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Network neighborhood for query Sequence : SMRA3_MOUSE

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SMRA3_MOUSE
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMRA3_HUMAN
θ value	0 (rank : 1)	NC score	0.991223 (rank : 2)
Query Neighborhood Hits	267	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	267
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TTF2_HUMAN
θ value	4.84666e-62 (rank : 3)	NC score	0.813398 (rank : 3)
Query Neighborhood Hits	267	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TTF2_MOUSE
θ value	1.98146e-39 (rank : 4)	NC score	0.755883 (rank : 6)
Query Neighborhood Hits	267	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMRCD_MOUSE
θ value	3.4976e-36 (rank : 5)	NC score	0.768519 (rank : 4)
Query Neighborhood Hits	267	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
θ value	7.29293e-34 (rank : 6)	NC score	0.767395 (rank : 5)
Query Neighborhood Hits	267	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CHD2_HUMAN
θ value	5.42112e-21 (rank : 7)	NC score	0.707206 (rank : 19)
Query Neighborhood Hits	267	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

RAD54_HUMAN
θ value	2.06002e-20 (rank : 8)	NC score	0.737243 (rank : 9)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RA54B_HUMAN
θ value	2.69047e-20 (rank : 9)	NC score	0.739791 (rank : 7)
Query Neighborhood Hits	267	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD4_HUMAN
θ value	7.82807e-20 (rank : 10)	NC score	0.656977 (rank : 29)
Query Neighborhood Hits	267	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	7.82807e-20 (rank : 11)	NC score	0.654579 (rank : 32)
Query Neighborhood Hits	267	Target Neighborhood Hits	408	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	7.82807e-20 (rank : 12)	NC score	0.655977 (rank : 30)
Query Neighborhood Hits	267	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

SMCA4_HUMAN
θ value	7.82807e-20 (rank : 13)	NC score	0.678232 (rank : 27)
Query Neighborhood Hits	267	Target Neighborhood Hits	597	Shared Neighborhood Hits	44
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

CHD3_HUMAN
θ value	1.74391e-19 (rank : 14)	NC score	0.655876 (rank : 31)
Query Neighborhood Hits	267	Target Neighborhood Hits	397	Shared Neighborhood Hits	50
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

SMCA1_HUMAN
θ value	1.74391e-19 (rank : 15)	NC score	0.723678 (rank : 13)
Query Neighborhood Hits	267	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	1.74391e-19 (rank : 16)	NC score	0.722299 (rank : 14)
Query Neighborhood Hits	267	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

RAD54_MOUSE
θ value	2.97466e-19 (rank : 17)	NC score	0.734070 (rank : 11)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

BTAF1_HUMAN
θ value	3.88503e-19 (rank : 18)	NC score	0.738742 (rank : 8)
Query Neighborhood Hits	267	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

SMCA2_HUMAN
θ value	3.88503e-19 (rank : 19)	NC score	0.687818 (rank : 26)
Query Neighborhood Hits	267	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

INOC1_MOUSE
θ value	1.13037e-18 (rank : 20)	NC score	0.714470 (rank : 18)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
θ value	2.5182e-18 (rank : 21)	NC score	0.714698 (rank : 17)
Query Neighborhood Hits	267	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

CHD1_MOUSE
θ value	4.29542e-18 (rank : 22)	NC score	0.704520 (rank : 20)
Query Neighborhood Hits	267	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RA54B_MOUSE
θ value	4.29542e-18 (rank : 23)	NC score	0.735611 (rank : 10)
Query Neighborhood Hits	267	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD1_HUMAN
θ value	7.32683e-18 (rank : 24)	NC score	0.700757 (rank : 22)
Query Neighborhood Hits	267	Target Neighborhood Hits	337	Shared Neighborhood Hits	40
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
θ value	7.32683e-18 (rank : 25)	NC score	0.698261 (rank : 23)
Query Neighborhood Hits	267	Target Neighborhood Hits	342	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	9.56915e-18 (rank : 26)	NC score	0.704202 (rank : 21)
Query Neighborhood Hits	267	Target Neighborhood Hits	235	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

