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Network neighborhood for query Sequence : DLEC1_HUMAN

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DLEC1_HUMAN
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DLEC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

DLEC1_MOUSE
θ value	0 (rank : 2)	NC score	0.961761 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BLA1	Gene names	Dlec1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 homolog.

CP250_HUMAN
θ value	0.0252991 (rank : 3)	NC score	0.030929 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	1805	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NIN_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.031992 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	1416	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CX022_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.096210 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

TAF3_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.048869 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	463	Shared Neighborhood Hits	10
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRHY_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.031759 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	1385	Shared Neighborhood Hits	21
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CTGE5_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.027364 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	928	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DNL1_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.035366 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

FA13C_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.031535 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

MRE11_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.050791 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

NPHN_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.017248 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

UBAP1_HUMAN
θ value	1.38821 (rank : 13)	NC score	0.040284 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

LETM1_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.034297 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

PRP40_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.038525 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	442	Shared Neighborhood Hits	13
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

UB7I1_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.030301 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

CCD11_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.031338 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	498	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

LYSM3_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.033240 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3D4, Q5H9U0, Q6PEK0, Q9NTE9	Gene names	LYSMD3
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 3.

PIBF1_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.022519 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	1041	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

YETS2_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.026028 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CCD46_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.020172 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	1430	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MRE11_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.045473 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

HSP74_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.010820 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

ATP7B_MOUSE
θ value	5.27518 (rank : 24)	NC score	0.012331 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

ATX7_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.019830 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CAS1_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.035902 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P19228	Gene names	Csn1s1, Csn1, Csna
Domain Architecture
Description	Alpha-s1-casein precursor.

CD22_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.010054 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

PRP40_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.031780 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	447	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

STK10_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.009043 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	2132	Shared Neighborhood Hits	23
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TSP1_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.006234 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	389	Shared Neighborhood Hits	2
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ANKR5_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.010217 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

DOT1L_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.021863 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GOGA6_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.021748 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	1007	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

PBX4_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.009166 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NE9, Q8CFL2, Q99NE8	Gene names	Pbx4
Domain Architecture
Description	Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4).

SYNE1_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.017045 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TRAK1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.018585 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	660	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

AMOL2_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.016213 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	591	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ASPP1_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.009697 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	956	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ESPL1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.013154 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

LRRK2_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.002029 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	1359	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

SLK_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.006907 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	1775	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.007062 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	1798	Shared Neighborhood Hits	17
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SYN3_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.009350 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

ZCRB1_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.008698 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	230	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBF4, Q6PJX0	Gene names	ZCRB1
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 snRNP 31 kDa protein) (U11/U12-31K).

Hits sorted by NC score

DLEC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y238, Q9NSW0, Q9NTG5	Gene names	DLEC1, DLC1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1).

DLEC1_MOUSE
NC score	0.961761 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BLA1	Gene names	Dlec1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 homolog.

CX022_HUMAN
NC score	0.096210 (rank : 3)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZTR5, Q5JRM8, Q8N6X8	Gene names	CXorf22
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf22.

MRE11_HUMAN
NC score	0.050791 (rank : 4)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

TAF3_MOUSE
NC score	0.048869 (rank : 5)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	463	Shared Neighborhood Hits	10
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

MRE11_MOUSE
NC score	0.045473 (rank : 6)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	137	Shared Neighborhood Hits	7
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

UBAP1_HUMAN
NC score	0.040284 (rank : 7)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

PRP40_HUMAN
NC score	0.038525 (rank : 8)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	442	Shared Neighborhood Hits	13
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

CAS1_MOUSE
NC score	0.035902 (rank : 9)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P19228	Gene names	Csn1s1, Csn1, Csna
Domain Architecture
Description	Alpha-s1-casein precursor.

