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Network neighborhood for query Sequence : HSP74_HUMAN

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HSP74_HUMAN
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS105_HUMAN
θ value	0 (rank : 1)	NC score	0.978457 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	0 (rank : 2)	NC score	0.984074 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_HUMAN
θ value	0 (rank : 3)	NC score	0.979285 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_MOUSE
θ value	0 (rank : 4)	NC score	0.981192 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	44
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HSP74_MOUSE
θ value	0 (rank : 6)	NC score	0.980190 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	257	Shared Neighborhood Hits	98
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HSP76_HUMAN
θ value	3.12697e-77 (rank : 7)	NC score	0.903790 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

OXRP_HUMAN
θ value	2.64714e-76 (rank : 8)	NC score	0.897057 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	544	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

HSP71_HUMAN
θ value	2.92676e-75 (rank : 9)	NC score	0.902349 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70L_HUMAN
θ value	3.82246e-75 (rank : 10)	NC score	0.903191 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70A_MOUSE
θ value	1.45253e-74 (rank : 11)	NC score	0.902589 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	73	Shared Neighborhood Hits	33
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	1.45253e-74 (rank : 12)	NC score	0.902604 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HSP7C_HUMAN
θ value	3.23591e-74 (rank : 13)	NC score	0.901046 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	48
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	3.23591e-74 (rank : 14)	NC score	0.900677 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HS70L_MOUSE
θ value	1.22964e-73 (rank : 15)	NC score	0.903799 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

GRP78_MOUSE
θ value	7.97034e-73 (rank : 16)	NC score	0.897542 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	216	Shared Neighborhood Hits	58
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP78_HUMAN
θ value	1.04096e-72 (rank : 17)	NC score	0.897503 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	218	Shared Neighborhood Hits	59
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

HSP72_HUMAN
θ value	4.09345e-69 (rank : 18)	NC score	0.900012 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
θ value	1.19101e-68 (rank : 19)	NC score	0.899772 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

GRP75_MOUSE
θ value	2.57589e-55 (rank : 20)	NC score	0.902977 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
θ value	4.39379e-55 (rank : 21)	NC score	0.901848 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	33
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

STCH_HUMAN
θ value	5.21438e-40 (rank : 22)	NC score	0.895259 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
θ value	8.32485e-38 (rank : 23)	NC score	0.890749 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

MYO5B_HUMAN
θ value	0.000602161 (rank : 24)	NC score	0.045535 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	911	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

FLIP1_HUMAN
θ value	0.00175202 (rank : 25)	NC score	0.066935 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	1405	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SYCP1_MOUSE
θ value	0.00228821 (rank : 26)	NC score	0.077015 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	1456	Shared Neighborhood Hits	92
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BICD2_MOUSE
θ value	0.0148317 (rank : 27)	NC score	0.060547 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	864	Shared Neighborhood Hits	82
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

STK10_MOUSE
θ value	0.0148317 (rank : 28)	NC score	0.019118 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	2132	Shared Neighborhood Hits	92
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

GCC2_HUMAN
θ value	0.0193708 (rank : 29)	NC score	0.058614 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	1558	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

KI21B_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.042032 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	1017	Shared Neighborhood Hits	83
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

RBP24_HUMAN
θ value	0.0193708 (rank : 31)	NC score	0.058674 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	1559	Shared Neighborhood Hits	91
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SYCP1_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.072915 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	1313	Shared Neighborhood Hits	95
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

PLCB4_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.048484 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	658	Shared Neighborhood Hits	72
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

SMC3_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.068591 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	1186	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.0330416 (rank : 35)	NC score	0.068678 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	1187	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

LEO1_HUMAN
θ value	0.0431538 (rank : 36)	NC score	0.045713 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CCD91_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.081216 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

HMMR_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.052259 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	1178	Shared Neighborhood Hits	85
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

LRC45_MOUSE
θ value	0.0563607 (rank : 39)	NC score	0.047347 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

SPRL1_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.045714 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

ADA30_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.012519 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

REST_MOUSE
θ value	0.0736092 (rank : 42)	NC score	0.060816 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	1506	Shared Neighborhood Hits	93
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

AKAP2_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.048034 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CENPE_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.054998 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	2060	Shared Neighborhood Hits	102
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GOGA5_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.052255 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	1168	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

K0256_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.041224 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

GOGA4_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.062798 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	2034	Shared Neighborhood Hits	102
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RAD50_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.055102 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	1317	Shared Neighborhood Hits	87
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CCD46_MOUSE
θ value	0.279714 (rank : 49)	NC score	0.053508 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	1405	Shared Neighborhood Hits	93
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

