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Network neighborhood for query Sequence : BRD7_MOUSE

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BRD7_MOUSE
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BRD7_HUMAN
θ value	0 (rank : 1)	NC score	0.982216 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD9_MOUSE
θ value	5.8972e-76 (rank : 3)	NC score	0.911941 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD9_HUMAN
θ value	3.70236e-70 (rank : 4)	NC score	0.914325 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRPF1_HUMAN
θ value	3.63628e-17 (rank : 5)	NC score	0.465122 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	259	Shared Neighborhood Hits	54
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
θ value	8.10077e-17 (rank : 6)	NC score	0.490237 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	5.25075e-16 (rank : 7)	NC score	0.490125 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRD2_HUMAN
θ value	1.47974e-10 (rank : 8)	NC score	0.556355 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	242	Shared Neighborhood Hits	53
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

SMCA2_HUMAN
θ value	8.11959e-09 (rank : 9)	NC score	0.222019 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	503	Shared Neighborhood Hits	68
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

BRD8_HUMAN
θ value	1.06045e-08 (rank : 10)	NC score	0.551757 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	1.06045e-08 (rank : 11)	NC score	0.524744 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

PCAF_HUMAN
θ value	1.06045e-08 (rank : 12)	NC score	0.542487 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

CBP_MOUSE
θ value	1.38499e-08 (rank : 13)	NC score	0.418749 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	1051	Shared Neighborhood Hits	63
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PB1_HUMAN
θ value	1.80886e-08 (rank : 14)	NC score	0.518292 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TAF1_HUMAN
θ value	1.80886e-08 (rank : 15)	NC score	0.527994 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BRD3_HUMAN
θ value	2.36244e-08 (rank : 16)	NC score	0.528833 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	2.36244e-08 (rank : 17)	NC score	0.527723 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

EP300_HUMAN
θ value	2.36244e-08 (rank : 18)	NC score	0.436653 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
θ value	5.26297e-08 (rank : 19)	NC score	0.431113 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	1.53129e-07 (rank : 20)	NC score	0.492523 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

TAF1L_HUMAN
θ value	1.53129e-07 (rank : 21)	NC score	0.512158 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

BRD4_HUMAN
θ value	3.41135e-07 (rank : 22)	NC score	0.482314 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	851	Shared Neighborhood Hits	75
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	3.41135e-07 (rank : 23)	NC score	0.476602 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	845	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SMCA4_HUMAN
θ value	3.41135e-07 (rank : 24)	NC score	0.221688 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	67
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ATAD2_MOUSE
θ value	1.29631e-06 (rank : 25)	NC score	0.264503 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BPTF_HUMAN
θ value	1.29631e-06 (rank : 26)	NC score	0.424764 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	786	Shared Neighborhood Hits	77
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRWD1_HUMAN
θ value	1.29631e-06 (rank : 27)	NC score	0.280987 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	448	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BAZ1B_MOUSE
θ value	3.77169e-06 (rank : 28)	NC score	0.423025 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRDT_HUMAN
θ value	3.77169e-06 (rank : 29)	NC score	0.504666 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BAZ2A_HUMAN
θ value	4.92598e-06 (rank : 30)	NC score	0.420535 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	780	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2B_HUMAN
θ value	4.92598e-06 (rank : 31)	NC score	0.417920 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	803	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_MOUSE
θ value	6.43352e-06 (rank : 32)	NC score	0.413117 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	744	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

ATAD2_HUMAN
θ value	1.43324e-05 (rank : 33)	NC score	0.260224 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	322	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

BAZ1A_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.419350 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	2.44474e-05 (rank : 35)	NC score	0.401142 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	701	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BRWD1_MOUSE
θ value	3.19293e-05 (rank : 36)	NC score	0.271817 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	478	Shared Neighborhood Hits	53
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BRDT_MOUSE
θ value	5.44631e-05 (rank : 37)	NC score	0.503735 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	243	Shared Neighborhood Hits	57
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

TIF1A_HUMAN
θ value	5.44631e-05 (rank : 38)	NC score	0.349316 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	55
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	5.44631e-05 (rank : 39)	NC score	0.351870 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

GCNL2_HUMAN
θ value	0.000158464 (rank : 40)	NC score	0.477910 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	0.000270298 (rank : 41)	NC score	0.471282 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

