Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ERCC6_HUMAN

For an explanation of this page, click here

ERCC6_HUMAN
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERCC6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	247	Target Neighborhood Hits	247	Shared Neighborhood Hits	247
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

BTAF1_HUMAN
θ value	4.36332e-79 (rank : 2)	NC score	0.944390 (rank : 6)
Query Neighborhood Hits	247	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMCA5_HUMAN
θ value	9.0981e-77 (rank : 3)	NC score	0.942124 (rank : 8)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	9.0981e-77 (rank : 4)	NC score	0.942190 (rank : 7)
Query Neighborhood Hits	247	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA1_MOUSE
θ value	1.45253e-74 (rank : 5)	NC score	0.939042 (rank : 10)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

RAD54_HUMAN
θ value	3.23591e-74 (rank : 6)	NC score	0.946990 (rank : 2)
Query Neighborhood Hits	247	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RA54B_HUMAN
θ value	1.60597e-73 (rank : 7)	NC score	0.946502 (rank : 3)
Query Neighborhood Hits	247	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

SMCA1_HUMAN
θ value	6.10265e-73 (rank : 8)	NC score	0.940883 (rank : 9)
Query Neighborhood Hits	247	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

RAD54_MOUSE
θ value	1.35953e-72 (rank : 9)	NC score	0.946116 (rank : 4)
Query Neighborhood Hits	247	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RA54B_MOUSE
θ value	1.15091e-71 (rank : 10)	NC score	0.944502 (rank : 5)
Query Neighborhood Hits	247	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD2_HUMAN
θ value	1.40689e-69 (rank : 11)	NC score	0.922285 (rank : 13)
Query Neighborhood Hits	247	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD5_HUMAN
θ value	4.09345e-69 (rank : 12)	NC score	0.854208 (rank : 27)
Query Neighborhood Hits	247	Target Neighborhood Hits	349	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	1.19101e-68 (rank : 13)	NC score	0.856737 (rank : 25)
Query Neighborhood Hits	247	Target Neighborhood Hits	397	Shared Neighborhood Hits	58
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD1_HUMAN
θ value	3.4653e-68 (rank : 14)	NC score	0.918132 (rank : 16)
Query Neighborhood Hits	247	Target Neighborhood Hits	337	Shared Neighborhood Hits	74
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMCA2_HUMAN
θ value	4.52582e-68 (rank : 15)	NC score	0.894446 (rank : 20)
Query Neighborhood Hits	247	Target Neighborhood Hits	503	Shared Neighborhood Hits	71
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

CHD1_MOUSE
θ value	1.71981e-67 (rank : 16)	NC score	0.919437 (rank : 14)
Query Neighborhood Hits	247	Target Neighborhood Hits	266	Shared Neighborhood Hits	64
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD4_HUMAN
θ value	2.93355e-67 (rank : 17)	NC score	0.855397 (rank : 26)
Query Neighborhood Hits	247	Target Neighborhood Hits	365	Shared Neighborhood Hits	58
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	2.93355e-67 (rank : 18)	NC score	0.852791 (rank : 28)
Query Neighborhood Hits	247	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMCA4_HUMAN
θ value	6.53529e-67 (rank : 19)	NC score	0.883113 (rank : 23)
Query Neighborhood Hits	247	Target Neighborhood Hits	597	Shared Neighborhood Hits	78
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD6_HUMAN
θ value	7.2256e-66 (rank : 20)	NC score	0.915697 (rank : 17)
Query Neighborhood Hits	247	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_MOUSE
θ value	1.6097e-65 (rank : 21)	NC score	0.907487 (rank : 19)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
θ value	7.98882e-65 (rank : 22)	NC score	0.910853 (rank : 18)
Query Neighborhood Hits	247	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

SMRCD_HUMAN
θ value	2.32439e-64 (rank : 23)	NC score	0.938797 (rank : 11)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	1.50663e-63 (rank : 24)	NC score	0.938587 (rank : 12)
Query Neighborhood Hits	247	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD8_HUMAN
θ value	4.38363e-63 (rank : 25)	NC score	0.919073 (rank : 15)
Query Neighborhood Hits	247	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

INOC1_HUMAN
θ value	5.96599e-36 (rank : 26)	NC score	0.890407 (rank : 22)
Query Neighborhood Hits	247	Target Neighborhood Hits	181	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	7.79185e-36 (rank : 27)	NC score	0.890484 (rank : 21)
Query Neighborhood Hits	247	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

TTF2_HUMAN
θ value	1.32909e-35 (rank : 28)	NC score	0.859580 (rank : 24)
Query Neighborhood Hits	247	Target Neighborhood Hits	98	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

ATRX_HUMAN
θ value	1.37539e-32 (rank : 29)	NC score	0.717666 (rank : 37)
Query Neighborhood Hits	247	Target Neighborhood Hits	842	Shared Neighborhood Hits	130
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	5.22648e-32 (rank : 30)	NC score	0.733193 (rank : 34)
Query Neighborhood Hits	247	Target Neighborhood Hits	682	Shared Neighborhood Hits	117
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

EP400_HUMAN
θ value	1.2049e-28 (rank : 31)	NC score	0.803473 (rank : 32)
Query Neighborhood Hits	247	Target Neighborhood Hits	556	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	2.68423e-28 (rank : 32)	NC score	0.796193 (rank : 33)
Query Neighborhood Hits	247	Target Neighborhood Hits	592	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TTF2_MOUSE
θ value	3.17815e-21 (rank : 33)	NC score	0.813178 (rank : 30)
Query Neighborhood Hits	247	Target Neighborhood Hits	364	Shared Neighborhood Hits	83
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRA3_MOUSE
θ value	9.56915e-18 (rank : 34)	NC score	0.727769 (rank : 35)
Query Neighborhood Hits	247	Target Neighborhood Hits	267	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMAL1_HUMAN
θ value	1.63225e-17 (rank : 35)	NC score	0.810866 (rank : 31)
Query Neighborhood Hits	247	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	2.7842e-17 (rank : 36)	NC score	0.819575 (rank : 29)
Query Neighborhood Hits	247	Target Neighborhood Hits	157	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMRA3_HUMAN
θ value	1.38178e-16 (rank : 37)	NC score	0.723242 (rank : 36)
Query Neighborhood Hits	247	Target Neighborhood Hits	265	Shared Neighborhood Hits	43
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

CP250_MOUSE
θ value	0.00298849 (rank : 38)	NC score	0.054266 (rank : 118)
Query Neighborhood Hits	247	Target Neighborhood Hits	1583	Shared Neighborhood Hits	121
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH11_MOUSE
θ value	0.0148317 (rank : 39)	NC score	0.041388 (rank : 189)
Query Neighborhood Hits	247	Target Neighborhood Hits	1777	Shared Neighborhood Hits	130
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NKTR_HUMAN
θ value	0.0148317 (rank : 40)	NC score	0.072099 (rank : 77)
Query Neighborhood Hits	247	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

FYCO1_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.038702 (rank : 203)
Query Neighborhood Hits	247	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MIA2_MOUSE
θ value	0.0252991 (rank : 42)	NC score	0.037913 (rank : 204)
Query Neighborhood Hits	247	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

NMDE1_HUMAN
θ value	0.0252991 (rank : 43)	NC score	0.018892 (rank : 268)
Query Neighborhood Hits	247	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

BRD3_HUMAN
θ value	0.0330416 (rank : 44)	NC score	0.057550 (rank : 102)
Query Neighborhood Hits	247	Target Neighborhood Hits	369	Shared Neighborhood Hits	51
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

CNGA1_MOUSE
θ value	0.0330416 (rank : 45)	NC score	0.021242 (rank : 256)
Query Neighborhood Hits	247	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CP250_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.052802 (rank : 124)
Query Neighborhood Hits	247	Target Neighborhood Hits	1805	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

SMC4_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.046581 (rank : 165)
Query Neighborhood Hits	247	Target Neighborhood Hits	830	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

AFF4_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.072056 (rank : 78)
Query Neighborhood Hits	247	Target Neighborhood Hits	611	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CROCC_HUMAN
θ value	0.0431538 (rank : 49)	NC score	0.046980 (rank : 162)
Query Neighborhood Hits	247	Target Neighborhood Hits	1409	Shared Neighborhood Hits	111
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SMC4_HUMAN
θ value	0.0563607 (rank : 50)	NC score	0.049187 (rank : 152)
Query Neighborhood Hits	247	Target Neighborhood Hits	937	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

CROCC_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.048523 (rank : 157)
Query Neighborhood Hits	247	Target Neighborhood Hits	1460	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HDAC5_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.034556 (rank : 220)
Query Neighborhood Hits	247	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

MYH11_HUMAN
θ value	0.0736092 (rank : 53)	NC score	0.044812 (rank : 171)
Query Neighborhood Hits	247	Target Neighborhood Hits	1806	Shared Neighborhood Hits	137
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

UBP42_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.016459 (rank : 282)
Query Neighborhood Hits	247	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

AFF4_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.067943 (rank : 82)
Query Neighborhood Hits	247	Target Neighborhood Hits	581	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

HDAC5_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.035251 (rank : 216)
Query Neighborhood Hits	247	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

RAD50_MOUSE
θ value	0.125558 (rank : 57)	NC score	0.054195 (rank : 119)
Query Neighborhood Hits	247	Target Neighborhood Hits	1366	Shared Neighborhood Hits	125
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

BRD3_MOUSE
θ value	0.163984 (rank : 58)	NC score	0.059925 (rank : 99)
Query Neighborhood Hits	247	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

IF4G3_MOUSE
θ value	0.163984 (rank : 59)	NC score	0.024470 (rank : 245)
Query Neighborhood Hits	247	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PRP4B_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.012364 (rank : 290)
Query Neighborhood Hits	247	Target Neighborhood Hits	1030	Shared Neighborhood Hits	55
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TCAL5_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.082545 (rank : 64)
Query Neighborhood Hits	247	Target Neighborhood Hits	806	Shared Neighborhood Hits	79
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

MYH14_MOUSE
θ value	0.21417 (rank : 62)	NC score	0.032774 (rank : 225)
Query Neighborhood Hits	247	Target Neighborhood Hits	1225	Shared Neighborhood Hits	101
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PCLO_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.043682 (rank : 178)
Query Neighborhood Hits	247	Target Neighborhood Hits	2275	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PININ_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.047056 (rank : 161)
Query Neighborhood Hits	247	Target Neighborhood Hits	753	Shared Neighborhood Hits	94
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PRP4B_MOUSE
θ value	0.21417 (rank : 65)	NC score	0.013888 (rank : 285)
Query Neighborhood Hits	247	Target Neighborhood Hits	1040	Shared Neighborhood Hits	54
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

BRD4_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.056785 (rank : 108)
Query Neighborhood Hits	247	Target Neighborhood Hits	851	Shared Neighborhood Hits	80
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

NMDE1_MOUSE
θ value	0.279714 (rank : 67)	NC score	0.016183 (rank : 283)
Query Neighborhood Hits	247	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NOLC1_HUMAN
θ value	0.279714 (rank : 68)	NC score	0.048694 (rank : 155)
Query Neighborhood Hits	247	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PRP40_MOUSE
θ value	0.279714 (rank : 69)	NC score	0.060169 (rank : 96)
Query Neighborhood Hits	247	Target Neighborhood Hits	447	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RBBP6_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.095643 (rank : 44)
Query Neighborhood Hits	247	Target Neighborhood Hits	1135	Shared Neighborhood Hits	122
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

LZTS1_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.040809 (rank : 194)
Query Neighborhood Hits	247	Target Neighborhood Hits	532	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LZTS1_MOUSE
θ value	0.365318 (rank : 72)	NC score	0.044189 (rank : 175)
Query Neighborhood Hits	247	Target Neighborhood Hits	540	Shared Neighborhood Hits	68
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

P85A_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.019518 (rank : 264)
Query Neighborhood Hits	247	Target Neighborhood Hits	479	Shared Neighborhood Hits	41
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SPAT7_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.025844 (rank : 242)
Query Neighborhood Hits	247	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VP2, Q8BK23	Gene names	Spata7
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 homolog.

