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Network neighborhood for query Sequence : OTOF_MOUSE

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OTOF_MOUSE
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DYSF_HUMAN
θ value	0 (rank : 1)	NC score	0.914405 (rank : 4)
Query Neighborhood Hits	196	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
θ value	0 (rank : 2)	NC score	0.910911 (rank : 5)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
θ value	0 (rank : 3)	NC score	0.918418 (rank : 3)
Query Neighborhood Hits	196	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

OTOF_HUMAN
θ value	0 (rank : 4)	NC score	0.993605 (rank : 2)
Query Neighborhood Hits	196	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	196	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

RASL1_HUMAN
θ value	2.28291e-11 (rank : 6)	NC score	0.438515 (rank : 6)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	98
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	3.29651e-10 (rank : 7)	NC score	0.424086 (rank : 7)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

PCLO_MOUSE
θ value	4.0297e-08 (rank : 8)	NC score	0.284734 (rank : 50)
Query Neighborhood Hits	196	Target Neighborhood Hits	2275	Shared Neighborhood Hits	149
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASL2_HUMAN
θ value	5.81887e-07 (rank : 9)	NC score	0.410349 (rank : 8)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

PCLO_HUMAN
θ value	3.77169e-06 (rank : 10)	NC score	0.299179 (rank : 46)
Query Neighborhood Hits	196	Target Neighborhood Hits	2046	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

KPCB_MOUSE
θ value	4.92598e-06 (rank : 11)	NC score	0.125187 (rank : 113)
Query Neighborhood Hits	196	Target Neighborhood Hits	1117	Shared Neighborhood Hits	103
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
θ value	1.09739e-05 (rank : 12)	NC score	0.123565 (rank : 116)
Query Neighborhood Hits	196	Target Neighborhood Hits	1121	Shared Neighborhood Hits	103
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT5_MOUSE
θ value	1.09739e-05 (rank : 13)	NC score	0.379042 (rank : 18)
Query Neighborhood Hits	196	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

ITSN2_MOUSE
θ value	1.43324e-05 (rank : 14)	NC score	0.170073 (rank : 101)
Query Neighborhood Hits	196	Target Neighborhood Hits	1371	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KPCG_MOUSE
θ value	1.87187e-05 (rank : 15)	NC score	0.131066 (rank : 110)
Query Neighborhood Hits	196	Target Neighborhood Hits	1123	Shared Neighborhood Hits	102
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCA_HUMAN
θ value	2.44474e-05 (rank : 16)	NC score	0.124936 (rank : 114)
Query Neighborhood Hits	196	Target Neighborhood Hits	1070	Shared Neighborhood Hits	105
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_HUMAN
θ value	2.44474e-05 (rank : 17)	NC score	0.130894 (rank : 111)
Query Neighborhood Hits	196	Target Neighborhood Hits	1126	Shared Neighborhood Hits	102
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT1_HUMAN
θ value	2.44474e-05 (rank : 18)	NC score	0.372917 (rank : 25)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	2.44474e-05 (rank : 19)	NC score	0.372907 (rank : 26)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT2_HUMAN
θ value	2.44474e-05 (rank : 20)	NC score	0.369253 (rank : 32)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	2.44474e-05 (rank : 21)	NC score	0.370171 (rank : 31)
Query Neighborhood Hits	196	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_HUMAN
θ value	2.44474e-05 (rank : 22)	NC score	0.376209 (rank : 20)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT7_MOUSE
θ value	2.44474e-05 (rank : 23)	NC score	0.372565 (rank : 27)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

ITSN2_HUMAN
θ value	3.19293e-05 (rank : 24)	NC score	0.178835 (rank : 95)
Query Neighborhood Hits	196	Target Neighborhood Hits	1173	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SYT10_HUMAN
θ value	4.1701e-05 (rank : 25)	NC score	0.378770 (rank : 19)
Query Neighborhood Hits	196	Target Neighborhood Hits	134	Shared Neighborhood Hits	99
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT10_MOUSE
θ value	4.1701e-05 (rank : 26)	NC score	0.382561 (rank : 15)
Query Neighborhood Hits	196	Target Neighborhood Hits	133	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_HUMAN
θ value	4.1701e-05 (rank : 27)	NC score	0.375531 (rank : 21)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	99
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
θ value	4.1701e-05 (rank : 28)	NC score	0.374848 (rank : 23)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

KPCA_MOUSE
θ value	5.44631e-05 (rank : 29)	NC score	0.122840 (rank : 117)
Query Neighborhood Hits	196	Target Neighborhood Hits	1067	Shared Neighborhood Hits	105
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

FA62A_HUMAN
θ value	7.1131e-05 (rank : 30)	NC score	0.392222 (rank : 9)
Query Neighborhood Hits	196	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT3_HUMAN
θ value	0.000121331 (rank : 31)	NC score	0.382770 (rank : 13)
Query Neighborhood Hits	196	Target Neighborhood Hits	145	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2A_MOUSE
θ value	0.000158464 (rank : 32)	NC score	0.386894 (rank : 11)
Query Neighborhood Hits	196	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

SYT3_MOUSE
θ value	0.000158464 (rank : 33)	NC score	0.382746 (rank : 14)
Query Neighborhood Hits	196	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_HUMAN
θ value	0.000158464 (rank : 34)	NC score	0.371681 (rank : 28)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
θ value	0.000158464 (rank : 35)	NC score	0.371559 (rank : 29)
Query Neighborhood Hits	196	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

PA24D_MOUSE
θ value	0.00020696 (rank : 36)	NC score	0.280154 (rank : 52)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

FA62A_MOUSE
θ value	0.000270298 (rank : 37)	NC score	0.391752 (rank : 10)
Query Neighborhood Hits	196	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

DOC2A_HUMAN
θ value	0.00035302 (rank : 38)	NC score	0.384068 (rank : 12)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	100
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT7_HUMAN
θ value	0.00035302 (rank : 39)	NC score	0.371459 (rank : 30)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	98
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

UN13D_HUMAN
θ value	0.00035302 (rank : 40)	NC score	0.358568 (rank : 34)
Query Neighborhood Hits	196	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

BAIP3_MOUSE
θ value	0.000602161 (rank : 41)	NC score	0.350796 (rank : 35)
Query Neighborhood Hits	196	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RP3A_HUMAN
θ value	0.000602161 (rank : 42)	NC score	0.375112 (rank : 22)
Query Neighborhood Hits	196	Target Neighborhood Hits	305	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_MOUSE
θ value	0.000786445 (rank : 43)	NC score	0.373007 (rank : 24)
Query Neighborhood Hits	196	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RFIP2_HUMAN
θ value	0.00102713 (rank : 44)	NC score	0.304292 (rank : 42)
Query Neighborhood Hits	196	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

BAIP3_HUMAN
θ value	0.00134147 (rank : 45)	NC score	0.346230 (rank : 36)
Query Neighborhood Hits	196	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

DOC2B_MOUSE
θ value	0.00175202 (rank : 46)	NC score	0.380181 (rank : 16)
Query Neighborhood Hits	196	Target Neighborhood Hits	169	Shared Neighborhood Hits	101
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

UN13A_HUMAN
θ value	0.00175202 (rank : 47)	NC score	0.291458 (rank : 47)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

DOC2G_MOUSE
θ value	0.00298849 (rank : 48)	NC score	0.360714 (rank : 33)
Query Neighborhood Hits	196	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

