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Network neighborhood for query Sequence : SYTL1_MOUSE

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SYTL1_MOUSE
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYTL1_HUMAN
θ value	0 (rank : 1)	NC score	0.962375 (rank : 2)
Query Neighborhood Hits	314	Target Neighborhood Hits	227	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	314	Target Neighborhood Hits	314	Shared Neighborhood Hits	314
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL2_HUMAN
θ value	3.22841e-82 (rank : 3)	NC score	0.917972 (rank : 6)
Query Neighborhood Hits	314	Target Neighborhood Hits	248	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	5.15425e-80 (rank : 4)	NC score	0.919444 (rank : 5)
Query Neighborhood Hits	314	Target Neighborhood Hits	253	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL4_MOUSE
θ value	2.24614e-67 (rank : 5)	NC score	0.920608 (rank : 4)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
θ value	1.6097e-65 (rank : 6)	NC score	0.921013 (rank : 3)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL5_HUMAN
θ value	4.38363e-63 (rank : 7)	NC score	0.908660 (rank : 8)
Query Neighborhood Hits	314	Target Neighborhood Hits	237	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_MOUSE
θ value	1.78386e-56 (rank : 8)	NC score	0.909752 (rank : 7)
Query Neighborhood Hits	314	Target Neighborhood Hits	154	Shared Neighborhood Hits	94
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
θ value	1.08726e-37 (rank : 9)	NC score	0.899465 (rank : 9)
Query Neighborhood Hits	314	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT3_HUMAN
θ value	6.40375e-22 (rank : 10)	NC score	0.788415 (rank : 10)
Query Neighborhood Hits	314	Target Neighborhood Hits	145	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
θ value	4.15078e-21 (rank : 11)	NC score	0.787594 (rank : 11)
Query Neighborhood Hits	314	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT2_MOUSE
θ value	5.42112e-21 (rank : 12)	NC score	0.787438 (rank : 13)
Query Neighborhood Hits	314	Target Neighborhood Hits	143	Shared Neighborhood Hits	93
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
θ value	7.0802e-21 (rank : 13)	NC score	0.787457 (rank : 12)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_HUMAN
θ value	2.06002e-20 (rank : 14)	NC score	0.785036 (rank : 14)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	6.62687e-19 (rank : 15)	NC score	0.783462 (rank : 15)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT6_HUMAN
θ value	1.24977e-17 (rank : 16)	NC score	0.769825 (rank : 25)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT1_HUMAN
θ value	2.13179e-17 (rank : 17)	NC score	0.778094 (rank : 18)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	2.13179e-17 (rank : 18)	NC score	0.778070 (rank : 19)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT7_MOUSE
θ value	2.7842e-17 (rank : 19)	NC score	0.781274 (rank : 16)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT6_MOUSE
θ value	8.10077e-17 (rank : 20)	NC score	0.769892 (rank : 24)
Query Neighborhood Hits	314	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT10_HUMAN
θ value	1.38178e-16 (rank : 21)	NC score	0.764882 (rank : 28)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	91
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

DOC2B_MOUSE
θ value	1.52774e-15 (rank : 22)	NC score	0.777393 (rank : 20)
Query Neighborhood Hits	314	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT9_HUMAN
θ value	1.52774e-15 (rank : 23)	NC score	0.764805 (rank : 29)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	92
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

DOC2B_HUMAN
θ value	4.44505e-15 (rank : 24)	NC score	0.776265 (rank : 23)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	92
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT11_MOUSE
θ value	7.58209e-15 (rank : 25)	NC score	0.767436 (rank : 26)
Query Neighborhood Hits	314	Target Neighborhood Hits	116	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
θ value	9.90251e-15 (rank : 26)	NC score	0.767337 (rank : 27)
Query Neighborhood Hits	314	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT10_MOUSE
θ value	1.29331e-14 (rank : 27)	NC score	0.760570 (rank : 32)
Query Neighborhood Hits	314	Target Neighborhood Hits	133	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_MOUSE
θ value	1.68911e-14 (rank : 28)	NC score	0.762203 (rank : 30)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

P3C2A_HUMAN
θ value	2.88119e-14 (rank : 29)	NC score	0.459363 (rank : 57)
Query Neighborhood Hits	314	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

SYT7_HUMAN
θ value	2.88119e-14 (rank : 30)	NC score	0.776536 (rank : 22)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

DOC2A_MOUSE
θ value	3.76295e-14 (rank : 31)	NC score	0.778433 (rank : 17)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
θ value	4.91457e-14 (rank : 32)	NC score	0.777139 (rank : 21)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	90
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

P3C2A_MOUSE
θ value	4.91457e-14 (rank : 33)	NC score	0.457092 (rank : 58)
Query Neighborhood Hits	314	Target Neighborhood Hits	181	Shared Neighborhood Hits	76
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RP3A_MOUSE
θ value	4.91457e-14 (rank : 34)	NC score	0.754498 (rank : 38)
Query Neighborhood Hits	314	Target Neighborhood Hits	510	Shared Neighborhood Hits	131
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_HUMAN
θ value	6.41864e-14 (rank : 35)	NC score	0.758345 (rank : 34)
Query Neighborhood Hits	314	Target Neighborhood Hits	305	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT8_MOUSE
θ value	8.38298e-14 (rank : 36)	NC score	0.754716 (rank : 37)
Query Neighborhood Hits	314	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT4_HUMAN
θ value	6.00763e-12 (rank : 37)	NC score	0.761707 (rank : 31)
Query Neighborhood Hits	314	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT15_HUMAN
θ value	1.02475e-11 (rank : 38)	NC score	0.744954 (rank : 40)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

P3C2B_HUMAN
θ value	1.33837e-11 (rank : 39)	NC score	0.488090 (rank : 55)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

SYT4_MOUSE
θ value	2.28291e-11 (rank : 40)	NC score	0.759839 (rank : 33)
Query Neighborhood Hits	314	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

RASA2_MOUSE
θ value	6.64225e-11 (rank : 41)	NC score	0.445553 (rank : 59)
Query Neighborhood Hits	314	Target Neighborhood Hits	159	Shared Neighborhood Hits	73
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RIMS1_HUMAN
θ value	8.67504e-11 (rank : 42)	NC score	0.571731 (rank : 48)
Query Neighborhood Hits	314	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SYT12_HUMAN
θ value	2.52405e-10 (rank : 43)	NC score	0.755020 (rank : 36)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	3.29651e-10 (rank : 44)	NC score	0.757626 (rank : 35)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

RASA2_HUMAN
θ value	4.30538e-10 (rank : 45)	NC score	0.438640 (rank : 60)
Query Neighborhood Hits	314	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PCLO_HUMAN
θ value	7.34386e-10 (rank : 46)	NC score	0.498237 (rank : 54)
Query Neighborhood Hits	314	Target Neighborhood Hits	2046	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DOC2G_MOUSE
θ value	2.13673e-09 (rank : 47)	NC score	0.746717 (rank : 39)
Query Neighborhood Hits	314	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

PCLO_MOUSE
θ value	3.64472e-09 (rank : 48)	NC score	0.470789 (rank : 56)
Query Neighborhood Hits	314	Target Neighborhood Hits	2275	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KPCG_MOUSE
θ value	4.76016e-09 (rank : 49)	NC score	0.195996 (rank : 96)
Query Neighborhood Hits	314	Target Neighborhood Hits	1123	Shared Neighborhood Hits	98
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
θ value	6.21693e-09 (rank : 50)	NC score	0.196265 (rank : 95)
Query Neighborhood Hits	314	Target Neighborhood Hits	1126	Shared Neighborhood Hits	99
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

RIMS2_MOUSE
θ value	1.06045e-08 (rank : 51)	NC score	0.553780 (rank : 50)
Query Neighborhood Hits	314	Target Neighborhood Hits	376	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
θ value	1.80886e-08 (rank : 52)	NC score	0.559021 (rank : 49)
Query Neighborhood Hits	314	Target Neighborhood Hits	342	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

KPCB_HUMAN
θ value	6.87365e-08 (rank : 53)	NC score	0.177743 (rank : 101)
Query Neighborhood Hits	314	Target Neighborhood Hits	1121	Shared Neighborhood Hits	95
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT15_MOUSE
θ value	6.87365e-08 (rank : 54)	NC score	0.707385 (rank : 41)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

KPCB_MOUSE
θ value	1.53129e-07 (rank : 55)	NC score	0.179730 (rank : 99)
Query Neighborhood Hits	314	Target Neighborhood Hits	1117	Shared Neighborhood Hits	95
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
θ value	2.21117e-06 (rank : 56)	NC score	0.177453 (rank : 102)
Query Neighborhood Hits	314	Target Neighborhood Hits	1067	Shared Neighborhood Hits	96
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

FA62A_MOUSE
θ value	2.88788e-06 (rank : 57)	NC score	0.604501 (rank : 43)
Query Neighborhood Hits	314	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

KPCA_HUMAN
θ value	2.88788e-06 (rank : 58)	NC score	0.180236 (rank : 98)
Query Neighborhood Hits	314	Target Neighborhood Hits	1070	Shared Neighborhood Hits	96
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

FA62A_HUMAN
θ value	3.77169e-06 (rank : 59)	NC score	0.602414 (rank : 44)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RASL2_HUMAN
θ value	4.92598e-06 (rank : 60)	NC score	0.539546 (rank : 51)
Query Neighborhood Hits	314	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SLC2B_HUMAN
θ value	8.40245e-06 (rank : 61)	NC score	0.208626 (rank : 94)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

SYT14_MOUSE
θ value	8.40245e-06 (rank : 62)	NC score	0.597214 (rank : 45)
Query Neighborhood Hits	314	Target Neighborhood Hits	82	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RASA3_HUMAN
θ value	5.44631e-05 (rank : 63)	NC score	0.411121 (rank : 66)
Query Neighborhood Hits	314	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

TRI44_MOUSE
θ value	7.1131e-05 (rank : 64)	NC score	0.063029 (rank : 159)
Query Neighborhood Hits	314	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

RIMS4_MOUSE
θ value	9.29e-05 (rank : 65)	NC score	0.518778 (rank : 52)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
θ value	0.000121331 (rank : 66)	NC score	0.515365 (rank : 53)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

NED4L_HUMAN
θ value	0.000158464 (rank : 67)	NC score	0.293933 (rank : 76)
Query Neighborhood Hits	314	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NEDD4_MOUSE
θ value	0.000158464 (rank : 68)	NC score	0.258496 (rank : 83)
Query Neighborhood Hits	314	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SYT14_HUMAN
θ value	0.000158464 (rank : 69)	NC score	0.594564 (rank : 47)
Query Neighborhood Hits	314	Target Neighborhood Hits	81	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS3_MOUSE
θ value	0.00020696 (rank : 70)	NC score	0.429154 (rank : 64)
Query Neighborhood Hits	314	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RASA3_MOUSE
θ value	0.000270298 (rank : 71)	NC score	0.353738 (rank : 71)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

NEDD4_HUMAN
θ value	0.00035302 (rank : 72)	NC score	0.269827 (rank : 80)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	84
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

DYSF_HUMAN
θ value	0.000602161 (rank : 73)	NC score	0.325582 (rank : 72)
Query Neighborhood Hits	314	Target Neighborhood Hits	170	Shared Neighborhood Hits	94
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

UN13D_HUMAN
θ value	0.000602161 (rank : 74)	NC score	0.433604 (rank : 61)
Query Neighborhood Hits	314	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

NED4L_MOUSE
θ value	0.000786445 (rank : 75)	NC score	0.289885 (rank : 77)
Query Neighborhood Hits	314	Target Neighborhood Hits	231	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

DYSF_MOUSE
θ value	0.00102713 (rank : 76)	NC score	0.323647 (rank : 73)
Query Neighborhood Hits	314	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RIMS3_HUMAN
θ value	0.00102713 (rank : 77)	NC score	0.431056 (rank : 63)
Query Neighborhood Hits	314	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

NFM_HUMAN
θ value	0.00298849 (rank : 78)	NC score	0.031321 (rank : 249)
Query Neighborhood Hits	314	Target Neighborhood Hits	1328	Shared Neighborhood Hits	95
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RGS3_HUMAN
θ value	0.00298849 (rank : 79)	NC score	0.231804 (rank : 92)
Query Neighborhood Hits	314	Target Neighborhood Hits	1375	Shared Neighborhood Hits	157
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SOX12_HUMAN
θ value	0.00298849 (rank : 80)	NC score	0.023143 (rank : 280)
Query Neighborhood Hits	314	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

NP1L3_HUMAN
θ value	0.00509761 (rank : 81)	NC score	0.047378 (rank : 212)
Query Neighborhood Hits	314	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

RP1L1_HUMAN
θ value	0.00509761 (rank : 82)	NC score	0.056098 (rank : 183)
Query Neighborhood Hits	314	Target Neighborhood Hits	1072	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MYRIP_HUMAN
θ value	0.00665767 (rank : 83)	NC score	0.257901 (rank : 84)
Query Neighborhood Hits	314	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

SYT13_HUMAN
θ value	0.00665767 (rank : 84)	NC score	0.606715 (rank : 42)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	64
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

IF39_MOUSE
θ value	0.00869519 (rank : 85)	NC score	0.059869 (rank : 166)
Query Neighborhood Hits	314	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

ANR11_HUMAN
θ value	0.0113563 (rank : 86)	NC score	0.029295 (rank : 252)
Query Neighborhood Hits	314	Target Neighborhood Hits	1289	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CN155_HUMAN
θ value	0.0113563 (rank : 87)	NC score	0.069900 (rank : 154)
Query Neighborhood Hits	314	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

HTSF1_MOUSE
θ value	0.0148317 (rank : 88)	NC score	0.043657 (rank : 218)
Query Neighborhood Hits	314	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MARCS_HUMAN
θ value	0.0148317 (rank : 89)	NC score	0.078906 (rank : 145)
Query Neighborhood Hits	314	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MDN1_HUMAN
θ value	0.0148317 (rank : 90)	NC score	0.072690 (rank : 151)
Query Neighborhood Hits	314	Target Neighborhood Hits	662	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SMRC2_HUMAN
θ value	0.0148317 (rank : 91)	NC score	0.057471 (rank : 173)
Query Neighborhood Hits	314	Target Neighborhood Hits	499	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

CI082_HUMAN
θ value	0.0193708 (rank : 92)	NC score	0.046672 (rank : 213)
Query Neighborhood Hits	314	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

CPNE7_HUMAN
θ value	0.0193708 (rank : 93)	NC score	0.150771 (rank : 112)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SRCA_HUMAN
θ value	0.0193708 (rank : 94)	NC score	0.050940 (rank : 197)
Query Neighborhood Hits	314	Target Neighborhood Hits	380	Shared Neighborhood Hits	54
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

MYRIP_MOUSE
θ value	0.0252991 (rank : 95)	NC score	0.262732 (rank : 81)
Query Neighborhood Hits	314	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NFM_MOUSE
θ value	0.0252991 (rank : 96)	NC score	0.026960 (rank : 263)
Query Neighborhood Hits	314	Target Neighborhood Hits	1159	Shared Neighborhood Hits	68
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

