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Network neighborhood for query Sequence : DDX46_HUMAN

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DDX46_HUMAN
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DDX46_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	357
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	0 (rank : 2)	NC score	0.996339 (rank : 2)
Query Neighborhood Hits	357	Target Neighborhood Hits	358	Shared Neighborhood Hits	309
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX5_MOUSE
θ value	1.59483e-97 (rank : 3)	NC score	0.964111 (rank : 6)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX17_HUMAN
θ value	2.08291e-97 (rank : 4)	NC score	0.965721 (rank : 4)
Query Neighborhood Hits	357	Target Neighborhood Hits	104	Shared Neighborhood Hits	88
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX17_MOUSE
θ value	2.08291e-97 (rank : 5)	NC score	0.965843 (rank : 3)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX5_HUMAN
θ value	4.64023e-97 (rank : 6)	NC score	0.964038 (rank : 7)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX43_HUMAN
θ value	9.69798e-87 (rank : 7)	NC score	0.964893 (rank : 5)
Query Neighborhood Hits	357	Target Neighborhood Hits	120	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX23_HUMAN
θ value	3.68522e-86 (rank : 8)	NC score	0.961919 (rank : 8)
Query Neighborhood Hits	357	Target Neighborhood Hits	486	Shared Neighborhood Hits	227
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX53_HUMAN
θ value	1.54831e-84 (rank : 9)	NC score	0.958601 (rank : 9)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX3Y_HUMAN
θ value	6.30065e-78 (rank : 10)	NC score	0.950983 (rank : 22)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

PL10_MOUSE
θ value	1.07473e-77 (rank : 11)	NC score	0.951982 (rank : 18)
Query Neighborhood Hits	357	Target Neighborhood Hits	120	Shared Neighborhood Hits	92
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_HUMAN
θ value	1.40363e-77 (rank : 12)	NC score	0.952283 (rank : 14)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	94
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3X_MOUSE
θ value	6.96618e-77 (rank : 13)	NC score	0.951832 (rank : 19)
Query Neighborhood Hits	357	Target Neighborhood Hits	117	Shared Neighborhood Hits	91
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX3Y_MOUSE
θ value	1.11217e-74 (rank : 14)	NC score	0.952275 (rank : 15)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX4_HUMAN
θ value	1.7756e-72 (rank : 15)	NC score	0.957252 (rank : 13)
Query Neighborhood Hits	357	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX4_MOUSE
θ value	1.15091e-71 (rank : 16)	NC score	0.958341 (rank : 10)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX41_HUMAN
θ value	3.83135e-67 (rank : 17)	NC score	0.957661 (rank : 11)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	5.00389e-67 (rank : 18)	NC score	0.957258 (rank : 12)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX47_HUMAN
θ value	2.65945e-60 (rank : 19)	NC score	0.952009 (rank : 17)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_MOUSE
θ value	2.25136e-59 (rank : 20)	NC score	0.952065 (rank : 16)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX54_MOUSE
θ value	6.55044e-59 (rank : 21)	NC score	0.945099 (rank : 27)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX49_HUMAN
θ value	1.78386e-56 (rank : 22)	NC score	0.947390 (rank : 24)
Query Neighborhood Hits	357	Target Neighborhood Hits	223	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX54_HUMAN
θ value	2.32979e-56 (rank : 23)	NC score	0.942543 (rank : 30)
Query Neighborhood Hits	357	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX49_MOUSE
θ value	5.19021e-56 (rank : 24)	NC score	0.949552 (rank : 23)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX52_HUMAN
θ value	5.73848e-55 (rank : 25)	NC score	0.951816 (rank : 20)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
θ value	1.08223e-53 (rank : 26)	NC score	0.951741 (rank : 21)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX6_HUMAN
θ value	1.19655e-52 (rank : 27)	NC score	0.945475 (rank : 25)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
θ value	1.19655e-52 (rank : 28)	NC score	0.945235 (rank : 26)
Query Neighborhood Hits	357	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX48_HUMAN
θ value	7.75577e-52 (rank : 29)	NC score	0.939233 (rank : 31)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	1.01294e-51 (rank : 30)	NC score	0.939023 (rank : 32)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

IF4A1_HUMAN
θ value	5.20228e-48 (rank : 31)	NC score	0.934467 (rank : 36)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	5.20228e-48 (rank : 32)	NC score	0.934467 (rank : 37)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

DDX39_MOUSE
θ value	1.51363e-47 (rank : 33)	NC score	0.932837 (rank : 42)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

IF4A2_HUMAN
θ value	2.58187e-47 (rank : 34)	NC score	0.934132 (rank : 38)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	2.58187e-47 (rank : 35)	NC score	0.934132 (rank : 39)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

UAP56_HUMAN
θ value	9.81109e-47 (rank : 36)	NC score	0.930859 (rank : 46)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

UAP56_MOUSE
θ value	9.81109e-47 (rank : 37)	NC score	0.930677 (rank : 48)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX50_MOUSE
θ value	1.28137e-46 (rank : 38)	NC score	0.936633 (rank : 34)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	106
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX39_HUMAN
θ value	2.18568e-46 (rank : 39)	NC score	0.932764 (rank : 43)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX50_HUMAN
θ value	2.18568e-46 (rank : 40)	NC score	0.935501 (rank : 35)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX27_HUMAN
θ value	6.35935e-46 (rank : 41)	NC score	0.943078 (rank : 29)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	124
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX21_HUMAN
θ value	3.15612e-45 (rank : 42)	NC score	0.931603 (rank : 44)
Query Neighborhood Hits	357	Target Neighborhood Hits	308	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX21_MOUSE
θ value	4.122e-45 (rank : 43)	NC score	0.924408 (rank : 53)
Query Neighborhood Hits	357	Target Neighborhood Hits	350	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX27_MOUSE
θ value	3.48949e-44 (rank : 44)	NC score	0.943492 (rank : 28)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	114
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX55_HUMAN
θ value	1.01529e-43 (rank : 45)	NC score	0.932918 (rank : 41)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX10_HUMAN
θ value	1.73182e-43 (rank : 46)	NC score	0.930761 (rank : 47)
Query Neighborhood Hits	357	Target Neighborhood Hits	210	Shared Neighborhood Hits	132
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX10_MOUSE
θ value	1.73182e-43 (rank : 47)	NC score	0.927648 (rank : 52)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	132
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX55_MOUSE
θ value	3.85808e-43 (rank : 48)	NC score	0.933773 (rank : 40)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX18_MOUSE
θ value	2.50074e-42 (rank : 49)	NC score	0.930548 (rank : 49)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX28_MOUSE
θ value	3.61106e-41 (rank : 50)	NC score	0.937038 (rank : 33)
Query Neighborhood Hits	357	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX31_HUMAN
θ value	6.15952e-41 (rank : 51)	NC score	0.931398 (rank : 45)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

DDX18_HUMAN
θ value	1.3722e-40 (rank : 52)	NC score	0.930456 (rank : 51)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX25_MOUSE
θ value	4.88048e-38 (rank : 53)	NC score	0.908835 (rank : 60)
Query Neighborhood Hits	357	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX25_HUMAN
θ value	2.05049e-36 (rank : 54)	NC score	0.909038 (rank : 58)
Query Neighborhood Hits	357	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX28_HUMAN
θ value	4.568e-36 (rank : 55)	NC score	0.930468 (rank : 50)
Query Neighborhood Hits	357	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX56_MOUSE
θ value	1.24399e-33 (rank : 56)	NC score	0.922316 (rank : 54)
Query Neighborhood Hits	357	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
θ value	1.79631e-32 (rank : 57)	NC score	0.921742 (rank : 55)
Query Neighborhood Hits	357	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DD19A_MOUSE
θ value	1.28732e-30 (rank : 58)	NC score	0.902344 (rank : 65)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DD19B_HUMAN
θ value	1.28732e-30 (rank : 59)	NC score	0.902557 (rank : 64)
Query Neighborhood Hits	357	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_HUMAN
θ value	2.19584e-30 (rank : 60)	NC score	0.903042 (rank : 63)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DDX51_MOUSE
θ value	3.74554e-30 (rank : 61)	NC score	0.908991 (rank : 59)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX20_HUMAN
θ value	8.3442e-30 (rank : 62)	NC score	0.911404 (rank : 56)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX20_MOUSE
θ value	1.85889e-29 (rank : 63)	NC score	0.908426 (rank : 61)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX51_HUMAN
θ value	4.14116e-29 (rank : 64)	NC score	0.895560 (rank : 66)
Query Neighborhood Hits	357	Target Neighborhood Hits	332	Shared Neighborhood Hits	109
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX24_MOUSE
θ value	4.57862e-28 (rank : 65)	NC score	0.909471 (rank : 57)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX24_HUMAN
θ value	5.97985e-28 (rank : 66)	NC score	0.907071 (rank : 62)
Query Neighborhood Hits	357	Target Neighborhood Hits	190	Shared Neighborhood Hits	100
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX1_MOUSE
θ value	4.43474e-23 (rank : 67)	NC score	0.872773 (rank : 67)
Query Neighborhood Hits	357	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
θ value	4.9032e-22 (rank : 68)	NC score	0.871139 (rank : 68)
Query Neighborhood Hits	357	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_MOUSE
θ value	4.16044e-13 (rank : 69)	NC score	0.588694 (rank : 70)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	90
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RECQ4_HUMAN
θ value	1.133e-10 (rank : 70)	NC score	0.596210 (rank : 69)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	92
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

WRN_MOUSE
θ value	5.62301e-10 (rank : 71)	NC score	0.497361 (rank : 75)
Query Neighborhood Hits	357	Target Neighborhood Hits	295	Shared Neighborhood Hits	125
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

WRN_HUMAN
θ value	1.63604e-09 (rank : 72)	NC score	0.518026 (rank : 73)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

BLM_MOUSE
θ value	2.13673e-09 (rank : 73)	NC score	0.541074 (rank : 71)
Query Neighborhood Hits	357	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
θ value	4.76016e-09 (rank : 74)	NC score	0.528471 (rank : 72)
Query Neighborhood Hits	357	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

RECQ5_HUMAN
θ value	4.0297e-08 (rank : 75)	NC score	0.511346 (rank : 74)
Query Neighborhood Hits	357	Target Neighborhood Hits	390	Shared Neighborhood Hits	91
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RECQ1_HUMAN
θ value	1.29631e-06 (rank : 76)	NC score	0.477536 (rank : 76)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

LGP2_HUMAN
θ value	3.77169e-06 (rank : 77)	NC score	0.358501 (rank : 84)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

NIPBL_HUMAN
θ value	4.92598e-06 (rank : 78)	NC score	0.101047 (rank : 94)
Query Neighborhood Hits	357	Target Neighborhood Hits	1311	Shared Neighborhood Hits	167
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CCD55_HUMAN
θ value	8.40245e-06 (rank : 79)	NC score	0.116809 (rank : 92)
Query Neighborhood Hits	357	Target Neighborhood Hits	513	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NPBL_MOUSE
θ value	2.44474e-05 (rank : 80)	NC score	0.098033 (rank : 96)
Query Neighborhood Hits	357	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

LGP2_MOUSE
θ value	3.19293e-05 (rank : 81)	NC score	0.372156 (rank : 82)
Query Neighborhood Hits	357	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

MRCKB_HUMAN
θ value	3.19293e-05 (rank : 82)	NC score	0.033451 (rank : 363)
Query Neighborhood Hits	357	Target Neighborhood Hits	2239	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RECQ1_MOUSE
θ value	5.44631e-05 (rank : 83)	NC score	0.475982 (rank : 77)
Query Neighborhood Hits	357	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RBBP6_HUMAN
θ value	7.1131e-05 (rank : 84)	NC score	0.091183 (rank : 100)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CI039_HUMAN
θ value	9.29e-05 (rank : 85)	NC score	0.076540 (rank : 116)
Query Neighborhood Hits	357	Target Neighborhood Hits	1171	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

TXND2_MOUSE
θ value	0.000121331 (rank : 86)	NC score	0.077318 (rank : 115)
Query Neighborhood Hits	357	Target Neighborhood Hits	828	Shared Neighborhood Hits	126
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

U520_HUMAN
θ value	0.000121331 (rank : 87)	NC score	0.178506 (rank : 88)
Query Neighborhood Hits	357	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

LEO1_HUMAN
θ value	0.000158464 (rank : 88)	NC score	0.083405 (rank : 105)
Query Neighborhood Hits	357	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MPP8_HUMAN
θ value	0.000158464 (rank : 89)	NC score	0.071079 (rank : 126)
Query Neighborhood Hits	357	Target Neighborhood Hits	948	Shared Neighborhood Hits	154
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MRCKB_MOUSE
θ value	0.000158464 (rank : 90)	NC score	0.032390 (rank : 367)
Query Neighborhood Hits	357	Target Neighborhood Hits	2180	Shared Neighborhood Hits	162
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

DDX58_HUMAN
θ value	0.000602161 (rank : 91)	NC score	0.218458 (rank : 87)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

RBM15_HUMAN
θ value	0.000602161 (rank : 92)	NC score	0.071432 (rank : 125)
Query Neighborhood Hits	357	Target Neighborhood Hits	309	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

SFRIP_HUMAN
θ value	0.000602161 (rank : 93)	NC score	0.097126 (rank : 97)
Query Neighborhood Hits	357	Target Neighborhood Hits	530	Shared Neighborhood Hits	81
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

LRRF2_HUMAN
θ value	0.000786445 (rank : 94)	NC score	0.066337 (rank : 145)
Query Neighborhood Hits	357	Target Neighborhood Hits	791	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

RRBP1_MOUSE
θ value	0.00102713 (rank : 95)	NC score	0.080980 (rank : 109)
Query Neighborhood Hits	357	Target Neighborhood Hits	1650	Shared Neighborhood Hits	193
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

DICER_MOUSE
θ value	0.00175202 (rank : 96)	NC score	0.411599 (rank : 80)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

RB15B_MOUSE
θ value	0.00228821 (rank : 97)	NC score	0.058373 (rank : 189)
Query Neighborhood Hits	357	Target Neighborhood Hits	284	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

DDX58_MOUSE
θ value	0.00298849 (rank : 98)	NC score	0.247506 (rank : 86)
Query Neighborhood Hits	357	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DICER_HUMAN
θ value	0.00298849 (rank : 99)	NC score	0.411478 (rank : 81)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

IFIH1_MOUSE
θ value	0.00298849 (rank : 100)	NC score	0.345837 (rank : 85)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

RRBP1_HUMAN
θ value	0.00298849 (rank : 101)	NC score	0.076077 (rank : 118)
Query Neighborhood Hits	357	Target Neighborhood Hits	1306	Shared Neighborhood Hits	178
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

NASP_HUMAN
θ value	0.00509761 (rank : 102)	NC score	0.071760 (rank : 124)
Query Neighborhood Hits	357	Target Neighborhood Hits	709	Shared Neighborhood Hits	121
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

FILA_HUMAN
θ value	0.00665767 (rank : 103)	NC score	0.078961 (rank : 113)
Query Neighborhood Hits	357	Target Neighborhood Hits	685	Shared Neighborhood Hits	70
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

IFIH1_HUMAN
θ value	0.00665767 (rank : 104)	NC score	0.359060 (rank : 83)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

TARA_MOUSE
θ value	0.00665767 (rank : 105)	NC score	0.067180 (rank : 140)
Query Neighborhood Hits	357	Target Neighborhood Hits	1133	Shared Neighborhood Hits	145
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

HELC1_HUMAN
θ value	0.00869519 (rank : 106)	NC score	0.144729 (rank : 90)
Query Neighborhood Hits	357	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

MYH4_MOUSE
θ value	0.00869519 (rank : 107)	NC score	0.059798 (rank : 176)
Query Neighborhood Hits	357	Target Neighborhood Hits	1476	Shared Neighborhood Hits	159
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
θ value	0.00869519 (rank : 108)	NC score	0.060412 (rank : 170)
Query Neighborhood Hits	357	Target Neighborhood Hits	1600	Shared Neighborhood Hits	168
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PPIG_HUMAN
θ value	0.00869519 (rank : 109)	NC score	0.076199 (rank : 117)
Query Neighborhood Hits	357	Target Neighborhood Hits	670	Shared Neighborhood Hits	162
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

GASP2_MOUSE
θ value	0.0113563 (rank : 110)	NC score	0.033755 (rank : 362)
Query Neighborhood Hits	357	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

LEO1_MOUSE
θ value	0.0113563 (rank : 111)	NC score	0.080279 (rank : 110)
Query Neighborhood Hits	357	Target Neighborhood Hits	946	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NOP14_HUMAN
θ value	0.0113563 (rank : 112)	NC score	0.083657 (rank : 104)
Query Neighborhood Hits	357	Target Neighborhood Hits	573	Shared Neighborhood Hits	131
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

ATRX_HUMAN
θ value	0.0148317 (rank : 113)	NC score	0.069596 (rank : 133)
Query Neighborhood Hits	357	Target Neighborhood Hits	842	Shared Neighborhood Hits	179
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

DHX34_MOUSE
θ value	0.0148317 (rank : 114)	NC score	0.025853 (rank : 388)
Query Neighborhood Hits	357	Target Neighborhood Hits	235	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

FANCM_HUMAN
θ value	0.0148317 (rank : 115)	NC score	0.427712 (rank : 78)
Query Neighborhood Hits	357	Target Neighborhood Hits	210	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

MAGI1_MOUSE
θ value	0.0148317 (rank : 116)	NC score	0.029805 (rank : 378)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

CK5P2_HUMAN
θ value	0.0252991 (rank : 117)	NC score	0.070825 (rank : 127)
Query Neighborhood Hits	357	Target Neighborhood Hits	1433	Shared Neighborhood Hits	181
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

FANCM_MOUSE
θ value	0.0252991 (rank : 118)	NC score	0.425517 (rank : 79)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

MAP1A_HUMAN
θ value	0.0252991 (rank : 119)	NC score	0.070107 (rank : 130)
Query Neighborhood Hits	357	Target Neighborhood Hits	1626	Shared Neighborhood Hits	191
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RBBP6_MOUSE
θ value	0.0252991 (rank : 120)	NC score	0.081227 (rank : 108)
Query Neighborhood Hits	357	Target Neighborhood Hits	1014	Shared Neighborhood Hits	136
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

GOGB1_HUMAN
θ value	0.0330416 (rank : 121)	NC score	0.064897 (rank : 152)
Query Neighborhood Hits	357	Target Neighborhood Hits	2297	Shared Neighborhood Hits	194
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KIF4A_HUMAN
θ value	0.0330416 (rank : 122)	NC score	0.048934 (rank : 317)
Query Neighborhood Hits	357	Target Neighborhood Hits	1159	Shared Neighborhood Hits	153
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MYH13_HUMAN
θ value	0.0330416 (rank : 123)	NC score	0.058198 (rank : 195)
Query Neighborhood Hits	357	Target Neighborhood Hits	1504	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ZC313_HUMAN
θ value	0.0330416 (rank : 124)	NC score	0.116708 (rank : 93)
Query Neighborhood Hits	357	Target Neighborhood Hits	772	Shared Neighborhood Hits	178
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CF060_HUMAN
θ value	0.0431538 (rank : 125)	NC score	0.065504 (rank : 147)
Query Neighborhood Hits	357	Target Neighborhood Hits	1270	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

IWS1_MOUSE
θ value	0.0431538 (rank : 126)	NC score	0.055844 (rank : 225)
Query Neighborhood Hits	357	Target Neighborhood Hits	1258	Shared Neighborhood Hits	105
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MCES_HUMAN
θ value	0.0431538 (rank : 127)	NC score	0.054126 (rank : 247)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	42
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

SCG2_HUMAN
θ value	0.0431538 (rank : 128)	NC score	0.041104 (rank : 343)
Query Neighborhood Hits	357	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CMGA_HUMAN
θ value	0.0563607 (rank : 129)	NC score	0.058702 (rank : 186)
Query Neighborhood Hits	357	Target Neighborhood Hits	238	Shared Neighborhood Hits	49
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

GOGA4_HUMAN
θ value	0.0563607 (rank : 130)	NC score	0.066505 (rank : 144)
Query Neighborhood Hits	357	Target Neighborhood Hits	2034	Shared Neighborhood Hits	195
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYH4_HUMAN
θ value	0.0563607 (rank : 131)	NC score	0.059379 (rank : 180)
Query Neighborhood Hits	357	Target Neighborhood Hits	1377	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

SMC3_HUMAN
θ value	0.0563607 (rank : 132)	NC score	0.063043 (rank : 160)
Query Neighborhood Hits	357	Target Neighborhood Hits	1186	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.0563607 (rank : 133)	NC score	0.063056 (rank : 159)
Query Neighborhood Hits	357	Target Neighborhood Hits	1187	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ZKSC1_HUMAN
θ value	0.0563607 (rank : 134)	NC score	-0.005326 (rank : 464)
Query Neighborhood Hits	357	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

CLCB_HUMAN
θ value	0.0736092 (rank : 135)	NC score	0.045457 (rank : 331)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	P09497, Q6FHW1	Gene names	CLTB
Domain Architecture
Description	Clathrin light chain B (Lcb).