WWP2_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.008803 (rank : 301)
Query Neighborhood Hits	247	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

BRD4_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.057508 (rank : 103)
Query Neighborhood Hits	247	Target Neighborhood Hits	845	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CD2L2_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.009434 (rank : 300)
Query Neighborhood Hits	247	Target Neighborhood Hits	1439	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

GOGA2_MOUSE
θ value	0.47712 (rank : 78)	NC score	0.040352 (rank : 195)
Query Neighborhood Hits	247	Target Neighborhood Hits	944	Shared Neighborhood Hits	83
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

HDAC4_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.029298 (rank : 236)
Query Neighborhood Hits	247	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

KI21A_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.036156 (rank : 211)
Query Neighborhood Hits	247	Target Neighborhood Hits	1543	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

NKTR_MOUSE
θ value	0.47712 (rank : 81)	NC score	0.051299 (rank : 140)
Query Neighborhood Hits	247	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

OXR1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.042474 (rank : 181)
Query Neighborhood Hits	247	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

RABE1_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.055122 (rank : 115)
Query Neighborhood Hits	247	Target Neighborhood Hits	1105	Shared Neighborhood Hits	112
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

ROCK2_MOUSE
θ value	0.47712 (rank : 84)	NC score	0.019569 (rank : 263)
Query Neighborhood Hits	247	Target Neighborhood Hits	2072	Shared Neighborhood Hits	123
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

TR150_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.056003 (rank : 114)
Query Neighborhood Hits	247	Target Neighborhood Hits	313	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ANXA3_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.010143 (rank : 296)
Query Neighborhood Hits	247	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O35639	Gene names	Anxa3, Anx3
Domain Architecture
Description	Annexin A3 (Annexin III) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) (35-alpha calcimedin).

CN145_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.043919 (rank : 176)
Query Neighborhood Hits	247	Target Neighborhood Hits	916	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

DPOLZ_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.017379 (rank : 277)
Query Neighborhood Hits	247	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

GOGA1_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.043175 (rank : 179)
Query Neighborhood Hits	247	Target Neighborhood Hits	994	Shared Neighborhood Hits	97
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

KTN1_HUMAN
θ value	0.62314 (rank : 90)	NC score	0.037507 (rank : 205)
Query Neighborhood Hits	247	Target Neighborhood Hits	1197	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MMTA2_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.028528 (rank : 237)
Query Neighborhood Hits	247	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

P85A_MOUSE
θ value	0.62314 (rank : 92)	NC score	0.018025 (rank : 275)
Query Neighborhood Hits	247	Target Neighborhood Hits	435	Shared Neighborhood Hits	32
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TF3C3_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.026248 (rank : 241)
Query Neighborhood Hits	247	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

THOC2_HUMAN
θ value	0.62314 (rank : 94)	NC score	0.057036 (rank : 107)
Query Neighborhood Hits	247	Target Neighborhood Hits	337	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

CIR_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.042795 (rank : 180)
Query Neighborhood Hits	247	Target Neighborhood Hits	249	Shared Neighborhood Hits	48
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

GOGA2_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.039406 (rank : 199)
Query Neighborhood Hits	247	Target Neighborhood Hits	856	Shared Neighborhood Hits	76
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HIRP3_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.091167 (rank : 51)
Query Neighborhood Hits	247	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HMMR_MOUSE
θ value	0.813845 (rank : 98)	NC score	0.040924 (rank : 192)
Query Neighborhood Hits	247	Target Neighborhood Hits	1178	Shared Neighborhood Hits	112
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

PRP40_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.056234 (rank : 112)
Query Neighborhood Hits	247	Target Neighborhood Hits	442	Shared Neighborhood Hits	77
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

RB6I2_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.051892 (rank : 134)
Query Neighborhood Hits	247	Target Neighborhood Hits	1584	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SKIL_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.041782 (rank : 186)
Query Neighborhood Hits	247	Target Neighborhood Hits	719	Shared Neighborhood Hits	87
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SYCP1_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.048571 (rank : 156)
Query Neighborhood Hits	247	Target Neighborhood Hits	1456	Shared Neighborhood Hits	135
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP2_HUMAN
θ value	0.813845 (rank : 103)	NC score	0.064912 (rank : 86)
Query Neighborhood Hits	247	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

CING_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.041456 (rank : 187)
Query Neighborhood Hits	247	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CTR9_MOUSE
θ value	1.06291 (rank : 105)	NC score	0.037356 (rank : 206)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

EP15_MOUSE
θ value	1.06291 (rank : 106)	NC score	0.034263 (rank : 222)
Query Neighborhood Hits	247	Target Neighborhood Hits	820	Shared Neighborhood Hits	79
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GSK3A_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.002712 (rank : 316)
Query Neighborhood Hits	247	Target Neighborhood Hits	835	Shared Neighborhood Hits	15
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

HPS1_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.018445 (rank : 271)
Query Neighborhood Hits	247	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	O08983, O35155, O35725, O35950	Gene names	Hps1, Ep, Hps
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 1 protein homolog.

LYAR_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.029811 (rank : 234)
Query Neighborhood Hits	247	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

MYH13_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.037113 (rank : 208)
Query Neighborhood Hits	247	Target Neighborhood Hits	1504	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NOP14_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.074287 (rank : 73)
Query Neighborhood Hits	247	Target Neighborhood Hits	573	Shared Neighborhood Hits	104
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

PCNT_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.039668 (rank : 196)
Query Neighborhood Hits	247	Target Neighborhood Hits	1551	Shared Neighborhood Hits	117
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ANGP2_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.017864 (rank : 276)
Query Neighborhood Hits	247	Target Neighborhood Hits	400	Shared Neighborhood Hits	60
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

APBA1_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.009651 (rank : 299)
Query Neighborhood Hits	247	Target Neighborhood Hits	325	Shared Neighborhood Hits	15
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CAF1A_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.046419 (rank : 166)
Query Neighborhood Hits	247	Target Neighborhood Hits	736	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ESCO1_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.048997 (rank : 153)
Query Neighborhood Hits	247	Target Neighborhood Hits	361	Shared Neighborhood Hits	76
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

GOGA3_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.041103 (rank : 191)
Query Neighborhood Hits	247	Target Neighborhood Hits	1317	Shared Neighborhood Hits	109
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA4_HUMAN
θ value	1.38821 (rank : 118)	NC score	0.045831 (rank : 169)
Query Neighborhood Hits	247	Target Neighborhood Hits	2034	Shared Neighborhood Hits	142
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GSK3B_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.002682 (rank : 318)
Query Neighborhood Hits	247	Target Neighborhood Hits	801	Shared Neighborhood Hits	15
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.002683 (rank : 317)
Query Neighborhood Hits	247	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

JARD2_MOUSE
θ value	1.38821 (rank : 121)	NC score	0.014268 (rank : 284)
Query Neighborhood Hits	247	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

NFH_MOUSE
θ value	1.38821 (rank : 122)	NC score	0.052616 (rank : 125)
Query Neighborhood Hits	247	Target Neighborhood Hits	2247	Shared Neighborhood Hits	149
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF14_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.062303 (rank : 91)
Query Neighborhood Hits	247	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

ANXA3_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.008634 (rank : 304)
Query Neighborhood Hits	247	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P12429, Q6LET2	Gene names	ANXA3, ANX3
Domain Architecture
Description	Annexin A3 (Annexin III) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) (35-alpha calcimedin) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase).

BPTF_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.112109 (rank : 38)
Query Neighborhood Hits	247	Target Neighborhood Hits	786	Shared Neighborhood Hits	81
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CASC3_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.029746 (rank : 235)
Query Neighborhood Hits	247	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CDKL3_MOUSE
θ value	1.81305 (rank : 127)	NC score	-0.000083 (rank : 320)
Query Neighborhood Hits	247	Target Neighborhood Hits	857	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

CS007_HUMAN
θ value	1.81305 (rank : 128)	NC score	0.021934 (rank : 253)
Query Neighborhood Hits	247	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

GPTC8_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.036053 (rank : 212)
Query Neighborhood Hits	247	Target Neighborhood Hits	366	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IWS1_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.095534 (rank : 45)
Query Neighborhood Hits	247	Target Neighborhood Hits	1241	Shared Neighborhood Hits	107
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NOP14_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.042374 (rank : 183)
Query Neighborhood Hits	247	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

RGS12_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.010778 (rank : 293)
Query Neighborhood Hits	247	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

SNIP1_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.034717 (rank : 219)
Query Neighborhood Hits	247	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

TOP1_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.035278 (rank : 214)
Query Neighborhood Hits	247	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ANGP2_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.018905 (rank : 267)
Query Neighborhood Hits	247	Target Neighborhood Hits	397	Shared Neighborhood Hits	61
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

AP3B2_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.021800 (rank : 254)
Query Neighborhood Hits	247	Target Neighborhood Hits	246	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CAF1A_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.041795 (rank : 185)
Query Neighborhood Hits	247	Target Neighborhood Hits	750	Shared Neighborhood Hits	80
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DDX25_MOUSE
θ value	2.36792 (rank : 138)	NC score	0.020706 (rank : 261)
Query Neighborhood Hits	247	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

FA44A_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.033009 (rank : 224)
Query Neighborhood Hits	247	Target Neighborhood Hits	280	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

IFT81_MOUSE
θ value	2.36792 (rank : 140)	NC score	0.047657 (rank : 160)
Query Neighborhood Hits	247	Target Neighborhood Hits	959	Shared Neighborhood Hits	106
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

LEO1_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.090951 (rank : 53)
Query Neighborhood Hits	247	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MAP1B_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.040888 (rank : 193)
Query Neighborhood Hits	247	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MKL2_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.011822 (rank : 291)
Query Neighborhood Hits	247	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MY18A_MOUSE
θ value	2.36792 (rank : 144)	NC score	0.048234 (rank : 159)
Query Neighborhood Hits	247	Target Neighborhood Hits	1989	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NALP5_MOUSE
θ value	2.36792 (rank : 145)	NC score	0.038932 (rank : 202)
Query Neighborhood Hits	247	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

SMC3_MOUSE
θ value	2.36792 (rank : 146)	NC score	0.045937 (rank : 168)
Query Neighborhood Hits	247	Target Neighborhood Hits	1187	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

UACA_HUMAN
θ value	2.36792 (rank : 147)	NC score	0.035017 (rank : 217)
Query Neighborhood Hits	247	Target Neighborhood Hits	1622	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UN84A_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.019464 (rank : 265)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	41
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

ZCHC7_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.028156 (rank : 238)
Query Neighborhood Hits	247	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

ANR12_HUMAN
θ value	3.0926 (rank : 150)	NC score	0.031359 (rank : 230)
Query Neighborhood Hits	247	Target Neighborhood Hits	1081	Shared Neighborhood Hits	129
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CR034_HUMAN
θ value	3.0926 (rank : 151)	NC score	0.032444 (rank : 226)
Query Neighborhood Hits	247	Target Neighborhood Hits	538	Shared Neighborhood Hits	69
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

DJBP_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.010309 (rank : 295)
Query Neighborhood Hits	247	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

NUMA1_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.039303 (rank : 200)
Query Neighborhood Hits	247	Target Neighborhood Hits	1523	Shared Neighborhood Hits	113
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

