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Network neighborhood for query Sequence : VATB1_HUMAN

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VATB1_HUMAN
SwissProt Accessions	P15313	Gene names	ATP6V1B1, ATP6B1, VATB, VPP3
Domain Architecture
Description	Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) (V- ATPase B1 subunit) (Vacuolar proton pump B isoform 1) (Endomembrane proton pump 58 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

VATB1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P15313	Gene names	ATP6V1B1, ATP6B1, VATB, VPP3
Domain Architecture
Description	Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) (V- ATPase B1 subunit) (Vacuolar proton pump B isoform 1) (Endomembrane proton pump 58 kDa subunit).

VATB2_HUMAN
θ value	0 (rank : 2)	NC score	0.998674 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21281, Q14544, Q15859, Q96IR0	Gene names	ATP6V1B2, ATP6B2
Domain Architecture
Description	Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit) (HO57).

VATB2_MOUSE
θ value	0 (rank : 3)	NC score	0.998658 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P62814, O09045, P50517	Gene names	Atp6v1b2, Atp6b2, Vat2
Domain Architecture	No domain graphic available
Description	Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit).

ATPB_HUMAN
θ value	3.87602e-27 (rank : 4)	NC score	0.758643 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P06576, Q14283	Gene names	ATP5B, ATPMB, ATPSB
Domain Architecture
Description	ATP synthase subunit beta, mitochondrial precursor (EC 3.6.3.14).

ATPB_MOUSE
θ value	5.06226e-27 (rank : 5)	NC score	0.762548 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P56480, Q3UF69, Q9CWX7	Gene names	Atp5b
Domain Architecture
Description	ATP synthase subunit beta, mitochondrial precursor (EC 3.6.3.14).

ATPA_HUMAN
θ value	2.43343e-21 (rank : 6)	NC score	0.706002 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P25705, Q8IXV2, Q96FB4, Q96HW2, Q96IR6, Q9BTV8	Gene names	ATP5A1, ATP5A
Domain Architecture
Description	ATP synthase subunit alpha, mitochondrial precursor (EC 3.6.3.14).

ATPA_MOUSE
θ value	2.43343e-21 (rank : 7)	NC score	0.706610 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q03265, Q3TFN0, Q3THN8, Q3TPR0, Q3TPV3, Q3TZU3, Q3UIR7, Q543Y6	Gene names	Atp5a1
Domain Architecture
Description	ATP synthase subunit alpha, mitochondrial precursor (EC 3.6.3.14).

VATA1_MOUSE
θ value	8.95645e-16 (rank : 8)	NC score	0.606789 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

VATA1_HUMAN
θ value	1.16975e-15 (rank : 9)	NC score	0.607196 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

VATA2_HUMAN
θ value	3.40345e-15 (rank : 10)	NC score	0.605525 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P38607	Gene names	ATP6V1A2, ATP6A2, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, osteoclast isoform (EC 3.6.3.14) (V-ATPase subunit A 2) (Vacuolar proton pump alpha subunit 2) (V-ATPase 69 kDa subunit 2) (Isoform HO68).

TAF4_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.026045 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	687	Shared Neighborhood Hits	3
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PK3CA_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.008563 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

BPTF_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.005692 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	786	Shared Neighborhood Hits	4
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRPF3_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.005625 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

Hits sorted by NC score

VATB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P15313	Gene names	ATP6V1B1, ATP6B1, VATB, VPP3
Domain Architecture
Description	Vacuolar ATP synthase subunit B, kidney isoform (EC 3.6.3.14) (V- ATPase B1 subunit) (Vacuolar proton pump B isoform 1) (Endomembrane proton pump 58 kDa subunit).

VATB2_HUMAN
NC score	0.998674 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21281, Q14544, Q15859, Q96IR0	Gene names	ATP6V1B2, ATP6B2
Domain Architecture
Description	Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit) (HO57).

VATB2_MOUSE
NC score	0.998658 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P62814, O09045, P50517	Gene names	Atp6v1b2, Atp6b2, Vat2
Domain Architecture	No domain graphic available
Description	Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit).

ATPB_MOUSE
NC score	0.762548 (rank : 4)	θ value	5.06226e-27 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P56480, Q3UF69, Q9CWX7	Gene names	Atp5b
Domain Architecture
Description	ATP synthase subunit beta, mitochondrial precursor (EC 3.6.3.14).

ATPB_HUMAN
NC score	0.758643 (rank : 5)	θ value	3.87602e-27 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	P06576, Q14283	Gene names	ATP5B, ATPMB, ATPSB
Domain Architecture
Description	ATP synthase subunit beta, mitochondrial precursor (EC 3.6.3.14).

ATPA_MOUSE
NC score	0.706610 (rank : 6)	θ value	2.43343e-21 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q03265, Q3TFN0, Q3THN8, Q3TPR0, Q3TPV3, Q3TZU3, Q3UIR7, Q543Y6	Gene names	Atp5a1
Domain Architecture
Description	ATP synthase subunit alpha, mitochondrial precursor (EC 3.6.3.14).

ATPA_HUMAN
NC score	0.706002 (rank : 7)	θ value	2.43343e-21 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	P25705, Q8IXV2, Q96FB4, Q96HW2, Q96IR6, Q9BTV8	Gene names	ATP5A1, ATP5A
Domain Architecture
Description	ATP synthase subunit alpha, mitochondrial precursor (EC 3.6.3.14).

VATA1_HUMAN
NC score	0.607196 (rank : 8)	θ value	1.16975e-15 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

VATA1_MOUSE
NC score	0.606789 (rank : 9)	θ value	8.95645e-16 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

VATA2_HUMAN
NC score	0.605525 (rank : 10)	θ value	3.40345e-15 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	P38607	Gene names	ATP6V1A2, ATP6A2, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, osteoclast isoform (EC 3.6.3.14) (V-ATPase subunit A 2) (Vacuolar proton pump alpha subunit 2) (V-ATPase 69 kDa subunit 2) (Isoform HO68).

TAF4_HUMAN
NC score	0.026045 (rank : 11)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	687	Shared Neighborhood Hits	3
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

PK3CA_HUMAN
NC score	0.008563 (rank : 12)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

BPTF_HUMAN
NC score	0.005692 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	786	Shared Neighborhood Hits	4
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRPF3_HUMAN
NC score	0.005625 (rank : 14)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.