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Network neighborhood for query Sequence : HS70A_MOUSE

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HS70A_MOUSE
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRP78_HUMAN
θ value	0 (rank : 1)	NC score	0.983526 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	218	Shared Neighborhood Hits	44
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	0 (rank : 2)	NC score	0.983423 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	216	Shared Neighborhood Hits	44
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

HS70A_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	0 (rank : 4)	NC score	0.999929 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70L_HUMAN
θ value	0 (rank : 5)	NC score	0.997308 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70L_MOUSE
θ value	0 (rank : 6)	NC score	0.997560 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP71_HUMAN
θ value	0 (rank : 7)	NC score	0.998478 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HSP72_HUMAN
θ value	0 (rank : 8)	NC score	0.996755 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
θ value	0 (rank : 9)	NC score	0.996492 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP76_HUMAN
θ value	0 (rank : 10)	NC score	0.994840 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
θ value	0 (rank : 11)	NC score	0.993284 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	150	Shared Neighborhood Hits	49
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	0 (rank : 12)	NC score	0.992631 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP75_HUMAN
θ value	1.92261e-143 (rank : 13)	NC score	0.981830 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

GRP75_MOUSE
θ value	2.77624e-142 (rank : 14)	NC score	0.982683 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HS74L_MOUSE
θ value	2.92676e-75 (rank : 15)	NC score	0.902718 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_MOUSE
θ value	8.51556e-75 (rank : 16)	NC score	0.891039 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	257	Shared Neighborhood Hits	38
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HSP74_HUMAN
θ value	1.45253e-74 (rank : 17)	NC score	0.902589 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS74L_HUMAN
θ value	1.22964e-73 (rank : 18)	NC score	0.901294 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

STCH_HUMAN
θ value	2.09745e-73 (rank : 19)	NC score	0.963436 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
θ value	1.35953e-72 (rank : 20)	NC score	0.963106 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS105_HUMAN
θ value	1.50314e-71 (rank : 21)	NC score	0.898128 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	1.96316e-71 (rank : 22)	NC score	0.905591 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

OXRP_HUMAN
θ value	9.16162e-53 (rank : 23)	NC score	0.874404 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	544	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ANR45_HUMAN
θ value	5.44631e-05 (rank : 24)	NC score	0.253784 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
θ value	0.00298849 (rank : 25)	NC score	0.144998 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

ANR45_MOUSE
θ value	0.0148317 (rank : 26)	NC score	0.194523 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

MYH11_HUMAN
θ value	0.0330416 (rank : 27)	NC score	0.045489 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	1806	Shared Neighborhood Hits	52
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

E2AK2_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.007525 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	864	Shared Neighborhood Hits	6
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

HS12B_HUMAN
θ value	0.0563607 (rank : 29)	NC score	0.091004 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

MYH10_HUMAN
θ value	0.0563607 (rank : 30)	NC score	0.041811 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	1620	Shared Neighborhood Hits	47
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.041464 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	1612	Shared Neighborhood Hits	47
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

LAMB1_MOUSE
θ value	0.125558 (rank : 32)	NC score	0.027497 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	919	Shared Neighborhood Hits	29
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH9_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.040976 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	1762	Shared Neighborhood Hits	53
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.039526 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	1829	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PCIF1_HUMAN
θ value	0.125558 (rank : 35)	NC score	0.065441 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

PCIF1_MOUSE
θ value	0.163984 (rank : 36)	NC score	0.057112 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

MYH11_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.038378 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	1777	Shared Neighborhood Hits	47
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

BPAEA_MOUSE
θ value	0.62314 (rank : 38)	NC score	0.027808 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	1480	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

COVA1_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.062058 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	416	Shared Neighborhood Hits	26
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

FA44A_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.057469 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

K2C3_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.018726 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

COVA1_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.050280 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

FLNA_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.027887 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

GOGA5_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.018501 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	1168	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

U2AFM_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.029952 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

DYXC1_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.046237 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

DZIP3_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.018805 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	414	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

GOGB1_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.033348 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	2297	Shared Neighborhood Hits	50
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH7_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.029941 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	1559	Shared Neighborhood Hits	44
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

ZN644_HUMAN
θ value	2.36792 (rank : 50)	NC score	-0.000271 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	704	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).