PA24D_HUMAN
θ value	0.00298849 (rank : 49)	NC score	0.233949 (rank : 64)
Query Neighborhood Hits	196	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYTL2_MOUSE
θ value	0.00298849 (rank : 50)	NC score	0.304718 (rank : 41)
Query Neighborhood Hits	196	Target Neighborhood Hits	253	Shared Neighborhood Hits	87
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CPNE3_MOUSE
θ value	0.00390308 (rank : 51)	NC score	0.237959 (rank : 62)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

DOC2B_HUMAN
θ value	0.00390308 (rank : 52)	NC score	0.379397 (rank : 17)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	101
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

UN13B_MOUSE
θ value	0.00390308 (rank : 53)	NC score	0.286255 (rank : 49)
Query Neighborhood Hits	196	Target Neighborhood Hits	210	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CPNE8_HUMAN
θ value	0.0113563 (rank : 54)	NC score	0.232453 (rank : 67)
Query Neighborhood Hits	196	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	0.0113563 (rank : 55)	NC score	0.229605 (rank : 69)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN1_HUMAN
θ value	0.0148317 (rank : 56)	NC score	0.124521 (rank : 115)
Query Neighborhood Hits	196	Target Neighborhood Hits	1757	Shared Neighborhood Hits	123
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	0.0148317 (rank : 57)	NC score	0.125630 (rank : 112)
Query Neighborhood Hits	196	Target Neighborhood Hits	1669	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SYTL2_HUMAN
θ value	0.0148317 (rank : 58)	NC score	0.301763 (rank : 45)
Query Neighborhood Hits	196	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CPNE5_HUMAN
θ value	0.0193708 (rank : 59)	NC score	0.229088 (rank : 71)
Query Neighborhood Hits	196	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	0.0193708 (rank : 60)	NC score	0.229248 (rank : 70)
Query Neighborhood Hits	196	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE7_HUMAN
θ value	0.0193708 (rank : 61)	NC score	0.212741 (rank : 74)
Query Neighborhood Hits	196	Target Neighborhood Hits	92	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

NEDD4_HUMAN
θ value	0.0193708 (rank : 62)	NC score	0.197442 (rank : 81)
Query Neighborhood Hits	196	Target Neighborhood Hits	214	Shared Neighborhood Hits	97
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PERF_MOUSE
θ value	0.0193708 (rank : 63)	NC score	0.157700 (rank : 104)
Query Neighborhood Hits	196	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

SYTL5_MOUSE
θ value	0.0193708 (rank : 64)	NC score	0.289657 (rank : 48)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

ATRX_MOUSE
θ value	0.0252991 (rank : 65)	NC score	0.035628 (rank : 152)
Query Neighborhood Hits	196	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

RASA2_MOUSE
θ value	0.0330416 (rank : 66)	NC score	0.225357 (rank : 72)
Query Neighborhood Hits	196	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PA24F_HUMAN
θ value	0.0431538 (rank : 67)	NC score	0.159806 (rank : 103)
Query Neighborhood Hits	196	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PERF_HUMAN
θ value	0.0431538 (rank : 68)	NC score	0.142653 (rank : 107)
Query Neighborhood Hits	196	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

CPNE3_HUMAN
θ value	0.0563607 (rank : 69)	NC score	0.232462 (rank : 66)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	81
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.178030 (rank : 96)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	0.0736092 (rank : 71)	NC score	0.177451 (rank : 98)
Query Neighborhood Hits	196	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE6_HUMAN
θ value	0.0736092 (rank : 72)	NC score	0.196970 (rank : 83)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.194328 (rank : 86)
Query Neighborhood Hits	196	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

K0528_HUMAN
θ value	0.0736092 (rank : 74)	NC score	0.303423 (rank : 43)
Query Neighborhood Hits	196	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.0736092 (rank : 75)	NC score	0.303074 (rank : 44)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

LUZP1_MOUSE
θ value	0.0736092 (rank : 76)	NC score	0.036035 (rank : 151)
Query Neighborhood Hits	196	Target Neighborhood Hits	940	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

NEDD4_MOUSE
θ value	0.0736092 (rank : 77)	NC score	0.195083 (rank : 84)
Query Neighborhood Hits	196	Target Neighborhood Hits	212	Shared Neighborhood Hits	98
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PA24B_MOUSE
θ value	0.0961366 (rank : 78)	NC score	0.232616 (rank : 65)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

NIPBL_HUMAN
θ value	0.125558 (rank : 79)	NC score	0.038789 (rank : 149)
Query Neighborhood Hits	196	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SNCAP_HUMAN
θ value	0.163984 (rank : 80)	NC score	0.028171 (rank : 159)
Query Neighborhood Hits	196	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

MDN1_HUMAN
θ value	0.21417 (rank : 81)	NC score	0.049831 (rank : 140)
Query Neighborhood Hits	196	Target Neighborhood Hits	662	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PA24A_HUMAN
θ value	0.21417 (rank : 82)	NC score	0.192139 (rank : 87)
Query Neighborhood Hits	196	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	0.21417 (rank : 83)	NC score	0.197316 (rank : 82)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RASA1_HUMAN
θ value	0.21417 (rank : 84)	NC score	0.084125 (rank : 130)
Query Neighborhood Hits	196	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CTRO_MOUSE
θ value	0.279714 (rank : 85)	NC score	0.025608 (rank : 165)
Query Neighborhood Hits	196	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PA24E_HUMAN
θ value	0.279714 (rank : 86)	NC score	0.183477 (rank : 93)
Query Neighborhood Hits	196	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RASA2_HUMAN
θ value	0.279714 (rank : 87)	NC score	0.208634 (rank : 77)
Query Neighborhood Hits	196	Target Neighborhood Hits	157	Shared Neighborhood Hits	69
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SYTL5_HUMAN
θ value	0.279714 (rank : 88)	NC score	0.282964 (rank : 51)
Query Neighborhood Hits	196	Target Neighborhood Hits	237	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SMUF2_HUMAN
θ value	0.365318 (rank : 89)	NC score	0.103014 (rank : 125)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SYT11_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.309718 (rank : 38)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	0.365318 (rank : 91)	NC score	0.311330 (rank : 37)
Query Neighborhood Hits	196	Target Neighborhood Hits	116	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

TXLNB_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.027043 (rank : 163)
Query Neighborhood Hits	196	Target Neighborhood Hits	912	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

ACINU_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.040149 (rank : 147)
Query Neighborhood Hits	196	Target Neighborhood Hits	828	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANR11_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.018761 (rank : 187)
Query Neighborhood Hits	196	Target Neighborhood Hits	1289	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

SMUF1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.101481 (rank : 126)
Query Neighborhood Hits	196	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.100572 (rank : 128)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

UN13B_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.262922 (rank : 54)
Query Neighborhood Hits	196	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CCD93_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.024558 (rank : 167)
Query Neighborhood Hits	196	Target Neighborhood Hits	600	Shared Neighborhood Hits	25
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

LACTB_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.042289 (rank : 144)
Query Neighborhood Hits	196	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EP89	Gene names	Lactb, Lact1
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

MYRIP_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.044236 (rank : 142)
Query Neighborhood Hits	196	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

USE1_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.040959 (rank : 146)
Query Neighborhood Hits	196	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ43, Q8NCK1, Q9BRT4	Gene names	USE1L
Domain Architecture	No domain graphic available
Description	Vesicle transport protein USE1 (USE1-like protein) (Putative MAPK- activating protein PM26) (Protein p31).

