249	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWA4, O15323, O60639, Q9BZB5, Q9NWQ2	Gene names	MFN1
Domain Architecture
Description	Transmembrane GTPase MFN1 (EC 3.6.5.-) (Mitofusin-1) (Fzo homolog).

SOX3_HUMAN
NC score	0.013131 (rank : 161)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	249	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SYCP1_HUMAN
NC score	0.012978 (rank : 162)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	249	Target Neighborhood Hits	1313	Shared Neighborhood Hits	38
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SOX3_MOUSE
NC score	0.012926 (rank : 163)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	249	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

GREM1_HUMAN
NC score	0.012562 (rank : 164)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	O60565, Q52LV3, Q8N914, Q8N936	Gene names	GREM1, CKTSF1B1, DAND2, DRM, PIG2
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Increased in high glucose protein 2) (IHG-2) (Down-regulated in Mos- transformed cells protein) (Proliferation-inducing gene 2 protein).

GREM1_MOUSE
NC score	0.012507 (rank : 165)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O70326	Gene names	Grem1, Cktsf1b1, Drm
Domain Architecture	No domain graphic available
Description	Gremlin-1 precursor (Cysteine knot superfamily 1, BMP antagonist 1) (Down-regulated in Mos-transformed cells protein).

FHL1_HUMAN
NC score	0.012505 (rank : 166)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	249	Target Neighborhood Hits	436	Shared Neighborhood Hits	6
SwissProt Accessions	Q13642, O95212, Q13230, Q13645, Q5M7Y6, Q9NZ40, Q9UKZ8, Q9Y630	Gene names	FHL1, SLIM1
Domain Architecture
Description	Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM- protein 1) (SLIM 1) (SLIM).

PRGC1_HUMAN
NC score	0.012446 (rank : 167)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	249	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

IRS2_MOUSE
NC score	0.012360 (rank : 168)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	249	Target Neighborhood Hits	248	Shared Neighborhood Hits	17
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

ZFY19_HUMAN
NC score	0.012302 (rank : 169)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	249	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

SGOL2_HUMAN
NC score	0.012250 (rank : 170)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	249	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

CBP_HUMAN
NC score	0.012009 (rank : 171)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	249	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DBPA_HUMAN
NC score	0.011917 (rank : 172)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	249	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	P16989, Q14121, Q969N6	Gene names	CSDA, DBPA
Domain Architecture
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Single-strand DNA-binding protein NF-GMB).

LIPB1_MOUSE
NC score	0.011736 (rank : 173)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	249	Target Neighborhood Hits	727	Shared Neighborhood Hits	23
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

TRIPB_HUMAN
NC score	0.011702 (rank : 174)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	249	Target Neighborhood Hits	1587	Shared Neighborhood Hits	46
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

NEUM_HUMAN
NC score	0.011308 (rank : 175)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	P17677	Gene names	GAP43
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (PP46) (Neural phosphoprotein B-50).

PRG4_HUMAN
NC score	0.011231 (rank : 176)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	249	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CH076_HUMAN
NC score	0.011137 (rank : 177)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	249	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q96K31, Q53HC1	Gene names	C8orf76
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf76.

BRDT_MOUSE
NC score	0.011039 (rank : 178)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	249	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

PLXC1_HUMAN
NC score	0.010954 (rank : 179)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	249	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

CI093_HUMAN
NC score	0.010845 (rank : 180)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	249	Target Neighborhood Hits	1088	Shared Neighborhood Hits	36
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

ETV1_HUMAN
NC score	0.010831 (rank : 181)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	249	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

CNTRB_MOUSE
NC score	0.010444 (rank : 182)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	249	Target Neighborhood Hits	1029	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ETV1_MOUSE
NC score	0.010395 (rank : 183)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	249	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

CD2AP_HUMAN
NC score	0.010217 (rank : 184)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	249	Target Neighborhood Hits	315	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

BCAR1_HUMAN
NC score	0.009912 (rank : 185)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	249	Target Neighborhood Hits	554	Shared Neighborhood Hits	33
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

SOS1_MOUSE
NC score	0.009440 (rank : 186)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	249	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

ZF106_MOUSE
NC score	0.009384 (rank : 187)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	249	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

FIBA_HUMAN
NC score	0.009310 (rank : 188)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	5
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

MUC2_HUMAN
NC score	0.009263 (rank : 189)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	249	Target Neighborhood Hits	906	Shared Neighborhood Hits	40
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

GEPH_HUMAN
NC score	0.009178 (rank : 190)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	249	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NQX3, Q9P2G2	Gene names	GPHN, GPH, KIAA1385
Domain Architecture
Description	Gephyrin.

