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Network neighborhood for query Sequence : CHSS3_HUMAN

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CHSS3_HUMAN
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHSS1_HUMAN
θ value	0 (rank : 1)	NC score	0.985423 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
θ value	0 (rank : 2)	NC score	0.984780 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS3_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CGAT1_HUMAN
θ value	4.11246e-53 (rank : 4)	NC score	0.818296 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT1_MOUSE
θ value	5.37103e-53 (rank : 5)	NC score	0.820093 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT2_MOUSE
θ value	1.23823e-49 (rank : 6)	NC score	0.818030 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_HUMAN
θ value	2.75849e-49 (rank : 7)	NC score	0.818138 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CHGUT_HUMAN
θ value	1.28434e-38 (rank : 8)	NC score	0.718281 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

CHSS2_MOUSE
θ value	4.13158e-37 (rank : 9)	NC score	0.723099 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHSS2_HUMAN
θ value	3.27365e-34 (rank : 10)	NC score	0.719303 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

B4GN3_HUMAN
θ value	6.64225e-11 (rank : 11)	NC score	0.460866 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN3_MOUSE
θ value	1.25267e-09 (rank : 12)	NC score	0.466130 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN4_MOUSE
θ value	2.13673e-09 (rank : 13)	NC score	0.470132 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	27
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN4_HUMAN
θ value	2.79066e-09 (rank : 14)	NC score	0.471310 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B3GLT_MOUSE
θ value	4.0297e-08 (rank : 15)	NC score	0.357285 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B3GLT_HUMAN
θ value	3.41135e-07 (rank : 16)	NC score	0.342602 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

RFNG_MOUSE
θ value	4.1701e-05 (rank : 17)	NC score	0.245429 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_MOUSE
θ value	0.000121331 (rank : 18)	NC score	0.237310 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_HUMAN
θ value	0.00102713 (rank : 19)	NC score	0.223964 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

MFNG_MOUSE
θ value	0.00298849 (rank : 20)	NC score	0.182262 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	O09008	Gene names	Mfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GT2_HUMAN
θ value	0.00869519 (rank : 21)	NC score	0.168660 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	O60909, O60511, Q5T4X5, Q5T4Y5, Q9BUP6, Q9NSY7	Gene names	B4GALT2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT2_MOUSE
θ value	0.00869519 (rank : 22)	NC score	0.167682 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2Y2, Q3TMP2	Gene names	B4galt2
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SF3B1_HUMAN
θ value	0.0431538 (rank : 23)	NC score	0.061669 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0431538 (rank : 24)	NC score	0.061674 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

B4GT1_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.130862 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT1_MOUSE
θ value	0.0563607 (rank : 26)	NC score	0.142877 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

RFNG_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.219005 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

SEPT9_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.020043 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	706	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CO9A1_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.026919 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	477	Shared Neighborhood Hits	21
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

B4GT4_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.120792 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJ04, Q8BR54, Q9QY12	Gene names	B4galt4
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 4 (EC 2.4.1.-) (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 4) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

CO4A3_HUMAN
θ value	0.163984 (rank : 31)	NC score	0.024920 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	421	Shared Neighborhood Hits	20
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

SRRM1_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.034960 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	966	Shared Neighborhood Hits	25
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ETV3_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.017563 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

BSN_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.024621 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1A_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.016399 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	267	Shared Neighborhood Hits	11
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

IF4B_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.040082 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CO9A1_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.025782 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

GLT12_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.020617 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IXK2, Q5TCF7, Q8NG54, Q96CT9, Q9H771	Gene names	GALNT12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

MFNG_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.161713 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O00587, O43730	Gene names	MFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B3GL1_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.052087 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	O75752, Q3Y531, Q6IAI5, Q8NFM8, Q9HA06	Gene names	B3GALNT1, B3GALT3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

CU087_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.057337 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P59051	Gene names	C21orf87
Domain Architecture	No domain graphic available
Description	Protein C21orf87.

