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Network neighborhood for query Sequence : HS74L_HUMAN

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HS74L_HUMAN
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS105_HUMAN
θ value	0 (rank : 1)	NC score	0.976404 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	209	Shared Neighborhood Hits	51
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HS105_MOUSE
θ value	0 (rank : 2)	NC score	0.982204 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HS74L_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_MOUSE
θ value	0 (rank : 4)	NC score	0.989296 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HSP74_HUMAN
θ value	0 (rank : 5)	NC score	0.979285 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HSP74_MOUSE
θ value	0 (rank : 6)	NC score	0.971669 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	257	Shared Neighborhood Hits	77
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

OXRP_HUMAN
θ value	1.44917e-82 (rank : 7)	NC score	0.900607 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	544	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

HS70L_HUMAN
θ value	1.71583e-75 (rank : 8)	NC score	0.900461 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HS70L_MOUSE
θ value	1.89707e-74 (rank : 9)	NC score	0.901134 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

HSP71_HUMAN
θ value	1.89707e-74 (rank : 10)	NC score	0.901159 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70A_MOUSE
θ value	1.22964e-73 (rank : 11)	NC score	0.901294 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HS70B_MOUSE
θ value	1.22964e-73 (rank : 12)	NC score	0.901311 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HSP76_HUMAN
θ value	1.35953e-72 (rank : 13)	NC score	0.903248 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

HSP7C_HUMAN
θ value	1.7756e-72 (rank : 14)	NC score	0.899171 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	48
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	1.7756e-72 (rank : 15)	NC score	0.899703 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP72_HUMAN
θ value	2.3998e-69 (rank : 16)	NC score	0.898492 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
θ value	5.34618e-69 (rank : 17)	NC score	0.897645 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

GRP78_MOUSE
θ value	1.31681e-67 (rank : 18)	NC score	0.896654 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	216	Shared Neighborhood Hits	56
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

GRP78_HUMAN
θ value	1.71981e-67 (rank : 19)	NC score	0.896740 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP75_MOUSE
θ value	4.53632e-60 (rank : 20)	NC score	0.902166 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

GRP75_HUMAN
θ value	7.73779e-60 (rank : 21)	NC score	0.901015 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

STCH_HUMAN
θ value	1.57e-36 (rank : 22)	NC score	0.890983 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
θ value	4.27553e-34 (rank : 23)	NC score	0.886232 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

MRCKA_HUMAN
θ value	1.43324e-05 (rank : 24)	NC score	0.036916 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	1999	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

CJ118_MOUSE
θ value	0.000158464 (rank : 25)	NC score	0.064754 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	1132	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

MYH8_MOUSE
θ value	0.00035302 (rank : 26)	NC score	0.077666 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	1600	Shared Neighborhood Hits	94
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH10_HUMAN
θ value	0.00228821 (rank : 27)	NC score	0.083130 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	1620	Shared Neighborhood Hits	98
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH4_MOUSE
θ value	0.00665767 (rank : 28)	NC score	0.074090 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	1476	Shared Neighborhood Hits	91
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

CCD91_HUMAN
θ value	0.0113563 (rank : 29)	NC score	0.086039 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	868	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

MYH2_HUMAN
θ value	0.0148317 (rank : 30)	NC score	0.075603 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	1491	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TACC3_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.064823 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	779	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

LIPA2_MOUSE
θ value	0.0193708 (rank : 32)	NC score	0.062151 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	1282	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH10_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.082122 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	1612	Shared Neighborhood Hits	98
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TITIN_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.018108 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	2923	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MYH4_HUMAN
θ value	0.0330416 (rank : 35)	NC score	0.074275 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	1377	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

RYR1_HUMAN
θ value	0.0330416 (rank : 36)	NC score	0.038639 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

GOGA4_MOUSE
θ value	0.0431538 (rank : 37)	NC score	0.063790 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH9_HUMAN
θ value	0.0431538 (rank : 38)	NC score	0.082781 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	1762	Shared Neighborhood Hits	101
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CCD91_MOUSE
θ value	0.0563607 (rank : 39)	NC score	0.068550 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	699	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

RP1L1_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.025196 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

MYH8_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.073585 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	1610	Shared Neighborhood Hits	92
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

HOOK1_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.064960 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	942	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MYH1_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.072900 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	1461	Shared Neighborhood Hits	89
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH1_HUMAN
θ value	0.163984 (rank : 44)	NC score	0.074273 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	1478	Shared Neighborhood Hits	90
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

EEA1_HUMAN
θ value	0.21417 (rank : 45)	NC score	0.059980 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	1796	Shared Neighborhood Hits	93
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KTN1_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.052710 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	1197	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

ROCK2_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.026929 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	2073	Shared Neighborhood Hits	88
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	0.21417 (rank : 48)	NC score	0.028113 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	2072	Shared Neighborhood Hits	85
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

STK4_HUMAN
θ value	0.21417 (rank : 49)	NC score	0.004559 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	870	Shared Neighborhood Hits	13
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

STK4_MOUSE
θ value	0.21417 (rank : 50)	NC score	0.004298 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	873	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