CLIC6_MOUSE
θ value	0.0330416 (rank : 97)	NC score	0.027172 (rank : 261)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

DAXX_HUMAN
θ value	0.0330416 (rank : 98)	NC score	0.040363 (rank : 231)
Query Neighborhood Hits	314	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

E41L2_HUMAN
θ value	0.0330416 (rank : 99)	NC score	0.017633 (rank : 301)
Query Neighborhood Hits	314	Target Neighborhood Hits	287	Shared Neighborhood Hits	17
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

GNAS3_HUMAN
θ value	0.0330416 (rank : 100)	NC score	0.079477 (rank : 144)
Query Neighborhood Hits	314	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

LRRF1_MOUSE
θ value	0.0330416 (rank : 101)	NC score	0.053193 (rank : 187)
Query Neighborhood Hits	314	Target Neighborhood Hits	440	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MYST3_HUMAN
θ value	0.0330416 (rank : 102)	NC score	0.047526 (rank : 210)
Query Neighborhood Hits	314	Target Neighborhood Hits	772	Shared Neighborhood Hits	70
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFH_HUMAN
θ value	0.0330416 (rank : 103)	NC score	0.037201 (rank : 236)
Query Neighborhood Hits	314	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PININ_HUMAN
θ value	0.0330416 (rank : 104)	NC score	0.053634 (rank : 186)
Query Neighborhood Hits	314	Target Neighborhood Hits	753	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SMRC2_MOUSE
θ value	0.0330416 (rank : 105)	NC score	0.057187 (rank : 176)
Query Neighborhood Hits	314	Target Neighborhood Hits	487	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

GNAS3_MOUSE
θ value	0.0431538 (rank : 106)	NC score	0.085739 (rank : 141)
Query Neighborhood Hits	314	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

NOL3_MOUSE
θ value	0.0431538 (rank : 107)	NC score	0.072220 (rank : 152)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

PTPRG_HUMAN
θ value	0.0431538 (rank : 108)	NC score	0.014041 (rank : 320)
Query Neighborhood Hits	314	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RASL1_HUMAN
θ value	0.0431538 (rank : 109)	NC score	0.431260 (rank : 62)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	74
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

TRI44_HUMAN
θ value	0.0431538 (rank : 110)	NC score	0.048761 (rank : 204)
Query Neighborhood Hits	314	Target Neighborhood Hits	393	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

AFF1_HUMAN
θ value	0.0736092 (rank : 111)	NC score	0.058263 (rank : 171)
Query Neighborhood Hits	314	Target Neighborhood Hits	506	Shared Neighborhood Hits	45
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

GLU2B_HUMAN
θ value	0.0736092 (rank : 112)	NC score	0.051499 (rank : 194)
Query Neighborhood Hits	314	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

MELPH_HUMAN
θ value	0.0736092 (rank : 113)	NC score	0.249928 (rank : 86)
Query Neighborhood Hits	314	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

PININ_MOUSE
θ value	0.0736092 (rank : 114)	NC score	0.045953 (rank : 214)
Query Neighborhood Hits	314	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

AP3B2_HUMAN
θ value	0.0961366 (rank : 115)	NC score	0.026603 (rank : 264)
Query Neighborhood Hits	314	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

MELPH_MOUSE
θ value	0.0961366 (rank : 116)	NC score	0.244923 (rank : 88)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	26
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

SOX12_MOUSE
θ value	0.0961366 (rank : 117)	NC score	0.017711 (rank : 299)
Query Neighborhood Hits	314	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

MYST4_HUMAN
θ value	0.125558 (rank : 118)	NC score	0.043075 (rank : 220)
Query Neighborhood Hits	314	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

OXRP_HUMAN
θ value	0.125558 (rank : 119)	NC score	0.048456 (rank : 207)
Query Neighborhood Hits	314	Target Neighborhood Hits	544	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PEG3_MOUSE
θ value	0.125558 (rank : 120)	NC score	0.012890 (rank : 324)
Query Neighborhood Hits	314	Target Neighborhood Hits	1101	Shared Neighborhood Hits	89
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PK1L1_HUMAN
θ value	0.125558 (rank : 121)	NC score	0.032249 (rank : 246)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

PTPRG_MOUSE
θ value	0.125558 (rank : 122)	NC score	0.014499 (rank : 315)
Query Neighborhood Hits	314	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RFIP1_HUMAN
θ value	0.125558 (rank : 123)	NC score	0.162234 (rank : 108)
Query Neighborhood Hits	314	Target Neighborhood Hits	236	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

AFF4_MOUSE
θ value	0.163984 (rank : 124)	NC score	0.052427 (rank : 189)
Query Neighborhood Hits	314	Target Neighborhood Hits	581	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

NCKX1_HUMAN
θ value	0.163984 (rank : 125)	NC score	0.030164 (rank : 250)
Query Neighborhood Hits	314	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

NFH_MOUSE
θ value	0.163984 (rank : 126)	NC score	0.063082 (rank : 158)
Query Neighborhood Hits	314	Target Neighborhood Hits	2247	Shared Neighborhood Hits	152
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RFIP1_MOUSE
θ value	0.163984 (rank : 127)	NC score	0.166277 (rank : 105)
Query Neighborhood Hits	314	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SYT13_MOUSE
θ value	0.163984 (rank : 128)	NC score	0.595975 (rank : 46)
Query Neighborhood Hits	314	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

T2FA_HUMAN
θ value	0.163984 (rank : 129)	NC score	0.048699 (rank : 205)
Query Neighborhood Hits	314	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCOF_HUMAN
θ value	0.163984 (rank : 130)	NC score	0.047734 (rank : 209)
Query Neighborhood Hits	314	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

GON4L_HUMAN
θ value	0.21417 (rank : 131)	NC score	0.050516 (rank : 200)
Query Neighborhood Hits	314	Target Neighborhood Hits	555	Shared Neighborhood Hits	79
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

NFL_HUMAN
θ value	0.21417 (rank : 132)	NC score	0.023227 (rank : 278)
Query Neighborhood Hits	314	Target Neighborhood Hits	666	Shared Neighborhood Hits	42
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NUCL_MOUSE
θ value	0.21417 (rank : 133)	NC score	0.023162 (rank : 279)
Query Neighborhood Hits	314	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

GLU2B_MOUSE
θ value	0.279714 (rank : 134)	NC score	0.042426 (rank : 223)
Query Neighborhood Hits	314	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

IF4G1_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.022985 (rank : 281)
Query Neighborhood Hits	314	Target Neighborhood Hits	347	Shared Neighborhood Hits	23
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MYT1_HUMAN
θ value	0.279714 (rank : 136)	NC score	0.027992 (rank : 258)
Query Neighborhood Hits	314	Target Neighborhood Hits	475	Shared Neighborhood Hits	37
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NFL_MOUSE
θ value	0.279714 (rank : 137)	NC score	0.025253 (rank : 268)
Query Neighborhood Hits	314	Target Neighborhood Hits	695	Shared Neighborhood Hits	42
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

MYOF_HUMAN
θ value	0.365318 (rank : 138)	NC score	0.309709 (rank : 75)
Query Neighborhood Hits	314	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

SFR14_HUMAN
θ value	0.365318 (rank : 139)	NC score	0.022355 (rank : 283)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX01, O15071, O60369, Q5JPH7, Q8WUF7	Gene names	SFRS14, KIAA0365
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

TRPS1_MOUSE
θ value	0.365318 (rank : 140)	NC score	0.024397 (rank : 272)
Query Neighborhood Hits	314	Target Neighborhood Hits	609	Shared Neighborhood Hits	26
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

BASP_MOUSE
θ value	0.47712 (rank : 141)	NC score	0.056374 (rank : 179)
Query Neighborhood Hits	314	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCL7C_MOUSE
θ value	0.47712 (rank : 142)	NC score	0.033726 (rank : 242)
Query Neighborhood Hits	314	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

CD2L1_MOUSE
θ value	0.47712 (rank : 143)	NC score	0.014648 (rank : 312)
Query Neighborhood Hits	314	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

FYCO1_MOUSE
θ value	0.47712 (rank : 144)	NC score	0.009382 (rank : 341)
Query Neighborhood Hits	314	Target Neighborhood Hits	1059	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

LR37B_HUMAN
θ value	0.47712 (rank : 145)	NC score	0.014125 (rank : 318)
Query Neighborhood Hits	314	Target Neighborhood Hits	392	Shared Neighborhood Hits	18
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MARCS_MOUSE
θ value	0.47712 (rank : 146)	NC score	0.048398 (rank : 208)
Query Neighborhood Hits	314	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

PELP1_HUMAN
θ value	0.47712 (rank : 147)	NC score	0.039199 (rank : 233)
Query Neighborhood Hits	314	Target Neighborhood Hits	596	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

RASL1_MOUSE
θ value	0.47712 (rank : 148)	NC score	0.419445 (rank : 65)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RFIP2_HUMAN
θ value	0.47712 (rank : 149)	NC score	0.320390 (rank : 74)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

STK36_HUMAN
θ value	0.47712 (rank : 150)	NC score	0.008705 (rank : 346)
Query Neighborhood Hits	314	Target Neighborhood Hits	896	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

ZBT17_HUMAN
θ value	0.47712 (rank : 151)	NC score	-0.004175 (rank : 384)
Query Neighborhood Hits	314	Target Neighborhood Hits	925	Shared Neighborhood Hits	25
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

AFF4_HUMAN
θ value	0.62314 (rank : 152)	NC score	0.052001 (rank : 192)
Query Neighborhood Hits	314	Target Neighborhood Hits	611	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CHIC1_HUMAN
θ value	0.62314 (rank : 153)	NC score	0.021444 (rank : 289)
Query Neighborhood Hits	314	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VXU3	Gene names	CHIC1, BRX
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

LSP1_HUMAN
θ value	0.62314 (rank : 154)	NC score	0.051504 (rank : 193)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

RPGR1_MOUSE
θ value	0.62314 (rank : 155)	NC score	0.048486 (rank : 206)
Query Neighborhood Hits	314	Target Neighborhood Hits	713	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ACRBP_HUMAN
θ value	0.813845 (rank : 156)	NC score	0.025574 (rank : 267)
Query Neighborhood Hits	314	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

ALEX_MOUSE
θ value	0.813845 (rank : 157)	NC score	0.037154 (rank : 237)
Query Neighborhood Hits	314	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

AMPH_HUMAN
θ value	0.813845 (rank : 158)	NC score	0.041066 (rank : 229)
Query Neighborhood Hits	314	Target Neighborhood Hits	455	Shared Neighborhood Hits	63
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CBP_HUMAN
θ value	0.813845 (rank : 159)	NC score	0.036634 (rank : 238)
Query Neighborhood Hits	314	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CCDC9_MOUSE
θ value	0.813845 (rank : 160)	NC score	0.037562 (rank : 235)
Query Neighborhood Hits	314	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CLSPN_HUMAN
θ value	0.813845 (rank : 161)	NC score	0.027579 (rank : 259)
Query Neighborhood Hits	314	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

I28RA_HUMAN
θ value	0.813845 (rank : 162)	NC score	0.021536 (rank : 287)
Query Neighborhood Hits	314	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

IF2P_HUMAN
θ value	0.813845 (rank : 163)	NC score	0.019287 (rank : 292)
Query Neighborhood Hits	314	Target Neighborhood Hits	889	Shared Neighborhood Hits	46
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MDC1_HUMAN
θ value	0.813845 (rank : 164)	NC score	0.057288 (rank : 174)
Query Neighborhood Hits	314	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NEST_HUMAN
θ value	0.813845 (rank : 165)	NC score	0.037988 (rank : 234)
Query Neighborhood Hits	314	Target Neighborhood Hits	1305	Shared Neighborhood Hits	105
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PABP2_HUMAN
θ value	0.813845 (rank : 166)	NC score	0.021903 (rank : 286)
Query Neighborhood Hits	314	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

41_MOUSE
θ value	1.06291 (rank : 167)	NC score	0.014858 (rank : 310)
Query Neighborhood Hits	314	Target Neighborhood Hits	184	Shared Neighborhood Hits	26
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

CAC1F_HUMAN
θ value	1.06291 (rank : 168)	NC score	0.006358 (rank : 360)
Query Neighborhood Hits	314	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CBP_MOUSE
θ value	1.06291 (rank : 169)	NC score	0.041186 (rank : 227)
Query Neighborhood Hits	314	Target Neighborhood Hits	1051	Shared Neighborhood Hits	58
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDX21_MOUSE
θ value	1.06291 (rank : 170)	NC score	0.011243 (rank : 330)
Query Neighborhood Hits	314	Target Neighborhood Hits	350	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

GTF2I_HUMAN
θ value	1.06291 (rank : 171)	NC score	0.028133 (rank : 257)
Query Neighborhood Hits	314	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

ITSN2_MOUSE
θ value	1.06291 (rank : 172)	NC score	0.123764 (rank : 122)
Query Neighborhood Hits	314	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NP1L3_MOUSE
θ value	1.06291 (rank : 173)	NC score	0.033191 (rank : 243)
Query Neighborhood Hits	314	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PEG3_HUMAN
θ value	1.06291 (rank : 174)	NC score	-0.000389 (rank : 381)
Query Neighborhood Hits	314	Target Neighborhood Hits	800	Shared Neighborhood Hits	30
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

TF3C2_HUMAN
θ value	1.06291 (rank : 175)	NC score	0.017850 (rank : 298)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

AP3B2_MOUSE
θ value	1.38821 (rank : 176)	NC score	0.026262 (rank : 265)
Query Neighborhood Hits	314	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

BAT2_MOUSE
θ value	1.38821 (rank : 177)	NC score	0.045253 (rank : 216)
Query Neighborhood Hits	314	Target Neighborhood Hits	947	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CENPB_MOUSE
θ value	1.38821 (rank : 178)	NC score	0.025028 (rank : 270)
Query Neighborhood Hits	314	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DNL1_HUMAN
θ value	1.38821 (rank : 179)	NC score	0.023918 (rank : 275)
Query Neighborhood Hits	314	Target Neighborhood Hits	216	Shared Neighborhood Hits	28
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

HIRP3_HUMAN
θ value	1.38821 (rank : 180)	NC score	0.029892 (rank : 251)
Query Neighborhood Hits	314	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

ITSN2_HUMAN
θ value	1.38821 (rank : 181)	NC score	0.137293 (rank : 121)
Query Neighborhood Hits	314	Target Neighborhood Hits	1173	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYST3_MOUSE
θ value	1.38821 (rank : 182)	NC score	0.047442 (rank : 211)
Query Neighborhood Hits	314	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

TULP1_MOUSE
θ value	1.38821 (rank : 183)	NC score	0.016924 (rank : 304)
Query Neighborhood Hits	314	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ARI3A_HUMAN
θ value	1.81305 (rank : 184)	NC score	0.017430 (rank : 302)
Query Neighborhood Hits	314	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