CI039_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.025519 (rank : 166)
Query Neighborhood Hits	196	Target Neighborhood Hits	1171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

GRHL2_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.013977 (rank : 202)
Query Neighborhood Hits	196	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

RABE1_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.022443 (rank : 173)
Query Neighborhood Hits	196	Target Neighborhood Hits	1104	Shared Neighborhood Hits	44
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SYT4_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.309666 (rank : 39)
Query Neighborhood Hits	196	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

USE1_MOUSE
θ value	1.38821 (rank : 106)	NC score	0.039426 (rank : 148)
Query Neighborhood Hits	196	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ56, Q3TUK0, Q80V73, Q99MB6	Gene names	Use1l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein USE1 (USE1-like protein) (Protein D12).

ZN645_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.029120 (rank : 158)
Query Neighborhood Hits	196	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

ANGL4_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.013503 (rank : 204)
Query Neighborhood Hits	196	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

ARP2_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.016591 (rank : 196)
Query Neighborhood Hits	196	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P61160, O15142, Q96C82	Gene names	ACTR2, ARP2
Domain Architecture
Description	Actin-like protein 2 (Actin-related protein 2).

ARP2_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.016591 (rank : 197)
Query Neighborhood Hits	196	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P61161, O15142	Gene names	Actr2, Arp2
Domain Architecture
Description	Actin-like protein 2 (Actin-related protein 2).

CT102_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.033311 (rank : 155)
Query Neighborhood Hits	196	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDS0	Gene names	Gm691
Domain Architecture	No domain graphic available
Description	Protein C20orf102 homolog precursor.

ELOA1_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.017399 (rank : 194)
Query Neighborhood Hits	196	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MINK1_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.012606 (rank : 206)
Query Neighborhood Hits	196	Target Neighborhood Hits	1451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MY18A_HUMAN
θ value	1.81305 (rank : 114)	NC score	0.021357 (rank : 177)
Query Neighborhood Hits	196	Target Neighborhood Hits	1929	Shared Neighborhood Hits	55
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRI52_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.010270 (rank : 213)
Query Neighborhood Hits	196	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

CDC5L_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.041133 (rank : 145)
Query Neighborhood Hits	196	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

CPNE1_MOUSE
θ value	2.36792 (rank : 117)	NC score	0.201332 (rank : 79)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.208682 (rank : 76)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	72
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

MO4L1_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.020206 (rank : 184)
Query Neighborhood Hits	196	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.020197 (rank : 185)
Query Neighborhood Hits	196	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

NUMA1_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.017510 (rank : 193)
Query Neighborhood Hits	196	Target Neighborhood Hits	1523	Shared Neighborhood Hits	49
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

TCOF_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.031541 (rank : 157)
Query Neighborhood Hits	196	Target Neighborhood Hits	471	Shared Neighborhood Hits	25
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TP53B_HUMAN
θ value	2.36792 (rank : 123)	NC score	0.024095 (rank : 168)
Query Neighborhood Hits	196	Target Neighborhood Hits	413	Shared Neighborhood Hits	21
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ADIP_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.027865 (rank : 160)
Query Neighborhood Hits	196	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

CPNE2_HUMAN
θ value	3.0926 (rank : 125)	NC score	0.202395 (rank : 78)
Query Neighborhood Hits	196	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

DMRTA_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.017370 (rank : 195)
Query Neighborhood Hits	196	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

FLIP1_MOUSE
θ value	3.0926 (rank : 127)	NC score	0.020318 (rank : 183)
Query Neighborhood Hits	196	Target Neighborhood Hits	1176	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

K1196_HUMAN
θ value	3.0926 (rank : 128)	NC score	0.015474 (rank : 198)
Query Neighborhood Hits	196	Target Neighborhood Hits	618	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

LEO1_MOUSE
θ value	3.0926 (rank : 129)	NC score	0.017948 (rank : 189)
Query Neighborhood Hits	196	Target Neighborhood Hits	946	Shared Neighborhood Hits	34
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SASH1_MOUSE
θ value	3.0926 (rank : 130)	NC score	0.017705 (rank : 191)
Query Neighborhood Hits	196	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

SNUT1_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.027667 (rank : 161)
Query Neighborhood Hits	196	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

VPP4_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.009812 (rank : 215)
Query Neighborhood Hits	196	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q920R6, Q8CJ79, Q920B5	Gene names	Atp6v0a4, Atp6n1b
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

WWP2_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.036200 (rank : 150)
Query Neighborhood Hits	196	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

AKA12_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.034145 (rank : 154)
Query Neighborhood Hits	196	Target Neighborhood Hits	825	Shared Neighborhood Hits	39
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BIG1_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.008508 (rank : 221)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CCHCR_HUMAN
θ value	4.03905 (rank : 136)	NC score	0.020563 (rank : 180)
Query Neighborhood Hits	196	Target Neighborhood Hits	717	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCNL2_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.012263 (rank : 209)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

CP250_MOUSE
θ value	4.03905 (rank : 138)	NC score	0.020791 (rank : 179)
Query Neighborhood Hits	196	Target Neighborhood Hits	1583	Shared Neighborhood Hits	53
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CPNE1_HUMAN
θ value	4.03905 (rank : 139)	NC score	0.182248 (rank : 94)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	69
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

GOGB1_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.022951 (rank : 171)
Query Neighborhood Hits	196	Target Neighborhood Hits	2297	Shared Neighborhood Hits	61
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HSP74_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.006285 (rank : 224)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

ITCH_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.049575 (rank : 141)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

K0841_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.023782 (rank : 170)
Query Neighborhood Hits	196	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

NED4L_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.197660 (rank : 80)
Query Neighborhood Hits	196	Target Neighborhood Hits	238	Shared Neighborhood Hits	100
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	4.03905 (rank : 145)	NC score	0.194994 (rank : 85)
Query Neighborhood Hits	196	Target Neighborhood Hits	231	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

P3C2B_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.151831 (rank : 105)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PA24B_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.164438 (rank : 102)
Query Neighborhood Hits	196	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PAF49_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.022306 (rank : 174)
Query Neighborhood Hits	196	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

SAFB2_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.022133 (rank : 175)
Query Neighborhood Hits	196	Target Neighborhood Hits	581	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SYT8_MOUSE
θ value	4.03905 (rank : 150)	NC score	0.260188 (rank : 56)
Query Neighborhood Hits	196	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

WWP1_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.052683 (rank : 139)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ALO17_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.022030 (rank : 176)
Query Neighborhood Hits	196	Target Neighborhood Hits	317	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CDC5L_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.035323 (rank : 153)
Query Neighborhood Hits	196	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

CDT1_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.027487 (rank : 162)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

CING_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.017577 (rank : 192)
Query Neighborhood Hits	196	Target Neighborhood Hits	1432	Shared Neighborhood Hits	48
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CJ068_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.032271 (rank : 156)
Query Neighborhood Hits	196	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

DLX2_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.003646 (rank : 229)
Query Neighborhood Hits	196	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P40764	Gene names	Dlx2, Tes-1, Tes1
Domain Architecture
Description	Homeobox protein DLX-2 (Homeobox protein TES-1).

MY18A_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.017999 (rank : 188)
Query Neighborhood Hits	196	Target Neighborhood Hits	1989	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH9_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.012057 (rank : 210)
Query Neighborhood Hits	196	Target Neighborhood Hits	1762	Shared Neighborhood Hits	49
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	5.27518 (rank : 160)	NC score	0.012496 (rank : 207)
Query Neighborhood Hits	196	Target Neighborhood Hits	1829	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYRIP_HUMAN
θ value	5.27518 (rank : 161)	NC score	0.042323 (rank : 143)
Query Neighborhood Hits	196	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NP1L4_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.015339 (rank : 199)
Query Neighborhood Hits	196	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

PA24E_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.174237 (rank : 99)
Query Neighborhood Hits	196	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PIR_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.026139 (rank : 164)
Query Neighborhood Hits	196	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O00625, Q5U0G0	Gene names	PIR
Domain Architecture
Description	Pirin.

