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Network neighborhood for query Sequence : HS12B_MOUSE

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HS12B_MOUSE
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS12A_HUMAN
θ value	0 (rank : 1)	NC score	0.982400 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O43301	Gene names	HSPA12A, KIAA0417
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

HS12A_MOUSE
θ value	0 (rank : 2)	NC score	0.981874 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0U4, Q3UQZ8	Gene names	Hspa12a
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

HS12B_HUMAN
θ value	0 (rank : 3)	NC score	0.996701 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

HS12B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS70L_HUMAN
θ value	0.00175202 (rank : 5)	NC score	0.145050 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70A_MOUSE
θ value	0.00298849 (rank : 6)	NC score	0.144998 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	0.00298849 (rank : 7)	NC score	0.144997 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70L_MOUSE
θ value	0.00298849 (rank : 8)	NC score	0.143839 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP71_HUMAN
θ value	0.00390308 (rank : 9)	NC score	0.145540 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

GRP75_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.159136 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

GRP75_MOUSE
θ value	0.0736092 (rank : 11)	NC score	0.156083 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HSP76_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.137134 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	128	Shared Neighborhood Hits	20
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

VGFR1_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.008686 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	1109	Shared Neighborhood Hits	3
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

HSP7C_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.126698 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	150	Shared Neighborhood Hits	19
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.126611 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	166	Shared Neighborhood Hits	19
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

GRP78_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.124514 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.124494 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

HSP72_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.125555 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

CUTL1_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.011013 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	1574	Shared Neighborhood Hits	8
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

HSP72_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.125057 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

PAPS2_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.041392 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O95340, Q9BZL2, Q9P0G6, Q9UHM1, Q9UKD3, Q9UP30	Gene names	PAPSS2, ATPSK2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS2_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.037503 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

BRE1B_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.012236 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	1040	Shared Neighborhood Hits	11
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.012942 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	970	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CUTL1_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.010643 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	1620	Shared Neighborhood Hits	8
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

HSP74_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.094785 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

TTC7A_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.014690 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

HSP74_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.095804 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	154	Shared Neighborhood Hits	17
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

NCOR1_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.008585 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	521	Shared Neighborhood Hits	8
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

B3A3_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.004559 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

MED12_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.012199 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

NOMO2_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.011960 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JPE7	Gene names	NOMO2
Domain Architecture	No domain graphic available
Description	Nodal modulator 2 precursor (pM5 protein 2).

PCLO_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.001713 (rank : 41)
Query Neighborhood Hits	34	Target Neighborhood Hits	2275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TGM1_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.009265 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLF6, Q8R0T9	Gene names	Tgm1
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

HS105_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.091420 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.092282 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.091869 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.092294 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	17
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

OXRP_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.091838 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	544	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

STCH_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.108234 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.121666 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

Hits sorted by NC score

HS12B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

HS12B_HUMAN
NC score	0.996701 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MM6, Q9BR52	Gene names	HSPA12B, C20orf60
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 12B.

HS12A_HUMAN
NC score	0.982400 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O43301	Gene names	HSPA12A, KIAA0417
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

HS12A_MOUSE
NC score	0.981874 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K0U4, Q3UQZ8	Gene names	Hspa12a
Domain Architecture
Description	Heat shock 70 kDa protein 12A.

GRP75_HUMAN
NC score	0.159136 (rank : 5)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

GRP75_MOUSE
NC score	0.156083 (rank : 6)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HSP71_HUMAN
NC score	0.145540 (rank : 7)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	87	Shared Neighborhood Hits	20
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70L_HUMAN
NC score	0.145050 (rank : 8)	θ value	0.00175202 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70A_MOUSE
NC score	0.144998 (rank : 9)	θ value	0.00298849 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
NC score	0.144997 (rank : 10)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70L_MOUSE
NC score	0.143839 (rank : 11)	θ value	0.00298849 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP76_HUMAN
NC score	0.137134 (rank : 12)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	128	Shared Neighborhood Hits	20
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
NC score	0.126698 (rank : 13)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	150	Shared Neighborhood Hits	19
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
NC score	0.126611 (rank : 14)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	166	Shared Neighborhood Hits	19
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP72_MOUSE
NC score	0.125555 (rank : 15)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	83	Shared Neighborhood Hits	18
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

HSP72_HUMAN
NC score	0.125057 (rank : 16)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

GRP78_HUMAN
NC score	0.124514 (rank : 17)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.124494 (rank : 18)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

STCH_MOUSE
NC score	0.121666 (rank : 19)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	34	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_HUMAN
NC score	0.108234 (rank : 20)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

HSP74_HUMAN
NC score	0.095804 (rank : 21)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	154	Shared Neighborhood Hits	17
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HSP74_MOUSE
NC score	0.094785 (rank : 22)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HS74L_MOUSE
NC score	0.092294 (rank : 23)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	17
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_MOUSE
NC score	0.092282 (rank : 24)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	34	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_HUMAN
NC score	0.091869 (rank : 25)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	34	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

OXRP_HUMAN
NC score	0.091838 (rank : 26)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	34	Target Neighborhood Hits	544	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

HS105_HUMAN
NC score	0.091420 (rank : 27)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	34	Target Neighborhood Hits	209	Shared Neighborhood Hits	17
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

PAPS2_HUMAN
NC score	0.041392 (rank : 28)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	O95340, Q9BZL2, Q9P0G6, Q9UHM1, Q9UKD3, Q9UP30	Gene names	PAPSS2, ATPSK2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

PAPS2_MOUSE
NC score	0.037503 (rank : 29)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

TTC7A_HUMAN
NC score	0.014690 (rank : 30)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

BRE1B_MOUSE
NC score	0.012942 (rank : 31)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	970	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.012236 (rank : 32)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	1040	Shared Neighborhood Hits	11
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MED12_HUMAN
NC score	0.012199 (rank : 33)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

NOMO2_HUMAN
NC score	0.011960 (rank : 34)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JPE7	Gene names	NOMO2
Domain Architecture	No domain graphic available
Description	Nodal modulator 2 precursor (pM5 protein 2).

CUTL1_HUMAN
NC score	0.011013 (rank : 35)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	1574	Shared Neighborhood Hits	8
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
NC score	0.010643 (rank : 36)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	1620	Shared Neighborhood Hits	8
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TGM1_MOUSE
NC score	0.009265 (rank : 37)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLF6, Q8R0T9	Gene names	Tgm1
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Transglutaminase K) (TGase K) (TGK) (TG(K)) (Transglutaminase-1) (Epidermal TGase).

VGFR1_HUMAN
NC score	0.008686 (rank : 38)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	1109	Shared Neighborhood Hits	3
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

NCOR1_MOUSE
NC score	0.008585 (rank : 39)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	521	Shared Neighborhood Hits	8
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

B3A3_MOUSE
NC score	0.004559 (rank : 40)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

PCLO_MOUSE
NC score	0.001713 (rank : 41)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	2275	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).