IF4B_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.036426 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KCD12_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.024572 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

CAC1G_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.018503 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	587	Shared Neighborhood Hits	12
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

B4GT4_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.116314 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	O60513, Q68D68, Q9BSW3, Q9C078	Gene names	B4GALT4
Domain Architecture
Description	Beta-1,4-galactosyltransferase 4 (EC 2.4.1.-) (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 4) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

GDPD5_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.025925 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q640M6, Q8R0T5, Q8R3N5	Gene names	Gdpd5, Gde2
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2).

GLT12_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.020152 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

RGS3_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.014320 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

KCD12_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.022489 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

TCGAP_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.014739 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	872	Shared Neighborhood Hits	21
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ZN212_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.000988 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	699	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UDV6, Q13396, Q8N664	Gene names	ZNF212, ZNFC150
Domain Architecture	No domain graphic available
Description	Zinc finger protein 212 (Zinc finger protein C2H2-150).

B4GT7_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.091369 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBV7, Q9UHN2	Gene names	B4GALT7, XGALT1
Domain Architecture
Description	Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-) (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 7) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 7) [Includes: Xylosylprotein 4-beta- galactosyltransferase (EC 2.4.1.133) (UDP-galactose:beta-xylose beta- 1,4-galactosyltransferase) (Xylosylprotein beta-1,4- galactosyltransferase) (XGPT) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (XGalT-1)].

B4GT7_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.093599 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R087, Q7TNU3	Gene names	B4galt7, Xgalt1
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-) (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 7) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 7) [Includes: Xylosylprotein 4-beta- galactosyltransferase (EC 2.4.1.133) (UDP-galactose:beta-xylose beta- 1,4-galactosyltransferase) (Xylosylprotein beta-1,4- galactosyltransferase) (XGPT) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (XGalT-1)].

GDPD5_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.024486 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTR4, Q49AQ5, Q6UX76, Q7Z4S0, Q8N781, Q8NCB7, Q8TB77	Gene names	GDPD5, GDE2
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2).

OGFR_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.019754 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	1582	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SNPC4_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.021502 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SYTL1_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.009679 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	314	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

B3A4_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.009222 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

COBA1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.022537 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.022755 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	487	Shared Neighborhood Hits	27
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

MKL1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.016019 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	667	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SAPS1_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.018029 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	704	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

ZAR1_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.024059 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

B4GT3_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.091715 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT3_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.092544 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SEN34_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.020336 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

SNX19_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.020179 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

SON_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.015932 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	1568	Shared Neighborhood Hits	28
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TNFL6_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.018034 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P48023, Q9BZP9	Gene names	FASLG, APT1LG1, FASL, TNFSF6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) (Apoptosis antigen ligand) (APTL) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

ZN133_HUMAN
θ value	3.0926 (rank : 70)	NC score	-0.001986 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	P52736, Q9BUV2, Q9H443	Gene names	ZNF133
Domain Architecture
Description	Zinc finger protein 133.

B4GT6_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.088635 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBX8, O60514	Gene names	B4GALT6
Domain Architecture
Description	Beta-1,4-galactosyltransferase 6 (EC 2.4.1.-) (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 6) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 6) [Includes: Lactosylceramide synthase (EC 2.4.1.-) (LacCer synthase) (UDP-Gal:glucosylceramide beta-1,4- galactosyltransferase)].

B4GT6_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.088404 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVK5	Gene names	B4galt6
Domain Architecture
Description	Beta-1,4-galactosyltransferase 6 (EC 2.4.1.-) (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 6) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 6) [Includes: Lactosylceramide synthase (EC 2.4.1.-) (LacCer synthase) (UDP-Gal:glucosylceramide beta-1,4- galactosyltransferase)].

CASL_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.009439 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

CTDP1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.023145 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	416	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

GALT4_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.017550 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4A0, O00208	Gene names	GALNT4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).

GALT4_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.017876 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	O08832, Q3U681	Gene names	Galnt4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).

SYNE2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.004631 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	1323	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

B3GL1_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.033650 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q920V1, O54906, Q91V72, Q920V0, Q9CTE5	Gene names	b3galnt1, B3galt3, B3gt3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

B3GT1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.020029 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5Z6	Gene names	B3GALT1
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,3-GalTase 1) (Beta3GalT1) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3- galactosyltransferase 1).