MAP1A_HUMAN
θ value	0.279714 (rank : 50)	NC score	0.054028 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	1626	Shared Neighborhood Hits	98
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TTF1_MOUSE
θ value	0.279714 (rank : 51)	NC score	0.039239 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

RAD50_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.051293 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	1366	Shared Neighborhood Hits	87
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CTGE2_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.047155 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	594	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

IFT74_HUMAN
θ value	0.47712 (rank : 54)	NC score	0.047476 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	949	Shared Neighborhood Hits	77
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IWS1_MOUSE
θ value	0.47712 (rank : 55)	NC score	0.036825 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	1258	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RYR1_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.036597 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

BPA1_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.049643 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	1477	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.052071 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	1369	Shared Neighborhood Hits	85
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DYHC_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.042307 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	733	Shared Neighborhood Hits	71
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.042277 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	729	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

EEA1_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.046350 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	1637	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FLIP1_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.060662 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	1176	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MACF1_MOUSE
θ value	0.62314 (rank : 63)	NC score	0.040465 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	1313	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RAI14_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.039450 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	1505	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

BICD2_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.052691 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	856	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CCD46_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.051860 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	1430	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CJ068_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.045304 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	316	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

MY18A_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.041033 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	1929	Shared Neighborhood Hits	100
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH11_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.060096 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	1806	Shared Neighborhood Hits	110
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCNT_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.042260 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	1551	Shared Neighborhood Hits	85
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RAD_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.008644 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).

TITIN_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.011360 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	2923	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ALMS1_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.014080 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

CCD11_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.058058 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	822	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CYLN2_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.048011 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	1004	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ENKUR_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.073752 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

INVO_MOUSE
θ value	1.38821 (rank : 77)	NC score	0.052758 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	474	Shared Neighborhood Hits	61
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

SMCE1_MOUSE
θ value	1.38821 (rank : 78)	NC score	0.042269 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	409	Shared Neighborhood Hits	49
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

ANR26_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.039701 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	1614	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCD62_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.050576 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	631	Shared Neighborhood Hits	71
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

DAXX_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.031774 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

GCC2_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.058449 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KIF23_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.049767 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	618	Shared Neighborhood Hits	70
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

LEO1_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.032083 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	43
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PEG3_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.001554 (rank : 190)
Query Neighborhood Hits	154	Target Neighborhood Hits	1101	Shared Neighborhood Hits	26
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PPIG_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.024573 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	670	Shared Neighborhood Hits	66
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

EGR3_HUMAN
θ value	2.36792 (rank : 87)	NC score	-0.000568 (rank : 192)
Query Neighborhood Hits	154	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

MYH9_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.055700 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	1829	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO5C_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.040199 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	1206	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RUFY2_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.039859 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	1208	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

UBP10_MOUSE
θ value	2.36792 (rank : 91)	NC score	0.016758 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

ANK3_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.005585 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	853	Shared Neighborhood Hits	40
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CJ078_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.028970 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	559	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CR034_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.045500 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

DMN_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.020296 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

EGR3_MOUSE
θ value	3.0926 (rank : 96)	NC score	-0.000825 (rank : 194)
Query Neighborhood Hits	154	Target Neighborhood Hits	747	Shared Neighborhood Hits	7
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

HMMR_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.065429 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IWS1_HUMAN
θ value	3.0926 (rank : 98)	NC score	0.032426 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	1241	Shared Neighborhood Hits	60
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KIF3A_MOUSE
θ value	3.0926 (rank : 99)	NC score	0.037801 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	715	Shared Neighborhood Hits	77
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

RAD_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.006803 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	O88667	Gene names	Rrad
Domain Architecture
Description	GTP-binding protein RAD.

RBBP6_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.020311 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

REST_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.058077 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	1605	Shared Neighborhood Hits	98
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SLIT3_MOUSE
θ value	3.0926 (rank : 103)	NC score	-0.000603 (rank : 193)
Query Neighborhood Hits	154	Target Neighborhood Hits	700	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ZN710_MOUSE
θ value	3.0926 (rank : 104)	NC score	-0.003479 (rank : 195)
Query Neighborhood Hits	154	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

CP250_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.046271 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	1583	Shared Neighborhood Hits	89
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DDX46_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.015876 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	357	Shared Neighborhood Hits	49
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DDX46_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.016252 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	358	Shared Neighborhood Hits	49
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DLEC1_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.010820 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

DOPO_HUMAN
θ value	4.03905 (rank : 109)	NC score	0.015832 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P09172, Q5T381, Q96AG2	Gene names	DBH
Domain Architecture
Description	Dopamine beta-hydroxylase precursor (EC 1.14.17.1) (Dopamine beta- monooxygenase).