TRI66_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.300315 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	479	Shared Neighborhood Hits	54
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

GOGA6_HUMAN
θ value	0.0193708 (rank : 43)	NC score	0.038128 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	1007	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

RPA1_MOUSE
θ value	0.0193708 (rank : 44)	NC score	0.053727 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

TRI66_MOUSE
θ value	0.0193708 (rank : 45)	NC score	0.293869 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SFRS4_MOUSE
θ value	0.0563607 (rank : 46)	NC score	0.030679 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

T2FA_HUMAN
θ value	0.0736092 (rank : 47)	NC score	0.072997 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

MYO6_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.024417 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	727	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TRHY_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.028567 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	1385	Shared Neighborhood Hits	46
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CCD55_MOUSE
θ value	0.163984 (rank : 50)	NC score	0.067786 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	43
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TNNT3_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.045146 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

TTF1_MOUSE
θ value	0.163984 (rank : 52)	NC score	0.076051 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

CLSPN_MOUSE
θ value	0.21417 (rank : 53)	NC score	0.050567 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

TIF1G_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.275187 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	410	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

AZI1_MOUSE
θ value	0.279714 (rank : 55)	NC score	0.039291 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	990	Shared Neighborhood Hits	57
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

TIF1G_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.268965 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	498	Shared Neighborhood Hits	53
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

CD2L1_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.010297 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	1467	Shared Neighborhood Hits	42
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

PKCB1_HUMAN
θ value	0.365318 (rank : 58)	NC score	0.299338 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	488	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SAKS1_MOUSE
θ value	0.365318 (rank : 59)	NC score	0.054724 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

SFR12_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.042383 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	553	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ZC313_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.063037 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZMY11_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.202184 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	0.47712 (rank : 63)	NC score	0.203191 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

AKAP9_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.038164 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	1710	Shared Neighborhood Hits	70
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

RBM25_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.041322 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	42
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

WDR63_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.056608 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWG1, Q96L72, Q96NU4	Gene names	WDR63
Domain Architecture	No domain graphic available
Description	WD repeat protein 63 (Testis development protein NYD-SP29).

CD2L1_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.009679 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	1463	Shared Neighborhood Hits	45
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CF188_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.042485 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R100, Q8C3G8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188 homolog.

PCDG2_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.007889 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5H1, Q9Y5D5	Gene names	PCDHGA2
Domain Architecture
Description	Protocadherin gamma A2 precursor (PCDH-gamma-A2).

PRP40_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.057031 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SAKS1_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.057380 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

ATRX_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.064294 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	75
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

INCE_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.035699 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	903	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MYST3_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.078092 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RBM15_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.027962 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	309	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RPTN_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.052657 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SYNE2_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.028335 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	1323	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CCHCR_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.026798 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	717	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

E41L1_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.019056 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

GRAP1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.026929 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	944	Shared Neighborhood Hits	39
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

LMNA_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.016787 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	661	Shared Neighborhood Hits	37
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

CN118_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.029248 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWQ4, Q6PEJ7, Q9NWH0, Q9ULR8	Gene names	C14orf118, KIAA1152
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf118.

CN145_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.042272 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	1196	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

INCE_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.032406 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	978	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MY18A_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.044092 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	1989	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYO6_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.020566 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	586	Shared Neighborhood Hits	29
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

RXRA_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.014304 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

GRAP1_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.041376 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	1234	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HTSF1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.028192 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

LMNA_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.016159 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	653	Shared Neighborhood Hits	35
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

PRP40_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.054423 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RIF1_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.029027 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	315	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

RPA1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.040043 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

BRCA2_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.020171 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

CROP_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.026535 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

DHX16_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.015092 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

E41L2_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.012037 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	19
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MD1L1_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.029531 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	1001	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MFAP1_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.037167 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

PTPRG_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.005307 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

MFAP1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.032066 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

RXRA_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.013847 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SEPT4_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.009571 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

SRRM2_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.028868 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	1296	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TTF2_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.046427 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	364	Shared Neighborhood Hits	37
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

CCD94_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.021825 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

CI093_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.037774 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	1088	Shared Neighborhood Hits	64
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CNGA1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.006408 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

DDX46_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.005605 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

K0133_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.019092 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

KIF4A_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.028691 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	1159	Shared Neighborhood Hits	72
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NEST_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.038001 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	1305	Shared Neighborhood Hits	69
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

SFR12_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.032476 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

TRML2_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.017206 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q2LA85	Gene names	Treml2, Tlt2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

UACA_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.025544 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UBP8_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.008575 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

ANR12_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.027203 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	1081	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CJ012_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.040230 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	467	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CM003_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.025568 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C263	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf3 homolog.