B3GT1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.020029 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	O54904, Q91V52	Gene names	B3galt1
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,3-GalTase 1) (Beta3GalT1) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3- galactosyltransferase 1) (UDP-Gal:betaGlcNAc beta 1,3- galactosyltransferase-I).

CAC1H_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.015375 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

ANGL6_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.003561 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

CO1A1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.022505 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO5A2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.017582 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	760	Shared Neighborhood Hits	22
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CSTF2_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.007178 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

GALT6_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.018292 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCL4, Q8IYH4, Q9H6G2, Q9UIV5	Gene names	GALNT6
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6).

RPKL1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.000156 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	704	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

ZN185_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.014578 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

ZN282_HUMAN
θ value	6.88961 (rank : 89)	NC score	-0.001543 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	796	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

B3GN1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.016171 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY97, Q9NQQ9, Q9NQR0, Q9NUT9	Gene names	B3GNT1, B3GALT7
Domain Architecture
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (EC 2.4.1.-) (Beta3Gn-T1) (BGnT-1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (b3Gal-T7) (UDP-galactose:beta-N- acetylglucosamine beta-1,3-galactosyltransferase 7) (UDP-Gal:beta- GlcNAc beta-1,3-galactosyltransferase 7) (Beta-3-Gx-T7).

CENPQ_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.009894 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

CO2A1_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.021481 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	486	Shared Neighborhood Hits	28
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO7A1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.013967 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	807	Shared Neighborhood Hits	24
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CS007_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.013304 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

JPH2_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.012145 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	639	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

RP3A_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.006946 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	510	Shared Neighborhood Hits	23
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TMUB1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.011096 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVT8	Gene names	TMUB1, C7orf21
Domain Architecture
Description	Transmembrane and ubiquitin-like domain-containing protein 1 (Ubiquitin-like protein SB144).

B4GT5_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.083258 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	O43286, Q2M394, Q9UJQ8	Gene names	B4GALT5
Domain Architecture
Description	Beta-1,4-galactosyltransferase 5 (EC 2.4.1.-) (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 5) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 5) (Beta-1,4-GalT II).

B4GT5_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.083652 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMK0	Gene names	B4galt5, Bgt-5
Domain Architecture
Description	Beta-1,4-galactosyltransferase 5 (EC 2.4.1.-) (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 5) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 5) (Beta-1,4-GalT II).

Hits sorted by NC score

CHSS3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CHSS1_HUMAN
NC score	0.985423 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q86X52, Q6UX38, Q7LFU5, Q9Y2J5	Gene names	CHSY1, CHSY, CSS1, KIAA0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1) (Chondroitin sulfate synthase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CHSS1_MOUSE
NC score	0.984780 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZQ11	Gene names	Chsy1, Kiaa0990
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 1 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase) (Chondroitin sulfate synthase 1) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II).

CGAT1_MOUSE
NC score	0.820093 (rank : 4)	θ value	5.37103e-53 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJQ9, Q3UZX6, Q8BWV9, Q8BZU7, Q8C195, Q8R0M6	Gene names	Galnact1, Chgn
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT1_HUMAN
NC score	0.818296 (rank : 5)	θ value	4.11246e-53 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDX6, Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9	Gene names	GALNACT1, CHGN
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.174) (beta4GalNAcT-1).

CGAT2_HUMAN
NC score	0.818138 (rank : 6)	θ value	2.75849e-49 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N6G5, Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6	Gene names	GALNACT2, CHGN2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CGAT2_MOUSE
NC score	0.818030 (rank : 7)	θ value	1.23823e-49 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

CHSS2_MOUSE
NC score	0.723099 (rank : 8)	θ value	4.13158e-37 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IQX7	Gene names	Css2, D1Bwg1363e
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase).