LIPA1_HUMAN
θ value	0.0736092 (rank : 136)	NC score	0.057694 (rank : 202)
Query Neighborhood Hits	357	Target Neighborhood Hits	1294	Shared Neighborhood Hits	157
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

RBM6_HUMAN
θ value	0.0736092 (rank : 137)	NC score	0.036652 (rank : 355)
Query Neighborhood Hits	357	Target Neighborhood Hits	221	Shared Neighborhood Hits	30
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

TARA_HUMAN
θ value	0.0736092 (rank : 138)	NC score	0.058680 (rank : 188)
Query Neighborhood Hits	357	Target Neighborhood Hits	1626	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCD55_MOUSE
θ value	0.0961366 (rank : 139)	NC score	0.099820 (rank : 95)
Query Neighborhood Hits	357	Target Neighborhood Hits	519	Shared Neighborhood Hits	132
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CLCB_MOUSE
θ value	0.0961366 (rank : 140)	NC score	0.046498 (rank : 327)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

CTRO_MOUSE
θ value	0.0961366 (rank : 141)	NC score	0.031085 (rank : 374)
Query Neighborhood Hits	357	Target Neighborhood Hits	2344	Shared Neighborhood Hits	179
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

HSP74_MOUSE
θ value	0.0961366 (rank : 142)	NC score	0.028359 (rank : 382)
Query Neighborhood Hits	357	Target Neighborhood Hits	257	Shared Neighborhood Hits	75
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

NUF2_HUMAN
θ value	0.0961366 (rank : 143)	NC score	0.059796 (rank : 177)
Query Neighborhood Hits	357	Target Neighborhood Hits	661	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

RB15B_HUMAN
θ value	0.0961366 (rank : 144)	NC score	0.049923 (rank : 316)
Query Neighborhood Hits	357	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

SLK_MOUSE
θ value	0.0961366 (rank : 145)	NC score	0.016284 (rank : 421)
Query Neighborhood Hits	357	Target Neighborhood Hits	1798	Shared Neighborhood Hits	160
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TCAL5_HUMAN
θ value	0.0961366 (rank : 146)	NC score	0.052983 (rank : 265)
Query Neighborhood Hits	357	Target Neighborhood Hits	806	Shared Neighborhood Hits	95
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

YLPM1_HUMAN
θ value	0.0961366 (rank : 147)	NC score	0.035846 (rank : 358)
Query Neighborhood Hits	357	Target Neighborhood Hits	670	Shared Neighborhood Hits	49
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

KINH_MOUSE
θ value	0.125558 (rank : 148)	NC score	0.048359 (rank : 320)
Query Neighborhood Hits	357	Target Neighborhood Hits	1082	Shared Neighborhood Hits	159
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LUZP1_MOUSE
θ value	0.125558 (rank : 149)	NC score	0.067155 (rank : 141)
Query Neighborhood Hits	357	Target Neighborhood Hits	940	Shared Neighborhood Hits	157
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MY18A_HUMAN
θ value	0.125558 (rank : 150)	NC score	0.064961 (rank : 150)
Query Neighborhood Hits	357	Target Neighborhood Hits	1929	Shared Neighborhood Hits	196
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	0.125558 (rank : 151)	NC score	0.066782 (rank : 142)
Query Neighborhood Hits	357	Target Neighborhood Hits	1989	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH3_HUMAN
θ value	0.125558 (rank : 152)	NC score	0.061023 (rank : 168)
Query Neighborhood Hits	357	Target Neighborhood Hits	1660	Shared Neighborhood Hits	170
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NSBP1_MOUSE
θ value	0.125558 (rank : 153)	NC score	0.062018 (rank : 162)
Query Neighborhood Hits	357	Target Neighborhood Hits	681	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PLCB1_HUMAN
θ value	0.125558 (rank : 154)	NC score	0.045075 (rank : 332)
Query Neighborhood Hits	357	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SLK_HUMAN
θ value	0.125558 (rank : 155)	NC score	0.015746 (rank : 424)
Query Neighborhood Hits	357	Target Neighborhood Hits	1775	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TR150_HUMAN
θ value	0.125558 (rank : 156)	NC score	0.061800 (rank : 164)
Query Neighborhood Hits	357	Target Neighborhood Hits	313	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

WDHD1_MOUSE
θ value	0.125558 (rank : 157)	NC score	0.017803 (rank : 413)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

XYLT1_MOUSE
θ value	0.125558 (rank : 158)	NC score	0.025050 (rank : 389)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

ANR11_HUMAN
θ value	0.163984 (rank : 159)	NC score	0.040605 (rank : 345)
Query Neighborhood Hits	357	Target Neighborhood Hits	1289	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CAC1A_HUMAN
θ value	0.163984 (rank : 160)	NC score	0.012690 (rank : 433)
Query Neighborhood Hits	357	Target Neighborhood Hits	387	Shared Neighborhood Hits	33
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CT2NL_HUMAN
θ value	0.163984 (rank : 161)	NC score	0.070418 (rank : 128)
Query Neighborhood Hits	357	Target Neighborhood Hits	1059	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

E41L1_HUMAN
θ value	0.163984 (rank : 162)	NC score	0.014353 (rank : 429)
Query Neighborhood Hits	357	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

KI21A_HUMAN
θ value	0.163984 (rank : 163)	NC score	0.042662 (rank : 339)
Query Neighborhood Hits	357	Target Neighborhood Hits	1543	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

LMD1_HUMAN
θ value	0.163984 (rank : 164)	NC score	0.050443 (rank : 310)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MAGI1_HUMAN
θ value	0.163984 (rank : 165)	NC score	0.023037 (rank : 396)
Query Neighborhood Hits	357	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

STMN1_MOUSE
θ value	0.163984 (rank : 166)	NC score	0.056749 (rank : 212)
Query Neighborhood Hits	357	Target Neighborhood Hits	560	Shared Neighborhood Hits	110
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

MYH9_MOUSE
θ value	0.21417 (rank : 167)	NC score	0.061994 (rank : 163)
Query Neighborhood Hits	357	Target Neighborhood Hits	1829	Shared Neighborhood Hits	183
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RPTN_MOUSE
θ value	0.21417 (rank : 168)	NC score	0.051705 (rank : 287)
Query Neighborhood Hits	357	Target Neighborhood Hits	650	Shared Neighborhood Hits	82
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

STMN1_HUMAN
θ value	0.21417 (rank : 169)	NC score	0.056116 (rank : 217)
Query Neighborhood Hits	357	Target Neighborhood Hits	554	Shared Neighborhood Hits	109
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

SYCP1_MOUSE
θ value	0.21417 (rank : 170)	NC score	0.063963 (rank : 157)
Query Neighborhood Hits	357	Target Neighborhood Hits	1456	Shared Neighborhood Hits	169
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CP135_MOUSE
θ value	0.279714 (rank : 171)	NC score	0.057225 (rank : 207)
Query Neighborhood Hits	357	Target Neighborhood Hits	1278	Shared Neighborhood Hits	152
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SMRC1_MOUSE
θ value	0.279714 (rank : 172)	NC score	0.038868 (rank : 350)
Query Neighborhood Hits	357	Target Neighborhood Hits	459	Shared Neighborhood Hits	89
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

TCRG1_HUMAN
θ value	0.279714 (rank : 173)	NC score	0.064589 (rank : 154)
Query Neighborhood Hits	357	Target Neighborhood Hits	929	Shared Neighborhood Hits	148
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	0.279714 (rank : 174)	NC score	0.064763 (rank : 153)
Query Neighborhood Hits	357	Target Neighborhood Hits	947	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

DMD_MOUSE
θ value	0.365318 (rank : 175)	NC score	0.047099 (rank : 325)
Query Neighborhood Hits	357	Target Neighborhood Hits	1111	Shared Neighborhood Hits	144
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

MYH10_MOUSE
θ value	0.365318 (rank : 176)	NC score	0.056896 (rank : 210)
Query Neighborhood Hits	357	Target Neighborhood Hits	1612	Shared Neighborhood Hits	167
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SDCG8_HUMAN
θ value	0.365318 (rank : 177)	NC score	0.056007 (rank : 223)
Query Neighborhood Hits	357	Target Neighborhood Hits	1002	Shared Neighborhood Hits	141
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

FLIP1_HUMAN
θ value	0.47712 (rank : 178)	NC score	0.062495 (rank : 161)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	168
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LIPA2_MOUSE
θ value	0.47712 (rank : 179)	NC score	0.055104 (rank : 239)
Query Neighborhood Hits	357	Target Neighborhood Hits	1282	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MATR3_HUMAN
θ value	0.47712 (rank : 180)	NC score	0.036917 (rank : 354)
Query Neighborhood Hits	357	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MYH10_HUMAN
θ value	0.47712 (rank : 181)	NC score	0.057025 (rank : 209)
Query Neighborhood Hits	357	Target Neighborhood Hits	1620	Shared Neighborhood Hits	165
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
θ value	0.47712 (rank : 182)	NC score	0.060568 (rank : 169)
Query Neighborhood Hits	357	Target Neighborhood Hits	1762	Shared Neighborhood Hits	182
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PACN3_HUMAN
θ value	0.47712 (rank : 183)	NC score	0.020495 (rank : 404)
Query Neighborhood Hits	357	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SYNE2_HUMAN
θ value	0.47712 (rank : 184)	NC score	0.046442 (rank : 328)
Query Neighborhood Hits	357	Target Neighborhood Hits	1323	Shared Neighborhood Hits	153
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TAOK1_HUMAN
θ value	0.47712 (rank : 185)	NC score	0.018091 (rank : 411)
Query Neighborhood Hits	357	Target Neighborhood Hits	1734	Shared Neighborhood Hits	152
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

ZN277_HUMAN
θ value	0.47712 (rank : 186)	NC score	0.026377 (rank : 385)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRM2	Gene names	ZNF277
Domain Architecture	No domain graphic available
Description	Zinc finger protein 277.

CHD9_MOUSE
θ value	0.62314 (rank : 187)	NC score	0.026404 (rank : 384)
Query Neighborhood Hits	357	Target Neighborhood Hits	427	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CING_MOUSE
θ value	0.62314 (rank : 188)	NC score	0.061372 (rank : 166)
Query Neighborhood Hits	357	Target Neighborhood Hits	1432	Shared Neighborhood Hits	162
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

GOGA2_MOUSE
θ value	0.62314 (rank : 189)	NC score	0.051163 (rank : 299)
Query Neighborhood Hits	357	Target Neighborhood Hits	944	Shared Neighborhood Hits	124
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

KINH_HUMAN
θ value	0.62314 (rank : 190)	NC score	0.048687 (rank : 318)
Query Neighborhood Hits	357	Target Neighborhood Hits	1231	Shared Neighborhood Hits	157
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MYH11_MOUSE
θ value	0.62314 (rank : 191)	NC score	0.059232 (rank : 181)
Query Neighborhood Hits	357	Target Neighborhood Hits	1777	Shared Neighborhood Hits	185
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NUFP1_MOUSE
θ value	0.62314 (rank : 192)	NC score	0.014326 (rank : 430)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

PF21B_HUMAN
θ value	0.62314 (rank : 193)	NC score	0.016407 (rank : 420)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF20_MOUSE
θ value	0.62314 (rank : 194)	NC score	0.056100 (rank : 219)
Query Neighborhood Hits	357	Target Neighborhood Hits	513	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PLCB1_MOUSE
θ value	0.62314 (rank : 195)	NC score	0.042540 (rank : 340)
Query Neighborhood Hits	357	Target Neighborhood Hits	531	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SMRC1_HUMAN
θ value	0.62314 (rank : 196)	NC score	0.036958 (rank : 353)
Query Neighborhood Hits	357	Target Neighborhood Hits	375	Shared Neighborhood Hits	74
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

STK10_MOUSE
θ value	0.62314 (rank : 197)	NC score	0.023810 (rank : 393)
Query Neighborhood Hits	357	Target Neighborhood Hits	2132	Shared Neighborhood Hits	184
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CCD21_HUMAN
θ value	0.813845 (rank : 198)	NC score	0.055891 (rank : 224)
Query Neighborhood Hits	357	Target Neighborhood Hits	1228	Shared Neighborhood Hits	152
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

DMP1_HUMAN
θ value	0.813845 (rank : 199)	NC score	0.067719 (rank : 138)
Query Neighborhood Hits	357	Target Neighborhood Hits	491	Shared Neighborhood Hits	75
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

GOGA5_MOUSE
θ value	0.813845 (rank : 200)	NC score	0.056130 (rank : 216)
Query Neighborhood Hits	357	Target Neighborhood Hits	1434	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MYH11_HUMAN
θ value	0.813845 (rank : 201)	NC score	0.057610 (rank : 204)
Query Neighborhood Hits	357	Target Neighborhood Hits	1806	Shared Neighborhood Hits	184
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RFIP4_HUMAN
θ value	0.813845 (rank : 202)	NC score	0.048304 (rank : 321)
Query Neighborhood Hits	357	Target Neighborhood Hits	785	Shared Neighborhood Hits	122
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SNW1_HUMAN
θ value	0.813845 (rank : 203)	NC score	0.042530 (rank : 341)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
θ value	0.813845 (rank : 204)	NC score	0.042378 (rank : 342)
Query Neighborhood Hits	357	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

SP110_HUMAN
θ value	0.813845 (rank : 205)	NC score	0.019862 (rank : 407)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TAOK1_MOUSE
θ value	0.813845 (rank : 206)	NC score	0.017447 (rank : 415)
Query Neighborhood Hits	357	Target Neighborhood Hits	1720	Shared Neighborhood Hits	150
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

UACA_HUMAN
θ value	0.813845 (rank : 207)	NC score	0.043916 (rank : 335)
Query Neighborhood Hits	357	Target Neighborhood Hits	1622	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CI093_HUMAN
θ value	1.06291 (rank : 208)	NC score	0.063388 (rank : 158)
Query Neighborhood Hits	357	Target Neighborhood Hits	1088	Shared Neighborhood Hits	144
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CROCC_MOUSE
θ value	1.06291 (rank : 209)	NC score	0.056051 (rank : 221)
Query Neighborhood Hits	357	Target Neighborhood Hits	1460	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DMN_HUMAN
θ value	1.06291 (rank : 210)	NC score	0.031126 (rank : 372)
Query Neighborhood Hits	357	Target Neighborhood Hits	690	Shared Neighborhood Hits	122
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

GP179_HUMAN
θ value	1.06291 (rank : 211)	NC score	0.020492 (rank : 405)
Query Neighborhood Hits	357	Target Neighborhood Hits	372	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

HOME2_MOUSE
θ value	1.06291 (rank : 212)	NC score	0.047492 (rank : 324)
Query Neighborhood Hits	357	Target Neighborhood Hits	882	Shared Neighborhood Hits	135
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

SYCP1_HUMAN
θ value	1.06291 (rank : 213)	NC score	0.061632 (rank : 165)
Query Neighborhood Hits	357	Target Neighborhood Hits	1313	Shared Neighborhood Hits	160
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TCAL3_MOUSE
θ value	1.06291 (rank : 214)	NC score	0.039691 (rank : 349)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

EEA1_HUMAN
θ value	1.38821 (rank : 215)	NC score	0.052510 (rank : 270)
Query Neighborhood Hits	357	Target Neighborhood Hits	1796	Shared Neighborhood Hits	163
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ITSN1_MOUSE
θ value	1.38821 (rank : 216)	NC score	0.034840 (rank : 360)
Query Neighborhood Hits	357	Target Neighborhood Hits	1669	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYH1_HUMAN
θ value	1.38821 (rank : 217)	NC score	0.059124 (rank : 183)
Query Neighborhood Hits	357	Target Neighborhood Hits	1478	Shared Neighborhood Hits	163
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	1.38821 (rank : 218)	NC score	0.058972 (rank : 185)
Query Neighborhood Hits	357	Target Neighborhood Hits	1461	Shared Neighborhood Hits	161
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	1.38821 (rank : 219)	NC score	0.058290 (rank : 192)
Query Neighborhood Hits	357	Target Neighborhood Hits	1491	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH6_MOUSE
θ value	1.38821 (rank : 220)	NC score	0.057724 (rank : 201)
Query Neighborhood Hits	357	Target Neighborhood Hits	1501	Shared Neighborhood Hits	162
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_HUMAN
θ value	1.38821 (rank : 221)	NC score	0.060221 (rank : 172)
Query Neighborhood Hits	357	Target Neighborhood Hits	1610	Shared Neighborhood Hits	174
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PCLO_MOUSE
θ value	1.38821 (rank : 222)	NC score	0.020634 (rank : 403)
Query Neighborhood Hits	357	Target Neighborhood Hits	2275	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PPIP2_MOUSE
θ value	1.38821 (rank : 223)	NC score	0.033300 (rank : 364)
Query Neighborhood Hits	357	Target Neighborhood Hits	308	Shared Neighborhood Hits	79
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

PRP16_HUMAN
θ value	1.38821 (rank : 224)	NC score	0.032064 (rank : 369)
Query Neighborhood Hits	357	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

SEC63_HUMAN
θ value	1.38821 (rank : 225)	NC score	0.030204 (rank : 376)
Query Neighborhood Hits	357	Target Neighborhood Hits	586	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SETD8_MOUSE
θ value	1.38821 (rank : 226)	NC score	0.012409 (rank : 435)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

TR150_MOUSE
θ value	1.38821 (rank : 227)	NC score	0.059064 (rank : 184)
Query Neighborhood Hits	357	Target Neighborhood Hits	468	Shared Neighborhood Hits	80
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

XYLT1_HUMAN
θ value	1.38821 (rank : 228)	NC score	0.015892 (rank : 422)
Query Neighborhood Hits	357	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

ZN318_MOUSE
θ value	1.38821 (rank : 229)	NC score	0.043279 (rank : 338)
Query Neighborhood Hits	357	Target Neighborhood Hits	642	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ADDB_MOUSE
θ value	1.81305 (rank : 230)	NC score	0.025987 (rank : 387)
Query Neighborhood Hits	357	Target Neighborhood Hits	574	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CK5P2_MOUSE
θ value	1.81305 (rank : 231)	NC score	0.066708 (rank : 143)
Query Neighborhood Hits	357	Target Neighborhood Hits	1151	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DHX36_HUMAN
θ value	1.81305 (rank : 232)	NC score	0.024352 (rank : 391)
Query Neighborhood Hits	357	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

GOGA4_MOUSE
θ value	1.81305 (rank : 233)	NC score	0.059816 (rank : 175)
Query Neighborhood Hits	357	Target Neighborhood Hits	1939	Shared Neighborhood Hits	194
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LRC27_HUMAN
θ value	1.81305 (rank : 234)	NC score	0.023345 (rank : 395)
Query Neighborhood Hits	357	Target Neighborhood Hits	710	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

SRRM2_HUMAN
θ value	1.81305 (rank : 235)	NC score	0.048025 (rank : 322)
Query Neighborhood Hits	357	Target Neighborhood Hits	1296	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ADDB_HUMAN
θ value	2.36792 (rank : 236)	NC score	0.014991 (rank : 426)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	26
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

CHCH3_MOUSE
θ value	2.36792 (rank : 237)	NC score	0.031845 (rank : 371)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

GRP78_HUMAN
θ value	2.36792 (rank : 238)	NC score	0.014172 (rank : 431)
Query Neighborhood Hits	357	Target Neighborhood Hits	218	Shared Neighborhood Hits	54
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	2.36792 (rank : 239)	NC score	0.014006 (rank : 432)
Query Neighborhood Hits	357	Target Neighborhood Hits	216	Shared Neighborhood Hits	52
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

PERQ1_MOUSE
θ value	2.36792 (rank : 240)	NC score	0.030428 (rank : 375)
Query Neighborhood Hits	357	Target Neighborhood Hits	215	Shared Neighborhood Hits	57
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

SRRM2_MOUSE
θ value	2.36792 (rank : 241)	NC score	0.045945 (rank : 330)
Query Neighborhood Hits	357	Target Neighborhood Hits	1470	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

UBP1_HUMAN
θ value	2.36792 (rank : 242)	NC score	0.019559 (rank : 408)
Query Neighborhood Hits	357	Target Neighborhood Hits	259	Shared Neighborhood Hits	51
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP8_HUMAN
θ value	2.36792 (rank : 243)	NC score	0.028480 (rank : 381)
Query Neighborhood Hits	357	Target Neighborhood Hits	751	Shared Neighborhood Hits	153
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

XPC_MOUSE
θ value	2.36792 (rank : 244)	NC score	0.018901 (rank : 409)
Query Neighborhood Hits	357	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