P85B_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.024549 (rank : 244)
Query Neighborhood Hits	247	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RSRC1_MOUSE
θ value	3.0926 (rank : 155)	NC score	0.026551 (rank : 240)
Query Neighborhood Hits	247	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SFR12_HUMAN
θ value	3.0926 (rank : 156)	NC score	0.042398 (rank : 182)
Query Neighborhood Hits	247	Target Neighborhood Hits	553	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SMC3_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.045543 (rank : 170)
Query Neighborhood Hits	247	Target Neighborhood Hits	1186	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

ARS2_MOUSE
θ value	4.03905 (rank : 158)	NC score	0.035262 (rank : 215)
Query Neighborhood Hits	247	Target Neighborhood Hits	212	Shared Neighborhood Hits	33
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CASC3_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.034265 (rank : 221)
Query Neighborhood Hits	247	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

CD2L1_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.007093 (rank : 311)
Query Neighborhood Hits	247	Target Neighborhood Hits	1467	Shared Neighborhood Hits	83
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CS007_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.016974 (rank : 280)
Query Neighborhood Hits	247	Target Neighborhood Hits	464	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

DDX3Y_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.027727 (rank : 239)
Query Neighborhood Hits	247	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

E2AK4_MOUSE
θ value	4.03905 (rank : 163)	NC score	-0.000283 (rank : 321)
Query Neighborhood Hits	247	Target Neighborhood Hits	984	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

EEA1_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.046164 (rank : 167)
Query Neighborhood Hits	247	Target Neighborhood Hits	1637	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FIP1_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.019672 (rank : 262)
Query Neighborhood Hits	247	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

FIP1_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.018919 (rank : 266)
Query Neighborhood Hits	247	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

HOOK3_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.036720 (rank : 209)
Query Neighborhood Hits	247	Target Neighborhood Hits	1070	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MY18A_HUMAN
θ value	4.03905 (rank : 168)	NC score	0.052205 (rank : 129)
Query Neighborhood Hits	247	Target Neighborhood Hits	1929	Shared Neighborhood Hits	152
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NIP30_MOUSE
θ value	4.03905 (rank : 169)	NC score	0.021095 (rank : 257)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

OXR1_MOUSE
θ value	4.03905 (rank : 170)	NC score	0.057741 (rank : 101)
Query Neighborhood Hits	247	Target Neighborhood Hits	516	Shared Neighborhood Hits	74
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

RABE1_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.051052 (rank : 142)
Query Neighborhood Hits	247	Target Neighborhood Hits	1104	Shared Neighborhood Hits	111
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RIPK4_HUMAN
θ value	4.03905 (rank : 172)	NC score	-0.003889 (rank : 324)
Query Neighborhood Hits	247	Target Neighborhood Hits	1094	Shared Neighborhood Hits	18
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RREB1_HUMAN
θ value	4.03905 (rank : 173)	NC score	-0.001559 (rank : 322)
Query Neighborhood Hits	247	Target Neighborhood Hits	879	Shared Neighborhood Hits	20
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

S25BP_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.021010 (rank : 259)
Query Neighborhood Hits	247	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	O95295	Gene names	SNAPAP, SNAP25BP
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

S25BP_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.021012 (rank : 258)
Query Neighborhood Hits	247	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z266, Q3U8V4, Q922V7	Gene names	Snapap, Snap25bp
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

SYTL1_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.007785 (rank : 307)
Query Neighborhood Hits	247	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

ADDB_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.041398 (rank : 188)
Query Neighborhood Hits	247	Target Neighborhood Hits	574	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AP3D1_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.022093 (rank : 250)
Query Neighborhood Hits	247	Target Neighborhood Hits	254	Shared Neighborhood Hits	30
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

ARS2_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.039494 (rank : 197)
Query Neighborhood Hits	247	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

CN145_HUMAN
θ value	5.27518 (rank : 180)	NC score	0.044437 (rank : 172)
Query Neighborhood Hits	247	Target Neighborhood Hits	1196	Shared Neighborhood Hits	118
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNTN6_MOUSE
θ value	5.27518 (rank : 181)	NC score	-0.001783 (rank : 323)
Query Neighborhood Hits	247	Target Neighborhood Hits	429	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

EP15R_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.039449 (rank : 198)
Query Neighborhood Hits	247	Target Neighborhood Hits	1083	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GCC2_HUMAN
θ value	5.27518 (rank : 183)	NC score	0.044338 (rank : 173)
Query Neighborhood Hits	247	Target Neighborhood Hits	1558	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GTSE1_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.011802 (rank : 292)
Query Neighborhood Hits	247	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HDAC9_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.031280 (rank : 231)
Query Neighborhood Hits	247	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

MBD6_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.007449 (rank : 310)
Query Neighborhood Hits	247	Target Neighborhood Hits	349	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

NIP30_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.018666 (rank : 270)
Query Neighborhood Hits	247	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZU8	Gene names	NIP30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

PAHX_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.010693 (rank : 294)
Query Neighborhood Hits	247	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O14832	Gene names	PHYH, PAHX
Domain Architecture
Description	Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC 1.14.11.18) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase).

PALM_MOUSE
θ value	5.27518 (rank : 189)	NC score	0.018280 (rank : 273)
Query Neighborhood Hits	247	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

PEPL_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.035006 (rank : 218)
Query Neighborhood Hits	247	Target Neighborhood Hits	1141	Shared Neighborhood Hits	107
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PLCB3_MOUSE
θ value	5.27518 (rank : 191)	NC score	0.013167 (rank : 287)
Query Neighborhood Hits	247	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

RAD50_HUMAN
θ value	5.27518 (rank : 192)	NC score	0.048251 (rank : 158)
Query Neighborhood Hits	247	Target Neighborhood Hits	1317	Shared Neighborhood Hits	113
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RASF8_HUMAN
θ value	5.27518 (rank : 193)	NC score	0.029908 (rank : 233)
Query Neighborhood Hits	247	Target Neighborhood Hits	469	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

RBP24_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.044328 (rank : 174)
Query Neighborhood Hits	247	Target Neighborhood Hits	1559	Shared Neighborhood Hits	117
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RRBP1_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.048931 (rank : 154)
Query Neighborhood Hits	247	Target Neighborhood Hits	1306	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SFRS4_MOUSE
θ value	5.27518 (rank : 196)	NC score	0.022492 (rank : 248)
Query Neighborhood Hits	247	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TEX9_MOUSE
θ value	5.27518 (rank : 197)	NC score	0.031732 (rank : 228)
Query Neighborhood Hits	247	Target Neighborhood Hits	581	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TRAF3_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.021949 (rank : 252)
Query Neighborhood Hits	247	Target Neighborhood Hits	463	Shared Neighborhood Hits	58
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	5.27518 (rank : 199)	NC score	0.022259 (rank : 249)
Query Neighborhood Hits	247	Target Neighborhood Hits	476	Shared Neighborhood Hits	61
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

CI039_HUMAN
θ value	6.88961 (rank : 200)	NC score	0.056749 (rank : 109)
Query Neighborhood Hits	247	Target Neighborhood Hits	1171	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CJ012_HUMAN
θ value	6.88961 (rank : 201)	NC score	0.051916 (rank : 133)
Query Neighborhood Hits	247	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CNGA1_HUMAN
θ value	6.88961 (rank : 202)	NC score	0.013131 (rank : 288)
Query Neighborhood Hits	247	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CNGB3_HUMAN
θ value	6.88961 (rank : 203)	NC score	0.013188 (rank : 286)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

EEA1_HUMAN
θ value	6.88961 (rank : 204)	NC score	0.043697 (rank : 177)
Query Neighborhood Hits	247	Target Neighborhood Hits	1796	Shared Neighborhood Hits	127
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ERCC5_MOUSE
θ value	6.88961 (rank : 205)	NC score	0.012595 (rank : 289)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

IF2P_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.052277 (rank : 127)
Query Neighborhood Hits	247	Target Neighborhood Hits	889	Shared Neighborhood Hits	93
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

K2C7_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.008699 (rank : 303)
Query Neighborhood Hits	247	Target Neighborhood Hits	369	Shared Neighborhood Hits	59
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

KTNA1_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.004944 (rank : 313)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

MYH9_MOUSE
θ value	6.88961 (rank : 209)	NC score	0.036175 (rank : 210)
Query Neighborhood Hits	247	Target Neighborhood Hits	1829	Shared Neighborhood Hits	128
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

RBBP6_MOUSE
θ value	6.88961 (rank : 210)	NC score	0.092185 (rank : 50)
Query Neighborhood Hits	247	Target Neighborhood Hits	1014	Shared Neighborhood Hits	106
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBM25_HUMAN
θ value	6.88961 (rank : 211)	NC score	0.057073 (rank : 106)
Query Neighborhood Hits	247	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TCOF_HUMAN
θ value	6.88961 (rank : 212)	NC score	0.025121 (rank : 243)
Query Neighborhood Hits	247	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TPR_HUMAN
θ value	6.88961 (rank : 213)	NC score	0.046826 (rank : 164)
Query Neighborhood Hits	247	Target Neighborhood Hits	1921	Shared Neighborhood Hits	137
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZN291_HUMAN
θ value	6.88961 (rank : 214)	NC score	0.033221 (rank : 223)
Query Neighborhood Hits	247	Target Neighborhood Hits	647	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

BAP31_HUMAN
θ value	8.99809 (rank : 215)	NC score	0.016719 (rank : 281)
Query Neighborhood Hits	247	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

CCD11_HUMAN
θ value	8.99809 (rank : 216)	NC score	0.035841 (rank : 213)
Query Neighborhood Hits	247	Target Neighborhood Hits	822	Shared Neighborhood Hits	100
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CD2L1_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.008715 (rank : 302)
Query Neighborhood Hits	247	Target Neighborhood Hits	1463	Shared Neighborhood Hits	89
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

DLG7_MOUSE
θ value	8.99809 (rank : 218)	NC score	0.007611 (rank : 309)
Query Neighborhood Hits	247	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

DMP1_HUMAN
θ value	8.99809 (rank : 219)	NC score	0.046876 (rank : 163)
Query Neighborhood Hits	247	Target Neighborhood Hits	491	Shared Neighborhood Hits	62
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	8.99809 (rank : 220)	NC score	0.061564 (rank : 93)
Query Neighborhood Hits	247	Target Neighborhood Hits	498	Shared Neighborhood Hits	53
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

EP15R_MOUSE
θ value	8.99809 (rank : 221)	NC score	0.039074 (rank : 201)
Query Neighborhood Hits	247	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

GRAP1_HUMAN
θ value	8.99809 (rank : 222)	NC score	0.031594 (rank : 229)
Query Neighborhood Hits	247	Target Neighborhood Hits	944	Shared Neighborhood Hits	91
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HERC2_HUMAN
θ value	8.99809 (rank : 223)	NC score	0.002990 (rank : 315)
Query Neighborhood Hits	247	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

HOOK3_MOUSE
θ value	8.99809 (rank : 224)	NC score	0.037230 (rank : 207)
Query Neighborhood Hits	247	Target Neighborhood Hits	1007	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

IF4A1_HUMAN
θ value	8.99809 (rank : 225)	NC score	0.008488 (rank : 305)
Query Neighborhood Hits	247	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	8.99809 (rank : 226)	NC score	0.008488 (rank : 306)
Query Neighborhood Hits	247	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

ITSN2_HUMAN
θ value	8.99809 (rank : 227)	NC score	0.017379 (rank : 278)
Query Neighborhood Hits	247	Target Neighborhood Hits	1173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

K0562_MOUSE
θ value	8.99809 (rank : 228)	NC score	0.006725 (rank : 312)
Query Neighborhood Hits	247	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

K1958_HUMAN
θ value	8.99809 (rank : 229)	NC score	0.007757 (rank : 308)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