BAT2_HUMAN
θ value	1.81305 (rank : 185)	NC score	0.045894 (rank : 215)
Query Neighborhood Hits	314	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CEP35_HUMAN
θ value	1.81305 (rank : 186)	NC score	0.027046 (rank : 262)
Query Neighborhood Hits	314	Target Neighborhood Hits	811	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CHSS3_HUMAN
θ value	1.81305 (rank : 187)	NC score	0.009679 (rank : 338)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CPNE4_HUMAN
θ value	1.81305 (rank : 188)	NC score	0.095651 (rank : 130)
Query Neighborhood Hits	314	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	1.81305 (rank : 189)	NC score	0.091681 (rank : 137)
Query Neighborhood Hits	314	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CXA8_HUMAN
θ value	1.81305 (rank : 190)	NC score	0.005956 (rank : 361)
Query Neighborhood Hits	314	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

NSBP1_MOUSE
θ value	1.81305 (rank : 191)	NC score	0.069821 (rank : 155)
Query Neighborhood Hits	314	Target Neighborhood Hits	681	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PABP2_MOUSE
θ value	1.81305 (rank : 192)	NC score	0.018617 (rank : 295)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PTMA_MOUSE
θ value	1.81305 (rank : 193)	NC score	0.050765 (rank : 199)
Query Neighborhood Hits	314	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

RAI1_HUMAN
θ value	1.81305 (rank : 194)	NC score	0.028143 (rank : 256)
Query Neighborhood Hits	314	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TBX3_MOUSE
θ value	1.81305 (rank : 195)	NC score	0.005931 (rank : 362)
Query Neighborhood Hits	314	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

TCAL3_MOUSE
θ value	1.81305 (rank : 196)	NC score	0.033010 (rank : 244)
Query Neighborhood Hits	314	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

ATF6A_HUMAN
θ value	2.36792 (rank : 197)	NC score	0.018263 (rank : 297)
Query Neighborhood Hits	314	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CLMN_HUMAN
θ value	2.36792 (rank : 198)	NC score	0.014391 (rank : 316)
Query Neighborhood Hits	314	Target Neighborhood Hits	205	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

DGKK_HUMAN
θ value	2.36792 (rank : 199)	NC score	0.028723 (rank : 255)
Query Neighborhood Hits	314	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

FAM9A_HUMAN
θ value	2.36792 (rank : 200)	NC score	0.026094 (rank : 266)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

NCOA6_HUMAN
θ value	2.36792 (rank : 201)	NC score	0.035630 (rank : 240)
Query Neighborhood Hits	314	Target Neighborhood Hits	1202	Shared Neighborhood Hits	65
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	2.36792 (rank : 202)	NC score	0.029208 (rank : 253)
Query Neighborhood Hits	314	Target Neighborhood Hits	1076	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PRB3_HUMAN
θ value	2.36792 (rank : 203)	NC score	0.039288 (rank : 232)
Query Neighborhood Hits	314	Target Neighborhood Hits	318	Shared Neighborhood Hits	25
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

RBM19_HUMAN
θ value	2.36792 (rank : 204)	NC score	0.008448 (rank : 348)
Query Neighborhood Hits	314	Target Neighborhood Hits	331	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

RGP1_HUMAN
θ value	2.36792 (rank : 205)	NC score	0.021450 (rank : 288)
Query Neighborhood Hits	314	Target Neighborhood Hits	124	Shared Neighborhood Hits	12
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

TRPS1_HUMAN
θ value	2.36792 (rank : 206)	NC score	0.017705 (rank : 300)
Query Neighborhood Hits	314	Target Neighborhood Hits	539	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

ZMY15_HUMAN
θ value	2.36792 (rank : 207)	NC score	0.024340 (rank : 273)
Query Neighborhood Hits	314	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

AFF1_MOUSE
θ value	3.0926 (rank : 208)	NC score	0.042477 (rank : 222)
Query Neighborhood Hits	314	Target Neighborhood Hits	351	Shared Neighborhood Hits	32
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ATBF1_HUMAN
θ value	3.0926 (rank : 209)	NC score	0.002348 (rank : 376)
Query Neighborhood Hits	314	Target Neighborhood Hits	1547	Shared Neighborhood Hits	53
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CCD27_MOUSE
θ value	3.0926 (rank : 210)	NC score	0.009422 (rank : 340)
Query Neighborhood Hits	314	Target Neighborhood Hits	461	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

FOG1_HUMAN
θ value	3.0926 (rank : 211)	NC score	0.001886 (rank : 379)
Query Neighborhood Hits	314	Target Neighborhood Hits	981	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

JHD3B_HUMAN
θ value	3.0926 (rank : 212)	NC score	0.007483 (rank : 356)
Query Neighborhood Hits	314	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

MYCL1_MOUSE
θ value	3.0926 (rank : 213)	NC score	0.009860 (rank : 337)
Query Neighborhood Hits	314	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

PAF49_HUMAN
θ value	3.0926 (rank : 214)	NC score	0.025225 (rank : 269)
Query Neighborhood Hits	314	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PRDM2_HUMAN
θ value	3.0926 (rank : 215)	NC score	0.010936 (rank : 332)
Query Neighborhood Hits	314	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SAPS3_MOUSE
θ value	3.0926 (rank : 216)	NC score	0.009153 (rank : 343)
Query Neighborhood Hits	314	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

SPT16_HUMAN
θ value	3.0926 (rank : 217)	NC score	0.015192 (rank : 309)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

VGF_HUMAN
θ value	3.0926 (rank : 218)	NC score	0.036054 (rank : 239)
Query Neighborhood Hits	314	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

ATS1_MOUSE
θ value	4.03905 (rank : 219)	NC score	-0.000012 (rank : 380)
Query Neighborhood Hits	314	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

BASP_HUMAN
θ value	4.03905 (rank : 220)	NC score	0.078595 (rank : 146)
Query Neighborhood Hits	314	Target Neighborhood Hits	321	Shared Neighborhood Hits	40
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CCDC9_HUMAN
θ value	4.03905 (rank : 221)	NC score	0.049567 (rank : 201)
Query Neighborhood Hits	314	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

CF010_HUMAN
θ value	4.03905 (rank : 222)	NC score	0.049077 (rank : 203)
Query Neighborhood Hits	314	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CJ026_MOUSE
θ value	4.03905 (rank : 223)	NC score	0.013911 (rank : 321)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

CLGN_MOUSE
θ value	4.03905 (rank : 224)	NC score	0.016198 (rank : 306)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

EP400_HUMAN
θ value	4.03905 (rank : 225)	NC score	0.014107 (rank : 319)
Query Neighborhood Hits	314	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ERC2_HUMAN
θ value	4.03905 (rank : 226)	NC score	0.007223 (rank : 357)
Query Neighborhood Hits	314	Target Neighborhood Hits	1156	Shared Neighborhood Hits	37
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	4.03905 (rank : 227)	NC score	0.007519 (rank : 355)
Query Neighborhood Hits	314	Target Neighborhood Hits	1166	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERCC6_HUMAN
θ value	4.03905 (rank : 228)	NC score	0.007785 (rank : 353)
Query Neighborhood Hits	314	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

FMN1A_MOUSE
θ value	4.03905 (rank : 229)	NC score	0.014206 (rank : 317)
Query Neighborhood Hits	314	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

K0152_MOUSE
θ value	4.03905 (rank : 230)	NC score	0.013475 (rank : 322)
Query Neighborhood Hits	314	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZQI3, Q8C6C3, Q8CD40, Q8CI91	Gene names	Kiaa0152
Domain Architecture	No domain graphic available
Description	Protein KIAA0152 precursor.

MBD1_MOUSE
θ value	4.03905 (rank : 231)	NC score	0.008589 (rank : 347)
Query Neighborhood Hits	314	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MYT1_MOUSE
θ value	4.03905 (rank : 232)	NC score	0.024601 (rank : 271)
Query Neighborhood Hits	314	Target Neighborhood Hits	385	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

P3C2G_MOUSE
θ value	4.03905 (rank : 233)	NC score	0.190241 (rank : 97)
Query Neighborhood Hits	314	Target Neighborhood Hits	113	Shared Neighborhood Hits	62
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PA24D_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.221214 (rank : 93)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PLEC1_HUMAN
θ value	4.03905 (rank : 235)	NC score	0.002969 (rank : 373)
Query Neighborhood Hits	314	Target Neighborhood Hits	1326	Shared Neighborhood Hits	42
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PTMA_HUMAN
θ value	4.03905 (rank : 236)	NC score	0.042798 (rank : 221)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

RAI1_MOUSE
θ value	4.03905 (rank : 237)	NC score	0.032899 (rank : 245)
Query Neighborhood Hits	314	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RPF53_HUMAN
θ value	4.03905 (rank : 238)	NC score	0.012831 (rank : 325)
Query Neighborhood Hits	314	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZS1, Q5VZT3, Q8NBA9, Q96L20	Gene names	PRAF1, PAF53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

RYR1_HUMAN
θ value	4.03905 (rank : 239)	NC score	0.011953 (rank : 329)
Query Neighborhood Hits	314	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

TMAP1_HUMAN
θ value	4.03905 (rank : 240)	NC score	0.041494 (rank : 226)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

TOPRS_MOUSE
θ value	4.03905 (rank : 241)	NC score	0.008120 (rank : 350)
Query Neighborhood Hits	314	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TXLNB_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.009651 (rank : 339)
Query Neighborhood Hits	314	Target Neighborhood Hits	640	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

ACINU_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.031411 (rank : 248)
Query Neighborhood Hits	314	Target Neighborhood Hits	712	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CAC1H_MOUSE
θ value	5.27518 (rank : 244)	NC score	0.005568 (rank : 363)
Query Neighborhood Hits	314	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CEP72_MOUSE
θ value	5.27518 (rank : 245)	NC score	0.005528 (rank : 364)
Query Neighborhood Hits	314	Target Neighborhood Hits	381	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

CLIC6_HUMAN
θ value	5.27518 (rank : 246)	NC score	0.034534 (rank : 241)
Query Neighborhood Hits	314	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CP053_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.014848 (rank : 311)
Query Neighborhood Hits	314	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

CRSP2_HUMAN
θ value	5.27518 (rank : 248)	NC score	0.022869 (rank : 282)
Query Neighborhood Hits	314	Target Neighborhood Hits	380	Shared Neighborhood Hits	29
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

CTCF_HUMAN
θ value	5.27518 (rank : 249)	NC score	-0.005599 (rank : 385)
Query Neighborhood Hits	314	Target Neighborhood Hits	764	Shared Neighborhood Hits	20
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

FGD5_HUMAN
θ value	5.27518 (rank : 250)	NC score	0.012771 (rank : 326)
Query Neighborhood Hits	314	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

JPH2_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.015819 (rank : 308)
Query Neighborhood Hits	314	Target Neighborhood Hits	639	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LIPS_HUMAN
θ value	5.27518 (rank : 252)	NC score	0.031793 (rank : 247)
Query Neighborhood Hits	314	Target Neighborhood Hits	314	Shared Neighborhood Hits	48
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

MYT1L_HUMAN
θ value	5.27518 (rank : 253)	NC score	0.019241 (rank : 293)
Query Neighborhood Hits	314	Target Neighborhood Hits	471	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

NASP_HUMAN
θ value	5.27518 (rank : 254)	NC score	0.091325 (rank : 138)
Query Neighborhood Hits	314	Target Neighborhood Hits	709	Shared Neighborhood Hits	107
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

OGFR_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.061666 (rank : 162)
Query Neighborhood Hits	314	Target Neighborhood Hits	1582	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PA24A_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.146701 (rank : 113)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	5.27518 (rank : 257)	NC score	0.159502 (rank : 109)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	64
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PRRT1_HUMAN
θ value	5.27518 (rank : 258)	NC score	0.024226 (rank : 274)
Query Neighborhood Hits	314	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

PRS10_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.002968 (rank : 374)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	5.27518 (rank : 260)	NC score	0.002968 (rank : 375)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

RECQ5_HUMAN
θ value	5.27518 (rank : 261)	NC score	0.020445 (rank : 290)
Query Neighborhood Hits	314	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SPRL1_MOUSE
θ value	5.27518 (rank : 262)	NC score	0.044437 (rank : 217)
Query Neighborhood Hits	314	Target Neighborhood Hits	403	Shared Neighborhood Hits	86
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TCOF_MOUSE
θ value	5.27518 (rank : 263)	NC score	0.043613 (rank : 219)
Query Neighborhood Hits	314	Target Neighborhood Hits	471	Shared Neighborhood Hits	39
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TF3C1_HUMAN
θ value	5.27518 (rank : 264)	NC score	0.011119 (rank : 331)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TTF2_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.006453 (rank : 359)
Query Neighborhood Hits	314	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

YTDC1_HUMAN
θ value	5.27518 (rank : 266)	NC score	0.041568 (rank : 225)
Query Neighborhood Hits	314	Target Neighborhood Hits	458	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZBT20_HUMAN
θ value	5.27518 (rank : 267)	NC score	-0.005748 (rank : 387)
Query Neighborhood Hits	314	Target Neighborhood Hits	835	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

ZBTB9_MOUSE
θ value	5.27518 (rank : 268)	NC score	-0.003340 (rank : 383)
Query Neighborhood Hits	314	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

B3A2_HUMAN
θ value	6.88961 (rank : 269)	NC score	0.004096 (rank : 368)
Query Neighborhood Hits	314	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

BCL6_MOUSE
θ value	6.88961 (rank : 270)	NC score	-0.005662 (rank : 386)
Query Neighborhood Hits	314	Target Neighborhood Hits	913	Shared Neighborhood Hits	28
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BRE1A_HUMAN
θ value	6.88961 (rank : 271)	NC score	0.004714 (rank : 366)
Query Neighborhood Hits	314	Target Neighborhood Hits	1071	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BSCL2_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.041620 (rank : 224)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

CCD96_HUMAN
θ value	6.88961 (rank : 273)	NC score	0.018615 (rank : 296)
Query Neighborhood Hits	314	Target Neighborhood Hits	595	Shared Neighborhood Hits	38
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CUTL2_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.012116 (rank : 328)
Query Neighborhood Hits	314	Target Neighborhood Hits	906	Shared Neighborhood Hits	48
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ELK1_MOUSE
θ value	6.88961 (rank : 275)	NC score	0.002081 (rank : 377)
Query Neighborhood Hits	314	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

EPC2_MOUSE
θ value	6.88961 (rank : 276)	NC score	0.005491 (rank : 365)
Query Neighborhood Hits	314	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

FILA_HUMAN
θ value	6.88961 (rank : 277)	NC score	0.017141 (rank : 303)
Query Neighborhood Hits	314	Target Neighborhood Hits	685	Shared Neighborhood Hits	45
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GOGA1_HUMAN
θ value	6.88961 (rank : 278)	NC score	0.007076 (rank : 358)
Query Neighborhood Hits	314	Target Neighborhood Hits	1222	Shared Neighborhood Hits	48
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

HD_HUMAN
θ value	6.88961 (rank : 279)	NC score	0.010866 (rank : 333)
Query Neighborhood Hits	314	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