ERCC6_HUMAN
θ value	9.56915e-18 (rank : 27)	NC score	0.727769 (rank : 12)
Query Neighborhood Hits	267	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA5_HUMAN
θ value	1.63225e-17 (rank : 28)	NC score	0.721370 (rank : 16)
Query Neighborhood Hits	267	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	1.63225e-17 (rank : 29)	NC score	0.721470 (rank : 15)
Query Neighborhood Hits	267	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

CHD9_HUMAN
θ value	4.74913e-17 (rank : 30)	NC score	0.692313 (rank : 24)
Query Neighborhood Hits	267	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	6.20254e-17 (rank : 31)	NC score	0.688529 (rank : 25)
Query Neighborhood Hits	267	Target Neighborhood Hits	427	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ATRX_HUMAN
θ value	3.52202e-12 (rank : 32)	NC score	0.548804 (rank : 37)
Query Neighborhood Hits	267	Target Neighborhood Hits	842	Shared Neighborhood Hits	53
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	6.00763e-12 (rank : 33)	NC score	0.564771 (rank : 36)
Query Neighborhood Hits	267	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SMAL1_MOUSE
θ value	9.59137e-10 (rank : 34)	NC score	0.661131 (rank : 28)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMAL1_HUMAN
θ value	2.79066e-09 (rank : 35)	NC score	0.650843 (rank : 33)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

EP400_HUMAN
θ value	8.11959e-09 (rank : 36)	NC score	0.612167 (rank : 34)
Query Neighborhood Hits	267	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

BRCA1_HUMAN
θ value	4.0297e-08 (rank : 37)	NC score	0.356921 (rank : 43)
Query Neighborhood Hits	267	Target Neighborhood Hits	381	Shared Neighborhood Hits	175
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	4.0297e-08 (rank : 38)	NC score	0.355417 (rank : 44)
Query Neighborhood Hits	267	Target Neighborhood Hits	436	Shared Neighborhood Hits	179
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

EP400_MOUSE
θ value	6.87365e-08 (rank : 39)	NC score	0.605038 (rank : 35)
Query Neighborhood Hits	267	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RN185_HUMAN
θ value	2.88788e-06 (rank : 40)	NC score	0.371011 (rank : 39)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	168
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI43_HUMAN
θ value	6.43352e-06 (rank : 41)	NC score	0.309984 (rank : 58)
Query Neighborhood Hits	267	Target Neighborhood Hits	341	Shared Neighborhood Hits	180
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RN185_MOUSE
θ value	8.40245e-06 (rank : 42)	NC score	0.364923 (rank : 41)
Query Neighborhood Hits	267	Target Neighborhood Hits	211	Shared Neighborhood Hits	168
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN125_MOUSE
θ value	1.09739e-05 (rank : 43)	NC score	0.373673 (rank : 38)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	176
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RO52_MOUSE
θ value	2.44474e-05 (rank : 44)	NC score	0.291527 (rank : 72)
Query Neighborhood Hits	267	Target Neighborhood Hits	360	Shared Neighborhood Hits	178
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RN125_HUMAN
θ value	3.19293e-05 (rank : 45)	NC score	0.367193 (rank : 40)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	175
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRI11_HUMAN
θ value	3.19293e-05 (rank : 46)	NC score	0.292248 (rank : 68)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	183
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	3.19293e-05 (rank : 47)	NC score	0.292288 (rank : 67)
Query Neighborhood Hits	267	Target Neighborhood Hits	329	Shared Neighborhood Hits	184
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI26_HUMAN
θ value	4.1701e-05 (rank : 48)	NC score	0.325611 (rank : 50)
Query Neighborhood Hits	267	Target Neighborhood Hits	335	Shared Neighborhood Hits	184
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI31_HUMAN
θ value	4.1701e-05 (rank : 49)	NC score	0.342179 (rank : 48)
Query Neighborhood Hits	267	Target Neighborhood Hits	299	Shared Neighborhood Hits	180
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