CCD46_HUMAN
θ value	3.0926 (rank : 245)	NC score	0.059153 (rank : 182)
Query Neighborhood Hits	357	Target Neighborhood Hits	1430	Shared Neighborhood Hits	153
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	3.0926 (rank : 246)	NC score	0.060015 (rank : 173)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	170
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD91_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.051444 (rank : 292)
Query Neighborhood Hits	357	Target Neighborhood Hits	868	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CN145_HUMAN
θ value	3.0926 (rank : 248)	NC score	0.056139 (rank : 215)
Query Neighborhood Hits	357	Target Neighborhood Hits	1196	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DIAP2_MOUSE
θ value	3.0926 (rank : 249)	NC score	0.010101 (rank : 443)
Query Neighborhood Hits	357	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

FLIP1_MOUSE
θ value	3.0926 (rank : 250)	NC score	0.059688 (rank : 178)
Query Neighborhood Hits	357	Target Neighborhood Hits	1176	Shared Neighborhood Hits	151
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA5_HUMAN
θ value	3.0926 (rank : 251)	NC score	0.053924 (rank : 249)
Query Neighborhood Hits	357	Target Neighborhood Hits	1168	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

IWS1_HUMAN
θ value	3.0926 (rank : 252)	NC score	0.057770 (rank : 200)
Query Neighborhood Hits	357	Target Neighborhood Hits	1241	Shared Neighborhood Hits	130
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KTN1_MOUSE
θ value	3.0926 (rank : 253)	NC score	0.059937 (rank : 174)
Query Neighborhood Hits	357	Target Neighborhood Hits	1324	Shared Neighborhood Hits	164
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

NKTR_HUMAN
θ value	3.0926 (rank : 254)	NC score	0.048458 (rank : 319)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	113
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

OCLN_HUMAN
θ value	3.0926 (rank : 255)	NC score	0.016887 (rank : 416)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

PACN3_MOUSE
θ value	3.0926 (rank : 256)	NC score	0.014449 (rank : 428)
Query Neighborhood Hits	357	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

RB6I2_HUMAN
θ value	3.0926 (rank : 257)	NC score	0.058694 (rank : 187)
Query Neighborhood Hits	357	Target Neighborhood Hits	1584	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RIMS1_HUMAN
θ value	3.0926 (rank : 258)	NC score	0.011038 (rank : 439)
Query Neighborhood Hits	357	Target Neighborhood Hits	437	Shared Neighborhood Hits	36
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RPTN_HUMAN
θ value	3.0926 (rank : 259)	NC score	0.036419 (rank : 356)
Query Neighborhood Hits	357	Target Neighborhood Hits	406	Shared Neighborhood Hits	56
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

SAFB2_HUMAN
θ value	3.0926 (rank : 260)	NC score	0.053914 (rank : 250)
Query Neighborhood Hits	357	Target Neighborhood Hits	720	Shared Neighborhood Hits	152
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SEC63_MOUSE
θ value	3.0926 (rank : 261)	NC score	0.027734 (rank : 383)
Query Neighborhood Hits	357	Target Neighborhood Hits	601	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TCAL6_HUMAN
θ value	3.0926 (rank : 262)	NC score	0.036227 (rank : 357)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

TTLL5_MOUSE
θ value	3.0926 (rank : 263)	NC score	0.006549 (rank : 452)
Query Neighborhood Hits	357	Target Neighborhood Hits	150	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

AKAP6_HUMAN
θ value	4.03905 (rank : 264)	NC score	0.032208 (rank : 368)
Query Neighborhood Hits	357	Target Neighborhood Hits	263	Shared Neighborhood Hits	55
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CP250_HUMAN
θ value	4.03905 (rank : 265)	NC score	0.053112 (rank : 258)
Query Neighborhood Hits	357	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DESP_HUMAN
θ value	4.03905 (rank : 266)	NC score	0.055588 (rank : 226)
Query Neighborhood Hits	357	Target Neighborhood Hits	1470	Shared Neighborhood Hits	161
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DNMT1_HUMAN
θ value	4.03905 (rank : 267)	NC score	0.044834 (rank : 333)
Query Neighborhood Hits	357	Target Neighborhood Hits	401	Shared Neighborhood Hits	93
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

EEA1_MOUSE
θ value	4.03905 (rank : 268)	NC score	0.055119 (rank : 238)
Query Neighborhood Hits	357	Target Neighborhood Hits	1637	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

EP15_MOUSE
θ value	4.03905 (rank : 269)	NC score	0.040010 (rank : 347)
Query Neighborhood Hits	357	Target Neighborhood Hits	820	Shared Neighborhood Hits	119
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERC2_MOUSE
θ value	4.03905 (rank : 270)	NC score	0.054727 (rank : 244)
Query Neighborhood Hits	357	Target Neighborhood Hits	1166	Shared Neighborhood Hits	148
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

HSP74_HUMAN
θ value	4.03905 (rank : 271)	NC score	0.015876 (rank : 423)
Query Neighborhood Hits	357	Target Neighborhood Hits	154	Shared Neighborhood Hits	49
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

JIP3_MOUSE
θ value	4.03905 (rank : 272)	NC score	0.030030 (rank : 377)
Query Neighborhood Hits	357	Target Neighborhood Hits	759	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

K1718_HUMAN
θ value	4.03905 (rank : 273)	NC score	0.007897 (rank : 448)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

KTN1_HUMAN
θ value	4.03905 (rank : 274)	NC score	0.054938 (rank : 241)
Query Neighborhood Hits	357	Target Neighborhood Hits	1197	Shared Neighborhood Hits	146
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MYH7_HUMAN
θ value	4.03905 (rank : 275)	NC score	0.057394 (rank : 206)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	165
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NEST_HUMAN
θ value	4.03905 (rank : 276)	NC score	0.051588 (rank : 289)
Query Neighborhood Hits	357	Target Neighborhood Hits	1305	Shared Neighborhood Hits	165
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

OCLN_MOUSE
θ value	4.03905 (rank : 277)	NC score	0.016820 (rank : 417)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q61146, Q544A7	Gene names	Ocln, Ocl
Domain Architecture
Description	Occludin.

OPTN_HUMAN
θ value	4.03905 (rank : 278)	NC score	0.050794 (rank : 304)
Query Neighborhood Hits	357	Target Neighborhood Hits	827	Shared Neighborhood Hits	138
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PDCL3_MOUSE
θ value	4.03905 (rank : 279)	NC score	0.006667 (rank : 451)
Query Neighborhood Hits	357	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

ROCK1_MOUSE
θ value	4.03905 (rank : 280)	NC score	0.026155 (rank : 386)
Query Neighborhood Hits	357	Target Neighborhood Hits	2126	Shared Neighborhood Hits	163
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SMC1A_HUMAN
θ value	4.03905 (rank : 281)	NC score	0.057490 (rank : 205)
Query Neighborhood Hits	357	Target Neighborhood Hits	1346	Shared Neighborhood Hits	173
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	4.03905 (rank : 282)	NC score	0.057790 (rank : 199)
Query Neighborhood Hits	357	Target Neighborhood Hits	1384	Shared Neighborhood Hits	171
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TMC2_MOUSE
θ value	4.03905 (rank : 283)	NC score	0.024029 (rank : 392)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TRI29_MOUSE
θ value	4.03905 (rank : 284)	NC score	0.014457 (rank : 427)
Query Neighborhood Hits	357	Target Neighborhood Hits	306	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

UBP8_MOUSE
θ value	4.03905 (rank : 285)	NC score	0.017899 (rank : 412)
Query Neighborhood Hits	357	Target Neighborhood Hits	362	Shared Neighborhood Hits	84
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

YETS2_HUMAN
θ value	4.03905 (rank : 286)	NC score	0.007444 (rank : 450)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

YTDC1_HUMAN
θ value	4.03905 (rank : 287)	NC score	0.056648 (rank : 213)
Query Neighborhood Hits	357	Target Neighborhood Hits	458	Shared Neighborhood Hits	100
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ANR12_HUMAN
θ value	5.27518 (rank : 288)	NC score	0.046022 (rank : 329)
Query Neighborhood Hits	357	Target Neighborhood Hits	1081	Shared Neighborhood Hits	172
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BRD7_MOUSE
θ value	5.27518 (rank : 289)	NC score	0.005605 (rank : 453)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

CING_HUMAN
θ value	5.27518 (rank : 290)	NC score	0.058313 (rank : 190)
Query Neighborhood Hits	357	Target Neighborhood Hits	1275	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CJ078_MOUSE
θ value	5.27518 (rank : 291)	NC score	0.029454 (rank : 379)
Query Neighborhood Hits	357	Target Neighborhood Hits	559	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

DCDC2_HUMAN
θ value	5.27518 (rank : 292)	NC score	0.008653 (rank : 446)
Query Neighborhood Hits	357	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

DIDO1_HUMAN
θ value	5.27518 (rank : 293)	NC score	0.022667 (rank : 398)
Query Neighborhood Hits	357	Target Neighborhood Hits	960	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

EP15_HUMAN
θ value	5.27518 (rank : 294)	NC score	0.039847 (rank : 348)
Query Neighborhood Hits	357	Target Neighborhood Hits	1021	Shared Neighborhood Hits	135
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERC2_HUMAN
θ value	5.27518 (rank : 295)	NC score	0.054202 (rank : 246)
Query Neighborhood Hits	357	Target Neighborhood Hits	1156	Shared Neighborhood Hits	146
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

EST1A_MOUSE
θ value	5.27518 (rank : 296)	NC score	0.015136 (rank : 425)
Query Neighborhood Hits	357	Target Neighborhood Hits	138	Shared Neighborhood Hits	30
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

GCC2_MOUSE
θ value	5.27518 (rank : 297)	NC score	0.055147 (rank : 235)
Query Neighborhood Hits	357	Target Neighborhood Hits	1619	Shared Neighborhood Hits	172
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

HELI_MOUSE
θ value	5.27518 (rank : 298)	NC score	-0.008332 (rank : 465)
Query Neighborhood Hits	357	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

IF2M_MOUSE
θ value	5.27518 (rank : 299)	NC score	0.010239 (rank : 441)
Query Neighborhood Hits	357	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

KIF4A_MOUSE
θ value	5.27518 (rank : 300)	NC score	0.037598 (rank : 352)
Query Neighborhood Hits	357	Target Neighborhood Hits	1033	Shared Neighborhood Hits	142
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MATR3_MOUSE
θ value	5.27518 (rank : 301)	NC score	0.038378 (rank : 351)
Query Neighborhood Hits	357	Target Neighborhood Hits	321	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

MDN1_HUMAN
θ value	5.27518 (rank : 302)	NC score	0.044775 (rank : 334)
Query Neighborhood Hits	357	Target Neighborhood Hits	662	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MYO5C_HUMAN
θ value	5.27518 (rank : 303)	NC score	0.051875 (rank : 279)
Query Neighborhood Hits	357	Target Neighborhood Hits	1206	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NIN_HUMAN
θ value	5.27518 (rank : 304)	NC score	0.052388 (rank : 271)
Query Neighborhood Hits	357	Target Neighborhood Hits	1416	Shared Neighborhood Hits	158
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NUCL_HUMAN
θ value	5.27518 (rank : 305)	NC score	0.017749 (rank : 414)
Query Neighborhood Hits	357	Target Neighborhood Hits	415	Shared Neighborhood Hits	49
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

PARP2_HUMAN
θ value	5.27518 (rank : 306)	NC score	0.008296 (rank : 447)
Query Neighborhood Hits	357	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PINX1_HUMAN
θ value	5.27518 (rank : 307)	NC score	0.008808 (rank : 445)
Query Neighborhood Hits	357	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

PLCB4_HUMAN
θ value	5.27518 (rank : 308)	NC score	0.047492 (rank : 323)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	134
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

SURF6_HUMAN
θ value	5.27518 (rank : 309)	NC score	0.020787 (rank : 402)
Query Neighborhood Hits	357	Target Neighborhood Hits	104	Shared Neighborhood Hits	30
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

SVIL_MOUSE
θ value	5.27518 (rank : 310)	NC score	0.011973 (rank : 436)
Query Neighborhood Hits	357	Target Neighborhood Hits	439	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TUFT1_HUMAN
θ value	5.27518 (rank : 311)	NC score	0.046550 (rank : 326)
Query Neighborhood Hits	357	Target Neighborhood Hits	686	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

UBXD2_MOUSE
θ value	5.27518 (rank : 312)	NC score	0.021237 (rank : 401)
Query Neighborhood Hits	357	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

APOA1_HUMAN
θ value	6.88961 (rank : 313)	NC score	0.028906 (rank : 380)
Query Neighborhood Hits	357	Target Neighborhood Hits	262	Shared Neighborhood Hits	61
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

CLCA_HUMAN
θ value	6.88961 (rank : 314)	NC score	0.022953 (rank : 397)
Query Neighborhood Hits	357	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

EZRI_HUMAN
θ value	6.88961 (rank : 315)	NC score	0.031097 (rank : 373)
Query Neighborhood Hits	357	Target Neighborhood Hits	663	Shared Neighborhood Hits	133
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FMN1B_MOUSE
θ value	6.88961 (rank : 316)	NC score	0.012418 (rank : 434)
Query Neighborhood Hits	357	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GASP1_MOUSE
θ value	6.88961 (rank : 317)	NC score	0.016727 (rank : 419)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

IF4B_HUMAN
θ value	6.88961 (rank : 318)	NC score	0.018810 (rank : 410)
Query Neighborhood Hits	357	Target Neighborhood Hits	417	Shared Neighborhood Hits	32
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IFT81_HUMAN
θ value	6.88961 (rank : 319)	NC score	0.052359 (rank : 272)
Query Neighborhood Hits	357	Target Neighborhood Hits	893	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

MYH14_MOUSE
θ value	6.88961 (rank : 320)	NC score	0.056109 (rank : 218)
Query Neighborhood Hits	357	Target Neighborhood Hits	1225	Shared Neighborhood Hits	156
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYPT1_MOUSE
θ value	6.88961 (rank : 321)	NC score	0.008964 (rank : 444)
Query Neighborhood Hits	357	Target Neighborhood Hits	539	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PEPL_MOUSE
θ value	6.88961 (rank : 322)	NC score	0.050574 (rank : 309)
Query Neighborhood Hits	357	Target Neighborhood Hits	1105	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PIBF1_HUMAN
θ value	6.88961 (rank : 323)	NC score	0.058298 (rank : 191)
Query Neighborhood Hits	357	Target Neighborhood Hits	1041	Shared Neighborhood Hits	142
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PLK4_HUMAN
θ value	6.88961 (rank : 324)	NC score	-0.004473 (rank : 463)
Query Neighborhood Hits	357	Target Neighborhood Hits	884	Shared Neighborhood Hits	20
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PPIL4_HUMAN
θ value	6.88961 (rank : 325)	NC score	0.010256 (rank : 440)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

REST_HUMAN
θ value	6.88961 (rank : 326)	NC score	0.053594 (rank : 252)
Query Neighborhood Hits	357	Target Neighborhood Hits	1605	Shared Neighborhood Hits	171
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ROCK1_HUMAN
θ value	6.88961 (rank : 327)	NC score	0.022044 (rank : 399)
Query Neighborhood Hits	357	Target Neighborhood Hits	2000	Shared Neighborhood Hits	151
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SPEG_HUMAN
θ value	6.88961 (rank : 328)	NC score	-0.003278 (rank : 462)
Query Neighborhood Hits	357	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	6.88961 (rank : 329)	NC score	-0.001557 (rank : 460)
Query Neighborhood Hits	357	Target Neighborhood Hits	1959	Shared Neighborhood Hits	56
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRBS1_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.003333 (rank : 454)
Query Neighborhood Hits	357	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STIM1_HUMAN
θ value	6.88961 (rank : 331)	NC score	0.043396 (rank : 337)
Query Neighborhood Hits	357	Target Neighborhood Hits	665	Shared Neighborhood Hits	119
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_MOUSE
θ value	6.88961 (rank : 332)	NC score	0.043847 (rank : 336)
Query Neighborhood Hits	357	Target Neighborhood Hits	660	Shared Neighborhood Hits	123
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM2_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.032749 (rank : 365)
Query Neighborhood Hits	357	Target Neighborhood Hits	420	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

TTC16_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.034819 (rank : 361)
Query Neighborhood Hits	357	Target Neighborhood Hits	417	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ABCA2_HUMAN
θ value	8.99809 (rank : 335)	NC score	0.000106 (rank : 457)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

BCLF1_MOUSE
θ value	8.99809 (rank : 336)	NC score	0.035495 (rank : 359)
Query Neighborhood Hits	357	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

CCD41_MOUSE
θ value	8.99809 (rank : 337)	NC score	0.060237 (rank : 171)
Query Neighborhood Hits	357	Target Neighborhood Hits	1399	Shared Neighborhood Hits	172
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DCAK3_MOUSE
θ value	8.99809 (rank : 338)	NC score	-0.002883 (rank : 461)
Query Neighborhood Hits	357	Target Neighborhood Hits	922	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

DHX36_MOUSE
θ value	8.99809 (rank : 339)	NC score	0.024683 (rank : 390)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DZIP1_HUMAN
θ value	8.99809 (rank : 340)	NC score	0.032544 (rank : 366)
Query Neighborhood Hits	357	Target Neighborhood Hits	675	Shared Neighborhood Hits	92
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

DZIP3_MOUSE
θ value	8.99809 (rank : 341)	NC score	0.023441 (rank : 394)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

GNAS1_MOUSE
θ value	8.99809 (rank : 342)	NC score	0.000217 (rank : 456)
Query Neighborhood Hits	357	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

JHD2C_HUMAN
θ value	8.99809 (rank : 343)	NC score	0.011665 (rank : 438)
Query Neighborhood Hits	357	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

NFM_MOUSE
θ value	8.99809 (rank : 344)	NC score	0.040350 (rank : 346)
Query Neighborhood Hits	357	Target Neighborhood Hits	1159	Shared Neighborhood Hits	189
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NMDE1_HUMAN
θ value	8.99809 (rank : 345)	NC score	-0.000008 (rank : 459)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NOL3_HUMAN
θ value	8.99809 (rank : 346)	NC score	0.011785 (rank : 437)
Query Neighborhood Hits	357	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

PABP1_HUMAN
θ value	8.99809 (rank : 347)	NC score	0.002314 (rank : 455)
Query Neighborhood Hits	357	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PSMD2_MOUSE
θ value	8.99809 (rank : 348)	NC score	0.010115 (rank : 442)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

R51A1_MOUSE
θ value	8.99809 (rank : 349)	NC score	0.020075 (rank : 406)
Query Neighborhood Hits	357	Target Neighborhood Hits	164	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RAI14_MOUSE
θ value	8.99809 (rank : 350)	NC score	0.040658 (rank : 344)
Query Neighborhood Hits	357	Target Neighborhood Hits	1505	Shared Neighborhood Hits	166
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

REST_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.055267 (rank : 232)
Query Neighborhood Hits	357	Target Neighborhood Hits	1506	Shared Neighborhood Hits	169
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ROCK2_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.021391 (rank : 400)
Query Neighborhood Hits	357	Target Neighborhood Hits	2073	Shared Neighborhood Hits	159
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SMAL1_HUMAN
θ value	8.99809 (rank : 353)	NC score	0.085080 (rank : 103)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

STIM2_MOUSE
θ value	8.99809 (rank : 354)	NC score	0.032045 (rank : 370)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	97
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

STK10_HUMAN
θ value	8.99809 (rank : 355)	NC score	0.016729 (rank : 418)
Query Neighborhood Hits	357	Target Neighborhood Hits	1921	Shared Neighborhood Hits	155
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRI17_MOUSE
θ value	8.99809 (rank : 356)	NC score	0.007498 (rank : 449)
Query Neighborhood Hits	357	Target Neighborhood Hits	620	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

ZN512_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.000005 (rank : 458)
Query Neighborhood Hits	357	Target Neighborhood Hits	444	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

ACINU_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.058234 (rank : 194)
Query Neighborhood Hits	357	Target Neighborhood Hits	828	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.055143 (rank : 236)
Query Neighborhood Hits	357	Target Neighborhood Hits	712	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ARI4A_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.051781 (rank : 283)
Query Neighborhood Hits	357	Target Neighborhood Hits	434	Shared Neighborhood Hits	126
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

AZI1_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.053142 (rank : 257)
Query Neighborhood Hits	357	Target Neighborhood Hits	1000	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.051369 (rank : 294)
Query Neighborhood Hits	357	Target Neighborhood Hits	990	Shared Neighborhood Hits	148
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BRE1A_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.058090 (rank : 197)
Query Neighborhood Hits	357	Target Neighborhood Hits	1071	Shared Neighborhood Hits	173
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.058278 (rank : 193)
Query Neighborhood Hits	357	Target Neighborhood Hits	1025	Shared Neighborhood Hits	164
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

C102B_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.052992 (rank : 264)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	113
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CAF1A_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.065222 (rank : 148)
Query Neighborhood Hits	357	Target Neighborhood Hits	750	Shared Neighborhood Hits	165
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.065560 (rank : 146)
Query Neighborhood Hits	357	Target Neighborhood Hits	736	Shared Neighborhood Hits	168
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.078523 (rank : 114)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	193
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CC026_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.158819 (rank : 89)
Query Neighborhood Hits	357	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