DYH5_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.025864 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

MAP9_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.041422 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	529	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYH14_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.030999 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	1225	Shared Neighborhood Hits	40
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MY18B_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.021830 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	1299	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH3_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.022096 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	1660	Shared Neighborhood Hits	41
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH6_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.026289 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	1426	Shared Neighborhood Hits	40
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PDP1_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.021063 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.020982 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

BAZ2A_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.016456 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	780	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BPA1_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.023029 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	1477	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DYH5_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.025331 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

FLNA_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.023321 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

K2C7_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.011913 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	369	Shared Neighborhood Hits	27
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

MYH14_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.033272 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	995	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH6_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.029017 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	1501	Shared Neighborhood Hits	43
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

UBXD2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.034721 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

UBXD2_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.032175 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

CAF1A_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.056046 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

EEA1_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.017770 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	1796	Shared Neighborhood Hits	42
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

K2C1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.011930 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

APOL2_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.010027 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQE5, O95915, Q5TH96, Q969T6, Q9BT28, Q9UGT1, Q9UH10	Gene names	APOL2
Domain Architecture
Description	Apolipoprotein-L2 (Apolipoprotein L-II) (ApoL-II).

CNOT3_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.009662 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	504	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

TNNT2_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.029125 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	433	Shared Neighborhood Hits	25
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

SFR12_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.060287 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

Hits sorted by NC score

HS70A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	73	Target Neighborhood Hits	73	Shared Neighborhood Hits	73
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
NC score	0.999929 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	73	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HSP71_HUMAN
NC score	0.998478 (rank : 3)	θ value	0 (rank : 7)
Query Neighborhood Hits	73	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70L_MOUSE
NC score	0.997560 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	73	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HS70L_HUMAN
NC score	0.997308 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	73	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HSP72_HUMAN
NC score	0.996755 (rank : 6)	θ value	0 (rank : 8)
Query Neighborhood Hits	73	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
NC score	0.996492 (rank : 7)	θ value	0 (rank : 9)
Query Neighborhood Hits	73	Target Neighborhood Hits	83	Shared Neighborhood Hits	45
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP76_HUMAN
NC score	0.994840 (rank : 8)	θ value	0 (rank : 10)
Query Neighborhood Hits	73	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
NC score	0.993284 (rank : 9)	θ value	0 (rank : 11)
Query Neighborhood Hits	73	Target Neighborhood Hits	150	Shared Neighborhood Hits	49
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
NC score	0.992631 (rank : 10)	θ value	0 (rank : 12)
Query Neighborhood Hits	73	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP78_HUMAN
NC score	0.983526 (rank : 11)	θ value	0 (rank : 1)
Query Neighborhood Hits	73	Target Neighborhood Hits	218	Shared Neighborhood Hits	44
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.983423 (rank : 12)	θ value	0 (rank : 2)
Query Neighborhood Hits	73	Target Neighborhood Hits	216	Shared Neighborhood Hits	44
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP75_MOUSE
NC score	0.982683 (rank : 13)	θ value	2.77624e-142 (rank : 14)
Query Neighborhood Hits	73	Target Neighborhood Hits	88	Shared Neighborhood Hits	32
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
NC score	0.981830 (rank : 14)	θ value	1.92261e-143 (rank : 13)
Query Neighborhood Hits	73	Target Neighborhood Hits	97	Shared Neighborhood Hits	34
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

STCH_HUMAN
NC score	0.963436 (rank : 15)	θ value	2.09745e-73 (rank : 19)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
NC score	0.963106 (rank : 16)	θ value	1.35953e-72 (rank : 20)
Query Neighborhood Hits	73	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HS105_MOUSE
NC score	0.905591 (rank : 17)	θ value	1.96316e-71 (rank : 22)
Query Neighborhood Hits	73	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_MOUSE
NC score	0.902718 (rank : 18)	θ value	2.92676e-75 (rank : 15)
Query Neighborhood Hits	73	Target Neighborhood Hits	141	Shared Neighborhood Hits	30
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
NC score	0.902589 (rank : 19)	θ value	1.45253e-74 (rank : 17)
Query Neighborhood Hits	73	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS74L_HUMAN
NC score	0.901294 (rank : 20)	θ value	1.22964e-73 (rank : 18)
Query Neighborhood Hits	73	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_HUMAN
NC score	0.898128 (rank : 21)	θ value	1.50314e-71 (rank : 21)
Query Neighborhood Hits	73	Target Neighborhood Hits	209	Shared Neighborhood Hits	29
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HSP74_MOUSE
NC score	0.891039 (rank : 22)	θ value	8.51556e-75 (rank : 16)
Query Neighborhood Hits	73	Target Neighborhood Hits	257	Shared Neighborhood Hits	38
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