GOGA5_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.041128 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	1434	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

IRAK1_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.000462 (rank : 191)
Query Neighborhood Hits	154	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

KIF3A_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.039398 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	704	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

LIPA2_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.048712 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	1282	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MOES_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.033449 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	923	Shared Neighborhood Hits	80
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYH11_MOUSE
θ value	4.03905 (rank : 115)	NC score	0.055208 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	1777	Shared Neighborhood Hits	104
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.058805 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	1762	Shared Neighborhood Hits	107
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OTOF_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.006285 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SMCA2_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.007485 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ZNF18_HUMAN
θ value	4.03905 (rank : 119)	NC score	-0.003483 (rank : 196)
Query Neighborhood Hits	154	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	P17022, Q5QHQ3, Q8IYC4, Q8NAH6	Gene names	ZNF18, HDSG1, KOX11
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein KOX11) (Heart development- specific gene 1 protein).

BRE1A_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.051983 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	1071	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CCD41_MOUSE
θ value	5.27518 (rank : 121)	NC score	0.042557 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CYLC1_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.047762 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

FEZ2_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.017039 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

GCC1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.045144 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	777	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGB1_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.061612 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HOME2_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.035068 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	532	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

HS12B_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.095804 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

MYH3_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.040967 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	1660	Shared Neighborhood Hits	97
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NACAM_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.003119 (rank : 188)
Query Neighborhood Hits	154	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RBCC1_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.050295 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	1023	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CI093_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.045436 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	1088	Shared Neighborhood Hits	82
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CK5P2_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.042030 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	1151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

DEK_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.044664 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	280	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

KTN1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.045083 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	1324	Shared Neighborhood Hits	87
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PCIF1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.039356 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

PRLPK_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.004600 (rank : 183)
Query Neighborhood Hits	154	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAZ2, Q2TA52	Gene names	Prlpk
Domain Architecture	No domain graphic available
Description	Placental prolactin-like protein K precursor (PRL-like protein K) (PLP-K).

SPTB2_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.034345 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	770	Shared Neighborhood Hits	75
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CCD91_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.061091 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	699	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CJ118_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.048964 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

DDX21_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.003749 (rank : 186)
Query Neighborhood Hits	154	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

FACD2_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.010550 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

FEZ2_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.018333 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

GP73_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.035881 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	506	Shared Neighborhood Hits	69
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

MRCKA_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.027177 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	1999	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

NCKX1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.014299 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

REM1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.002079 (rank : 189)
Query Neighborhood Hits	154	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

RFFL_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.004273 (rank : 185)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RPTN_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.007456 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	650	Shared Neighborhood Hits	32
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RTEL1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.004680 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

TGON2_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.007433 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	1037	Shared Neighborhood Hits	31
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

THUM1_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.012491 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

TRIM5_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.003289 (rank : 187)
Query Neighborhood Hits	154	Target Neighborhood Hits	424	Shared Neighborhood Hits	37
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIPC_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.004504 (rank : 184)
Query Neighborhood Hits	154	Target Neighborhood Hits	319	Shared Neighborhood Hits	11
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

XRCC1_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.020758 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	242	Shared Neighborhood Hits	13
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ANR45_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.167143 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.125856 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

BPAEA_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.053791 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	1480	Shared Neighborhood Hits	94
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAF1A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.072440 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	750	Shared Neighborhood Hits	86
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.052804 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	736	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CALD1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.059720 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	90
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCD11_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.050733 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CENPF_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.053330 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	1932	Shared Neighborhood Hits	95
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF060_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.050217 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	1270	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CJ118_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.055282 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	1132	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

COVA1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.059432 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	416	Shared Neighborhood Hits	65
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CTGE5_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.054047 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	800	Shared Neighborhood Hits	79
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

EEA1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.055429 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	1796	Shared Neighborhood Hits	94
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FA44A_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051854 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	280	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

GOGA4_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.059365 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	1939	Shared Neighborhood Hits	100
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HOOK1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.057140 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	942	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HS12B_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.052045 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

IF2P_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.073631 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	889	Shared Neighborhood Hits	92
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.058199 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	875	Shared Neighborhood Hits	84
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IF3A_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.057851 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	871	Shared Neighborhood Hits	84
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.052312 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	939	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

