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Network neighborhood for query Sequence : BRPF3_HUMAN

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BRPF3_HUMAN
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BRD1_HUMAN
θ value	0 (rank : 1)	NC score	0.977851 (rank : 2)
Query Neighborhood Hits	217	Target Neighborhood Hits	188	Shared Neighborhood Hits	122
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRPF1_HUMAN
θ value	8.0589e-150 (rank : 3)	NC score	0.959212 (rank : 3)
Query Neighborhood Hits	217	Target Neighborhood Hits	259	Shared Neighborhood Hits	124
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE1_MOUSE
θ value	1.36585e-56 (rank : 4)	NC score	0.805278 (rank : 6)
Query Neighborhood Hits	217	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_HUMAN
θ value	1.51013e-55 (rank : 5)	NC score	0.806292 (rank : 5)
Query Neighborhood Hits	217	Target Neighborhood Hits	140	Shared Neighborhood Hits	83
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_MOUSE
θ value	1.2784e-54 (rank : 6)	NC score	0.808399 (rank : 4)
Query Neighborhood Hits	217	Target Neighborhood Hits	174	Shared Neighborhood Hits	88
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_HUMAN
θ value	8.02596e-49 (rank : 7)	NC score	0.804820 (rank : 7)
Query Neighborhood Hits	217	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
θ value	1.97686e-47 (rank : 8)	NC score	0.798375 (rank : 8)
Query Neighborhood Hits	217	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	1.67352e-46 (rank : 9)	NC score	0.759883 (rank : 10)
Query Neighborhood Hits	217	Target Neighborhood Hits	560	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

AF17_HUMAN
θ value	4.88048e-38 (rank : 10)	NC score	0.781998 (rank : 9)
Query Neighborhood Hits	217	Target Neighborhood Hits	230	Shared Neighborhood Hits	64
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_HUMAN
θ value	1.85459e-37 (rank : 11)	NC score	0.748846 (rank : 12)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	1.85459e-37 (rank : 12)	NC score	0.752409 (rank : 11)
Query Neighborhood Hits	217	Target Neighborhood Hits	182	Shared Neighborhood Hits	61
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

PHF14_MOUSE
θ value	1.62847e-25 (rank : 13)	NC score	0.712236 (rank : 13)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JHD3B_HUMAN
θ value	3.62785e-25 (rank : 14)	NC score	0.572381 (rank : 16)
Query Neighborhood Hits	217	Target Neighborhood Hits	128	Shared Neighborhood Hits	46
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PHF14_HUMAN
θ value	3.62785e-25 (rank : 15)	NC score	0.700383 (rank : 14)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	104
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

JHD3B_MOUSE
θ value	4.73814e-25 (rank : 16)	NC score	0.572642 (rank : 15)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_MOUSE
θ value	3.07116e-24 (rank : 17)	NC score	0.564148 (rank : 18)
Query Neighborhood Hits	217	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
θ value	1.99067e-23 (rank : 18)	NC score	0.563123 (rank : 19)
Query Neighborhood Hits	217	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	1.99067e-23 (rank : 19)	NC score	0.564907 (rank : 17)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
θ value	9.87957e-23 (rank : 20)	NC score	0.559958 (rank : 20)
Query Neighborhood Hits	217	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

BRD7_MOUSE
θ value	5.25075e-16 (rank : 21)	NC score	0.490125 (rank : 24)
Query Neighborhood Hits	217	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD7_HUMAN
θ value	6.85773e-16 (rank : 22)	NC score	0.496036 (rank : 21)
Query Neighborhood Hits	217	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD9_HUMAN
θ value	1.42992e-13 (rank : 23)	NC score	0.494914 (rank : 22)
Query Neighborhood Hits	217	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	1.86753e-13 (rank : 24)	NC score	0.491142 (rank : 23)
Query Neighborhood Hits	217	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

ATAD2_HUMAN
θ value	2.98157e-11 (rank : 25)	NC score	0.223215 (rank : 95)
Query Neighborhood Hits	217	Target Neighborhood Hits	322	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	1.133e-10 (rank : 26)	NC score	0.221181 (rank : 96)
Query Neighborhood Hits	217	Target Neighborhood Hits	167	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BAZ2B_HUMAN
θ value	5.62301e-10 (rank : 27)	NC score	0.445781 (rank : 27)
Query Neighborhood Hits	217	Target Neighborhood Hits	803	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CECR2_HUMAN
θ value	1.63604e-09 (rank : 28)	NC score	0.385788 (rank : 40)
Query Neighborhood Hits	217	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BPTF_HUMAN
θ value	2.79066e-09 (rank : 29)	NC score	0.426207 (rank : 30)
Query Neighborhood Hits	217	Target Neighborhood Hits	786	Shared Neighborhood Hits	120
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

TAF1_HUMAN
θ value	2.79066e-09 (rank : 30)	NC score	0.399627 (rank : 36)
Query Neighborhood Hits	217	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

GCNL2_HUMAN
θ value	4.76016e-09 (rank : 31)	NC score	0.403440 (rank : 34)
Query Neighborhood Hits	217	Target Neighborhood Hits	159	Shared Neighborhood Hits	54
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

TAF1L_HUMAN
θ value	6.21693e-09 (rank : 32)	NC score	0.389880 (rank : 38)
Query Neighborhood Hits	217	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

GCNL2_MOUSE
θ value	1.06045e-08 (rank : 33)	NC score	0.400503 (rank : 35)
Query Neighborhood Hits	217	Target Neighborhood Hits	146	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

BRD2_HUMAN
θ value	1.38499e-08 (rank : 34)	NC score	0.405106 (rank : 33)
Query Neighborhood Hits	217	Target Neighborhood Hits	242	Shared Neighborhood Hits	61
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

TIF1A_HUMAN
θ value	1.80886e-08 (rank : 35)	NC score	0.380073 (rank : 43)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	99
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

BRD8_HUMAN
θ value	5.26297e-08 (rank : 36)	NC score	0.397221 (rank : 37)
Query Neighborhood Hits	217	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	5.26297e-08 (rank : 37)	NC score	0.378661 (rank : 45)
Query Neighborhood Hits	217	Target Neighborhood Hits	422	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

SMCA4_HUMAN
θ value	6.87365e-08 (rank : 38)	NC score	0.189418 (rank : 108)
Query Neighborhood Hits	217	Target Neighborhood Hits	597	Shared Neighborhood Hits	80
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BRD4_MOUSE
θ value	8.97725e-08 (rank : 39)	NC score	0.365430 (rank : 51)
Query Neighborhood Hits	217	Target Neighborhood Hits	845	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PCAF_HUMAN
θ value	8.97725e-08 (rank : 40)	NC score	0.418659 (rank : 32)
Query Neighborhood Hits	217	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRD4_HUMAN
θ value	1.17247e-07 (rank : 41)	NC score	0.363523 (rank : 52)
Query Neighborhood Hits	217	Target Neighborhood Hits	851	Shared Neighborhood Hits	84
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CBP_MOUSE
θ value	1.17247e-07 (rank : 42)	NC score	0.313547 (rank : 61)
Query Neighborhood Hits	217	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TIF1A_MOUSE
θ value	1.17247e-07 (rank : 43)	NC score	0.381083 (rank : 42)
Query Neighborhood Hits	217	Target Neighborhood Hits	307	Shared Neighborhood Hits	101
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BAZ2A_HUMAN
θ value	1.99992e-07 (rank : 44)	NC score	0.435106 (rank : 28)
Query Neighborhood Hits	217	Target Neighborhood Hits	780	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	2.61198e-07 (rank : 45)	NC score	0.429890 (rank : 29)
Query Neighborhood Hits	217	Target Neighborhood Hits	744	Shared Neighborhood Hits	121
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BRWD1_MOUSE
θ value	2.61198e-07 (rank : 46)	NC score	0.211227 (rank : 98)
Query Neighborhood Hits	217	Target Neighborhood Hits	478	Shared Neighborhood Hits	56
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

EP300_HUMAN
θ value	2.61198e-07 (rank : 47)	NC score	0.328013 (rank : 58)
Query Neighborhood Hits	217	Target Neighborhood Hits	821	Shared Neighborhood Hits	91
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BRD3_MOUSE
θ value	3.41135e-07 (rank : 48)	NC score	0.387631 (rank : 39)
Query Neighborhood Hits	217	Target Neighborhood Hits	402	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CBP_HUMAN
θ value	3.41135e-07 (rank : 49)	NC score	0.325797 (rank : 60)
Query Neighborhood Hits	217	Target Neighborhood Hits	941	Shared Neighborhood Hits	86
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PHF10_MOUSE
θ value	3.41135e-07 (rank : 50)	NC score	0.368171 (rank : 49)
Query Neighborhood Hits	217	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

BAZ1A_HUMAN
θ value	5.81887e-07 (rank : 51)	NC score	0.451922 (rank : 25)
Query Neighborhood Hits	217	Target Neighborhood Hits	693	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PHF10_HUMAN
θ value	5.81887e-07 (rank : 52)	NC score	0.370741 (rank : 48)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

BRD3_HUMAN
θ value	1.29631e-06 (rank : 53)	NC score	0.384782 (rank : 41)
Query Neighborhood Hits	217	Target Neighborhood Hits	369	Shared Neighborhood Hits	65
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BAZ1B_MOUSE
θ value	2.21117e-06 (rank : 54)	NC score	0.451716 (rank : 26)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1B_HUMAN
θ value	2.88788e-06 (rank : 55)	NC score	0.419436 (rank : 31)
Query Neighborhood Hits	217	Target Neighborhood Hits	701	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BRDT_MOUSE
θ value	3.77169e-06 (rank : 56)	NC score	0.373832 (rank : 46)
Query Neighborhood Hits	217	Target Neighborhood Hits	243	Shared Neighborhood Hits	57
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRWD1_HUMAN
θ value	3.77169e-06 (rank : 57)	NC score	0.211316 (rank : 97)
Query Neighborhood Hits	217	Target Neighborhood Hits	448	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SMCA2_HUMAN
θ value	4.92598e-06 (rank : 58)	NC score	0.181815 (rank : 110)
Query Neighborhood Hits	217	Target Neighborhood Hits	503	Shared Neighborhood Hits	76
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