OXRP_HUMAN
NC score	0.874404 (rank : 23)	θ value	9.16162e-53 (rank : 23)
Query Neighborhood Hits	73	Target Neighborhood Hits	544	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ANR45_HUMAN
NC score	0.253784 (rank : 24)	θ value	5.44631e-05 (rank : 24)
Query Neighborhood Hits	73	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
NC score	0.194523 (rank : 25)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	73	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
NC score	0.144998 (rank : 26)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS12B_HUMAN
NC score	0.091004 (rank : 27)	θ value	0.0563607 (rank : 29)
Query Neighborhood Hits	73	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

PCIF1_HUMAN
NC score	0.065441 (rank : 28)	θ value	0.125558 (rank : 35)
Query Neighborhood Hits	73	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

COVA1_HUMAN
NC score	0.062058 (rank : 29)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	73	Target Neighborhood Hits	416	Shared Neighborhood Hits	26
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

SFR12_HUMAN
NC score	0.060287 (rank : 30)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	73	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

FA44A_HUMAN
NC score	0.057469 (rank : 31)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	73	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

PCIF1_MOUSE
NC score	0.057112 (rank : 32)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	73	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

CAF1A_HUMAN
NC score	0.056046 (rank : 33)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	73	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

COVA1_MOUSE
NC score	0.050280 (rank : 34)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	73	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0Z2, Q8BY59, Q8R372	Gene names	Cova1
Domain Architecture	No domain graphic available
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

DYXC1_HUMAN
NC score	0.046237 (rank : 35)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	73	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

MYH11_HUMAN
NC score	0.045489 (rank : 36)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	73	Target Neighborhood Hits	1806	Shared Neighborhood Hits	52
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH10_HUMAN
NC score	0.041811 (rank : 37)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	73	Target Neighborhood Hits	1620	Shared Neighborhood Hits	47
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.041464 (rank : 38)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	73	Target Neighborhood Hits	1612	Shared Neighborhood Hits	47
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MAP9_MOUSE
NC score	0.041422 (rank : 39)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	73	Target Neighborhood Hits	529	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MYH9_HUMAN
NC score	0.040976 (rank : 40)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	73	Target Neighborhood Hits	1762	Shared Neighborhood Hits	53
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.039526 (rank : 41)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	73	Target Neighborhood Hits	1829	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH11_MOUSE
NC score	0.038378 (rank : 42)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	73	Target Neighborhood Hits	1777	Shared Neighborhood Hits	47
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

UBXD2_HUMAN
NC score	0.034721 (rank : 43)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	73	Target Neighborhood Hits	241	Shared Neighborhood Hits	18
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

GOGB1_HUMAN
NC score	0.033348 (rank : 44)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	73	Target Neighborhood Hits	2297	Shared Neighborhood Hits	50
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH14_HUMAN
NC score	0.033272 (rank : 45)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	73	Target Neighborhood Hits	995	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

UBXD2_MOUSE
NC score	0.032175 (rank : 46)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	73	Target Neighborhood Hits	183	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

MYH14_MOUSE
NC score	0.030999 (rank : 47)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	73	Target Neighborhood Hits	1225	Shared Neighborhood Hits	40
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

U2AFM_HUMAN
NC score	0.029952 (rank : 48)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	73	Target Neighborhood Hits	577	Shared Neighborhood Hits	24
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

MYH7_HUMAN
NC score	0.029941 (rank : 49)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	73	Target Neighborhood Hits	1559	Shared Neighborhood Hits	44
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TNNT2_HUMAN
NC score	0.029125 (rank : 50)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	73	Target Neighborhood Hits	433	Shared Neighborhood Hits	25
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MYH6_MOUSE
NC score	0.029017 (rank : 51)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	73	Target Neighborhood Hits	1501	Shared Neighborhood Hits	43
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