LIPA2_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.057989 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	1044	Shared Neighborhood Hits	81
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYH6_MOUSE
θ value	0.279714 (rank : 52)	NC score	0.075367 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	1501	Shared Neighborhood Hits	94
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

ASPH_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.051565 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

ENKUR_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.078883 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

HOOK1_MOUSE
θ value	0.365318 (rank : 55)	NC score	0.057284 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

K0256_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.037933 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

NFM_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.044931 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	1328	Shared Neighborhood Hits	91
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

TACC3_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.070079 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	607	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

MYH7_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.075187 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	1559	Shared Neighborhood Hits	94
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH9_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.078994 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	1829	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO5B_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.069478 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	911	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

TRHY_HUMAN
θ value	0.62314 (rank : 62)	NC score	0.063694 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	1385	Shared Neighborhood Hits	91
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

AL2S8_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.022149 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N187, Q8ND29, Q8WXC0, Q96J78, Q96Q38, Q96Q39, Q9H712	Gene names	ALS2CR8, CARF
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24).

CILP1_MOUSE
θ value	0.813845 (rank : 64)	NC score	0.020916 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

IF2P_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.074860 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	889	Shared Neighborhood Hits	85
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

KIF23_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.051180 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	618	Shared Neighborhood Hits	72
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

PMS1_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.017882 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

SMC4_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.055443 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	937	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

TRIPB_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.056798 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	1587	Shared Neighborhood Hits	99
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CILP1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.021931 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

MYH13_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.073149 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	1504	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH6_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.071665 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	1426	Shared Neighborhood Hits	91
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SMC4_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.049725 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	830	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CN130_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.029546 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

ERC2_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.056734 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	1166	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

NP1L2_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.011000 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51860	Gene names	Nap1l2, Bpx
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

PPRB_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.015814 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	311	Shared Neighborhood Hits	8
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

RBP22_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.018842 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

SETB1_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.015684 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SYNE1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.048120 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	1484	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ERC2_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.056265 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	1156	Shared Neighborhood Hits	86
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

GOGA4_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.067737 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	2034	Shared Neighborhood Hits	99
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HOME2_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.049587 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	882	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

MOES_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.031401 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	892	Shared Neighborhood Hits	69
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYH11_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.078373 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	1777	Shared Neighborhood Hits	99
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYST4_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.009964 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

SYCP1_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.072710 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	1456	Shared Neighborhood Hits	95
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TSKS_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.030151 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

HAP1_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.039235 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	388	Shared Neighborhood Hits	51
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

LUZP1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.054052 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	739	Shared Neighborhood Hits	71
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

MYH3_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.069934 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	1660	Shared Neighborhood Hits	97
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PCNT_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.045657 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	1207	Shared Neighborhood Hits	80
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

RGPD8_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.018014 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	27
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

TRM6_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.013629 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJA5, Q76P92, Q9BQV5, Q9ULR7	Gene names	TRM6, KIAA1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

ANR12_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.035288 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	1081	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

C8AP2_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.035934 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

FINC_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.010232 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	3.0926 (rank : 98)	NC score	0.010284 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

GCC2_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.058926 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	1558	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

HOOK2_HUMAN
θ value	3.0926 (rank : 100)	NC score	0.049108 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	714	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

LEO1_HUMAN
θ value	3.0926 (rank : 101)	NC score	0.033567 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	958	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MYH11_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.083338 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	1806	Shared Neighborhood Hits	101
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PDC10_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.030584 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BUL8, O14811	Gene names	PDCD10, CCM3, TFAR15
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 10 (TF-1 cell apoptosis-related protein 15) (Cerebral cavernous malformations 3 protein).

PDC10_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.030633 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE70, Q9DAR3, Q9WV43	Gene names	Pdcd10, Tfar15
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 10 (TF-1 cell apoptosis-related protein 15).

PKHA5_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.031628 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RBP24_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.058944 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	1559	Shared Neighborhood Hits	87
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SMAL1_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.008964 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SPTN5_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.024385 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TMF1_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.053796 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	987	Shared Neighborhood Hits	81
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TRI44_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.020457 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

KI21B_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.030879 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

MY18A_HUMAN
θ value	4.03905 (rank : 112)	NC score	0.059656 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	1929	Shared Neighborhood Hits	90
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.058767 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SETB1_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.014822 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TGM5_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.008930 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

TPM1_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.047687 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	716	Shared Neighborhood Hits	76
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.047605 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	729	Shared Neighborhood Hits	77
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TTC1_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.035455 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ZN638_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.015116 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

2ACA_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.021704 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

C8AP2_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.019993 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	548	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CENPE_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.055703 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CK5P2_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.045402 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	1433	Shared Neighborhood Hits	85
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CLSPN_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.029899 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

MYPT2_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.010465 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	707	Shared Neighborhood Hits	58
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

NIN_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.055882 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	1416	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

SPTB1_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.031219 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	541	Shared Neighborhood Hits	64
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

KI21B_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.035717 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	1017	Shared Neighborhood Hits	70
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