RNF5_HUMAN
θ value	7.1131e-05 (rank : 50)	NC score	0.349183 (rank : 46)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	159
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI26_MOUSE
θ value	7.1131e-05 (rank : 51)	NC score	0.326398 (rank : 49)
Query Neighborhood Hits	267	Target Neighborhood Hits	339	Shared Neighborhood Hits	186
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RN146_HUMAN
θ value	0.000158464 (rank : 52)	NC score	0.298208 (rank : 62)
Query Neighborhood Hits	267	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	0.000158464 (rank : 53)	NC score	0.296341 (rank : 65)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RNF5_MOUSE
θ value	0.00020696 (rank : 54)	NC score	0.343338 (rank : 47)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	157
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI39_HUMAN
θ value	0.00020696 (rank : 55)	NC score	0.287549 (rank : 79)
Query Neighborhood Hits	267	Target Neighborhood Hits	693	Shared Neighborhood Hits	194
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	0.00020696 (rank : 56)	NC score	0.287784 (rank : 78)
Query Neighborhood Hits	267	Target Neighborhood Hits	691	Shared Neighborhood Hits	193
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI50_HUMAN
θ value	0.000270298 (rank : 57)	NC score	0.299575 (rank : 60)
Query Neighborhood Hits	267	Target Neighborhood Hits	294	Shared Neighborhood Hits	188
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN168_HUMAN
θ value	0.00035302 (rank : 58)	NC score	0.320508 (rank : 51)
Query Neighborhood Hits	267	Target Neighborhood Hits	370	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN141_HUMAN
θ value	0.000461057 (rank : 59)	NC score	0.260896 (rank : 122)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	142
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.000461057 (rank : 60)	NC score	0.260069 (rank : 126)
Query Neighborhood Hits	267	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RO52_HUMAN
θ value	0.000461057 (rank : 61)	NC score	0.288089 (rank : 77)
Query Neighborhood Hits	267	Target Neighborhood Hits	419	Shared Neighborhood Hits	185
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI40_HUMAN
θ value	0.000461057 (rank : 62)	NC score	0.361635 (rank : 42)
Query Neighborhood Hits	267	Target Neighborhood Hits	279	Shared Neighborhood Hits	173
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM3_HUMAN
θ value	0.000786445 (rank : 63)	NC score	0.268715 (rank : 106)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	175
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

PEX10_HUMAN
θ value	0.00102713 (rank : 64)	NC score	0.351821 (rank : 45)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	173
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRIM3_MOUSE
θ value	0.00134147 (rank : 65)	NC score	0.266345 (rank : 111)
Query Neighborhood Hits	267	Target Neighborhood Hits	351	Shared Neighborhood Hits	173
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM6_MOUSE
θ value	0.00134147 (rank : 66)	NC score	0.287049 (rank : 81)
Query Neighborhood Hits	267	Target Neighborhood Hits	451	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

RN168_MOUSE
θ value	0.00175202 (rank : 67)	NC score	0.303230 (rank : 59)
Query Neighborhood Hits	267	Target Neighborhood Hits	440	Shared Neighborhood Hits	170
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI25_MOUSE
θ value	0.00175202 (rank : 68)	NC score	0.285518 (rank : 87)
Query Neighborhood Hits	267	Target Neighborhood Hits	446	Shared Neighborhood Hits	176
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRIM6_HUMAN
θ value	0.00175202 (rank : 69)	NC score	0.286031 (rank : 86)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	176
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI22_HUMAN
θ value	0.00228821 (rank : 70)	NC score	0.296489 (rank : 64)
Query Neighborhood Hits	267	Target Neighborhood Hits	396	Shared Neighborhood Hits	178
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRAF6_HUMAN
θ value	0.00298849 (rank : 71)	NC score	0.232548 (rank : 141)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI17_HUMAN
θ value	0.00298849 (rank : 72)	NC score	0.286034 (rank : 85)
Query Neighborhood Hits	267	Target Neighborhood Hits	318	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI32_HUMAN
θ value	0.00298849 (rank : 73)	NC score	0.280285 (rank : 91)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	137
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	0.00298849 (rank : 74)	NC score	0.279348 (rank : 92)
Query Neighborhood Hits	267	Target Neighborhood Hits	271	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
θ value	0.00298849 (rank : 75)	NC score	0.278571 (rank : 93)
Query Neighborhood Hits	267	Target Neighborhood Hits	416	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI41_HUMAN
θ value	0.00298849 (rank : 76)	NC score	0.263742 (rank : 117)
Query Neighborhood Hits	267	Target Neighborhood Hits	349	Shared Neighborhood Hits	145
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