IQEC3_MOUSE
θ value	6.88961 (rank : 280)	NC score	0.010464 (rank : 334)
Query Neighborhood Hits	314	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

JIP2_HUMAN
θ value	6.88961 (rank : 281)	NC score	0.016448 (rank : 305)
Query Neighborhood Hits	314	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

NOP14_MOUSE
θ value	6.88961 (rank : 282)	NC score	0.014594 (rank : 314)
Query Neighborhood Hits	314	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSD1_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.022240 (rank : 284)
Query Neighborhood Hits	314	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NTBP1_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.007854 (rank : 352)
Query Neighborhood Hits	314	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

RGP1_MOUSE
θ value	6.88961 (rank : 285)	NC score	0.015962 (rank : 307)
Query Neighborhood Hits	314	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

SMRC1_MOUSE
θ value	6.88961 (rank : 286)	NC score	0.040632 (rank : 230)
Query Neighborhood Hits	314	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

SRRM2_MOUSE
θ value	6.88961 (rank : 287)	NC score	0.056125 (rank : 182)
Query Neighborhood Hits	314	Target Neighborhood Hits	1470	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

VCX1_HUMAN
θ value	6.88961 (rank : 288)	NC score	0.023572 (rank : 276)
Query Neighborhood Hits	314	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

ZHX3_MOUSE
θ value	6.88961 (rank : 289)	NC score	0.003792 (rank : 370)
Query Neighborhood Hits	314	Target Neighborhood Hits	321	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ABCF1_HUMAN
θ value	8.99809 (rank : 290)	NC score	0.008832 (rank : 345)
Query Neighborhood Hits	314	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ACINU_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.041125 (rank : 228)
Query Neighborhood Hits	314	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CCD96_MOUSE
θ value	8.99809 (rank : 292)	NC score	0.020220 (rank : 291)
Query Neighborhood Hits	314	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CD2L1_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.010078 (rank : 336)
Query Neighborhood Hits	314	Target Neighborhood Hits	1467	Shared Neighborhood Hits	57
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CTR9_MOUSE
θ value	8.99809 (rank : 294)	NC score	0.018696 (rank : 294)
Query Neighborhood Hits	314	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CXA8_MOUSE
θ value	8.99809 (rank : 295)	NC score	0.004575 (rank : 367)
Query Neighborhood Hits	314	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P28236	Gene names	Gja8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

EHMT2_MOUSE
θ value	8.99809 (rank : 296)	NC score	0.007691 (rank : 354)
Query Neighborhood Hits	314	Target Neighborhood Hits	750	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FBX31_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.009251 (rank : 342)
Query Neighborhood Hits	314	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

GP152_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.008922 (rank : 344)
Query Neighborhood Hits	314	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

GSPT1_MOUSE
θ value	8.99809 (rank : 299)	NC score	0.003454 (rank : 371)
Query Neighborhood Hits	314	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R050, O88179	Gene names	Gspt1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog.

HTF4_HUMAN
θ value	8.99809 (rank : 300)	NC score	0.003937 (rank : 369)
Query Neighborhood Hits	314	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

K0319_MOUSE
θ value	8.99809 (rank : 301)	NC score	0.008216 (rank : 349)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

LRC50_HUMAN
θ value	8.99809 (rank : 302)	NC score	0.010128 (rank : 335)
Query Neighborhood Hits	314	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

MLL3_MOUSE
θ value	8.99809 (rank : 303)	NC score	0.022152 (rank : 285)
Query Neighborhood Hits	314	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NUCL_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.014610 (rank : 313)
Query Neighborhood Hits	314	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

PP2CG_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.012665 (rank : 327)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

PTMS_HUMAN
θ value	8.99809 (rank : 306)	NC score	0.028840 (rank : 254)
Query Neighborhood Hits	314	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

RUSC2_MOUSE
θ value	8.99809 (rank : 307)	NC score	0.012991 (rank : 323)
Query Neighborhood Hits	314	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRRM2_HUMAN
θ value	8.99809 (rank : 308)	NC score	0.049186 (rank : 202)
Query Neighborhood Hits	314	Target Neighborhood Hits	1296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SYN1_HUMAN
θ value	8.99809 (rank : 309)	NC score	0.023533 (rank : 277)
Query Neighborhood Hits	314	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TCF8_MOUSE
θ value	8.99809 (rank : 310)	NC score	-0.002451 (rank : 382)
Query Neighborhood Hits	314	Target Neighborhood Hits	1067	Shared Neighborhood Hits	48
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

TNNT3_MOUSE
θ value	8.99809 (rank : 311)	NC score	0.002995 (rank : 372)
Query Neighborhood Hits	314	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

TTBK1_HUMAN
θ value	8.99809 (rank : 312)	NC score	0.008097 (rank : 351)
Query Neighborhood Hits	314	Target Neighborhood Hits	1058	Shared Neighborhood Hits	52
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

WDR43_HUMAN
θ value	8.99809 (rank : 313)	NC score	0.002066 (rank : 378)
Query Neighborhood Hits	314	Target Neighborhood Hits	269	Shared Neighborhood Hits	8
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

XRCC1_MOUSE
θ value	8.99809 (rank : 314)	NC score	0.027194 (rank : 260)
Query Neighborhood Hits	314	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

AKA12_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.084169 (rank : 142)
Query Neighborhood Hits	314	Target Neighborhood Hits	825	Shared Neighborhood Hits	120
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BAIP3_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.384198 (rank : 67)
Query Neighborhood Hits	314	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.383407 (rank : 68)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	71
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BSN_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.054747 (rank : 184)
Query Neighborhood Hits	314	Target Neighborhood Hits	1537	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.061890 (rank : 161)
Query Neighborhood Hits	314	Target Neighborhood Hits	2057	Shared Neighborhood Hits	104
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CPNE1_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.119505 (rank : 123)
Query Neighborhood Hits	314	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.141460 (rank : 117)
Query Neighborhood Hits	314	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.138889 (rank : 120)
Query Neighborhood Hits	314	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.139880 (rank : 119)
Query Neighborhood Hits	314	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.163065 (rank : 107)
Query Neighborhood Hits	314	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.163281 (rank : 106)
Query Neighborhood Hits	314	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE5_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.151730 (rank : 110)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.151070 (rank : 111)
Query Neighborhood Hits	314	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE6_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.106851 (rank : 127)
Query Neighborhood Hits	314	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.105577 (rank : 128)
Query Neighborhood Hits	314	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE8_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.145593 (rank : 115)
Query Neighborhood Hits	314	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.142071 (rank : 116)
Query Neighborhood Hits	314	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

DAB2P_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.060236 (rank : 165)
Query Neighborhood Hits	314	Target Neighborhood Hits	303	Shared Neighborhood Hits	22
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.058360 (rank : 169)
Query Neighborhood Hits	314	Target Neighborhood Hits	284	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

ERIC1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.073760 (rank : 150)
Query Neighborhood Hits	314	Target Neighborhood Hits	364	Shared Neighborhood Hits	84
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

ITSN1_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.093825 (rank : 134)
Query Neighborhood Hits	314	Target Neighborhood Hits	1757	Shared Neighborhood Hits	128
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.094413 (rank : 131)
Query Neighborhood Hits	314	Target Neighborhood Hits	1669	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

IWS1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.092510 (rank : 136)
Query Neighborhood Hits	314	Target Neighborhood Hits	1241	Shared Neighborhood Hits	149
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.091048 (rank : 139)
Query Neighborhood Hits	314	Target Neighborhood Hits	1258	Shared Neighborhood Hits	156
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K0528_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.358038 (rank : 69)
Query Neighborhood Hits	314	Target Neighborhood Hits	96	Shared Neighborhood Hits	67
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.357490 (rank : 70)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

LEO1_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.071140 (rank : 153)
Query Neighborhood Hits	314	Target Neighborhood Hits	958	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.057209 (rank : 175)
Query Neighborhood Hits	314	Target Neighborhood Hits	946	Shared Neighborhood Hits	114
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NGAP_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.051066 (rank : 196)
Query Neighborhood Hits	314	Target Neighborhood Hits	517	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NIPBL_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.062063 (rank : 160)
Query Neighborhood Hits	314	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.057660 (rank : 172)
Query Neighborhood Hits	314	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

OGFR_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.053814 (rank : 185)
Query Neighborhood Hits	314	Target Neighborhood Hits	584	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OTOF_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.251433 (rank : 85)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.247401 (rank : 87)
Query Neighborhood Hits	314	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

P3C2G_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.169297 (rank : 103)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PA24B_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.140364 (rank : 118)
Query Neighborhood Hits	314	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24B_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.179599 (rank : 100)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24D_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.259743 (rank : 82)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24E_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.145869 (rank : 114)
Query Neighborhood Hits	314	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24E_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.167075 (rank : 104)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24F_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.088996 (rank : 140)
Query Neighborhood Hits	314	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PA24F_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.108309 (rank : 125)
Query Neighborhood Hits	314	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PI4KA_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.051462 (rank : 195)
Query Neighborhood Hits	314	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PK3C3_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.052295 (rank : 190)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.052188 (rank : 191)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3CA_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.059125 (rank : 167)
Query Neighborhood Hits	314	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.059077 (rank : 168)
Query Neighborhood Hits	314	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CB_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.056340 (rank : 180)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.056336 (rank : 181)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.057011 (rank : 177)
Query Neighborhood Hits	314	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.056947 (rank : 178)
Query Neighborhood Hits	314	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CG_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.060716 (rank : 163)
Query Neighborhood Hits	314	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.060675 (rank : 164)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PLCD1_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.109827 (rank : 124)
Query Neighborhood Hits	314	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.074463 (rank : 149)
Query Neighborhood Hits	314	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA1_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.065576 (rank : 157)
Query Neighborhood Hits	314	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

SMUF1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.094345 (rank : 132)
Query Neighborhood Hits	314	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.093514 (rank : 135)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.093833 (rank : 133)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SRRM1_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.050912 (rank : 198)
Query Neighborhood Hits	314	Target Neighborhood Hits	966	Shared Neighborhood Hits	77
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYGP1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.052521 (rank : 188)
Query Neighborhood Hits	314	Target Neighborhood Hits	589	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

SYT8_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.107118 (rank : 126)
Query Neighborhood Hits	314	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

TAC2N_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.289647 (rank : 78)
Query Neighborhood Hits	314	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.286952 (rank : 79)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TCAL5_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.077046 (rank : 147)
Query Neighborhood Hits	314	Target Neighborhood Hits	806	Shared Neighborhood Hits	128
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.080152 (rank : 143)
Query Neighborhood Hits	314	Target Neighborhood Hits	1037	Shared Neighborhood Hits	128
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.075049 (rank : 148)
Query Neighborhood Hits	314	Target Neighborhood Hits	793	Shared Neighborhood Hits	104
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.058341 (rank : 170)
Query Neighborhood Hits	314	Target Neighborhood Hits	828	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UN13A_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.239220 (rank : 90)
Query Neighborhood Hits	314	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.239265 (rank : 89)
Query Neighborhood Hits	314	Target Neighborhood Hits	217	Shared Neighborhood Hits	82
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.238838 (rank : 91)
Query Neighborhood Hits	314	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

WWC1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.068471 (rank : 156)
Query Neighborhood Hits	314	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

WWC1_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.098048 (rank : 129)
Query Neighborhood Hits	314	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

Hits sorted by NC score

SYTL1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	314	Target Neighborhood Hits	314	Shared Neighborhood Hits	314
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL1_HUMAN
NC score	0.962375 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	314	Target Neighborhood Hits	227	Shared Neighborhood Hits	125
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.921013 (rank : 3)	θ value	1.6097e-65 (rank : 6)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
NC score	0.920608 (rank : 4)	θ value	2.24614e-67 (rank : 5)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL2_MOUSE
NC score	0.919444 (rank : 5)	θ value	5.15425e-80 (rank : 4)
Query Neighborhood Hits	314	Target Neighborhood Hits	253	Shared Neighborhood Hits	109
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_HUMAN
NC score	0.917972 (rank : 6)	θ value	3.22841e-82 (rank : 3)
Query Neighborhood Hits	314	Target Neighborhood Hits	248	Shared Neighborhood Hits	107
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL5_MOUSE
NC score	0.909752 (rank : 7)	θ value	1.78386e-56 (rank : 8)
Query Neighborhood Hits	314	Target Neighborhood Hits	154	Shared Neighborhood Hits	94
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL5_HUMAN
NC score	0.908660 (rank : 8)	θ value	4.38363e-63 (rank : 7)
Query Neighborhood Hits	314	Target Neighborhood Hits	237	Shared Neighborhood Hits	104
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL3_MOUSE
NC score	0.899465 (rank : 9)	θ value	1.08726e-37 (rank : 9)
Query Neighborhood Hits	314	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT3_HUMAN
NC score	0.788415 (rank : 10)	θ value	6.40375e-22 (rank : 10)
Query Neighborhood Hits	314	Target Neighborhood Hits	145	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_MOUSE
NC score	0.787594 (rank : 11)	θ value	4.15078e-21 (rank : 11)
Query Neighborhood Hits	314	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT2_HUMAN
NC score	0.787457 (rank : 12)	θ value	7.0802e-21 (rank : 13)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	93
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
NC score	0.787438 (rank : 13)	θ value	5.42112e-21 (rank : 12)
Query Neighborhood Hits	314	Target Neighborhood Hits	143	Shared Neighborhood Hits	93
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_HUMAN
NC score	0.785036 (rank : 14)	θ value	2.06002e-20 (rank : 14)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
NC score	0.783462 (rank : 15)	θ value	6.62687e-19 (rank : 15)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT7_MOUSE
NC score	0.781274 (rank : 16)	θ value	2.7842e-17 (rank : 19)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

DOC2A_MOUSE
NC score	0.778433 (rank : 17)	θ value	3.76295e-14 (rank : 31)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

SYT1_HUMAN
NC score	0.778094 (rank : 18)	θ value	2.13179e-17 (rank : 17)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.778070 (rank : 19)	θ value	2.13179e-17 (rank : 18)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	94
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

DOC2B_MOUSE
NC score	0.777393 (rank : 20)	θ value	1.52774e-15 (rank : 22)
Query Neighborhood Hits	314	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2A_HUMAN
NC score	0.777139 (rank : 21)	θ value	4.91457e-14 (rank : 32)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	90
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT7_HUMAN
NC score	0.776536 (rank : 22)	θ value	2.88119e-14 (rank : 30)
Query Neighborhood Hits	314	Target Neighborhood Hits	137	Shared Neighborhood Hits	91
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