CHSS2_HUMAN
NC score	0.719303 (rank : 9)	θ value	3.27365e-34 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZ52, Q6UXD6, Q7L4G1, Q9H0F8, Q9H618	Gene names	CSS2, CHPF
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 2 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl- proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase) (Chondroitin-polymerizing factor).

CHGUT_HUMAN
NC score	0.718281 (rank : 10)	θ value	1.28434e-38 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2E5, Q6P2I4, Q6UXD2	Gene names	CSGLCAT, KIAA1402
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) (Chondroitin glucuronyltransferase II) (CSGlcA-T).

B4GN4_HUMAN
NC score	0.471310 (rank : 11)	θ value	2.79066e-09 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN4_MOUSE
NC score	0.470132 (rank : 12)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	27
SwissProt Accessions	Q766D5, Q8CHV2	Gene names	B4galnt4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

B4GN3_MOUSE
NC score	0.466130 (rank : 13)	θ value	1.25267e-09 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B4GN3_HUMAN
NC score	0.460866 (rank : 14)	θ value	6.64225e-11 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L9W6, Q6ZNC1, Q8N7T6	Gene names	B4GALNT3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

B3GLT_MOUSE
NC score	0.357285 (rank : 15)	θ value	4.0297e-08 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHT6, Q0PCR7, Q149S5	Gene names	B3galtl, Gm1057
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

B3GLT_HUMAN
NC score	0.342602 (rank : 16)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q6Y288, Q5W0H2, Q6NUI3	Gene names	B3GALTL, B3GTL
Domain Architecture	No domain graphic available
Description	Beta-1,3-glucosyltransferase (EC 2.4.1.-) (Beta3Glc-T) (Beta-3- glycosyltransferase-like).

RFNG_MOUSE
NC score	0.245429 (rank : 17)	θ value	4.1701e-05 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O09009	Gene names	Rfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_MOUSE
NC score	0.237310 (rank : 18)	θ value	0.000121331 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O09010, Q3U659, Q8K3F1, Q9DC10	Gene names	Lfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

LFNG_HUMAN
NC score	0.223964 (rank : 19)	θ value	0.00102713 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NES3, O00589, Q96C39, Q9UJW5	Gene names	LFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

RFNG_HUMAN
NC score	0.219005 (rank : 20)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y644, O00588	Gene names	RFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

MFNG_MOUSE
NC score	0.182262 (rank : 21)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	O09008	Gene names	Mfng
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GT2_HUMAN
NC score	0.168660 (rank : 22)	θ value	0.00869519 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	O60909, O60511, Q5T4X5, Q5T4Y5, Q9BUP6, Q9NSY7	Gene names	B4GALT2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT2_MOUSE
NC score	0.167682 (rank : 23)	θ value	0.00869519 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z2Y2, Q3TMP2	Gene names	B4galt2
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 2 (EC 2.4.1.-) (Beta-1,4-GalTase 2) (Beta4Gal-T2) (b4Gal-T2) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 2) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 2) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

MFNG_HUMAN
NC score	0.161713 (rank : 24)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	O00587, O43730	Gene names	MFNG
Domain Architecture
Description	Beta-1,3-N-acetylglucosaminyltransferase manic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase).

B4GT1_MOUSE
NC score	0.142877 (rank : 25)	θ value	0.0563607 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT1_HUMAN
NC score	0.130862 (rank : 26)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT4_MOUSE
NC score	0.120792 (rank : 27)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JJ04, Q8BR54, Q9QY12	Gene names	B4galt4
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 4 (EC 2.4.1.-) (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 4) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT4_HUMAN
NC score	0.116314 (rank : 28)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	O60513, Q68D68, Q9BSW3, Q9C078	Gene names	B4GALT4
Domain Architecture
Description	Beta-1,4-galactosyltransferase 4 (EC 2.4.1.-) (Beta-1,4-GalTase 4) (Beta4Gal-T4) (b4Gal-T4) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 4) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 4) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT7_MOUSE
NC score	0.093599 (rank : 29)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R087, Q7TNU3	Gene names	B4galt7, Xgalt1
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-) (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 7) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 7) [Includes: Xylosylprotein 4-beta- galactosyltransferase (EC 2.4.1.133) (UDP-galactose:beta-xylose beta- 1,4-galactosyltransferase) (Xylosylprotein beta-1,4- galactosyltransferase) (XGPT) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (XGalT-1)].