NFH_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.017384 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	2247	Shared Neighborhood Hits	80
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OPHN1_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.005535 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

AL2S8_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.014556 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

ATRX_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.025317 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	68
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CJ078_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.021822 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	559	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CLSPN_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.012968 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

FA44A_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.047087 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

NFL_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.025412 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	695	Shared Neighborhood Hits	68
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PEX5_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.009167 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PININ_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.034384 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	753	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PME17_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.008501 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

SLK_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.012762 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	1798	Shared Neighborhood Hits	84
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TXLNB_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.036736 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	912	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ANR45_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.164730 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.123716 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

BICD2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.059319 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	864	Shared Neighborhood Hits	81
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BPA1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.051031 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.052239 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	1369	Shared Neighborhood Hits	87
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.053598 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	1480	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CAF1A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.066364 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	750	Shared Neighborhood Hits	77
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCD11_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.050785 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	822	Shared Neighborhood Hits	76
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD39_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.053128 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	868	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.052013 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	1026	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD46_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.052425 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	1430	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.053870 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	86
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD62_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.054249 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	631	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CE152_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.050766 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	976	Shared Neighborhood Hits	74
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.054109 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	1553	Shared Neighborhood Hits	84
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPF_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.060265 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	1932	Shared Neighborhood Hits	100
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF060_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.054534 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CI093_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.050948 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	1088	Shared Neighborhood Hits	82
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.053175 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	1432	Shared Neighborhood Hits	83
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CJ118_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.058466 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	937	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CK5P2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.050386 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	1151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

COVA1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.051857 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	53
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

CP135_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.050477 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	1290	Shared Neighborhood Hits	81
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.050614 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	1278	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CTGE5_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.054649 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	800	Shared Neighborhood Hits	78
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CTGE5_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.050257 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	928	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CYLN2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.051748 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	1004	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DESP_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.052835 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	90
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EEA1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.050469 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	1637	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FLIP1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.062642 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.054102 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	1176	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GCC2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.061038 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	1619	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA5_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.055504 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	1168	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGB1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.063984 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	2297	Shared Neighborhood Hits	107
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HMMR_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.061965 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.055109 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	1178	Shared Neighborhood Hits	81
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HS12B_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.091869 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

IF3A_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.050643 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	871	Shared Neighborhood Hits	72
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

IFT74_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.052185 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	949	Shared Neighborhood Hits	79
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.050908 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	939	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

KTN1_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.053658 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	1324	Shared Neighborhood Hits	87
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LIPA1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.050020 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	1294	Shared Neighborhood Hits	78
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LUZP1_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.050688 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	940	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MFAP1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.057485 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MY18B_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.061765 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	1299	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH14_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.069978 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	995	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH14_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.069772 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	1225	Shared Neighborhood Hits	89
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYO10_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.053311 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	920	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO5A_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.057735 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	1092	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.059274 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	1117	Shared Neighborhood Hits	78
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5C_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.062572 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	1206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.060507 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	727	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.058580 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	586	Shared Neighborhood Hits	61
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NUF2_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.050406 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	661	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

RABE1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.051842 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	1105	Shared Neighborhood Hits	78
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RAD50_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.057117 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	1317	Shared Neighborhood Hits	92
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.052326 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	1366	Shared Neighborhood Hits	87
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.055213 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	1584	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.052024 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	1433	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

REST_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.058095 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	1605	Shared Neighborhood Hits	93
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.062936 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	1506	Shared Neighborhood Hits	90
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RPGR1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.052307 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	713	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SFR12_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.063668 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SM1L2_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.055036 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	918	Shared Neighborhood Hits	76
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC1A_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.051234 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.052587 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	1384	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.051132 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	83
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC3_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.058551 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	1186	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.058420 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	1187	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SYCP1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.067120 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	1313	Shared Neighborhood Hits	93
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE2_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.052383 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	1323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TACC1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.052195 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	62
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TACC1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.051408 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	667	Shared Neighborhood Hits	65
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.054372 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	856	Shared Neighborhood Hits	68
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TACC2_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.053138 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	774	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TAF7_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.051052 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

TNNT2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.052777 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	433	Shared Neighborhood Hits	54
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TPM2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.053804 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	677	Shared Neighborhood Hits	68
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPM2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.053050 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	676	Shared Neighborhood Hits	69
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TPR_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.050701 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	1921	Shared Neighborhood Hits	86
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRDN_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.056519 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	542	Shared Neighborhood Hits	56
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

XE7_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.050471 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	738	Shared Neighborhood Hits	76
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

Hits sorted by NC score

HS74L_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_MOUSE
NC score	0.989296 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	77
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS105_MOUSE
NC score	0.982204 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	40
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

HSP74_HUMAN
NC score	0.979285 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	154	Shared Neighborhood Hits	47
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

HS105_HUMAN
NC score	0.976404 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	209	Shared Neighborhood Hits	51
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HSP74_MOUSE
NC score	0.971669 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	257	Shared Neighborhood Hits	77
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HSP76_HUMAN
NC score	0.903248 (rank : 7)	θ value	1.35953e-72 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	43
SwissProt Accessions	P17066, Q8IYK7, Q9BT95	Gene names	HSPA6, HSP70B'
Domain Architecture
Description	Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B').