ATBF1_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.002414 (rank : 230)
Query Neighborhood Hits	196	Target Neighborhood Hits	1841	Shared Neighborhood Hits	36
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BAZ1B_MOUSE
θ value	6.88961 (rank : 166)	NC score	0.011280 (rank : 211)
Query Neighborhood Hits	196	Target Neighborhood Hits	394	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CHD9_MOUSE
θ value	6.88961 (rank : 167)	NC score	0.008567 (rank : 220)
Query Neighborhood Hits	196	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ERC2_MOUSE
θ value	6.88961 (rank : 168)	NC score	0.017929 (rank : 190)
Query Neighborhood Hits	196	Target Neighborhood Hits	1166	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

EYA1_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.009235 (rank : 218)
Query Neighborhood Hits	196	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

FKBP9_MOUSE
θ value	6.88961 (rank : 170)	NC score	0.005987 (rank : 227)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z247, Q80ZZ6, Q8R386, Q9CVM0, Q9JHX5	Gene names	Fkbp9, Fkbp60, Fkbp63
Domain Architecture
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP65RS).

MINK1_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.012443 (rank : 208)
Query Neighborhood Hits	196	Target Neighborhood Hits	1477	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYST4_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.007523 (rank : 222)
Query Neighborhood Hits	196	Target Neighborhood Hits	416	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RBBP5_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.006907 (rank : 223)
Query Neighborhood Hits	196	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

SMC3_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.020371 (rank : 182)
Query Neighborhood Hits	196	Target Neighborhood Hits	1186	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.020395 (rank : 181)
Query Neighborhood Hits	196	Target Neighborhood Hits	1187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

TDRD1_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.014090 (rank : 201)
Query Neighborhood Hits	196	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

TRPM7_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.006141 (rank : 225)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

WASIP_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.013744 (rank : 203)
Query Neighborhood Hits	196	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ADIP_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.022947 (rank : 172)
Query Neighborhood Hits	196	Target Neighborhood Hits	470	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

APXL_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.009664 (rank : 216)
Query Neighborhood Hits	196	Target Neighborhood Hits	553	Shared Neighborhood Hits	18
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

CE005_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.010222 (rank : 214)
Query Neighborhood Hits	196	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CJ078_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.019311 (rank : 186)
Query Neighborhood Hits	196	Target Neighborhood Hits	559	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CT2NL_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.023973 (rank : 169)
Query Neighborhood Hits	196	Target Neighborhood Hits	1059	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DIDO1_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.010667 (rank : 212)
Query Neighborhood Hits	196	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GOGA2_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.012613 (rank : 205)
Query Neighborhood Hits	196	Target Neighborhood Hits	856	Shared Neighborhood Hits	32
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

RGS12_HUMAN
θ value	8.99809 (rank : 186)	NC score	0.004488 (rank : 228)
Query Neighborhood Hits	196	Target Neighborhood Hits	333	Shared Neighborhood Hits	9
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

RLF_HUMAN
θ value	8.99809 (rank : 187)	NC score	-0.001257 (rank : 231)
Query Neighborhood Hits	196	Target Neighborhood Hits	775	Shared Neighborhood Hits	6
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

SF04_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.009158 (rank : 219)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

SYGP1_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.056040 (rank : 136)
Query Neighborhood Hits	196	Target Neighborhood Hits	589	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SYT12_HUMAN
θ value	8.99809 (rank : 190)	NC score	0.253311 (rank : 59)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.260622 (rank : 55)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT4_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.307806 (rank : 40)
Query Neighborhood Hits	196	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

TEX14_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.009611 (rank : 217)
Query Neighborhood Hits	196	Target Neighborhood Hits	1333	Shared Neighborhood Hits	37
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRI66_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.014384 (rank : 200)
Query Neighborhood Hits	196	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	8.99809 (rank : 195)	NC score	0.020943 (rank : 178)
Query Neighborhood Hits	196	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZN198_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.006016 (rank : 226)
Query Neighborhood Hits	196	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

DAB2P_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.056447 (rank : 135)
Query Neighborhood Hits	196	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.054604 (rank : 137)
Query Neighborhood Hits	196	Target Neighborhood Hits	284	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

NGAP_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.052897 (rank : 138)
Query Neighborhood Hits	196	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

P3C2A_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.116465 (rank : 118)
Query Neighborhood Hits	196	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.115365 (rank : 119)
Query Neighborhood Hits	196	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PA24C_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.060769 (rank : 133)
Query Neighborhood Hits	196	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

PA24F_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.143816 (rank : 106)
Query Neighborhood Hits	196	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PLCD1_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.091664 (rank : 129)
Query Neighborhood Hits	196	Target Neighborhood Hits	93	Shared Neighborhood Hits	54
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.069049 (rank : 132)
Query Neighborhood Hits	196	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA3_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.191573 (rank : 88)
Query Neighborhood Hits	196	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.172127 (rank : 100)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.115142 (rank : 120)
Query Neighborhood Hits	196	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.109802 (rank : 121)
Query Neighborhood Hits	196	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RGS3_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.077017 (rank : 131)
Query Neighborhood Hits	196	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RIMS1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.177759 (rank : 97)
Query Neighborhood Hits	196	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.190760 (rank : 89)
Query Neighborhood Hits	196	Target Neighborhood Hits	342	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.189053 (rank : 91)
Query Neighborhood Hits	196	Target Neighborhood Hits	376	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS3_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.104411 (rank : 123)
Query Neighborhood Hits	196	Target Neighborhood Hits	66	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.101128 (rank : 127)
Query Neighborhood Hits	196	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.135383 (rank : 109)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.136732 (rank : 108)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYT13_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.221353 (rank : 73)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.212455 (rank : 75)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.187922 (rank : 92)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.190436 (rank : 90)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT15_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.244113 (rank : 61)
Query Neighborhood Hits	196	Target Neighborhood Hits	112	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT15_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.234906 (rank : 63)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYTL1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.267882 (rank : 53)
Query Neighborhood Hits	196	Target Neighborhood Hits	227	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.247401 (rank : 60)
Query Neighborhood Hits	196	Target Neighborhood Hits	314	Shared Neighborhood Hits	75
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL3_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.230280 (rank : 68)
Query Neighborhood Hits	196	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL4_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.257499 (rank : 58)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.258840 (rank : 57)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

TAC2N_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.106322 (rank : 122)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.103591 (rank : 124)
Query Neighborhood Hits	196	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

WWC1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.057066 (rank : 134)
Query Neighborhood Hits	196	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

Hits sorted by NC score

OTOF_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	196	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_HUMAN
NC score	0.993605 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	196	Target Neighborhood Hits	168	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MYOF_HUMAN
NC score	0.918418 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	196	Target Neighborhood Hits	147	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

DYSF_HUMAN
NC score	0.914405 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	196	Target Neighborhood Hits	170	Shared Neighborhood Hits	102
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
NC score	0.910911 (rank : 5)	θ value	0 (rank : 2)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RASL1_HUMAN
NC score	0.438515 (rank : 6)	θ value	2.28291e-11 (rank : 6)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	98
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
NC score	0.424086 (rank : 7)	θ value	3.29651e-10 (rank : 7)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL2_HUMAN
NC score	0.410349 (rank : 8)	θ value	5.81887e-07 (rank : 9)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	100
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