PKCB1_HUMAN
θ value	6.43352e-06 (rank : 59)	NC score	0.378843 (rank : 44)
Query Neighborhood Hits	217	Target Neighborhood Hits	488	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BRDT_HUMAN
θ value	1.09739e-05 (rank : 60)	NC score	0.372006 (rank : 47)
Query Neighborhood Hits	217	Target Neighborhood Hits	280	Shared Neighborhood Hits	62
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

PB1_HUMAN
θ value	1.43324e-05 (rank : 61)	NC score	0.367615 (rank : 50)
Query Neighborhood Hits	217	Target Neighborhood Hits	261	Shared Neighborhood Hits	55
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TIF1G_MOUSE
θ value	1.43324e-05 (rank : 62)	NC score	0.328234 (rank : 57)
Query Neighborhood Hits	217	Target Neighborhood Hits	498	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
θ value	2.44474e-05 (rank : 63)	NC score	0.327445 (rank : 59)
Query Neighborhood Hits	217	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI66_HUMAN
θ value	0.000158464 (rank : 64)	NC score	0.354540 (rank : 53)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	107
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	0.000158464 (rank : 65)	NC score	0.351135 (rank : 54)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	110
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PHF1_HUMAN
θ value	0.00035302 (rank : 66)	NC score	0.309486 (rank : 62)
Query Neighborhood Hits	217	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	0.00035302 (rank : 67)	NC score	0.309206 (rank : 63)
Query Neighborhood Hits	217	Target Neighborhood Hits	116	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

CHD3_HUMAN
θ value	0.000602161 (rank : 68)	NC score	0.207031 (rank : 99)
Query Neighborhood Hits	217	Target Neighborhood Hits	397	Shared Neighborhood Hits	85
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
θ value	0.000602161 (rank : 69)	NC score	0.206215 (rank : 100)
Query Neighborhood Hits	217	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

AIRE_MOUSE
θ value	0.000786445 (rank : 70)	NC score	0.331009 (rank : 56)
Query Neighborhood Hits	217	Target Neighborhood Hits	196	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

EPC1_MOUSE
θ value	0.00102713 (rank : 71)	NC score	0.168938 (rank : 117)
Query Neighborhood Hits	217	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MYST3_HUMAN
θ value	0.00102713 (rank : 72)	NC score	0.244335 (rank : 83)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	109
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	0.00102713 (rank : 73)	NC score	0.241952 (rank : 86)
Query Neighborhood Hits	217	Target Neighborhood Hits	688	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PHF7_MOUSE
θ value	0.00102713 (rank : 74)	NC score	0.254518 (rank : 75)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_HUMAN
θ value	0.00134147 (rank : 75)	NC score	0.232715 (rank : 93)
Query Neighborhood Hits	217	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

CHD4_HUMAN
θ value	0.00175202 (rank : 76)	NC score	0.204439 (rank : 101)
Query Neighborhood Hits	217	Target Neighborhood Hits	365	Shared Neighborhood Hits	90
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.00175202 (rank : 77)	NC score	0.204292 (rank : 102)
Query Neighborhood Hits	217	Target Neighborhood Hits	408	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

EPC1_HUMAN
θ value	0.00175202 (rank : 78)	NC score	0.172447 (rank : 115)
Query Neighborhood Hits	217	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MLL3_MOUSE
θ value	0.00175202 (rank : 79)	NC score	0.256864 (rank : 71)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

DPF1_MOUSE
θ value	0.00390308 (rank : 80)	NC score	0.255641 (rank : 73)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL4_HUMAN
θ value	0.00390308 (rank : 81)	NC score	0.255948 (rank : 72)
Query Neighborhood Hits	217	Target Neighborhood Hits	722	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PF21A_HUMAN
θ value	0.00509761 (rank : 82)	NC score	0.274208 (rank : 67)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	75
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MLL3_HUMAN
θ value	0.00665767 (rank : 83)	NC score	0.242310 (rank : 85)
Query Neighborhood Hits	217	Target Neighborhood Hits	1644	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST4_HUMAN
θ value	0.00665767 (rank : 84)	NC score	0.235286 (rank : 92)
Query Neighborhood Hits	217	Target Neighborhood Hits	671	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	0.00665767 (rank : 85)	NC score	0.240315 (rank : 88)
Query Neighborhood Hits	217	Target Neighborhood Hits	416	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21A_MOUSE
θ value	0.00665767 (rank : 86)	NC score	0.274998 (rank : 66)
Query Neighborhood Hits	217	Target Neighborhood Hits	285	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

NSD1_HUMAN
θ value	0.00869519 (rank : 87)	NC score	0.237120 (rank : 91)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	84
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0.00869519 (rank : 88)	NC score	0.240959 (rank : 87)
Query Neighborhood Hits	217	Target Neighborhood Hits	472	Shared Neighborhood Hits	93
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

EPC2_HUMAN
θ value	0.0193708 (rank : 89)	NC score	0.153338 (rank : 122)
Query Neighborhood Hits	217	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

EPC2_MOUSE
θ value	0.0193708 (rank : 90)	NC score	0.153594 (rank : 121)
Query Neighborhood Hits	217	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

HRX_HUMAN
θ value	0.0193708 (rank : 91)	NC score	0.232669 (rank : 94)
Query Neighborhood Hits	217	Target Neighborhood Hits	825	Shared Neighborhood Hits	120
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL2_HUMAN
θ value	0.0330416 (rank : 92)	NC score	0.246510 (rank : 81)
Query Neighborhood Hits	217	Target Neighborhood Hits	1788	Shared Neighborhood Hits	142
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NFH_MOUSE
θ value	0.0330416 (rank : 93)	NC score	0.063705 (rank : 154)
Query Neighborhood Hits	217	Target Neighborhood Hits	2247	Shared Neighborhood Hits	112
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAI1_HUMAN
θ value	0.0330416 (rank : 94)	NC score	0.164850 (rank : 120)
Query Neighborhood Hits	217	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RSF1_HUMAN
θ value	0.0330416 (rank : 95)	NC score	0.272465 (rank : 68)
Query Neighborhood Hits	217	Target Neighborhood Hits	539	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

UHRF2_MOUSE
θ value	0.0330416 (rank : 96)	NC score	0.196795 (rank : 105)
Query Neighborhood Hits	217	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

AIRE_HUMAN
θ value	0.0431538 (rank : 97)	NC score	0.339857 (rank : 55)
Query Neighborhood Hits	217	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PHF12_MOUSE
θ value	0.0431538 (rank : 98)	NC score	0.253060 (rank : 76)
Query Neighborhood Hits	217	Target Neighborhood Hits	172	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

REQU_HUMAN
θ value	0.0431538 (rank : 99)	NC score	0.252990 (rank : 77)
Query Neighborhood Hits	217	Target Neighborhood Hits	523	Shared Neighborhood Hits	71
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

DPF1_HUMAN
θ value	0.0563607 (rank : 100)	NC score	0.248958 (rank : 78)
Query Neighborhood Hits	217	Target Neighborhood Hits	136	Shared Neighborhood Hits	65
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PHF12_HUMAN
θ value	0.0563607 (rank : 101)	NC score	0.255262 (rank : 74)
Query Neighborhood Hits	217	Target Neighborhood Hits	174	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TXND2_HUMAN
θ value	0.0563607 (rank : 102)	NC score	0.081084 (rank : 139)
Query Neighborhood Hits	217	Target Neighborhood Hits	793	Shared Neighborhood Hits	68
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CSPG2_HUMAN
θ value	0.0736092 (rank : 103)	NC score	0.011709 (rank : 238)
Query Neighborhood Hits	217	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MTF2_HUMAN
θ value	0.0736092 (rank : 104)	NC score	0.296500 (rank : 65)
Query Neighborhood Hits	217	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	0.0736092 (rank : 105)	NC score	0.300956 (rank : 64)
Query Neighborhood Hits	217	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

RAI1_MOUSE
θ value	0.0736092 (rank : 106)	NC score	0.176669 (rank : 113)
Query Neighborhood Hits	217	Target Neighborhood Hits	344	Shared Neighborhood Hits	55
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_MOUSE
θ value	0.0736092 (rank : 107)	NC score	0.248813 (rank : 79)
Query Neighborhood Hits	217	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

LR37A_HUMAN
θ value	0.0961366 (rank : 108)	NC score	0.042992 (rank : 183)
Query Neighborhood Hits	217	Target Neighborhood Hits	720	Shared Neighborhood Hits	40
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

KIF14_HUMAN
θ value	0.125558 (rank : 109)	NC score	0.014665 (rank : 229)
Query Neighborhood Hits	217	Target Neighborhood Hits	732	Shared Neighborhood Hits	30
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

IWS1_MOUSE
θ value	0.163984 (rank : 110)	NC score	0.086484 (rank : 136)
Query Neighborhood Hits	217	Target Neighborhood Hits	1258	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UHRF2_HUMAN
θ value	0.163984 (rank : 111)	NC score	0.180414 (rank : 111)
Query Neighborhood Hits	217	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

FA13C_MOUSE
θ value	0.21417 (rank : 112)	NC score	0.027714 (rank : 195)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

TEKT1_MOUSE
θ value	0.279714 (rank : 113)	NC score	0.025047 (rank : 203)
Query Neighborhood Hits	217	Target Neighborhood Hits	399	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TP53B_MOUSE
θ value	0.279714 (rank : 114)	NC score	0.065068 (rank : 152)
Query Neighborhood Hits	217	Target Neighborhood Hits	644	Shared Neighborhood Hits	54
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CJ078_MOUSE
θ value	0.365318 (rank : 115)	NC score	0.065416 (rank : 151)
Query Neighborhood Hits	217	Target Neighborhood Hits	559	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ZN592_HUMAN
θ value	0.365318 (rank : 116)	NC score	0.002717 (rank : 265)
Query Neighborhood Hits	217	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