GRP75_MOUSE
NC score	0.902166 (rank : 8)	θ value	4.53632e-60 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	P38647, Q9CQ05	Gene names	Hspa9a, Grp75, Hsp74, Hspa9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (P66 MOT) (Mortalin).

HS70B_MOUSE
NC score	0.901311 (rank : 9)	θ value	1.22964e-73 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	P17879, Q61689, Q925V6	Gene names	Hspa1b, Hcp70.1, Hsp70-1, Hsp70a1, Hspa1
Domain Architecture
Description	Heat shock 70 kDa protein 1B (HSP70.1).

HS70A_MOUSE
NC score	0.901294 (rank : 10)	θ value	1.22964e-73 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	35
SwissProt Accessions	Q61696, Q61697, Q7TQD8, Q9QWJ5	Gene names	Hspa1a, Hsp70-3, Hsp70A1
Domain Architecture	No domain graphic available
Description	Heat shock 70 kDa protein 1A (Heat shock 70 kDa protein 3) (HSP70.3) (Hsp68).

HSP71_HUMAN
NC score	0.901159 (rank : 11)	θ value	1.89707e-74 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	P08107, P19790, Q9UQL9, Q9UQM0	Gene names	HSPA1A, HSPA1
Domain Architecture
Description	Heat shock 70 kDa protein 1 (HSP70.1) (HSP70-1/HSP70-2).

HS70L_MOUSE
NC score	0.901134 (rank : 12)	θ value	1.89707e-74 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	24
SwissProt Accessions	P16627, O88686, Q61693	Gene names	Hspa1l, Hsc70t
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70).

GRP75_HUMAN
NC score	0.901015 (rank : 13)	θ value	7.73779e-60 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	P38646, P30036, P31932, Q9BWB7	Gene names	HSPA9B, GRP75, HSPA9
Domain Architecture
Description	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75) (Peptide-binding protein 74) (PBP74) (Mortalin) (MOT).

OXRP_HUMAN
NC score	0.900607 (rank : 14)	θ value	1.44917e-82 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	544	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

HS70L_HUMAN
NC score	0.900461 (rank : 15)	θ value	1.71583e-75 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	P34931, O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1	Gene names	HSPA1L
Domain Architecture
Description	Heat shock 70 kDa protein 1L (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom).

HSP7C_MOUSE
NC score	0.899703 (rank : 16)	θ value	1.7756e-72 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_HUMAN
NC score	0.899171 (rank : 17)	θ value	1.7756e-72 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	48
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP72_HUMAN
NC score	0.898492 (rank : 18)	θ value	2.3998e-69 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	42
SwissProt Accessions	P54652, Q15508, Q9UE78	Gene names	HSPA2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2).

HSP72_MOUSE
NC score	0.897645 (rank : 19)	θ value	5.34618e-69 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	P17156	Gene names	Hspa2, Hcp70.2, Hsp70-2
Domain Architecture
Description	Heat shock-related 70 kDa protein 2 (Heat shock protein 70.2).

GRP78_HUMAN
NC score	0.896740 (rank : 20)	θ value	1.71981e-67 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	218	Shared Neighborhood Hits	56
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.896654 (rank : 21)	θ value	1.31681e-67 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	216	Shared Neighborhood Hits	56
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

STCH_HUMAN
NC score	0.890983 (rank : 22)	θ value	1.57e-36 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P48723, Q8NE40	Gene names	STCH
Domain Architecture
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

STCH_MOUSE
NC score	0.886232 (rank : 23)	θ value	4.27553e-34 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BM72, Q3TII6, Q9D1X5	Gene names	Stch
Domain Architecture	No domain graphic available
Description	Stress 70 protein chaperone microsome-associated 60 kDa protein precursor (Microsomal stress 70 protein ATPase core).

ANR45_HUMAN
NC score	0.164730 (rank : 24)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	201	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
NC score	0.123716 (rank : 25)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	204	Shared Neighborhood Hits	14
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

HS12B_MOUSE
NC score	0.091869 (rank : 26)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CZJ2	Gene names	Hspa12b
Domain Architecture
Description	Heat shock 70 kDa protein 12B.

CCD91_HUMAN
NC score	0.086039 (rank : 27)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	868	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

MYH11_HUMAN
NC score	0.083338 (rank : 28)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	1806	Shared Neighborhood Hits	101
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH10_HUMAN
NC score	0.083130 (rank : 29)	θ value	0.00228821 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	1620	Shared Neighborhood Hits	98
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_HUMAN
NC score	0.082781 (rank : 30)	θ value	0.0431538 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	1762	Shared Neighborhood Hits	101
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH10_MOUSE
NC score	0.082122 (rank : 31)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	1612	Shared Neighborhood Hits	98
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_MOUSE
NC score	0.078994 (rank : 32)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	1829	Shared Neighborhood Hits	101
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ENKUR_MOUSE
NC score	0.078883 (rank : 33)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q6SP97	Gene names
Domain Architecture	No domain graphic available
Description	Enkurin.