KTN1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.051405 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	1197	Shared Neighborhood Hits	82
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LUZP1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.060339 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	739	Shared Neighborhood Hits	73
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.057782 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	940	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MAP9_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.055202 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	518	Shared Neighborhood Hits	72
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MAP9_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.054077 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	529	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MFAP1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.063002 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	321	Shared Neighborhood Hits	52
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MYH10_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.058857 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	1620	Shared Neighborhood Hits	96
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.058086 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	1612	Shared Neighborhood Hits	98
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RBM25_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.050183 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	682	Shared Neighborhood Hits	72
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RENT2_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.060058 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	618	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RPGR1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.057437 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	713	Shared Neighborhood Hits	83
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SFR12_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.070704 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	553	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.056969 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	486	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SMC1A_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.050117 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	1346	Shared Neighborhood Hits	90
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC4_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.051614 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

TAF7_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.050166 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TMF1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.051163 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	987	Shared Neighborhood Hits	83
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNNT2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.051891 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TRDN_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.065049 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	542	Shared Neighborhood Hits	69
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

TRHY_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.068898 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	1385	Shared Neighborhood Hits	96
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TRIPB_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.050612 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	1587	Shared Neighborhood Hits	98
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

Hits sorted by NC score

HSP74_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS105_MOUSE
NC score	0.984074 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_MOUSE
NC score	0.981192 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	44
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_MOUSE
NC score	0.980190 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	257	Shared Neighborhood Hits	98
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HS74L_HUMAN
NC score	0.979285 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_HUMAN
NC score	0.978457 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	209	Shared Neighborhood Hits	56
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS70L_MOUSE
NC score	0.903799 (rank : 7)	θ value	1.22964e-73 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	26
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP76_HUMAN
NC score	0.903790 (rank : 8)	θ value	3.12697e-77 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HS70L_HUMAN
NC score	0.903191 (rank : 9)	θ value	3.82246e-75 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

GRP75_MOUSE
NC score	0.902977 (rank : 10)	θ value	2.57589e-55 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HS70B_MOUSE
NC score	0.902604 (rank : 11)	θ value	1.45253e-74 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70A_MOUSE
NC score	0.902589 (rank : 12)	θ value	1.45253e-74 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	73	Shared Neighborhood Hits	33
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HSP71_HUMAN
NC score	0.902349 (rank : 13)	θ value	2.92676e-75 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

GRP75_HUMAN
NC score	0.901848 (rank : 14)	θ value	4.39379e-55 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	33
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

HSP7C_HUMAN
NC score	0.901046 (rank : 15)	θ value	3.23591e-74 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	48
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
NC score	0.900677 (rank : 16)	θ value	3.23591e-74 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	52
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP72_HUMAN
NC score	0.900012 (rank : 17)	θ value	4.09345e-69 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
NC score	0.899772 (rank : 18)	θ value	1.19101e-68 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

GRP78_MOUSE
NC score	0.897542 (rank : 19)	θ value	7.97034e-73 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	216	Shared Neighborhood Hits	58
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP78_HUMAN
NC score	0.897503 (rank : 20)	θ value	1.04096e-72 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	218	Shared Neighborhood Hits	59
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

OXRP_HUMAN
NC score	0.897057 (rank : 21)	θ value	2.64714e-76 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	544	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

STCH_HUMAN
NC score	0.895259 (rank : 22)	θ value	5.21438e-40 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
NC score	0.890749 (rank : 23)	θ value	8.32485e-38 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

ANR45_HUMAN
NC score	0.167143 (rank : 24)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
NC score	0.125856 (rank : 25)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
NC score	0.095804 (rank : 26)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

CCD91_HUMAN
NC score	0.081216 (rank : 27)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SYCP1_MOUSE
NC score	0.077015 (rank : 28)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	1456	Shared Neighborhood Hits	92
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ENKUR_MOUSE
NC score	0.073752 (rank : 29)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

IF2P_HUMAN
NC score	0.073631 (rank : 30)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	889	Shared Neighborhood Hits	92
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SYCP1_HUMAN
NC score	0.072915 (rank : 31)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	1313	Shared Neighborhood Hits	95
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CAF1A_HUMAN
NC score	0.072440 (rank : 32)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	750	Shared Neighborhood Hits	86
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SFR12_HUMAN
NC score	0.070704 (rank : 33)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	154	Target Neighborhood Hits	553	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

TRHY_HUMAN
NC score	0.068898 (rank : 34)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	154	Target Neighborhood Hits	1385	Shared Neighborhood Hits	96
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SMC3_MOUSE
NC score	0.068678 (rank : 35)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	1187	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.068591 (rank : 36)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	1186	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

