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Network neighborhood for query Sequence : HSP76_HUMAN

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HSP76_HUMAN
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRP78_HUMAN
θ value	0 (rank : 1)	NC score	0.982771 (rank : 11)
Query Neighborhood Hits	128	Target Neighborhood Hits	218	Shared Neighborhood Hits	66
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	0 (rank : 2)	NC score	0.982759 (rank : 12)
Query Neighborhood Hits	128	Target Neighborhood Hits	216	Shared Neighborhood Hits	67
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

HS70A_MOUSE
θ value	0 (rank : 3)	NC score	0.994840 (rank : 4)
Query Neighborhood Hits	128	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	0 (rank : 4)	NC score	0.994867 (rank : 3)
Query Neighborhood Hits	128	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70L_HUMAN
θ value	0 (rank : 5)	NC score	0.994075 (rank : 6)
Query Neighborhood Hits	128	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70L_MOUSE
θ value	0 (rank : 6)	NC score	0.994269 (rank : 5)
Query Neighborhood Hits	128	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP71_HUMAN
θ value	0 (rank : 7)	NC score	0.995220 (rank : 2)
Query Neighborhood Hits	128	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HSP72_HUMAN
θ value	0 (rank : 8)	NC score	0.993665 (rank : 8)
Query Neighborhood Hits	128	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
θ value	0 (rank : 9)	NC score	0.993691 (rank : 7)
Query Neighborhood Hits	128	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP76_HUMAN
θ value	0 (rank : 10)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	128	Target Neighborhood Hits	128	Shared Neighborhood Hits	128
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
θ value	0 (rank : 11)	NC score	0.992562 (rank : 9)
Query Neighborhood Hits	128	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	0 (rank : 12)	NC score	0.991899 (rank : 10)
Query Neighborhood Hits	128	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP75_MOUSE
θ value	3.16907e-146 (rank : 13)	NC score	0.982411 (rank : 13)
Query Neighborhood Hits	128	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
θ value	1.20424e-145 (rank : 14)	NC score	0.981934 (rank : 14)
Query Neighborhood Hits	128	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

HSP74_MOUSE
θ value	2.82823e-78 (rank : 15)	NC score	0.893511 (rank : 22)
Query Neighborhood Hits	128	Target Neighborhood Hits	257	Shared Neighborhood Hits	50
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HSP74_HUMAN
θ value	3.12697e-77 (rank : 16)	NC score	0.903790 (rank : 19)
Query Neighborhood Hits	128	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

STCH_HUMAN
θ value	6.52014e-75 (rank : 17)	NC score	0.963609 (rank : 15)
Query Neighborhood Hits	128	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
θ value	3.23591e-74 (rank : 18)	NC score	0.963139 (rank : 16)
Query Neighborhood Hits	128	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS74L_MOUSE
θ value	7.20884e-74 (rank : 19)	NC score	0.904364 (rank : 18)
Query Neighborhood Hits	128	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_HUMAN
θ value	1.35953e-72 (rank : 20)	NC score	0.903248 (rank : 20)
Query Neighborhood Hits	128	Target Neighborhood Hits	141	Shared Neighborhood Hits	43
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_HUMAN
θ value	1.96316e-71 (rank : 21)	NC score	0.900225 (rank : 21)
Query Neighborhood Hits	128	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	3.34864e-71 (rank : 22)	NC score	0.906977 (rank : 17)
Query Neighborhood Hits	128	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

OXRP_HUMAN
θ value	2.84797e-54 (rank : 23)	NC score	0.877027 (rank : 23)
Query Neighborhood Hits	128	Target Neighborhood Hits	544	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

MYH14_HUMAN
θ value	0.0193708 (rank : 24)	NC score	0.042742 (rank : 43)
Query Neighborhood Hits	128	Target Neighborhood Hits	995	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH11_HUMAN
θ value	0.0431538 (rank : 25)	NC score	0.058048 (rank : 31)
Query Neighborhood Hits	128	Target Neighborhood Hits	1806	Shared Neighborhood Hits	107
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	0.0431538 (rank : 26)	NC score	0.050723 (rank : 38)
Query Neighborhood Hits	128	Target Neighborhood Hits	1777	Shared Neighborhood Hits	97
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH10_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.052906 (rank : 33)
Query Neighborhood Hits	128	Target Neighborhood Hits	1620	Shared Neighborhood Hits	97
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.052622 (rank : 35)
Query Neighborhood Hits	128	Target Neighborhood Hits	1612	Shared Neighborhood Hits	97
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

ANR45_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.240748 (rank : 24)
Query Neighborhood Hits	128	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.137134 (rank : 26)
Query Neighborhood Hits	128	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