MYH11_MOUSE
NC score	0.078373 (rank : 34)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	1777	Shared Neighborhood Hits	99
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH8_MOUSE
NC score	0.077666 (rank : 35)	θ value	0.00035302 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	1600	Shared Neighborhood Hits	94
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH2_HUMAN
NC score	0.075603 (rank : 36)	θ value	0.0148317 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	1491	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH6_MOUSE
NC score	0.075367 (rank : 37)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	1501	Shared Neighborhood Hits	94
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
NC score	0.075187 (rank : 38)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	1559	Shared Neighborhood Hits	94
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

IF2P_HUMAN
NC score	0.074860 (rank : 39)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	889	Shared Neighborhood Hits	85
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MYH4_HUMAN
NC score	0.074275 (rank : 40)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	1377	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH1_HUMAN
NC score	0.074273 (rank : 41)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	1478	Shared Neighborhood Hits	90
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH4_MOUSE
NC score	0.074090 (rank : 42)	θ value	0.00665767 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	1476	Shared Neighborhood Hits	91
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
NC score	0.073585 (rank : 43)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	1610	Shared Neighborhood Hits	92
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH13_HUMAN
NC score	0.073149 (rank : 44)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	1504	Shared Neighborhood Hits	92
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH1_MOUSE
NC score	0.072900 (rank : 45)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	1461	Shared Neighborhood Hits	89
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

SYCP1_MOUSE
NC score	0.072710 (rank : 46)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	1456	Shared Neighborhood Hits	95
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MYH6_HUMAN
NC score	0.071665 (rank : 47)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	1426	Shared Neighborhood Hits	91
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

TACC3_MOUSE
NC score	0.070079 (rank : 48)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	607	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

MYH14_HUMAN
NC score	0.069978 (rank : 49)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	995	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH3_HUMAN
NC score	0.069934 (rank : 50)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	1660	Shared Neighborhood Hits	97
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH14_MOUSE
NC score	0.069772 (rank : 51)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	1225	Shared Neighborhood Hits	89
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYO5B_HUMAN
NC score	0.069478 (rank : 52)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	911	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

CCD91_MOUSE
NC score	0.068550 (rank : 53)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	699	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

GOGA4_HUMAN
NC score	0.067737 (rank : 54)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	2034	Shared Neighborhood Hits	99
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SYCP1_HUMAN
NC score	0.067120 (rank : 55)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	1313	Shared Neighborhood Hits	93
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CAF1A_HUMAN
NC score	0.066364 (rank : 56)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	750	Shared Neighborhood Hits	77
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

HOOK1_HUMAN
NC score	0.064960 (rank : 57)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	942	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

TACC3_HUMAN
NC score	0.064823 (rank : 58)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	779	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CJ118_MOUSE
NC score	0.064754 (rank : 59)	θ value	0.000158464 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	1132	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

GOGB1_HUMAN
NC score	0.063984 (rank : 60)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	2297	Shared Neighborhood Hits	107
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GOGA4_MOUSE
NC score	0.063790 (rank : 61)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	1939	Shared Neighborhood Hits	96
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

TRHY_HUMAN
NC score	0.063694 (rank : 62)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	1385	Shared Neighborhood Hits	91
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

SFR12_HUMAN
NC score	0.063668 (rank : 63)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

REST_MOUSE
NC score	0.062936 (rank : 64)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	1506	Shared Neighborhood Hits	90
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

FLIP1_HUMAN
NC score	0.062642 (rank : 65)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	91
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYO5C_HUMAN
NC score	0.062572 (rank : 66)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	1206	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

LIPA2_MOUSE
NC score	0.062151 (rank : 67)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	1282	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

HMMR_HUMAN
NC score	0.061965 (rank : 68)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MY18B_HUMAN
NC score	0.061765 (rank : 69)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	1299	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

GCC2_MOUSE
NC score	0.061038 (rank : 70)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	1619	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MYO6_HUMAN
NC score	0.060507 (rank : 71)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	727	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

CENPF_HUMAN
NC score	0.060265 (rank : 72)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	1932	Shared Neighborhood Hits	100
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

EEA1_HUMAN
NC score	0.059980 (rank : 73)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	1796	Shared Neighborhood Hits	93
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

MY18A_HUMAN
NC score	0.059656 (rank : 74)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	1929	Shared Neighborhood Hits	90
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

BICD2_MOUSE
NC score	0.059319 (rank : 75)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	864	Shared Neighborhood Hits	81
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

MYO5A_MOUSE
NC score	0.059274 (rank : 76)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	1117	Shared Neighborhood Hits	78
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RBP24_HUMAN
NC score	0.058944 (rank : 77)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	1559	Shared Neighborhood Hits	87
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.058926 (rank : 78)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	1558	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MY18A_MOUSE
NC score	0.058767 (rank : 79)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	1989	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYO6_MOUSE
NC score	0.058580 (rank : 80)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	586	Shared Neighborhood Hits	61
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

SMC3_HUMAN
NC score	0.058551 (rank : 81)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	1186	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CJ118_HUMAN
NC score	0.058466 (rank : 82)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	937	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