DOC2B_HUMAN
NC score	0.776265 (rank : 23)	θ value	4.44505e-15 (rank : 24)
Query Neighborhood Hits	314	Target Neighborhood Hits	150	Shared Neighborhood Hits	92
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT6_MOUSE
NC score	0.769892 (rank : 24)	θ value	8.10077e-17 (rank : 20)
Query Neighborhood Hits	314	Target Neighborhood Hits	132	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.769825 (rank : 25)	θ value	1.24977e-17 (rank : 16)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	93
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT11_MOUSE
NC score	0.767436 (rank : 26)	θ value	7.58209e-15 (rank : 25)
Query Neighborhood Hits	314	Target Neighborhood Hits	116	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
NC score	0.767337 (rank : 27)	θ value	9.90251e-15 (rank : 26)
Query Neighborhood Hits	314	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT10_HUMAN
NC score	0.764882 (rank : 28)	θ value	1.38178e-16 (rank : 21)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	91
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_HUMAN
NC score	0.764805 (rank : 29)	θ value	1.52774e-15 (rank : 23)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	92
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
NC score	0.762203 (rank : 30)	θ value	1.68911e-14 (rank : 28)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT4_HUMAN
NC score	0.761707 (rank : 31)	θ value	6.00763e-12 (rank : 37)
Query Neighborhood Hits	314	Target Neighborhood Hits	121	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT10_MOUSE
NC score	0.760570 (rank : 32)	θ value	1.29331e-14 (rank : 27)
Query Neighborhood Hits	314	Target Neighborhood Hits	133	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT4_MOUSE
NC score	0.759839 (rank : 33)	θ value	2.28291e-11 (rank : 40)
Query Neighborhood Hits	314	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

RP3A_HUMAN
NC score	0.758345 (rank : 34)	θ value	6.41864e-14 (rank : 35)
Query Neighborhood Hits	314	Target Neighborhood Hits	305	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT12_MOUSE
NC score	0.757626 (rank : 35)	θ value	3.29651e-10 (rank : 44)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_HUMAN
NC score	0.755020 (rank : 36)	θ value	2.52405e-10 (rank : 43)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT8_MOUSE
NC score	0.754716 (rank : 37)	θ value	8.38298e-14 (rank : 36)
Query Neighborhood Hits	314	Target Neighborhood Hits	94	Shared Neighborhood Hits	78
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

RP3A_MOUSE
NC score	0.754498 (rank : 38)	θ value	4.91457e-14 (rank : 34)
Query Neighborhood Hits	314	Target Neighborhood Hits	510	Shared Neighborhood Hits	131
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2G_MOUSE
NC score	0.746717 (rank : 39)	θ value	2.13673e-09 (rank : 47)
Query Neighborhood Hits	314	Target Neighborhood Hits	125	Shared Neighborhood Hits	84
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT15_HUMAN
NC score	0.744954 (rank : 40)	θ value	1.02475e-11 (rank : 38)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT15_MOUSE
NC score	0.707385 (rank : 41)	θ value	6.87365e-08 (rank : 54)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT13_HUMAN
NC score	0.606715 (rank : 42)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	64
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

FA62A_MOUSE
NC score	0.604501 (rank : 43)	θ value	2.88788e-06 (rank : 57)
Query Neighborhood Hits	314	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_HUMAN
NC score	0.602414 (rank : 44)	θ value	3.77169e-06 (rank : 59)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

SYT14_MOUSE
NC score	0.597214 (rank : 45)	θ value	8.40245e-06 (rank : 62)
Query Neighborhood Hits	314	Target Neighborhood Hits	82	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT13_MOUSE
NC score	0.595975 (rank : 46)	θ value	0.163984 (rank : 128)
Query Neighborhood Hits	314	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
NC score	0.594564 (rank : 47)	θ value	0.000158464 (rank : 69)
Query Neighborhood Hits	314	Target Neighborhood Hits	81	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS1_HUMAN
NC score	0.571731 (rank : 48)	θ value	8.67504e-11 (rank : 42)
Query Neighborhood Hits	314	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
NC score	0.559021 (rank : 49)	θ value	1.80886e-08 (rank : 52)
Query Neighborhood Hits	314	Target Neighborhood Hits	342	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.553780 (rank : 50)	θ value	1.06045e-08 (rank : 51)
Query Neighborhood Hits	314	Target Neighborhood Hits	376	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RASL2_HUMAN
NC score	0.539546 (rank : 51)	θ value	4.92598e-06 (rank : 60)
Query Neighborhood Hits	314	Target Neighborhood Hits	161	Shared Neighborhood Hits	88
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RIMS4_MOUSE
NC score	0.518778 (rank : 52)	θ value	9.29e-05 (rank : 65)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.515365 (rank : 53)	θ value	0.000121331 (rank : 66)
Query Neighborhood Hits	314	Target Neighborhood Hits	76	Shared Neighborhood Hits	71
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

PCLO_HUMAN
NC score	0.498237 (rank : 54)	θ value	7.34386e-10 (rank : 46)
Query Neighborhood Hits	314	Target Neighborhood Hits	2046	Shared Neighborhood Hits	200
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

P3C2B_HUMAN
NC score	0.488090 (rank : 55)	θ value	1.33837e-11 (rank : 39)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PCLO_MOUSE
NC score	0.470789 (rank : 56)	θ value	3.64472e-09 (rank : 48)
Query Neighborhood Hits	314	Target Neighborhood Hits	2275	Shared Neighborhood Hits	198
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

P3C2A_HUMAN
NC score	0.459363 (rank : 57)	θ value	2.88119e-14 (rank : 29)
Query Neighborhood Hits	314	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.457092 (rank : 58)	θ value	4.91457e-14 (rank : 33)
Query Neighborhood Hits	314	Target Neighborhood Hits	181	Shared Neighborhood Hits	76
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

RASA2_MOUSE
NC score	0.445553 (rank : 59)	θ value	6.64225e-11 (rank : 41)
Query Neighborhood Hits	314	Target Neighborhood Hits	159	Shared Neighborhood Hits	73
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_HUMAN
NC score	0.438640 (rank : 60)	θ value	4.30538e-10 (rank : 45)
Query Neighborhood Hits	314	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

UN13D_HUMAN
NC score	0.433604 (rank : 61)	θ value	0.000602161 (rank : 74)
Query Neighborhood Hits	314	Target Neighborhood Hits	117	Shared Neighborhood Hits	76
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

RASL1_HUMAN
NC score	0.431260 (rank : 62)	θ value	0.0431538 (rank : 109)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	74
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RIMS3_HUMAN
NC score	0.431056 (rank : 63)	θ value	0.00102713 (rank : 77)
Query Neighborhood Hits	314	Target Neighborhood Hits	66	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.429154 (rank : 64)	θ value	0.00020696 (rank : 70)
Query Neighborhood Hits	314	Target Neighborhood Hits	67	Shared Neighborhood Hits	65
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RASL1_MOUSE
NC score	0.419445 (rank : 65)	θ value	0.47712 (rank : 148)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASA3_HUMAN
NC score	0.411121 (rank : 66)	θ value	5.44631e-05 (rank : 63)
Query Neighborhood Hits	314	Target Neighborhood Hits	166	Shared Neighborhood Hits	76
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

BAIP3_HUMAN
NC score	0.384198 (rank : 67)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	314	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
NC score	0.383407 (rank : 68)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	71
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

K0528_HUMAN
NC score	0.358038 (rank : 69)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	314	Target Neighborhood Hits	96	Shared Neighborhood Hits	67
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.357490 (rank : 70)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

RASA3_MOUSE
NC score	0.353738 (rank : 71)	θ value	0.000270298 (rank : 71)
Query Neighborhood Hits	314	Target Neighborhood Hits	144	Shared Neighborhood Hits	70
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

DYSF_HUMAN
NC score	0.325582 (rank : 72)	θ value	0.000602161 (rank : 73)
Query Neighborhood Hits	314	Target Neighborhood Hits	170	Shared Neighborhood Hits	94
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
NC score	0.323647 (rank : 73)	θ value	0.00102713 (rank : 76)
Query Neighborhood Hits	314	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

RFIP2_HUMAN
NC score	0.320390 (rank : 74)	θ value	0.47712 (rank : 149)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

MYOF_HUMAN
NC score	0.309709 (rank : 75)	θ value	0.365318 (rank : 138)
Query Neighborhood Hits	314	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

NED4L_HUMAN
NC score	0.293933 (rank : 76)	θ value	0.000158464 (rank : 67)
Query Neighborhood Hits	314	Target Neighborhood Hits	238	Shared Neighborhood Hits	87
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
NC score	0.289885 (rank : 77)	θ value	0.000786445 (rank : 75)
Query Neighborhood Hits	314	Target Neighborhood Hits	231	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

TAC2N_HUMAN
NC score	0.289647 (rank : 78)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	314	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
NC score	0.286952 (rank : 79)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

NEDD4_HUMAN
NC score	0.269827 (rank : 80)	θ value	0.00035302 (rank : 72)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	84
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

MYRIP_MOUSE
NC score	0.262732 (rank : 81)	θ value	0.0252991 (rank : 95)
Query Neighborhood Hits	314	Target Neighborhood Hits	207	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PA24D_MOUSE
NC score	0.259743 (rank : 82)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

NEDD4_MOUSE
NC score	0.258496 (rank : 83)	θ value	0.000158464 (rank : 68)
Query Neighborhood Hits	314	Target Neighborhood Hits	212	Shared Neighborhood Hits	83
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

MYRIP_HUMAN
NC score	0.257901 (rank : 84)	θ value	0.00665767 (rank : 83)
Query Neighborhood Hits	314	Target Neighborhood Hits	269	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OTOF_HUMAN
NC score	0.251433 (rank : 85)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MELPH_HUMAN
NC score	0.249928 (rank : 86)	θ value	0.0736092 (rank : 113)
Query Neighborhood Hits	314	Target Neighborhood Hits	145	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

OTOF_MOUSE
NC score	0.247401 (rank : 87)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	314	Target Neighborhood Hits	196	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

MELPH_MOUSE
NC score	0.244923 (rank : 88)	θ value	0.0961366 (rank : 116)
Query Neighborhood Hits	314	Target Neighborhood Hits	112	Shared Neighborhood Hits	26
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

UN13B_HUMAN
NC score	0.239265 (rank : 89)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	314	Target Neighborhood Hits	217	Shared Neighborhood Hits	82
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.239220 (rank : 90)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	314	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.238838 (rank : 91)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	314	Target Neighborhood Hits	210	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RGS3_HUMAN
NC score	0.231804 (rank : 92)	θ value	0.00298849 (rank : 79)
Query Neighborhood Hits	314	Target Neighborhood Hits	1375	Shared Neighborhood Hits	157
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PA24D_HUMAN
NC score	0.221214 (rank : 93)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SLC2B_HUMAN
NC score	0.208626 (rank : 94)	θ value	8.40245e-06 (rank : 61)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

KPCG_HUMAN
NC score	0.196265 (rank : 95)	θ value	6.21693e-09 (rank : 50)
Query Neighborhood Hits	314	Target Neighborhood Hits	1126	Shared Neighborhood Hits	99
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.195996 (rank : 96)	θ value	4.76016e-09 (rank : 49)
Query Neighborhood Hits	314	Target Neighborhood Hits	1123	Shared Neighborhood Hits	98
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

P3C2G_MOUSE
NC score	0.190241 (rank : 97)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	314	Target Neighborhood Hits	113	Shared Neighborhood Hits	62
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

KPCA_HUMAN
NC score	0.180236 (rank : 98)	θ value	2.88788e-06 (rank : 58)
Query Neighborhood Hits	314	Target Neighborhood Hits	1070	Shared Neighborhood Hits	96
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.179730 (rank : 99)	θ value	1.53129e-07 (rank : 55)
Query Neighborhood Hits	314	Target Neighborhood Hits	1117	Shared Neighborhood Hits	95
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

PA24B_MOUSE
NC score	0.179599 (rank : 100)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	314	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

KPCB_HUMAN
NC score	0.177743 (rank : 101)	θ value	6.87365e-08 (rank : 53)
Query Neighborhood Hits	314	Target Neighborhood Hits	1121	Shared Neighborhood Hits	95
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.177453 (rank : 102)	θ value	2.21117e-06 (rank : 56)
Query Neighborhood Hits	314	Target Neighborhood Hits	1067	Shared Neighborhood Hits	96
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

P3C2G_HUMAN
NC score	0.169297 (rank : 103)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PA24E_MOUSE
NC score	0.167075 (rank : 104)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RFIP1_MOUSE
NC score	0.166277 (rank : 105)	θ value	0.163984 (rank : 127)
Query Neighborhood Hits	314	Target Neighborhood Hits	152	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CPNE3_MOUSE
NC score	0.163281 (rank : 106)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	314	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_HUMAN
NC score	0.163065 (rank : 107)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	314	Target Neighborhood Hits	90	Shared Neighborhood Hits	53
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

RFIP1_HUMAN
NC score	0.162234 (rank : 108)	θ value	0.125558 (rank : 123)
Query Neighborhood Hits	314	Target Neighborhood Hits	236	Shared Neighborhood Hits	51
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PA24A_MOUSE
NC score	0.159502 (rank : 109)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	64
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE5_HUMAN
NC score	0.151730 (rank : 110)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
NC score	0.151070 (rank : 111)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	314	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE7_HUMAN
NC score	0.150771 (rank : 112)	θ value	0.0193708 (rank : 93)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

PA24A_HUMAN
NC score	0.146701 (rank : 113)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24E_HUMAN
NC score	0.145869 (rank : 114)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	314	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

CPNE8_HUMAN
NC score	0.145593 (rank : 115)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	314	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
NC score	0.142071 (rank : 116)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	314	Target Neighborhood Hits	85	Shared Neighborhood Hits	53
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE1_MOUSE
NC score	0.141460 (rank : 117)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	314	Target Neighborhood Hits	83	Shared Neighborhood Hits	52
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

PA24B_HUMAN
NC score	0.140364 (rank : 118)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	314	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

CPNE2_MOUSE
NC score	0.139880 (rank : 119)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	314	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_HUMAN
NC score	0.138889 (rank : 120)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	314	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

ITSN2_HUMAN
NC score	0.137293 (rank : 121)	θ value	1.38821 (rank : 181)
Query Neighborhood Hits	314	Target Neighborhood Hits	1173	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
NC score	0.123764 (rank : 122)	θ value	1.06291 (rank : 172)
Query Neighborhood Hits	314	Target Neighborhood Hits	1371	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

CPNE1_HUMAN
NC score	0.119505 (rank : 123)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	314	Target Neighborhood Hits	70	Shared Neighborhood Hits	49
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

PLCD1_HUMAN
NC score	0.109827 (rank : 124)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	314	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PA24F_MOUSE
NC score	0.108309 (rank : 125)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	314	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SYT8_HUMAN
NC score	0.107118 (rank : 126)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	314	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NBV8, Q9NSV9	Gene names	SYT8
Domain Architecture	No domain graphic available
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

CPNE6_HUMAN
NC score	0.106851 (rank : 127)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	314	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
NC score	0.105577 (rank : 128)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	314	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

WWC1_MOUSE
NC score	0.098048 (rank : 129)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	314	Target Neighborhood Hits	290	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

CPNE4_HUMAN
NC score	0.095651 (rank : 130)	θ value	1.81305 (rank : 188)
Query Neighborhood Hits	314	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

ITSN1_MOUSE
NC score	0.094413 (rank : 131)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	314	Target Neighborhood Hits	1669	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SMUF1_HUMAN
NC score	0.094345 (rank : 132)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	314	Target Neighborhood Hits	135	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF2_HUMAN
NC score	0.093833 (rank : 133)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