FA62A_HUMAN
NC score	0.392222 (rank : 9)	θ value	7.1131e-05 (rank : 30)
Query Neighborhood Hits	196	Target Neighborhood Hits	168	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
NC score	0.391752 (rank : 10)	θ value	0.000270298 (rank : 37)
Query Neighborhood Hits	196	Target Neighborhood Hits	155	Shared Neighborhood Hits	102
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

DOC2A_MOUSE
NC score	0.386894 (rank : 11)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	196	Target Neighborhood Hits	140	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.384068 (rank : 12)	θ value	0.00035302 (rank : 38)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	100
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT3_HUMAN
NC score	0.382770 (rank : 13)	θ value	0.000121331 (rank : 31)
Query Neighborhood Hits	196	Target Neighborhood Hits	145	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
NC score	0.382746 (rank : 14)	θ value	0.000158464 (rank : 33)
Query Neighborhood Hits	196	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT10_MOUSE
NC score	0.382561 (rank : 15)	θ value	4.1701e-05 (rank : 26)
Query Neighborhood Hits	196	Target Neighborhood Hits	133	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

DOC2B_MOUSE
NC score	0.380181 (rank : 16)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	196	Target Neighborhood Hits	169	Shared Neighborhood Hits	101
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_HUMAN
NC score	0.379397 (rank : 17)	θ value	0.00390308 (rank : 52)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	101
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT5_MOUSE
NC score	0.379042 (rank : 18)	θ value	1.09739e-05 (rank : 13)
Query Neighborhood Hits	196	Target Neighborhood Hits	140	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT10_HUMAN
NC score	0.378770 (rank : 19)	θ value	4.1701e-05 (rank : 25)
Query Neighborhood Hits	196	Target Neighborhood Hits	134	Shared Neighborhood Hits	99
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT5_HUMAN
NC score	0.376209 (rank : 20)	θ value	2.44474e-05 (rank : 22)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT9_HUMAN
NC score	0.375531 (rank : 21)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	99
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

RP3A_HUMAN
NC score	0.375112 (rank : 22)	θ value	0.000602161 (rank : 42)
Query Neighborhood Hits	196	Target Neighborhood Hits	305	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT9_MOUSE
NC score	0.374848 (rank : 23)	θ value	4.1701e-05 (rank : 28)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

RP3A_MOUSE
NC score	0.373007 (rank : 24)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	196	Target Neighborhood Hits	510	Shared Neighborhood Hits	105
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT1_HUMAN
NC score	0.372917 (rank : 25)	θ value	2.44474e-05 (rank : 18)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.372907 (rank : 26)	θ value	2.44474e-05 (rank : 19)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	98
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT7_MOUSE
NC score	0.372565 (rank : 27)	θ value	2.44474e-05 (rank : 23)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	100
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT6_HUMAN
NC score	0.371681 (rank : 28)	θ value	0.000158464 (rank : 34)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	99
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
NC score	0.371559 (rank : 29)	θ value	0.000158464 (rank : 35)
Query Neighborhood Hits	196	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_HUMAN
NC score	0.371459 (rank : 30)	θ value	0.00035302 (rank : 39)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	98
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT2_MOUSE
NC score	0.370171 (rank : 31)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	196	Target Neighborhood Hits	143	Shared Neighborhood Hits	99
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.369253 (rank : 32)	θ value	2.44474e-05 (rank : 20)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	99
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

DOC2G_MOUSE
NC score	0.360714 (rank : 33)	θ value	0.00298849 (rank : 48)
Query Neighborhood Hits	196	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

UN13D_HUMAN
NC score	0.358568 (rank : 34)	θ value	0.00035302 (rank : 40)
Query Neighborhood Hits	196	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

BAIP3_MOUSE
NC score	0.350796 (rank : 35)	θ value	0.000602161 (rank : 41)
Query Neighborhood Hits	196	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_HUMAN
NC score	0.346230 (rank : 36)	θ value	0.00134147 (rank : 45)
Query Neighborhood Hits	196	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYT11_MOUSE
NC score	0.311330 (rank : 37)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	196	Target Neighborhood Hits	116	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.309718 (rank : 38)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT4_MOUSE
NC score	0.309666 (rank : 39)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	196	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_HUMAN
NC score	0.307806 (rank : 40)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	196	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYTL2_MOUSE
NC score	0.304718 (rank : 41)	θ value	0.00298849 (rank : 50)
Query Neighborhood Hits	196	Target Neighborhood Hits	253	Shared Neighborhood Hits	87
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

RFIP2_HUMAN
NC score	0.304292 (rank : 42)	θ value	0.00102713 (rank : 44)
Query Neighborhood Hits	196	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

K0528_HUMAN
NC score	0.303423 (rank : 43)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	196	Target Neighborhood Hits	96	Shared Neighborhood Hits	69
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.303074 (rank : 44)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

SYTL2_HUMAN
NC score	0.301763 (rank : 45)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	196	Target Neighborhood Hits	248	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

PCLO_HUMAN
NC score	0.299179 (rank : 46)	θ value	3.77169e-06 (rank : 10)
Query Neighborhood Hits	196	Target Neighborhood Hits	2046	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

UN13A_HUMAN
NC score	0.291458 (rank : 47)	θ value	0.00175202 (rank : 47)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

SYTL5_MOUSE
NC score	0.289657 (rank : 48)	θ value	0.0193708 (rank : 64)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

UN13B_MOUSE
NC score	0.286255 (rank : 49)	θ value	0.00390308 (rank : 53)
Query Neighborhood Hits	196	Target Neighborhood Hits	210	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PCLO_MOUSE
NC score	0.284734 (rank : 50)	θ value	4.0297e-08 (rank : 8)
Query Neighborhood Hits	196	Target Neighborhood Hits	2275	Shared Neighborhood Hits	149
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYTL5_HUMAN
NC score	0.282964 (rank : 51)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	196	Target Neighborhood Hits	237	Shared Neighborhood Hits	96
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

PA24D_MOUSE
NC score	0.280154 (rank : 52)	θ value	0.00020696 (rank : 36)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	84
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYTL1_HUMAN
NC score	0.267882 (rank : 53)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	196	Target Neighborhood Hits	227	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

UN13B_HUMAN
NC score	0.262922 (rank : 54)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	196	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT12_MOUSE
NC score	0.260622 (rank : 55)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT8_MOUSE
NC score	0.260188 (rank : 56)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	196	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL4_MOUSE
NC score	0.258840 (rank : 57)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	196	Target Neighborhood Hits	137	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
NC score	0.257499 (rank : 58)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYT12_HUMAN
NC score	0.253311 (rank : 59)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	66
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYTL1_MOUSE
NC score	0.247401 (rank : 60)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	196	Target Neighborhood Hits	314	Shared Neighborhood Hits	75
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYT15_HUMAN
NC score	0.244113 (rank : 61)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	196	Target Neighborhood Hits	112	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

CPNE3_MOUSE
NC score	0.237959 (rank : 62)	θ value	0.00390308 (rank : 51)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

SYT15_MOUSE
NC score	0.234906 (rank : 63)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

PA24D_HUMAN
NC score	0.233949 (rank : 64)	θ value	0.00298849 (rank : 49)
Query Neighborhood Hits	196	Target Neighborhood Hits	97	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24B_MOUSE
NC score	0.232616 (rank : 65)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	196	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