CC026_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.121867 (rank : 91)
Query Neighborhood Hits	357	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CCAR1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.053425 (rank : 254)
Query Neighborhood Hits	357	Target Neighborhood Hits	444	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCAR1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.053079 (rank : 261)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CCD11_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.053783 (rank : 251)
Query Neighborhood Hits	357	Target Neighborhood Hits	822	Shared Neighborhood Hits	144
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD11_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.056078 (rank : 220)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD19_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.055294 (rank : 231)
Query Neighborhood Hits	357	Target Neighborhood Hits	639	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.051310 (rank : 296)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD39_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.052964 (rank : 266)
Query Neighborhood Hits	357	Target Neighborhood Hits	868	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.055459 (rank : 230)
Query Neighborhood Hits	357	Target Neighborhood Hits	1026	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD41_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.052210 (rank : 275)
Query Neighborhood Hits	357	Target Neighborhood Hits	1139	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD62_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.051855 (rank : 280)
Query Neighborhood Hits	357	Target Neighborhood Hits	631	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD96_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.053230 (rank : 256)
Query Neighborhood Hits	357	Target Neighborhood Hits	704	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCHCR_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.050424 (rank : 311)
Query Neighborhood Hits	357	Target Neighborhood Hits	932	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE152_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.055572 (rank : 227)
Query Neighborhood Hits	357	Target Neighborhood Hits	976	Shared Neighborhood Hits	140
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.051804 (rank : 281)
Query Neighborhood Hits	357	Target Neighborhood Hits	1553	Shared Neighborhood Hits	163
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPF_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.050687 (rank : 308)
Query Neighborhood Hits	357	Target Neighborhood Hits	1932	Shared Neighborhood Hits	173
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP63_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.051898 (rank : 278)
Query Neighborhood Hits	357	Target Neighborhood Hits	1005	Shared Neighborhood Hits	139
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CF010_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.053034 (rank : 262)
Query Neighborhood Hits	357	Target Neighborhood Hits	329	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CF152_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.050734 (rank : 307)
Query Neighborhood Hits	357	Target Neighborhood Hits	704	Shared Neighborhood Hits	128
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CIR_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.064481 (rank : 155)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	89
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

CIR_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.050974 (rank : 302)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CJ118_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.051110 (rank : 301)
Query Neighborhood Hits	357	Target Neighborhood Hits	937	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.054090 (rank : 248)
Query Neighborhood Hits	357	Target Neighborhood Hits	1132	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CN145_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.050326 (rank : 312)
Query Neighborhood Hits	357	Target Neighborhood Hits	916	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CP135_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.053087 (rank : 259)
Query Neighborhood Hits	357	Target Neighborhood Hits	1290	Shared Neighborhood Hits	149
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CRCM_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.051321 (rank : 295)
Query Neighborhood Hits	357	Target Neighborhood Hits	520	Shared Neighborhood Hits	109
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CROCC_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.051790 (rank : 282)
Query Neighborhood Hits	357	Target Neighborhood Hits	1409	Shared Neighborhood Hits	158
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROP_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.073708 (rank : 122)
Query Neighborhood Hits	357	Target Neighborhood Hits	402	Shared Neighborhood Hits	144
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

CROP_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.074040 (rank : 121)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	147
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.061101 (rank : 167)
Query Neighborhood Hits	357	Target Neighborhood Hits	902	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYLC1_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.079419 (rank : 112)
Query Neighborhood Hits	357	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.070289 (rank : 129)
Query Neighborhood Hits	357	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.054808 (rank : 243)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

GAS8_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.050013 (rank : 315)
Query Neighborhood Hits	357	Target Neighborhood Hits	819	Shared Neighborhood Hits	129
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOGA6_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.052250 (rank : 274)
Query Neighborhood Hits	357	Target Neighborhood Hits	1007	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.051706 (rank : 286)
Query Neighborhood Hits	357	Target Neighborhood Hits	944	Shared Neighborhood Hits	137
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GRAP1_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.055119 (rank : 237)
Query Neighborhood Hits	357	Target Neighborhood Hits	1234	Shared Neighborhood Hits	159
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HIRP3_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.068136 (rank : 137)
Query Neighborhood Hits	357	Target Neighborhood Hits	323	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HMMR_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.050180 (rank : 313)
Query Neighborhood Hits	357	Target Neighborhood Hits	1082	Shared Neighborhood Hits	139
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.055190 (rank : 233)
Query Neighborhood Hits	357	Target Neighborhood Hits	1178	Shared Neighborhood Hits	153
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

IF2P_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.079585 (rank : 111)
Query Neighborhood Hits	357	Target Neighborhood Hits	889	Shared Neighborhood Hits	194
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.069711 (rank : 132)
Query Neighborhood Hits	357	Target Neighborhood Hits	875	Shared Neighborhood Hits	174
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.068398 (rank : 135)
Query Neighborhood Hits	357	Target Neighborhood Hits	871	Shared Neighborhood Hits	179
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.051515 (rank : 291)
Query Neighborhood Hits	357	Target Neighborhood Hits	949	Shared Neighborhood Hits	133
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.050087 (rank : 314)
Query Neighborhood Hits	357	Target Neighborhood Hits	939	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.053023 (rank : 263)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	143
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.068154 (rank : 136)
Query Neighborhood Hits	357	Target Neighborhood Hits	978	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

INCE_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.070008 (rank : 131)
Query Neighborhood Hits	357	Target Neighborhood Hits	903	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.057650 (rank : 203)
Query Neighborhood Hits	357	Target Neighborhood Hits	636	Shared Neighborhood Hits	121
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

K0555_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.055496 (rank : 229)
Query Neighborhood Hits	357	Target Neighborhood Hits	880	Shared Neighborhood Hits	131
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

LRC45_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.051163 (rank : 300)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF2_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.051212 (rank : 297)
Query Neighborhood Hits	357	Target Neighborhood Hits	556	Shared Neighborhood Hits	105
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.059482 (rank : 179)
Query Neighborhood Hits	357	Target Neighborhood Hits	739	Shared Neighborhood Hits	134
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MAP1B_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.055497 (rank : 228)
Query Neighborhood Hits	357	Target Neighborhood Hits	977	Shared Neighborhood Hits	158
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP9_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.056022 (rank : 222)
Query Neighborhood Hits	357	Target Neighborhood Hits	518	Shared Neighborhood Hits	136
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MD1L1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.053253 (rank : 255)
Query Neighborhood Hits	357	Target Neighborhood Hits	893	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.052905 (rank : 267)
Query Neighborhood Hits	357	Target Neighborhood Hits	1001	Shared Neighborhood Hits	132
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MFAP1_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.051393 (rank : 293)
Query Neighborhood Hits	357	Target Neighborhood Hits	353	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

MY18B_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.057892 (rank : 198)
Query Neighborhood Hits	357	Target Neighborhood Hits	1299	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH14_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.052800 (rank : 269)
Query Neighborhood Hits	357	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH6_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.055020 (rank : 240)
Query Neighborhood Hits	357	Target Neighborhood Hits	1426	Shared Neighborhood Hits	159
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NOP14_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.051762 (rank : 284)
Query Neighborhood Hits	357	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSBP1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.082018 (rank : 107)
Query Neighborhood Hits	357	Target Neighborhood Hits	251	Shared Neighborhood Hits	96
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

OPTN_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.050895 (rank : 303)
Query Neighborhood Hits	357	Target Neighborhood Hits	1120	Shared Neighborhood Hits	153
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PININ_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.064195 (rank : 156)
Query Neighborhood Hits	357	Target Neighborhood Hits	753	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.067621 (rank : 139)
Query Neighborhood Hits	357	Target Neighborhood Hits	777	Shared Neighborhood Hits	162
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RAD50_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.054358 (rank : 245)
Query Neighborhood Hits	357	Target Neighborhood Hits	1317	Shared Neighborhood Hits	156
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.057221 (rank : 208)
Query Neighborhood Hits	357	Target Neighborhood Hits	1366	Shared Neighborhood Hits	157
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.051996 (rank : 277)
Query Neighborhood Hits	357	Target Neighborhood Hits	1433	Shared Neighborhood Hits	161
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.050746 (rank : 306)
Query Neighborhood Hits	357	Target Neighborhood Hits	1023	Shared Neighborhood Hits	148
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBM25_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.090477 (rank : 101)
Query Neighborhood Hits	357	Target Neighborhood Hits	682	Shared Neighborhood Hits	184
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

REN3B_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.068559 (rank : 134)
Query Neighborhood Hits	357	Target Neighborhood Hits	412	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

RENT2_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.064900 (rank : 151)
Query Neighborhood Hits	357	Target Neighborhood Hits	618	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RPGR1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.054819 (rank : 242)
Query Neighborhood Hits	357	Target Neighborhood Hits	713	Shared Neighborhood Hits	176
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SDCG8_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.053543 (rank : 253)
Query Neighborhood Hits	357	Target Neighborhood Hits	886	Shared Neighborhood Hits	130
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SFR11_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.083200 (rank : 106)
Query Neighborhood Hits	357	Target Neighborhood Hits	246	Shared Neighborhood Hits	91
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.095968 (rank : 98)
Query Neighborhood Hits	357	Target Neighborhood Hits	553	Shared Neighborhood Hits	173
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.088340 (rank : 102)
Query Neighborhood Hits	357	Target Neighborhood Hits	486	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SFR17_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.073602 (rank : 123)
Query Neighborhood Hits	357	Target Neighborhood Hits	325	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

SFRS4_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.052814 (rank : 268)
Query Neighborhood Hits	357	Target Neighborhood Hits	406	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

SKIV2_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.050793 (rank : 305)
Query Neighborhood Hits	357	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

SM1L2_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.051745 (rank : 285)
Query Neighborhood Hits	357	Target Neighborhood Hits	1019	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SM1L2_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.055182 (rank : 234)
Query Neighborhood Hits	357	Target Neighborhood Hits	918	Shared Neighborhood Hits	138
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMAL1_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.056794 (rank : 211)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMC2_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.058093 (rank : 196)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	174
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.051200 (rank : 298)
Query Neighborhood Hits	357	Target Neighborhood Hits	1131	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

T2_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.093083 (rank : 99)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	67
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

TAXB1_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.051592 (rank : 288)
Query Neighborhood Hits	357	Target Neighborhood Hits	829	Shared Neighborhood Hits	138
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

THOC2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.052308 (rank : 273)
Query Neighborhood Hits	357	Target Neighborhood Hits	337	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TMF1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.052010 (rank : 276)
Query Neighborhood Hits	357	Target Neighborhood Hits	987	Shared Neighborhood Hits	145
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPR_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.056269 (rank : 214)
Query Neighborhood Hits	357	Target Neighborhood Hits	1921	Shared Neighborhood Hits	183
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRDN_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.075454 (rank : 119)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	150
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.075328 (rank : 120)
Query Neighborhood Hits	357	Target Neighborhood Hits	1385	Shared Neighborhood Hits	201
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.053079 (rank : 260)
Query Neighborhood Hits	357	Target Neighborhood Hits	1587	Shared Neighborhood Hits	157
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

WDR60_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.051535 (rank : 290)
Query Neighborhood Hits	357	Target Neighborhood Hits	344	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

XE7_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.065128 (rank : 149)
Query Neighborhood Hits	357	Target Neighborhood Hits	738	Shared Neighborhood Hits	161
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

Hits sorted by NC score

DDX46_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	357	Target Neighborhood Hits	357	Shared Neighborhood Hits	357
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
NC score	0.996339 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	357	Target Neighborhood Hits	358	Shared Neighborhood Hits	309
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX17_MOUSE
NC score	0.965843 (rank : 3)	θ value	2.08291e-97 (rank : 5)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q501J6, Q6P5G1, Q8BIN2	Gene names	Ddx17
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17).

DDX17_HUMAN
NC score	0.965721 (rank : 4)	θ value	2.08291e-97 (rank : 4)
Query Neighborhood Hits	357	Target Neighborhood Hits	104	Shared Neighborhood Hits	88
SwissProt Accessions	Q92841, Q69YT1, Q6ICD6	Gene names	DDX17
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX17 (EC 3.6.1.-) (DEAD box protein 17) (RNA-dependent helicase p72) (DEAD box protein p72).

DDX43_HUMAN
NC score	0.964893 (rank : 5)	θ value	9.69798e-87 (rank : 7)
Query Neighborhood Hits	357	Target Neighborhood Hits	120	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NXZ2, Q6NXR1	Gene names	DDX43, HAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX43 (EC 3.6.1.-) (DEAD box protein 43) (DEAD box protein HAGE) (Helical antigen).

DDX5_MOUSE
NC score	0.964111 (rank : 6)	θ value	1.59483e-97 (rank : 3)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	Q61656	Gene names	Ddx5, Tnz2
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68) (DEAD box RNA helicase DEAD1) (mDEAD1).

DDX5_HUMAN
NC score	0.964038 (rank : 7)	θ value	4.64023e-97 (rank : 6)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	P17844, O75681	Gene names	DDX5, HELR, HLR1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.1.-) (DEAD box protein 5) (RNA helicase p68).

DDX23_HUMAN
NC score	0.961919 (rank : 8)	θ value	3.68522e-86 (rank : 8)
Query Neighborhood Hits	357	Target Neighborhood Hits	486	Shared Neighborhood Hits	227
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DDX53_HUMAN
NC score	0.958601 (rank : 9)	θ value	1.54831e-84 (rank : 9)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	84
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DDX4_MOUSE
NC score	0.958341 (rank : 10)	θ value	1.15091e-71 (rank : 16)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	92
SwissProt Accessions	Q61496, Q9D5X7	Gene names	Ddx4, Vasa
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog) (Mvh).

DDX41_HUMAN
NC score	0.957661 (rank : 11)	θ value	3.83135e-67 (rank : 17)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
NC score	0.957258 (rank : 12)	θ value	5.00389e-67 (rank : 18)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DDX4_HUMAN
NC score	0.957252 (rank : 13)	θ value	1.7756e-72 (rank : 15)
Query Neighborhood Hits	357	Target Neighborhood Hits	123	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NQI0, Q86VX0, Q9NT92, Q9NYB1	Gene names	DDX4, VASA
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX4 (EC 3.6.1.-) (DEAD box protein 4) (VASA homolog).

DDX3X_HUMAN
NC score	0.952283 (rank : 14)	θ value	1.40363e-77 (rank : 12)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	94
SwissProt Accessions	O00571, O15536	Gene names	DDX3X, DBX, DDX3
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (Helicase-like protein 2) (HLP2) (DEAD box, X isoform).

DDX3Y_MOUSE
NC score	0.952275 (rank : 15)	θ value	1.11217e-74 (rank : 14)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

DDX47_MOUSE
NC score	0.952065 (rank : 16)	θ value	2.25136e-59 (rank : 20)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9CWX9	Gene names	Ddx47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

DDX47_HUMAN
NC score	0.952009 (rank : 17)	θ value	2.65945e-60 (rank : 19)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H0S4, Q96GM0, Q96NV8	Gene names	DDX47
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX47 (EC 3.6.1.-) (DEAD box protein 47).

PL10_MOUSE
NC score	0.951982 (rank : 18)	θ value	1.07473e-77 (rank : 11)
Query Neighborhood Hits	357	Target Neighborhood Hits	120	Shared Neighborhood Hits	92
SwissProt Accessions	P16381	Gene names	D1Pas1, Pl10
Domain Architecture
Description	Putative ATP-dependent RNA helicase Pl10 (EC 3.6.1.-).

DDX3X_MOUSE
NC score	0.951832 (rank : 19)	θ value	6.96618e-77 (rank : 13)
Query Neighborhood Hits	357	Target Neighborhood Hits	117	Shared Neighborhood Hits	91
SwissProt Accessions	Q62167, O09060, O09143	Gene names	Ddx3x, D1Pas1-rs2, Ddx3, Dead3, Erh
Domain Architecture
Description	ATP-dependent RNA helicase DDX3X (EC 3.6.1.-) (DEAD box protein 3, X- chromosomal) (DEAD box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1Pas1-related sequence 2).

DDX52_HUMAN
NC score	0.951816 (rank : 20)	θ value	5.73848e-55 (rank : 25)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX52_MOUSE
NC score	0.951741 (rank : 21)	θ value	1.08223e-53 (rank : 26)
Query Neighborhood Hits	357	Target Neighborhood Hits	101	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K301, Q8BV29	Gene names	Ddx52, Rok1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DDX3Y_HUMAN
NC score	0.950983 (rank : 22)	θ value	6.30065e-78 (rank : 10)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	O15523, Q8IYV7	Gene names	DDX3Y, DBY
Domain Architecture
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal).

DDX49_MOUSE
NC score	0.949552 (rank : 23)	θ value	5.19021e-56 (rank : 24)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	94
SwissProt Accessions	Q4FZF3	Gene names	Ddx49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX49_HUMAN
NC score	0.947390 (rank : 24)	θ value	1.78386e-56 (rank : 22)
Query Neighborhood Hits	357	Target Neighborhood Hits	223	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

DDX6_HUMAN
NC score	0.945475 (rank : 25)	θ value	1.19655e-52 (rank : 27)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P26196	Gene names	DDX6, HLR2, RCK
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK).

DDX6_MOUSE
NC score	0.945235 (rank : 26)	θ value	1.19655e-52 (rank : 28)
Query Neighborhood Hits	357	Target Neighborhood Hits	98	Shared Neighborhood Hits	87
SwissProt Accessions	P54823	Gene names	Ddx6, Hlr2, Rck
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX6 (EC 3.6.1.-) (DEAD box protein 6) (ATP-dependent RNA helicase p54) (Oncogene RCK homolog).

DDX54_MOUSE
NC score	0.945099 (rank : 27)	θ value	6.55044e-59 (rank : 21)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K4L0	Gene names	Ddx54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54).

DDX27_MOUSE
NC score	0.943492 (rank : 28)	θ value	3.48949e-44 (rank : 44)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	114
SwissProt Accessions	Q921N6, Q8R0W3, Q8R1E2	Gene names	Ddx27
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX27_HUMAN
NC score	0.943078 (rank : 29)	θ value	6.35935e-46 (rank : 41)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	124
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

DDX54_HUMAN
NC score	0.942543 (rank : 30)	θ value	2.32979e-56 (rank : 23)
Query Neighborhood Hits	357	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

DDX48_HUMAN
NC score	0.939233 (rank : 31)	θ value	7.75577e-52 (rank : 29)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
NC score	0.939023 (rank : 32)	θ value	1.01294e-51 (rank : 30)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX28_MOUSE
NC score	0.937038 (rank : 33)	θ value	3.61106e-41 (rank : 50)
Query Neighborhood Hits	357	Target Neighborhood Hits	112	Shared Neighborhood Hits	94
SwissProt Accessions	Q9CWT6, Q3TQM0	Gene names	Ddx28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX50_MOUSE
NC score	0.936633 (rank : 34)	θ value	1.28137e-46 (rank : 38)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	106
SwissProt Accessions	Q99MJ9	Gene names	Ddx50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

DDX50_HUMAN
NC score	0.935501 (rank : 35)	θ value	2.18568e-46 (rank : 40)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BQ39, Q8WV76, Q9BWI8	Gene names	DDX50
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX50 (EC 3.6.1.-) (DEAD box protein 50) (Nucleolar protein Gu2) (Gu-beta).

IF4A1_HUMAN
NC score	0.934467 (rank : 36)	θ value	5.20228e-48 (rank : 31)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.934467 (rank : 37)	θ value	5.20228e-48 (rank : 32)
Query Neighborhood Hits	357	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.934132 (rank : 38)	θ value	2.58187e-47 (rank : 34)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.934132 (rank : 39)	θ value	2.58187e-47 (rank : 35)
Query Neighborhood Hits	357	Target Neighborhood Hits	102	Shared Neighborhood Hits	87
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX55_MOUSE
NC score	0.933773 (rank : 40)	θ value	3.85808e-43 (rank : 48)
Query Neighborhood Hits	357	Target Neighborhood Hits	111	Shared Neighborhood Hits	93
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.932918 (rank : 41)	θ value	1.01529e-43 (rank : 45)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX39_MOUSE
NC score	0.932837 (rank : 42)	θ value	1.51363e-47 (rank : 33)
Query Neighborhood Hits	357	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VDW0, Q3UJV4, Q8C2C2	Gene names	Ddx39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39).

DDX39_HUMAN
NC score	0.932764 (rank : 43)	θ value	2.18568e-46 (rank : 39)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	87
SwissProt Accessions	O00148, Q9BVP6, Q9H5W0	Gene names	DDX39
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX39 (EC 3.6.1.-) (DEAD box protein 39) (Nuclear RNA helicase URH49).