KIF11_HUMAN
θ value	8.99809 (rank : 230)	NC score	0.018214 (rank : 274)
Query Neighborhood Hits	247	Target Neighborhood Hits	583	Shared Neighborhood Hits	69
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

MOES_HUMAN
θ value	8.99809 (rank : 231)	NC score	0.021360 (rank : 255)
Query Neighborhood Hits	247	Target Neighborhood Hits	892	Shared Neighborhood Hits	86
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NIN_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.042173 (rank : 184)
Query Neighborhood Hits	247	Target Neighborhood Hits	1416	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIPBL_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.101057 (rank : 40)
Query Neighborhood Hits	247	Target Neighborhood Hits	1311	Shared Neighborhood Hits	133
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PENK_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.010095 (rank : 297)
Query Neighborhood Hits	247	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PENK_MOUSE
θ value	8.99809 (rank : 235)	NC score	0.009910 (rank : 298)
Query Neighborhood Hits	247	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PLCB4_HUMAN
θ value	8.99809 (rank : 236)	NC score	0.030778 (rank : 232)
Query Neighborhood Hits	247	Target Neighborhood Hits	658	Shared Neighborhood Hits	88
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RAI14_HUMAN
θ value	8.99809 (rank : 237)	NC score	0.023208 (rank : 246)
Query Neighborhood Hits	247	Target Neighborhood Hits	1367	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

REST_MOUSE
θ value	8.99809 (rank : 238)	NC score	0.041162 (rank : 190)
Query Neighborhood Hits	247	Target Neighborhood Hits	1506	Shared Neighborhood Hits	121
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ROCK2_HUMAN
θ value	8.99809 (rank : 239)	NC score	0.017078 (rank : 279)
Query Neighborhood Hits	247	Target Neighborhood Hits	2073	Shared Neighborhood Hits	128
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

RSRC1_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.022998 (rank : 247)
Query Neighborhood Hits	247	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SEZ6L_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.002110 (rank : 319)
Query Neighborhood Hits	247	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SPTA1_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.020808 (rank : 260)
Query Neighborhood Hits	247	Target Neighborhood Hits	748	Shared Neighborhood Hits	70
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.022088 (rank : 251)
Query Neighborhood Hits	247	Target Neighborhood Hits	675	Shared Neighborhood Hits	73
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SYNE1_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.031746 (rank : 227)
Query Neighborhood Hits	247	Target Neighborhood Hits	1484	Shared Neighborhood Hits	106
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TNIK_HUMAN
θ value	8.99809 (rank : 245)	NC score	0.003447 (rank : 314)
Query Neighborhood Hits	247	Target Neighborhood Hits	1570	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TOPRS_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.018716 (rank : 269)
Query Neighborhood Hits	247	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

WDR60_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.018398 (rank : 272)
Query Neighborhood Hits	247	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

AIRE_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.099792 (rank : 42)
Query Neighborhood Hits	247	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.100857 (rank : 41)
Query Neighborhood Hits	247	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AKA12_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.064679 (rank : 87)
Query Neighborhood Hits	247	Target Neighborhood Hits	825	Shared Neighborhood Hits	113
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.091065 (rank : 52)
Query Neighborhood Hits	247	Target Neighborhood Hits	693	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.088661 (rank : 59)
Query Neighborhood Hits	247	Target Neighborhood Hits	701	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.090407 (rank : 54)
Query Neighborhood Hits	247	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.062295 (rank : 92)
Query Neighborhood Hits	247	Target Neighborhood Hits	780	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.060102 (rank : 97)
Query Neighborhood Hits	247	Target Neighborhood Hits	744	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.077722 (rank : 69)
Query Neighborhood Hits	247	Target Neighborhood Hits	803	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD1_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.054974 (rank : 116)
Query Neighborhood Hits	247	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.050415 (rank : 147)
Query Neighborhood Hits	247	Target Neighborhood Hits	259	Shared Neighborhood Hits	30
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRPF3_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.051826 (rank : 135)
Query Neighborhood Hits	247	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

C8AP2_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.051796 (rank : 136)
Query Neighborhood Hits	247	Target Neighborhood Hits	548	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.065286 (rank : 84)
Query Neighborhood Hits	247	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.065286 (rank : 85)
Query Neighborhood Hits	247	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.057222 (rank : 104)
Query Neighborhood Hits	247	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.060295 (rank : 94)
Query Neighborhood Hits	247	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.080168 (rank : 66)
Query Neighborhood Hits	247	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.071336 (rank : 79)
Query Neighborhood Hits	247	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX7_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.057083 (rank : 105)
Query Neighborhood Hits	247	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.060247 (rank : 95)
Query Neighborhood Hits	247	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CCD55_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.052078 (rank : 131)
Query Neighborhood Hits	247	Target Neighborhood Hits	513	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CCD55_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.059523 (rank : 100)
Query Neighborhood Hits	247	Target Neighborhood Hits	519	Shared Neighborhood Hits	92
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CF010_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.052230 (rank : 128)
Query Neighborhood Hits	247	Target Neighborhood Hits	329	Shared Neighborhood Hits	67
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CP135_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.050766 (rank : 144)
Query Neighborhood Hits	247	Target Neighborhood Hits	1278	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CYLC1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.052107 (rank : 130)
Query Neighborhood Hits	247	Target Neighborhood Hits	408	Shared Neighborhood Hits	53
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DPF1_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.053812 (rank : 120)
Query Neighborhood Hits	247	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

GOGB1_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.050641 (rank : 146)
Query Neighborhood Hits	247	Target Neighborhood Hits	2297	Shared Neighborhood Hits	156
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IWS1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.097463 (rank : 43)
Query Neighborhood Hits	247	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KMHN1_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.050098 (rank : 150)
Query Neighborhood Hits	247	Target Neighborhood Hits	949	Shared Neighborhood Hits	109
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LEO1_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.089519 (rank : 55)
Query Neighborhood Hits	247	Target Neighborhood Hits	958	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LY10_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.072792 (rank : 76)
Query Neighborhood Hits	247	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MAP1A_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.052300 (rank : 126)
Query Neighborhood Hits	247	Target Neighborhood Hits	1626	Shared Neighborhood Hits	142
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MLL2_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.056287 (rank : 111)
Query Neighborhood Hits	247	Target Neighborhood Hits	1788	Shared Neighborhood Hits	83
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.056369 (rank : 110)
Query Neighborhood Hits	247	Target Neighborhood Hits	1644	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.051604 (rank : 138)
Query Neighborhood Hits	247	Target Neighborhood Hits	1399	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MPP8_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.068551 (rank : 81)
Query Neighborhood Hits	247	Target Neighborhood Hits	948	Shared Neighborhood Hits	124
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NPBL_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.088901 (rank : 58)
Query Neighborhood Hits	247	Target Neighborhood Hits	1041	Shared Neighborhood Hits	114
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.062545 (rank : 90)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.064467 (rank : 88)
Query Neighborhood Hits	247	Target Neighborhood Hits	472	Shared Neighborhood Hits	24
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

OPTN_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.052061 (rank : 132)
Query Neighborhood Hits	247	Target Neighborhood Hits	1120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PB1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.060086 (rank : 98)
Query Neighborhood Hits	247	Target Neighborhood Hits	261	Shared Neighborhood Hits	11
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PF21A_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.088466 (rank : 60)
Query Neighborhood Hits	247	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.089511 (rank : 56)
Query Neighborhood Hits	247	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.089302 (rank : 57)
Query Neighborhood Hits	247	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.087855 (rank : 62)
Query Neighborhood Hits	247	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.051111 (rank : 141)
Query Neighborhood Hits	247	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF12_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.094545 (rank : 47)
Query Neighborhood Hits	247	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.095079 (rank : 46)
Query Neighborhood Hits	247	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF14_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.053016 (rank : 122)
Query Neighborhood Hits	247	Target Neighborhood Hits	342	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF20_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.069584 (rank : 80)
Query Neighborhood Hits	247	Target Neighborhood Hits	394	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.074663 (rank : 72)
Query Neighborhood Hits	247	Target Neighborhood Hits	513	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PKCB1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.101535 (rank : 39)
Query Neighborhood Hits	247	Target Neighborhood Hits	488	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PPIG_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.052903 (rank : 123)
Query Neighborhood Hits	247	Target Neighborhood Hits	670	Shared Neighborhood Hits	109
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RRBP1_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.063335 (rank : 89)
Query Neighborhood Hits	247	Target Neighborhood Hits	1650	Shared Neighborhood Hits	152
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RSF1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.093292 (rank : 48)
Query Neighborhood Hits	247	Target Neighborhood Hits	539	Shared Neighborhood Hits	72
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SEMG2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.050270 (rank : 149)
Query Neighborhood Hits	247	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SM1L2_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.050744 (rank : 145)
Query Neighborhood Hits	247	Target Neighborhood Hits	1019	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC1A_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.053409 (rank : 121)
Query Neighborhood Hits	247	Target Neighborhood Hits	1384	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC2_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.051389 (rank : 139)
Query Neighborhood Hits	247	Target Neighborhood Hits	1405	Shared Neighborhood Hits	133
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SP110_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.076904 (rank : 70)
Query Neighborhood Hits	247	Target Neighborhood Hits	141	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TGON2_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.092214 (rank : 49)
Query Neighborhood Hits	247	Target Neighborhood Hits	1037	Shared Neighborhood Hits	86
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1A_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.072898 (rank : 75)
Query Neighborhood Hits	247	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.075571 (rank : 71)
Query Neighborhood Hits	247	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.066799 (rank : 83)
Query Neighborhood Hits	247	Target Neighborhood Hits	410	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.074140 (rank : 74)
Query Neighborhood Hits	247	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TR150_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.056112 (rank : 113)
Query Neighborhood Hits	247	Target Neighborhood Hits	468	Shared Neighborhood Hits	81
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRI66_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.078579 (rank : 68)
Query Neighborhood Hits	247	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.078980 (rank : 67)
Query Neighborhood Hits	247	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.088375 (rank : 61)
Query Neighborhood Hits	247	Target Neighborhood Hits	828	Shared Neighborhood Hits	103
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UHRF1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.050326 (rank : 148)
Query Neighborhood Hits	247	Target Neighborhood Hits	272	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.054366 (rank : 117)
Query Neighborhood Hits	247	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.050070 (rank : 151)
Query Neighborhood Hits	247	Target Neighborhood Hits	275	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

YTDC1_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.051729 (rank : 137)
Query Neighborhood Hits	247	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

ZC313_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.051039 (rank : 143)
Query Neighborhood Hits	247	Target Neighborhood Hits	772	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZMY11_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.084993 (rank : 63)
Query Neighborhood Hits	247	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.082521 (rank : 65)
Query Neighborhood Hits	247	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

ERCC6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	247	Target Neighborhood Hits	247	Shared Neighborhood Hits	247
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

RAD54_HUMAN
NC score	0.946990 (rank : 2)	θ value	3.23591e-74 (rank : 6)
Query Neighborhood Hits	247	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RA54B_HUMAN
NC score	0.946502 (rank : 3)	θ value	1.60597e-73 (rank : 7)
Query Neighborhood Hits	247	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_MOUSE
NC score	0.946116 (rank : 4)	θ value	1.35953e-72 (rank : 9)
Query Neighborhood Hits	247	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RA54B_MOUSE
NC score	0.944502 (rank : 5)	θ value	1.15091e-71 (rank : 10)
Query Neighborhood Hits	247	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