ITSN1_HUMAN
NC score	0.093825 (rank : 134)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	314	Target Neighborhood Hits	1757	Shared Neighborhood Hits	128
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SMUF1_MOUSE
NC score	0.093514 (rank : 135)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

IWS1_HUMAN
NC score	0.092510 (rank : 136)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	314	Target Neighborhood Hits	1241	Shared Neighborhood Hits	149
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CPNE4_MOUSE
NC score	0.091681 (rank : 137)	θ value	1.81305 (rank : 189)
Query Neighborhood Hits	314	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

NASP_HUMAN
NC score	0.091325 (rank : 138)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	314	Target Neighborhood Hits	709	Shared Neighborhood Hits	107
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

IWS1_MOUSE
NC score	0.091048 (rank : 139)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	314	Target Neighborhood Hits	1258	Shared Neighborhood Hits	156
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PA24F_HUMAN
NC score	0.088996 (rank : 140)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	314	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

GNAS3_MOUSE
NC score	0.085739 (rank : 141)	θ value	0.0431538 (rank : 106)
Query Neighborhood Hits	314	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

AKA12_HUMAN
NC score	0.084169 (rank : 142)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	314	Target Neighborhood Hits	825	Shared Neighborhood Hits	120
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TGON2_HUMAN
NC score	0.080152 (rank : 143)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	314	Target Neighborhood Hits	1037	Shared Neighborhood Hits	128
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

GNAS3_HUMAN
NC score	0.079477 (rank : 144)	θ value	0.0330416 (rank : 100)
Query Neighborhood Hits	314	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

MARCS_HUMAN
NC score	0.078906 (rank : 145)	θ value	0.0148317 (rank : 89)
Query Neighborhood Hits	314	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

BASP_HUMAN
NC score	0.078595 (rank : 146)	θ value	4.03905 (rank : 220)
Query Neighborhood Hits	314	Target Neighborhood Hits	321	Shared Neighborhood Hits	40
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

TCAL5_HUMAN
NC score	0.077046 (rank : 147)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	314	Target Neighborhood Hits	806	Shared Neighborhood Hits	128
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TXND2_HUMAN
NC score	0.075049 (rank : 148)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	314	Target Neighborhood Hits	793	Shared Neighborhood Hits	104
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PLCD1_MOUSE
NC score	0.074463 (rank : 149)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	314	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

ERIC1_HUMAN
NC score	0.073760 (rank : 150)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	314	Target Neighborhood Hits	364	Shared Neighborhood Hits	84
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

MDN1_HUMAN
NC score	0.072690 (rank : 151)	θ value	0.0148317 (rank : 90)
Query Neighborhood Hits	314	Target Neighborhood Hits	662	Shared Neighborhood Hits	83
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NOL3_MOUSE
NC score	0.072220 (rank : 152)	θ value	0.0431538 (rank : 107)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

LEO1_HUMAN
NC score	0.071140 (rank : 153)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	314	Target Neighborhood Hits	958	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CN155_HUMAN
NC score	0.069900 (rank : 154)	θ value	0.0113563 (rank : 87)
Query Neighborhood Hits	314	Target Neighborhood Hits	385	Shared Neighborhood Hits	41
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

NSBP1_MOUSE
NC score	0.069821 (rank : 155)	θ value	1.81305 (rank : 191)
Query Neighborhood Hits	314	Target Neighborhood Hits	681	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

WWC1_HUMAN
NC score	0.068471 (rank : 156)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	314	Target Neighborhood Hits	290	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX03, O94946, Q6MZX4, Q6Y2F8, Q7Z4G8, Q8WVM4, Q9BT29	Gene names	WWC1, KIAA0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA) (HBeAg-binding protein 3).

RASA1_HUMAN
NC score	0.065576 (rank : 157)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	314	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

NFH_MOUSE
NC score	0.063082 (rank : 158)	θ value	0.163984 (rank : 126)
Query Neighborhood Hits	314	Target Neighborhood Hits	2247	Shared Neighborhood Hits	152
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TRI44_MOUSE
NC score	0.063029 (rank : 159)	θ value	7.1131e-05 (rank : 64)
Query Neighborhood Hits	314	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

NIPBL_HUMAN
NC score	0.062063 (rank : 160)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	314	Target Neighborhood Hits	1311	Shared Neighborhood Hits	129
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

BSN_MOUSE
NC score	0.061890 (rank : 161)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	314	Target Neighborhood Hits	2057	Shared Neighborhood Hits	104
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

OGFR_HUMAN
NC score	0.061666 (rank : 162)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	314	Target Neighborhood Hits	1582	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PK3CG_HUMAN
NC score	0.060716 (rank : 163)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	314	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.060675 (rank : 164)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

DAB2P_HUMAN
NC score	0.060236 (rank : 165)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	314	Target Neighborhood Hits	303	Shared Neighborhood Hits	22
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

IF39_MOUSE
NC score	0.059869 (rank : 166)	θ value	0.00869519 (rank : 85)
Query Neighborhood Hits	314	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

PK3CA_HUMAN
NC score	0.059125 (rank : 167)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	314	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
NC score	0.059077 (rank : 168)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	314	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

DAB2P_MOUSE
NC score	0.058360 (rank : 169)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	314	Target Neighborhood Hits	284	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

TXND2_MOUSE
NC score	0.058341 (rank : 170)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	314	Target Neighborhood Hits	828	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AFF1_HUMAN
NC score	0.058263 (rank : 171)	θ value	0.0736092 (rank : 111)
Query Neighborhood Hits	314	Target Neighborhood Hits	506	Shared Neighborhood Hits	45
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NPBL_MOUSE
NC score	0.057660 (rank : 172)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	314	Target Neighborhood Hits	1041	Shared Neighborhood Hits	113
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SMRC2_HUMAN
NC score	0.057471 (rank : 173)	θ value	0.0148317 (rank : 91)
Query Neighborhood Hits	314	Target Neighborhood Hits	499	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MDC1_HUMAN
NC score	0.057288 (rank : 174)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	314	Target Neighborhood Hits	1446	Shared Neighborhood Hits	123
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

LEO1_MOUSE
NC score	0.057209 (rank : 175)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	314	Target Neighborhood Hits	946	Shared Neighborhood Hits	114
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SMRC2_MOUSE
NC score	0.057187 (rank : 176)	θ value	0.0330416 (rank : 105)
Query Neighborhood Hits	314	Target Neighborhood Hits	487	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PK3CD_HUMAN
NC score	0.057011 (rank : 177)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	314	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
NC score	0.056947 (rank : 178)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	314	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

BASP_MOUSE
NC score	0.056374 (rank : 179)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	314	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PK3CB_HUMAN
NC score	0.056340 (rank : 180)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	314	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
NC score	0.056336 (rank : 181)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

SRRM2_MOUSE
NC score	0.056125 (rank : 182)	θ value	6.88961 (rank : 287)
Query Neighborhood Hits	314	Target Neighborhood Hits	1470	Shared Neighborhood Hits	85
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RP1L1_HUMAN
NC score	0.056098 (rank : 183)	θ value	0.00509761 (rank : 82)
Query Neighborhood Hits	314	Target Neighborhood Hits	1072	Shared Neighborhood Hits	96
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

BSN_HUMAN
NC score	0.054747 (rank : 184)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	314	Target Neighborhood Hits	1537	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

OGFR_MOUSE
NC score	0.053814 (rank : 185)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	314	Target Neighborhood Hits	584	Shared Neighborhood Hits	90
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PININ_HUMAN
NC score	0.053634 (rank : 186)	θ value	0.0330416 (rank : 104)
Query Neighborhood Hits	314	Target Neighborhood Hits	753	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

LRRF1_MOUSE
NC score	0.053193 (rank : 187)	θ value	0.0330416 (rank : 101)
Query Neighborhood Hits	314	Target Neighborhood Hits	440	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

SYGP1_HUMAN
NC score	0.052521 (rank : 188)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	314	Target Neighborhood Hits	589	Shared Neighborhood Hits	38
SwissProt Accessions	Q96PV0, Q8TCS2, Q9UGE2	Gene names	SYNGAP1, KIAA1938
Domain Architecture
Description	Ras GTPase-activating protein SynGAP (Synaptic Ras-GTPase-activating protein 1) (Synaptic Ras-GAP 1) (Neuronal RasGAP).

AFF4_MOUSE
NC score	0.052427 (rank : 189)	θ value	0.163984 (rank : 124)
Query Neighborhood Hits	314	Target Neighborhood Hits	581	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

PK3C3_HUMAN
NC score	0.052295 (rank : 190)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3C3_MOUSE
NC score	0.052188 (rank : 191)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	314	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

AFF4_HUMAN
NC score	0.052001 (rank : 192)	θ value	0.62314 (rank : 152)
Query Neighborhood Hits	314	Target Neighborhood Hits	611	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

LSP1_HUMAN
NC score	0.051504 (rank : 193)	θ value	0.62314 (rank : 154)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	38
SwissProt Accessions	P33241, Q16096, Q9BUY8	Gene names	LSP1, WP34
Domain Architecture	No domain graphic available
Description	Lymphocyte-specific protein 1 (Protein pp52) (52 kDa phosphoprotein) (Lymphocyte-specific antigen WP34) (47 kDa actin-binding protein).

GLU2B_HUMAN
NC score	0.051499 (rank : 194)	θ value	0.0736092 (rank : 112)
Query Neighborhood Hits	314	Target Neighborhood Hits	377	Shared Neighborhood Hits	27
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

PI4KA_HUMAN
NC score	0.051462 (rank : 195)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	314	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

NGAP_HUMAN
NC score	0.051066 (rank : 196)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	314	Target Neighborhood Hits	517	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

SRCA_HUMAN
NC score	0.050940 (rank : 197)	θ value	0.0193708 (rank : 94)
Query Neighborhood Hits	314	Target Neighborhood Hits	380	Shared Neighborhood Hits	54
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SRRM1_MOUSE
NC score	0.050912 (rank : 198)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	314	Target Neighborhood Hits	966	Shared Neighborhood Hits	77
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PTMA_MOUSE
NC score	0.050765 (rank : 199)	θ value	1.81305 (rank : 193)
Query Neighborhood Hits	314	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

GON4L_HUMAN
NC score	0.050516 (rank : 200)	θ value	0.21417 (rank : 131)
Query Neighborhood Hits	314	Target Neighborhood Hits	555	Shared Neighborhood Hits	79
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

CCDC9_HUMAN
NC score	0.049567 (rank : 201)	θ value	4.03905 (rank : 221)
Query Neighborhood Hits	314	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y3X0	Gene names	CCDC9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

SRRM2_HUMAN
NC score	0.049186 (rank : 202)	θ value	8.99809 (rank : 308)
Query Neighborhood Hits	314	Target Neighborhood Hits	1296	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CF010_HUMAN
NC score	0.049077 (rank : 203)	θ value	4.03905 (rank : 222)
Query Neighborhood Hits	314	Target Neighborhood Hits	329	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

TRI44_HUMAN
NC score	0.048761 (rank : 204)	θ value	0.0431538 (rank : 110)
Query Neighborhood Hits	314	Target Neighborhood Hits	393	Shared Neighborhood Hits	33
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

T2FA_HUMAN
NC score	0.048699 (rank : 205)	θ value	0.163984 (rank : 129)
Query Neighborhood Hits	314	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

RPGR1_MOUSE
NC score	0.048486 (rank : 206)	θ value	0.62314 (rank : 155)
Query Neighborhood Hits	314	Target Neighborhood Hits	713	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

OXRP_HUMAN
NC score	0.048456 (rank : 207)	θ value	0.125558 (rank : 119)
Query Neighborhood Hits	314	Target Neighborhood Hits	544	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

MARCS_MOUSE
NC score	0.048398 (rank : 208)	θ value	0.47712 (rank : 146)
Query Neighborhood Hits	314	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

TCOF_HUMAN
NC score	0.047734 (rank : 209)	θ value	0.163984 (rank : 130)
Query Neighborhood Hits	314	Target Neighborhood Hits	543	Shared Neighborhood Hits	53
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

MYST3_HUMAN
NC score	0.047526 (rank : 210)	θ value	0.0330416 (rank : 102)
Query Neighborhood Hits	314	Target Neighborhood Hits	772	Shared Neighborhood Hits	70
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.047442 (rank : 211)	θ value	1.38821 (rank : 182)
Query Neighborhood Hits	314	Target Neighborhood Hits	688	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NP1L3_HUMAN
NC score	0.047378 (rank : 212)	θ value	0.00509761 (rank : 81)
Query Neighborhood Hits	314	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

CI082_HUMAN
NC score	0.046672 (rank : 213)	θ value	0.0193708 (rank : 92)
Query Neighborhood Hits	314	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

PININ_MOUSE
NC score	0.045953 (rank : 214)	θ value	0.0736092 (rank : 114)
Query Neighborhood Hits	314	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

BAT2_HUMAN
NC score	0.045894 (rank : 215)	θ value	1.81305 (rank : 185)
Query Neighborhood Hits	314	Target Neighborhood Hits	931	Shared Neighborhood Hits	64
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
NC score	0.045253 (rank : 216)	θ value	1.38821 (rank : 177)
Query Neighborhood Hits	314	Target Neighborhood Hits	947	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

SPRL1_MOUSE
NC score	0.044437 (rank : 217)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	314	Target Neighborhood Hits	403	Shared Neighborhood Hits	86
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

HTSF1_MOUSE
NC score	0.043657 (rank : 218)	θ value	0.0148317 (rank : 88)
Query Neighborhood Hits	314	Target Neighborhood Hits	425	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

TCOF_MOUSE
NC score	0.043613 (rank : 219)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	314	Target Neighborhood Hits	471	Shared Neighborhood Hits	39
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

MYST4_HUMAN
NC score	0.043075 (rank : 220)	θ value	0.125558 (rank : 118)
Query Neighborhood Hits	314	Target Neighborhood Hits	671	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PTMA_HUMAN
NC score	0.042798 (rank : 221)	θ value	4.03905 (rank : 236)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

AFF1_MOUSE
NC score	0.042477 (rank : 222)	θ value	3.0926 (rank : 208)
Query Neighborhood Hits	314	Target Neighborhood Hits	351	Shared Neighborhood Hits	32
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

GLU2B_MOUSE
NC score	0.042426 (rank : 223)	θ value	0.279714 (rank : 134)
Query Neighborhood Hits	314	Target Neighborhood Hits	357	Shared Neighborhood Hits	22
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

BSCL2_HUMAN
NC score	0.041620 (rank : 224)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	314	Target Neighborhood Hits	148	Shared Neighborhood Hits	50
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

YTDC1_HUMAN
NC score	0.041568 (rank : 225)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	314	Target Neighborhood Hits	458	Shared Neighborhood Hits	60
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

TMAP1_HUMAN
NC score	0.041494 (rank : 226)	θ value	4.03905 (rank : 240)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	21
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

CBP_MOUSE
NC score	0.041186 (rank : 227)	θ value	1.06291 (rank : 169)
Query Neighborhood Hits	314	Target Neighborhood Hits	1051	Shared Neighborhood Hits	58
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ACINU_HUMAN
NC score	0.041125 (rank : 228)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	314	Target Neighborhood Hits	828	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AMPH_HUMAN
NC score	0.041066 (rank : 229)	θ value	0.813845 (rank : 158)
Query Neighborhood Hits	314	Target Neighborhood Hits	455	Shared Neighborhood Hits	63
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

SMRC1_MOUSE
NC score	0.040632 (rank : 230)	θ value	6.88961 (rank : 286)
Query Neighborhood Hits	314	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

DAXX_HUMAN
NC score	0.040363 (rank : 231)	θ value	0.0330416 (rank : 98)
Query Neighborhood Hits	314	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

PRB3_HUMAN
NC score	0.039288 (rank : 232)	θ value	2.36792 (rank : 203)
Query Neighborhood Hits	314	Target Neighborhood Hits	318	Shared Neighborhood Hits	25
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PELP1_HUMAN
NC score	0.039199 (rank : 233)	θ value	0.47712 (rank : 147)
Query Neighborhood Hits	314	Target Neighborhood Hits	596	Shared Neighborhood Hits	44
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

NEST_HUMAN
NC score	0.037988 (rank : 234)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	314	Target Neighborhood Hits	1305	Shared Neighborhood Hits	105
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CCDC9_MOUSE
NC score	0.037562 (rank : 235)	θ value	0.813845 (rank : 160)
Query Neighborhood Hits	314	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	Q8VC31	Gene names	Ccdc9
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 9.