DDX21_HUMAN
NC score	0.931603 (rank : 44)	θ value	3.15612e-45 (rank : 42)
Query Neighborhood Hits	357	Target Neighborhood Hits	308	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX31_HUMAN
NC score	0.931398 (rank : 45)	θ value	6.15952e-41 (rank : 51)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	95
SwissProt Accessions	Q9H8H2, Q5K6N2, Q5K6N3, Q5K6N4, Q5VZJ4, Q5VZJ9, Q96E91, Q96NY2, Q96SX5, Q9H5K6	Gene names	DDX31
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX31 (EC 3.6.1.-) (DEAD box protein 31) (Helicain).

UAP56_HUMAN
NC score	0.930859 (rank : 46)	θ value	9.81109e-47 (rank : 36)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q13838, O43496, Q5RJ64, Q5RJ66, Q5ST94, Q5STB4, Q5STB5, Q5STB7, Q5STU4, Q5STU5, Q5STU6, Q5STU8, Q71V76	Gene names	BAT1, UAP56
Domain Architecture
Description	Spliceosome RNA helicase BAT1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (HLA-B-associated transcript-1).

DDX10_HUMAN
NC score	0.930761 (rank : 47)	θ value	1.73182e-43 (rank : 46)
Query Neighborhood Hits	357	Target Neighborhood Hits	210	Shared Neighborhood Hits	132
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

UAP56_MOUSE
NC score	0.930677 (rank : 48)	θ value	9.81109e-47 (rank : 37)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z1N5, Q8HW97	Gene names	Bat1, Bat1a, Uap56
Domain Architecture	No domain graphic available
Description	Spliceosome RNA helicase Bat1 (EC 3.6.1.-) (DEAD box protein UAP56) (56 kDa U2AF65-associated protein) (HLA-B-associated transcript 1).

DDX18_MOUSE
NC score	0.930548 (rank : 49)	θ value	2.50074e-42 (rank : 49)
Query Neighborhood Hits	357	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K363, Q3MIB0, Q8BVZ2, Q9D2E0	Gene names	Ddx18
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18).

DDX28_HUMAN
NC score	0.930468 (rank : 50)	θ value	4.568e-36 (rank : 55)
Query Neighborhood Hits	357	Target Neighborhood Hits	103	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NUL7	Gene names	DDX28, MDDX28
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX28 (EC 3.6.1.-) (Mitochondrial DEAD box protein 28).

DDX18_HUMAN
NC score	0.930456 (rank : 51)	θ value	1.3722e-40 (rank : 52)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NVP1, Q6IAU4, Q92732, Q9BQB7	Gene names	DDX18
Domain Architecture
Description	ATP-dependent RNA helicase DDX18 (EC 3.6.1.-) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb).

DDX10_MOUSE
NC score	0.927648 (rank : 52)	θ value	1.73182e-43 (rank : 47)
Query Neighborhood Hits	357	Target Neighborhood Hits	233	Shared Neighborhood Hits	132
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DDX21_MOUSE
NC score	0.924408 (rank : 53)	θ value	4.122e-45 (rank : 43)
Query Neighborhood Hits	357	Target Neighborhood Hits	350	Shared Neighborhood Hits	135
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DDX56_MOUSE
NC score	0.922316 (rank : 54)	θ value	1.24399e-33 (rank : 56)
Query Neighborhood Hits	357	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D0R4	Gene names	Ddx56, D11Ertd619e, Noh61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase).

DDX56_HUMAN
NC score	0.921742 (rank : 55)	θ value	1.79631e-32 (rank : 57)
Query Neighborhood Hits	357	Target Neighborhood Hits	77	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

DDX20_HUMAN
NC score	0.911404 (rank : 56)	θ value	8.3442e-30 (rank : 62)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UHI6, Q96F72, Q9NVM3, Q9UF59, Q9UIY0, Q9Y659	Gene names	DDX20, DP103, GEMIN3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3).

DDX24_MOUSE
NC score	0.909471 (rank : 57)	θ value	4.57862e-28 (rank : 65)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESV0, Q61119	Gene names	Ddx24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DDX25_HUMAN
NC score	0.909038 (rank : 58)	θ value	2.05049e-36 (rank : 54)
Query Neighborhood Hits	357	Target Neighborhood Hits	93	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UHL0, Q86W81, Q8IYP1	Gene names	DDX25, GRTH
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX51_MOUSE
NC score	0.908991 (rank : 59)	θ value	3.74554e-30 (rank : 61)
Query Neighborhood Hits	357	Target Neighborhood Hits	130	Shared Neighborhood Hits	92
SwissProt Accessions	Q6P9R1, Q3U7M2	Gene names	Ddx51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX25_MOUSE
NC score	0.908835 (rank : 60)	θ value	4.88048e-38 (rank : 53)
Query Neighborhood Hits	357	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

DDX20_MOUSE
NC score	0.908426 (rank : 61)	θ value	1.85889e-29 (rank : 63)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

DDX24_HUMAN
NC score	0.907071 (rank : 62)	θ value	5.97985e-28 (rank : 66)
Query Neighborhood Hits	357	Target Neighborhood Hits	190	Shared Neighborhood Hits	100
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

DD19A_HUMAN
NC score	0.903042 (rank : 63)	θ value	2.19584e-30 (rank : 60)
Query Neighborhood Hits	357	Target Neighborhood Hits	107	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NUU7, Q53FM0	Gene names	DDX19A, DDX19L
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DDX19-like protein).

DD19B_HUMAN
NC score	0.902557 (rank : 64)	θ value	1.28732e-30 (rank : 59)
Query Neighborhood Hits	357	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UMR2, Q6FIB7, Q6IAE0	Gene names	DDX19B, DBP5, DDX19
Domain Architecture
Description	ATP-dependent RNA helicase DDX19B (EC 3.6.1.-) (DEAD box protein 19B) (DEAD box RNA helicase DEAD5).

DD19A_MOUSE
NC score	0.902344 (rank : 65)	θ value	1.28732e-30 (rank : 58)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	85
SwissProt Accessions	Q61655, Q921R0	Gene names	Ddx19a, Ddx19, Eif4a-rs1
Domain Architecture
Description	ATP-dependent RNA helicase DDX19A (EC 3.6.1.-) (DEAD box protein 19A) (DEAD box RNA helicase DEAD5) (mDEAD5) (Eukaryotic translation initiation factor 4A-related sequence 1).

DDX51_HUMAN
NC score	0.895560 (rank : 66)	θ value	4.14116e-29 (rank : 64)
Query Neighborhood Hits	357	Target Neighborhood Hits	332	Shared Neighborhood Hits	109
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DDX1_MOUSE
NC score	0.872773 (rank : 67)	θ value	4.43474e-23 (rank : 67)
Query Neighborhood Hits	357	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q91VR5, Q3TU41	Gene names	Ddx1
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1).

DDX1_HUMAN
NC score	0.871139 (rank : 68)	θ value	4.9032e-22 (rank : 68)
Query Neighborhood Hits	357	Target Neighborhood Hits	110	Shared Neighborhood Hits	83
SwissProt Accessions	Q92499	Gene names	DDX1
Domain Architecture
Description	ATP-dependent RNA helicase DDX1 (EC 3.6.1.-) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB).

RECQ4_HUMAN
NC score	0.596210 (rank : 69)	θ value	1.133e-10 (rank : 70)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	92
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

RECQ4_MOUSE
NC score	0.588694 (rank : 70)	θ value	4.16044e-13 (rank : 69)
Query Neighborhood Hits	357	Target Neighborhood Hits	206	Shared Neighborhood Hits	90
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

BLM_MOUSE
NC score	0.541074 (rank : 71)	θ value	2.13673e-09 (rank : 73)
Query Neighborhood Hits	357	Target Neighborhood Hits	108	Shared Neighborhood Hits	77
SwissProt Accessions	O88700, O88198	Gene names	Blm
Domain Architecture
Description	Bloom syndrome protein homolog (EC 3.6.1.-) (mBLM).

BLM_HUMAN
NC score	0.528471 (rank : 72)	θ value	4.76016e-09 (rank : 74)
Query Neighborhood Hits	357	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

WRN_HUMAN
NC score	0.518026 (rank : 73)	θ value	1.63604e-09 (rank : 72)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	92
SwissProt Accessions	Q14191	Gene names	WRN, RECQ3, RECQL2
Domain Architecture
Description	Werner syndrome ATP-dependent helicase (EC 3.6.1.-).

RECQ5_HUMAN
NC score	0.511346 (rank : 74)	θ value	4.0297e-08 (rank : 75)
Query Neighborhood Hits	357	Target Neighborhood Hits	390	Shared Neighborhood Hits	91
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

WRN_MOUSE
NC score	0.497361 (rank : 75)	θ value	5.62301e-10 (rank : 71)
Query Neighborhood Hits	357	Target Neighborhood Hits	295	Shared Neighborhood Hits	125
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RECQ1_HUMAN
NC score	0.477536 (rank : 76)	θ value	1.29631e-06 (rank : 76)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P46063	Gene names	RECQL, RECQL1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

RECQ1_MOUSE
NC score	0.475982 (rank : 77)	θ value	5.44631e-05 (rank : 83)
Query Neighborhood Hits	357	Target Neighborhood Hits	95	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z129, Q9Z128	Gene names	Recql, Recql1
Domain Architecture
Description	ATP-dependent DNA helicase Q1 (EC 3.6.1.-) (DNA-dependent ATPase Q1).

FANCM_HUMAN
NC score	0.427712 (rank : 78)	θ value	0.0148317 (rank : 115)
Query Neighborhood Hits	357	Target Neighborhood Hits	210	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
NC score	0.425517 (rank : 79)	θ value	0.0252991 (rank : 118)
Query Neighborhood Hits	357	Target Neighborhood Hits	177	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

DICER_MOUSE
NC score	0.411599 (rank : 80)	θ value	0.00175202 (rank : 96)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	85
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

DICER_HUMAN
NC score	0.411478 (rank : 81)	θ value	0.00298849 (rank : 99)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UPY3, O95943, Q9UQ02	Gene names	DICER1, DICER, HERNA, KIAA0928
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Helicase with RNase motif) (Helicase-MOI).

LGP2_MOUSE
NC score	0.372156 (rank : 82)	θ value	3.19293e-05 (rank : 81)
Query Neighborhood Hits	357	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q99J87, Q9D1X4	Gene names	Lgp2, D11lgp2e
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2).

IFIH1_HUMAN
NC score	0.359060 (rank : 83)	θ value	0.00665767 (rank : 104)
Query Neighborhood Hits	357	Target Neighborhood Hits	96	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYX4, Q6DC96, Q86X56, Q96MX8, Q9H3G6	Gene names	IFIH1, MDA5, RH116
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon-induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5) (RNA helicase-DEAD box protein 116) (Murabutide-down- regulated protein).

LGP2_HUMAN
NC score	0.358501 (rank : 84)	θ value	3.77169e-06 (rank : 77)
Query Neighborhood Hits	357	Target Neighborhood Hits	94	Shared Neighborhood Hits	75
SwissProt Accessions	Q96C10, Q9HAM6	Gene names	LGP2, D11LGP2E
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent helicase LGP2 (EC 3.6.1.-) (Protein D11Lgp2 homolog).

IFIH1_MOUSE
NC score	0.345837 (rank : 85)	θ value	0.00298849 (rank : 100)
Query Neighborhood Hits	357	Target Neighborhood Hits	126	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

DDX58_MOUSE
NC score	0.247506 (rank : 86)	θ value	0.00298849 (rank : 98)
Query Neighborhood Hits	357	Target Neighborhood Hits	99	Shared Neighborhood Hits	68
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

DDX58_HUMAN
NC score	0.218458 (rank : 87)	θ value	0.000602161 (rank : 91)
Query Neighborhood Hits	357	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

U520_HUMAN
NC score	0.178506 (rank : 88)	θ value	0.000121331 (rank : 87)
Query Neighborhood Hits	357	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

CC026_HUMAN
NC score	0.158819 (rank : 89)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	357	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BQ75	Gene names	C3orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26.

HELC1_HUMAN
NC score	0.144729 (rank : 90)	θ value	0.00869519 (rank : 106)
Query Neighborhood Hits	357	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

CC026_MOUSE
NC score	0.121867 (rank : 91)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	357	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZT6, Q9CY77	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf26 homolog.

CCD55_HUMAN
NC score	0.116809 (rank : 92)	θ value	8.40245e-06 (rank : 79)
Query Neighborhood Hits	357	Target Neighborhood Hits	513	Shared Neighborhood Hits	133
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ZC313_HUMAN
NC score	0.116708 (rank : 93)	θ value	0.0330416 (rank : 124)
Query Neighborhood Hits	357	Target Neighborhood Hits	772	Shared Neighborhood Hits	178
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

NIPBL_HUMAN
NC score	0.101047 (rank : 94)	θ value	4.92598e-06 (rank : 78)
Query Neighborhood Hits	357	Target Neighborhood Hits	1311	Shared Neighborhood Hits	167
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CCD55_MOUSE
NC score	0.099820 (rank : 95)	θ value	0.0961366 (rank : 139)
Query Neighborhood Hits	357	Target Neighborhood Hits	519	Shared Neighborhood Hits	132
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

NPBL_MOUSE
NC score	0.098033 (rank : 96)	θ value	2.44474e-05 (rank : 80)
Query Neighborhood Hits	357	Target Neighborhood Hits	1041	Shared Neighborhood Hits	135
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SFRIP_HUMAN
NC score	0.097126 (rank : 97)	θ value	0.000602161 (rank : 93)
Query Neighborhood Hits	357	Target Neighborhood Hits	530	Shared Neighborhood Hits	81
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFR12_HUMAN
NC score	0.095968 (rank : 98)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	357	Target Neighborhood Hits	553	Shared Neighborhood Hits	173
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

T2_MOUSE
NC score	0.093083 (rank : 99)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	357	Target Neighborhood Hits	140	Shared Neighborhood Hits	67
SwissProt Accessions	Q06666	Gene names	Srst, T2
Domain Architecture	No domain graphic available
Description	Octapeptide-repeat protein T2.

RBBP6_HUMAN
NC score	0.091183 (rank : 100)	θ value	7.1131e-05 (rank : 84)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBM25_HUMAN
NC score	0.090477 (rank : 101)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	357	Target Neighborhood Hits	682	Shared Neighborhood Hits	184
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SFR12_MOUSE
NC score	0.088340 (rank : 102)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	357	Target Neighborhood Hits	486	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SMAL1_HUMAN
NC score	0.085080 (rank : 103)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	357	Target Neighborhood Hits	174	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

NOP14_HUMAN
NC score	0.083657 (rank : 104)	θ value	0.0113563 (rank : 112)
Query Neighborhood Hits	357	Target Neighborhood Hits	573	Shared Neighborhood Hits	131
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

LEO1_HUMAN
NC score	0.083405 (rank : 105)	θ value	0.000158464 (rank : 88)
Query Neighborhood Hits	357	Target Neighborhood Hits	958	Shared Neighborhood Hits	109
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SFR11_HUMAN
NC score	0.083200 (rank : 106)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	357	Target Neighborhood Hits	246	Shared Neighborhood Hits	91
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

NSBP1_HUMAN
NC score	0.082018 (rank : 107)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	357	Target Neighborhood Hits	251	Shared Neighborhood Hits	96
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

RBBP6_MOUSE
NC score	0.081227 (rank : 108)	θ value	0.0252991 (rank : 120)
Query Neighborhood Hits	357	Target Neighborhood Hits	1014	Shared Neighborhood Hits	136
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RRBP1_MOUSE
NC score	0.080980 (rank : 109)	θ value	0.00102713 (rank : 95)
Query Neighborhood Hits	357	Target Neighborhood Hits	1650	Shared Neighborhood Hits	193
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

LEO1_MOUSE
NC score	0.080279 (rank : 110)	θ value	0.0113563 (rank : 111)
Query Neighborhood Hits	357	Target Neighborhood Hits	946	Shared Neighborhood Hits	109
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

IF2P_HUMAN
NC score	0.079585 (rank : 111)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	357	Target Neighborhood Hits	889	Shared Neighborhood Hits	194
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CYLC1_HUMAN
NC score	0.079419 (rank : 112)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	357	Target Neighborhood Hits	408	Shared Neighborhood Hits	127
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

FILA_HUMAN
NC score	0.078961 (rank : 113)	θ value	0.00665767 (rank : 103)
Query Neighborhood Hits	357	Target Neighborhood Hits	685	Shared Neighborhood Hits	70
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CALD1_HUMAN
NC score	0.078523 (rank : 114)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	193
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

TXND2_MOUSE
NC score	0.077318 (rank : 115)	θ value	0.000121331 (rank : 86)
Query Neighborhood Hits	357	Target Neighborhood Hits	828	Shared Neighborhood Hits	126
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CI039_HUMAN
NC score	0.076540 (rank : 116)	θ value	9.29e-05 (rank : 85)
Query Neighborhood Hits	357	Target Neighborhood Hits	1171	Shared Neighborhood Hits	152
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

PPIG_HUMAN
NC score	0.076199 (rank : 117)	θ value	0.00869519 (rank : 109)
Query Neighborhood Hits	357	Target Neighborhood Hits	670	Shared Neighborhood Hits	162
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RRBP1_HUMAN
NC score	0.076077 (rank : 118)	θ value	0.00298849 (rank : 101)
Query Neighborhood Hits	357	Target Neighborhood Hits	1306	Shared Neighborhood Hits	178
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

TRDN_HUMAN
NC score	0.075454 (rank : 119)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	150
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
NC score	0.075328 (rank : 120)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	357	Target Neighborhood Hits	1385	Shared Neighborhood Hits	201
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CROP_MOUSE
NC score	0.074040 (rank : 121)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	147
SwissProt Accessions	Q5SUF2, Q3U9D5, Q8BUJ5, Q921Z3, Q9CRS7, Q9CTY4	Gene names	Crop
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein.

CROP_HUMAN
NC score	0.073708 (rank : 122)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	357	Target Neighborhood Hits	402	Shared Neighborhood Hits	144
SwissProt Accessions	O95232, Q6PHR9, Q9NUY0, Q9P2S7	Gene names	CROP, CREAP1, O48
Domain Architecture	No domain graphic available
Description	Cisplatin resistance-associated overexpressed protein (cAMP regulatory element-associated protein 1) (CRE-associated protein 1) (CREAP-1) (Luc7A) (Okadaic acid-inducible phosphoprotein OA48-18).

SFR17_HUMAN
NC score	0.073602 (rank : 123)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	357	Target Neighborhood Hits	325	Shared Neighborhood Hits	108
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

NASP_HUMAN
NC score	0.071760 (rank : 124)	θ value	0.00509761 (rank : 102)
Query Neighborhood Hits	357	Target Neighborhood Hits	709	Shared Neighborhood Hits	121
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

RBM15_HUMAN
NC score	0.071432 (rank : 125)	θ value	0.000602161 (rank : 92)
Query Neighborhood Hits	357	Target Neighborhood Hits	309	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

MPP8_HUMAN
NC score	0.071079 (rank : 126)	θ value	0.000158464 (rank : 89)
Query Neighborhood Hits	357	Target Neighborhood Hits	948	Shared Neighborhood Hits	154
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CK5P2_HUMAN
NC score	0.070825 (rank : 127)	θ value	0.0252991 (rank : 117)
Query Neighborhood Hits	357	Target Neighborhood Hits	1433	Shared Neighborhood Hits	181
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CT2NL_HUMAN
NC score	0.070418 (rank : 128)	θ value	0.163984 (rank : 161)
Query Neighborhood Hits	357	Target Neighborhood Hits	1059	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CYLC2_HUMAN
NC score	0.070289 (rank : 129)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	357	Target Neighborhood Hits	223	Shared Neighborhood Hits	72
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

MAP1A_HUMAN
NC score	0.070107 (rank : 130)	θ value	0.0252991 (rank : 119)
Query Neighborhood Hits	357	Target Neighborhood Hits	1626	Shared Neighborhood Hits	191
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

INCE_MOUSE
NC score	0.070008 (rank : 131)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	357	Target Neighborhood Hits	903	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

IF3A_HUMAN
NC score	0.069711 (rank : 132)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	357	Target Neighborhood Hits	875	Shared Neighborhood Hits	174
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

ATRX_HUMAN
NC score	0.069596 (rank : 133)	θ value	0.0148317 (rank : 113)
Query Neighborhood Hits	357	Target Neighborhood Hits	842	Shared Neighborhood Hits	179
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

REN3B_HUMAN
NC score	0.068559 (rank : 134)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	357	Target Neighborhood Hits	412	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BZI7, Q9H1J0	Gene names	UPF3B, RENT3B, UPF3X
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X).