BTAF1_HUMAN
NC score	0.944390 (rank : 6)	θ value	4.36332e-79 (rank : 2)
Query Neighborhood Hits	247	Target Neighborhood Hits	97	Shared Neighborhood Hits	41
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMCA5_MOUSE
NC score	0.942190 (rank : 7)	θ value	9.0981e-77 (rank : 4)
Query Neighborhood Hits	247	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.942124 (rank : 8)	θ value	9.0981e-77 (rank : 3)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA1_HUMAN
NC score	0.940883 (rank : 9)	θ value	6.10265e-73 (rank : 8)
Query Neighborhood Hits	247	Target Neighborhood Hits	105	Shared Neighborhood Hits	45
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.939042 (rank : 10)	θ value	1.45253e-74 (rank : 5)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMRCD_HUMAN
NC score	0.938797 (rank : 11)	θ value	2.32439e-64 (rank : 23)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
NC score	0.938587 (rank : 12)	θ value	1.50663e-63 (rank : 24)
Query Neighborhood Hits	247	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD2_HUMAN
NC score	0.922285 (rank : 13)	θ value	1.40689e-69 (rank : 11)
Query Neighborhood Hits	247	Target Neighborhood Hits	360	Shared Neighborhood Hits	76
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_MOUSE
NC score	0.919437 (rank : 14)	θ value	1.71981e-67 (rank : 16)
Query Neighborhood Hits	247	Target Neighborhood Hits	266	Shared Neighborhood Hits	64
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
NC score	0.919073 (rank : 15)	θ value	4.38363e-63 (rank : 25)
Query Neighborhood Hits	247	Target Neighborhood Hits	235	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_HUMAN
NC score	0.918132 (rank : 16)	θ value	3.4653e-68 (rank : 14)
Query Neighborhood Hits	247	Target Neighborhood Hits	337	Shared Neighborhood Hits	74
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
NC score	0.915697 (rank : 17)	θ value	7.2256e-66 (rank : 20)
Query Neighborhood Hits	247	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_HUMAN
NC score	0.910853 (rank : 18)	θ value	7.98882e-65 (rank : 22)
Query Neighborhood Hits	247	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
NC score	0.907487 (rank : 19)	θ value	1.6097e-65 (rank : 21)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMCA2_HUMAN
NC score	0.894446 (rank : 20)	θ value	4.52582e-68 (rank : 15)
Query Neighborhood Hits	247	Target Neighborhood Hits	503	Shared Neighborhood Hits	71
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

INOC1_MOUSE
NC score	0.890484 (rank : 21)	θ value	7.79185e-36 (rank : 27)
Query Neighborhood Hits	247	Target Neighborhood Hits	178	Shared Neighborhood Hits	52
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.890407 (rank : 22)	θ value	5.96599e-36 (rank : 26)
Query Neighborhood Hits	247	Target Neighborhood Hits	181	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SMCA4_HUMAN
NC score	0.883113 (rank : 23)	θ value	6.53529e-67 (rank : 19)
Query Neighborhood Hits	247	Target Neighborhood Hits	597	Shared Neighborhood Hits	78
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

TTF2_HUMAN
NC score	0.859580 (rank : 24)	θ value	1.32909e-35 (rank : 28)
Query Neighborhood Hits	247	Target Neighborhood Hits	98	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

CHD3_HUMAN
NC score	0.856737 (rank : 25)	θ value	1.19101e-68 (rank : 13)
Query Neighborhood Hits	247	Target Neighborhood Hits	397	Shared Neighborhood Hits	58
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.855397 (rank : 26)	θ value	2.93355e-67 (rank : 17)
Query Neighborhood Hits	247	Target Neighborhood Hits	365	Shared Neighborhood Hits	58
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.854208 (rank : 27)	θ value	4.09345e-69 (rank : 12)
Query Neighborhood Hits	247	Target Neighborhood Hits	349	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.852791 (rank : 28)	θ value	2.93355e-67 (rank : 18)
Query Neighborhood Hits	247	Target Neighborhood Hits	408	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMAL1_MOUSE
NC score	0.819575 (rank : 29)	θ value	2.7842e-17 (rank : 36)
Query Neighborhood Hits	247	Target Neighborhood Hits	157	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

TTF2_MOUSE
NC score	0.813178 (rank : 30)	θ value	3.17815e-21 (rank : 33)
Query Neighborhood Hits	247	Target Neighborhood Hits	364	Shared Neighborhood Hits	83
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMAL1_HUMAN
NC score	0.810866 (rank : 31)	θ value	1.63225e-17 (rank : 35)
Query Neighborhood Hits	247	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

EP400_HUMAN
NC score	0.803473 (rank : 32)	θ value	1.2049e-28 (rank : 31)
Query Neighborhood Hits	247	Target Neighborhood Hits	556	Shared Neighborhood Hits	52
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.796193 (rank : 33)	θ value	2.68423e-28 (rank : 32)
Query Neighborhood Hits	247	Target Neighborhood Hits	592	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ATRX_MOUSE
NC score	0.733193 (rank : 34)	θ value	5.22648e-32 (rank : 30)
Query Neighborhood Hits	247	Target Neighborhood Hits	682	Shared Neighborhood Hits	117
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SMRA3_MOUSE
NC score	0.727769 (rank : 35)	θ value	9.56915e-18 (rank : 34)
Query Neighborhood Hits	247	Target Neighborhood Hits	267	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.723242 (rank : 36)	θ value	1.38178e-16 (rank : 37)
Query Neighborhood Hits	247	Target Neighborhood Hits	265	Shared Neighborhood Hits	43
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ATRX_HUMAN
NC score	0.717666 (rank : 37)	θ value	1.37539e-32 (rank : 29)
Query Neighborhood Hits	247	Target Neighborhood Hits	842	Shared Neighborhood Hits	130
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BPTF_HUMAN
NC score	0.112109 (rank : 38)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	247	Target Neighborhood Hits	786	Shared Neighborhood Hits	81
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PKCB1_HUMAN
NC score	0.101535 (rank : 39)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	247	Target Neighborhood Hits	488	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

NIPBL_HUMAN
NC score	0.101057 (rank : 40)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	247	Target Neighborhood Hits	1311	Shared Neighborhood Hits	133
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AIRE_MOUSE
NC score	0.100857 (rank : 41)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	247	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.099792 (rank : 42)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	247	Target Neighborhood Hits	144	Shared Neighborhood Hits	11
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

IWS1_MOUSE
NC score	0.097463 (rank : 43)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	247	Target Neighborhood Hits	1258	Shared Neighborhood Hits	100
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBBP6_HUMAN
NC score	0.095643 (rank : 44)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	247	Target Neighborhood Hits	1135	Shared Neighborhood Hits	122
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

IWS1_HUMAN
NC score	0.095534 (rank : 45)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	247	Target Neighborhood Hits	1241	Shared Neighborhood Hits	107
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PHF12_MOUSE
NC score	0.095079 (rank : 46)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	247	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.094545 (rank : 47)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	247	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RSF1_HUMAN
NC score	0.093292 (rank : 48)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	247	Target Neighborhood Hits	539	Shared Neighborhood Hits	72
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

TGON2_HUMAN
NC score	0.092214 (rank : 49)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	247	Target Neighborhood Hits	1037	Shared Neighborhood Hits	86
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RBBP6_MOUSE
NC score	0.092185 (rank : 50)	θ value	6.88961 (rank : 210)
Query Neighborhood Hits	247	Target Neighborhood Hits	1014	Shared Neighborhood Hits	106
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

HIRP3_HUMAN
NC score	0.091167 (rank : 51)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	247	Target Neighborhood Hits	323	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

BAZ1A_HUMAN
NC score	0.091065 (rank : 52)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	247	Target Neighborhood Hits	693	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

LEO1_MOUSE
NC score	0.090951 (rank : 53)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	247	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

BAZ1B_MOUSE
NC score	0.090407 (rank : 54)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	247	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

LEO1_HUMAN
NC score	0.089519 (rank : 55)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	247	Target Neighborhood Hits	958	Shared Neighborhood Hits	99
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PF21A_MOUSE
NC score	0.089511 (rank : 56)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	247	Target Neighborhood Hits	285	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
NC score	0.089302 (rank : 57)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	247	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

NPBL_MOUSE
NC score	0.088901 (rank : 58)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	247	Target Neighborhood Hits	1041	Shared Neighborhood Hits	114
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

BAZ1B_HUMAN
NC score	0.088661 (rank : 59)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	247	Target Neighborhood Hits	701	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

PF21A_HUMAN
NC score	0.088466 (rank : 60)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	247	Target Neighborhood Hits	303	Shared Neighborhood Hits	31
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TXND2_MOUSE
NC score	0.088375 (rank : 61)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	247	Target Neighborhood Hits	828	Shared Neighborhood Hits	103
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

PF21B_MOUSE
NC score	0.087855 (rank : 62)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	247	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

ZMY11_HUMAN
NC score	0.084993 (rank : 63)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	247	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

TCAL5_HUMAN
NC score	0.082545 (rank : 64)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	247	Target Neighborhood Hits	806	Shared Neighborhood Hits	79
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZMY11_MOUSE
NC score	0.082521 (rank : 65)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	247	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CBX5_HUMAN
NC score	0.080168 (rank : 66)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	247	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

TRI66_MOUSE
NC score	0.078980 (rank : 67)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	247	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.078579 (rank : 68)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	247	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAZ2B_HUMAN
NC score	0.077722 (rank : 69)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	247	Target Neighborhood Hits	803	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

SP110_HUMAN
NC score	0.076904 (rank : 70)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	247	Target Neighborhood Hits	141	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1A_MOUSE
NC score	0.075571 (rank : 71)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	247	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PHF20_MOUSE
NC score	0.074663 (rank : 72)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	247	Target Neighborhood Hits	513	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

NOP14_HUMAN
NC score	0.074287 (rank : 73)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	247	Target Neighborhood Hits	573	Shared Neighborhood Hits	104
SwissProt Accessions	P78316, Q7LGI5, Q7Z6K0, Q8TBR6	Gene names	NOP14, C4orf9
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

TIF1G_MOUSE
NC score	0.074140 (rank : 74)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	247	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1A_HUMAN
NC score	0.072898 (rank : 75)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	247	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

LY10_HUMAN
NC score	0.072792 (rank : 76)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	247	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

NKTR_HUMAN
NC score	0.072099 (rank : 77)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	247	Target Neighborhood Hits	658	Shared Neighborhood Hits	90
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

AFF4_HUMAN
NC score	0.072056 (rank : 78)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	247	Target Neighborhood Hits	611	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CBX5_MOUSE
NC score	0.071336 (rank : 79)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	247	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

PHF20_HUMAN
NC score	0.069584 (rank : 80)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	247	Target Neighborhood Hits	394	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

MPP8_HUMAN
NC score	0.068551 (rank : 81)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	247	Target Neighborhood Hits	948	Shared Neighborhood Hits	124
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

AFF4_MOUSE
NC score	0.067943 (rank : 82)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	247	Target Neighborhood Hits	581	Shared Neighborhood Hits	70
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TIF1G_HUMAN
NC score	0.066799 (rank : 83)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	247	Target Neighborhood Hits	410	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

CBX1_HUMAN
NC score	0.065286 (rank : 84)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	247	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.065286 (rank : 85)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	247	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

SYCP2_HUMAN
NC score	0.064912 (rank : 86)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	247	Target Neighborhood Hits	230	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

AKA12_HUMAN
NC score	0.064679 (rank : 87)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	247	Target Neighborhood Hits	825	Shared Neighborhood Hits	113
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

NSD1_MOUSE
NC score	0.064467 (rank : 88)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	247	Target Neighborhood Hits	472	Shared Neighborhood Hits	24
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RRBP1_MOUSE
NC score	0.063335 (rank : 89)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	247	Target Neighborhood Hits	1650	Shared Neighborhood Hits	152
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

NSD1_HUMAN
NC score	0.062545 (rank : 90)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PHF14_HUMAN
NC score	0.062303 (rank : 91)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	247	Target Neighborhood Hits	447	Shared Neighborhood Hits	60
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