FLIP1_HUMAN
NC score	0.066935 (rank : 37)	θ value	0.00175202 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	1405	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

HMMR_HUMAN
NC score	0.065429 (rank : 38)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

TRDN_HUMAN
NC score	0.065049 (rank : 39)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	154	Target Neighborhood Hits	542	Shared Neighborhood Hits	69
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

MFAP1_HUMAN
NC score	0.063002 (rank : 40)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	321	Shared Neighborhood Hits	52
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

GOGA4_HUMAN
NC score	0.062798 (rank : 41)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	2034	Shared Neighborhood Hits	102
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
NC score	0.061612 (rank : 42)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	2297	Shared Neighborhood Hits	114
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD91_MOUSE
NC score	0.061091 (rank : 43)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	699	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

REST_MOUSE
NC score	0.060816 (rank : 44)	θ value	0.0736092 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	1506	Shared Neighborhood Hits	93
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

FLIP1_MOUSE
NC score	0.060662 (rank : 45)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	1176	Shared Neighborhood Hits	89
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

BICD2_MOUSE
NC score	0.060547 (rank : 46)	θ value	0.0148317 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	864	Shared Neighborhood Hits	82
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

LUZP1_HUMAN
NC score	0.060339 (rank : 47)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	739	Shared Neighborhood Hits	73
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYH11_HUMAN
NC score	0.060096 (rank : 48)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	1806	Shared Neighborhood Hits	110
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RENT2_HUMAN
NC score	0.060058 (rank : 49)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	154	Target Neighborhood Hits	618	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

CALD1_HUMAN
NC score	0.059720 (rank : 50)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	90
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

COVA1_HUMAN
NC score	0.059432 (rank : 51)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	416	Shared Neighborhood Hits	65
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

GOGA4_MOUSE
NC score	0.059365 (rank : 52)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	1939	Shared Neighborhood Hits	100
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH10_HUMAN
NC score	0.058857 (rank : 53)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	1620	Shared Neighborhood Hits	96
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
NC score	0.058805 (rank : 54)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	1762	Shared Neighborhood Hits	107
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RBP24_HUMAN
NC score	0.058674 (rank : 55)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	1559	Shared Neighborhood Hits	91
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.058614 (rank : 56)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	1558	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
NC score	0.058449 (rank : 57)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IF3A_HUMAN
NC score	0.058199 (rank : 58)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	875	Shared Neighborhood Hits	84
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

MYH10_MOUSE
NC score	0.058086 (rank : 59)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	154	Target Neighborhood Hits	1612	Shared Neighborhood Hits	98
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

REST_HUMAN
NC score	0.058077 (rank : 60)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	1605	Shared Neighborhood Hits	98
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CCD11_HUMAN
NC score	0.058058 (rank : 61)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	822	Shared Neighborhood Hits	81
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IF3A_MOUSE
NC score	0.057851 (rank : 62)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	871	Shared Neighborhood Hits	84
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

LUZP1_MOUSE
NC score	0.057782 (rank : 63)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	940	Shared Neighborhood Hits	87
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

RPGR1_MOUSE
NC score	0.057437 (rank : 64)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	154	Target Neighborhood Hits	713	Shared Neighborhood Hits	83
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

HOOK1_HUMAN
NC score	0.057140 (rank : 65)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	942	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

SFR12_MOUSE
NC score	0.056969 (rank : 66)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	154	Target Neighborhood Hits	486	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

MYH9_MOUSE
NC score	0.055700 (rank : 67)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	1829	Shared Neighborhood Hits	108
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

EEA1_HUMAN
NC score	0.055429 (rank : 68)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	1796	Shared Neighborhood Hits	94
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CJ118_MOUSE
NC score	0.055282 (rank : 69)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	1132	Shared Neighborhood Hits	80
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

MYH11_MOUSE
NC score	0.055208 (rank : 70)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	1777	Shared Neighborhood Hits	104
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MAP9_HUMAN
NC score	0.055202 (rank : 71)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	518	Shared Neighborhood Hits	72
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

RAD50_HUMAN
NC score	0.055102 (rank : 72)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	1317	Shared Neighborhood Hits	87
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CENPE_HUMAN
NC score	0.054998 (rank : 73)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	2060	Shared Neighborhood Hits	102
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MAP9_MOUSE
NC score	0.054077 (rank : 74)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	529	Shared Neighborhood Hits	70
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CTGE5_HUMAN
NC score	0.054047 (rank : 75)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	800	Shared Neighborhood Hits	79
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