SMC3_MOUSE
NC score	0.058420 (rank : 83)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	1187	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

REST_HUMAN
NC score	0.058095 (rank : 84)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	1605	Shared Neighborhood Hits	93
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

LIPA2_HUMAN
NC score	0.057989 (rank : 85)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	1044	Shared Neighborhood Hits	81
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

MYO5A_HUMAN
NC score	0.057735 (rank : 86)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	1092	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MFAP1_HUMAN
NC score	0.057485 (rank : 87)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	41
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

HOOK1_MOUSE
NC score	0.057284 (rank : 88)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

RAD50_HUMAN
NC score	0.057117 (rank : 89)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	1317	Shared Neighborhood Hits	92
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TRIPB_HUMAN
NC score	0.056798 (rank : 90)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	1587	Shared Neighborhood Hits	99
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ERC2_MOUSE
NC score	0.056734 (rank : 91)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	1166	Shared Neighborhood Hits	87
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

TRDN_HUMAN
NC score	0.056519 (rank : 92)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	542	Shared Neighborhood Hits	56
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ERC2_HUMAN
NC score	0.056265 (rank : 93)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	1156	Shared Neighborhood Hits	86
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

NIN_HUMAN
NC score	0.055882 (rank : 94)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	1416	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CENPE_HUMAN
NC score	0.055703 (rank : 95)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GOGA5_HUMAN
NC score	0.055504 (rank : 96)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	1168	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SMC4_HUMAN
NC score	0.055443 (rank : 97)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	937	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

RB6I2_HUMAN
NC score	0.055213 (rank : 98)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	1584	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

HMMR_MOUSE
NC score	0.055109 (rank : 99)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	1178	Shared Neighborhood Hits	81
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SM1L2_MOUSE
NC score	0.055036 (rank : 100)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	918	Shared Neighborhood Hits	76
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

CTGE5_HUMAN
NC score	0.054649 (rank : 101)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	800	Shared Neighborhood Hits	78
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

CF060_HUMAN
NC score	0.054534 (rank : 102)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	1270	Shared Neighborhood Hits	84
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

TACC2_HUMAN
NC score	0.054372 (rank : 103)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	856	Shared Neighborhood Hits	68
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

CCD62_HUMAN
NC score	0.054249 (rank : 104)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	631	Shared Neighborhood Hits	68
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CE290_HUMAN
NC score	0.054109 (rank : 105)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	1553	Shared Neighborhood Hits	84
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

FLIP1_MOUSE
NC score	0.054102 (rank : 106)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	1176	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LUZP1_HUMAN
NC score	0.054052 (rank : 107)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	739	Shared Neighborhood Hits	71
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

CCD46_MOUSE
NC score	0.053870 (rank : 108)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	86
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TPM2_HUMAN
NC score	0.053804 (rank : 109)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	677	Shared Neighborhood Hits	68
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

TMF1_HUMAN
NC score	0.053796 (rank : 110)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	987	Shared Neighborhood Hits	81
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

KTN1_MOUSE
NC score	0.053658 (rank : 111)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	1324	Shared Neighborhood Hits	87
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

BPAEA_MOUSE
NC score	0.053598 (rank : 112)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	1480	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MYO10_HUMAN
NC score	0.053311 (rank : 113)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	920	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

CING_MOUSE
NC score	0.053175 (rank : 114)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	1432	Shared Neighborhood Hits	83
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

TACC2_MOUSE
NC score	0.053138 (rank : 115)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	774	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

CCD39_HUMAN
NC score	0.053128 (rank : 116)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	868	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

TPM2_MOUSE
NC score	0.053050 (rank : 117)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	676	Shared Neighborhood Hits	69
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

DESP_HUMAN
NC score	0.052835 (rank : 118)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	1470	Shared Neighborhood Hits	90
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

TNNT2_HUMAN
NC score	0.052777 (rank : 119)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	433	Shared Neighborhood Hits	54
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

KTN1_HUMAN
NC score	0.052710 (rank : 120)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	1197	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

SMC1A_MOUSE
NC score	0.052587 (rank : 121)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	1384	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CCD46_HUMAN
NC score	0.052425 (rank : 122)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	1430	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SYNE2_HUMAN
NC score	0.052383 (rank : 123)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	1323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

RAD50_MOUSE
NC score	0.052326 (rank : 124)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	1366	Shared Neighborhood Hits	87
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RPGR1_MOUSE
NC score	0.052307 (rank : 125)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	713	Shared Neighborhood Hits	70
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

BPAEA_HUMAN
NC score	0.052239 (rank : 126)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	1369	Shared Neighborhood Hits	87
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TACC1_HUMAN
NC score	0.052195 (rank : 127)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	597	Shared Neighborhood Hits	62
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

IFT74_HUMAN
NC score	0.052185 (rank : 128)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	949	Shared Neighborhood Hits	79
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

RB6I2_MOUSE
NC score	0.052024 (rank : 129)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	1433	Shared Neighborhood Hits	86
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CCD39_MOUSE
NC score	0.052013 (rank : 130)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	1026	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