NFH_HUMAN
NC score	0.037201 (rank : 236)	θ value	0.0330416 (rank : 103)
Query Neighborhood Hits	314	Target Neighborhood Hits	1242	Shared Neighborhood Hits	80
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ALEX_MOUSE
NC score	0.037154 (rank : 237)	θ value	0.813845 (rank : 157)
Query Neighborhood Hits	314	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CBP_HUMAN
NC score	0.036634 (rank : 238)	θ value	0.813845 (rank : 159)
Query Neighborhood Hits	314	Target Neighborhood Hits	941	Shared Neighborhood Hits	55
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

VGF_HUMAN
NC score	0.036054 (rank : 239)	θ value	3.0926 (rank : 218)
Query Neighborhood Hits	314	Target Neighborhood Hits	167	Shared Neighborhood Hits	24
SwissProt Accessions	O15240	Gene names	VGF
Domain Architecture	No domain graphic available
Description	Neurosecretory protein VGF precursor.

NCOA6_HUMAN
NC score	0.035630 (rank : 240)	θ value	2.36792 (rank : 201)
Query Neighborhood Hits	314	Target Neighborhood Hits	1202	Shared Neighborhood Hits	65
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CLIC6_HUMAN
NC score	0.034534 (rank : 241)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	314	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

BCL7C_MOUSE
NC score	0.033726 (rank : 242)	θ value	0.47712 (rank : 142)
Query Neighborhood Hits	314	Target Neighborhood Hits	170	Shared Neighborhood Hits	18
SwissProt Accessions	O08664, Q99LS2	Gene names	Bcl7c
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member C (B-cell chronic lymphocytic leukemia/lymphoma 7C protein).

NP1L3_MOUSE
NC score	0.033191 (rank : 243)	θ value	1.06291 (rank : 173)
Query Neighborhood Hits	314	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

TCAL3_MOUSE
NC score	0.033010 (rank : 244)	θ value	1.81305 (rank : 196)
Query Neighborhood Hits	314	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

RAI1_MOUSE
NC score	0.032899 (rank : 245)	θ value	4.03905 (rank : 237)
Query Neighborhood Hits	314	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PK1L1_HUMAN
NC score	0.032249 (rank : 246)	θ value	0.125558 (rank : 121)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

LIPS_HUMAN
NC score	0.031793 (rank : 247)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	314	Target Neighborhood Hits	314	Shared Neighborhood Hits	48
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

ACINU_MOUSE
NC score	0.031411 (rank : 248)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	314	Target Neighborhood Hits	712	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

NFM_HUMAN
NC score	0.031321 (rank : 249)	θ value	0.00298849 (rank : 78)
Query Neighborhood Hits	314	Target Neighborhood Hits	1328	Shared Neighborhood Hits	95
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NCKX1_HUMAN
NC score	0.030164 (rank : 250)	θ value	0.163984 (rank : 125)
Query Neighborhood Hits	314	Target Neighborhood Hits	223	Shared Neighborhood Hits	27
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

HIRP3_HUMAN
NC score	0.029892 (rank : 251)	θ value	1.38821 (rank : 180)
Query Neighborhood Hits	314	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

ANR11_HUMAN
NC score	0.029295 (rank : 252)	θ value	0.0113563 (rank : 86)
Query Neighborhood Hits	314	Target Neighborhood Hits	1289	Shared Neighborhood Hits	81
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

NCOA6_MOUSE
NC score	0.029208 (rank : 253)	θ value	2.36792 (rank : 202)
Query Neighborhood Hits	314	Target Neighborhood Hits	1076	Shared Neighborhood Hits	55
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PTMS_HUMAN
NC score	0.028840 (rank : 254)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	314	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

DGKK_HUMAN
NC score	0.028723 (rank : 255)	θ value	2.36792 (rank : 199)
Query Neighborhood Hits	314	Target Neighborhood Hits	378	Shared Neighborhood Hits	38
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

RAI1_HUMAN
NC score	0.028143 (rank : 256)	θ value	1.81305 (rank : 194)
Query Neighborhood Hits	314	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

GTF2I_HUMAN
NC score	0.028133 (rank : 257)	θ value	1.06291 (rank : 171)
Query Neighborhood Hits	314	Target Neighborhood Hits	151	Shared Neighborhood Hits	40
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

MYT1_HUMAN
NC score	0.027992 (rank : 258)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	314	Target Neighborhood Hits	475	Shared Neighborhood Hits	37
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

CLSPN_HUMAN
NC score	0.027579 (rank : 259)	θ value	0.813845 (rank : 161)
Query Neighborhood Hits	314	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

XRCC1_MOUSE
NC score	0.027194 (rank : 260)	θ value	8.99809 (rank : 314)
Query Neighborhood Hits	314	Target Neighborhood Hits	242	Shared Neighborhood Hits	44
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CLIC6_MOUSE
NC score	0.027172 (rank : 261)	θ value	0.0330416 (rank : 97)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CEP35_HUMAN
NC score	0.027046 (rank : 262)	θ value	1.81305 (rank : 186)
Query Neighborhood Hits	314	Target Neighborhood Hits	811	Shared Neighborhood Hits	51
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NFM_MOUSE
NC score	0.026960 (rank : 263)	θ value	0.0252991 (rank : 96)
Query Neighborhood Hits	314	Target Neighborhood Hits	1159	Shared Neighborhood Hits	68
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

AP3B2_HUMAN
NC score	0.026603 (rank : 264)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	314	Target Neighborhood Hits	246	Shared Neighborhood Hits	27
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
NC score	0.026262 (rank : 265)	θ value	1.38821 (rank : 176)
Query Neighborhood Hits	314	Target Neighborhood Hits	246	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

FAM9A_HUMAN
NC score	0.026094 (rank : 266)	θ value	2.36792 (rank : 200)
Query Neighborhood Hits	314	Target Neighborhood Hits	138	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IZU1	Gene names	FAM9A
Domain Architecture	No domain graphic available
Description	Protein FAM9A.

ACRBP_HUMAN
NC score	0.025574 (rank : 267)	θ value	0.813845 (rank : 156)
Query Neighborhood Hits	314	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NEB7, Q9BY87	Gene names	ACRBP
Domain Architecture	No domain graphic available
Description	Acrosin-binding protein precursor (Proacrosin-binding protein sp32) (Cancer testis antigen OY-TES-1).

NFL_MOUSE
NC score	0.025253 (rank : 268)	θ value	0.279714 (rank : 137)
Query Neighborhood Hits	314	Target Neighborhood Hits	695	Shared Neighborhood Hits	42
SwissProt Accessions	P08551, Q8K0Z0	Gene names	Nefl, Nf68, Nfl
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

PAF49_HUMAN
NC score	0.025225 (rank : 269)	θ value	3.0926 (rank : 214)
Query Neighborhood Hits	314	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

CENPB_MOUSE
NC score	0.025028 (rank : 270)	θ value	1.38821 (rank : 178)
Query Neighborhood Hits	314	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

MYT1_MOUSE
NC score	0.024601 (rank : 271)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	314	Target Neighborhood Hits	385	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

TRPS1_MOUSE
NC score	0.024397 (rank : 272)	θ value	0.365318 (rank : 140)
Query Neighborhood Hits	314	Target Neighborhood Hits	609	Shared Neighborhood Hits	26
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

ZMY15_HUMAN
NC score	0.024340 (rank : 273)	θ value	2.36792 (rank : 207)
Query Neighborhood Hits	314	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

PRRT1_HUMAN
NC score	0.024226 (rank : 274)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	314	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	Q99946, Q96DW3, Q96NQ8	Gene names	PRRT1, C6orf31, NG5
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 1.

DNL1_HUMAN
NC score	0.023918 (rank : 275)	θ value	1.38821 (rank : 179)
Query Neighborhood Hits	314	Target Neighborhood Hits	216	Shared Neighborhood Hits	28
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

VCX1_HUMAN
NC score	0.023572 (rank : 276)	θ value	6.88961 (rank : 288)
Query Neighborhood Hits	314	Target Neighborhood Hits	129	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

SYN1_HUMAN
NC score	0.023533 (rank : 277)	θ value	8.99809 (rank : 309)
Query Neighborhood Hits	314	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

NFL_HUMAN
NC score	0.023227 (rank : 278)	θ value	0.21417 (rank : 132)
Query Neighborhood Hits	314	Target Neighborhood Hits	666	Shared Neighborhood Hits	42
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

NUCL_MOUSE
NC score	0.023162 (rank : 279)	θ value	0.21417 (rank : 133)
Query Neighborhood Hits	314	Target Neighborhood Hits	425	Shared Neighborhood Hits	25
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

SOX12_HUMAN
NC score	0.023143 (rank : 280)	θ value	0.00298849 (rank : 80)
Query Neighborhood Hits	314	Target Neighborhood Hits	111	Shared Neighborhood Hits	9
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

IF4G1_HUMAN
NC score	0.022985 (rank : 281)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	314	Target Neighborhood Hits	347	Shared Neighborhood Hits	23
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

CRSP2_HUMAN
NC score	0.022869 (rank : 282)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	314	Target Neighborhood Hits	380	Shared Neighborhood Hits	29
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

SFR14_HUMAN
NC score	0.022355 (rank : 283)	θ value	0.365318 (rank : 139)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IX01, O15071, O60369, Q5JPH7, Q8WUF7	Gene names	SFRS14, KIAA0365
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

NSD1_HUMAN
NC score	0.022240 (rank : 284)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	314	Target Neighborhood Hits	427	Shared Neighborhood Hits	38
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MLL3_MOUSE
NC score	0.022152 (rank : 285)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	314	Target Neighborhood Hits	1399	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PABP2_HUMAN
NC score	0.021903 (rank : 286)	θ value	0.813845 (rank : 166)
Query Neighborhood Hits	314	Target Neighborhood Hits	212	Shared Neighborhood Hits	12
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

I28RA_HUMAN
NC score	0.021536 (rank : 287)	θ value	0.813845 (rank : 162)
Query Neighborhood Hits	314	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IU57, Q6ZML8, Q8IZI7, Q8IZI8	Gene names	IL28RA, IFNLR1, LICR2
Domain Architecture	No domain graphic available
Description	Interleukin-28 receptor alpha chain precursor (IL-28R-alpha) (IL-28RA) (Cytokine receptor family 2 member 12) (Cytokine receptor class-II member 12) (CRF2-12) (Interferon lambda receptor 1) (IFN-lambda R1) (Likely interleukin or cytokine receptor 2).

RGP1_HUMAN
NC score	0.021450 (rank : 288)	θ value	2.36792 (rank : 205)
Query Neighborhood Hits	314	Target Neighborhood Hits	124	Shared Neighborhood Hits	12
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CHIC1_HUMAN
NC score	0.021444 (rank : 289)	θ value	0.62314 (rank : 153)
Query Neighborhood Hits	314	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VXU3	Gene names	CHIC1, BRX
Domain Architecture	No domain graphic available
Description	Cysteine-rich hydrophobic domain 1 protein (Brain X-linked protein).

RECQ5_HUMAN
NC score	0.020445 (rank : 290)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	314	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

CCD96_MOUSE
NC score	0.020220 (rank : 291)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	314	Target Neighborhood Hits	704	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

IF2P_HUMAN
NC score	0.019287 (rank : 292)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	314	Target Neighborhood Hits	889	Shared Neighborhood Hits	46
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MYT1L_HUMAN
NC score	0.019241 (rank : 293)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	314	Target Neighborhood Hits	471	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

CTR9_MOUSE
NC score	0.018696 (rank : 294)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	314	Target Neighborhood Hits	427	Shared Neighborhood Hits	31
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

PABP2_MOUSE
NC score	0.018617 (rank : 295)	θ value	1.81305 (rank : 192)
Query Neighborhood Hits	314	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

CCD96_HUMAN
NC score	0.018615 (rank : 296)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	314	Target Neighborhood Hits	595	Shared Neighborhood Hits	38
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ATF6A_HUMAN
NC score	0.018263 (rank : 297)	θ value	2.36792 (rank : 197)
Query Neighborhood Hits	314	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

TF3C2_HUMAN
NC score	0.017850 (rank : 298)	θ value	1.06291 (rank : 175)
Query Neighborhood Hits	314	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

SOX12_MOUSE
NC score	0.017711 (rank : 299)	θ value	0.0961366 (rank : 117)
Query Neighborhood Hits	314	Target Neighborhood Hits	98	Shared Neighborhood Hits	5
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

TRPS1_HUMAN
NC score	0.017705 (rank : 300)	θ value	2.36792 (rank : 206)
Query Neighborhood Hits	314	Target Neighborhood Hits	539	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

E41L2_HUMAN
NC score	0.017633 (rank : 301)	θ value	0.0330416 (rank : 99)
Query Neighborhood Hits	314	Target Neighborhood Hits	287	Shared Neighborhood Hits	17
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ARI3A_HUMAN
NC score	0.017430 (rank : 302)	θ value	1.81305 (rank : 184)
Query Neighborhood Hits	314	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

FILA_HUMAN
NC score	0.017141 (rank : 303)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	314	Target Neighborhood Hits	685	Shared Neighborhood Hits	45
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

TULP1_MOUSE
NC score	0.016924 (rank : 304)	θ value	1.38821 (rank : 183)
Query Neighborhood Hits	314	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

JIP2_HUMAN
NC score	0.016448 (rank : 305)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	314	Target Neighborhood Hits	288	Shared Neighborhood Hits	21
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

CLGN_MOUSE
NC score	0.016198 (rank : 306)	θ value	4.03905 (rank : 224)
Query Neighborhood Hits	314	Target Neighborhood Hits	142	Shared Neighborhood Hits	36
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

RGP1_MOUSE
NC score	0.015962 (rank : 307)	θ value	6.88961 (rank : 285)
Query Neighborhood Hits	314	Target Neighborhood Hits	105	Shared Neighborhood Hits	14
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

JPH2_HUMAN
NC score	0.015819 (rank : 308)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	314	Target Neighborhood Hits	639	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SPT16_HUMAN
NC score	0.015192 (rank : 309)	θ value	3.0926 (rank : 217)
Query Neighborhood Hits	314	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5B9, Q6GMT8, Q6P2F1, Q6PJM1, Q9NRX0	Gene names	SUPT16H, FACT140, FACTP140
Domain Architecture	No domain graphic available
Description	FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16) (hSPT16) (FACT 140 kDa subunit) (FACTp140) (Chromatin-specific transcription elongation factor 140 kDa subunit).