B4GT3_MOUSE
NC score	0.092544 (rank : 30)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q91YY2, Q9QY13	Gene names	B4galt3
Domain Architecture	No domain graphic available
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT3_HUMAN
NC score	0.091715 (rank : 31)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	O60512, O60910, Q9BPZ4, Q9H8T2	Gene names	B4GALT3
Domain Architecture
Description	Beta-1,4-galactosyltransferase 3 (EC 2.4.1.-) (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 3) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N- acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

B4GT7_HUMAN
NC score	0.091369 (rank : 32)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBV7, Q9UHN2	Gene names	B4GALT7, XGALT1
Domain Architecture
Description	Beta-1,4-galactosyltransferase 7 (EC 2.4.1.-) (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 7) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 7) [Includes: Xylosylprotein 4-beta- galactosyltransferase (EC 2.4.1.133) (UDP-galactose:beta-xylose beta- 1,4-galactosyltransferase) (Xylosylprotein beta-1,4- galactosyltransferase) (XGPT) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (XGalT-1)].

B4GT6_HUMAN
NC score	0.088635 (rank : 33)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBX8, O60514	Gene names	B4GALT6
Domain Architecture
Description	Beta-1,4-galactosyltransferase 6 (EC 2.4.1.-) (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 6) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 6) [Includes: Lactosylceramide synthase (EC 2.4.1.-) (LacCer synthase) (UDP-Gal:glucosylceramide beta-1,4- galactosyltransferase)].

B4GT6_MOUSE
NC score	0.088404 (rank : 34)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVK5	Gene names	B4galt6
Domain Architecture
Description	Beta-1,4-galactosyltransferase 6 (EC 2.4.1.-) (Beta-1,4-GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 6) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 6) [Includes: Lactosylceramide synthase (EC 2.4.1.-) (LacCer synthase) (UDP-Gal:glucosylceramide beta-1,4- galactosyltransferase)].

B4GT5_MOUSE
NC score	0.083652 (rank : 35)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMK0	Gene names	B4galt5, Bgt-5
Domain Architecture
Description	Beta-1,4-galactosyltransferase 5 (EC 2.4.1.-) (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 5) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 5) (Beta-1,4-GalT II).

B4GT5_HUMAN
NC score	0.083258 (rank : 36)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	23	Shared Neighborhood Hits	17
SwissProt Accessions	O43286, Q2M394, Q9UJQ8	Gene names	B4GALT5
Domain Architecture
Description	Beta-1,4-galactosyltransferase 5 (EC 2.4.1.-) (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 5) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 5) (Beta-1,4-GalT II).

SF3B1_MOUSE
NC score	0.061674 (rank : 37)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.061669 (rank : 38)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CU087_HUMAN
NC score	0.057337 (rank : 39)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P59051	Gene names	C21orf87
Domain Architecture	No domain graphic available
Description	Protein C21orf87.

B3GL1_HUMAN
NC score	0.052087 (rank : 40)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	O75752, Q3Y531, Q6IAI5, Q8NFM8, Q9HA06	Gene names	B3GALNT1, B3GALT3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

IF4B_MOUSE
NC score	0.040082 (rank : 41)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_HUMAN
NC score	0.036426 (rank : 42)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	417	Shared Neighborhood Hits	11
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SRRM1_MOUSE
NC score	0.034960 (rank : 43)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	966	Shared Neighborhood Hits	25
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

B3GL1_MOUSE
NC score	0.033650 (rank : 44)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q920V1, O54906, Q91V72, Q920V0, Q9CTE5	Gene names	b3galnt1, B3galt3, B3gt3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

CO9A1_MOUSE
NC score	0.026919 (rank : 45)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	477	Shared Neighborhood Hits	21
SwissProt Accessions	Q05722, Q61269, Q61270, Q61433, Q61940	Gene names	Col9a1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

GDPD5_MOUSE
NC score	0.025925 (rank : 46)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q640M6, Q8R0T5, Q8R3N5	Gene names	Gdpd5, Gde2
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2).