TRHY_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.032254 (rank : 66)
Query Neighborhood Hits	128	Target Neighborhood Hits	1385	Shared Neighborhood Hits	63
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ITSN2_MOUSE
θ value	0.0961366 (rank : 32)	NC score	0.023304 (rank : 97)
Query Neighborhood Hits	128	Target Neighborhood Hits	1371	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MYO6_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.039653 (rank : 50)
Query Neighborhood Hits	128	Target Neighborhood Hits	727	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

SFR12_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.070422 (rank : 28)
Query Neighborhood Hits	128	Target Neighborhood Hits	553	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

CAF1A_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.065900 (rank : 29)
Query Neighborhood Hits	128	Target Neighborhood Hits	750	Shared Neighborhood Hits	50
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

INCE_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.025031 (rank : 90)
Query Neighborhood Hits	128	Target Neighborhood Hits	978	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

PWP1_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.018898 (rank : 106)
Query Neighborhood Hits	128	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

SLK_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.007704 (rank : 123)
Query Neighborhood Hits	128	Target Neighborhood Hits	1798	Shared Neighborhood Hits	86
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

MYO6_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.036475 (rank : 56)
Query Neighborhood Hits	128	Target Neighborhood Hits	586	Shared Neighborhood Hits	48
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

PWP1_HUMAN
θ value	0.21417 (rank : 40)	NC score	0.014916 (rank : 113)
Query Neighborhood Hits	128	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

ANR38_MOUSE
θ value	0.279714 (rank : 41)	NC score	0.015332 (rank : 112)
Query Neighborhood Hits	128	Target Neighborhood Hits	512	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

SLK_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.006307 (rank : 124)
Query Neighborhood Hits	128	Target Neighborhood Hits	1775	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

ANR45_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.183071 (rank : 25)
Query Neighborhood Hits	128	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

CCD43_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.031482 (rank : 69)
Query Neighborhood Hits	128	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

GOGB1_HUMAN
θ value	0.47712 (rank : 45)	NC score	0.046917 (rank : 41)
Query Neighborhood Hits	128	Target Neighborhood Hits	2297	Shared Neighborhood Hits	101
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HS12B_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.083208 (rank : 27)
Query Neighborhood Hits	128	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

MYH9_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.051294 (rank : 36)
Query Neighborhood Hits	128	Target Neighborhood Hits	1829	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPR_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.027483 (rank : 82)
Query Neighborhood Hits	128	Target Neighborhood Hits	1921	Shared Neighborhood Hits	91
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

FLNA_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.034082 (rank : 61)
Query Neighborhood Hits	128	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

K2C4_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.013207 (rank : 115)
Query Neighborhood Hits	128	Target Neighborhood Hits	521	Shared Neighborhood Hits	47
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

HOOK2_MOUSE
θ value	0.813845 (rank : 51)	NC score	0.020647 (rank : 104)
Query Neighborhood Hits	128	Target Neighborhood Hits	736	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

MYH9_HUMAN
θ value	0.813845 (rank : 52)	NC score	0.052673 (rank : 34)
Query Neighborhood Hits	128	Target Neighborhood Hits	1762	Shared Neighborhood Hits	104
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NFM_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.026182 (rank : 87)
Query Neighborhood Hits	128	Target Neighborhood Hits	1328	Shared Neighborhood Hits	70
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

CCD43_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.029475 (rank : 75)
Query Neighborhood Hits	128	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CR29, Q6PDT2	Gene names	Ccdc43, D11Ertd707e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

GCP60_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.024115 (rank : 94)
Query Neighborhood Hits	128	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

U2AFM_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.041139 (rank : 46)
Query Neighborhood Hits	128	Target Neighborhood Hits	577	Shared Neighborhood Hits	48
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

U2AFM_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.027333 (rank : 83)
Query Neighborhood Hits	128	Target Neighborhood Hits	543	Shared Neighborhood Hits	47
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

BPAEA_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.039868 (rank : 49)
Query Neighborhood Hits	128	Target Neighborhood Hits	1480	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CHCH3_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.027654 (rank : 80)
Query Neighborhood Hits	128	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

GCP60_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.025330 (rank : 89)
Query Neighborhood Hits	128	Target Neighborhood Hits	395	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

INCE_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.022877 (rank : 99)
Query Neighborhood Hits	128	Target Neighborhood Hits	903	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MYO7A_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.028445 (rank : 78)
Query Neighborhood Hits	128	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

BRE1B_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.031871 (rank : 68)
Query Neighborhood Hits	128	Target Neighborhood Hits	970	Shared Neighborhood Hits	74
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

FLNA_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.029589 (rank : 74)
Query Neighborhood Hits	128	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