41_MOUSE
NC score	0.014858 (rank : 310)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	314	Target Neighborhood Hits	184	Shared Neighborhood Hits	26
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

CP053_HUMAN
NC score	0.014848 (rank : 311)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	314	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTK6	Gene names	C16orf53
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf53.

CD2L1_MOUSE
NC score	0.014648 (rank : 312)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	314	Target Neighborhood Hits	1463	Shared Neighborhood Hits	61
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

NUCL_HUMAN
NC score	0.014610 (rank : 313)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	314	Target Neighborhood Hits	415	Shared Neighborhood Hits	29
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

NOP14_MOUSE
NC score	0.014594 (rank : 314)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	314	Target Neighborhood Hits	324	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PTPRG_MOUSE
NC score	0.014499 (rank : 315)	θ value	0.125558 (rank : 122)
Query Neighborhood Hits	314	Target Neighborhood Hits	260	Shared Neighborhood Hits	20
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CLMN_HUMAN
NC score	0.014391 (rank : 316)	θ value	2.36792 (rank : 198)
Query Neighborhood Hits	314	Target Neighborhood Hits	205	Shared Neighborhood Hits	42
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

FMN1A_MOUSE
NC score	0.014206 (rank : 317)	θ value	4.03905 (rank : 229)
Query Neighborhood Hits	314	Target Neighborhood Hits	423	Shared Neighborhood Hits	30
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

LR37B_HUMAN
NC score	0.014125 (rank : 318)	θ value	0.47712 (rank : 145)
Query Neighborhood Hits	314	Target Neighborhood Hits	392	Shared Neighborhood Hits	18
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

EP400_HUMAN
NC score	0.014107 (rank : 319)	θ value	4.03905 (rank : 225)
Query Neighborhood Hits	314	Target Neighborhood Hits	556	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PTPRG_HUMAN
NC score	0.014041 (rank : 320)	θ value	0.0431538 (rank : 108)
Query Neighborhood Hits	314	Target Neighborhood Hits	231	Shared Neighborhood Hits	16
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CJ026_MOUSE
NC score	0.013911 (rank : 321)	θ value	4.03905 (rank : 223)
Query Neighborhood Hits	314	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGW2, Q3TF48, Q3U3M2, Q6PD43, Q8R0W8	Gene names	D19Wsu162e
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf26 homolog.

K0152_MOUSE
NC score	0.013475 (rank : 322)	θ value	4.03905 (rank : 230)
Query Neighborhood Hits	314	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZQI3, Q8C6C3, Q8CD40, Q8CI91	Gene names	Kiaa0152
Domain Architecture	No domain graphic available
Description	Protein KIAA0152 precursor.

RUSC2_MOUSE
NC score	0.012991 (rank : 323)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	314	Target Neighborhood Hits	305	Shared Neighborhood Hits	28
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

PEG3_MOUSE
NC score	0.012890 (rank : 324)	θ value	0.125558 (rank : 120)
Query Neighborhood Hits	314	Target Neighborhood Hits	1101	Shared Neighborhood Hits	89
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

RPF53_HUMAN
NC score	0.012831 (rank : 325)	θ value	4.03905 (rank : 238)
Query Neighborhood Hits	314	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZS1, Q5VZT3, Q8NBA9, Q96L20	Gene names	PRAF1, PAF53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

FGD5_HUMAN
NC score	0.012771 (rank : 326)	θ value	5.27518 (rank : 250)
Query Neighborhood Hits	314	Target Neighborhood Hits	235	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

PP2CG_HUMAN
NC score	0.012665 (rank : 327)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	314	Target Neighborhood Hits	140	Shared Neighborhood Hits	16
SwissProt Accessions	O15355	Gene names	PPM1G, PPM1C
Domain Architecture
Description	Protein phosphatase 2C isoform gamma (EC 3.1.3.16) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) (Protein phosphatase 1C).

CUTL2_HUMAN
NC score	0.012116 (rank : 328)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	314	Target Neighborhood Hits	906	Shared Neighborhood Hits	48
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

RYR1_HUMAN
NC score	0.011953 (rank : 329)	θ value	4.03905 (rank : 239)
Query Neighborhood Hits	314	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

DDX21_MOUSE
NC score	0.011243 (rank : 330)	θ value	1.06291 (rank : 170)
Query Neighborhood Hits	314	Target Neighborhood Hits	350	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

TF3C1_HUMAN
NC score	0.011119 (rank : 331)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	314	Target Neighborhood Hits	88	Shared Neighborhood Hits	12
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

PRDM2_HUMAN
NC score	0.010936 (rank : 332)	θ value	3.0926 (rank : 215)
Query Neighborhood Hits	314	Target Neighborhood Hits	1135	Shared Neighborhood Hits	53
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

HD_HUMAN
NC score	0.010866 (rank : 333)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	314	Target Neighborhood Hits	165	Shared Neighborhood Hits	14
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

IQEC3_MOUSE
NC score	0.010464 (rank : 334)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	314	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

LRC50_HUMAN
NC score	0.010128 (rank : 335)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	314	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NEP3, Q69YI8, Q69YJ0, Q96LP3	Gene names	LRRC50
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 50.

CD2L1_HUMAN
NC score	0.010078 (rank : 336)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	314	Target Neighborhood Hits	1467	Shared Neighborhood Hits	57
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

MYCL1_MOUSE
NC score	0.009860 (rank : 337)	θ value	3.0926 (rank : 213)
Query Neighborhood Hits	314	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

CHSS3_HUMAN
NC score	0.009679 (rank : 338)	θ value	1.81305 (rank : 187)
Query Neighborhood Hits	314	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

TXLNB_MOUSE
NC score	0.009651 (rank : 339)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	314	Target Neighborhood Hits	640	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

CCD27_MOUSE
NC score	0.009422 (rank : 340)	θ value	3.0926 (rank : 210)
Query Neighborhood Hits	314	Target Neighborhood Hits	461	Shared Neighborhood Hits	18
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

FYCO1_MOUSE
NC score	0.009382 (rank : 341)	θ value	0.47712 (rank : 144)
Query Neighborhood Hits	314	Target Neighborhood Hits	1059	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

FBX31_HUMAN
NC score	0.009251 (rank : 342)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	314	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XUX0, Q96D73, Q9UFV4	Gene names	FBXO31, FBX14, FBX31
Domain Architecture	No domain graphic available
Description	F-box only protein 31.

SAPS3_MOUSE
NC score	0.009153 (rank : 343)	θ value	3.0926 (rank : 216)
Query Neighborhood Hits	314	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q922D4, Q6ZPM9, Q8BTW6, Q9D2X9	Gene names	Saps3, D19Ertd703e, Kiaa1558
Domain Architecture	No domain graphic available
Description	SAPS domain family member 3.

GP152_HUMAN
NC score	0.008922 (rank : 344)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	314	Target Neighborhood Hits	636	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

ABCF1_HUMAN
NC score	0.008832 (rank : 345)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	314	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

STK36_HUMAN
NC score	0.008705 (rank : 346)	θ value	0.47712 (rank : 150)
Query Neighborhood Hits	314	Target Neighborhood Hits	896	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

MBD1_MOUSE
NC score	0.008589 (rank : 347)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	314	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

RBM19_HUMAN
NC score	0.008448 (rank : 348)	θ value	2.36792 (rank : 204)
Query Neighborhood Hits	314	Target Neighborhood Hits	331	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

K0319_MOUSE
NC score	0.008216 (rank : 349)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	314	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

TOPRS_MOUSE
NC score	0.008120 (rank : 350)	θ value	4.03905 (rank : 241)
Query Neighborhood Hits	314	Target Neighborhood Hits	263	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TTBK1_HUMAN
NC score	0.008097 (rank : 351)	θ value	8.99809 (rank : 312)
Query Neighborhood Hits	314	Target Neighborhood Hits	1058	Shared Neighborhood Hits	52
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

NTBP1_HUMAN
NC score	0.007854 (rank : 352)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	314	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

ERCC6_HUMAN
NC score	0.007785 (rank : 353)	θ value	4.03905 (rank : 228)
Query Neighborhood Hits	314	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

EHMT2_MOUSE
NC score	0.007691 (rank : 354)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	314	Target Neighborhood Hits	750	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ERC2_MOUSE
NC score	0.007519 (rank : 355)	θ value	4.03905 (rank : 227)
Query Neighborhood Hits	314	Target Neighborhood Hits	1166	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

JHD3B_HUMAN
NC score	0.007483 (rank : 356)	θ value	3.0926 (rank : 212)
Query Neighborhood Hits	314	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

ERC2_HUMAN
NC score	0.007223 (rank : 357)	θ value	4.03905 (rank : 226)
Query Neighborhood Hits	314	Target Neighborhood Hits	1156	Shared Neighborhood Hits	37
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

GOGA1_HUMAN
NC score	0.007076 (rank : 358)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	314	Target Neighborhood Hits	1222	Shared Neighborhood Hits	48
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

TTF2_HUMAN
NC score	0.006453 (rank : 359)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	314	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

CAC1F_HUMAN
NC score	0.006358 (rank : 360)	θ value	1.06291 (rank : 168)
Query Neighborhood Hits	314	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CXA8_HUMAN
NC score	0.005956 (rank : 361)	θ value	1.81305 (rank : 190)
Query Neighborhood Hits	314	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

TBX3_MOUSE
NC score	0.005931 (rank : 362)	θ value	1.81305 (rank : 195)
Query Neighborhood Hits	314	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	P70324, Q60708, Q8BWH7	Gene names	Tbx3
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX3 (T-box protein 3).

CAC1H_MOUSE
NC score	0.005568 (rank : 363)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	314	Target Neighborhood Hits	230	Shared Neighborhood Hits	15
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CEP72_MOUSE
NC score	0.005528 (rank : 364)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	314	Target Neighborhood Hits	381	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

EPC2_MOUSE
NC score	0.005491 (rank : 365)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	314	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

BRE1A_HUMAN
NC score	0.004714 (rank : 366)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	314	Target Neighborhood Hits	1071	Shared Neighborhood Hits	39
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CXA8_MOUSE
NC score	0.004575 (rank : 367)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	314	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P28236	Gene names	Gja8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

B3A2_HUMAN
NC score	0.004096 (rank : 368)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	314	Target Neighborhood Hits	57	Shared Neighborhood Hits	8
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

HTF4_HUMAN
NC score	0.003937 (rank : 369)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	314	Target Neighborhood Hits	152	Shared Neighborhood Hits	8
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

ZHX3_MOUSE
NC score	0.003792 (rank : 370)	θ value	6.88961 (rank : 289)
Query Neighborhood Hits	314	Target Neighborhood Hits	321	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

GSPT1_MOUSE
NC score	0.003454 (rank : 371)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	314	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R050, O88179	Gene names	Gspt1
Domain Architecture
Description	G1 to S phase transition protein 1 homolog.

TNNT3_MOUSE
NC score	0.002995 (rank : 372)	θ value	8.99809 (rank : 311)
Query Neighborhood Hits	314	Target Neighborhood Hits	317	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QZ47, O35575, O35576, O35577, O35578, O35579, O35580, O35581, O35582, O35583, O35584, O35585, P97456, Q99L89, Q9QZ46	Gene names	Tnnt3
Domain Architecture	No domain graphic available
Description	Troponin T, fast skeletal muscle (TnTf) (Fast skeletal muscle troponin T) (fTnT).

PLEC1_HUMAN
NC score	0.002969 (rank : 373)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	314	Target Neighborhood Hits	1326	Shared Neighborhood Hits	42
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PRS10_HUMAN
NC score	0.002968 (rank : 374)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.002968 (rank : 375)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	314	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

ATBF1_HUMAN
NC score	0.002348 (rank : 376)	θ value	3.0926 (rank : 209)
Query Neighborhood Hits	314	Target Neighborhood Hits	1547	Shared Neighborhood Hits	53
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ELK1_MOUSE
NC score	0.002081 (rank : 377)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	314	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

WDR43_HUMAN
NC score	0.002066 (rank : 378)	θ value	8.99809 (rank : 313)
Query Neighborhood Hits	314	Target Neighborhood Hits	269	Shared Neighborhood Hits	8
SwissProt Accessions	Q15061, Q15395, Q92577	Gene names	WDR43, KIAA0007
Domain Architecture	No domain graphic available
Description	WD repeat protein 43.

FOG1_HUMAN
NC score	0.001886 (rank : 379)	θ value	3.0926 (rank : 211)
Query Neighborhood Hits	314	Target Neighborhood Hits	981	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

ATS1_MOUSE
NC score	-0.000012 (rank : 380)	θ value	4.03905 (rank : 219)
Query Neighborhood Hits	314	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

PEG3_HUMAN
NC score	-0.000389 (rank : 381)	θ value	1.06291 (rank : 174)
Query Neighborhood Hits	314	Target Neighborhood Hits	800	Shared Neighborhood Hits	30
SwissProt Accessions	Q9GZU2, P78418, Q5H9P9, Q7Z7H7, Q8TF75, Q9GZY2	Gene names	PEG3, KIAA0287
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein.

TCF8_MOUSE
NC score	-0.002451 (rank : 382)	θ value	8.99809 (rank : 310)
Query Neighborhood Hits	314	Target Neighborhood Hits	1067	Shared Neighborhood Hits	48
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

ZBTB9_MOUSE
NC score	-0.003340 (rank : 383)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	314	Target Neighborhood Hits	780	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

ZBT17_HUMAN
NC score	-0.004175 (rank : 384)	θ value	0.47712 (rank : 151)
Query Neighborhood Hits	314	Target Neighborhood Hits	925	Shared Neighborhood Hits	25
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

CTCF_HUMAN
NC score	-0.005599 (rank : 385)	θ value	5.27518 (rank : 249)
Query Neighborhood Hits	314	Target Neighborhood Hits	764	Shared Neighborhood Hits	20
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

BCL6_MOUSE
NC score	-0.005662 (rank : 386)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	314	Target Neighborhood Hits	913	Shared Neighborhood Hits	28
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

ZBT20_HUMAN
NC score	-0.005748 (rank : 387)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	314	Target Neighborhood Hits	835	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).