IF3A_MOUSE
NC score	0.068398 (rank : 135)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	357	Target Neighborhood Hits	871	Shared Neighborhood Hits	179
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

INCE_HUMAN
NC score	0.068154 (rank : 136)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	357	Target Neighborhood Hits	978	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

HIRP3_HUMAN
NC score	0.068136 (rank : 137)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	357	Target Neighborhood Hits	323	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

DMP1_HUMAN
NC score	0.067719 (rank : 138)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	357	Target Neighborhood Hits	491	Shared Neighborhood Hits	75
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PININ_MOUSE
NC score	0.067621 (rank : 139)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	357	Target Neighborhood Hits	777	Shared Neighborhood Hits	162
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

TARA_MOUSE
NC score	0.067180 (rank : 140)	θ value	0.00665767 (rank : 105)
Query Neighborhood Hits	357	Target Neighborhood Hits	1133	Shared Neighborhood Hits	145
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LUZP1_MOUSE
NC score	0.067155 (rank : 141)	θ value	0.125558 (rank : 149)
Query Neighborhood Hits	357	Target Neighborhood Hits	940	Shared Neighborhood Hits	157
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MY18A_MOUSE
NC score	0.066782 (rank : 142)	θ value	0.125558 (rank : 151)
Query Neighborhood Hits	357	Target Neighborhood Hits	1989	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CK5P2_MOUSE
NC score	0.066708 (rank : 143)	θ value	1.81305 (rank : 231)
Query Neighborhood Hits	357	Target Neighborhood Hits	1151	Shared Neighborhood Hits	156
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

GOGA4_HUMAN
NC score	0.066505 (rank : 144)	θ value	0.0563607 (rank : 130)
Query Neighborhood Hits	357	Target Neighborhood Hits	2034	Shared Neighborhood Hits	195
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LRRF2_HUMAN
NC score	0.066337 (rank : 145)	θ value	0.000786445 (rank : 94)
Query Neighborhood Hits	357	Target Neighborhood Hits	791	Shared Neighborhood Hits	113
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

CAF1A_MOUSE
NC score	0.065560 (rank : 146)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	357	Target Neighborhood Hits	736	Shared Neighborhood Hits	168
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CF060_HUMAN
NC score	0.065504 (rank : 147)	θ value	0.0431538 (rank : 125)
Query Neighborhood Hits	357	Target Neighborhood Hits	1270	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CAF1A_HUMAN
NC score	0.065222 (rank : 148)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	357	Target Neighborhood Hits	750	Shared Neighborhood Hits	165
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

XE7_HUMAN
NC score	0.065128 (rank : 149)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	357	Target Neighborhood Hits	738	Shared Neighborhood Hits	161
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

MY18A_HUMAN
NC score	0.064961 (rank : 150)	θ value	0.125558 (rank : 150)
Query Neighborhood Hits	357	Target Neighborhood Hits	1929	Shared Neighborhood Hits	196
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RENT2_HUMAN
NC score	0.064900 (rank : 151)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	357	Target Neighborhood Hits	618	Shared Neighborhood Hits	166
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

GOGB1_HUMAN
NC score	0.064897 (rank : 152)	θ value	0.0330416 (rank : 121)
Query Neighborhood Hits	357	Target Neighborhood Hits	2297	Shared Neighborhood Hits	194
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TCRG1_MOUSE
NC score	0.064763 (rank : 153)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	357	Target Neighborhood Hits	947	Shared Neighborhood Hits	147
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TCRG1_HUMAN
NC score	0.064589 (rank : 154)	θ value	0.279714 (rank : 173)
Query Neighborhood Hits	357	Target Neighborhood Hits	929	Shared Neighborhood Hits	148
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

CIR_HUMAN
NC score	0.064481 (rank : 155)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	89
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

PININ_HUMAN
NC score	0.064195 (rank : 156)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	357	Target Neighborhood Hits	753	Shared Neighborhood Hits	161
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SYCP1_MOUSE
NC score	0.063963 (rank : 157)	θ value	0.21417 (rank : 170)
Query Neighborhood Hits	357	Target Neighborhood Hits	1456	Shared Neighborhood Hits	169
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CI093_HUMAN
NC score	0.063388 (rank : 158)	θ value	1.06291 (rank : 208)
Query Neighborhood Hits	357	Target Neighborhood Hits	1088	Shared Neighborhood Hits	144
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

SMC3_MOUSE
NC score	0.063056 (rank : 159)	θ value	0.0563607 (rank : 133)
Query Neighborhood Hits	357	Target Neighborhood Hits	1187	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.063043 (rank : 160)	θ value	0.0563607 (rank : 132)
Query Neighborhood Hits	357	Target Neighborhood Hits	1186	Shared Neighborhood Hits	157
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

FLIP1_HUMAN
NC score	0.062495 (rank : 161)	θ value	0.47712 (rank : 178)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	168
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

NSBP1_MOUSE
NC score	0.062018 (rank : 162)	θ value	0.125558 (rank : 153)
Query Neighborhood Hits	357	Target Neighborhood Hits	681	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

MYH9_MOUSE
NC score	0.061994 (rank : 163)	θ value	0.21417 (rank : 167)
Query Neighborhood Hits	357	Target Neighborhood Hits	1829	Shared Neighborhood Hits	183
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TR150_HUMAN
NC score	0.061800 (rank : 164)	θ value	0.125558 (rank : 156)
Query Neighborhood Hits	357	Target Neighborhood Hits	313	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

SYCP1_HUMAN
NC score	0.061632 (rank : 165)	θ value	1.06291 (rank : 213)
Query Neighborhood Hits	357	Target Neighborhood Hits	1313	Shared Neighborhood Hits	160
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CING_MOUSE
NC score	0.061372 (rank : 166)	θ value	0.62314 (rank : 188)
Query Neighborhood Hits	357	Target Neighborhood Hits	1432	Shared Neighborhood Hits	162
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CT2NL_MOUSE
NC score	0.061101 (rank : 167)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	357	Target Neighborhood Hits	902	Shared Neighborhood Hits	139
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MYH3_HUMAN
NC score	0.061023 (rank : 168)	θ value	0.125558 (rank : 152)
Query Neighborhood Hits	357	Target Neighborhood Hits	1660	Shared Neighborhood Hits	170
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH9_HUMAN
NC score	0.060568 (rank : 169)	θ value	0.47712 (rank : 182)
Query Neighborhood Hits	357	Target Neighborhood Hits	1762	Shared Neighborhood Hits	182
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH8_MOUSE
NC score	0.060412 (rank : 170)	θ value	0.00869519 (rank : 108)
Query Neighborhood Hits	357	Target Neighborhood Hits	1600	Shared Neighborhood Hits	168
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CCD41_MOUSE
NC score	0.060237 (rank : 171)	θ value	8.99809 (rank : 337)
Query Neighborhood Hits	357	Target Neighborhood Hits	1399	Shared Neighborhood Hits	172
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MYH8_HUMAN
NC score	0.060221 (rank : 172)	θ value	1.38821 (rank : 221)
Query Neighborhood Hits	357	Target Neighborhood Hits	1610	Shared Neighborhood Hits	174
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CCD46_MOUSE
NC score	0.060015 (rank : 173)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	170
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

KTN1_MOUSE
NC score	0.059937 (rank : 174)	θ value	3.0926 (rank : 253)
Query Neighborhood Hits	357	Target Neighborhood Hits	1324	Shared Neighborhood Hits	164
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

GOGA4_MOUSE
NC score	0.059816 (rank : 175)	θ value	1.81305 (rank : 233)
Query Neighborhood Hits	357	Target Neighborhood Hits	1939	Shared Neighborhood Hits	194
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH4_MOUSE
NC score	0.059798 (rank : 176)	θ value	0.00869519 (rank : 107)
Query Neighborhood Hits	357	Target Neighborhood Hits	1476	Shared Neighborhood Hits	159
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NUF2_HUMAN
NC score	0.059796 (rank : 177)	θ value	0.0961366 (rank : 143)
Query Neighborhood Hits	357	Target Neighborhood Hits	661	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

FLIP1_MOUSE
NC score	0.059688 (rank : 178)	θ value	3.0926 (rank : 250)
Query Neighborhood Hits	357	Target Neighborhood Hits	1176	Shared Neighborhood Hits	151
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LUZP1_HUMAN
NC score	0.059482 (rank : 179)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	357	Target Neighborhood Hits	739	Shared Neighborhood Hits	134
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYH4_HUMAN
NC score	0.059379 (rank : 180)	θ value	0.0563607 (rank : 131)
Query Neighborhood Hits	357	Target Neighborhood Hits	1377	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH11_MOUSE
NC score	0.059232 (rank : 181)	θ value	0.62314 (rank : 191)
Query Neighborhood Hits	357	Target Neighborhood Hits	1777	Shared Neighborhood Hits	185
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CCD46_HUMAN
NC score	0.059153 (rank : 182)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	357	Target Neighborhood Hits	1430	Shared Neighborhood Hits	153
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MYH1_HUMAN
NC score	0.059124 (rank : 183)	θ value	1.38821 (rank : 217)
Query Neighborhood Hits	357	Target Neighborhood Hits	1478	Shared Neighborhood Hits	163
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

TR150_MOUSE
NC score	0.059064 (rank : 184)	θ value	1.38821 (rank : 227)
Query Neighborhood Hits	357	Target Neighborhood Hits	468	Shared Neighborhood Hits	80
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

MYH1_MOUSE
NC score	0.058972 (rank : 185)	θ value	1.38821 (rank : 218)
Query Neighborhood Hits	357	Target Neighborhood Hits	1461	Shared Neighborhood Hits	161
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

CMGA_HUMAN
NC score	0.058702 (rank : 186)	θ value	0.0563607 (rank : 129)
Query Neighborhood Hits	357	Target Neighborhood Hits	238	Shared Neighborhood Hits	49
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

RB6I2_HUMAN
NC score	0.058694 (rank : 187)	θ value	3.0926 (rank : 257)
Query Neighborhood Hits	357	Target Neighborhood Hits	1584	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

TARA_HUMAN
NC score	0.058680 (rank : 188)	θ value	0.0736092 (rank : 138)
Query Neighborhood Hits	357	Target Neighborhood Hits	1626	Shared Neighborhood Hits	158
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RB15B_MOUSE
NC score	0.058373 (rank : 189)	θ value	0.00228821 (rank : 97)
Query Neighborhood Hits	357	Target Neighborhood Hits	284	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PHZ5, Q8C6G2	Gene names	Rbm15b
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

CING_HUMAN
NC score	0.058313 (rank : 190)	θ value	5.27518 (rank : 290)
Query Neighborhood Hits	357	Target Neighborhood Hits	1275	Shared Neighborhood Hits	150
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

PIBF1_HUMAN
NC score	0.058298 (rank : 191)	θ value	6.88961 (rank : 323)
Query Neighborhood Hits	357	Target Neighborhood Hits	1041	Shared Neighborhood Hits	142
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

MYH2_HUMAN
NC score	0.058290 (rank : 192)	θ value	1.38821 (rank : 219)
Query Neighborhood Hits	357	Target Neighborhood Hits	1491	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

BRE1A_MOUSE
NC score	0.058278 (rank : 193)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	357	Target Neighborhood Hits	1025	Shared Neighborhood Hits	164
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

ACINU_HUMAN
NC score	0.058234 (rank : 194)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	357	Target Neighborhood Hits	828	Shared Neighborhood Hits	162
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MYH13_HUMAN
NC score	0.058198 (rank : 195)	θ value	0.0330416 (rank : 123)
Query Neighborhood Hits	357	Target Neighborhood Hits	1504	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

SMC2_HUMAN
NC score	0.058093 (rank : 196)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	357	Target Neighborhood Hits	1405	Shared Neighborhood Hits	174
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

BRE1A_HUMAN
NC score	0.058090 (rank : 197)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	357	Target Neighborhood Hits	1071	Shared Neighborhood Hits	173
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

MY18B_HUMAN
NC score	0.057892 (rank : 198)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	357	Target Neighborhood Hits	1299	Shared Neighborhood Hits	155
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

SMC1A_MOUSE
NC score	0.057790 (rank : 199)	θ value	4.03905 (rank : 282)
Query Neighborhood Hits	357	Target Neighborhood Hits	1384	Shared Neighborhood Hits	171
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

IWS1_HUMAN
NC score	0.057770 (rank : 200)	θ value	3.0926 (rank : 252)
Query Neighborhood Hits	357	Target Neighborhood Hits	1241	Shared Neighborhood Hits	130
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH6_MOUSE
NC score	0.057724 (rank : 201)	θ value	1.38821 (rank : 220)
Query Neighborhood Hits	357	Target Neighborhood Hits	1501	Shared Neighborhood Hits	162
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

LIPA1_HUMAN
NC score	0.057694 (rank : 202)	θ value	0.0736092 (rank : 136)
Query Neighborhood Hits	357	Target Neighborhood Hits	1294	Shared Neighborhood Hits	157
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

INVO_HUMAN
NC score	0.057650 (rank : 203)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	357	Target Neighborhood Hits	636	Shared Neighborhood Hits	121
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

MYH11_HUMAN
NC score	0.057610 (rank : 204)	θ value	0.813845 (rank : 201)
Query Neighborhood Hits	357	Target Neighborhood Hits	1806	Shared Neighborhood Hits	184
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SMC1A_HUMAN
NC score	0.057490 (rank : 205)	θ value	4.03905 (rank : 281)
Query Neighborhood Hits	357	Target Neighborhood Hits	1346	Shared Neighborhood Hits	173
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MYH7_HUMAN
NC score	0.057394 (rank : 206)	θ value	4.03905 (rank : 275)
Query Neighborhood Hits	357	Target Neighborhood Hits	1559	Shared Neighborhood Hits	165
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

CP135_MOUSE
NC score	0.057225 (rank : 207)	θ value	0.279714 (rank : 171)
Query Neighborhood Hits	357	Target Neighborhood Hits	1278	Shared Neighborhood Hits	152
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

RAD50_MOUSE
NC score	0.057221 (rank : 208)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	357	Target Neighborhood Hits	1366	Shared Neighborhood Hits	157
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

MYH10_HUMAN
NC score	0.057025 (rank : 209)	θ value	0.47712 (rank : 181)
Query Neighborhood Hits	357	Target Neighborhood Hits	1620	Shared Neighborhood Hits	165
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.056896 (rank : 210)	θ value	0.365318 (rank : 176)
Query Neighborhood Hits	357	Target Neighborhood Hits	1612	Shared Neighborhood Hits	167
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SMAL1_MOUSE
NC score	0.056794 (rank : 211)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	357	Target Neighborhood Hits	157	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

STMN1_MOUSE
NC score	0.056749 (rank : 212)	θ value	0.163984 (rank : 166)
Query Neighborhood Hits	357	Target Neighborhood Hits	560	Shared Neighborhood Hits	110
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

YTDC1_HUMAN
NC score	0.056648 (rank : 213)	θ value	4.03905 (rank : 287)
Query Neighborhood Hits	357	Target Neighborhood Hits	458	Shared Neighborhood Hits	100
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TPR_HUMAN
NC score	0.056269 (rank : 214)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	357	Target Neighborhood Hits	1921	Shared Neighborhood Hits	183
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CN145_HUMAN
NC score	0.056139 (rank : 215)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	357	Target Neighborhood Hits	1196	Shared Neighborhood Hits	155
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GOGA5_MOUSE
NC score	0.056130 (rank : 216)	θ value	0.813845 (rank : 200)
Query Neighborhood Hits	357	Target Neighborhood Hits	1434	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

STMN1_HUMAN
NC score	0.056116 (rank : 217)	θ value	0.21417 (rank : 169)
Query Neighborhood Hits	357	Target Neighborhood Hits	554	Shared Neighborhood Hits	109
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

MYH14_MOUSE
NC score	0.056109 (rank : 218)	θ value	6.88961 (rank : 320)
Query Neighborhood Hits	357	Target Neighborhood Hits	1225	Shared Neighborhood Hits	156
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PHF20_MOUSE
NC score	0.056100 (rank : 219)	θ value	0.62314 (rank : 194)
Query Neighborhood Hits	357	Target Neighborhood Hits	513	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CCD11_MOUSE
NC score	0.056078 (rank : 220)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	118
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CROCC_MOUSE
NC score	0.056051 (rank : 221)	θ value	1.06291 (rank : 209)
Query Neighborhood Hits	357	Target Neighborhood Hits	1460	Shared Neighborhood Hits	168
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MAP9_HUMAN
NC score	0.056022 (rank : 222)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	357	Target Neighborhood Hits	518	Shared Neighborhood Hits	136
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SDCG8_HUMAN
NC score	0.056007 (rank : 223)	θ value	0.365318 (rank : 177)
Query Neighborhood Hits	357	Target Neighborhood Hits	1002	Shared Neighborhood Hits	141
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CCD21_HUMAN
NC score	0.055891 (rank : 224)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	357	Target Neighborhood Hits	1228	Shared Neighborhood Hits	152
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

IWS1_MOUSE
NC score	0.055844 (rank : 225)	θ value	0.0431538 (rank : 126)
Query Neighborhood Hits	357	Target Neighborhood Hits	1258	Shared Neighborhood Hits	105
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DESP_HUMAN
NC score	0.055588 (rank : 226)	θ value	4.03905 (rank : 266)
Query Neighborhood Hits	357	Target Neighborhood Hits	1470	Shared Neighborhood Hits	161
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CE152_HUMAN
NC score	0.055572 (rank : 227)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	357	Target Neighborhood Hits	976	Shared Neighborhood Hits	140
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

MAP1B_MOUSE
NC score	0.055497 (rank : 228)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	357	Target Neighborhood Hits	977	Shared Neighborhood Hits	158
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

K0555_HUMAN
NC score	0.055496 (rank : 229)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	357	Target Neighborhood Hits	880	Shared Neighborhood Hits	131
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

CCD39_MOUSE
NC score	0.055459 (rank : 230)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	357	Target Neighborhood Hits	1026	Shared Neighborhood Hits	145
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD19_HUMAN
NC score	0.055294 (rank : 231)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	357	Target Neighborhood Hits	639	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

REST_MOUSE
NC score	0.055267 (rank : 232)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	357	Target Neighborhood Hits	1506	Shared Neighborhood Hits	169
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

HMMR_MOUSE
NC score	0.055190 (rank : 233)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	357	Target Neighborhood Hits	1178	Shared Neighborhood Hits	153
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SM1L2_MOUSE
NC score	0.055182 (rank : 234)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	357	Target Neighborhood Hits	918	Shared Neighborhood Hits	138
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

GCC2_MOUSE
NC score	0.055147 (rank : 235)	θ value	5.27518 (rank : 297)
Query Neighborhood Hits	357	Target Neighborhood Hits	1619	Shared Neighborhood Hits	172
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

ACINU_MOUSE
NC score	0.055143 (rank : 236)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	357	Target Neighborhood Hits	712	Shared Neighborhood Hits	167
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

GRAP1_MOUSE
NC score	0.055119 (rank : 237)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	357	Target Neighborhood Hits	1234	Shared Neighborhood Hits	159
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

EEA1_MOUSE
NC score	0.055119 (rank : 238)	θ value	4.03905 (rank : 268)
Query Neighborhood Hits	357	Target Neighborhood Hits	1637	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

LIPA2_MOUSE
NC score	0.055104 (rank : 239)	θ value	0.47712 (rank : 179)
Query Neighborhood Hits	357	Target Neighborhood Hits	1282	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH6_HUMAN
NC score	0.055020 (rank : 240)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	357	Target Neighborhood Hits	1426	Shared Neighborhood Hits	159
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

KTN1_HUMAN
NC score	0.054938 (rank : 241)	θ value	4.03905 (rank : 274)
Query Neighborhood Hits	357	Target Neighborhood Hits	1197	Shared Neighborhood Hits	146
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RPGR1_MOUSE
NC score	0.054819 (rank : 242)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	357	Target Neighborhood Hits	713	Shared Neighborhood Hits	176
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

DMP1_MOUSE
NC score	0.054808 (rank : 243)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	357	Target Neighborhood Hits	498	Shared Neighborhood Hits	80
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

ERC2_MOUSE
NC score	0.054727 (rank : 244)	θ value	4.03905 (rank : 270)
Query Neighborhood Hits	357	Target Neighborhood Hits	1166	Shared Neighborhood Hits	148
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

RAD50_HUMAN
NC score	0.054358 (rank : 245)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	357	Target Neighborhood Hits	1317	Shared Neighborhood Hits	156
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

ERC2_HUMAN
NC score	0.054202 (rank : 246)	θ value	5.27518 (rank : 295)
Query Neighborhood Hits	357	Target Neighborhood Hits	1156	Shared Neighborhood Hits	146
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MCES_HUMAN
NC score	0.054126 (rank : 247)	θ value	0.0431538 (rank : 127)
Query Neighborhood Hits	357	Target Neighborhood Hits	134	Shared Neighborhood Hits	42
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

CJ118_MOUSE
NC score	0.054090 (rank : 248)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	357	Target Neighborhood Hits	1132	Shared Neighborhood Hits	151
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

GOGA5_HUMAN
NC score	0.053924 (rank : 249)	θ value	3.0926 (rank : 251)
Query Neighborhood Hits	357	Target Neighborhood Hits	1168	Shared Neighborhood Hits	145
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SAFB2_HUMAN
NC score	0.053914 (rank : 250)	θ value	3.0926 (rank : 260)
Query Neighborhood Hits	357	Target Neighborhood Hits	720	Shared Neighborhood Hits	152
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