RNF8_HUMAN
θ value	0.00390308 (rank : 77)	NC score	0.265960 (rank : 113)
Query Neighborhood Hits	267	Target Neighborhood Hits	622	Shared Neighborhood Hits	196
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI38_HUMAN
θ value	0.00390308 (rank : 78)	NC score	0.275470 (rank : 95)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	162
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI50_MOUSE
θ value	0.00390308 (rank : 79)	NC score	0.296896 (rank : 63)
Query Neighborhood Hits	267	Target Neighborhood Hits	326	Shared Neighborhood Hits	188
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI56_HUMAN
θ value	0.00390308 (rank : 80)	NC score	0.253313 (rank : 128)
Query Neighborhood Hits	267	Target Neighborhood Hits	339	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM5_HUMAN
θ value	0.00390308 (rank : 81)	NC score	0.295811 (rank : 66)
Query Neighborhood Hits	267	Target Neighborhood Hits	424	Shared Neighborhood Hits	182
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRAF6_MOUSE
θ value	0.00509761 (rank : 82)	NC score	0.237411 (rank : 137)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	155
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI60_HUMAN
θ value	0.00509761 (rank : 83)	NC score	0.289683 (rank : 76)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	183
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI73_HUMAN
θ value	0.00509761 (rank : 84)	NC score	0.316431 (rank : 52)
Query Neighborhood Hits	267	Target Neighborhood Hits	258	Shared Neighborhood Hits	176
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	0.00509761 (rank : 85)	NC score	0.314327 (rank : 55)
Query Neighborhood Hits	267	Target Neighborhood Hits	249	Shared Neighborhood Hits	171
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM2_HUMAN
θ value	0.00509761 (rank : 86)	NC score	0.267818 (rank : 107)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
θ value	0.00509761 (rank : 87)	NC score	0.267282 (rank : 108)
Query Neighborhood Hits	267	Target Neighborhood Hits	331	Shared Neighborhood Hits	176
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI12_MOUSE
θ value	0.00665767 (rank : 88)	NC score	0.315448 (rank : 54)
Query Neighborhood Hits	267	Target Neighborhood Hits	387	Shared Neighborhood Hits	173
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

R113A_HUMAN
θ value	0.00869519 (rank : 89)	NC score	0.233316 (rank : 139)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	129
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI17_MOUSE
θ value	0.00869519 (rank : 90)	NC score	0.270931 (rank : 100)
Query Neighborhood Hits	267	Target Neighborhood Hits	620	Shared Neighborhood Hits	172
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RNF8_MOUSE
θ value	0.0113563 (rank : 91)	NC score	0.277999 (rank : 94)
Query Neighborhood Hits	267	Target Neighborhood Hits	618	Shared Neighborhood Hits	198
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

NHLC1_HUMAN
θ value	0.0148317 (rank : 92)	NC score	0.169227 (rank : 176)
Query Neighborhood Hits	267	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI10_MOUSE
θ value	0.0148317 (rank : 93)	NC score	0.283245 (rank : 90)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

RAG1_HUMAN
θ value	0.0193708 (rank : 94)	NC score	0.249756 (rank : 131)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	141
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RING2_HUMAN
θ value	0.0193708 (rank : 95)	NC score	0.263779 (rank : 116)
Query Neighborhood Hits	267	Target Neighborhood Hits	201	Shared Neighborhood Hits	147
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.0193708 (rank : 96)	NC score	0.263719 (rank : 118)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

UHRF2_HUMAN
θ value	0.0193708 (rank : 97)	NC score	0.224778 (rank : 147)
Query Neighborhood Hits	267	Target Neighborhood Hits	269	Shared Neighborhood Hits	149
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ZN313_MOUSE
θ value	0.0193708 (rank : 98)	NC score	0.315962 (rank : 53)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	177
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