CO9A1_HUMAN
NC score	0.025782 (rank : 47)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	420	Shared Neighborhood Hits	19
SwissProt Accessions	P20849, Q13699, Q13700, Q5TF52, Q6P467, Q96BM8, Q99225, Q9H151, Q9H152, Q9Y6P2, Q9Y6P3	Gene names	COL9A1
Domain Architecture
Description	Collagen alpha-1(IX) chain precursor.

CO4A3_HUMAN
NC score	0.024920 (rank : 48)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	421	Shared Neighborhood Hits	20
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

BSN_MOUSE
NC score	0.024621 (rank : 49)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCD12_HUMAN
NC score	0.024572 (rank : 50)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

GDPD5_HUMAN
NC score	0.024486 (rank : 51)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WTR4, Q49AQ5, Q6UX76, Q7Z4S0, Q8N781, Q8NCB7, Q8TB77	Gene names	GDPD5, GDE2
Domain Architecture	No domain graphic available
Description	Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2).

ZAR1_MOUSE
NC score	0.024059 (rank : 52)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

CTDP1_HUMAN
NC score	0.023145 (rank : 53)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	416	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

COBA1_MOUSE
NC score	0.022755 (rank : 54)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	487	Shared Neighborhood Hits	27
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_HUMAN
NC score	0.022537 (rank : 55)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CO1A1_HUMAN
NC score	0.022505 (rank : 56)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

KCD12_MOUSE
NC score	0.022489 (rank : 57)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

SNPC4_HUMAN
NC score	0.021502 (rank : 58)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CO2A1_HUMAN
NC score	0.021481 (rank : 59)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	486	Shared Neighborhood Hits	28
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

GLT12_HUMAN
NC score	0.020617 (rank : 60)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IXK2, Q5TCF7, Q8NG54, Q96CT9, Q9H771	Gene names	GALNT12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

SEN34_HUMAN
NC score	0.020336 (rank : 61)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

SNX19_HUMAN
NC score	0.020179 (rank : 62)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q92543	Gene names	SNX19, KIAA0254
Domain Architecture
Description	Sorting nexin-19.

GLT12_MOUSE
NC score	0.020152 (rank : 63)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

SEPT9_HUMAN
NC score	0.020043 (rank : 64)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	706	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

B3GT1_HUMAN
NC score	0.020029 (rank : 65)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5Z6	Gene names	B3GALT1
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,3-GalTase 1) (Beta3GalT1) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3- galactosyltransferase 1).

B3GT1_MOUSE
NC score	0.020029 (rank : 66)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	O54904, Q91V52	Gene names	B3galt1
Domain Architecture	No domain graphic available
Description	Beta-1,3-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,3-GalTase 1) (Beta3GalT1) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3- galactosyltransferase 1) (UDP-Gal:betaGlcNAc beta 1,3- galactosyltransferase-I).

OGFR_HUMAN
NC score	0.019754 (rank : 67)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	1582	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CAC1G_HUMAN
NC score	0.018503 (rank : 68)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	587	Shared Neighborhood Hits	12
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GALT6_HUMAN
NC score	0.018292 (rank : 69)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCL4, Q8IYH4, Q9H6G2, Q9UIV5	Gene names	GALNT6
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6).

TNFL6_HUMAN
NC score	0.018034 (rank : 70)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	P48023, Q9BZP9	Gene names	FASLG, APT1LG1, FASL, TNFSF6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) (Apoptosis antigen ligand) (APTL) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

SAPS1_HUMAN
NC score	0.018029 (rank : 71)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	704	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

GALT4_MOUSE
NC score	0.017876 (rank : 72)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	O08832, Q3U681	Gene names	Galnt4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).