K1333_MOUSE
θ value	0.47712 (rank : 117)	NC score	0.143599 (rank : 123)
Query Neighborhood Hits	217	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

TCF20_HUMAN
θ value	0.47712 (rank : 118)	NC score	0.127231 (rank : 126)
Query Neighborhood Hits	217	Target Neighborhood Hits	323	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TEKT1_HUMAN
θ value	0.47712 (rank : 119)	NC score	0.024879 (rank : 204)
Query Neighborhood Hits	217	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

AKAP9_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.022320 (rank : 209)
Query Neighborhood Hits	217	Target Neighborhood Hits	1710	Shared Neighborhood Hits	63
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CING_MOUSE
θ value	0.62314 (rank : 121)	NC score	0.014926 (rank : 227)
Query Neighborhood Hits	217	Target Neighborhood Hits	1432	Shared Neighborhood Hits	51
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

IWS1_HUMAN
θ value	0.62314 (rank : 122)	NC score	0.086911 (rank : 135)
Query Neighborhood Hits	217	Target Neighborhood Hits	1241	Shared Neighborhood Hits	87
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAD1A_HUMAN
θ value	0.62314 (rank : 123)	NC score	0.265995 (rank : 70)
Query Neighborhood Hits	217	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

NP1L2_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.016684 (rank : 223)
Query Neighborhood Hits	217	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULW6, Q8TAN6	Gene names	NAP1L2, BPX
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

PDZD2_HUMAN
θ value	0.62314 (rank : 125)	NC score	0.025913 (rank : 198)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	39
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RBP2_MOUSE
θ value	0.62314 (rank : 126)	NC score	0.023339 (rank : 208)
Query Neighborhood Hits	217	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RECQ5_HUMAN
θ value	0.62314 (rank : 127)	NC score	0.024443 (rank : 205)
Query Neighborhood Hits	217	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CP4F8_HUMAN
θ value	0.813845 (rank : 128)	NC score	0.004308 (rank : 262)
Query Neighborhood Hits	217	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P98187	Gene names	CYP4F8
Domain Architecture
Description	Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8).

MTSS1_HUMAN
θ value	0.813845 (rank : 129)	NC score	0.045466 (rank : 181)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	32
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

RBP2_HUMAN
θ value	0.813845 (rank : 130)	NC score	0.018411 (rank : 218)
Query Neighborhood Hits	217	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

MSH6_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.030803 (rank : 191)
Query Neighborhood Hits	217	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MTSS1_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.063581 (rank : 156)
Query Neighborhood Hits	217	Target Neighborhood Hits	592	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NID2_HUMAN
θ value	1.06291 (rank : 133)	NC score	0.004555 (rank : 260)
Query Neighborhood Hits	217	Target Neighborhood Hits	456	Shared Neighborhood Hits	10
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

OGFR_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.061726 (rank : 157)
Query Neighborhood Hits	217	Target Neighborhood Hits	1582	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RB15B_HUMAN
θ value	1.06291 (rank : 135)	NC score	0.011815 (rank : 237)
Query Neighborhood Hits	217	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

ZMY11_MOUSE
θ value	1.06291 (rank : 136)	NC score	0.201066 (rank : 103)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CEL_HUMAN
θ value	1.38821 (rank : 137)	NC score	0.025716 (rank : 199)
Query Neighborhood Hits	217	Target Neighborhood Hits	896	Shared Neighborhood Hits	44
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NEIL3_MOUSE
θ value	1.38821 (rank : 138)	NC score	0.020826 (rank : 214)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TCAL5_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.044291 (rank : 182)
Query Neighborhood Hits	217	Target Neighborhood Hits	806	Shared Neighborhood Hits	47
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ASPP1_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.022296 (rank : 210)
Query Neighborhood Hits	217	Target Neighborhood Hits	1244	Shared Neighborhood Hits	67
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CNOT3_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.031889 (rank : 190)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

K1802_MOUSE
θ value	1.81305 (rank : 142)	NC score	0.038544 (rank : 185)
Query Neighborhood Hits	217	Target Neighborhood Hits	1596	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MSH6_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.036075 (rank : 187)
Query Neighborhood Hits	217	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

PDE1C_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.007270 (rank : 249)
Query Neighborhood Hits	217	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PKHA6_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.016677 (rank : 224)
Query Neighborhood Hits	217	Target Neighborhood Hits	556	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

STK10_HUMAN
θ value	1.81305 (rank : 146)	NC score	0.002700 (rank : 266)
Query Neighborhood Hits	217	Target Neighborhood Hits	1921	Shared Neighborhood Hits	65
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

UHRF1_MOUSE
θ value	1.81305 (rank : 147)	NC score	0.165415 (rank : 119)
Query Neighborhood Hits	217	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ZMY11_HUMAN
θ value	1.81305 (rank : 148)	NC score	0.190266 (rank : 107)
Query Neighborhood Hits	217	Target Neighborhood Hits	201	Shared Neighborhood Hits	79
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

CLCN1_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.009000 (rank : 246)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

MRCKA_HUMAN
θ value	2.36792 (rank : 150)	NC score	-0.002099 (rank : 268)
Query Neighborhood Hits	217	Target Neighborhood Hits	1999	Shared Neighborhood Hits	42
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

P85A_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.005386 (rank : 257)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	14
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PR285_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.013120 (rank : 232)
Query Neighborhood Hits	217	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

RHG25_MOUSE
θ value	2.36792 (rank : 153)	NC score	0.012964 (rank : 233)
Query Neighborhood Hits	217	Target Neighborhood Hits	492	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TXLNB_MOUSE
θ value	2.36792 (rank : 154)	NC score	0.021288 (rank : 211)
Query Neighborhood Hits	217	Target Neighborhood Hits	640	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

CLSPN_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.023911 (rank : 207)
Query Neighborhood Hits	217	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CTRO_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.005379 (rank : 258)
Query Neighborhood Hits	217	Target Neighborhood Hits	2344	Shared Neighborhood Hits	70
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

JAD1D_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.268719 (rank : 69)
Query Neighborhood Hits	217	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

M3K1_MOUSE
θ value	3.0926 (rank : 158)	NC score	-0.003704 (rank : 269)
Query Neighborhood Hits	217	Target Neighborhood Hits	952	Shared Neighborhood Hits	13
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

RTN1_HUMAN
θ value	3.0926 (rank : 159)	NC score	0.027614 (rank : 197)
Query Neighborhood Hits	217	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

SO4A1_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.005789 (rank : 253)
Query Neighborhood Hits	217	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

TCF20_MOUSE
θ value	3.0926 (rank : 161)	NC score	0.117746 (rank : 129)
Query Neighborhood Hits	217	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

AL2S4_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.027701 (rank : 196)
Query Neighborhood Hits	217	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

DGKE_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.010500 (rank : 241)
Query Neighborhood Hits	217	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

EHMT2_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.020116 (rank : 215)
Query Neighborhood Hits	217	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GOG8A_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.011986 (rank : 236)
Query Neighborhood Hits	217	Target Neighborhood Hits	635	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

K0056_HUMAN
θ value	4.03905 (rank : 166)	NC score	0.019488 (rank : 216)
Query Neighborhood Hits	217	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

NCOR2_MOUSE
θ value	4.03905 (rank : 167)	NC score	0.034467 (rank : 189)
Query Neighborhood Hits	217	Target Neighborhood Hits	790	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NEIL1_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.016524 (rank : 225)
Query Neighborhood Hits	217	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

NOC3L_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.012663 (rank : 234)
Query Neighborhood Hits	217	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

TM119_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.017336 (rank : 221)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

UBE1L_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.009035 (rank : 245)
Query Neighborhood Hits	217	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

ZFP95_HUMAN
θ value	4.03905 (rank : 172)	NC score	-0.005817 (rank : 271)
Query Neighborhood Hits	217	Target Neighborhood Hits	775	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

ADDA_MOUSE
θ value	5.27518 (rank : 173)	NC score	0.014059 (rank : 230)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CCD41_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.018704 (rank : 217)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CE016_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.012265 (rank : 235)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BRJ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16 homolog.

CO5A1_MOUSE
θ value	5.27518 (rank : 176)	NC score	0.010436 (rank : 242)
Query Neighborhood Hits	217	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

DIDO1_HUMAN
θ value	5.27518 (rank : 177)	NC score	0.075150 (rank : 140)
Query Neighborhood Hits	217	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EEA1_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.014765 (rank : 228)
Query Neighborhood Hits	217	Target Neighborhood Hits	1796	Shared Neighborhood Hits	67
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EXO1_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.020916 (rank : 213)
Query Neighborhood Hits	217	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

HKR3_HUMAN
θ value	5.27518 (rank : 180)	NC score	-0.005696 (rank : 270)
Query Neighborhood Hits	217	Target Neighborhood Hits	839	Shared Neighborhood Hits	12
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

IQGA1_HUMAN
θ value	5.27518 (rank : 181)	NC score	0.005828 (rank : 252)
Query Neighborhood Hits	217	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

K1333_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.105680 (rank : 133)
Query Neighborhood Hits	217	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

KCNT1_MOUSE
θ value	5.27518 (rank : 183)	NC score	0.008858 (rank : 247)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

NEST_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.025587 (rank : 200)
Query Neighborhood Hits	217	Target Neighborhood Hits	1305	Shared Neighborhood Hits	56
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PCLO_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.051256 (rank : 171)
Query Neighborhood Hits	217	Target Neighborhood Hits	2275	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RTN4_MOUSE
θ value	5.27518 (rank : 186)	NC score	0.036185 (rank : 186)
Query Neighborhood Hits	217	Target Neighborhood Hits	341	Shared Neighborhood Hits	38
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

ST2B1_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.004802 (rank : 259)
Query Neighborhood Hits	217	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

SYTL2_MOUSE
θ value	5.27518 (rank : 188)	NC score	0.009046 (rank : 244)
Query Neighborhood Hits	217	Target Neighborhood Hits	253	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