CN118_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.021912 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE65, Q6ZPW9, Q8CD08, Q9DA49	Gene names	Kiaa1152
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf118 homolog.

ITSN1_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.027779 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	1669	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYO5B_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.024484 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	911	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.024556 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	1206	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

ROCK2_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.011240 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	2073	Shared Neighborhood Hits	70
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SFR17_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.020946 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	325	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

STK10_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.016708 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	1921	Shared Neighborhood Hits	79
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TAOK3_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.007599 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	1458	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

TITIN_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.003940 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	2923	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TNNT2_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.024276 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	395	Shared Neighborhood Hits	26
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

ZC3H6_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.014546 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ABTAP_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.017046 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ABTAP_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.025431 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	381	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

CASP2_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.005715 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

CD2L2_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.008811 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	1439	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

DMD_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.020785 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EEA1_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.024892 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	1637	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

IF2P_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.027569 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	889	Shared Neighborhood Hits	44
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MY18A_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.042203 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	1929	Shared Neighborhood Hits	90
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SFR11_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.035897 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SRPK2_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.008029 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	765	Shared Neighborhood Hits	22
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

SRRM2_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.046834 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ACINU_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.051811 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AF10_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.092088 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.094375 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.103302 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AIRE_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.110364 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.109067 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ATRX_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.054816 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	58
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCD55_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.053700 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CHD3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.082030 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	397	Shared Neighborhood Hits	29
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.078513 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	365	Shared Neighborhood Hits	27
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.079778 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.080230 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	349	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

DPF1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.062488 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	20
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.067596 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

IWS1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.056362 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	1241	Shared Neighborhood Hits	75
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.055764 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	1258	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JAD1A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.055548 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1D_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.052085 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JADE1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.105021 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.105095 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.101501 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	199	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.101653 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.104713 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.108674 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JHD3A_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.053029 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.053697 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.055566 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.054528 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3C_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.052138 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3C_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.054011 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

LEO1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.052786 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	958	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.052435 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	946	Shared Neighborhood Hits	62
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.120871 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MDC1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.052237 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	1446	Shared Neighborhood Hits	64
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MLL2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.059956 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	1788	Shared Neighborhood Hits	54
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.067871 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	1644	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.066101 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MTF2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.050197 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MYST3_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.070974 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.072758 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	671	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.066945 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NASP_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.051964 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NIPBL_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.078161 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	1311	Shared Neighborhood Hits	84
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOP14_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.055444 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	573	Shared Neighborhood Hits	68
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NPBL_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.050511 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	1041	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.059395 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.062726 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	472	Shared Neighborhood Hits	36
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.098258 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.102032 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	285	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.070325 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.067956 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.083573 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.082258 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF12_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.085818 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.085561 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF14_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.100579 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	40
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.100177 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.056386 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.056124 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF20_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.066347 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.054605 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

REQU_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.073008 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	523	Shared Neighborhood Hits	23
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.070874 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.105371 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.056875 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TCAL5_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.050666 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	806	Shared Neighborhood Hits	57
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TIF1B_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.096326 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.094156 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.059157 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UHRF1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.053921 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	20
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.056328 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.050281 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.054133 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

YTDC1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.054941 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

Hits sorted by NC score

BRD7_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD7_HUMAN
NC score	0.982216 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD9_HUMAN
NC score	0.914325 (rank : 3)	θ value	3.70236e-70 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
NC score	0.911941 (rank : 4)	θ value	5.8972e-76 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRD2_HUMAN
NC score	0.556355 (rank : 5)	θ value	1.47974e-10 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	242	Shared Neighborhood Hits	53
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD8_HUMAN
NC score	0.551757 (rank : 6)	θ value	1.06045e-08 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

PCAF_HUMAN
NC score	0.542487 (rank : 7)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	46
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRD3_HUMAN
NC score	0.528833 (rank : 8)	θ value	2.36244e-08 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