FLNA_HUMAN
NC score	0.027887 (rank : 52)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	73	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

BPAEA_MOUSE
NC score	0.027808 (rank : 53)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	73	Target Neighborhood Hits	1480	Shared Neighborhood Hits	43
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

LAMB1_MOUSE
NC score	0.027497 (rank : 54)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	73	Target Neighborhood Hits	919	Shared Neighborhood Hits	29
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH6_HUMAN
NC score	0.026289 (rank : 55)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	73	Target Neighborhood Hits	1426	Shared Neighborhood Hits	40
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

DYH5_HUMAN
NC score	0.025864 (rank : 56)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	73	Target Neighborhood Hits	323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

DYH5_MOUSE
NC score	0.025331 (rank : 57)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	73	Target Neighborhood Hits	286	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

FLNA_MOUSE
NC score	0.023321 (rank : 58)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	73	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

BPA1_MOUSE
NC score	0.023029 (rank : 59)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	73	Target Neighborhood Hits	1477	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYH3_HUMAN
NC score	0.022096 (rank : 60)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	73	Target Neighborhood Hits	1660	Shared Neighborhood Hits	41
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MY18B_HUMAN
NC score	0.021830 (rank : 61)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	73	Target Neighborhood Hits	1299	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

PDP1_HUMAN
NC score	0.021063 (rank : 62)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	73	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P0J1, Q5U5K1	Gene names	PDP1, PDP, PPM2C
Domain Architecture
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

PDP1_MOUSE
NC score	0.020982 (rank : 63)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	73	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q3UV70	Gene names	Pdp1, Ppm2c
Domain Architecture	No domain graphic available
Description	[Pyruvate dehydrogenase [lipoamide]]-phosphatase 1, mitochondrial precursor (EC 3.1.3.43) (PDP 1) (Pyruvate dehydrogenase phosphatase, catalytic subunit 1) (PDPC 1) (Protein phosphatase 2C).

DZIP3_MOUSE
NC score	0.018805 (rank : 64)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	73	Target Neighborhood Hits	414	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

K2C3_HUMAN
NC score	0.018726 (rank : 65)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	73	Target Neighborhood Hits	443	Shared Neighborhood Hits	29
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

GOGA5_HUMAN
NC score	0.018501 (rank : 66)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	73	Target Neighborhood Hits	1168	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

EEA1_HUMAN
NC score	0.017770 (rank : 67)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	73	Target Neighborhood Hits	1796	Shared Neighborhood Hits	42
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

BAZ2A_HUMAN
NC score	0.016456 (rank : 68)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	73	Target Neighborhood Hits	780	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

K2C1_HUMAN
NC score	0.011930 (rank : 69)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	73	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

K2C7_HUMAN
NC score	0.011913 (rank : 70)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	73	Target Neighborhood Hits	369	Shared Neighborhood Hits	27
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

APOL2_HUMAN
NC score	0.010027 (rank : 71)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	73	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQE5, O95915, Q5TH96, Q969T6, Q9BT28, Q9UGT1, Q9UH10	Gene names	APOL2
Domain Architecture
Description	Apolipoprotein-L2 (Apolipoprotein L-II) (ApoL-II).

CNOT3_MOUSE
NC score	0.009662 (rank : 72)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	73	Target Neighborhood Hits	504	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

E2AK2_MOUSE
NC score	0.007525 (rank : 73)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	73	Target Neighborhood Hits	864	Shared Neighborhood Hits	6
SwissProt Accessions	Q03963, Q61742, Q62026	Gene names	Eif2ak2, Pkr, Prkr, Tik
Domain Architecture
Description	Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (p68 kinase) (P1/eIF-2A protein kinase) (Serine/threonine-protein kinase TIK).

ZN644_HUMAN
NC score	-0.000271 (rank : 74)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	73	Target Neighborhood Hits	704	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H582, Q5TCC0, Q6BEP7, Q6P446, Q6PI06, Q7LG67, Q9ULJ9	Gene names	ZNF644, KIAA1221, ZEP2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 644 (Zinc finger motif enhancer-binding protein 2) (Zep-2).