MYH3_HUMAN
NC score	0.008800 (rank : 191)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	249	Target Neighborhood Hits	1660	Shared Neighborhood Hits	38
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MSH4_MOUSE
NC score	0.008473 (rank : 192)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	249	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

KIF17_HUMAN
NC score	0.008166 (rank : 193)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	249	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

LRC40_HUMAN
NC score	0.008076 (rank : 194)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	249	Target Neighborhood Hits	313	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

S4A4_MOUSE
NC score	0.007948 (rank : 195)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	249	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

IRX5_HUMAN
NC score	0.007918 (rank : 196)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	249	Target Neighborhood Hits	362	Shared Neighborhood Hits	12
SwissProt Accessions	P78411, P78416, Q7Z2E1	Gene names	IRX5, IRX2A, IRXB2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A).

TAXB1_HUMAN
NC score	0.007689 (rank : 197)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	249	Target Neighborhood Hits	829	Shared Neighborhood Hits	28
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

ARMX2_MOUSE
NC score	0.007628 (rank : 198)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	249	Target Neighborhood Hits	349	Shared Neighborhood Hits	25
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

TRI66_MOUSE
NC score	0.007614 (rank : 199)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	249	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

S4A4_HUMAN
NC score	0.007531 (rank : 200)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	249	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

RBX2_HUMAN
NC score	0.007299 (rank : 201)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	249	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBF6, Q9BXN8, Q9Y5M7	Gene names	RNF7, RBX2, ROC2, SAG
Domain Architecture	No domain graphic available
Description	RING-box protein 2 (Rbx2) (RING finger protein 7) (Regulator of cullins 2) (CKII beta-binding protein 1) (CKBBP1) (Sensitive to apoptosis gene protein).

RPGR_MOUSE
NC score	0.007224 (rank : 202)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	249	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

A4_HUMAN
NC score	0.007065 (rank : 203)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	249	Target Neighborhood Hits	274	Shared Neighborhood Hits	11
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

SOS1_HUMAN
NC score	0.006976 (rank : 204)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	249	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

ZEP2_HUMAN
NC score	0.006780 (rank : 205)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	249	Target Neighborhood Hits	937	Shared Neighborhood Hits	28
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

TIP60_MOUSE
NC score	0.006559 (rank : 206)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	249	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

SYTL5_HUMAN
NC score	0.006501 (rank : 207)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	249	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

TNKS1_HUMAN
NC score	0.006405 (rank : 208)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	249	Target Neighborhood Hits	477	Shared Neighborhood Hits	21
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

SHAN1_HUMAN
NC score	0.006315 (rank : 209)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	249	Target Neighborhood Hits	1041	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SYNP2_HUMAN
NC score	0.006255 (rank : 210)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	249	Target Neighborhood Hits	323	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

TREF1_HUMAN
NC score	0.006047 (rank : 211)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	249	Target Neighborhood Hits	651	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

IRX5_MOUSE
NC score	0.006016 (rank : 212)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	249	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKQ4, Q80WV4, Q9JLL5	Gene names	Irx5, Irxb2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2).

TIP60_HUMAN
NC score	0.005912 (rank : 213)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	249	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

HNRL1_HUMAN
NC score	0.005665 (rank : 214)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	249	Target Neighborhood Hits	173	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

DCR1A_MOUSE
NC score	0.005410 (rank : 215)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	249	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

PADI3_MOUSE
NC score	0.005102 (rank : 216)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	249	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).