TAF1_HUMAN
NC score	0.527994 (rank : 9)	θ value	1.80886e-08 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

BRD3_MOUSE
NC score	0.527723 (rank : 10)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	402	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD8_MOUSE
NC score	0.524744 (rank : 11)	θ value	1.06045e-08 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

PB1_HUMAN
NC score	0.518292 (rank : 12)	θ value	1.80886e-08 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	261	Shared Neighborhood Hits	48
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TAF1L_HUMAN
NC score	0.512158 (rank : 13)	θ value	1.53129e-07 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

BRDT_HUMAN
NC score	0.504666 (rank : 14)	θ value	3.77169e-06 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	58
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
NC score	0.503735 (rank : 15)	θ value	5.44631e-05 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	243	Shared Neighborhood Hits	57
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CECR2_HUMAN
NC score	0.492523 (rank : 16)	θ value	1.53129e-07 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	543	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BRD1_HUMAN
NC score	0.490237 (rank : 17)	θ value	8.10077e-17 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
NC score	0.490125 (rank : 18)	θ value	5.25075e-16 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRD4_HUMAN
NC score	0.482314 (rank : 19)	θ value	3.41135e-07 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	851	Shared Neighborhood Hits	75
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

GCNL2_HUMAN
NC score	0.477910 (rank : 20)	θ value	0.000158464 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	159	Shared Neighborhood Hits	46
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

BRD4_MOUSE
NC score	0.476602 (rank : 21)	θ value	3.41135e-07 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	845	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

GCNL2_MOUSE
NC score	0.471282 (rank : 22)	θ value	0.000270298 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

BRPF1_HUMAN
NC score	0.465122 (rank : 23)	θ value	3.63628e-17 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	259	Shared Neighborhood Hits	54
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

EP300_HUMAN
NC score	0.436653 (rank : 24)	θ value	2.36244e-08 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
NC score	0.431113 (rank : 25)	θ value	5.26297e-08 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BPTF_HUMAN
NC score	0.424764 (rank : 26)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	786	Shared Neighborhood Hits	77
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BAZ1B_MOUSE
NC score	0.423025 (rank : 27)	θ value	3.77169e-06 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
NC score	0.420535 (rank : 28)	θ value	4.92598e-06 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	780	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ1A_HUMAN
NC score	0.419350 (rank : 29)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CBP_MOUSE
NC score	0.418749 (rank : 30)	θ value	1.38499e-08 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	1051	Shared Neighborhood Hits	63
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BAZ2B_HUMAN
NC score	0.417920 (rank : 31)	θ value	4.92598e-06 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	803	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BAZ2A_MOUSE
NC score	0.413117 (rank : 32)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	744	Shared Neighborhood Hits	65
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ1B_HUMAN
NC score	0.401142 (rank : 33)	θ value	2.44474e-05 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	701	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

TIF1A_MOUSE
NC score	0.351870 (rank : 34)	θ value	5.44631e-05 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	307	Shared Neighborhood Hits	54
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.349316 (rank : 35)	θ value	5.44631e-05 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	55
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI66_HUMAN
NC score	0.300315 (rank : 36)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	479	Shared Neighborhood Hits	54
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PKCB1_HUMAN
NC score	0.299338 (rank : 37)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	488	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRI66_MOUSE
NC score	0.293869 (rank : 38)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	55
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BRWD1_HUMAN
NC score	0.280987 (rank : 39)	θ value	1.29631e-06 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	448	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TIF1G_HUMAN
NC score	0.275187 (rank : 40)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	410	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

BRWD1_MOUSE
NC score	0.271817 (rank : 41)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	478	Shared Neighborhood Hits	53
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

TIF1G_MOUSE
NC score	0.268965 (rank : 42)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	498	Shared Neighborhood Hits	53
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ATAD2_MOUSE
NC score	0.264503 (rank : 43)	θ value	1.29631e-06 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.260224 (rank : 44)	θ value	1.43324e-05 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	322	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SMCA2_HUMAN
NC score	0.222019 (rank : 45)	θ value	8.11959e-09 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	503	Shared Neighborhood Hits	68
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.221688 (rank : 46)	θ value	3.41135e-07 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	67
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