CPNE3_HUMAN
NC score	0.232462 (rank : 66)	θ value	0.0563607 (rank : 69)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	81
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE8_HUMAN
NC score	0.232453 (rank : 67)	θ value	0.0113563 (rank : 54)
Query Neighborhood Hits	196	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

SYTL3_MOUSE
NC score	0.230280 (rank : 68)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	196	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

CPNE8_MOUSE
NC score	0.229605 (rank : 69)	θ value	0.0113563 (rank : 55)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	77
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE5_MOUSE
NC score	0.229248 (rank : 70)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	196	Target Neighborhood Hits	86	Shared Neighborhood Hits	77
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.229088 (rank : 71)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	196	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

RASA2_MOUSE
NC score	0.225357 (rank : 72)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	196	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

SYT13_HUMAN
NC score	0.221353 (rank : 73)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

CPNE7_HUMAN
NC score	0.212741 (rank : 74)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	196	Target Neighborhood Hits	92	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SYT13_MOUSE
NC score	0.212455 (rank : 75)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

CPNE2_MOUSE
NC score	0.208682 (rank : 76)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	72
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

RASA2_HUMAN
NC score	0.208634 (rank : 77)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	196	Target Neighborhood Hits	157	Shared Neighborhood Hits	69
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

CPNE2_HUMAN
NC score	0.202395 (rank : 78)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	196	Target Neighborhood Hits	75	Shared Neighborhood Hits	69
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE1_MOUSE
NC score	0.201332 (rank : 79)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

NED4L_HUMAN
NC score	0.197660 (rank : 80)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	196	Target Neighborhood Hits	238	Shared Neighborhood Hits	100
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_HUMAN
NC score	0.197442 (rank : 81)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	196	Target Neighborhood Hits	214	Shared Neighborhood Hits	97
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PA24A_MOUSE
NC score	0.197316 (rank : 82)	θ value	0.21417 (rank : 83)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE6_HUMAN
NC score	0.196970 (rank : 83)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

NEDD4_MOUSE
NC score	0.195083 (rank : 84)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	196	Target Neighborhood Hits	212	Shared Neighborhood Hits	98
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NED4L_MOUSE
NC score	0.194994 (rank : 85)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	196	Target Neighborhood Hits	231	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

CPNE6_MOUSE
NC score	0.194328 (rank : 86)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	196	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

PA24A_HUMAN
NC score	0.192139 (rank : 87)	θ value	0.21417 (rank : 82)
Query Neighborhood Hits	196	Target Neighborhood Hits	88	Shared Neighborhood Hits	70
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RASA3_HUMAN
NC score	0.191573 (rank : 88)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	196	Target Neighborhood Hits	166	Shared Neighborhood Hits	68
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RIMS2_HUMAN
NC score	0.190760 (rank : 89)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	196	Target Neighborhood Hits	342	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SYT14_MOUSE
NC score	0.190436 (rank : 90)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS2_MOUSE
NC score	0.189053 (rank : 91)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	196	Target Neighborhood Hits	376	Shared Neighborhood Hits	94
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SYT14_HUMAN
NC score	0.187922 (rank : 92)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

PA24E_HUMAN
NC score	0.183477 (rank : 93)	θ value	0.279714 (rank : 86)
Query Neighborhood Hits	196	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

CPNE1_HUMAN
NC score	0.182248 (rank : 94)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	69
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

ITSN2_HUMAN
NC score	0.178835 (rank : 95)	θ value	3.19293e-05 (rank : 24)
Query Neighborhood Hits	196	Target Neighborhood Hits	1173	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CPNE4_HUMAN
NC score	0.178030 (rank : 96)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	63
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

RIMS1_HUMAN
NC score	0.177759 (rank : 97)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	196	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

CPNE4_MOUSE
NC score	0.177451 (rank : 98)	θ value	0.0736092 (rank : 71)
Query Neighborhood Hits	196	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

PA24E_MOUSE
NC score	0.174237 (rank : 99)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	196	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RASA3_MOUSE
NC score	0.172127 (rank : 100)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	196	Target Neighborhood Hits	144	Shared Neighborhood Hits	65
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

ITSN2_MOUSE
NC score	0.170073 (rank : 101)	θ value	1.43324e-05 (rank : 14)
Query Neighborhood Hits	196	Target Neighborhood Hits	1371	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

PA24B_HUMAN
NC score	0.164438 (rank : 102)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	196	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24F_HUMAN
NC score	0.159806 (rank : 103)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	196	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PERF_MOUSE
NC score	0.157700 (rank : 104)	θ value	0.0193708 (rank : 63)
Query Neighborhood Hits	196	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

P3C2B_HUMAN
NC score	0.151831 (rank : 105)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PA24F_MOUSE
NC score	0.143816 (rank : 106)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	196	Target Neighborhood Hits	93	Shared Neighborhood Hits	68
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PERF_HUMAN
NC score	0.142653 (rank : 107)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	196	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

RIMS4_MOUSE
NC score	0.136732 (rank : 108)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.135383 (rank : 109)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

KPCG_MOUSE
NC score	0.131066 (rank : 110)	θ value	1.87187e-05 (rank : 15)
Query Neighborhood Hits	196	Target Neighborhood Hits	1123	Shared Neighborhood Hits	102
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.130894 (rank : 111)	θ value	2.44474e-05 (rank : 17)
Query Neighborhood Hits	196	Target Neighborhood Hits	1126	Shared Neighborhood Hits	102
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

ITSN1_MOUSE
NC score	0.125630 (rank : 112)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	196	Target Neighborhood Hits	1669	Shared Neighborhood Hits	125
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KPCB_MOUSE
NC score	0.125187 (rank : 113)	θ value	4.92598e-06 (rank : 11)
Query Neighborhood Hits	196	Target Neighborhood Hits	1117	Shared Neighborhood Hits	103
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_HUMAN
NC score	0.124936 (rank : 114)	θ value	2.44474e-05 (rank : 16)
Query Neighborhood Hits	196	Target Neighborhood Hits	1070	Shared Neighborhood Hits	105
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

ITSN1_HUMAN
NC score	0.124521 (rank : 115)	θ value	0.0148317 (rank : 56)
Query Neighborhood Hits	196	Target Neighborhood Hits	1757	Shared Neighborhood Hits	123
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KPCB_HUMAN
NC score	0.123565 (rank : 116)	θ value	1.09739e-05 (rank : 12)
Query Neighborhood Hits	196	Target Neighborhood Hits	1121	Shared Neighborhood Hits	103
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.122840 (rank : 117)	θ value	5.44631e-05 (rank : 29)
Query Neighborhood Hits	196	Target Neighborhood Hits	1067	Shared Neighborhood Hits	105
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

P3C2A_HUMAN
NC score	0.116465 (rank : 118)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	196	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.115365 (rank : 119)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	196	Target Neighborhood Hits	181	Shared Neighborhood Hits	58
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RFIP1_HUMAN
NC score	0.115142 (rank : 120)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	196	Target Neighborhood Hits	236	Shared Neighborhood Hits	40
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFIP1_MOUSE
NC score	0.109802 (rank : 121)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	196	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

TAC2N_HUMAN
NC score	0.106322 (rank : 122)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

RIMS3_HUMAN
NC score	0.104411 (rank : 123)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	196	Target Neighborhood Hits	66	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

TAC2N_MOUSE
NC score	0.103591 (rank : 124)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	196	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