DNL1_HUMAN
NC score	0.035366 (rank : 10)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

LETM1_MOUSE
NC score	0.034297 (rank : 11)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

LYSM3_HUMAN
NC score	0.033240 (rank : 12)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z3D4, Q5H9U0, Q6PEK0, Q9NTE9	Gene names	LYSMD3
Domain Architecture	No domain graphic available
Description	LysM and putative peptidoglycan-binding domain-containing protein 3.

NIN_HUMAN
NC score	0.031992 (rank : 13)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	1416	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PRP40_MOUSE
NC score	0.031780 (rank : 14)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	447	Shared Neighborhood Hits	12
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

TRHY_HUMAN
NC score	0.031759 (rank : 15)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	1385	Shared Neighborhood Hits	21
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

FA13C_MOUSE
NC score	0.031535 (rank : 16)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DBR2	Gene names	Fam13c1
Domain Architecture	No domain graphic available
Description	Protein FAM13C1.

CCD11_MOUSE
NC score	0.031338 (rank : 17)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	498	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CP250_HUMAN
NC score	0.030929 (rank : 18)	θ value	0.0252991 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	1805	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

UB7I1_HUMAN
NC score	0.030301 (rank : 19)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

CTGE5_MOUSE
NC score	0.027364 (rank : 20)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	928	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

YETS2_MOUSE
NC score	0.026028 (rank : 21)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	278	Shared Neighborhood Hits	5
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

PIBF1_HUMAN
NC score	0.022519 (rank : 22)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	1041	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

DOT1L_HUMAN
NC score	0.021863 (rank : 23)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	660	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GOGA6_HUMAN
NC score	0.021748 (rank : 24)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	1007	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CCD46_HUMAN
NC score	0.020172 (rank : 25)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	1430	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ATX7_MOUSE
NC score	0.019830 (rank : 26)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	328	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

TRAK1_HUMAN
NC score	0.018585 (rank : 27)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	660	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

NPHN_HUMAN
NC score	0.017248 (rank : 28)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	362	Shared Neighborhood Hits	3
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SYNE1_HUMAN
NC score	0.017045 (rank : 29)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AMOL2_MOUSE
NC score	0.016213 (rank : 30)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	591	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

ESPL1_HUMAN
NC score	0.013154 (rank : 31)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

ATP7B_MOUSE
NC score	0.012331 (rank : 32)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q64446	Gene names	Atp7b, Wnd
Domain Architecture
Description	Copper-transporting ATPase 2 (EC 3.6.3.4) (Copper pump 2) (Wilson disease-associated protein homolog).

HSP74_HUMAN
NC score	0.010820 (rank : 33)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

ANKR5_HUMAN
NC score	0.010217 (rank : 34)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

CD22_HUMAN
NC score	0.010054 (rank : 35)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

ASPP1_HUMAN
NC score	0.009697 (rank : 36)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	956	Shared Neighborhood Hits	12
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

SYN3_MOUSE
NC score	0.009350 (rank : 37)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZP2	Gene names	Syn3
Domain Architecture	No domain graphic available
Description	Synapsin-3 (Synapsin III).

PBX4_MOUSE
NC score	0.009166 (rank : 38)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NE9, Q8CFL2, Q99NE8	Gene names	Pbx4
Domain Architecture
Description	Pre-B-cell leukemia transcription factor 4 (Homeobox protein PBX4).

STK10_MOUSE
NC score	0.009043 (rank : 39)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	2132	Shared Neighborhood Hits	23
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ZCRB1_HUMAN
NC score	0.008698 (rank : 40)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	230	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TBF4, Q6PJX0	Gene names	ZCRB1
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (U11/U12 snRNP 31 kDa protein) (U11/U12-31K).

SLK_MOUSE
NC score	0.007062 (rank : 41)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	1798	Shared Neighborhood Hits	17
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

SLK_HUMAN
NC score	0.006907 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	1775	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

TSP1_HUMAN
NC score	0.006234 (rank : 43)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	389	Shared Neighborhood Hits	2
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

LRRK2_MOUSE
NC score	0.002029 (rank : 44)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	1359	Shared Neighborhood Hits	5
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).