UHRF1_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.166401 (rank : 118)
Query Neighborhood Hits	217	Target Neighborhood Hits	272	Shared Neighborhood Hits	59
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

USP9Y_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.003628 (rank : 264)
Query Neighborhood Hits	217	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

ARHGG_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.002518 (rank : 267)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CTGE5_MOUSE
θ value	6.88961 (rank : 192)	NC score	0.013227 (rank : 231)
Query Neighborhood Hits	217	Target Neighborhood Hits	928	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DMP1_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.051016 (rank : 175)
Query Neighborhood Hits	217	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DNMT1_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.024267 (rank : 206)
Query Neighborhood Hits	217	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

GRIPE_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.006506 (rank : 251)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

MINT_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.041492 (rank : 184)
Query Neighborhood Hits	217	Target Neighborhood Hits	1291	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OPTN_MOUSE
θ value	6.88961 (rank : 197)	NC score	0.018262 (rank : 220)
Query Neighborhood Hits	217	Target Neighborhood Hits	1120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PI5PA_HUMAN
θ value	6.88961 (rank : 198)	NC score	0.025578 (rank : 201)
Query Neighborhood Hits	217	Target Neighborhood Hits	749	Shared Neighborhood Hits	40
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

STAC3_HUMAN
θ value	6.88961 (rank : 199)	NC score	0.005532 (rank : 256)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ANK3_HUMAN
θ value	8.99809 (rank : 200)	NC score	0.004530 (rank : 261)
Query Neighborhood Hits	217	Target Neighborhood Hits	853	Shared Neighborhood Hits	45
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR11_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.018266 (rank : 219)
Query Neighborhood Hits	217	Target Neighborhood Hits	1289	Shared Neighborhood Hits	68
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CCD27_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.005779 (rank : 254)
Query Neighborhood Hits	217	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CDN1C_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.030197 (rank : 193)
Query Neighborhood Hits	217	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

DGKE_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.015613 (rank : 226)
Query Neighborhood Hits	217	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

EEA1_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.010228 (rank : 243)
Query Neighborhood Hits	217	Target Neighborhood Hits	1637	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GTSE1_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.025197 (rank : 202)
Query Neighborhood Hits	217	Target Neighborhood Hits	245	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

HDAC7_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.004291 (rank : 263)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

ICAL_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.030775 (rank : 192)
Query Neighborhood Hits	217	Target Neighborhood Hits	275	Shared Neighborhood Hits	32
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

MAVS_MOUSE
θ value	8.99809 (rank : 209)	NC score	0.016939 (rank : 222)
Query Neighborhood Hits	217	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

OPTN_HUMAN
θ value	8.99809 (rank : 210)	NC score	0.010997 (rank : 239)
Query Neighborhood Hits	217	Target Neighborhood Hits	827	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PHC1_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.021098 (rank : 212)
Query Neighborhood Hits	217	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

PI3R5_MOUSE
θ value	8.99809 (rank : 212)	NC score	0.006535 (rank : 250)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

RGS3_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.036021 (rank : 188)
Query Neighborhood Hits	217	Target Neighborhood Hits	1375	Shared Neighborhood Hits	68
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RTN4_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.029473 (rank : 194)
Query Neighborhood Hits	217	Target Neighborhood Hits	357	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TE2IP_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.010581 (rank : 240)
Query Neighborhood Hits	217	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

VATB1_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.005625 (rank : 255)
Query Neighborhood Hits	217	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P15313	Gene names	ATP6V1B1, ATP6B1, VATB, VPP3
Domain Architecture
Description	Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) (V- ATPase B1 subunit) (Vacuolar proton pump B isoform 1) (Endomembrane proton pump 58 kDa subunit).

YYAP1_HUMAN
θ value	8.99809 (rank : 217)	NC score	0.007774 (rank : 248)
Query Neighborhood Hits	217	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

ATRX_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.066823 (rank : 147)
Query Neighborhood Hits	217	Target Neighborhood Hits	842	Shared Neighborhood Hits	82
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.064733 (rank : 153)
Query Neighborhood Hits	217	Target Neighborhood Hits	682	Shared Neighborhood Hits	72
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BSN_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.052929 (rank : 166)
Query Neighborhood Hits	217	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CHD1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.051208 (rank : 173)
Query Neighborhood Hits	217	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.051015 (rank : 176)
Query Neighborhood Hits	217	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.052510 (rank : 167)
Query Neighborhood Hits	217	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.054763 (rank : 163)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.050821 (rank : 178)
Query Neighborhood Hits	217	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.050244 (rank : 180)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CXCC1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.052097 (rank : 168)
Query Neighborhood Hits	217	Target Neighborhood Hits	143	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DPF3_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.055006 (rank : 162)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EP400_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.051574 (rank : 170)
Query Neighborhood Hits	217	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.054754 (rank : 164)
Query Neighborhood Hits	217	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.051826 (rank : 169)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

ING1_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.051253 (rank : 172)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING3_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.082030 (rank : 138)
Query Neighborhood Hits	217	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.084213 (rank : 137)
Query Neighborhood Hits	217	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING4_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.066738 (rank : 148)
Query Neighborhood Hits	217	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.065781 (rank : 150)
Query Neighborhood Hits	217	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

JAD1C_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.246996 (rank : 80)
Query Neighborhood Hits	217	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.246455 (rank : 82)
Query Neighborhood Hits	217	Target Neighborhood Hits	164	Shared Neighborhood Hits	70
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.243079 (rank : 84)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	73
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JARD2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.104032 (rank : 134)
Query Neighborhood Hits	217	Target Neighborhood Hits	119	Shared Neighborhood Hits	13
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.108071 (rank : 131)
Query Neighborhood Hits	217	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3D_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.238247 (rank : 90)
Query Neighborhood Hits	217	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.238367 (rank : 89)
Query Neighborhood Hits	217	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

LY10_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.188559 (rank : 109)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	73
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MDC1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.058332 (rank : 160)
Query Neighborhood Hits	217	Target Neighborhood Hits	1446	Shared Neighborhood Hits	78
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.065898 (rank : 149)
Query Neighborhood Hits	217	Target Neighborhood Hits	998	Shared Neighborhood Hits	78
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NACAM_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.063634 (rank : 155)
Query Neighborhood Hits	217	Target Neighborhood Hits	1866	Shared Neighborhood Hits	90
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NIPBL_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.074815 (rank : 141)
Query Neighborhood Hits	217	Target Neighborhood Hits	1311	Shared Neighborhood Hits	85
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCLO_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.050757 (rank : 179)
Query Neighborhood Hits	217	Target Neighborhood Hits	2046	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PF21B_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.177091 (rank : 112)
Query Neighborhood Hits	217	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.174618 (rank : 114)
Query Neighborhood Hits	217	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF11_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.169608 (rank : 116)
Query Neighborhood Hits	217	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF20_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.071962 (rank : 144)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.072141 (rank : 143)
Query Neighborhood Hits	217	Target Neighborhood Hits	513	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF22_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.074143 (rank : 142)
Query Neighborhood Hits	217	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.106934 (rank : 132)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF6_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.125694 (rank : 127)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.114504 (rank : 130)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

RGS3_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.051059 (rank : 174)
Query Neighborhood Hits	217	Target Neighborhood Hits	1621	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SELPL_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.050984 (rank : 177)
Query Neighborhood Hits	217	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SET1A_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.067348 (rank : 146)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	53
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SON_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.059821 (rank : 158)
Query Neighborhood Hits	217	Target Neighborhood Hits	1568	Shared Neighborhood Hits	85
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SP110_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.118191 (rank : 128)
Query Neighborhood Hits	217	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SRRM1_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.053790 (rank : 165)
Query Neighborhood Hits	217	Target Neighborhood Hits	966	Shared Neighborhood Hits	67
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.058090 (rank : 161)
Query Neighborhood Hits	217	Target Neighborhood Hits	1470	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TAF3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.133070 (rank : 124)
Query Neighborhood Hits	217	Target Neighborhood Hits	568	Shared Neighborhood Hits	83
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.127623 (rank : 125)
Query Neighborhood Hits	217	Target Neighborhood Hits	463	Shared Neighborhood Hits	74
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TGON2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.067914 (rank : 145)
Query Neighborhood Hits	217	Target Neighborhood Hits	1037	Shared Neighborhood Hits	73
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1B_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.195428 (rank : 106)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	63
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.200701 (rank : 104)
Query Neighborhood Hits	217	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.058670 (rank : 159)
Query Neighborhood Hits	217	Target Neighborhood Hits	828	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

BRPF3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	217	Target Neighborhood Hits	217	Shared Neighborhood Hits	217
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRD1_HUMAN
NC score	0.977851 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	217	Target Neighborhood Hits	188	Shared Neighborhood Hits	122
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
NC score	0.959212 (rank : 3)	θ value	8.0589e-150 (rank : 3)
Query Neighborhood Hits	217	Target Neighborhood Hits	259	Shared Neighborhood Hits	124
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE3_MOUSE
NC score	0.808399 (rank : 4)	θ value	1.2784e-54 (rank : 6)
Query Neighborhood Hits	217	Target Neighborhood Hits	174	Shared Neighborhood Hits	88
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE1_HUMAN
NC score	0.806292 (rank : 5)	θ value	1.51013e-55 (rank : 5)
Query Neighborhood Hits	217	Target Neighborhood Hits	140	Shared Neighborhood Hits	83
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.805278 (rank : 6)	θ value	1.36585e-56 (rank : 4)
Query Neighborhood Hits	217	Target Neighborhood Hits	160	Shared Neighborhood Hits	83
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
NC score	0.804820 (rank : 7)	θ value	8.02596e-49 (rank : 7)
Query Neighborhood Hits	217	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
NC score	0.798375 (rank : 8)	θ value	1.97686e-47 (rank : 8)
Query Neighborhood Hits	217	Target Neighborhood Hits	199	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

AF17_HUMAN
NC score	0.781998 (rank : 9)	θ value	4.88048e-38 (rank : 10)
Query Neighborhood Hits	217	Target Neighborhood Hits	230	Shared Neighborhood Hits	64
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