MAP1B_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.023422 (rank : 96)
Query Neighborhood Hits	128	Target Neighborhood Hits	977	Shared Neighborhood Hits	37
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RPGR1_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.036928 (rank : 55)
Query Neighborhood Hits	128	Target Neighborhood Hits	713	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SAFB2_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.012353 (rank : 117)
Query Neighborhood Hits	128	Target Neighborhood Hits	581	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SMC4_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.023830 (rank : 95)
Query Neighborhood Hits	128	Target Neighborhood Hits	830	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

BRE1B_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.032732 (rank : 65)
Query Neighborhood Hits	128	Target Neighborhood Hits	1040	Shared Neighborhood Hits	79
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MAP9_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.047277 (rank : 40)
Query Neighborhood Hits	128	Target Neighborhood Hits	529	Shared Neighborhood Hits	43
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYH6_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.040892 (rank : 47)
Query Neighborhood Hits	128	Target Neighborhood Hits	1501	Shared Neighborhood Hits	92
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TNIP3_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.025927 (rank : 88)
Query Neighborhood Hits	128	Target Neighborhood Hits	511	Shared Neighborhood Hits	59
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

U2AFL_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.030109 (rank : 73)
Query Neighborhood Hits	128	Target Neighborhood Hits	503	Shared Neighborhood Hits	46
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

CROCC_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.027567 (rank : 81)
Query Neighborhood Hits	128	Target Neighborhood Hits	1409	Shared Neighborhood Hits	79
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

M4K4_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.004328 (rank : 125)
Query Neighborhood Hits	128	Target Neighborhood Hits	1589	Shared Neighborhood Hits	54
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NEMO_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.022635 (rank : 100)
Query Neighborhood Hits	128	Target Neighborhood Hits	658	Shared Neighborhood Hits	62
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TAF7_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.035026 (rank : 59)
Query Neighborhood Hits	128	Target Neighborhood Hits	222	Shared Neighborhood Hits	28
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TAF7_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.038573 (rank : 51)
Query Neighborhood Hits	128	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TMF1_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.027032 (rank : 84)
Query Neighborhood Hits	128	Target Neighborhood Hits	987	Shared Neighborhood Hits	74
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

AZI1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.021443 (rank : 103)
Query Neighborhood Hits	128	Target Neighborhood Hits	990	Shared Neighborhood Hits	82
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BSN_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.008314 (rank : 122)
Query Neighborhood Hits	128	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MAP1A_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.035189 (rank : 58)
Query Neighborhood Hits	128	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYH8_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.036987 (rank : 54)
Query Neighborhood Hits	128	Target Neighborhood Hits	1610	Shared Neighborhood Hits	94
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NUMA1_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.021876 (rank : 102)
Query Neighborhood Hits	128	Target Neighborhood Hits	1523	Shared Neighborhood Hits	84
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

RENT2_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.033697 (rank : 63)
Query Neighborhood Hits	128	Target Neighborhood Hits	618	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SRCH_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.020100 (rank : 105)
Query Neighborhood Hits	128	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TESK2_MOUSE
θ value	4.03905 (rank : 87)	NC score	-0.002251 (rank : 129)
Query Neighborhood Hits	128	Target Neighborhood Hits	833	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TSC1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.022545 (rank : 101)
Query Neighborhood Hits	128	Target Neighborhood Hits	765	Shared Neighborhood Hits	61
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

CALD1_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.028662 (rank : 77)
Query Neighborhood Hits	128	Target Neighborhood Hits	959	Shared Neighborhood Hits	66
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

ITSN2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.011519 (rank : 118)
Query Neighborhood Hits	128	Target Neighborhood Hits	1173	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KIF4A_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.015453 (rank : 111)
Query Neighborhood Hits	128	Target Neighborhood Hits	1033	Shared Neighborhood Hits	80
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MACF1_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.024870 (rank : 91)
Query Neighborhood Hits	128	Target Neighborhood Hits	1341	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

REST_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.034380 (rank : 60)
Query Neighborhood Hits	128	Target Neighborhood Hits	1506	Shared Neighborhood Hits	86
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RFIP4_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.029113 (rank : 76)
Query Neighborhood Hits	128	Target Neighborhood Hits	785	Shared Neighborhood Hits	74
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SMC4_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.032115 (rank : 67)
Query Neighborhood Hits	128	Target Neighborhood Hits	937	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

TNNT2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.033264 (rank : 64)
Query Neighborhood Hits	128	Target Neighborhood Hits	433	Shared Neighborhood Hits	47
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

VPS35_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.011327 (rank : 120)
Query Neighborhood Hits	128	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QK1, Q561W2, Q9H016, Q9H096, Q9H4P3, Q9H8J0, Q9NRS7, Q9NVG2, Q9NX80, Q9NZK2	Gene names	VPS35, MEM3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (hVPS35) (Maternal-embryonic 3).