ZMY11_MOUSE
NC score	0.203191 (rank : 47)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.202184 (rank : 48)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	42
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

LY10_HUMAN
NC score	0.120871 (rank : 49)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

AIRE_HUMAN
NC score	0.110364 (rank : 50)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	144	Shared Neighborhood Hits	21
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.109067 (rank : 51)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	196	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

JADE3_MOUSE
NC score	0.108674 (rank : 52)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	22
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

RSF1_HUMAN
NC score	0.105371 (rank : 53)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	539	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

JADE1_MOUSE
NC score	0.105095 (rank : 54)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_HUMAN
NC score	0.105021 (rank : 55)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
NC score	0.104713 (rank : 56)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	19
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

AF17_HUMAN
NC score	0.103302 (rank : 57)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

PF21A_MOUSE
NC score	0.102032 (rank : 58)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	285	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

JADE2_MOUSE
NC score	0.101653 (rank : 59)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_HUMAN
NC score	0.101501 (rank : 60)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	199	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

PHF14_HUMAN
NC score	0.100579 (rank : 61)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	40
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
NC score	0.100177 (rank : 62)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	342	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PF21A_HUMAN
NC score	0.098258 (rank : 63)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	27
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TIF1B_HUMAN
NC score	0.096326 (rank : 64)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

AF10_MOUSE
NC score	0.094375 (rank : 65)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

TIF1B_MOUSE
NC score	0.094156 (rank : 66)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

AF10_HUMAN
NC score	0.092088 (rank : 67)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

PHF12_HUMAN
NC score	0.085818 (rank : 68)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.085561 (rank : 69)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	23
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF10_HUMAN
NC score	0.083573 (rank : 70)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.082258 (rank : 71)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	131	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

CHD3_HUMAN
NC score	0.082030 (rank : 72)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	397	Shared Neighborhood Hits	29
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
NC score	0.080230 (rank : 73)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	349	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.079778 (rank : 74)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.078513 (rank : 75)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	365	Shared Neighborhood Hits	27
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

NIPBL_HUMAN
NC score	0.078161 (rank : 76)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	1311	Shared Neighborhood Hits	84
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MYST3_HUMAN
NC score	0.078092 (rank : 77)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	45
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

TTF1_MOUSE
NC score	0.076051 (rank : 78)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

REQU_HUMAN
NC score	0.073008 (rank : 79)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	523	Shared Neighborhood Hits	23
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

T2FA_HUMAN
NC score	0.072997 (rank : 80)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

MYST4_HUMAN
NC score	0.072758 (rank : 81)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	671	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST3_MOUSE
NC score	0.070974 (rank : 82)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	688	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

REQU_MOUSE
NC score	0.070874 (rank : 83)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	23
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PF21B_HUMAN
NC score	0.070325 (rank : 84)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	26
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
NC score	0.067956 (rank : 85)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MLL3_HUMAN
NC score	0.067871 (rank : 86)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	1644	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CCD55_MOUSE
NC score	0.067786 (rank : 87)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	519	Shared Neighborhood Hits	43
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

DPF1_MOUSE
NC score	0.067596 (rank : 88)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST4_MOUSE
NC score	0.066945 (rank : 89)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PHF20_HUMAN
NC score	0.066347 (rank : 90)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

MLL3_MOUSE
NC score	0.066101 (rank : 91)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ATRX_HUMAN
NC score	0.064294 (rank : 92)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	75
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ZC313_HUMAN
NC score	0.063037 (rank : 93)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	772	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

NSD1_MOUSE
NC score	0.062726 (rank : 94)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	472	Shared Neighborhood Hits	36
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

DPF1_HUMAN
NC score	0.062488 (rank : 95)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	20
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL2_HUMAN
NC score	0.059956 (rank : 96)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	1788	Shared Neighborhood Hits	54
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NSD1_HUMAN
NC score	0.059395 (rank : 97)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	427	Shared Neighborhood Hits	29
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TXND2_MOUSE
NC score	0.059157 (rank : 98)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

SAKS1_HUMAN
NC score	0.057380 (rank : 99)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	202	Shared Neighborhood Hits	23
SwissProt Accessions	Q04323, Q9BV93, Q9BVV5	Gene names	SAKS1
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein).