JADE2_MOUSE
NC score	0.759883 (rank : 10)	θ value	1.67352e-46 (rank : 9)
Query Neighborhood Hits	217	Target Neighborhood Hits	560	Shared Neighborhood Hits	105
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

AF10_MOUSE
NC score	0.752409 (rank : 11)	θ value	1.85459e-37 (rank : 12)
Query Neighborhood Hits	217	Target Neighborhood Hits	182	Shared Neighborhood Hits	61
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.748846 (rank : 12)	θ value	1.85459e-37 (rank : 11)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

PHF14_MOUSE
NC score	0.712236 (rank : 13)	θ value	1.62847e-25 (rank : 13)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	93
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.700383 (rank : 14)	θ value	3.62785e-25 (rank : 15)
Query Neighborhood Hits	217	Target Neighborhood Hits	447	Shared Neighborhood Hits	104
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

JHD3B_MOUSE
NC score	0.572642 (rank : 15)	θ value	4.73814e-25 (rank : 16)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_HUMAN
NC score	0.572381 (rank : 16)	θ value	3.62785e-25 (rank : 14)
Query Neighborhood Hits	217	Target Neighborhood Hits	128	Shared Neighborhood Hits	46
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3A_MOUSE
NC score	0.564907 (rank : 17)	θ value	1.99067e-23 (rank : 19)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_MOUSE
NC score	0.564148 (rank : 18)	θ value	3.07116e-24 (rank : 17)
Query Neighborhood Hits	217	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
NC score	0.563123 (rank : 19)	θ value	1.99067e-23 (rank : 18)
Query Neighborhood Hits	217	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
NC score	0.559958 (rank : 20)	θ value	9.87957e-23 (rank : 20)
Query Neighborhood Hits	217	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

BRD7_HUMAN
NC score	0.496036 (rank : 21)	θ value	6.85773e-16 (rank : 22)
Query Neighborhood Hits	217	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD9_HUMAN
NC score	0.494914 (rank : 22)	θ value	1.42992e-13 (rank : 23)
Query Neighborhood Hits	217	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
NC score	0.491142 (rank : 23)	θ value	1.86753e-13 (rank : 24)
Query Neighborhood Hits	217	Target Neighborhood Hits	84	Shared Neighborhood Hits	50
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD7_MOUSE
NC score	0.490125 (rank : 24)	θ value	5.25075e-16 (rank : 21)
Query Neighborhood Hits	217	Target Neighborhood Hits	141	Shared Neighborhood Hits	53
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BAZ1A_HUMAN
NC score	0.451922 (rank : 25)	θ value	5.81887e-07 (rank : 51)
Query Neighborhood Hits	217	Target Neighborhood Hits	693	Shared Neighborhood Hits	116
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_MOUSE
NC score	0.451716 (rank : 26)	θ value	2.21117e-06 (rank : 54)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2B_HUMAN
NC score	0.445781 (rank : 27)	θ value	5.62301e-10 (rank : 27)
Query Neighborhood Hits	217	Target Neighborhood Hits	803	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_HUMAN
NC score	0.435106 (rank : 28)	θ value	1.99992e-07 (rank : 44)
Query Neighborhood Hits	217	Target Neighborhood Hits	780	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.429890 (rank : 29)	θ value	2.61198e-07 (rank : 45)
Query Neighborhood Hits	217	Target Neighborhood Hits	744	Shared Neighborhood Hits	121
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BPTF_HUMAN
NC score	0.426207 (rank : 30)	θ value	2.79066e-09 (rank : 29)
Query Neighborhood Hits	217	Target Neighborhood Hits	786	Shared Neighborhood Hits	120
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BAZ1B_HUMAN
NC score	0.419436 (rank : 31)	θ value	2.88788e-06 (rank : 55)
Query Neighborhood Hits	217	Target Neighborhood Hits	701	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

PCAF_HUMAN
NC score	0.418659 (rank : 32)	θ value	8.97725e-08 (rank : 40)
Query Neighborhood Hits	217	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRD2_HUMAN
NC score	0.405106 (rank : 33)	θ value	1.38499e-08 (rank : 34)
Query Neighborhood Hits	217	Target Neighborhood Hits	242	Shared Neighborhood Hits	61
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

GCNL2_HUMAN
NC score	0.403440 (rank : 34)	θ value	4.76016e-09 (rank : 31)
Query Neighborhood Hits	217	Target Neighborhood Hits	159	Shared Neighborhood Hits	54
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
NC score	0.400503 (rank : 35)	θ value	1.06045e-08 (rank : 33)
Query Neighborhood Hits	217	Target Neighborhood Hits	146	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

TAF1_HUMAN
NC score	0.399627 (rank : 36)	θ value	2.79066e-09 (rank : 30)
Query Neighborhood Hits	217	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BRD8_HUMAN
NC score	0.397221 (rank : 37)	θ value	5.26297e-08 (rank : 36)
Query Neighborhood Hits	217	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

TAF1L_HUMAN
NC score	0.389880 (rank : 38)	θ value	6.21693e-09 (rank : 32)
Query Neighborhood Hits	217	Target Neighborhood Hits	144	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

BRD3_MOUSE
NC score	0.387631 (rank : 39)	θ value	3.41135e-07 (rank : 48)
Query Neighborhood Hits	217	Target Neighborhood Hits	402	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CECR2_HUMAN
NC score	0.385788 (rank : 40)	θ value	1.63604e-09 (rank : 28)
Query Neighborhood Hits	217	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BRD3_HUMAN
NC score	0.384782 (rank : 41)	θ value	1.29631e-06 (rank : 53)
Query Neighborhood Hits	217	Target Neighborhood Hits	369	Shared Neighborhood Hits	65
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

TIF1A_MOUSE
NC score	0.381083 (rank : 42)	θ value	1.17247e-07 (rank : 43)
Query Neighborhood Hits	217	Target Neighborhood Hits	307	Shared Neighborhood Hits	101
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.380073 (rank : 43)	θ value	1.80886e-08 (rank : 35)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	99
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

PKCB1_HUMAN
NC score	0.378843 (rank : 44)	θ value	6.43352e-06 (rank : 59)
Query Neighborhood Hits	217	Target Neighborhood Hits	488	Shared Neighborhood Hits	115
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

BRD8_MOUSE
NC score	0.378661 (rank : 45)	θ value	5.26297e-08 (rank : 37)
Query Neighborhood Hits	217	Target Neighborhood Hits	422	Shared Neighborhood Hits	75
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRDT_MOUSE
NC score	0.373832 (rank : 46)	θ value	3.77169e-06 (rank : 56)
Query Neighborhood Hits	217	Target Neighborhood Hits	243	Shared Neighborhood Hits	57
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRDT_HUMAN
NC score	0.372006 (rank : 47)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	217	Target Neighborhood Hits	280	Shared Neighborhood Hits	62
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

PHF10_HUMAN
NC score	0.370741 (rank : 48)	θ value	5.81887e-07 (rank : 52)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.368171 (rank : 49)	θ value	3.41135e-07 (rank : 50)
Query Neighborhood Hits	217	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PB1_HUMAN
NC score	0.367615 (rank : 50)	θ value	1.43324e-05 (rank : 61)
Query Neighborhood Hits	217	Target Neighborhood Hits	261	Shared Neighborhood Hits	55
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BRD4_MOUSE
NC score	0.365430 (rank : 51)	θ value	8.97725e-08 (rank : 39)
Query Neighborhood Hits	217	Target Neighborhood Hits	845	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD4_HUMAN
NC score	0.363523 (rank : 52)	θ value	1.17247e-07 (rank : 41)
Query Neighborhood Hits	217	Target Neighborhood Hits	851	Shared Neighborhood Hits	84
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TRI66_HUMAN
NC score	0.354540 (rank : 53)	θ value	0.000158464 (rank : 64)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	107
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
NC score	0.351135 (rank : 54)	θ value	0.000158464 (rank : 65)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	110
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

AIRE_HUMAN
NC score	0.339857 (rank : 55)	θ value	0.0431538 (rank : 97)
Query Neighborhood Hits	217	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.331009 (rank : 56)	θ value	0.000786445 (rank : 70)
Query Neighborhood Hits	217	Target Neighborhood Hits	196	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TIF1G_MOUSE
NC score	0.328234 (rank : 57)	θ value	1.43324e-05 (rank : 62)
Query Neighborhood Hits	217	Target Neighborhood Hits	498	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

EP300_HUMAN
NC score	0.328013 (rank : 58)	θ value	2.61198e-07 (rank : 47)
Query Neighborhood Hits	217	Target Neighborhood Hits	821	Shared Neighborhood Hits	91
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

TIF1G_HUMAN
NC score	0.327445 (rank : 59)	θ value	2.44474e-05 (rank : 63)
Query Neighborhood Hits	217	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

CBP_HUMAN
NC score	0.325797 (rank : 60)	θ value	3.41135e-07 (rank : 49)
Query Neighborhood Hits	217	Target Neighborhood Hits	941	Shared Neighborhood Hits	86
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
NC score	0.313547 (rank : 61)	θ value	1.17247e-07 (rank : 42)
Query Neighborhood Hits	217	Target Neighborhood Hits	1051	Shared Neighborhood Hits	90
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PHF1_HUMAN
NC score	0.309486 (rank : 62)	θ value	0.00035302 (rank : 66)
Query Neighborhood Hits	217	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.309206 (rank : 63)	θ value	0.00035302 (rank : 67)
Query Neighborhood Hits	217	Target Neighborhood Hits	116	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