VPS35_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.011327 (rank : 119)
Query Neighborhood Hits	128	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQH3, Q61123	Gene names	Vps35, Mem3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (Maternal-embryonic 3).

XE7_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.026631 (rank : 86)
Query Neighborhood Hits	128	Target Neighborhood Hits	738	Shared Neighborhood Hits	54
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ANR12_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.015518 (rank : 110)
Query Neighborhood Hits	128	Target Neighborhood Hits	1081	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

BAZ2A_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.016962 (rank : 109)
Query Neighborhood Hits	128	Target Neighborhood Hits	780	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BSN_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.010652 (rank : 121)
Query Neighborhood Hits	128	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

COVA1_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.055976 (rank : 32)
Query Neighborhood Hits	128	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CP250_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.028426 (rank : 79)
Query Neighborhood Hits	128	Target Neighborhood Hits	1583	Shared Neighborhood Hits	87
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

FLNB_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.013560 (rank : 114)
Query Neighborhood Hits	128	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

FLNB_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.012548 (rank : 116)
Query Neighborhood Hits	128	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

IF2P_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.046334 (rank : 42)
Query Neighborhood Hits	128	Target Neighborhood Hits	889	Shared Neighborhood Hits	52
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MACF1_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.024812 (rank : 92)
Query Neighborhood Hits	128	Target Neighborhood Hits	1313	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MAP9_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.041248 (rank : 45)
Query Neighborhood Hits	128	Target Neighborhood Hits	518	Shared Neighborhood Hits	42
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYH14_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.042302 (rank : 44)
Query Neighborhood Hits	128	Target Neighborhood Hits	1225	Shared Neighborhood Hits	85
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH4_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.037014 (rank : 53)
Query Neighborhood Hits	128	Target Neighborhood Hits	1476	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.037609 (rank : 52)
Query Neighborhood Hits	128	Target Neighborhood Hits	1426	Shared Neighborhood Hits	86
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.040100 (rank : 48)
Query Neighborhood Hits	128	Target Neighborhood Hits	1600	Shared Neighborhood Hits	94
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NIN_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.031033 (rank : 71)
Query Neighborhood Hits	128	Target Neighborhood Hits	1416	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PELP1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.026697 (rank : 85)
Query Neighborhood Hits	128	Target Neighborhood Hits	596	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RFIP4_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.022923 (rank : 98)
Query Neighborhood Hits	128	Target Neighborhood Hits	708	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

SFR12_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.058652 (rank : 30)
Query Neighborhood Hits	128	Target Neighborhood Hits	486	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SYWM_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.035866 (rank : 57)
Query Neighborhood Hits	128	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CYK1	Gene names	Wars2
Domain Architecture
Description	Tryptophanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) ((Mt)TrpRS).

CCD46_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.030362 (rank : 72)
Query Neighborhood Hits	128	Target Neighborhood Hits	1430	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DYXC1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.048543 (rank : 39)
Query Neighborhood Hits	128	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

M4K4_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.003232 (rank : 126)
Query Neighborhood Hits	128	Target Neighborhood Hits	1560	Shared Neighborhood Hits	52
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.001210 (rank : 128)
Query Neighborhood Hits	128	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.001602 (rank : 127)
Query Neighborhood Hits	128	Target Neighborhood Hits	1451	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NFM_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.018265 (rank : 107)
Query Neighborhood Hits	128	Target Neighborhood Hits	1159	Shared Neighborhood Hits	70
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PININ_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.024126 (rank : 93)
Query Neighborhood Hits	128	Target Neighborhood Hits	777	Shared Neighborhood Hits	68
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PLEC1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.017607 (rank : 108)
Query Neighborhood Hits	128	Target Neighborhood Hits	1326	Shared Neighborhood Hits	66
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

UBXD2_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.034002 (rank : 62)
Query Neighborhood Hits	128	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

UBXD2_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.031077 (rank : 70)
Query Neighborhood Hits	128	Target Neighborhood Hits	183	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

FA44A_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.050848 (rank : 37)
Query Neighborhood Hits	128	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