CO5A2_HUMAN
NC score	0.017582 (rank : 73)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	760	Shared Neighborhood Hits	22
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ETV3_HUMAN
NC score	0.017563 (rank : 74)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	312	Shared Neighborhood Hits	7
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

GALT4_HUMAN
NC score	0.017550 (rank : 75)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N4A0, O00208	Gene names	GALNT4
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4).

CAC1A_MOUSE
NC score	0.016399 (rank : 76)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	267	Shared Neighborhood Hits	11
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

B3GN1_HUMAN
NC score	0.016171 (rank : 77)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NY97, Q9NQQ9, Q9NQR0, Q9NUT9	Gene names	B3GNT1, B3GALT7
Domain Architecture
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (EC 2.4.1.-) (Beta3Gn-T1) (BGnT-1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (b3Gal-T7) (UDP-galactose:beta-N- acetylglucosamine beta-1,3-galactosyltransferase 7) (UDP-Gal:beta- GlcNAc beta-1,3-galactosyltransferase 7) (Beta-3-Gx-T7).

MKL1_MOUSE
NC score	0.016019 (rank : 78)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	667	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SON_HUMAN
NC score	0.015932 (rank : 79)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	1568	Shared Neighborhood Hits	28
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CAC1H_HUMAN
NC score	0.015375 (rank : 80)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

TCGAP_HUMAN
NC score	0.014739 (rank : 81)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	872	Shared Neighborhood Hits	21
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

ZN185_HUMAN
NC score	0.014578 (rank : 82)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

RGS3_MOUSE
NC score	0.014320 (rank : 83)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	1621	Shared Neighborhood Hits	34
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CO7A1_HUMAN
NC score	0.013967 (rank : 84)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	807	Shared Neighborhood Hits	24
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CS007_HUMAN
NC score	0.013304 (rank : 85)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

JPH2_HUMAN
NC score	0.012145 (rank : 86)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	639	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

TMUB1_HUMAN
NC score	0.011096 (rank : 87)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BVT8	Gene names	TMUB1, C7orf21
Domain Architecture
Description	Transmembrane and ubiquitin-like domain-containing protein 1 (Ubiquitin-like protein SB144).

CENPQ_MOUSE
NC score	0.009894 (rank : 88)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPQ5, Q8C2G4, Q8VEF8, Q9CX70	Gene names	Cenpq
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

SYTL1_MOUSE
NC score	0.009679 (rank : 89)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	314	Shared Neighborhood Hits	5
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

CASL_MOUSE
NC score	0.009439 (rank : 90)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	225	Shared Neighborhood Hits	4
SwissProt Accessions	O35177, Q8BJL8, Q8BK90, Q8BL52, Q8BM94, Q8BMI9, Q99KE7	Gene names	Nedd9, Casl
Domain Architecture
Description	Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor cell expressed developmentally down-regulated protein 9).

B3A4_HUMAN
NC score	0.009222 (rank : 91)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

CSTF2_MOUSE
NC score	0.007178 (rank : 92)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	255	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

RP3A_MOUSE
NC score	0.006946 (rank : 93)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	510	Shared Neighborhood Hits	23
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYNE2_HUMAN
NC score	0.004631 (rank : 94)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	1323	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ANGL6_HUMAN
NC score	0.003561 (rank : 95)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

ZN212_HUMAN
NC score	0.000988 (rank : 96)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	699	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UDV6, Q13396, Q8N664	Gene names	ZNF212, ZNFC150
Domain Architecture	No domain graphic available
Description	Zinc finger protein 212 (Zinc finger protein C2H2-150).

RPKL1_MOUSE
NC score	0.000156 (rank : 97)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	704	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

ZN282_HUMAN
NC score	-0.001543 (rank : 98)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	796	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UDV7, O43691, Q6DKK0	Gene names	ZNF282, HUB1
Domain Architecture
Description	Zinc finger protein 282 (HTLV-I U5RE-binding protein 1) (HUB-1).

ZN133_HUMAN
NC score	-0.001986 (rank : 99)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	784	Shared Neighborhood Hits	6
SwissProt Accessions	P52736, Q9BUV2, Q9H443	Gene names	ZNF133
Domain Architecture
Description	Zinc finger protein 133.