AMOL2_MOUSE
NC score	0.005076 (rank : 217)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	249	Target Neighborhood Hits	591	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

IQEC3_HUMAN
NC score	0.004531 (rank : 218)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	249	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

RENT1_MOUSE
NC score	0.004433 (rank : 219)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	249	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

MYH4_HUMAN
NC score	0.004285 (rank : 220)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	249	Target Neighborhood Hits	1377	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

ZEP2_MOUSE
NC score	0.004251 (rank : 221)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	249	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

GRLF1_HUMAN
NC score	0.004189 (rank : 222)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	249	Target Neighborhood Hits	167	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

TRPV1_MOUSE
NC score	0.003626 (rank : 223)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	249	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

SCUB3_MOUSE
NC score	0.003341 (rank : 224)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	249	Target Neighborhood Hits	442	Shared Neighborhood Hits	7
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

RAI14_MOUSE
NC score	0.003181 (rank : 225)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	249	Target Neighborhood Hits	1505	Shared Neighborhood Hits	44
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SCUB3_HUMAN
NC score	0.003050 (rank : 226)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	249	Target Neighborhood Hits	428	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ATOH1_MOUSE
NC score	0.003018 (rank : 227)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	249	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

GIT2_HUMAN
NC score	0.002776 (rank : 228)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	249	Target Neighborhood Hits	381	Shared Neighborhood Hits	17
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

KLF17_HUMAN
NC score	0.002524 (rank : 229)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	249	Target Neighborhood Hits	882	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JT82, Q86VQ7, Q8N805	Gene names	KLF17, ZNF393
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 17 (Zinc finger protein 393).

DMD_MOUSE
NC score	0.002411 (rank : 230)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	249	Target Neighborhood Hits	1111	Shared Neighborhood Hits	27
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

ZFHX2_HUMAN
NC score	0.002396 (rank : 231)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	249	Target Neighborhood Hits	1178	Shared Neighborhood Hits	24
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

SIGL5_MOUSE
NC score	0.002114 (rank : 232)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	249	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

AT1A3_MOUSE
NC score	0.001551 (rank : 233)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	249	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PIC6	Gene names	Atp1a3
Domain Architecture	No domain graphic available
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

AT1A3_HUMAN
NC score	0.001548 (rank : 234)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	249	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P13637, Q16732, Q16735, Q969K5	Gene names	ATP1A3
Domain Architecture
Description	Sodium/potassium-transporting ATPase alpha-3 chain (EC 3.6.3.9) (Sodium pump 3) (Na+/K+ ATPase 3) (Alpha(III)).

ATBF1_MOUSE
NC score	0.001424 (rank : 235)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	249	Target Neighborhood Hits	1841	Shared Neighborhood Hits	53
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DGKI_HUMAN
NC score	0.001401 (rank : 236)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	249	Target Neighborhood Hits	609	Shared Neighborhood Hits	8
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

NCA11_MOUSE
NC score	0.000826 (rank : 237)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	249	Target Neighborhood Hits	661	Shared Neighborhood Hits	16
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

GLI1_HUMAN
NC score	0.000641 (rank : 238)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	249	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

CO4A1_HUMAN
NC score	0.000481 (rank : 239)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	249	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

FOXGA_HUMAN
NC score	0.000219 (rank : 240)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	249	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

SUHW4_HUMAN
NC score	0.000134 (rank : 241)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	249	Target Neighborhood Hits	860	Shared Neighborhood Hits	22
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

SUHW4_MOUSE
NC score	-0.000056 (rank : 242)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	249	Target Neighborhood Hits	737	Shared Neighborhood Hits	15
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

5HT5A_MOUSE
NC score	-0.000584 (rank : 243)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	249	Target Neighborhood Hits	615	Shared Neighborhood Hits	6
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

ZBT38_HUMAN
NC score	-0.001622 (rank : 244)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	249	Target Neighborhood Hits	885	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NAP3	Gene names	ZBTB38
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 38.

ACK1_MOUSE
NC score	-0.001750 (rank : 245)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	249	Target Neighborhood Hits	1080	Shared Neighborhood Hits	24
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CELR1_MOUSE
NC score	-0.002031 (rank : 246)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	249	Target Neighborhood Hits	617	Shared Neighborhood Hits	10
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

WNK4_HUMAN
NC score	-0.002075 (rank : 247)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	249	Target Neighborhood Hits	1043	Shared Neighborhood Hits	20
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZNF77_HUMAN
NC score	-0.002693 (rank : 248)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	249	Target Neighborhood Hits	759	Shared Neighborhood Hits	13
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

MAST1_HUMAN
NC score	-0.004104 (rank : 249)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	249	Target Neighborhood Hits	1146	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

KPCG_HUMAN
NC score	-0.004750 (rank : 250)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	249	Target Neighborhood Hits	1126	Shared Neighborhood Hits	8
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

TITIN_HUMAN
NC score	-0.005751 (rank : 251)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	249	Target Neighborhood Hits	2923	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).