Hits sorted by NC score

HSP76_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 10)
Query Neighborhood Hits	128	Target Neighborhood Hits	128	Shared Neighborhood Hits	128
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP71_HUMAN
NC score	0.995220 (rank : 2)	θ value	0 (rank : 7)
Query Neighborhood Hits	128	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70B_MOUSE
NC score	0.994867 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	128	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70A_MOUSE
NC score	0.994840 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	128	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70L_MOUSE
NC score	0.994269 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	128	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HS70L_HUMAN
NC score	0.994075 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	128	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HSP72_MOUSE
NC score	0.993691 (rank : 7)	θ value	0 (rank : 9)
Query Neighborhood Hits	128	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP72_HUMAN
NC score	0.993665 (rank : 8)	θ value	0 (rank : 8)
Query Neighborhood Hits	128	Target Neighborhood Hits	85	Shared Neighborhood Hits	46
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP7C_HUMAN
NC score	0.992562 (rank : 9)	θ value	0 (rank : 11)
Query Neighborhood Hits	128	Target Neighborhood Hits	150	Shared Neighborhood Hits	67
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
NC score	0.991899 (rank : 10)	θ value	0 (rank : 12)
Query Neighborhood Hits	128	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP78_HUMAN
NC score	0.982771 (rank : 11)	θ value	0 (rank : 1)
Query Neighborhood Hits	128	Target Neighborhood Hits	218	Shared Neighborhood Hits	66
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.982759 (rank : 12)	θ value	0 (rank : 2)
Query Neighborhood Hits	128	Target Neighborhood Hits	216	Shared Neighborhood Hits	67
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP75_MOUSE
NC score	0.982411 (rank : 13)	θ value	3.16907e-146 (rank : 13)
Query Neighborhood Hits	128	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
NC score	0.981934 (rank : 14)	θ value	1.20424e-145 (rank : 14)
Query Neighborhood Hits	128	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

STCH_HUMAN
NC score	0.963609 (rank : 15)	θ value	6.52014e-75 (rank : 17)
Query Neighborhood Hits	128	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
NC score	0.963139 (rank : 16)	θ value	3.23591e-74 (rank : 18)
Query Neighborhood Hits	128	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS105_MOUSE
NC score	0.906977 (rank : 17)	θ value	3.34864e-71 (rank : 22)
Query Neighborhood Hits	128	Target Neighborhood Hits	129	Shared Neighborhood Hits	33
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_MOUSE
NC score	0.904364 (rank : 18)	θ value	7.20884e-74 (rank : 19)
Query Neighborhood Hits	128	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
NC score	0.903790 (rank : 19)	θ value	3.12697e-77 (rank : 16)
Query Neighborhood Hits	128	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS74L_HUMAN
NC score	0.903248 (rank : 20)	θ value	1.35953e-72 (rank : 20)
Query Neighborhood Hits	128	Target Neighborhood Hits	141	Shared Neighborhood Hits	43
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_HUMAN
NC score	0.900225 (rank : 21)	θ value	1.96316e-71 (rank : 21)
Query Neighborhood Hits	128	Target Neighborhood Hits	209	Shared Neighborhood Hits	36
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HSP74_MOUSE
NC score	0.893511 (rank : 22)	θ value	2.82823e-78 (rank : 15)
Query Neighborhood Hits	128	Target Neighborhood Hits	257	Shared Neighborhood Hits	50
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

OXRP_HUMAN
NC score	0.877027 (rank : 23)	θ value	2.84797e-54 (rank : 23)
Query Neighborhood Hits	128	Target Neighborhood Hits	544	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ANR45_HUMAN
NC score	0.240748 (rank : 24)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	128	Target Neighborhood Hits	201	Shared Neighborhood Hits	15
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
NC score	0.183071 (rank : 25)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	128	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
NC score	0.137134 (rank : 26)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	128	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS12B_HUMAN
NC score	0.083208 (rank : 27)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	128	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

SFR12_HUMAN
NC score	0.070422 (rank : 28)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	128	Target Neighborhood Hits	553	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

CAF1A_HUMAN
NC score	0.065900 (rank : 29)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	128	Target Neighborhood Hits	750	Shared Neighborhood Hits	50
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SFR12_MOUSE
NC score	0.058652 (rank : 30)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	128	Target Neighborhood Hits	486	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

MYH11_HUMAN
NC score	0.058048 (rank : 31)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	128	Target Neighborhood Hits	1806	Shared Neighborhood Hits	107
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

COVA1_HUMAN
NC score	0.055976 (rank : 32)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	128	Target Neighborhood Hits	416	Shared Neighborhood Hits	38
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

MYH10_HUMAN
NC score	0.052906 (rank : 33)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	128	Target Neighborhood Hits	1620	Shared Neighborhood Hits	97
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
NC score	0.052673 (rank : 34)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	128	Target Neighborhood Hits	1762	Shared Neighborhood Hits	104
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH10_MOUSE
NC score	0.052622 (rank : 35)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	128	Target Neighborhood Hits	1612	Shared Neighborhood Hits	97
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_MOUSE
NC score	0.051294 (rank : 36)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	128	Target Neighborhood Hits	1829	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