COVA1_HUMAN
NC score	0.051857 (rank : 131)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	53
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

RABE1_MOUSE
NC score	0.051842 (rank : 132)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	1105	Shared Neighborhood Hits	78
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CYLN2_HUMAN
NC score	0.051748 (rank : 133)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	1004	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

ASPH_HUMAN
NC score	0.051565 (rank : 134)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	158	Shared Neighborhood Hits	17
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

TACC1_MOUSE
NC score	0.051408 (rank : 135)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	667	Shared Neighborhood Hits	65
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

SMC1A_HUMAN
NC score	0.051234 (rank : 136)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	1346	Shared Neighborhood Hits	84
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

KIF23_HUMAN
NC score	0.051180 (rank : 137)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	618	Shared Neighborhood Hits	72
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

SMC2_HUMAN
NC score	0.051132 (rank : 138)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	1405	Shared Neighborhood Hits	83
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TAF7_MOUSE
NC score	0.051052 (rank : 139)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	217	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1C0	Gene names	Taf7, Taf2f
Domain Architecture
Description	Transcription initiation factor TFIID subunit 7 (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55).

BPA1_MOUSE
NC score	0.051031 (rank : 140)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CI093_HUMAN
NC score	0.050948 (rank : 141)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	1088	Shared Neighborhood Hits	82
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

IFT74_MOUSE
NC score	0.050908 (rank : 142)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	939	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CCD11_HUMAN
NC score	0.050785 (rank : 143)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	822	Shared Neighborhood Hits	76
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CE152_HUMAN
NC score	0.050766 (rank : 144)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	976	Shared Neighborhood Hits	74
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

TPR_HUMAN
NC score	0.050701 (rank : 145)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	1921	Shared Neighborhood Hits	86
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

LUZP1_MOUSE
NC score	0.050688 (rank : 146)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	940	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

IF3A_MOUSE
NC score	0.050643 (rank : 147)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	871	Shared Neighborhood Hits	72
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

CP135_MOUSE
NC score	0.050614 (rank : 148)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	1278	Shared Neighborhood Hits	81
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP135_HUMAN
NC score	0.050477 (rank : 149)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	1290	Shared Neighborhood Hits	81
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

XE7_HUMAN
NC score	0.050471 (rank : 150)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	738	Shared Neighborhood Hits	76
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

EEA1_MOUSE
NC score	0.050469 (rank : 151)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	1637	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

NUF2_HUMAN
NC score	0.050406 (rank : 152)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	661	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

CK5P2_MOUSE
NC score	0.050386 (rank : 153)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	1151	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CTGE5_MOUSE
NC score	0.050257 (rank : 154)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	928	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

LIPA1_HUMAN
NC score	0.050020 (rank : 155)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	1294	Shared Neighborhood Hits	78
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

SMC4_MOUSE
NC score	0.049725 (rank : 156)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	830	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

HOME2_MOUSE
NC score	0.049587 (rank : 157)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	882	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

HOOK2_HUMAN
NC score	0.049108 (rank : 158)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	714	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

SYNE1_HUMAN
NC score	0.048120 (rank : 159)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	1484	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TPM1_HUMAN
NC score	0.047687 (rank : 160)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	716	Shared Neighborhood Hits	76
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
NC score	0.047605 (rank : 161)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	729	Shared Neighborhood Hits	77
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

FA44A_HUMAN
NC score	0.047087 (rank : 162)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	280	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

PCNT_MOUSE
NC score	0.045657 (rank : 163)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	1207	Shared Neighborhood Hits	80
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CK5P2_HUMAN
NC score	0.045402 (rank : 164)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	1433	Shared Neighborhood Hits	85
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

NFM_HUMAN
NC score	0.044931 (rank : 165)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	1328	Shared Neighborhood Hits	91
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

HAP1_MOUSE
NC score	0.039235 (rank : 166)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	388	Shared Neighborhood Hits	51
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

RYR1_HUMAN
NC score	0.038639 (rank : 167)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

K0256_HUMAN
NC score	0.037933 (rank : 168)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q93073, Q8N767	Gene names	KIAA0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

MRCKA_HUMAN
NC score	0.036916 (rank : 169)	θ value	1.43324e-05 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	1999	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

TXLNB_HUMAN
NC score	0.036736 (rank : 170)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	912	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

C8AP2_MOUSE
NC score	0.035934 (rank : 171)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

KI21B_HUMAN
NC score	0.035717 (rank : 172)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	1017	Shared Neighborhood Hits	70
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

TTC1_HUMAN
NC score	0.035455 (rank : 173)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ANR12_HUMAN
NC score	0.035288 (rank : 174)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	1081	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

PININ_HUMAN
NC score	0.034384 (rank : 175)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	753	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

LEO1_HUMAN
NC score	0.033567 (rank : 176)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	958	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PKHA5_HUMAN
NC score	0.031628 (rank : 177)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	455	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

MOES_HUMAN
NC score	0.031401 (rank : 178)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	892	Shared Neighborhood Hits	69
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

SPTB1_HUMAN
NC score	0.031219 (rank : 179)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	541	Shared Neighborhood Hits	64
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

KI21B_MOUSE
NC score	0.030879 (rank : 180)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

PDC10_MOUSE
NC score	0.030633 (rank : 181)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE70, Q9DAR3, Q9WV43	Gene names	Pdcd10, Tfar15
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 10 (TF-1 cell apoptosis-related protein 15).