MTF2_MOUSE
NC score	0.300956 (rank : 64)	θ value	0.0736092 (rank : 105)
Query Neighborhood Hits	217	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_HUMAN
NC score	0.296500 (rank : 65)	θ value	0.0736092 (rank : 104)
Query Neighborhood Hits	217	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PF21A_MOUSE
NC score	0.274998 (rank : 66)	θ value	0.00665767 (rank : 86)
Query Neighborhood Hits	217	Target Neighborhood Hits	285	Shared Neighborhood Hits	77
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.274208 (rank : 67)	θ value	0.00509761 (rank : 82)
Query Neighborhood Hits	217	Target Neighborhood Hits	303	Shared Neighborhood Hits	75
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RSF1_HUMAN
NC score	0.272465 (rank : 68)	θ value	0.0330416 (rank : 95)
Query Neighborhood Hits	217	Target Neighborhood Hits	539	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

JAD1D_HUMAN
NC score	0.268719 (rank : 69)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	217	Target Neighborhood Hits	147	Shared Neighborhood Hits	74
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1A_HUMAN
NC score	0.265995 (rank : 70)	θ value	0.62314 (rank : 123)
Query Neighborhood Hits	217	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

MLL3_MOUSE
NC score	0.256864 (rank : 71)	θ value	0.00175202 (rank : 79)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	129
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL4_HUMAN
NC score	0.255948 (rank : 72)	θ value	0.00390308 (rank : 81)
Query Neighborhood Hits	217	Target Neighborhood Hits	722	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

DPF1_MOUSE
NC score	0.255641 (rank : 73)	θ value	0.00390308 (rank : 80)
Query Neighborhood Hits	217	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PHF12_HUMAN
NC score	0.255262 (rank : 74)	θ value	0.0563607 (rank : 101)
Query Neighborhood Hits	217	Target Neighborhood Hits	174	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF7_MOUSE
NC score	0.254518 (rank : 75)	θ value	0.00102713 (rank : 74)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF12_MOUSE
NC score	0.253060 (rank : 76)	θ value	0.0431538 (rank : 98)
Query Neighborhood Hits	217	Target Neighborhood Hits	172	Shared Neighborhood Hits	66
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

REQU_HUMAN
NC score	0.252990 (rank : 77)	θ value	0.0431538 (rank : 99)
Query Neighborhood Hits	217	Target Neighborhood Hits	523	Shared Neighborhood Hits	71
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

DPF1_HUMAN
NC score	0.248958 (rank : 78)	θ value	0.0563607 (rank : 100)
Query Neighborhood Hits	217	Target Neighborhood Hits	136	Shared Neighborhood Hits	65
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_MOUSE
NC score	0.248813 (rank : 79)	θ value	0.0736092 (rank : 107)
Query Neighborhood Hits	217	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

JAD1C_HUMAN
NC score	0.246996 (rank : 80)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	217	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

MLL2_HUMAN
NC score	0.246510 (rank : 81)	θ value	0.0330416 (rank : 92)
Query Neighborhood Hits	217	Target Neighborhood Hits	1788	Shared Neighborhood Hits	142
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

JAD1C_MOUSE
NC score	0.246455 (rank : 82)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	217	Target Neighborhood Hits	164	Shared Neighborhood Hits	70
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

MYST3_HUMAN
NC score	0.244335 (rank : 83)	θ value	0.00102713 (rank : 72)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	109
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

JAD1D_MOUSE
NC score	0.243079 (rank : 84)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	73
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MLL3_HUMAN
NC score	0.242310 (rank : 85)	θ value	0.00665767 (rank : 83)
Query Neighborhood Hits	217	Target Neighborhood Hits	1644	Shared Neighborhood Hits	133
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST3_MOUSE
NC score	0.241952 (rank : 86)	θ value	0.00102713 (rank : 73)
Query Neighborhood Hits	217	Target Neighborhood Hits	688	Shared Neighborhood Hits	105
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NSD1_MOUSE
NC score	0.240959 (rank : 87)	θ value	0.00869519 (rank : 88)
Query Neighborhood Hits	217	Target Neighborhood Hits	472	Shared Neighborhood Hits	93
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MYST4_MOUSE
NC score	0.240315 (rank : 88)	θ value	0.00665767 (rank : 85)
Query Neighborhood Hits	217	Target Neighborhood Hits	416	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

JHD3D_MOUSE
NC score	0.238367 (rank : 89)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	217	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_HUMAN
NC score	0.238247 (rank : 90)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	217	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

NSD1_HUMAN
NC score	0.237120 (rank : 91)	θ value	0.00869519 (rank : 87)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	84
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MYST4_HUMAN
NC score	0.235286 (rank : 92)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	217	Target Neighborhood Hits	671	Shared Neighborhood Hits	102
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PHF7_HUMAN
NC score	0.232715 (rank : 93)	θ value	0.00134147 (rank : 75)
Query Neighborhood Hits	217	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

HRX_HUMAN
NC score	0.232669 (rank : 94)	θ value	0.0193708 (rank : 91)
Query Neighborhood Hits	217	Target Neighborhood Hits	825	Shared Neighborhood Hits	120
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ATAD2_HUMAN
NC score	0.223215 (rank : 95)	θ value	2.98157e-11 (rank : 25)
Query Neighborhood Hits	217	Target Neighborhood Hits	322	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
NC score	0.221181 (rank : 96)	θ value	1.133e-10 (rank : 26)
Query Neighborhood Hits	217	Target Neighborhood Hits	167	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BRWD1_HUMAN
NC score	0.211316 (rank : 97)	θ value	3.77169e-06 (rank : 57)
Query Neighborhood Hits	217	Target Neighborhood Hits	448	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRWD1_MOUSE
NC score	0.211227 (rank : 98)	θ value	2.61198e-07 (rank : 46)
Query Neighborhood Hits	217	Target Neighborhood Hits	478	Shared Neighborhood Hits	56
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CHD3_HUMAN
NC score	0.207031 (rank : 99)	θ value	0.000602161 (rank : 68)
Query Neighborhood Hits	217	Target Neighborhood Hits	397	Shared Neighborhood Hits	85
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
NC score	0.206215 (rank : 100)	θ value	0.000602161 (rank : 69)
Query Neighborhood Hits	217	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
NC score	0.204439 (rank : 101)	θ value	0.00175202 (rank : 76)
Query Neighborhood Hits	217	Target Neighborhood Hits	365	Shared Neighborhood Hits	90
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.204292 (rank : 102)	θ value	0.00175202 (rank : 77)
Query Neighborhood Hits	217	Target Neighborhood Hits	408	Shared Neighborhood Hits	94
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ZMY11_MOUSE
NC score	0.201066 (rank : 103)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

TIF1B_MOUSE
NC score	0.200701 (rank : 104)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	217	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

UHRF2_MOUSE
NC score	0.196795 (rank : 105)	θ value	0.0330416 (rank : 96)
Query Neighborhood Hits	217	Target Neighborhood Hits	275	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TIF1B_HUMAN
NC score	0.195428 (rank : 106)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	217	Target Neighborhood Hits	312	Shared Neighborhood Hits	63
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

ZMY11_HUMAN
NC score	0.190266 (rank : 107)	θ value	1.81305 (rank : 148)
Query Neighborhood Hits	217	Target Neighborhood Hits	201	Shared Neighborhood Hits	79
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

SMCA4_HUMAN
NC score	0.189418 (rank : 108)	θ value	6.87365e-08 (rank : 38)
Query Neighborhood Hits	217	Target Neighborhood Hits	597	Shared Neighborhood Hits	80
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

LY10_HUMAN
NC score	0.188559 (rank : 109)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	217	Target Neighborhood Hits	151	Shared Neighborhood Hits	73
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SMCA2_HUMAN
NC score	0.181815 (rank : 110)	θ value	4.92598e-06 (rank : 58)
Query Neighborhood Hits	217	Target Neighborhood Hits	503	Shared Neighborhood Hits	76
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

UHRF2_HUMAN
NC score	0.180414 (rank : 111)	θ value	0.163984 (rank : 111)
Query Neighborhood Hits	217	Target Neighborhood Hits	269	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

PF21B_HUMAN
NC score	0.177091 (rank : 112)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	217	Target Neighborhood Hits	197	Shared Neighborhood Hits	61
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RAI1_MOUSE
NC score	0.176669 (rank : 113)	θ value	0.0736092 (rank : 106)
Query Neighborhood Hits	217	Target Neighborhood Hits	344	Shared Neighborhood Hits	55
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PF21B_MOUSE
NC score	0.174618 (rank : 114)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	217	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

EPC1_HUMAN
NC score	0.172447 (rank : 115)	θ value	0.00175202 (rank : 78)
Query Neighborhood Hits	217	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H2F5, Q5VW54, Q5VW56, Q5VW58, Q8NAQ4, Q8NE21, Q96LF4, Q96RR6, Q9H7T7	Gene names	EPC1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

PHF11_HUMAN
NC score	0.169608 (rank : 116)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	217	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

EPC1_MOUSE
NC score	0.168938 (rank : 117)	θ value	0.00102713 (rank : 71)
Query Neighborhood Hits	217	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

UHRF1_HUMAN
NC score	0.166401 (rank : 118)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	217	Target Neighborhood Hits	272	Shared Neighborhood Hits	59
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
NC score	0.165415 (rank : 119)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	217	Target Neighborhood Hits	278	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RAI1_HUMAN
NC score	0.164850 (rank : 120)	θ value	0.0330416 (rank : 94)
Query Neighborhood Hits	217	Target Neighborhood Hits	360	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

EPC2_MOUSE
NC score	0.153594 (rank : 121)	θ value	0.0193708 (rank : 90)
Query Neighborhood Hits	217	Target Neighborhood Hits	59	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

EPC2_HUMAN
NC score	0.153338 (rank : 122)	θ value	0.0193708 (rank : 89)
Query Neighborhood Hits	217	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

K1333_MOUSE
NC score	0.143599 (rank : 123)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	217	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

TAF3_HUMAN
NC score	0.133070 (rank : 124)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	217	Target Neighborhood Hits	568	Shared Neighborhood Hits	83
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
NC score	0.127623 (rank : 125)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	217	Target Neighborhood Hits	463	Shared Neighborhood Hits	74
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCF20_HUMAN
NC score	0.127231 (rank : 126)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	217	Target Neighborhood Hits	323	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PHF6_HUMAN
NC score	0.125694 (rank : 127)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	217	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