FA44A_HUMAN
NC score	0.050848 (rank : 37)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	128	Target Neighborhood Hits	280	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MYH11_MOUSE
NC score	0.050723 (rank : 38)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	128	Target Neighborhood Hits	1777	Shared Neighborhood Hits	97
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

DYXC1_HUMAN
NC score	0.048543 (rank : 39)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	128	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

MAP9_MOUSE
NC score	0.047277 (rank : 40)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	128	Target Neighborhood Hits	529	Shared Neighborhood Hits	43
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

GOGB1_HUMAN
NC score	0.046917 (rank : 41)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	128	Target Neighborhood Hits	2297	Shared Neighborhood Hits	101
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IF2P_HUMAN
NC score	0.046334 (rank : 42)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	128	Target Neighborhood Hits	889	Shared Neighborhood Hits	52
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MYH14_HUMAN
NC score	0.042742 (rank : 43)	θ value	0.0193708 (rank : 24)
Query Neighborhood Hits	128	Target Neighborhood Hits	995	Shared Neighborhood Hits	61
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
NC score	0.042302 (rank : 44)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	128	Target Neighborhood Hits	1225	Shared Neighborhood Hits	85
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MAP9_HUMAN
NC score	0.041248 (rank : 45)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	128	Target Neighborhood Hits	518	Shared Neighborhood Hits	42
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

U2AFM_HUMAN
NC score	0.041139 (rank : 46)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	128	Target Neighborhood Hits	577	Shared Neighborhood Hits	48
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

MYH6_MOUSE
NC score	0.040892 (rank : 47)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	128	Target Neighborhood Hits	1501	Shared Neighborhood Hits	92
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_MOUSE
NC score	0.040100 (rank : 48)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	128	Target Neighborhood Hits	1600	Shared Neighborhood Hits	94
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

BPAEA_MOUSE
NC score	0.039868 (rank : 49)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	128	Target Neighborhood Hits	1480	Shared Neighborhood Hits	92
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYO6_HUMAN
NC score	0.039653 (rank : 50)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	128	Target Neighborhood Hits	727	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TAF7_MOUSE
NC score	0.038573 (rank : 51)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	128	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

MYH6_HUMAN
NC score	0.037609 (rank : 52)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	128	Target Neighborhood Hits	1426	Shared Neighborhood Hits	86
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH4_MOUSE
NC score	0.037014 (rank : 53)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	128	Target Neighborhood Hits	1476	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
NC score	0.036987 (rank : 54)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	128	Target Neighborhood Hits	1610	Shared Neighborhood Hits	94
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RPGR1_MOUSE
NC score	0.036928 (rank : 55)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	128	Target Neighborhood Hits	713	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

MYO6_MOUSE
NC score	0.036475 (rank : 56)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	128	Target Neighborhood Hits	586	Shared Neighborhood Hits	48
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

SYWM_MOUSE
NC score	0.035866 (rank : 57)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	128	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CYK1	Gene names	Wars2
Domain Architecture
Description	Tryptophanyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) ((Mt)TrpRS).

MAP1A_HUMAN
NC score	0.035189 (rank : 58)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	128	Target Neighborhood Hits	1626	Shared Neighborhood Hits	86
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TAF7_HUMAN
NC score	0.035026 (rank : 59)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	128	Target Neighborhood Hits	222	Shared Neighborhood Hits	28
SwissProt Accessions	Q15545, Q13036	Gene names	TAF7, TAF2F, TAFII55
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

REST_MOUSE
NC score	0.034380 (rank : 60)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	128	Target Neighborhood Hits	1506	Shared Neighborhood Hits	86
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

FLNA_HUMAN
NC score	0.034082 (rank : 61)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	128	Target Neighborhood Hits	138	Shared Neighborhood Hits	17
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

UBXD2_HUMAN
NC score	0.034002 (rank : 62)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	128	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

RENT2_HUMAN
NC score	0.033697 (rank : 63)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	128	Target Neighborhood Hits	618	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

TNNT2_HUMAN
NC score	0.033264 (rank : 64)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	128	Target Neighborhood Hits	433	Shared Neighborhood Hits	47
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

BRE1B_HUMAN
NC score	0.032732 (rank : 65)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	128	Target Neighborhood Hits	1040	Shared Neighborhood Hits	79
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRHY_HUMAN
NC score	0.032254 (rank : 66)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	128	Target Neighborhood Hits	1385	Shared Neighborhood Hits	63
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SMC4_HUMAN
NC score	0.032115 (rank : 67)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	128	Target Neighborhood Hits	937	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