SMUF2_HUMAN
NC score	0.103014 (rank : 125)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_HUMAN
NC score	0.101481 (rank : 126)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	196	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

RIMS3_MOUSE
NC score	0.101128 (rank : 127)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	196	Target Neighborhood Hits	67	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SMUF1_MOUSE
NC score	0.100572 (rank : 128)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	196	Target Neighborhood Hits	142	Shared Neighborhood Hits	69
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

PLCD1_HUMAN
NC score	0.091664 (rank : 129)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	196	Target Neighborhood Hits	93	Shared Neighborhood Hits	54
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA1_HUMAN
NC score	0.084125 (rank : 130)	θ value	0.21417 (rank : 84)
Query Neighborhood Hits	196	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RGS3_HUMAN
NC score	0.077017 (rank : 131)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	196	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PLCD1_MOUSE
NC score	0.069049 (rank : 132)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	196	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PA24C_HUMAN
NC score	0.060769 (rank : 133)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	196	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UP65, O75457, Q9UG68	Gene names	PLA2G4C
Domain Architecture
Description	Cytosolic phospholipase A2 gamma precursor (EC 3.1.1.4) (cPLA2-gamma) (Phospholipase A2 group IVC).

WWC1_MOUSE
NC score	0.057066 (rank : 134)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	196	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

DAB2P_HUMAN
NC score	0.056447 (rank : 135)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	196	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

SYGP1_HUMAN
NC score	0.056040 (rank : 136)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	196	Target Neighborhood Hits	589	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

DAB2P_MOUSE
NC score	0.054604 (rank : 137)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	196	Target Neighborhood Hits	284	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

NGAP_HUMAN
NC score	0.052897 (rank : 138)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	196	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

WWP1_MOUSE
NC score	0.052683 (rank : 139)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	196	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MDN1_HUMAN
NC score	0.049831 (rank : 140)	θ value	0.21417 (rank : 81)
Query Neighborhood Hits	196	Target Neighborhood Hits	662	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

ITCH_HUMAN
NC score	0.049575 (rank : 141)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

MYRIP_MOUSE
NC score	0.044236 (rank : 142)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	196	Target Neighborhood Hits	207	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MYRIP_HUMAN
NC score	0.042323 (rank : 143)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	196	Target Neighborhood Hits	269	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

LACTB_MOUSE
NC score	0.042289 (rank : 144)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	196	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EP89	Gene names	Lactb, Lact1
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

CDC5L_MOUSE
NC score	0.041133 (rank : 145)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	196	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

USE1_HUMAN
NC score	0.040959 (rank : 146)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	196	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ43, Q8NCK1, Q9BRT4	Gene names	USE1L
Domain Architecture	No domain graphic available
Description	Vesicle transport protein USE1 (USE1-like protein) (Putative MAPK- activating protein PM26) (Protein p31).

ACINU_HUMAN
NC score	0.040149 (rank : 147)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	196	Target Neighborhood Hits	828	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

USE1_MOUSE
NC score	0.039426 (rank : 148)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	196	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQ56, Q3TUK0, Q80V73, Q99MB6	Gene names	Use1l
Domain Architecture	No domain graphic available
Description	Vesicle transport protein USE1 (USE1-like protein) (Protein D12).

NIPBL_HUMAN
NC score	0.038789 (rank : 149)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	196	Target Neighborhood Hits	1311	Shared Neighborhood Hits	48
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WWP2_MOUSE
NC score	0.036200 (rank : 150)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	196	Target Neighborhood Hits	118	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

LUZP1_MOUSE
NC score	0.036035 (rank : 151)	θ value	0.0736092 (rank : 76)
Query Neighborhood Hits	196	Target Neighborhood Hits	940	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

ATRX_MOUSE
NC score	0.035628 (rank : 152)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	196	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CDC5L_HUMAN
NC score	0.035323 (rank : 153)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	196	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

AKA12_HUMAN
NC score	0.034145 (rank : 154)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	196	Target Neighborhood Hits	825	Shared Neighborhood Hits	39
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CT102_MOUSE
NC score	0.033311 (rank : 155)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	196	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PDS0	Gene names	Gm691
Domain Architecture	No domain graphic available
Description	Protein C20orf102 homolog precursor.

CJ068_HUMAN
NC score	0.032271 (rank : 156)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	196	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

TCOF_MOUSE
NC score	0.031541 (rank : 157)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	196	Target Neighborhood Hits	471	Shared Neighborhood Hits	25
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ZN645_HUMAN
NC score	0.029120 (rank : 158)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	196	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N7E2, Q6DJY9	Gene names	ZNF645
Domain Architecture	No domain graphic available
Description	Zinc finger protein 645.

SNCAP_HUMAN
NC score	0.028171 (rank : 159)	θ value	0.163984 (rank : 80)
Query Neighborhood Hits	196	Target Neighborhood Hits	313	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ADIP_MOUSE
NC score	0.027865 (rank : 160)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	196	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

SNUT1_HUMAN
NC score	0.027667 (rank : 161)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	196	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	O43290, Q53GB5	Gene names	SART1
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 1 (U4/U6.U5 tri-snRNP-associated 110 kDa protein) (Squamous cell carcinoma antigen recognized by T cells 1) (SART-1) (hSART-1) (hSnu66).

CDT1_MOUSE
NC score	0.027487 (rank : 162)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4E9, Q8BUQ1, Q8BX29, Q8R3V0, Q8R4E8	Gene names	Cdt1, Ris2
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein).

TXLNB_HUMAN
NC score	0.027043 (rank : 163)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	196	Target Neighborhood Hits	912	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

PIR_HUMAN
NC score	0.026139 (rank : 164)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	196	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O00625, Q5U0G0	Gene names	PIR
Domain Architecture
Description	Pirin.

CTRO_MOUSE
NC score	0.025608 (rank : 165)	θ value	0.279714 (rank : 85)
Query Neighborhood Hits	196	Target Neighborhood Hits	2344	Shared Neighborhood Hits	64
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CI039_HUMAN
NC score	0.025519 (rank : 166)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	196	Target Neighborhood Hits	1171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CCD93_HUMAN
NC score	0.024558 (rank : 167)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	196	Target Neighborhood Hits	600	Shared Neighborhood Hits	25
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

TP53B_HUMAN
NC score	0.024095 (rank : 168)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	196	Target Neighborhood Hits	413	Shared Neighborhood Hits	21
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CT2NL_HUMAN
NC score	0.023973 (rank : 169)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	196	Target Neighborhood Hits	1059	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

K0841_HUMAN
NC score	0.023782 (rank : 170)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	196	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	O94927, Q6P2P7, Q7L3D5, Q96CT8	Gene names	KIAA0841
Domain Architecture	No domain graphic available
Description	Protein KIAA0841.