PRP40_MOUSE
NC score	0.057031 (rank : 100)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	447	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

SP110_HUMAN
NC score	0.056875 (rank : 101)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

WDR63_HUMAN
NC score	0.056608 (rank : 102)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWG1, Q96L72, Q96NU4	Gene names	WDR63
Domain Architecture	No domain graphic available
Description	WD repeat protein 63 (Testis development protein NYD-SP29).

PHF1_HUMAN
NC score	0.056386 (rank : 103)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

IWS1_HUMAN
NC score	0.056362 (rank : 104)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	1241	Shared Neighborhood Hits	75
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UHRF1_MOUSE
NC score	0.056328 (rank : 105)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	278	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PHF1_MOUSE
NC score	0.056124 (rank : 106)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

IWS1_MOUSE
NC score	0.055764 (rank : 107)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	1258	Shared Neighborhood Hits	74
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD3B_HUMAN
NC score	0.055566 (rank : 108)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JAD1A_HUMAN
NC score	0.055548 (rank : 109)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	328	Shared Neighborhood Hits	30
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

NOP14_HUMAN
NC score	0.055444 (rank : 110)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	573	Shared Neighborhood Hits	68
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

YTDC1_HUMAN
NC score	0.054941 (rank : 111)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	458	Shared Neighborhood Hits	46
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ATRX_MOUSE
NC score	0.054816 (rank : 112)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	58
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SAKS1_MOUSE
NC score	0.054724 (rank : 113)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	208	Shared Neighborhood Hits	22
SwissProt Accessions	Q922Y1, Q3UCP8	Gene names	Saks1, D19Ertd721e
Domain Architecture
Description	SAPK substrate protein 1 (UBA/UBX 33.3 kDa protein) (mY33K) (Protein 2B28).

PHF20_MOUSE
NC score	0.054605 (rank : 114)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

JHD3B_MOUSE
NC score	0.054528 (rank : 115)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PRP40_HUMAN
NC score	0.054423 (rank : 116)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

UHRF2_MOUSE
NC score	0.054133 (rank : 117)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

JHD3C_MOUSE
NC score	0.054011 (rank : 118)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

UHRF1_HUMAN
NC score	0.053921 (rank : 119)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	20
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RPA1_MOUSE
NC score	0.053727 (rank : 120)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

CCD55_HUMAN
NC score	0.053700 (rank : 121)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	513	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

JHD3A_MOUSE
NC score	0.053697 (rank : 122)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_HUMAN
NC score	0.053029 (rank : 123)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

LEO1_HUMAN
NC score	0.052786 (rank : 124)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	958	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

RPTN_HUMAN
NC score	0.052657 (rank : 125)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

LEO1_MOUSE
NC score	0.052435 (rank : 126)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	946	Shared Neighborhood Hits	62
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MDC1_HUMAN
NC score	0.052237 (rank : 127)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	1446	Shared Neighborhood Hits	64
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

JHD3C_HUMAN
NC score	0.052138 (rank : 128)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JAD1D_HUMAN
NC score	0.052085 (rank : 129)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

NASP_HUMAN
NC score	0.051964 (rank : 130)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	709	Shared Neighborhood Hits	59
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ACINU_HUMAN
NC score	0.051811 (rank : 131)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	828	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

TCAL5_HUMAN
NC score	0.050666 (rank : 132)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	806	Shared Neighborhood Hits	57
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CLSPN_MOUSE
NC score	0.050567 (rank : 133)	θ value	0.21417 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

NPBL_MOUSE
NC score	0.050511 (rank : 134)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	1041	Shared Neighborhood Hits	67
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

UHRF2_HUMAN
NC score	0.050281 (rank : 135)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	269	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

MTF2_HUMAN
NC score	0.050197 (rank : 136)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

SRRM2_MOUSE
NC score	0.046834 (rank : 137)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TTF2_MOUSE
NC score	0.046427 (rank : 138)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	364	Shared Neighborhood Hits	37
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TNNT3_HUMAN
NC score	0.045146 (rank : 139)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	327	Shared Neighborhood Hits	24
SwissProt Accessions	P45378, Q12975, Q12976, Q12977, Q12978, Q86TH6	Gene names	TNNT3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT) (Beta TnTF).

MY18A_MOUSE
NC score	0.044092 (rank : 140)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	1989	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CF188_MOUSE
NC score	0.042485 (rank : 141)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R100, Q8C3G8	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188 homolog.