BRE1B_MOUSE
NC score	0.031871 (rank : 68)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	128	Target Neighborhood Hits	970	Shared Neighborhood Hits	74
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CCD43_HUMAN
NC score	0.031482 (rank : 69)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	128	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MW1	Gene names	CCDC43
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

UBXD2_MOUSE
NC score	0.031077 (rank : 70)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	128	Target Neighborhood Hits	183	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

NIN_HUMAN
NC score	0.031033 (rank : 71)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	128	Target Neighborhood Hits	1416	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CCD46_HUMAN
NC score	0.030362 (rank : 72)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	128	Target Neighborhood Hits	1430	Shared Neighborhood Hits	90
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

U2AFL_HUMAN
NC score	0.030109 (rank : 73)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	128	Target Neighborhood Hits	503	Shared Neighborhood Hits	46
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

FLNA_MOUSE
NC score	0.029589 (rank : 74)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	128	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

CCD43_MOUSE
NC score	0.029475 (rank : 75)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	128	Target Neighborhood Hits	63	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CR29, Q6PDT2	Gene names	Ccdc43, D11Ertd707e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 43.

RFIP4_HUMAN
NC score	0.029113 (rank : 76)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	128	Target Neighborhood Hits	785	Shared Neighborhood Hits	74
SwissProt Accessions	Q86YS3, Q8N829, Q8NDT7, Q969D8	Gene names	RAB11FIP4, KIAA1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

CALD1_HUMAN
NC score	0.028662 (rank : 77)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	128	Target Neighborhood Hits	959	Shared Neighborhood Hits	66
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MYO7A_MOUSE
NC score	0.028445 (rank : 78)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	128	Target Neighborhood Hits	235	Shared Neighborhood Hits	25
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CP250_MOUSE
NC score	0.028426 (rank : 79)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	128	Target Neighborhood Hits	1583	Shared Neighborhood Hits	87
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CHCH3_MOUSE
NC score	0.027654 (rank : 80)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	128	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CROCC_HUMAN
NC score	0.027567 (rank : 81)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	128	Target Neighborhood Hits	1409	Shared Neighborhood Hits	79
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TPR_HUMAN
NC score	0.027483 (rank : 82)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	128	Target Neighborhood Hits	1921	Shared Neighborhood Hits	91
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

U2AFM_MOUSE
NC score	0.027333 (rank : 83)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	128	Target Neighborhood Hits	543	Shared Neighborhood Hits	47
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

TMF1_HUMAN
NC score	0.027032 (rank : 84)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	128	Target Neighborhood Hits	987	Shared Neighborhood Hits	74
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

PELP1_HUMAN
NC score	0.026697 (rank : 85)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	128	Target Neighborhood Hits	596	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

XE7_HUMAN
NC score	0.026631 (rank : 86)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	128	Target Neighborhood Hits	738	Shared Neighborhood Hits	54
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

NFM_HUMAN
NC score	0.026182 (rank : 87)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	128	Target Neighborhood Hits	1328	Shared Neighborhood Hits	70
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TNIP3_HUMAN
NC score	0.025927 (rank : 88)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	128	Target Neighborhood Hits	511	Shared Neighborhood Hits	59
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

GCP60_MOUSE
NC score	0.025330 (rank : 89)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	128	Target Neighborhood Hits	395	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BMP6, O35371	Gene names	Acbd3, Gcp60, Pap7
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

INCE_HUMAN
NC score	0.025031 (rank : 90)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	128	Target Neighborhood Hits	978	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MACF1_HUMAN
NC score	0.024870 (rank : 91)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	128	Target Neighborhood Hits	1341	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF1_MOUSE
NC score	0.024812 (rank : 92)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	128	Target Neighborhood Hits	1313	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

PININ_MOUSE
NC score	0.024126 (rank : 93)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	128	Target Neighborhood Hits	777	Shared Neighborhood Hits	68
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

GCP60_HUMAN
NC score	0.024115 (rank : 94)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	128	Target Neighborhood Hits	419	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3P7, Q5VTJ0, Q6P9F1, Q8IZC5, Q8N4D6, Q9H6U3	Gene names	ACBD3, GCP60
Domain Architecture	No domain graphic available
Description	Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi phosphoprotein 1) (GOLPH1) (Golgi complex-associated protein 1) (GOCAP1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7).