PDC10_HUMAN
NC score	0.030584 (rank : 182)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BUL8, O14811	Gene names	PDCD10, CCM3, TFAR15
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 10 (TF-1 cell apoptosis-related protein 15) (Cerebral cavernous malformations 3 protein).

TSKS_HUMAN
NC score	0.030151 (rank : 183)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	220	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

CLSPN_HUMAN
NC score	0.029899 (rank : 184)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	433	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CN130_HUMAN
NC score	0.029546 (rank : 185)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

ROCK2_MOUSE
NC score	0.028113 (rank : 186)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	2072	Shared Neighborhood Hits	85
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ROCK2_HUMAN
NC score	0.026929 (rank : 187)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	2073	Shared Neighborhood Hits	88
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

NFL_MOUSE
NC score	0.025412 (rank : 188)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	695	Shared Neighborhood Hits	68
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

ATRX_HUMAN
NC score	0.025317 (rank : 189)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	842	Shared Neighborhood Hits	68
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RP1L1_MOUSE
NC score	0.025196 (rank : 190)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SPTN5_HUMAN
NC score	0.024385 (rank : 191)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	674	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

AL2S8_HUMAN
NC score	0.022149 (rank : 192)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N187, Q8ND29, Q8WXC0, Q96J78, Q96Q38, Q96Q39, Q9H712	Gene names	ALS2CR8, CARF
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24).

CILP1_HUMAN
NC score	0.021931 (rank : 193)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CJ078_MOUSE
NC score	0.021822 (rank : 194)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	559	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

2ACA_HUMAN
NC score	0.021704 (rank : 195)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	26
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

CILP1_MOUSE
NC score	0.020916 (rank : 196)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

TRI44_HUMAN
NC score	0.020457 (rank : 197)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

C8AP2_HUMAN
NC score	0.019993 (rank : 198)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	548	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

RBP22_HUMAN
NC score	0.018842 (rank : 199)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

TITIN_HUMAN
NC score	0.018108 (rank : 200)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	2923	Shared Neighborhood Hits	82
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

RGPD8_HUMAN
NC score	0.018014 (rank : 201)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	27
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

PMS1_HUMAN
NC score	0.017882 (rank : 202)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	9
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

NFH_MOUSE
NC score	0.017384 (rank : 203)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	2247	Shared Neighborhood Hits	80
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PPRB_HUMAN
NC score	0.015814 (rank : 204)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	311	Shared Neighborhood Hits	8
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SETB1_HUMAN
NC score	0.015684 (rank : 205)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	11
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

ZN638_MOUSE
NC score	0.015116 (rank : 206)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	318	Shared Neighborhood Hits	31
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

SETB1_MOUSE
NC score	0.014822 (rank : 207)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	15
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

AL2S8_MOUSE
NC score	0.014556 (rank : 208)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI4	Gene names	Als2cr8, Carf
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein homolog (Calcium-response factor) (CaRF).

TRM6_HUMAN
NC score	0.013629 (rank : 209)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJA5, Q76P92, Q9BQV5, Q9ULR7	Gene names	TRM6, KIAA1153
Domain Architecture	No domain graphic available
Description	tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 (tRNA(m1A58)-methyltransferase subunit TRM6) (tRNA(m1A58)MTase subunit TRM6).

CLSPN_MOUSE
NC score	0.012968 (rank : 210)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	292	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

SLK_MOUSE
NC score	0.012762 (rank : 211)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	1798	Shared Neighborhood Hits	84
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

NP1L2_MOUSE
NC score	0.011000 (rank : 212)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	P51860	Gene names	Nap1l2, Bpx
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

MYPT2_HUMAN
NC score	0.010465 (rank : 213)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	707	Shared Neighborhood Hits	58
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

FINC_MOUSE
NC score	0.010284 (rank : 214)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FINC_HUMAN
NC score	0.010232 (rank : 215)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	302	Shared Neighborhood Hits	5
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

MYST4_MOUSE
NC score	0.009964 (rank : 216)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PEX5_HUMAN
NC score	0.009167 (rank : 217)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

SMAL1_MOUSE
NC score	0.008964 (rank : 218)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

TGM5_HUMAN
NC score	0.008930 (rank : 219)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43548, O43549, Q9UEZ4	Gene names	TGM5, TGMX
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5) (Transglutaminase X) (TGase X) (TGX) (TG(X)).

PME17_MOUSE
NC score	0.008501 (rank : 220)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

OPHN1_MOUSE
NC score	0.005535 (rank : 221)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

STK4_HUMAN
NC score	0.004559 (rank : 222)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	870	Shared Neighborhood Hits	13
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

STK4_MOUSE
NC score	0.004298 (rank : 223)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	873	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).