MAP1A_HUMAN
NC score	0.054028 (rank : 76)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	1626	Shared Neighborhood Hits	98
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

BPAEA_MOUSE
NC score	0.053791 (rank : 77)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	1480	Shared Neighborhood Hits	94
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD46_MOUSE
NC score	0.053508 (rank : 78)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	1405	Shared Neighborhood Hits	93
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CENPF_HUMAN
NC score	0.053330 (rank : 79)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	1932	Shared Neighborhood Hits	95
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CAF1A_MOUSE
NC score	0.052804 (rank : 80)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	736	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

INVO_MOUSE
NC score	0.052758 (rank : 81)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	474	Shared Neighborhood Hits	61
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

BICD2_HUMAN
NC score	0.052691 (rank : 82)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	856	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

IFT74_MOUSE
NC score	0.052312 (rank : 83)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	939	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

HMMR_MOUSE
NC score	0.052259 (rank : 84)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	1178	Shared Neighborhood Hits	85
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA5_HUMAN
NC score	0.052255 (rank : 85)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	1168	Shared Neighborhood Hits	91
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

BPAEA_HUMAN
NC score	0.052071 (rank : 86)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	1369	Shared Neighborhood Hits	85
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HS12B_HUMAN
NC score	0.052045 (rank : 87)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

BRE1A_HUMAN
NC score	0.051983 (rank : 88)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	1071	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

TNNT2_HUMAN
NC score	0.051891 (rank : 89)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	154	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

CCD46_HUMAN
NC score	0.051860 (rank : 90)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	1430	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

FA44A_HUMAN
NC score	0.051854 (rank : 91)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	280	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

SMC4_HUMAN
NC score	0.051614 (rank : 92)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

KTN1_HUMAN
NC score	0.051405 (rank : 93)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	1197	Shared Neighborhood Hits	82
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

RAD50_MOUSE
NC score	0.051293 (rank : 94)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	1366	Shared Neighborhood Hits	87
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TMF1_HUMAN
NC score	0.051163 (rank : 95)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	154	Target Neighborhood Hits	987	Shared Neighborhood Hits	83
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

CCD11_MOUSE
NC score	0.050733 (rank : 96)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	498	Shared Neighborhood Hits	69
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

TRIPB_HUMAN
NC score	0.050612 (rank : 97)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	154	Target Neighborhood Hits	1587	Shared Neighborhood Hits	98
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CCD62_HUMAN
NC score	0.050576 (rank : 98)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	631	Shared Neighborhood Hits	71
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

RBCC1_HUMAN
NC score	0.050295 (rank : 99)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	1023	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CF060_HUMAN
NC score	0.050217 (rank : 100)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	1270	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

RBM25_HUMAN
NC score	0.050183 (rank : 101)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	154	Target Neighborhood Hits	682	Shared Neighborhood Hits	72
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TAF7_MOUSE
NC score	0.050166 (rank : 102)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	154	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

SMC1A_HUMAN
NC score	0.050117 (rank : 103)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	154	Target Neighborhood Hits	1346	Shared Neighborhood Hits	90
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

KIF23_HUMAN
NC score	0.049767 (rank : 104)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	618	Shared Neighborhood Hits	70
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

BPA1_MOUSE
NC score	0.049643 (rank : 105)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	1477	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CJ118_HUMAN
NC score	0.048964 (rank : 106)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	937	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

LIPA2_MOUSE
NC score	0.048712 (rank : 107)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	1282	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

PLCB4_HUMAN
NC score	0.048484 (rank : 108)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	658	Shared Neighborhood Hits	72
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

AKAP2_MOUSE
NC score	0.048034 (rank : 109)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CYLN2_HUMAN
NC score	0.048011 (rank : 110)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	1004	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLC1_HUMAN
NC score	0.047762 (rank : 111)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	408	Shared Neighborhood Hits	48
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

IFT74_HUMAN
NC score	0.047476 (rank : 112)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	949	Shared Neighborhood Hits	77
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

LRC45_MOUSE
NC score	0.047347 (rank : 113)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	77
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CTGE2_HUMAN
NC score	0.047155 (rank : 114)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	594	Shared Neighborhood Hits	72
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

EEA1_MOUSE
NC score	0.046350 (rank : 115)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	1637	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CP250_MOUSE
NC score	0.046271 (rank : 116)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	1583	Shared Neighborhood Hits	89
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

SPRL1_MOUSE
NC score	0.045714 (rank : 117)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

LEO1_HUMAN
NC score	0.045713 (rank : 118)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MYO5B_HUMAN
NC score	0.045535 (rank : 119)	θ value	0.000602161 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	911	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