CCD11_HUMAN
NC score	0.053783 (rank : 251)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	357	Target Neighborhood Hits	822	Shared Neighborhood Hits	144
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

REST_HUMAN
NC score	0.053594 (rank : 252)	θ value	6.88961 (rank : 326)
Query Neighborhood Hits	357	Target Neighborhood Hits	1605	Shared Neighborhood Hits	171
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SDCG8_MOUSE
NC score	0.053543 (rank : 253)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	357	Target Neighborhood Hits	886	Shared Neighborhood Hits	130
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

CCAR1_HUMAN
NC score	0.053425 (rank : 254)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	357	Target Neighborhood Hits	444	Shared Neighborhood Hits	140
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

MD1L1_HUMAN
NC score	0.053253 (rank : 255)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	357	Target Neighborhood Hits	893	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

CCD96_MOUSE
NC score	0.053230 (rank : 256)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	357	Target Neighborhood Hits	704	Shared Neighborhood Hits	138
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

AZI1_HUMAN
NC score	0.053142 (rank : 257)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	357	Target Neighborhood Hits	1000	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CP250_HUMAN
NC score	0.053112 (rank : 258)	θ value	4.03905 (rank : 265)
Query Neighborhood Hits	357	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP135_HUMAN
NC score	0.053087 (rank : 259)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	357	Target Neighborhood Hits	1290	Shared Neighborhood Hits	149
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRIPB_HUMAN
NC score	0.053079 (rank : 260)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	357	Target Neighborhood Hits	1587	Shared Neighborhood Hits	157
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCAR1_MOUSE
NC score	0.053079 (rank : 261)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CF010_HUMAN
NC score	0.053034 (rank : 262)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	357	Target Neighborhood Hits	329	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

IFT81_MOUSE
NC score	0.053023 (rank : 263)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	143
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

C102B_HUMAN
NC score	0.052992 (rank : 264)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	357	Target Neighborhood Hits	542	Shared Neighborhood Hits	113
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

TCAL5_HUMAN
NC score	0.052983 (rank : 265)	θ value	0.0961366 (rank : 146)
Query Neighborhood Hits	357	Target Neighborhood Hits	806	Shared Neighborhood Hits	95
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CCD39_HUMAN
NC score	0.052964 (rank : 266)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	357	Target Neighborhood Hits	868	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

MD1L1_MOUSE
NC score	0.052905 (rank : 267)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	357	Target Neighborhood Hits	1001	Shared Neighborhood Hits	132
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

SFRS4_MOUSE
NC score	0.052814 (rank : 268)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	357	Target Neighborhood Hits	406	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

MYH14_HUMAN
NC score	0.052800 (rank : 269)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	357	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

EEA1_HUMAN
NC score	0.052510 (rank : 270)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	357	Target Neighborhood Hits	1796	Shared Neighborhood Hits	163
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NIN_HUMAN
NC score	0.052388 (rank : 271)	θ value	5.27518 (rank : 304)
Query Neighborhood Hits	357	Target Neighborhood Hits	1416	Shared Neighborhood Hits	158
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

IFT81_HUMAN
NC score	0.052359 (rank : 272)	θ value	6.88961 (rank : 319)
Query Neighborhood Hits	357	Target Neighborhood Hits	893	Shared Neighborhood Hits	139
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

THOC2_HUMAN
NC score	0.052308 (rank : 273)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	357	Target Neighborhood Hits	337	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

GOGA6_HUMAN
NC score	0.052250 (rank : 274)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	357	Target Neighborhood Hits	1007	Shared Neighborhood Hits	149
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CCD41_HUMAN
NC score	0.052210 (rank : 275)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	357	Target Neighborhood Hits	1139	Shared Neighborhood Hits	139
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

TMF1_HUMAN
NC score	0.052010 (rank : 276)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	357	Target Neighborhood Hits	987	Shared Neighborhood Hits	145
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

RB6I2_MOUSE
NC score	0.051996 (rank : 277)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	357	Target Neighborhood Hits	1433	Shared Neighborhood Hits	161
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CEP63_HUMAN
NC score	0.051898 (rank : 278)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	357	Target Neighborhood Hits	1005	Shared Neighborhood Hits	139
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

MYO5C_HUMAN
NC score	0.051875 (rank : 279)	θ value	5.27518 (rank : 303)
Query Neighborhood Hits	357	Target Neighborhood Hits	1206	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CCD62_HUMAN
NC score	0.051855 (rank : 280)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	357	Target Neighborhood Hits	631	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CE290_HUMAN
NC score	0.051804 (rank : 281)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	357	Target Neighborhood Hits	1553	Shared Neighborhood Hits	163
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CROCC_HUMAN
NC score	0.051790 (rank : 282)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	357	Target Neighborhood Hits	1409	Shared Neighborhood Hits	158
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ARI4A_HUMAN
NC score	0.051781 (rank : 283)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	357	Target Neighborhood Hits	434	Shared Neighborhood Hits	126
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

NOP14_MOUSE
NC score	0.051762 (rank : 284)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	357	Target Neighborhood Hits	324	Shared Neighborhood Hits	103
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

SM1L2_HUMAN
NC score	0.051745 (rank : 285)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	357	Target Neighborhood Hits	1019	Shared Neighborhood Hits	141
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

GRAP1_HUMAN
NC score	0.051706 (rank : 286)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	357	Target Neighborhood Hits	944	Shared Neighborhood Hits	137
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

RPTN_MOUSE
NC score	0.051705 (rank : 287)	θ value	0.21417 (rank : 168)
Query Neighborhood Hits	357	Target Neighborhood Hits	650	Shared Neighborhood Hits	82
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TAXB1_HUMAN
NC score	0.051592 (rank : 288)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	357	Target Neighborhood Hits	829	Shared Neighborhood Hits	138
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

NEST_HUMAN
NC score	0.051588 (rank : 289)	θ value	4.03905 (rank : 276)
Query Neighborhood Hits	357	Target Neighborhood Hits	1305	Shared Neighborhood Hits	165
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

WDR60_MOUSE
NC score	0.051535 (rank : 290)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	357	Target Neighborhood Hits	344	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C761, Q3UNM4	Gene names	Wdr60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

IFT74_HUMAN
NC score	0.051515 (rank : 291)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	357	Target Neighborhood Hits	949	Shared Neighborhood Hits	133
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CCD91_HUMAN
NC score	0.051444 (rank : 292)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	357	Target Neighborhood Hits	868	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

MFAP1_MOUSE
NC score	0.051393 (rank : 293)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	357	Target Neighborhood Hits	353	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

AZI1_MOUSE
NC score	0.051369 (rank : 294)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	357	Target Neighborhood Hits	990	Shared Neighborhood Hits	148
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CRCM_HUMAN
NC score	0.051321 (rank : 295)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	357	Target Neighborhood Hits	520	Shared Neighborhood Hits	109
SwissProt Accessions	P23508	Gene names	MCC
Domain Architecture
Description	Colorectal mutant cancer protein (Protein MCC).

CCD21_MOUSE
NC score	0.051310 (rank : 296)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	357	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

LRRF2_MOUSE
NC score	0.051212 (rank : 297)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	357	Target Neighborhood Hits	556	Shared Neighborhood Hits	105
SwissProt Accessions	Q91WK0, Q8BVD1, Q9CU89	Gene names	Lrrfip2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

SMC2_MOUSE
NC score	0.051200 (rank : 298)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	357	Target Neighborhood Hits	1131	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

GOGA2_MOUSE
NC score	0.051163 (rank : 299)	θ value	0.62314 (rank : 189)
Query Neighborhood Hits	357	Target Neighborhood Hits	944	Shared Neighborhood Hits	124
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

LRC45_MOUSE
NC score	0.051163 (rank : 300)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	357	Target Neighborhood Hits	959	Shared Neighborhood Hits	136
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CJ118_HUMAN
NC score	0.051110 (rank : 301)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	357	Target Neighborhood Hits	937	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CIR_MOUSE
NC score	0.050974 (rank : 302)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	357	Target Neighborhood Hits	255	Shared Neighborhood Hits	80
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

OPTN_MOUSE
NC score	0.050895 (rank : 303)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	357	Target Neighborhood Hits	1120	Shared Neighborhood Hits	153
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

OPTN_HUMAN
NC score	0.050794 (rank : 304)	θ value	4.03905 (rank : 278)
Query Neighborhood Hits	357	Target Neighborhood Hits	827	Shared Neighborhood Hits	138
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

SKIV2_HUMAN
NC score	0.050793 (rank : 305)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	357	Target Neighborhood Hits	45	Shared Neighborhood Hits	20
SwissProt Accessions	Q15477, O15005, Q12902, Q15476	Gene names	SKIV2L, DDX13, SKI2W, SKIV2, W
Domain Architecture
Description	Helicase SKI2W (EC 3.6.1.-) (Helicase-like protein) (HLP).

RBCC1_HUMAN
NC score	0.050746 (rank : 306)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	357	Target Neighborhood Hits	1023	Shared Neighborhood Hits	148
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CF152_HUMAN
NC score	0.050734 (rank : 307)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	357	Target Neighborhood Hits	704	Shared Neighborhood Hits	128
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CENPF_HUMAN
NC score	0.050687 (rank : 308)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	357	Target Neighborhood Hits	1932	Shared Neighborhood Hits	173
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PEPL_MOUSE
NC score	0.050574 (rank : 309)	θ value	6.88961 (rank : 322)
Query Neighborhood Hits	357	Target Neighborhood Hits	1105	Shared Neighborhood Hits	148
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

LMD1_HUMAN
NC score	0.050443 (rank : 310)	θ value	0.163984 (rank : 164)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	42
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

CCHCR_MOUSE
NC score	0.050424 (rank : 311)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	357	Target Neighborhood Hits	932	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CN145_MOUSE
NC score	0.050326 (rank : 312)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	357	Target Neighborhood Hits	916	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

HMMR_HUMAN
NC score	0.050180 (rank : 313)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	357	Target Neighborhood Hits	1082	Shared Neighborhood Hits	139
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IFT74_MOUSE
NC score	0.050087 (rank : 314)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	357	Target Neighborhood Hits	939	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

GAS8_HUMAN
NC score	0.050013 (rank : 315)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	357	Target Neighborhood Hits	819	Shared Neighborhood Hits	129
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RB15B_HUMAN
NC score	0.049923 (rank : 316)	θ value	0.0961366 (rank : 144)
Query Neighborhood Hits	357	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

KIF4A_HUMAN
NC score	0.048934 (rank : 317)	θ value	0.0330416 (rank : 122)
Query Neighborhood Hits	357	Target Neighborhood Hits	1159	Shared Neighborhood Hits	153
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KINH_HUMAN
NC score	0.048687 (rank : 318)	θ value	0.62314 (rank : 190)
Query Neighborhood Hits	357	Target Neighborhood Hits	1231	Shared Neighborhood Hits	157
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

NKTR_HUMAN
NC score	0.048458 (rank : 319)	θ value	3.0926 (rank : 254)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	113
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

KINH_MOUSE
NC score	0.048359 (rank : 320)	θ value	0.125558 (rank : 148)
Query Neighborhood Hits	357	Target Neighborhood Hits	1082	Shared Neighborhood Hits	159
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

RFIP4_HUMAN
NC score	0.048304 (rank : 321)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	357	Target Neighborhood Hits	785	Shared Neighborhood Hits	122
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SRRM2_HUMAN
NC score	0.048025 (rank : 322)	θ value	1.81305 (rank : 235)
Query Neighborhood Hits	357	Target Neighborhood Hits	1296	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

PLCB4_HUMAN
NC score	0.047492 (rank : 323)	θ value	5.27518 (rank : 308)
Query Neighborhood Hits	357	Target Neighborhood Hits	658	Shared Neighborhood Hits	134
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

HOME2_MOUSE
NC score	0.047492 (rank : 324)	θ value	1.06291 (rank : 212)
Query Neighborhood Hits	357	Target Neighborhood Hits	882	Shared Neighborhood Hits	135
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

DMD_MOUSE
NC score	0.047099 (rank : 325)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	357	Target Neighborhood Hits	1111	Shared Neighborhood Hits	144
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

TUFT1_HUMAN
NC score	0.046550 (rank : 326)	θ value	5.27518 (rank : 311)
Query Neighborhood Hits	357	Target Neighborhood Hits	686	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CLCB_MOUSE
NC score	0.046498 (rank : 327)	θ value	0.0961366 (rank : 140)
Query Neighborhood Hits	357	Target Neighborhood Hits	119	Shared Neighborhood Hits	26
SwissProt Accessions	Q6IRU5, Q8BR04, Q8CDX9, Q9CV35	Gene names	Cltb
Domain Architecture	No domain graphic available
Description	Clathrin light chain B (Lcb).

SYNE2_HUMAN
NC score	0.046442 (rank : 328)	θ value	0.47712 (rank : 184)
Query Neighborhood Hits	357	Target Neighborhood Hits	1323	Shared Neighborhood Hits	153
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ANR12_HUMAN
NC score	0.046022 (rank : 329)	θ value	5.27518 (rank : 288)
Query Neighborhood Hits	357	Target Neighborhood Hits	1081	Shared Neighborhood Hits	172
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

SRRM2_MOUSE
NC score	0.045945 (rank : 330)	θ value	2.36792 (rank : 241)
Query Neighborhood Hits	357	Target Neighborhood Hits	1470	Shared Neighborhood Hits	108
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CLCB_HUMAN
NC score	0.045457 (rank : 331)	θ value	0.0736092 (rank : 135)
Query Neighborhood Hits	357	Target Neighborhood Hits	137	Shared Neighborhood Hits	22
SwissProt Accessions	P09497, Q6FHW1	Gene names	CLTB
Domain Architecture
Description	Clathrin light chain B (Lcb).

PLCB1_HUMAN
NC score	0.045075 (rank : 332)	θ value	0.125558 (rank : 154)
Query Neighborhood Hits	357	Target Neighborhood Hits	614	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NQ66, O60325, Q5TFF7, Q5TGC9, Q8IV93, Q9BQW2, Q9H4H2, Q9H8H5, Q9NQ65, Q9NQH9, Q9NTH4, Q9UJP6, Q9UM26	Gene names	PLCB1, KIAA0581
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

DNMT1_HUMAN
NC score	0.044834 (rank : 333)	θ value	4.03905 (rank : 267)
Query Neighborhood Hits	357	Target Neighborhood Hits	401	Shared Neighborhood Hits	93
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

MDN1_HUMAN
NC score	0.044775 (rank : 334)	θ value	5.27518 (rank : 302)
Query Neighborhood Hits	357	Target Neighborhood Hits	662	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

UACA_HUMAN
NC score	0.043916 (rank : 335)	θ value	0.813845 (rank : 207)
Query Neighborhood Hits	357	Target Neighborhood Hits	1622	Shared Neighborhood Hits	155
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

STIM1_MOUSE
NC score	0.043847 (rank : 336)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	357	Target Neighborhood Hits	660	Shared Neighborhood Hits	123
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STIM1_HUMAN
NC score	0.043396 (rank : 337)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	357	Target Neighborhood Hits	665	Shared Neighborhood Hits	119
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

ZN318_MOUSE
NC score	0.043279 (rank : 338)	θ value	1.38821 (rank : 229)
Query Neighborhood Hits	357	Target Neighborhood Hits	642	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

KI21A_HUMAN
NC score	0.042662 (rank : 339)	θ value	0.163984 (rank : 163)
Query Neighborhood Hits	357	Target Neighborhood Hits	1543	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

PLCB1_MOUSE
NC score	0.042540 (rank : 340)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	357	Target Neighborhood Hits	531	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SNW1_HUMAN
NC score	0.042530 (rank : 341)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	357	Target Neighborhood Hits	124	Shared Neighborhood Hits	34
SwissProt Accessions	Q13573, Q13483, Q32N03, Q5D0D6	Gene names	SNW1, SKIIP, SKIP
Domain Architecture
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein) (Nuclear receptor coactivator NCoA-62).

SNW1_MOUSE
NC score	0.042378 (rank : 342)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	357	Target Neighborhood Hits	125	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CSN1	Gene names	Snw1, Skiip
Domain Architecture	No domain graphic available
Description	SNW domain-containing protein 1 (Nuclear protein SkiP) (Ski- interacting protein).

SCG2_HUMAN
NC score	0.041104 (rank : 343)	θ value	0.0431538 (rank : 128)
Query Neighborhood Hits	357	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

RAI14_MOUSE
NC score	0.040658 (rank : 344)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	357	Target Neighborhood Hits	1505	Shared Neighborhood Hits	166
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR11_HUMAN
NC score	0.040605 (rank : 345)	θ value	0.163984 (rank : 159)
Query Neighborhood Hits	357	Target Neighborhood Hits	1289	Shared Neighborhood Hits	165
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NFM_MOUSE
NC score	0.040350 (rank : 346)	θ value	8.99809 (rank : 344)
Query Neighborhood Hits	357	Target Neighborhood Hits	1159	Shared Neighborhood Hits	189
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

EP15_MOUSE
NC score	0.040010 (rank : 347)	θ value	4.03905 (rank : 269)
Query Neighborhood Hits	357	Target Neighborhood Hits	820	Shared Neighborhood Hits	119
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

EP15_HUMAN
NC score	0.039847 (rank : 348)	θ value	5.27518 (rank : 294)
Query Neighborhood Hits	357	Target Neighborhood Hits	1021	Shared Neighborhood Hits	135
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TCAL3_MOUSE
NC score	0.039691 (rank : 349)	θ value	1.06291 (rank : 214)
Query Neighborhood Hits	357	Target Neighborhood Hits	132	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SMRC1_MOUSE
NC score	0.038868 (rank : 350)	θ value	0.279714 (rank : 172)
Query Neighborhood Hits	357	Target Neighborhood Hits	459	Shared Neighborhood Hits	89
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

MATR3_MOUSE
NC score	0.038378 (rank : 351)	θ value	5.27518 (rank : 301)
Query Neighborhood Hits	357	Target Neighborhood Hits	321	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

KIF4A_MOUSE
NC score	0.037598 (rank : 352)	θ value	5.27518 (rank : 300)
Query Neighborhood Hits	357	Target Neighborhood Hits	1033	Shared Neighborhood Hits	142
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SMRC1_HUMAN
NC score	0.036958 (rank : 353)	θ value	0.62314 (rank : 196)
Query Neighborhood Hits	357	Target Neighborhood Hits	375	Shared Neighborhood Hits	74
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

MATR3_HUMAN
NC score	0.036917 (rank : 354)	θ value	0.47712 (rank : 180)
Query Neighborhood Hits	357	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

RBM6_HUMAN
NC score	0.036652 (rank : 355)	θ value	0.0736092 (rank : 137)
Query Neighborhood Hits	357	Target Neighborhood Hits	221	Shared Neighborhood Hits	30
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

RPTN_HUMAN
NC score	0.036419 (rank : 356)	θ value	3.0926 (rank : 259)
Query Neighborhood Hits	357	Target Neighborhood Hits	406	Shared Neighborhood Hits	56
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TCAL6_HUMAN
NC score	0.036227 (rank : 357)	θ value	3.0926 (rank : 262)
Query Neighborhood Hits	357	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

YLPM1_HUMAN
NC score	0.035846 (rank : 358)	θ value	0.0961366 (rank : 147)
Query Neighborhood Hits	357	Target Neighborhood Hits	670	Shared Neighborhood Hits	49
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BCLF1_MOUSE
NC score	0.035495 (rank : 359)	θ value	8.99809 (rank : 336)
Query Neighborhood Hits	357	Target Neighborhood Hits	303	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K019, Q8BNZ0, Q8C2E9, Q9CSW5	Gene names	Bclaf1, Btf, Kiaa0164
Domain Architecture	No domain graphic available
Description	Bcl-2-associated transcription factor 1 (Btf).

ITSN1_MOUSE
NC score	0.034840 (rank : 360)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	357	Target Neighborhood Hits	1669	Shared Neighborhood Hits	170
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

TTC16_HUMAN
NC score	0.034819 (rank : 361)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	357	Target Neighborhood Hits	417	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

GASP2_MOUSE
NC score	0.033755 (rank : 362)	θ value	0.0113563 (rank : 110)
Query Neighborhood Hits	357	Target Neighborhood Hits	228	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

MRCKB_HUMAN
NC score	0.033451 (rank : 363)	θ value	3.19293e-05 (rank : 82)
Query Neighborhood Hits	357	Target Neighborhood Hits	2239	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PPIP2_MOUSE
NC score	0.033300 (rank : 364)	θ value	1.38821 (rank : 223)
Query Neighborhood Hits	357	Target Neighborhood Hits	308	Shared Neighborhood Hits	79
SwissProt Accessions	Q99M15, Q9Z189	Gene names	Pstpip2, Mayp
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2 (Macrophage actin-associated tyrosine-phosphorylated protein) (pp37).