BAZ2A_HUMAN
NC score	0.062295 (rank : 92)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	247	Target Neighborhood Hits	780	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

DMP1_MOUSE
NC score	0.061564 (rank : 93)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	247	Target Neighborhood Hits	498	Shared Neighborhood Hits	53
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

CBX3_MOUSE
NC score	0.060295 (rank : 94)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	247	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX7_MOUSE
NC score	0.060247 (rank : 95)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	247	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

PRP40_MOUSE
NC score	0.060169 (rank : 96)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	247	Target Neighborhood Hits	447	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

BAZ2A_MOUSE
NC score	0.060102 (rank : 97)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	247	Target Neighborhood Hits	744	Shared Neighborhood Hits	55
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PB1_HUMAN
NC score	0.060086 (rank : 98)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	247	Target Neighborhood Hits	261	Shared Neighborhood Hits	11
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BRD3_MOUSE
NC score	0.059925 (rank : 99)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	247	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CCD55_MOUSE
NC score	0.059523 (rank : 100)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	247	Target Neighborhood Hits	519	Shared Neighborhood Hits	92
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

OXR1_MOUSE
NC score	0.057741 (rank : 101)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	247	Target Neighborhood Hits	516	Shared Neighborhood Hits	74
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

BRD3_HUMAN
NC score	0.057550 (rank : 102)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	247	Target Neighborhood Hits	369	Shared Neighborhood Hits	51
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD4_MOUSE
NC score	0.057508 (rank : 103)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	247	Target Neighborhood Hits	845	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CBX3_HUMAN
NC score	0.057222 (rank : 104)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	247	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX7_HUMAN
NC score	0.057083 (rank : 105)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	247	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

RBM25_HUMAN
NC score	0.057073 (rank : 106)	θ value	6.88961 (rank : 211)
Query Neighborhood Hits	247	Target Neighborhood Hits	682	Shared Neighborhood Hits	87
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

THOC2_HUMAN
NC score	0.057036 (rank : 107)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	247	Target Neighborhood Hits	337	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

BRD4_HUMAN
NC score	0.056785 (rank : 108)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	247	Target Neighborhood Hits	851	Shared Neighborhood Hits	80
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CI039_HUMAN
NC score	0.056749 (rank : 109)	θ value	6.88961 (rank : 200)
Query Neighborhood Hits	247	Target Neighborhood Hits	1171	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

MLL3_HUMAN
NC score	0.056369 (rank : 110)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	247	Target Neighborhood Hits	1644	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL2_HUMAN
NC score	0.056287 (rank : 111)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	247	Target Neighborhood Hits	1788	Shared Neighborhood Hits	83
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PRP40_HUMAN
NC score	0.056234 (rank : 112)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	247	Target Neighborhood Hits	442	Shared Neighborhood Hits	77
SwissProt Accessions	O75400, O43856, O75404, Q8TBQ1, Q9H782, Q9NWU9, Q9P0Q2, Q9Y5A8	Gene names	PRPF40A, FLAF1, FNBP3, HYPA
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein HYPA/FBP11) (Fas ligand-associated factor 1) (NY-REN-6 antigen).

TR150_MOUSE
NC score	0.056112 (rank : 113)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	247	Target Neighborhood Hits	468	Shared Neighborhood Hits	81
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TR150_HUMAN
NC score	0.056003 (rank : 114)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	247	Target Neighborhood Hits	313	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

RABE1_MOUSE
NC score	0.055122 (rank : 115)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	247	Target Neighborhood Hits	1105	Shared Neighborhood Hits	112
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

BRD1_HUMAN
NC score	0.054974 (rank : 116)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	247	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

UHRF2_HUMAN
NC score	0.054366 (rank : 117)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	247	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

CP250_MOUSE
NC score	0.054266 (rank : 118)	θ value	0.00298849 (rank : 38)
Query Neighborhood Hits	247	Target Neighborhood Hits	1583	Shared Neighborhood Hits	121
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

RAD50_MOUSE
NC score	0.054195 (rank : 119)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	247	Target Neighborhood Hits	1366	Shared Neighborhood Hits	125
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

DPF1_HUMAN
NC score	0.053812 (rank : 120)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	247	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

SMC1A_MOUSE
NC score	0.053409 (rank : 121)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	247	Target Neighborhood Hits	1384	Shared Neighborhood Hits	130
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

PHF14_MOUSE
NC score	0.053016 (rank : 122)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	247	Target Neighborhood Hits	342	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PPIG_HUMAN
NC score	0.052903 (rank : 123)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	247	Target Neighborhood Hits	670	Shared Neighborhood Hits	109
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CP250_HUMAN
NC score	0.052802 (rank : 124)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	247	Target Neighborhood Hits	1805	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NFH_MOUSE
NC score	0.052616 (rank : 125)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	247	Target Neighborhood Hits	2247	Shared Neighborhood Hits	149
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAP1A_HUMAN
NC score	0.052300 (rank : 126)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	247	Target Neighborhood Hits	1626	Shared Neighborhood Hits	142
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

IF2P_HUMAN
NC score	0.052277 (rank : 127)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	247	Target Neighborhood Hits	889	Shared Neighborhood Hits	93
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CF010_HUMAN
NC score	0.052230 (rank : 128)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	247	Target Neighborhood Hits	329	Shared Neighborhood Hits	67
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

MY18A_HUMAN
NC score	0.052205 (rank : 129)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	247	Target Neighborhood Hits	1929	Shared Neighborhood Hits	152
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CYLC1_HUMAN
NC score	0.052107 (rank : 130)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	247	Target Neighborhood Hits	408	Shared Neighborhood Hits	53
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CCD55_HUMAN
NC score	0.052078 (rank : 131)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	247	Target Neighborhood Hits	513	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

OPTN_MOUSE
NC score	0.052061 (rank : 132)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	247	Target Neighborhood Hits	1120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CJ012_HUMAN
NC score	0.051916 (rank : 133)	θ value	6.88961 (rank : 201)
Query Neighborhood Hits	247	Target Neighborhood Hits	467	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

RB6I2_HUMAN
NC score	0.051892 (rank : 134)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	247	Target Neighborhood Hits	1584	Shared Neighborhood Hits	132
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

BRPF3_HUMAN
NC score	0.051826 (rank : 135)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	247	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

C8AP2_HUMAN
NC score	0.051796 (rank : 136)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	247	Target Neighborhood Hits	548	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

YTDC1_HUMAN
NC score	0.051729 (rank : 137)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	247	Target Neighborhood Hits	458	Shared Neighborhood Hits	76
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

MLL3_MOUSE
NC score	0.051604 (rank : 138)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	247	Target Neighborhood Hits	1399	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SMC2_HUMAN
NC score	0.051389 (rank : 139)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	247	Target Neighborhood Hits	1405	Shared Neighborhood Hits	133
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

NKTR_MOUSE
NC score	0.051299 (rank : 140)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	247	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PHF10_HUMAN
NC score	0.051111 (rank : 141)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	247	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

RABE1_HUMAN
NC score	0.051052 (rank : 142)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	247	Target Neighborhood Hits	1104	Shared Neighborhood Hits	111
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

ZC313_HUMAN
NC score	0.051039 (rank : 143)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	247	Target Neighborhood Hits	772	Shared Neighborhood Hits	100
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CP135_MOUSE
NC score	0.050766 (rank : 144)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	247	Target Neighborhood Hits	1278	Shared Neighborhood Hits	116
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

SM1L2_HUMAN
NC score	0.050744 (rank : 145)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	247	Target Neighborhood Hits	1019	Shared Neighborhood Hits	115
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

GOGB1_HUMAN
NC score	0.050641 (rank : 146)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	247	Target Neighborhood Hits	2297	Shared Neighborhood Hits	156
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BRPF1_HUMAN
NC score	0.050415 (rank : 147)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	247	Target Neighborhood Hits	259	Shared Neighborhood Hits	30
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

UHRF1_HUMAN
NC score	0.050326 (rank : 148)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	247	Target Neighborhood Hits	272	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

SEMG2_HUMAN
NC score	0.050270 (rank : 149)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	247	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

KMHN1_MOUSE
NC score	0.050098 (rank : 150)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	247	Target Neighborhood Hits	949	Shared Neighborhood Hits	109
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

UHRF2_MOUSE
NC score	0.050070 (rank : 151)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	247	Target Neighborhood Hits	275	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

SMC4_HUMAN
NC score	0.049187 (rank : 152)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	247	Target Neighborhood Hits	937	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

ESCO1_HUMAN
NC score	0.048997 (rank : 153)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	247	Target Neighborhood Hits	361	Shared Neighborhood Hits	76
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

RRBP1_HUMAN
NC score	0.048931 (rank : 154)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	247	Target Neighborhood Hits	1306	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

NOLC1_HUMAN
NC score	0.048694 (rank : 155)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	247	Target Neighborhood Hits	452	Shared Neighborhood Hits	36
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SYCP1_MOUSE
NC score	0.048571 (rank : 156)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	247	Target Neighborhood Hits	1456	Shared Neighborhood Hits	135
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CROCC_MOUSE
NC score	0.048523 (rank : 157)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	247	Target Neighborhood Hits	1460	Shared Neighborhood Hits	120
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RAD50_HUMAN
NC score	0.048251 (rank : 158)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	247	Target Neighborhood Hits	1317	Shared Neighborhood Hits	113
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MY18A_MOUSE
NC score	0.048234 (rank : 159)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	247	Target Neighborhood Hits	1989	Shared Neighborhood Hits	152
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

IFT81_MOUSE
NC score	0.047657 (rank : 160)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	247	Target Neighborhood Hits	959	Shared Neighborhood Hits	106
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

PININ_HUMAN
NC score	0.047056 (rank : 161)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	247	Target Neighborhood Hits	753	Shared Neighborhood Hits	94
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CROCC_HUMAN
NC score	0.046980 (rank : 162)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	247	Target Neighborhood Hits	1409	Shared Neighborhood Hits	111
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DMP1_HUMAN
NC score	0.046876 (rank : 163)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	247	Target Neighborhood Hits	491	Shared Neighborhood Hits	62
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TPR_HUMAN
NC score	0.046826 (rank : 164)	θ value	6.88961 (rank : 213)
Query Neighborhood Hits	247	Target Neighborhood Hits	1921	Shared Neighborhood Hits	137
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SMC4_MOUSE
NC score	0.046581 (rank : 165)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	247	Target Neighborhood Hits	830	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CAF1A_MOUSE
NC score	0.046419 (rank : 166)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	247	Target Neighborhood Hits	736	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

EEA1_MOUSE
NC score	0.046164 (rank : 167)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	247	Target Neighborhood Hits	1637	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

SMC3_MOUSE
NC score	0.045937 (rank : 168)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	247	Target Neighborhood Hits	1187	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

GOGA4_HUMAN
NC score	0.045831 (rank : 169)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	247	Target Neighborhood Hits	2034	Shared Neighborhood Hits	142
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

SMC3_HUMAN
NC score	0.045543 (rank : 170)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	247	Target Neighborhood Hits	1186	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

MYH11_HUMAN
NC score	0.044812 (rank : 171)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	247	Target Neighborhood Hits	1806	Shared Neighborhood Hits	137
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CN145_HUMAN
NC score	0.044437 (rank : 172)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	247	Target Neighborhood Hits	1196	Shared Neighborhood Hits	118
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

GCC2_HUMAN
NC score	0.044338 (rank : 173)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	247	Target Neighborhood Hits	1558	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.044328 (rank : 174)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	247	Target Neighborhood Hits	1559	Shared Neighborhood Hits	117
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