SP110_HUMAN
NC score	0.118191 (rank : 128)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	217	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TCF20_MOUSE
NC score	0.117746 (rank : 129)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	217	Target Neighborhood Hits	396	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PHF6_MOUSE
NC score	0.114504 (rank : 130)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

JARD2_MOUSE
NC score	0.108071 (rank : 131)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	217	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PHF22_MOUSE
NC score	0.106934 (rank : 132)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

K1333_HUMAN
NC score	0.105680 (rank : 133)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	217	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

JARD2_HUMAN
NC score	0.104032 (rank : 134)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	217	Target Neighborhood Hits	119	Shared Neighborhood Hits	13
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

IWS1_HUMAN
NC score	0.086911 (rank : 135)	θ value	0.62314 (rank : 122)
Query Neighborhood Hits	217	Target Neighborhood Hits	1241	Shared Neighborhood Hits	87
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.086484 (rank : 136)	θ value	0.163984 (rank : 110)
Query Neighborhood Hits	217	Target Neighborhood Hits	1258	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ING3_MOUSE
NC score	0.084213 (rank : 137)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	217	Target Neighborhood Hits	177	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_HUMAN
NC score	0.082030 (rank : 138)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	217	Target Neighborhood Hits	178	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

TXND2_HUMAN
NC score	0.081084 (rank : 139)	θ value	0.0563607 (rank : 102)
Query Neighborhood Hits	217	Target Neighborhood Hits	793	Shared Neighborhood Hits	68
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

DIDO1_HUMAN
NC score	0.075150 (rank : 140)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	217	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

NIPBL_HUMAN
NC score	0.074815 (rank : 141)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	217	Target Neighborhood Hits	1311	Shared Neighborhood Hits	85
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHF22_HUMAN
NC score	0.074143 (rank : 142)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	217	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF20_MOUSE
NC score	0.072141 (rank : 143)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	217	Target Neighborhood Hits	513	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF20_HUMAN
NC score	0.071962 (rank : 144)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	217	Target Neighborhood Hits	394	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

TGON2_HUMAN
NC score	0.067914 (rank : 145)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	217	Target Neighborhood Hits	1037	Shared Neighborhood Hits	73
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SET1A_HUMAN
NC score	0.067348 (rank : 146)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	217	Target Neighborhood Hits	690	Shared Neighborhood Hits	53
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

ATRX_HUMAN
NC score	0.066823 (rank : 147)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	217	Target Neighborhood Hits	842	Shared Neighborhood Hits	82
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ING4_HUMAN
NC score	0.066738 (rank : 148)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	217	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

MDC1_MOUSE
NC score	0.065898 (rank : 149)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	217	Target Neighborhood Hits	998	Shared Neighborhood Hits	78
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ING4_MOUSE
NC score	0.065781 (rank : 150)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	217	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

CJ078_MOUSE
NC score	0.065416 (rank : 151)	θ value	0.365318 (rank : 115)
Query Neighborhood Hits	217	Target Neighborhood Hits	559	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

TP53B_MOUSE
NC score	0.065068 (rank : 152)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	217	Target Neighborhood Hits	644	Shared Neighborhood Hits	54
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATRX_MOUSE
NC score	0.064733 (rank : 153)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	217	Target Neighborhood Hits	682	Shared Neighborhood Hits	72
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

NFH_MOUSE
NC score	0.063705 (rank : 154)	θ value	0.0330416 (rank : 93)
Query Neighborhood Hits	217	Target Neighborhood Hits	2247	Shared Neighborhood Hits	112
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NACAM_MOUSE
NC score	0.063634 (rank : 155)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	217	Target Neighborhood Hits	1866	Shared Neighborhood Hits	90
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MTSS1_MOUSE
NC score	0.063581 (rank : 156)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	217	Target Neighborhood Hits	592	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

OGFR_HUMAN
NC score	0.061726 (rank : 157)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	217	Target Neighborhood Hits	1582	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SON_HUMAN
NC score	0.059821 (rank : 158)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	217	Target Neighborhood Hits	1568	Shared Neighborhood Hits	85
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TXND2_MOUSE
NC score	0.058670 (rank : 159)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	217	Target Neighborhood Hits	828	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MDC1_HUMAN
NC score	0.058332 (rank : 160)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	217	Target Neighborhood Hits	1446	Shared Neighborhood Hits	78
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SRRM2_MOUSE
NC score	0.058090 (rank : 161)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	217	Target Neighborhood Hits	1470	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

DPF3_MOUSE
NC score	0.055006 (rank : 162)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	217	Target Neighborhood Hits	327	Shared Neighborhood Hits	14
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

CHD6_HUMAN
NC score	0.054763 (rank : 163)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	217	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

EP400_MOUSE
NC score	0.054754 (rank : 164)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	217	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SRRM1_MOUSE
NC score	0.053790 (rank : 165)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	217	Target Neighborhood Hits	966	Shared Neighborhood Hits	67
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BSN_MOUSE
NC score	0.052929 (rank : 166)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	217	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CHD2_HUMAN
NC score	0.052510 (rank : 167)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	217	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CXCC1_HUMAN
NC score	0.052097 (rank : 168)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	217	Target Neighborhood Hits	143	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

ERCC6_HUMAN
NC score	0.051826 (rank : 169)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	217	Target Neighborhood Hits	247	Shared Neighborhood Hits	20
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

EP400_HUMAN
NC score	0.051574 (rank : 170)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	217	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PCLO_MOUSE
NC score	0.051256 (rank : 171)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	217	Target Neighborhood Hits	2275	Shared Neighborhood Hits	102
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ING1_HUMAN
NC score	0.051253 (rank : 172)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	217	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

CHD1_HUMAN
NC score	0.051208 (rank : 173)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	217	Target Neighborhood Hits	337	Shared Neighborhood Hits	26
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RGS3_MOUSE
NC score	0.051059 (rank : 174)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	217	Target Neighborhood Hits	1621	Shared Neighborhood Hits	79
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

DMP1_MOUSE
NC score	0.051016 (rank : 175)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	217	Target Neighborhood Hits	498	Shared Neighborhood Hits	36
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

CHD1_MOUSE
NC score	0.051015 (rank : 176)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	217	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SELPL_MOUSE
NC score	0.050984 (rank : 177)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	217	Target Neighborhood Hits	588	Shared Neighborhood Hits	50
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CHD9_HUMAN
NC score	0.050821 (rank : 178)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	217	Target Neighborhood Hits	343	Shared Neighborhood Hits	30
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

PCLO_HUMAN
NC score	0.050757 (rank : 179)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	217	Target Neighborhood Hits	2046	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CHD9_MOUSE
NC score	0.050244 (rank : 180)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	217	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

MTSS1_HUMAN
NC score	0.045466 (rank : 181)	θ value	0.813845 (rank : 129)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	32
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

TCAL5_HUMAN
NC score	0.044291 (rank : 182)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	217	Target Neighborhood Hits	806	Shared Neighborhood Hits	47
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

LR37A_HUMAN
NC score	0.042992 (rank : 183)	θ value	0.0961366 (rank : 108)
Query Neighborhood Hits	217	Target Neighborhood Hits	720	Shared Neighborhood Hits	40
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MINT_HUMAN
NC score	0.041492 (rank : 184)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	217	Target Neighborhood Hits	1291	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

K1802_MOUSE
NC score	0.038544 (rank : 185)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	217	Target Neighborhood Hits	1596	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RTN4_MOUSE
NC score	0.036185 (rank : 186)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	217	Target Neighborhood Hits	341	Shared Neighborhood Hits	38
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

MSH6_MOUSE
NC score	0.036075 (rank : 187)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	217	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

RGS3_HUMAN
NC score	0.036021 (rank : 188)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	217	Target Neighborhood Hits	1375	Shared Neighborhood Hits	68
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

NCOR2_MOUSE
NC score	0.034467 (rank : 189)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	217	Target Neighborhood Hits	790	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CNOT3_MOUSE
NC score	0.031889 (rank : 190)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	217	Target Neighborhood Hits	504	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MSH6_HUMAN
NC score	0.030803 (rank : 191)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	217	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

ICAL_HUMAN
NC score	0.030775 (rank : 192)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	217	Target Neighborhood Hits	275	Shared Neighborhood Hits	32
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

CDN1C_MOUSE
NC score	0.030197 (rank : 193)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	217	Target Neighborhood Hits	161	Shared Neighborhood Hits	22
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

RTN4_HUMAN
NC score	0.029473 (rank : 194)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	217	Target Neighborhood Hits	357	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

FA13C_MOUSE
NC score	0.027714 (rank : 195)	θ value	0.21417 (rank : 112)
Query Neighborhood Hits	217	Target Neighborhood Hits	79	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

AL2S4_MOUSE
NC score	0.027701 (rank : 196)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	217	Target Neighborhood Hits	193	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

RTN1_HUMAN
NC score	0.027614 (rank : 197)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	217	Target Neighborhood Hits	173	Shared Neighborhood Hits	24
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

PDZD2_HUMAN
NC score	0.025913 (rank : 198)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	217	Target Neighborhood Hits	772	Shared Neighborhood Hits	39
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CEL_HUMAN
NC score	0.025716 (rank : 199)	θ value	1.38821 (rank : 137)
Query Neighborhood Hits	217	Target Neighborhood Hits	896	Shared Neighborhood Hits	44
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NEST_HUMAN
NC score	0.025587 (rank : 200)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	217	Target Neighborhood Hits	1305	Shared Neighborhood Hits	56
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PI5PA_HUMAN
NC score	0.025578 (rank : 201)	θ value	6.88961 (rank : 198)
Query Neighborhood Hits	217	Target Neighborhood Hits	749	Shared Neighborhood Hits	40
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

GTSE1_MOUSE
NC score	0.025197 (rank : 202)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	217	Target Neighborhood Hits	245	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

TEKT1_MOUSE
NC score	0.025047 (rank : 203)	θ value	0.279714 (rank : 113)
Query Neighborhood Hits	217	Target Neighborhood Hits	399	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