SMC4_MOUSE
NC score	0.023830 (rank : 95)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	128	Target Neighborhood Hits	830	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

MAP1B_MOUSE
NC score	0.023422 (rank : 96)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	128	Target Neighborhood Hits	977	Shared Neighborhood Hits	37
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

ITSN2_MOUSE
NC score	0.023304 (rank : 97)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	128	Target Neighborhood Hits	1371	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RFIP4_MOUSE
NC score	0.022923 (rank : 98)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	128	Target Neighborhood Hits	708	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

INCE_MOUSE
NC score	0.022877 (rank : 99)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	128	Target Neighborhood Hits	903	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

NEMO_MOUSE
NC score	0.022635 (rank : 100)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	128	Target Neighborhood Hits	658	Shared Neighborhood Hits	62
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TSC1_HUMAN
NC score	0.022545 (rank : 101)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	128	Target Neighborhood Hits	765	Shared Neighborhood Hits	61
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

NUMA1_HUMAN
NC score	0.021876 (rank : 102)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	128	Target Neighborhood Hits	1523	Shared Neighborhood Hits	84
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

AZI1_MOUSE
NC score	0.021443 (rank : 103)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	128	Target Neighborhood Hits	990	Shared Neighborhood Hits	82
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

HOOK2_MOUSE
NC score	0.020647 (rank : 104)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	128	Target Neighborhood Hits	736	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

SRCH_HUMAN
NC score	0.020100 (rank : 105)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	128	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

PWP1_MOUSE
NC score	0.018898 (rank : 106)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	128	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LL5, Q9D6T6	Gene names	Pwp1
Domain Architecture	No domain graphic available
Description	Periodic tryptophan protein 1 homolog.

NFM_MOUSE
NC score	0.018265 (rank : 107)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	128	Target Neighborhood Hits	1159	Shared Neighborhood Hits	70
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PLEC1_HUMAN
NC score	0.017607 (rank : 108)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	128	Target Neighborhood Hits	1326	Shared Neighborhood Hits	66
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

BAZ2A_HUMAN
NC score	0.016962 (rank : 109)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	128	Target Neighborhood Hits	780	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

ANR12_HUMAN
NC score	0.015518 (rank : 110)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	128	Target Neighborhood Hits	1081	Shared Neighborhood Hits	66
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

KIF4A_MOUSE
NC score	0.015453 (rank : 111)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	128	Target Neighborhood Hits	1033	Shared Neighborhood Hits	80
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

ANR38_MOUSE
NC score	0.015332 (rank : 112)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	128	Target Neighborhood Hits	512	Shared Neighborhood Hits	32
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

PWP1_HUMAN
NC score	0.014916 (rank : 113)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	128	Target Neighborhood Hits	261	Shared Neighborhood Hits	3
SwissProt Accessions	Q13610	Gene names	PWP1
Domain Architecture
Description	Periodic tryptophan protein 1 homolog (Keratinocyte protein IEF SSP 9502).

FLNB_HUMAN
NC score	0.013560 (rank : 114)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	128	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

K2C4_MOUSE
NC score	0.013207 (rank : 115)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	128	Target Neighborhood Hits	521	Shared Neighborhood Hits	47
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

FLNB_MOUSE
NC score	0.012548 (rank : 116)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	128	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

SAFB2_MOUSE
NC score	0.012353 (rank : 117)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	128	Target Neighborhood Hits	581	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

ITSN2_HUMAN
NC score	0.011519 (rank : 118)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	128	Target Neighborhood Hits	1173	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

VPS35_MOUSE
NC score	0.011327 (rank : 119)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	128	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQH3, Q61123	Gene names	Vps35, Mem3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (Maternal-embryonic 3).

VPS35_HUMAN
NC score	0.011327 (rank : 120)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	128	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QK1, Q561W2, Q9H016, Q9H096, Q9H4P3, Q9H8J0, Q9NRS7, Q9NVG2, Q9NX80, Q9NZK2	Gene names	VPS35, MEM3
Domain Architecture
Description	Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) (hVPS35) (Maternal-embryonic 3).

BSN_HUMAN
NC score	0.010652 (rank : 121)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	128	Target Neighborhood Hits	1537	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
NC score	0.008314 (rank : 122)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	128	Target Neighborhood Hits	2057	Shared Neighborhood Hits	47
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SLK_MOUSE
NC score	0.007704 (rank : 123)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	128	Target Neighborhood Hits	1798	Shared Neighborhood Hits	86
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SLK_HUMAN
NC score	0.006307 (rank : 124)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	128	Target Neighborhood Hits	1775	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

M4K4_HUMAN
NC score	0.004328 (rank : 125)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	128	Target Neighborhood Hits	1589	Shared Neighborhood Hits	54
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
NC score	0.003232 (rank : 126)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	128	Target Neighborhood Hits	1560	Shared Neighborhood Hits	52
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_MOUSE
NC score	0.001602 (rank : 127)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	128	Target Neighborhood Hits	1451	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.001210 (rank : 128)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	128	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

TESK2_MOUSE
NC score	-0.002251 (rank : 129)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	128	Target Neighborhood Hits	833	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).