LZTS1_MOUSE
NC score	0.044189 (rank : 175)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	247	Target Neighborhood Hits	540	Shared Neighborhood Hits	68
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CN145_MOUSE
NC score	0.043919 (rank : 176)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	247	Target Neighborhood Hits	916	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

EEA1_HUMAN
NC score	0.043697 (rank : 177)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	247	Target Neighborhood Hits	1796	Shared Neighborhood Hits	127
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

PCLO_MOUSE
NC score	0.043682 (rank : 178)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	247	Target Neighborhood Hits	2275	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

GOGA1_MOUSE
NC score	0.043175 (rank : 179)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	247	Target Neighborhood Hits	994	Shared Neighborhood Hits	97
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CIR_HUMAN
NC score	0.042795 (rank : 180)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	247	Target Neighborhood Hits	249	Shared Neighborhood Hits	48
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

OXR1_HUMAN
NC score	0.042474 (rank : 181)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	247	Target Neighborhood Hits	282	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

SFR12_HUMAN
NC score	0.042398 (rank : 182)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	247	Target Neighborhood Hits	553	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

NOP14_MOUSE
NC score	0.042374 (rank : 183)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	247	Target Neighborhood Hits	324	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NIN_HUMAN
NC score	0.042173 (rank : 184)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	247	Target Neighborhood Hits	1416	Shared Neighborhood Hits	112
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CAF1A_HUMAN
NC score	0.041795 (rank : 185)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	247	Target Neighborhood Hits	750	Shared Neighborhood Hits	80
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

SKIL_MOUSE
NC score	0.041782 (rank : 186)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	247	Target Neighborhood Hits	719	Shared Neighborhood Hits	87
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CING_HUMAN
NC score	0.041456 (rank : 187)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	247	Target Neighborhood Hits	1275	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

ADDB_MOUSE
NC score	0.041398 (rank : 188)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	247	Target Neighborhood Hits	574	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

MYH11_MOUSE
NC score	0.041388 (rank : 189)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	247	Target Neighborhood Hits	1777	Shared Neighborhood Hits	130
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

REST_MOUSE
NC score	0.041162 (rank : 190)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	247	Target Neighborhood Hits	1506	Shared Neighborhood Hits	121
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

GOGA3_HUMAN
NC score	0.041103 (rank : 191)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	247	Target Neighborhood Hits	1317	Shared Neighborhood Hits	109
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HMMR_MOUSE
NC score	0.040924 (rank : 192)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	247	Target Neighborhood Hits	1178	Shared Neighborhood Hits	112
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MAP1B_HUMAN
NC score	0.040888 (rank : 193)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	247	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

LZTS1_HUMAN
NC score	0.040809 (rank : 194)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	247	Target Neighborhood Hits	532	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

GOGA2_MOUSE
NC score	0.040352 (rank : 195)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	247	Target Neighborhood Hits	944	Shared Neighborhood Hits	83
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

PCNT_HUMAN
NC score	0.039668 (rank : 196)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	247	Target Neighborhood Hits	1551	Shared Neighborhood Hits	117
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ARS2_HUMAN
NC score	0.039494 (rank : 197)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	247	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXP5, O95808, Q9BWP6, Q9BXP4	Gene names	ARS2, ASR2
Domain Architecture
Description	Arsenite-resistance protein 2.

EP15R_HUMAN
NC score	0.039449 (rank : 198)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	247	Target Neighborhood Hits	1083	Shared Neighborhood Hits	109
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

GOGA2_HUMAN
NC score	0.039406 (rank : 199)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	247	Target Neighborhood Hits	856	Shared Neighborhood Hits	76
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

NUMA1_HUMAN
NC score	0.039303 (rank : 200)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	247	Target Neighborhood Hits	1523	Shared Neighborhood Hits	113
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

EP15R_MOUSE
NC score	0.039074 (rank : 201)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	247	Target Neighborhood Hits	1135	Shared Neighborhood Hits	110
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

NALP5_MOUSE
NC score	0.038932 (rank : 202)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	247	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

FYCO1_HUMAN
NC score	0.038702 (rank : 203)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	247	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

MIA2_MOUSE
NC score	0.037913 (rank : 204)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	247	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

KTN1_HUMAN
NC score	0.037507 (rank : 205)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	247	Target Neighborhood Hits	1197	Shared Neighborhood Hits	101
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CTR9_MOUSE
NC score	0.037356 (rank : 206)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	247	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

HOOK3_MOUSE
NC score	0.037230 (rank : 207)	θ value	8.99809 (rank : 224)
Query Neighborhood Hits	247	Target Neighborhood Hits	1007	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MYH13_HUMAN
NC score	0.037113 (rank : 208)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	247	Target Neighborhood Hits	1504	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

HOOK3_HUMAN
NC score	0.036720 (rank : 209)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	247	Target Neighborhood Hits	1070	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MYH9_MOUSE
NC score	0.036175 (rank : 210)	θ value	6.88961 (rank : 209)
Query Neighborhood Hits	247	Target Neighborhood Hits	1829	Shared Neighborhood Hits	128
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KI21A_HUMAN
NC score	0.036156 (rank : 211)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	247	Target Neighborhood Hits	1543	Shared Neighborhood Hits	127
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

GPTC8_HUMAN
NC score	0.036053 (rank : 212)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	247	Target Neighborhood Hits	366	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

CCD11_HUMAN
NC score	0.035841 (rank : 213)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	247	Target Neighborhood Hits	822	Shared Neighborhood Hits	100
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

TOP1_HUMAN
NC score	0.035278 (rank : 214)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	247	Target Neighborhood Hits	207	Shared Neighborhood Hits	42
SwissProt Accessions	P11387, O43256, Q12855, Q12856, Q15610, Q5TFY3, Q9UJN0	Gene names	TOP1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

ARS2_MOUSE
NC score	0.035262 (rank : 215)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	247	Target Neighborhood Hits	212	Shared Neighborhood Hits	33
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

HDAC5_MOUSE
NC score	0.035251 (rank : 216)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	247	Target Neighborhood Hits	310	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

UACA_HUMAN
NC score	0.035017 (rank : 217)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	247	Target Neighborhood Hits	1622	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

PEPL_HUMAN
NC score	0.035006 (rank : 218)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	247	Target Neighborhood Hits	1141	Shared Neighborhood Hits	107
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SNIP1_HUMAN
NC score	0.034717 (rank : 219)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	247	Target Neighborhood Hits	80	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TAD8, Q96SP9, Q9H9T7	Gene names	SNIP1
Domain Architecture
Description	Smad nuclear-interacting protein 1.

HDAC5_HUMAN
NC score	0.034556 (rank : 220)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	247	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQL6, O60340, O60528, Q96DY4	Gene names	HDAC5, KIAA0600
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Antigen NY-CO-9).

CASC3_HUMAN
NC score	0.034265 (rank : 221)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	247	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	O15234	Gene names	CASC3, MLN51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node protein 51) (Protein MLN 51) (Protein barentsz) (Btz).

EP15_MOUSE
NC score	0.034263 (rank : 222)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	247	Target Neighborhood Hits	820	Shared Neighborhood Hits	79
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ZN291_HUMAN
NC score	0.033221 (rank : 223)	θ value	6.88961 (rank : 214)
Query Neighborhood Hits	247	Target Neighborhood Hits	647	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

FA44A_HUMAN
NC score	0.033009 (rank : 224)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	247	Target Neighborhood Hits	280	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MYH14_MOUSE
NC score	0.032774 (rank : 225)	θ value	0.21417 (rank : 62)
Query Neighborhood Hits	247	Target Neighborhood Hits	1225	Shared Neighborhood Hits	101
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CR034_HUMAN
NC score	0.032444 (rank : 226)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	247	Target Neighborhood Hits	538	Shared Neighborhood Hits	69
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

SYNE1_HUMAN
NC score	0.031746 (rank : 227)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	247	Target Neighborhood Hits	1484	Shared Neighborhood Hits	106
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TEX9_MOUSE
NC score	0.031732 (rank : 228)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	247	Target Neighborhood Hits	581	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

GRAP1_HUMAN
NC score	0.031594 (rank : 229)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	247	Target Neighborhood Hits	944	Shared Neighborhood Hits	91
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

ANR12_HUMAN
NC score	0.031359 (rank : 230)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	247	Target Neighborhood Hits	1081	Shared Neighborhood Hits	129
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

HDAC9_MOUSE
NC score	0.031280 (rank : 231)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	247	Target Neighborhood Hits	186	Shared Neighborhood Hits	31
SwissProt Accessions	Q99N13, Q9EPT2	Gene names	Hdac9, Hdac7b, Hdrp, Mitr
Domain Architecture	No domain graphic available
Description	Histone deacetylase 9 (HD9) (HD7B) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR).

PLCB4_HUMAN
NC score	0.030778 (rank : 232)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	247	Target Neighborhood Hits	658	Shared Neighborhood Hits	88
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

RASF8_HUMAN
NC score	0.029908 (rank : 233)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	247	Target Neighborhood Hits	469	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NHQ8, O95647, Q5SCI2, Q76KB6	Gene names	RASSF8, C12orf2
Domain Architecture
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1).

LYAR_MOUSE
NC score	0.029811 (rank : 234)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	247	Target Neighborhood Hits	153	Shared Neighborhood Hits	26
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CASC3_MOUSE
NC score	0.029746 (rank : 235)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	247	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

HDAC4_HUMAN
NC score	0.029298 (rank : 236)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	247	Target Neighborhood Hits	390	Shared Neighborhood Hits	46
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

MMTA2_HUMAN
NC score	0.028528 (rank : 237)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	247	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BU76, Q6P5Y0, Q6ZTZ6, Q6ZWA6, Q8IZH3	Gene names	MMTAG2, C1orf35
Domain Architecture	No domain graphic available
Description	Multiple myeloma tumor-associated protein 2 (hMMTAG2).

ZCHC7_HUMAN
NC score	0.028156 (rank : 238)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	247	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

DDX3Y_MOUSE
NC score	0.027727 (rank : 239)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	247	Target Neighborhood Hits	126	Shared Neighborhood Hits	17
SwissProt Accessions	Q62095, Q9QWS9	Gene names	Ddx3y, D1Pas1-rs1, Dead2
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX3Y (EC 3.6.1.-) (DEAD box protein 3, Y- chromosomal) (DEAD-box RNA helicase DEAD2) (mDEAD2) (D1Pas1-related sequence 1).

RSRC1_MOUSE
NC score	0.026551 (rank : 240)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	247	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

TF3C3_HUMAN
NC score	0.026248 (rank : 241)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	247	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

SPAT7_MOUSE
NC score	0.025844 (rank : 242)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	247	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VP2, Q8BK23	Gene names	Spata7
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 homolog.