TEKT1_HUMAN
NC score	0.024879 (rank : 204)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	217	Target Neighborhood Hits	289	Shared Neighborhood Hits	12
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

RECQ5_HUMAN
NC score	0.024443 (rank : 205)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	217	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

DNMT1_HUMAN
NC score	0.024267 (rank : 206)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	217	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

CLSPN_HUMAN
NC score	0.023911 (rank : 207)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	217	Target Neighborhood Hits	433	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

RBP2_MOUSE
NC score	0.023339 (rank : 208)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	217	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

AKAP9_HUMAN
NC score	0.022320 (rank : 209)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	217	Target Neighborhood Hits	1710	Shared Neighborhood Hits	63
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ASPP1_MOUSE
NC score	0.022296 (rank : 210)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	217	Target Neighborhood Hits	1244	Shared Neighborhood Hits	67
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TXLNB_MOUSE
NC score	0.021288 (rank : 211)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	217	Target Neighborhood Hits	640	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

PHC1_HUMAN
NC score	0.021098 (rank : 212)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	217	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

EXO1_HUMAN
NC score	0.020916 (rank : 213)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	217	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

NEIL3_MOUSE
NC score	0.020826 (rank : 214)	θ value	1.38821 (rank : 138)
Query Neighborhood Hits	217	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

EHMT2_MOUSE
NC score	0.020116 (rank : 215)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	217	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

K0056_HUMAN
NC score	0.019488 (rank : 216)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	217	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	P42695	Gene names	KIAA0056
Domain Architecture	No domain graphic available
Description	Protein KIAA0056.

CCD41_MOUSE
NC score	0.018704 (rank : 217)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	217	Target Neighborhood Hits	1399	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

RBP2_HUMAN
NC score	0.018411 (rank : 218)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	217	Target Neighborhood Hits	249	Shared Neighborhood Hits	12
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

ANR11_HUMAN
NC score	0.018266 (rank : 219)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	217	Target Neighborhood Hits	1289	Shared Neighborhood Hits	68
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

OPTN_MOUSE
NC score	0.018262 (rank : 220)	θ value	6.88961 (rank : 197)
Query Neighborhood Hits	217	Target Neighborhood Hits	1120	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TM119_HUMAN
NC score	0.017336 (rank : 221)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	217	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q4V9L6, Q6UXE5, Q8N2F5	Gene names	TMEM119
Domain Architecture	No domain graphic available
Description	Transmembrane protein 119 precursor.

MAVS_MOUSE
NC score	0.016939 (rank : 222)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	217	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

NP1L2_HUMAN
NC score	0.016684 (rank : 223)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	217	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULW6, Q8TAN6	Gene names	NAP1L2, BPX
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

PKHA6_HUMAN
NC score	0.016677 (rank : 224)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	217	Target Neighborhood Hits	556	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

NEIL1_MOUSE
NC score	0.016524 (rank : 225)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	217	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

DGKE_MOUSE
NC score	0.015613 (rank : 226)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	217	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

CING_MOUSE
NC score	0.014926 (rank : 227)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	217	Target Neighborhood Hits	1432	Shared Neighborhood Hits	51
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

EEA1_HUMAN
NC score	0.014765 (rank : 228)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	217	Target Neighborhood Hits	1796	Shared Neighborhood Hits	67
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KIF14_HUMAN
NC score	0.014665 (rank : 229)	θ value	0.125558 (rank : 109)
Query Neighborhood Hits	217	Target Neighborhood Hits	732	Shared Neighborhood Hits	30
SwissProt Accessions	Q15058	Gene names	KIF14, KIAA0042
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF14.

ADDA_MOUSE
NC score	0.014059 (rank : 230)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	217	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYC0, Q9JLE3	Gene names	Add1
Domain Architecture
Description	Alpha-adducin (Erythrocyte adducin subunit alpha).

CTGE5_MOUSE
NC score	0.013227 (rank : 231)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	217	Target Neighborhood Hits	928	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

PR285_HUMAN
NC score	0.013120 (rank : 232)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	217	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

RHG25_MOUSE
NC score	0.012964 (rank : 233)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	217	Target Neighborhood Hits	492	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

NOC3L_MOUSE
NC score	0.012663 (rank : 234)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	217	Target Neighborhood Hits	177	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VI84, Q9JKM3	Gene names	Noc3l, Ad24, Fad24
Domain Architecture	No domain graphic available
Description	Nucleolar complex protein 3 homolog (NOC3 protein homolog) (NOC3-like protein) (Nucleolar complex-associated protein 3-like protein) (Factor for adipocyte differentiation 24).

CE016_MOUSE
NC score	0.012265 (rank : 235)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BRJ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16 homolog.

GOG8A_HUMAN
NC score	0.011986 (rank : 236)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	217	Target Neighborhood Hits	635	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

RB15B_HUMAN
NC score	0.011815 (rank : 237)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	217	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

CSPG2_HUMAN
NC score	0.011709 (rank : 238)	θ value	0.0736092 (rank : 103)
Query Neighborhood Hits	217	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

OPTN_HUMAN
NC score	0.010997 (rank : 239)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	217	Target Neighborhood Hits	827	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

TE2IP_MOUSE
NC score	0.010581 (rank : 240)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	217	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

DGKE_HUMAN
NC score	0.010500 (rank : 241)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	217	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

CO5A1_MOUSE
NC score	0.010436 (rank : 242)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	217	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

EEA1_MOUSE
NC score	0.010228 (rank : 243)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	217	Target Neighborhood Hits	1637	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

SYTL2_MOUSE
NC score	0.009046 (rank : 244)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	217	Target Neighborhood Hits	253	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

UBE1L_HUMAN
NC score	0.009035 (rank : 245)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	217	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

CLCN1_HUMAN
NC score	0.009000 (rank : 246)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	217	Target Neighborhood Hits	89	Shared Neighborhood Hits	9
SwissProt Accessions	P35523	Gene names	CLCN1, CLC1
Domain Architecture
Description	Chloride channel protein, skeletal muscle (Chloride channel protein 1) (ClC-1).

KCNT1_MOUSE
NC score	0.008858 (rank : 247)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

YYAP1_HUMAN
NC score	0.007774 (rank : 248)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	217	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

PDE1C_MOUSE
NC score	0.007270 (rank : 249)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	217	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PI3R5_MOUSE
NC score	0.006535 (rank : 250)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	217	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SW28, Q3TU01, Q3UDZ2, Q8C215, Q8CGQ7	Gene names	Pik3r5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit).

GRIPE_HUMAN
NC score	0.006506 (rank : 251)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	217	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

IQGA1_HUMAN
NC score	0.005828 (rank : 252)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	217	Target Neighborhood Hits	250	Shared Neighborhood Hits	12
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

SO4A1_HUMAN
NC score	0.005789 (rank : 253)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	217	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

CCD27_MOUSE
NC score	0.005779 (rank : 254)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	217	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

VATB1_HUMAN
NC score	0.005625 (rank : 255)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	217	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P15313	Gene names	ATP6V1B1, ATP6B1, VATB, VPP3
Domain Architecture
Description	Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) (V- ATPase B1 subunit) (Vacuolar proton pump B isoform 1) (Endomembrane proton pump 58 kDa subunit).

STAC3_HUMAN
NC score	0.005532 (rank : 256)	θ value	6.88961 (rank : 199)
Query Neighborhood Hits	217	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

P85A_HUMAN
NC score	0.005386 (rank : 257)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	217	Target Neighborhood Hits	479	Shared Neighborhood Hits	14
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CTRO_MOUSE
NC score	0.005379 (rank : 258)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	217	Target Neighborhood Hits	2344	Shared Neighborhood Hits	70
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ST2B1_HUMAN
NC score	0.004802 (rank : 259)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	217	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

NID2_HUMAN
NC score	0.004555 (rank : 260)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	217	Target Neighborhood Hits	456	Shared Neighborhood Hits	10
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

ANK3_HUMAN
NC score	0.004530 (rank : 261)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	217	Target Neighborhood Hits	853	Shared Neighborhood Hits	45
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CP4F8_HUMAN
NC score	0.004308 (rank : 262)	θ value	0.813845 (rank : 128)
Query Neighborhood Hits	217	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P98187	Gene names	CYP4F8
Domain Architecture
Description	Cytochrome P450 4F8 (EC 1.14.14.1) (CYPIVF8).

HDAC7_MOUSE
NC score	0.004291 (rank : 263)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	217	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2B3, Q8C2C9, Q8C8X4, Q8CB80, Q8CDA3, Q9JL72	Gene names	Hdac7a, Hdac7
Domain Architecture
Description	Histone deacetylase 7a (HD7a).

USP9Y_HUMAN
NC score	0.003628 (rank : 264)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	217	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

ZN592_HUMAN
NC score	0.002717 (rank : 265)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	217	Target Neighborhood Hits	762	Shared Neighborhood Hits	15
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

STK10_HUMAN
NC score	0.002700 (rank : 266)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	217	Target Neighborhood Hits	1921	Shared Neighborhood Hits	65
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ARHGG_MOUSE
NC score	0.002518 (rank : 267)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	217	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

MRCKA_HUMAN
NC score	-0.002099 (rank : 268)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	217	Target Neighborhood Hits	1999	Shared Neighborhood Hits	42
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

M3K1_MOUSE
NC score	-0.003704 (rank : 269)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	217	Target Neighborhood Hits	952	Shared Neighborhood Hits	13
SwissProt Accessions	P53349, Q60831, Q9R0U3, Q9R256	Gene names	Map3k1, Mekk, Mekk1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1).

HKR3_HUMAN
NC score	-0.005696 (rank : 270)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	217	Target Neighborhood Hits	839	Shared Neighborhood Hits	12
SwissProt Accessions	P10074	Gene names	HKR3
Domain Architecture
Description	Krueppel-related zinc finger protein 3 (Protein HKR3).

ZFP95_HUMAN
NC score	-0.005817 (rank : 271)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	217	Target Neighborhood Hits	775	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).