SFR12_HUMAN
NC score	0.042383 (rank : 142)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	553	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

CN145_HUMAN
NC score	0.042272 (rank : 143)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	1196	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MY18A_HUMAN
NC score	0.042203 (rank : 144)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	1929	Shared Neighborhood Hits	90
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GRAP1_MOUSE
NC score	0.041376 (rank : 145)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	1234	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

RBM25_HUMAN
NC score	0.041322 (rank : 146)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	682	Shared Neighborhood Hits	42
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

CJ012_HUMAN
NC score	0.040230 (rank : 147)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	467	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

RPA1_HUMAN
NC score	0.040043 (rank : 148)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

AZI1_MOUSE
NC score	0.039291 (rank : 149)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	990	Shared Neighborhood Hits	57
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

AKAP9_HUMAN
NC score	0.038164 (rank : 150)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	1710	Shared Neighborhood Hits	70
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGA6_HUMAN
NC score	0.038128 (rank : 151)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	1007	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

NEST_HUMAN
NC score	0.038001 (rank : 152)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	1305	Shared Neighborhood Hits	69
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CI093_HUMAN
NC score	0.037774 (rank : 153)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	1088	Shared Neighborhood Hits	64
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MFAP1_HUMAN
NC score	0.037167 (rank : 154)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	28
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

SFR11_HUMAN
NC score	0.035897 (rank : 155)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

INCE_MOUSE
NC score	0.035699 (rank : 156)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	903	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

SFR12_MOUSE
NC score	0.032476 (rank : 157)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

INCE_HUMAN
NC score	0.032406 (rank : 158)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	978	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MFAP1_MOUSE
NC score	0.032066 (rank : 159)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	353	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

SFRS4_MOUSE
NC score	0.030679 (rank : 160)	θ value	0.0563607 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

MD1L1_MOUSE
NC score	0.029531 (rank : 161)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	1001	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CN118_HUMAN
NC score	0.029248 (rank : 162)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWQ4, Q6PEJ7, Q9NWH0, Q9ULR8	Gene names	C14orf118, KIAA1152
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf118.

RIF1_MOUSE
NC score	0.029027 (rank : 163)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	315	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SRRM2_HUMAN
NC score	0.028868 (rank : 164)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	1296	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

KIF4A_HUMAN
NC score	0.028691 (rank : 165)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	1159	Shared Neighborhood Hits	72
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

TRHY_HUMAN
NC score	0.028567 (rank : 166)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	1385	Shared Neighborhood Hits	46
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SYNE2_HUMAN
NC score	0.028335 (rank : 167)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	1323	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

HTSF1_HUMAN
NC score	0.028192 (rank : 168)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	408	Shared Neighborhood Hits	25
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

RBM15_HUMAN
NC score	0.027962 (rank : 169)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	309	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

ITSN1_MOUSE
NC score	0.027779 (rank : 170)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	1669	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IF2P_HUMAN
NC score	0.027569 (rank : 171)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	889	Shared Neighborhood Hits	44
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ANR12_HUMAN
NC score	0.027203 (rank : 172)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	1081	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GRAP1_HUMAN
NC score	0.026929 (rank : 173)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	944	Shared Neighborhood Hits	39
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

CCHCR_HUMAN
NC score	0.026798 (rank : 174)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	717	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CROP_MOUSE
NC score	0.026535 (rank : 175)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	403	Shared Neighborhood Hits	30
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CM003_MOUSE
NC score	0.025568 (rank : 176)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C263	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf3 homolog.

UACA_MOUSE
NC score	0.025544 (rank : 177)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	1620	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ABTAP_MOUSE
NC score	0.025431 (rank : 178)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	381	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

EEA1_MOUSE
NC score	0.024892 (rank : 179)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	1637	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MYO5C_HUMAN
NC score	0.024556 (rank : 180)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	1206	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO5B_HUMAN
NC score	0.024484 (rank : 181)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	911	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO6_HUMAN
NC score	0.024417 (rank : 182)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	727	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TNNT2_MOUSE
NC score	0.024276 (rank : 183)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	395	Shared Neighborhood Hits	26
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

CN118_MOUSE
NC score	0.021912 (rank : 184)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PE65, Q6ZPW9, Q8CD08, Q9DA49	Gene names	Kiaa1152
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf118 homolog.