TCOF_HUMAN
NC score	0.025121 (rank : 243)	θ value	6.88961 (rank : 212)
Query Neighborhood Hits	247	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

P85B_HUMAN
NC score	0.024549 (rank : 244)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	247	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

IF4G3_MOUSE
NC score	0.024470 (rank : 245)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	247	Target Neighborhood Hits	279	Shared Neighborhood Hits	27
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

RAI14_HUMAN
NC score	0.023208 (rank : 246)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	247	Target Neighborhood Hits	1367	Shared Neighborhood Hits	95
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RSRC1_HUMAN
NC score	0.022998 (rank : 247)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	247	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	Q96IZ7, Q96QK2, Q9NZE5	Gene names	RSRC1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

SFRS4_MOUSE
NC score	0.022492 (rank : 248)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	247	Target Neighborhood Hits	406	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TRAF3_MOUSE
NC score	0.022259 (rank : 249)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	247	Target Neighborhood Hits	476	Shared Neighborhood Hits	61
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

AP3D1_HUMAN
NC score	0.022093 (rank : 250)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	247	Target Neighborhood Hits	254	Shared Neighborhood Hits	30
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

SPTA1_MOUSE
NC score	0.022088 (rank : 251)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	247	Target Neighborhood Hits	675	Shared Neighborhood Hits	73
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TRAF3_HUMAN
NC score	0.021949 (rank : 252)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	247	Target Neighborhood Hits	463	Shared Neighborhood Hits	58
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

CS007_HUMAN
NC score	0.021934 (rank : 253)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	247	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

AP3B2_MOUSE
NC score	0.021800 (rank : 254)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	247	Target Neighborhood Hits	246	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

MOES_HUMAN
NC score	0.021360 (rank : 255)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	247	Target Neighborhood Hits	892	Shared Neighborhood Hits	86
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CNGA1_MOUSE
NC score	0.021242 (rank : 256)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	247	Target Neighborhood Hits	198	Shared Neighborhood Hits	28
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

NIP30_MOUSE
NC score	0.021095 (rank : 257)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	16
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

S25BP_MOUSE
NC score	0.021012 (rank : 258)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	247	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z266, Q3U8V4, Q922V7	Gene names	Snapap, Snap25bp
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

S25BP_HUMAN
NC score	0.021010 (rank : 259)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	247	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	O95295	Gene names	SNAPAP, SNAP25BP
Domain Architecture	No domain graphic available
Description	SNARE-associated protein Snapin (Synaptosomal-associated protein 25- binding protein) (SNAP-associated protein).

SPTA1_HUMAN
NC score	0.020808 (rank : 260)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	247	Target Neighborhood Hits	748	Shared Neighborhood Hits	70
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

DDX25_MOUSE
NC score	0.020706 (rank : 261)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	247	Target Neighborhood Hits	98	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

FIP1_HUMAN
NC score	0.019672 (rank : 262)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	247	Target Neighborhood Hits	118	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UN15, Q499Y4, Q49AU3, Q7Z608, Q8WVN3, Q96F80, Q9H077	Gene names	FIP1L1, FIP1, RHE
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1) (Factor interacting with PAP) (hFip1) (Rearranged in hypereosinophilia).

ROCK2_MOUSE
NC score	0.019569 (rank : 263)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	247	Target Neighborhood Hits	2072	Shared Neighborhood Hits	123
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

P85A_HUMAN
NC score	0.019518 (rank : 264)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	247	Target Neighborhood Hits	479	Shared Neighborhood Hits	41
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

UN84A_HUMAN
NC score	0.019464 (rank : 265)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	41
SwissProt Accessions	O94901, Q96CZ7, Q9HA14, Q9UH98	Gene names	UNC84A, KIAA0810, SUN1
Domain Architecture	No domain graphic available
Description	Sad1/unc-84 protein-like 1 (Unc-84 homolog A).

FIP1_MOUSE
NC score	0.018919 (rank : 266)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	247	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

ANGP2_MOUSE
NC score	0.018905 (rank : 267)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	247	Target Neighborhood Hits	397	Shared Neighborhood Hits	61
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

NMDE1_HUMAN
NC score	0.018892 (rank : 268)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	247	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

TOPRS_HUMAN
NC score	0.018716 (rank : 269)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	247	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

NIP30_HUMAN
NC score	0.018666 (rank : 270)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	247	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZU8	Gene names	NIP30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

HPS1_MOUSE
NC score	0.018445 (rank : 271)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	247	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	O08983, O35155, O35725, O35950	Gene names	Hps1, Ep, Hps
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 1 protein homolog.

WDR60_HUMAN
NC score	0.018398 (rank : 272)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	247	Target Neighborhood Hits	286	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WVS4, Q9NW58	Gene names	WDR60
Domain Architecture	No domain graphic available
Description	WD repeat protein 60.

PALM_MOUSE
NC score	0.018280 (rank : 273)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	247	Target Neighborhood Hits	228	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

KIF11_HUMAN
NC score	0.018214 (rank : 274)	θ value	8.99809 (rank : 230)
Query Neighborhood Hits	247	Target Neighborhood Hits	583	Shared Neighborhood Hits	69
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

P85A_MOUSE
NC score	0.018025 (rank : 275)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	247	Target Neighborhood Hits	435	Shared Neighborhood Hits	32
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

ANGP2_HUMAN
NC score	0.017864 (rank : 276)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	247	Target Neighborhood Hits	400	Shared Neighborhood Hits	60
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

DPOLZ_HUMAN
NC score	0.017379 (rank : 277)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	247	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

ITSN2_HUMAN
NC score	0.017379 (rank : 278)	θ value	8.99809 (rank : 227)
Query Neighborhood Hits	247	Target Neighborhood Hits	1173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ROCK2_HUMAN
NC score	0.017078 (rank : 279)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	247	Target Neighborhood Hits	2073	Shared Neighborhood Hits	128
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CS007_MOUSE
NC score	0.016974 (rank : 280)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	247	Target Neighborhood Hits	464	Shared Neighborhood Hits	28
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

BAP31_HUMAN
NC score	0.016719 (rank : 281)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	247	Target Neighborhood Hits	257	Shared Neighborhood Hits	39
SwissProt Accessions	P51572, Q13836, Q96CF0	Gene names	BCAP31, BAP31, DXS1357E
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31) (Protein CDM) (6C6-AG tumor-associated antigen).

UBP42_HUMAN
NC score	0.016459 (rank : 282)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	247	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

NMDE1_MOUSE
NC score	0.016183 (rank : 283)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	247	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

JARD2_MOUSE
NC score	0.014268 (rank : 284)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	247	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

PRP4B_MOUSE
NC score	0.013888 (rank : 285)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	247	Target Neighborhood Hits	1040	Shared Neighborhood Hits	54
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

CNGB3_HUMAN
NC score	0.013188 (rank : 286)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

PLCB3_MOUSE
NC score	0.013167 (rank : 287)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	247	Target Neighborhood Hits	344	Shared Neighborhood Hits	46
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

CNGA1_HUMAN
NC score	0.013131 (rank : 288)	θ value	6.88961 (rank : 202)
Query Neighborhood Hits	247	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

ERCC5_MOUSE
NC score	0.012595 (rank : 289)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	247	Target Neighborhood Hits	206	Shared Neighborhood Hits	18
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

PRP4B_HUMAN
NC score	0.012364 (rank : 290)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	247	Target Neighborhood Hits	1030	Shared Neighborhood Hits	55
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MKL2_MOUSE
NC score	0.011822 (rank : 291)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	247	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

GTSE1_HUMAN
NC score	0.011802 (rank : 292)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	247	Target Neighborhood Hits	193	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

RGS12_HUMAN
NC score	0.010778 (rank : 293)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	247	Target Neighborhood Hits	333	Shared Neighborhood Hits	11
SwissProt Accessions	O14924, O14922, O14923, O43510, O75338	Gene names	RGS12
Domain Architecture
Description	Regulator of G-protein signaling 12 (RGS12).

PAHX_HUMAN
NC score	0.010693 (rank : 294)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	247	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	O14832	Gene names	PHYH, PAHX
Domain Architecture
Description	Phytanoyl-CoA dioxygenase, peroxisomal precursor (EC 1.14.11.18) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) (Phytanic acid oxidase).

DJBP_MOUSE
NC score	0.010309 (rank : 295)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	247	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

ANXA3_MOUSE
NC score	0.010143 (rank : 296)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	247	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	O35639	Gene names	Anxa3, Anx3
Domain Architecture
Description	Annexin A3 (Annexin III) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) (35-alpha calcimedin).

PENK_HUMAN
NC score	0.010095 (rank : 297)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	247	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PENK_MOUSE
NC score	0.009910 (rank : 298)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	247	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

APBA1_HUMAN
NC score	0.009651 (rank : 299)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	247	Target Neighborhood Hits	325	Shared Neighborhood Hits	15
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CD2L2_HUMAN
NC score	0.009434 (rank : 300)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	247	Target Neighborhood Hits	1439	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

WWP2_MOUSE
NC score	0.008803 (rank : 301)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	247	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DBH0, Q8BTG4, Q923F6	Gene names	Wwp2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2).

CD2L1_MOUSE
NC score	0.008715 (rank : 302)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	247	Target Neighborhood Hits	1463	Shared Neighborhood Hits	89
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

K2C7_HUMAN
NC score	0.008699 (rank : 303)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	247	Target Neighborhood Hits	369	Shared Neighborhood Hits	59
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

ANXA3_HUMAN
NC score	0.008634 (rank : 304)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	247	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P12429, Q6LET2	Gene names	ANXA3, ANX3
Domain Architecture
Description	Annexin A3 (Annexin III) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III) (35-alpha calcimedin) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase).

IF4A1_HUMAN
NC score	0.008488 (rank : 305)	θ value	8.99809 (rank : 225)
Query Neighborhood Hits	247	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.008488 (rank : 306)	θ value	8.99809 (rank : 226)
Query Neighborhood Hits	247	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

SYTL1_MOUSE
NC score	0.007785 (rank : 307)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	247	Target Neighborhood Hits	314	Shared Neighborhood Hits	18
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

K1958_HUMAN
NC score	0.007757 (rank : 308)	θ value	8.99809 (rank : 229)
Query Neighborhood Hits	247	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

DLG7_MOUSE
NC score	0.007611 (rank : 309)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	247	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4R9, Q6ZQL3, Q80VS7, Q8BUC8, Q8BZ79	Gene names	Dlg7, Kiaa0008
Domain Architecture	No domain graphic available
Description	Discs large homolog 7 (Hepatoma up-regulated protein homolog) (HURP).

MBD6_HUMAN
NC score	0.007449 (rank : 310)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	247	Target Neighborhood Hits	349	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CD2L1_HUMAN
NC score	0.007093 (rank : 311)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	247	Target Neighborhood Hits	1467	Shared Neighborhood Hits	83
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

K0562_MOUSE
NC score	0.006725 (rank : 312)	θ value	8.99809 (rank : 228)
Query Neighborhood Hits	247	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

KTNA1_HUMAN
NC score	0.004944 (rank : 313)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	247	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

TNIK_HUMAN
NC score	0.003447 (rank : 314)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	247	Target Neighborhood Hits	1570	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

HERC2_HUMAN
NC score	0.002990 (rank : 315)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	247	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

GSK3A_HUMAN
NC score	0.002712 (rank : 316)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	247	Target Neighborhood Hits	835	Shared Neighborhood Hits	15
SwissProt Accessions	P49840, O14959	Gene names	GSK3A
Domain Architecture
Description	Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

GSK3B_MOUSE
NC score	0.002683 (rank : 317)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	247	Target Neighborhood Hits	800	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV60	Gene names	Gsk3b
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

GSK3B_HUMAN
NC score	0.002682 (rank : 318)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	247	Target Neighborhood Hits	801	Shared Neighborhood Hits	15
SwissProt Accessions	P49841, Q9BWH3, Q9UL47	Gene names	GSK3B
Domain Architecture
Description	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta).

SEZ6L_HUMAN
NC score	0.002110 (rank : 319)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	247	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CDKL3_MOUSE
NC score	-0.000083 (rank : 320)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	247	Target Neighborhood Hits	857	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

E2AK4_MOUSE
NC score	-0.000283 (rank : 321)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	247	Target Neighborhood Hits	984	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

RREB1_HUMAN
NC score	-0.001559 (rank : 322)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	247	Target Neighborhood Hits	879	Shared Neighborhood Hits	20
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

CNTN6_MOUSE
NC score	-0.001783 (rank : 323)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	247	Target Neighborhood Hits	429	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

RIPK4_HUMAN
NC score	-0.003889 (rank : 324)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	247	Target Neighborhood Hits	1094	Shared Neighborhood Hits	18
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).