CR034_HUMAN
NC score	0.045500 (rank : 120)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	538	Shared Neighborhood Hits	64
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CI093_HUMAN
NC score	0.045436 (rank : 121)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	1088	Shared Neighborhood Hits	82
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CJ068_HUMAN
NC score	0.045304 (rank : 122)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	316	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

GCC1_MOUSE
NC score	0.045144 (rank : 123)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	777	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

KTN1_MOUSE
NC score	0.045083 (rank : 124)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	1324	Shared Neighborhood Hits	87
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

DEK_MOUSE
NC score	0.044664 (rank : 125)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	280	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

CCD41_MOUSE
NC score	0.042557 (rank : 126)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

DYHC_HUMAN
NC score	0.042307 (rank : 127)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	733	Shared Neighborhood Hits	71
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.042277 (rank : 128)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	729	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

SMCE1_MOUSE
NC score	0.042269 (rank : 129)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	409	Shared Neighborhood Hits	49
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

PCNT_HUMAN
NC score	0.042260 (rank : 130)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	1551	Shared Neighborhood Hits	85
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

KI21B_HUMAN
NC score	0.042032 (rank : 131)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	1017	Shared Neighborhood Hits	83
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

CK5P2_MOUSE
NC score	0.042030 (rank : 132)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	1151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

K0256_HUMAN
NC score	0.041224 (rank : 133)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

GOGA5_MOUSE
NC score	0.041128 (rank : 134)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	1434	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

MY18A_HUMAN
NC score	0.041033 (rank : 135)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	1929	Shared Neighborhood Hits	100
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH3_HUMAN
NC score	0.040967 (rank : 136)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	1660	Shared Neighborhood Hits	97
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MACF1_MOUSE
NC score	0.040465 (rank : 137)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	1313	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MYO5C_HUMAN
NC score	0.040199 (rank : 138)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	1206	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RUFY2_HUMAN
NC score	0.039859 (rank : 139)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	1208	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

ANR26_HUMAN
NC score	0.039701 (rank : 140)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	1614	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

RAI14_MOUSE
NC score	0.039450 (rank : 141)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	1505	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

KIF3A_HUMAN
NC score	0.039398 (rank : 142)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	704	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

PCIF1_HUMAN
NC score	0.039356 (rank : 143)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

TTF1_MOUSE
NC score	0.039239 (rank : 144)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	277	Shared Neighborhood Hits	25
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

KIF3A_MOUSE
NC score	0.037801 (rank : 145)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	715	Shared Neighborhood Hits	77
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

IWS1_MOUSE
NC score	0.036825 (rank : 146)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	1258	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RYR1_HUMAN
NC score	0.036597 (rank : 147)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	303	Shared Neighborhood Hits	29
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

GP73_MOUSE
NC score	0.035881 (rank : 148)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	506	Shared Neighborhood Hits	69
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

HOME2_HUMAN
NC score	0.035068 (rank : 149)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	532	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

SPTB2_MOUSE
NC score	0.034345 (rank : 150)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	770	Shared Neighborhood Hits	75
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MOES_MOUSE
NC score	0.033449 (rank : 151)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	923	Shared Neighborhood Hits	80
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

IWS1_HUMAN
NC score	0.032426 (rank : 152)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	1241	Shared Neighborhood Hits	60
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_MOUSE
NC score	0.032083 (rank : 153)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	43
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

DAXX_HUMAN
NC score	0.031774 (rank : 154)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

CJ078_MOUSE
NC score	0.028970 (rank : 155)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	559	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MRCKA_HUMAN
NC score	0.027177 (rank : 156)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	1999	Shared Neighborhood Hits	85
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PPIG_HUMAN
NC score	0.024573 (rank : 157)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	670	Shared Neighborhood Hits	66
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

XRCC1_MOUSE
NC score	0.020758 (rank : 158)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	242	Shared Neighborhood Hits	13
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

RBBP6_HUMAN
NC score	0.020311 (rank : 159)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

DMN_HUMAN
NC score	0.020296 (rank : 160)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	690	Shared Neighborhood Hits	61
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

STK10_MOUSE
NC score	0.019118 (rank : 161)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	2132	Shared Neighborhood Hits	92
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

FEZ2_MOUSE
NC score	0.018333 (rank : 162)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

FEZ2_HUMAN
NC score	0.017039 (rank : 163)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UHY8, Q76LN0, Q99690	Gene names	FEZ2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

UBP10_MOUSE
NC score	0.016758 (rank : 164)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	150	Shared Neighborhood Hits	8
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

DDX46_MOUSE
NC score	0.016252 (rank : 165)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	358	Shared Neighborhood Hits	49
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX46_HUMAN
NC score	0.015876 (rank : 166)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	357	Shared Neighborhood Hits	49
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

DOPO_HUMAN
NC score	0.015832 (rank : 167)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P09172, Q5T381, Q96AG2	Gene names	DBH
Domain Architecture
Description	Dopamine beta-hydroxylase precursor (EC 1.14.17.1) (Dopamine beta- monooxygenase).