GOGB1_HUMAN
NC score	0.022951 (rank : 171)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	196	Target Neighborhood Hits	2297	Shared Neighborhood Hits	61
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ADIP_HUMAN
NC score	0.022947 (rank : 172)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	196	Target Neighborhood Hits	470	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

RABE1_HUMAN
NC score	0.022443 (rank : 173)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	196	Target Neighborhood Hits	1104	Shared Neighborhood Hits	44
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

PAF49_HUMAN
NC score	0.022306 (rank : 174)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	196	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

SAFB2_MOUSE
NC score	0.022133 (rank : 175)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	196	Target Neighborhood Hits	581	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

ALO17_HUMAN
NC score	0.022030 (rank : 176)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	196	Target Neighborhood Hits	317	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

MY18A_HUMAN
NC score	0.021357 (rank : 177)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	196	Target Neighborhood Hits	1929	Shared Neighborhood Hits	55
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TXND2_MOUSE
NC score	0.020943 (rank : 178)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	196	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CP250_MOUSE
NC score	0.020791 (rank : 179)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	196	Target Neighborhood Hits	1583	Shared Neighborhood Hits	53
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CCHCR_HUMAN
NC score	0.020563 (rank : 180)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	196	Target Neighborhood Hits	717	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

SMC3_MOUSE
NC score	0.020395 (rank : 181)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	196	Target Neighborhood Hits	1187	Shared Neighborhood Hits	43
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.020371 (rank : 182)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	196	Target Neighborhood Hits	1186	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

FLIP1_MOUSE
NC score	0.020318 (rank : 183)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	196	Target Neighborhood Hits	1176	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MO4L1_HUMAN
NC score	0.020206 (rank : 184)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	196	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
NC score	0.020197 (rank : 185)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	196	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

CJ078_MOUSE
NC score	0.019311 (rank : 186)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	196	Target Neighborhood Hits	559	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ANR11_HUMAN
NC score	0.018761 (rank : 187)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	196	Target Neighborhood Hits	1289	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

MY18A_MOUSE
NC score	0.017999 (rank : 188)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	196	Target Neighborhood Hits	1989	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

LEO1_MOUSE
NC score	0.017948 (rank : 189)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	196	Target Neighborhood Hits	946	Shared Neighborhood Hits	34
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ERC2_MOUSE
NC score	0.017929 (rank : 190)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	196	Target Neighborhood Hits	1166	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

SASH1_MOUSE
NC score	0.017705 (rank : 191)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	196	Target Neighborhood Hits	263	Shared Neighborhood Hits	10
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

CING_MOUSE
NC score	0.017577 (rank : 192)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	196	Target Neighborhood Hits	1432	Shared Neighborhood Hits	48
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

NUMA1_HUMAN
NC score	0.017510 (rank : 193)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	196	Target Neighborhood Hits	1523	Shared Neighborhood Hits	49
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ELOA1_HUMAN
NC score	0.017399 (rank : 194)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	196	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

DMRTA_HUMAN
NC score	0.017370 (rank : 195)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	196	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VZB9, Q8N8Y9, Q9H4B9	Gene names	DMRTA1, DMO
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor A1.

ARP2_HUMAN
NC score	0.016591 (rank : 196)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	196	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P61160, O15142, Q96C82	Gene names	ACTR2, ARP2
Domain Architecture
Description	Actin-like protein 2 (Actin-related protein 2).

ARP2_MOUSE
NC score	0.016591 (rank : 197)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	196	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P61161, O15142	Gene names	Actr2, Arp2
Domain Architecture
Description	Actin-like protein 2 (Actin-related protein 2).

K1196_HUMAN
NC score	0.015474 (rank : 198)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	196	Target Neighborhood Hits	618	Shared Neighborhood Hits	6
SwissProt Accessions	Q96KM6, Q9ULM4	Gene names	KIAA1196
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1196.

NP1L4_MOUSE
NC score	0.015339 (rank : 199)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	196	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

TRI66_MOUSE
NC score	0.014384 (rank : 200)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	196	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TDRD1_MOUSE
NC score	0.014090 (rank : 201)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	196	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

GRHL2_MOUSE
NC score	0.013977 (rank : 202)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	196	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K5C0, Q80UZ5	Gene names	Grhl2, Bom, Tcfcp2l3
Domain Architecture	No domain graphic available
Description	Grainyhead-like protein 2 homolog (Brother of mammalian grainyhead) (Transcription factor CP2-like 3).

WASIP_HUMAN
NC score	0.013744 (rank : 203)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	196	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ANGL4_HUMAN
NC score	0.013503 (rank : 204)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	196	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

GOGA2_HUMAN
NC score	0.012613 (rank : 205)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	196	Target Neighborhood Hits	856	Shared Neighborhood Hits	32
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MINK1_MOUSE
NC score	0.012606 (rank : 206)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	196	Target Neighborhood Hits	1451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH9_MOUSE
NC score	0.012496 (rank : 207)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	196	Target Neighborhood Hits	1829	Shared Neighborhood Hits	52
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MINK1_HUMAN
NC score	0.012443 (rank : 208)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	196	Target Neighborhood Hits	1477	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

CCNL2_HUMAN
NC score	0.012263 (rank : 209)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

MYH9_HUMAN
NC score	0.012057 (rank : 210)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	196	Target Neighborhood Hits	1762	Shared Neighborhood Hits	49
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

BAZ1B_MOUSE
NC score	0.011280 (rank : 211)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	196	Target Neighborhood Hits	394	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

DIDO1_HUMAN
NC score	0.010667 (rank : 212)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	196	Target Neighborhood Hits	960	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

TRI52_HUMAN
NC score	0.010270 (rank : 213)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	196	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

CE005_MOUSE
NC score	0.010222 (rank : 214)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	196	Target Neighborhood Hits	238	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

VPP4_MOUSE
NC score	0.009812 (rank : 215)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	196	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q920R6, Q8CJ79, Q920B5	Gene names	Atp6v0a4, Atp6n1b
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

APXL_HUMAN
NC score	0.009664 (rank : 216)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	196	Target Neighborhood Hits	553	Shared Neighborhood Hits	18
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

TEX14_MOUSE
NC score	0.009611 (rank : 217)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	196	Target Neighborhood Hits	1333	Shared Neighborhood Hits	37
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

EYA1_MOUSE
NC score	0.009235 (rank : 218)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	196	Target Neighborhood Hits	108	Shared Neighborhood Hits	3
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

SF04_HUMAN
NC score	0.009158 (rank : 219)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWZ8, O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3	Gene names	SF4
Domain Architecture	No domain graphic available
Description	Splicing factor 4 (RNA-binding protein RBP).

CHD9_MOUSE
NC score	0.008567 (rank : 220)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	196	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

BIG1_HUMAN
NC score	0.008508 (rank : 221)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

MYST4_MOUSE
NC score	0.007523 (rank : 222)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	196	Target Neighborhood Hits	416	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RBBP5_HUMAN
NC score	0.006907 (rank : 223)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	196	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

HSP74_HUMAN
NC score	0.006285 (rank : 224)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	13
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

TRPM7_MOUSE
NC score	0.006141 (rank : 225)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

ZN198_HUMAN
NC score	0.006016 (rank : 226)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	196	Target Neighborhood Hits	128	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

FKBP9_MOUSE
NC score	0.005987 (rank : 227)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z247, Q80ZZ6, Q8R386, Q9CVM0, Q9JHX5	Gene names	Fkbp9, Fkbp60, Fkbp63
Domain Architecture
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP65RS).

RGS12_HUMAN
NC score	0.004488 (rank : 228)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	196	Target Neighborhood Hits	333	Shared Neighborhood Hits	9
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

DLX2_MOUSE
NC score	0.003646 (rank : 229)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	196	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P40764	Gene names	Dlx2, Tes-1, Tes1
Domain Architecture
Description	Homeobox protein DLX-2 (Homeobox protein TES-1).

ATBF1_MOUSE
NC score	0.002414 (rank : 230)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	196	Target Neighborhood Hits	1841	Shared Neighborhood Hits	36
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

RLF_HUMAN
NC score	-0.001257 (rank : 231)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	196	Target Neighborhood Hits	775	Shared Neighborhood Hits	6
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).