CCD94_MOUSE
NC score	0.021825 (rank : 185)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D6J3	Gene names	Ccdc94
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 94.

SFR17_HUMAN
NC score	0.020946 (rank : 186)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	325	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

DMD_HUMAN
NC score	0.020785 (rank : 187)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	1135	Shared Neighborhood Hits	56
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

MYO6_MOUSE
NC score	0.020566 (rank : 188)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	586	Shared Neighborhood Hits	29
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

BRCA2_MOUSE
NC score	0.020171 (rank : 189)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	222	Shared Neighborhood Hits	15
SwissProt Accessions	P97929, O35922, P97383	Gene names	Brca2, Fancd1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein homolog (Fanconi anemia group D1 protein homolog).

K0133_HUMAN
NC score	0.019092 (rank : 190)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

E41L1_HUMAN
NC score	0.019056 (rank : 191)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

TRML2_MOUSE
NC score	0.017206 (rank : 192)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q2LA85	Gene names	Treml2, Tlt2
Domain Architecture	No domain graphic available
Description	Trem-like transcript 2 protein precursor (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2).

ABTAP_HUMAN
NC score	0.017046 (rank : 193)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

LMNA_MOUSE
NC score	0.016787 (rank : 194)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	661	Shared Neighborhood Hits	37
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

STK10_HUMAN
NC score	0.016708 (rank : 195)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	1921	Shared Neighborhood Hits	79
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

LMNA_HUMAN
NC score	0.016159 (rank : 196)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	653	Shared Neighborhood Hits	35
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

DHX16_HUMAN
NC score	0.015092 (rank : 197)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

ZC3H6_HUMAN
NC score	0.014546 (rank : 198)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	228	Shared Neighborhood Hits	9
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

RXRA_MOUSE
NC score	0.014304 (rank : 199)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_HUMAN
NC score	0.013847 (rank : 200)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	223	Shared Neighborhood Hits	8
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

E41L2_HUMAN
NC score	0.012037 (rank : 201)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	19
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ROCK2_HUMAN
NC score	0.011240 (rank : 202)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	2073	Shared Neighborhood Hits	70
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CD2L1_HUMAN
NC score	0.010297 (rank : 203)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	1467	Shared Neighborhood Hits	42
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
NC score	0.009679 (rank : 204)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	1463	Shared Neighborhood Hits	45
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

SEPT4_MOUSE
NC score	0.009571 (rank : 205)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P28661, Q5ND15	Gene names	Sept4, Pnutl2
Domain Architecture
Description	Septin-4 (Peanut-like protein 2) (Brain protein H5).

CD2L2_HUMAN
NC score	0.008811 (rank : 206)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	1439	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

UBP8_MOUSE
NC score	0.008575 (rank : 207)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

SRPK2_MOUSE
NC score	0.008029 (rank : 208)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	765	Shared Neighborhood Hits	22
SwissProt Accessions	O54781, Q8VCD9	Gene names	Srpk2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK2 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific kinase 2) (SFRS protein kinase 2).

PCDG2_HUMAN
NC score	0.007889 (rank : 209)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5H1, Q9Y5D5	Gene names	PCDHGA2
Domain Architecture
Description	Protocadherin gamma A2 precursor (PCDH-gamma-A2).

TAOK3_MOUSE
NC score	0.007599 (rank : 210)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	1458	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BYC6, Q3V3B3	Gene names	Taok3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3).

CNGA1_HUMAN
NC score	0.006408 (rank : 211)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CASP2_MOUSE
NC score	0.005715 (rank : 212)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P29594, O08737, Q3TCM0, Q8C9H7, Q8K241	Gene names	Casp2, Ich1, Nedd-2, Nedd2
Domain Architecture
Description	Caspase-2 precursor (EC 3.4.22.-) (CASP-2) (ICH-1 protease) (NEDD2 protein) (Neural precursor cell expressed developmentally down- regulated protein 2) (NEDD-2) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].

DDX46_HUMAN
NC score	0.005605 (rank : 213)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	357	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

PTPRG_MOUSE
NC score	0.005307 (rank : 214)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

TITIN_HUMAN
NC score	0.003940 (rank : 215)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	2923	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).