NCKX1_HUMAN
NC score	0.014299 (rank : 168)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ALMS1_HUMAN
NC score	0.014080 (rank : 169)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ADA30_HUMAN
NC score	0.012519 (rank : 170)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	391	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

THUM1_MOUSE
NC score	0.012491 (rank : 171)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q99J36, Q3U6Y3	Gene names	Thumpd1
Domain Architecture
Description	THUMP domain-containing protein 1.

TITIN_HUMAN
NC score	0.011360 (rank : 172)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	2923	Shared Neighborhood Hits	78
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DLEC1_HUMAN
NC score	0.010820 (rank : 173)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

FACD2_HUMAN
NC score	0.010550 (rank : 174)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXW9, Q2LA86, Q69YP9, Q6PJN7, Q9BQ06, Q9H9T9	Gene names	FANCD2
Domain Architecture	No domain graphic available
Description	Fanconi anemia group D2 protein (Protein FACD2).

RAD_HUMAN
NC score	0.008644 (rank : 175)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).

SMCA2_HUMAN
NC score	0.007485 (rank : 176)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RPTN_MOUSE
NC score	0.007456 (rank : 177)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	650	Shared Neighborhood Hits	32
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

TGON2_HUMAN
NC score	0.007433 (rank : 178)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	1037	Shared Neighborhood Hits	31
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RAD_MOUSE
NC score	0.006803 (rank : 179)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	O88667	Gene names	Rrad
Domain Architecture
Description	GTP-binding protein RAD.

OTOF_MOUSE
NC score	0.006285 (rank : 180)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

ANK3_HUMAN
NC score	0.005585 (rank : 181)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	853	Shared Neighborhood Hits	40
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

RTEL1_HUMAN
NC score	0.004680 (rank : 182)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ71, Q5JTV4, Q9BW37, Q9H402, Q9H4X6, Q9NX25, Q9NZ73, Q9UPR4, Q9Y4R6	Gene names	RTEL1, C20orf41, KIAA1088, NHL
Domain Architecture
Description	Regulator of telomere elongation helicase 1 (EC 3.6.1.-) (Helicase- like protein NHL).

PRLPK_MOUSE
NC score	0.004600 (rank : 183)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAZ2, Q2TA52	Gene names	Prlpk
Domain Architecture	No domain graphic available
Description	Placental prolactin-like protein K precursor (PRL-like protein K) (PLP-K).

TRIPC_HUMAN
NC score	0.004504 (rank : 184)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	319	Shared Neighborhood Hits	11
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

RFFL_HUMAN
NC score	0.004273 (rank : 185)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

DDX21_MOUSE
NC score	0.003749 (rank : 186)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

TRIM5_HUMAN
NC score	0.003289 (rank : 187)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	424	Shared Neighborhood Hits	37
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

NACAM_MOUSE
NC score	0.003119 (rank : 188)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

REM1_MOUSE
NC score	0.002079 (rank : 189)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	255	Shared Neighborhood Hits	4
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

PEG3_MOUSE
NC score	0.001554 (rank : 190)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	1101	Shared Neighborhood Hits	26
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

IRAK1_MOUSE
NC score	0.000462 (rank : 191)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

EGR3_HUMAN
NC score	-0.000568 (rank : 192)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	746	Shared Neighborhood Hits	7
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

SLIT3_MOUSE
NC score	-0.000603 (rank : 193)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	700	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EGR3_MOUSE
NC score	-0.000825 (rank : 194)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	747	Shared Neighborhood Hits	7
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

ZN710_MOUSE
NC score	-0.003479 (rank : 195)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

ZNF18_HUMAN
NC score	-0.003483 (rank : 196)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	748	Shared Neighborhood Hits	6
SwissProt Accessions	P17022, Q5QHQ3, Q8IYC4, Q8NAH6	Gene names	ZNF18, HDSG1, KOX11
Domain Architecture	No domain graphic available
Description	Zinc finger protein 18 (Zinc finger protein KOX11) (Heart development- specific gene 1 protein).