STIM2_HUMAN
NC score	0.032749 (rank : 365)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	357	Target Neighborhood Hits	420	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

DZIP1_HUMAN
NC score	0.032544 (rank : 366)	θ value	8.99809 (rank : 340)
Query Neighborhood Hits	357	Target Neighborhood Hits	675	Shared Neighborhood Hits	92
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

MRCKB_MOUSE
NC score	0.032390 (rank : 367)	θ value	0.000158464 (rank : 90)
Query Neighborhood Hits	357	Target Neighborhood Hits	2180	Shared Neighborhood Hits	162
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

AKAP6_HUMAN
NC score	0.032208 (rank : 368)	θ value	4.03905 (rank : 264)
Query Neighborhood Hits	357	Target Neighborhood Hits	263	Shared Neighborhood Hits	55
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

PRP16_HUMAN
NC score	0.032064 (rank : 369)	θ value	1.38821 (rank : 224)
Query Neighborhood Hits	357	Target Neighborhood Hits	135	Shared Neighborhood Hits	50
SwissProt Accessions	Q92620, O75212, Q96HN7	Gene names	DHX38, DDX38, KIAA0224, PRP16
Domain Architecture
Description	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (EC 3.6.1.-) (ATP-dependent RNA helicase DHX38) (DEAH box protein 38).

STIM2_MOUSE
NC score	0.032045 (rank : 370)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	97
SwissProt Accessions	P83093, Q69ZI3, Q80VF4	Gene names	Stim2, Kiaa1482
Domain Architecture	No domain graphic available
Description	Stromal interaction molecule 2 precursor.

CHCH3_MOUSE
NC score	0.031845 (rank : 371)	θ value	2.36792 (rank : 237)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

DMN_HUMAN
NC score	0.031126 (rank : 372)	θ value	1.06291 (rank : 210)
Query Neighborhood Hits	357	Target Neighborhood Hits	690	Shared Neighborhood Hits	122
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

EZRI_HUMAN
NC score	0.031097 (rank : 373)	θ value	6.88961 (rank : 315)
Query Neighborhood Hits	357	Target Neighborhood Hits	663	Shared Neighborhood Hits	133
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

CTRO_MOUSE
NC score	0.031085 (rank : 374)	θ value	0.0961366 (rank : 141)
Query Neighborhood Hits	357	Target Neighborhood Hits	2344	Shared Neighborhood Hits	179
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PERQ1_MOUSE
NC score	0.030428 (rank : 375)	θ value	2.36792 (rank : 240)
Query Neighborhood Hits	357	Target Neighborhood Hits	215	Shared Neighborhood Hits	57
SwissProt Accessions	Q99MR1	Gene names	Perq1
Domain Architecture
Description	PERQ amino acid rich with GYF domain protein 1.

SEC63_HUMAN
NC score	0.030204 (rank : 376)	θ value	1.38821 (rank : 225)
Query Neighborhood Hits	357	Target Neighborhood Hits	586	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

JIP3_MOUSE
NC score	0.030030 (rank : 377)	θ value	4.03905 (rank : 272)
Query Neighborhood Hits	357	Target Neighborhood Hits	759	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MAGI1_MOUSE
NC score	0.029805 (rank : 378)	θ value	0.0148317 (rank : 116)
Query Neighborhood Hits	357	Target Neighborhood Hits	403	Shared Neighborhood Hits	46
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

CJ078_MOUSE
NC score	0.029454 (rank : 379)	θ value	5.27518 (rank : 291)
Query Neighborhood Hits	357	Target Neighborhood Hits	559	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

APOA1_HUMAN
NC score	0.028906 (rank : 380)	θ value	6.88961 (rank : 313)
Query Neighborhood Hits	357	Target Neighborhood Hits	262	Shared Neighborhood Hits	61
SwissProt Accessions	P02647, Q6LDN9, Q6Q785	Gene names	APOA1
Domain Architecture
Description	Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein A-I(1-242)].

UBP8_HUMAN
NC score	0.028480 (rank : 381)	θ value	2.36792 (rank : 243)
Query Neighborhood Hits	357	Target Neighborhood Hits	751	Shared Neighborhood Hits	153
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

HSP74_MOUSE
NC score	0.028359 (rank : 382)	θ value	0.0961366 (rank : 142)
Query Neighborhood Hits	357	Target Neighborhood Hits	257	Shared Neighborhood Hits	75
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

SEC63_MOUSE
NC score	0.027734 (rank : 383)	θ value	3.0926 (rank : 261)
Query Neighborhood Hits	357	Target Neighborhood Hits	601	Shared Neighborhood Hits	77
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

CHD9_MOUSE
NC score	0.026404 (rank : 384)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	357	Target Neighborhood Hits	427	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ZN277_HUMAN
NC score	0.026377 (rank : 385)	θ value	0.47712 (rank : 186)
Query Neighborhood Hits	357	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRM2	Gene names	ZNF277
Domain Architecture	No domain graphic available
Description	Zinc finger protein 277.

ROCK1_MOUSE
NC score	0.026155 (rank : 386)	θ value	4.03905 (rank : 280)
Query Neighborhood Hits	357	Target Neighborhood Hits	2126	Shared Neighborhood Hits	163
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ADDB_MOUSE
NC score	0.025987 (rank : 387)	θ value	1.81305 (rank : 230)
Query Neighborhood Hits	357	Target Neighborhood Hits	574	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

DHX34_MOUSE
NC score	0.025853 (rank : 388)	θ value	0.0148317 (rank : 114)
Query Neighborhood Hits	357	Target Neighborhood Hits	235	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

XYLT1_MOUSE
NC score	0.025050 (rank : 389)	θ value	0.125558 (rank : 158)
Query Neighborhood Hits	357	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

DHX36_MOUSE
NC score	0.024683 (rank : 390)	θ value	8.99809 (rank : 339)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

DHX36_HUMAN
NC score	0.024352 (rank : 391)	θ value	1.81305 (rank : 232)
Query Neighborhood Hits	357	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H2U1, Q70JU3, Q8IYE5, Q9P240	Gene names	DHX36, DDX36, KIAA1488, MLEL1, RHAU
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

TMC2_MOUSE
NC score	0.024029 (rank : 392)	θ value	4.03905 (rank : 283)
Query Neighborhood Hits	357	Target Neighborhood Hits	249	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

STK10_MOUSE
NC score	0.023810 (rank : 393)	θ value	0.62314 (rank : 197)
Query Neighborhood Hits	357	Target Neighborhood Hits	2132	Shared Neighborhood Hits	184
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

DZIP3_MOUSE
NC score	0.023441 (rank : 394)	θ value	8.99809 (rank : 341)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

LRC27_HUMAN
NC score	0.023345 (rank : 395)	θ value	1.81305 (rank : 234)
Query Neighborhood Hits	357	Target Neighborhood Hits	710	Shared Neighborhood Hits	90
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

MAGI1_HUMAN
NC score	0.023037 (rank : 396)	θ value	0.163984 (rank : 165)
Query Neighborhood Hits	357	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

CLCA_HUMAN
NC score	0.022953 (rank : 397)	θ value	6.88961 (rank : 314)
Query Neighborhood Hits	357	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

DIDO1_HUMAN
NC score	0.022667 (rank : 398)	θ value	5.27518 (rank : 293)
Query Neighborhood Hits	357	Target Neighborhood Hits	960	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

ROCK1_HUMAN
NC score	0.022044 (rank : 399)	θ value	6.88961 (rank : 327)
Query Neighborhood Hits	357	Target Neighborhood Hits	2000	Shared Neighborhood Hits	151
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK2_HUMAN
NC score	0.021391 (rank : 400)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	357	Target Neighborhood Hits	2073	Shared Neighborhood Hits	159
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

UBXD2_MOUSE
NC score	0.021237 (rank : 401)	θ value	5.27518 (rank : 312)
Query Neighborhood Hits	357	Target Neighborhood Hits	183	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

SURF6_HUMAN
NC score	0.020787 (rank : 402)	θ value	5.27518 (rank : 309)
Query Neighborhood Hits	357	Target Neighborhood Hits	104	Shared Neighborhood Hits	30
SwissProt Accessions	O75683, Q9BRK9, Q9BTZ5, Q9UK24	Gene names	SURF6, SURF-6
Domain Architecture
Description	Surfeit locus protein 6.

PCLO_MOUSE
NC score	0.020634 (rank : 403)	θ value	1.38821 (rank : 222)
Query Neighborhood Hits	357	Target Neighborhood Hits	2275	Shared Neighborhood Hits	150
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PACN3_HUMAN
NC score	0.020495 (rank : 404)	θ value	0.47712 (rank : 183)
Query Neighborhood Hits	357	Target Neighborhood Hits	385	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

GP179_HUMAN
NC score	0.020492 (rank : 405)	θ value	1.06291 (rank : 211)
Query Neighborhood Hits	357	Target Neighborhood Hits	372	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

R51A1_MOUSE
NC score	0.020075 (rank : 406)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	357	Target Neighborhood Hits	164	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

SP110_HUMAN
NC score	0.019862 (rank : 407)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

UBP1_HUMAN
NC score	0.019559 (rank : 408)	θ value	2.36792 (rank : 242)
Query Neighborhood Hits	357	Target Neighborhood Hits	259	Shared Neighborhood Hits	51
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

XPC_MOUSE
NC score	0.018901 (rank : 409)	θ value	2.36792 (rank : 244)
Query Neighborhood Hits	357	Target Neighborhood Hits	75	Shared Neighborhood Hits	18
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

IF4B_HUMAN
NC score	0.018810 (rank : 410)	θ value	6.88961 (rank : 318)
Query Neighborhood Hits	357	Target Neighborhood Hits	417	Shared Neighborhood Hits	32
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TAOK1_HUMAN
NC score	0.018091 (rank : 411)	θ value	0.47712 (rank : 185)
Query Neighborhood Hits	357	Target Neighborhood Hits	1734	Shared Neighborhood Hits	152
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

UBP8_MOUSE
NC score	0.017899 (rank : 412)	θ value	4.03905 (rank : 285)
Query Neighborhood Hits	357	Target Neighborhood Hits	362	Shared Neighborhood Hits	84
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

WDHD1_MOUSE
NC score	0.017803 (rank : 413)	θ value	0.125558 (rank : 157)
Query Neighborhood Hits	357	Target Neighborhood Hits	414	Shared Neighborhood Hits	22
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

NUCL_HUMAN
NC score	0.017749 (rank : 414)	θ value	5.27518 (rank : 305)
Query Neighborhood Hits	357	Target Neighborhood Hits	415	Shared Neighborhood Hits	49
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

TAOK1_MOUSE
NC score	0.017447 (rank : 415)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	357	Target Neighborhood Hits	1720	Shared Neighborhood Hits	150
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

OCLN_HUMAN
NC score	0.016887 (rank : 416)	θ value	3.0926 (rank : 255)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	31
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

OCLN_MOUSE
NC score	0.016820 (rank : 417)	θ value	4.03905 (rank : 277)
Query Neighborhood Hits	357	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q61146, Q544A7	Gene names	Ocln, Ocl
Domain Architecture
Description	Occludin.

STK10_HUMAN
NC score	0.016729 (rank : 418)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	357	Target Neighborhood Hits	1921	Shared Neighborhood Hits	155
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GASP1_MOUSE
NC score	0.016727 (rank : 419)	θ value	6.88961 (rank : 317)
Query Neighborhood Hits	357	Target Neighborhood Hits	169	Shared Neighborhood Hits	24
SwissProt Accessions	Q5U4C1, Q8BKR8, Q8BUN4, Q8BYK9, Q8CHF4, Q8R095	Gene names	Gprasp1, Kiaa0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

PF21B_HUMAN
NC score	0.016407 (rank : 420)	θ value	0.62314 (rank : 193)
Query Neighborhood Hits	357	Target Neighborhood Hits	197	Shared Neighborhood Hits	17
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SLK_MOUSE
NC score	0.016284 (rank : 421)	θ value	0.0961366 (rank : 145)
Query Neighborhood Hits	357	Target Neighborhood Hits	1798	Shared Neighborhood Hits	160
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

XYLT1_HUMAN
NC score	0.015892 (rank : 422)	θ value	1.38821 (rank : 228)
Query Neighborhood Hits	357	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q86Y38, Q9H1B6	Gene names	XYLT1, XT1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (XylT-I) (XT-I) (Peptide O-xylosyltransferase 1).

HSP74_HUMAN
NC score	0.015876 (rank : 423)	θ value	4.03905 (rank : 271)
Query Neighborhood Hits	357	Target Neighborhood Hits	154	Shared Neighborhood Hits	49
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

SLK_HUMAN
NC score	0.015746 (rank : 424)	θ value	0.125558 (rank : 155)
Query Neighborhood Hits	357	Target Neighborhood Hits	1775	Shared Neighborhood Hits	159
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

EST1A_MOUSE
NC score	0.015136 (rank : 425)	θ value	5.27518 (rank : 296)
Query Neighborhood Hits	357	Target Neighborhood Hits	138	Shared Neighborhood Hits	30
SwissProt Accessions	P61406, Q5NC64	Gene names	Est1a, Kiaa0732
Domain Architecture
Description	Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A).

ADDB_HUMAN
NC score	0.014991 (rank : 426)	θ value	2.36792 (rank : 236)
Query Neighborhood Hits	357	Target Neighborhood Hits	142	Shared Neighborhood Hits	26
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

TRI29_MOUSE
NC score	0.014457 (rank : 427)	θ value	4.03905 (rank : 284)
Query Neighborhood Hits	357	Target Neighborhood Hits	306	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

PACN3_MOUSE
NC score	0.014449 (rank : 428)	θ value	3.0926 (rank : 256)
Query Neighborhood Hits	357	Target Neighborhood Hits	380	Shared Neighborhood Hits	56
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

E41L1_HUMAN
NC score	0.014353 (rank : 429)	θ value	0.163984 (rank : 162)
Query Neighborhood Hits	357	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

NUFP1_MOUSE
NC score	0.014326 (rank : 430)	θ value	0.62314 (rank : 192)
Query Neighborhood Hits	357	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QXX8, Q9CV69	Gene names	Nufip1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1).

GRP78_HUMAN
NC score	0.014172 (rank : 431)	θ value	2.36792 (rank : 238)
Query Neighborhood Hits	357	Target Neighborhood Hits	218	Shared Neighborhood Hits	54
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.014006 (rank : 432)	θ value	2.36792 (rank : 239)
Query Neighborhood Hits	357	Target Neighborhood Hits	216	Shared Neighborhood Hits	52
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

CAC1A_HUMAN
NC score	0.012690 (rank : 433)	θ value	0.163984 (rank : 160)
Query Neighborhood Hits	357	Target Neighborhood Hits	387	Shared Neighborhood Hits	33
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

FMN1B_MOUSE
NC score	0.012418 (rank : 434)	θ value	6.88961 (rank : 316)
Query Neighborhood Hits	357	Target Neighborhood Hits	447	Shared Neighborhood Hits	54
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

SETD8_MOUSE
NC score	0.012409 (rank : 435)	θ value	1.38821 (rank : 226)
Query Neighborhood Hits	357	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SVIL_MOUSE
NC score	0.011973 (rank : 436)	θ value	5.27518 (rank : 310)
Query Neighborhood Hits	357	Target Neighborhood Hits	439	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K4L3	Gene names	Svil
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

NOL3_HUMAN
NC score	0.011785 (rank : 437)	θ value	8.99809 (rank : 346)
Query Neighborhood Hits	357	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	O60936, O60937	Gene names	NOL3, ARC, NOP
Domain Architecture
Description	Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30).

JHD2C_HUMAN
NC score	0.011665 (rank : 438)	θ value	8.99809 (rank : 343)
Query Neighborhood Hits	357	Target Neighborhood Hits	279	Shared Neighborhood Hits	40
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

RIMS1_HUMAN
NC score	0.011038 (rank : 439)	θ value	3.0926 (rank : 258)
Query Neighborhood Hits	357	Target Neighborhood Hits	437	Shared Neighborhood Hits	36
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PPIL4_HUMAN
NC score	0.010256 (rank : 440)	θ value	6.88961 (rank : 325)
Query Neighborhood Hits	357	Target Neighborhood Hits	264	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUA2, Q7Z3Q5	Gene names	PPIL4
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase-like 4 (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-like protein PPIL4).

IF2M_MOUSE
NC score	0.010239 (rank : 441)	θ value	5.27518 (rank : 299)
Query Neighborhood Hits	357	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YJ5	Gene names	Mtif2
Domain Architecture
Description	Translation initiation factor IF-2, mitochondrial precursor (IF-2Mt) (IF-2(Mt)).

PSMD2_MOUSE
NC score	0.010115 (rank : 442)	θ value	8.99809 (rank : 348)
Query Neighborhood Hits	357	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

DIAP2_MOUSE
NC score	0.010101 (rank : 443)	θ value	3.0926 (rank : 249)
Query Neighborhood Hits	357	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

MYPT1_MOUSE
NC score	0.008964 (rank : 444)	θ value	6.88961 (rank : 321)
Query Neighborhood Hits	357	Target Neighborhood Hits	539	Shared Neighborhood Hits	82
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PINX1_HUMAN
NC score	0.008808 (rank : 445)	θ value	5.27518 (rank : 307)
Query Neighborhood Hits	357	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q96BK5, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2	Gene names	PINX1, LPTS
Domain Architecture
Description	Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver- related putative tumor suppressor) (67-11-3 protein).

DCDC2_HUMAN
NC score	0.008653 (rank : 446)	θ value	5.27518 (rank : 292)
Query Neighborhood Hits	357	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

PARP2_HUMAN
NC score	0.008296 (rank : 447)	θ value	5.27518 (rank : 306)
Query Neighborhood Hits	357	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

K1718_HUMAN
NC score	0.007897 (rank : 448)	θ value	4.03905 (rank : 273)
Query Neighborhood Hits	357	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

TRI17_MOUSE
NC score	0.007498 (rank : 449)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	357	Target Neighborhood Hits	620	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

YETS2_HUMAN
NC score	0.007444 (rank : 450)	θ value	4.03905 (rank : 286)
Query Neighborhood Hits	357	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

PDCL3_MOUSE
NC score	0.006667 (rank : 451)	θ value	4.03905 (rank : 279)
Query Neighborhood Hits	357	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

TTLL5_MOUSE
NC score	0.006549 (rank : 452)	θ value	3.0926 (rank : 263)
Query Neighborhood Hits	357	Target Neighborhood Hits	150	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

BRD7_MOUSE
NC score	0.005605 (rank : 453)	θ value	5.27518 (rank : 289)
Query Neighborhood Hits	357	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

SRBS1_MOUSE
NC score	0.003333 (rank : 454)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	357	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PABP1_HUMAN
NC score	0.002314 (rank : 455)	θ value	8.99809 (rank : 347)
Query Neighborhood Hits	357	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

GNAS1_MOUSE
NC score	0.000217 (rank : 456)	θ value	8.99809 (rank : 342)
Query Neighborhood Hits	357	Target Neighborhood Hits	651	Shared Neighborhood Hits	24
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

ABCA2_HUMAN
NC score	0.000106 (rank : 457)	θ value	8.99809 (rank : 335)
Query Neighborhood Hits	357	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ZN512_HUMAN
NC score	0.000005 (rank : 458)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	357	Target Neighborhood Hits	444	Shared Neighborhood Hits	4
SwissProt Accessions	Q96ME7, Q96JM0	Gene names	ZNF512, KIAA1805
Domain Architecture	No domain graphic available
Description	Zinc finger protein 512.

NMDE1_HUMAN
NC score	-0.000008 (rank : 459)	θ value	8.99809 (rank : 345)
Query Neighborhood Hits	357	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

SPEG_MOUSE
NC score	-0.001557 (rank : 460)	θ value	6.88961 (rank : 329)
Query Neighborhood Hits	357	Target Neighborhood Hits	1959	Shared Neighborhood Hits	56
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DCAK3_MOUSE
NC score	-0.002883 (rank : 461)	θ value	8.99809 (rank : 338)
Query Neighborhood Hits	357	Target Neighborhood Hits	922	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

SPEG_HUMAN
NC score	-0.003278 (rank : 462)	θ value	6.88961 (rank : 328)
Query Neighborhood Hits	357	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PLK4_HUMAN
NC score	-0.004473 (rank : 463)	θ value	6.88961 (rank : 324)
Query Neighborhood Hits	357	Target Neighborhood Hits	884	Shared Neighborhood Hits	20
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

ZKSC1_HUMAN
NC score	-0.005326 (rank : 464)	θ value	0.0563607 (rank : 134)
Query Neighborhood Hits	357	Target Neighborhood Hits	949	Shared Neighborhood Hits	44
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

HELI_MOUSE
NC score	-0.008332 (rank : 465)	θ value	5.27518 (rank : 298)
Query Neighborhood Hits	357	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	P81183	Gene names	Ikzf2, Helios, Zfpn1a2, Znfn1a2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).