BFAR_MOUSE
θ value	0.0252991 (rank : 99)	NC score	0.291400 (rank : 73)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

CBL_HUMAN
θ value	0.0252991 (rank : 100)	NC score	0.167263 (rank : 178)
Query Neighborhood Hits	267	Target Neighborhood Hits	353	Shared Neighborhood Hits	144
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0252991 (rank : 101)	NC score	0.169591 (rank : 175)
Query Neighborhood Hits	267	Target Neighborhood Hits	426	Shared Neighborhood Hits	150
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

LNX2_MOUSE
θ value	0.0252991 (rank : 102)	NC score	0.164765 (rank : 180)
Query Neighborhood Hits	267	Target Neighborhood Hits	407	Shared Neighborhood Hits	163
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PCGF6_MOUSE
θ value	0.0252991 (rank : 103)	NC score	0.194708 (rank : 150)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RFWD2_MOUSE
θ value	0.0252991 (rank : 104)	NC score	0.183858 (rank : 163)
Query Neighborhood Hits	267	Target Neighborhood Hits	535	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRAF3_MOUSE
θ value	0.0252991 (rank : 105)	NC score	0.138188 (rank : 222)
Query Neighborhood Hits	267	Target Neighborhood Hits	476	Shared Neighborhood Hits	122
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI10_HUMAN
θ value	0.0252991 (rank : 106)	NC score	0.286049 (rank : 84)
Query Neighborhood Hits	267	Target Neighborhood Hits	315	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI25_HUMAN
θ value	0.0252991 (rank : 107)	NC score	0.267003 (rank : 109)
Query Neighborhood Hits	267	Target Neighborhood Hits	472	Shared Neighborhood Hits	176
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI30_MOUSE
θ value	0.0252991 (rank : 108)	NC score	0.299533 (rank : 61)
Query Neighborhood Hits	267	Target Neighborhood Hits	434	Shared Neighborhood Hits	176
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

ZN313_HUMAN
θ value	0.0252991 (rank : 109)	NC score	0.311177 (rank : 56)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

CBLC_HUMAN
θ value	0.0330416 (rank : 110)	NC score	0.175433 (rank : 170)
Query Neighborhood Hits	267	Target Neighborhood Hits	173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

LNX2_HUMAN
θ value	0.0330416 (rank : 111)	NC score	0.164970 (rank : 179)
Query Neighborhood Hits	267	Target Neighborhood Hits	389	Shared Neighborhood Hits	164
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LRSM1_MOUSE
θ value	0.0330416 (rank : 112)	NC score	0.069812 (rank : 302)
Query Neighborhood Hits	267	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

RING1_HUMAN
θ value	0.0330416 (rank : 113)	NC score	0.273751 (rank : 97)
Query Neighborhood Hits	267	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.0330416 (rank : 114)	NC score	0.270082 (rank : 101)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	149
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRAF3_HUMAN
θ value	0.0330416 (rank : 115)	NC score	0.134122 (rank : 232)
Query Neighborhood Hits	267	Target Neighborhood Hits	463	Shared Neighborhood Hits	116
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRI56_MOUSE
θ value	0.0330416 (rank : 116)	NC score	0.235327 (rank : 138)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	151
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BFAR_HUMAN
θ value	0.0431538 (rank : 117)	NC score	0.287287 (rank : 80)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

LRSM1_HUMAN
θ value	0.0431538 (rank : 118)	NC score	0.067261 (rank : 310)
Query Neighborhood Hits	267	Target Neighborhood Hits	1078	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PEX2_MOUSE
θ value	0.0431538 (rank : 119)	NC score	0.133892 (rank : 234)
Query Neighborhood Hits	267	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

PZRN3_HUMAN
θ value	0.0563607 (rank : 120)	NC score	0.153613 (rank : 199)
Query Neighborhood Hits	267	Target Neighborhood Hits	461	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	0.0563607 (rank : 121)	NC score	0.155352 (rank : 197)
Query Neighborhood Hits	267	Target Neighborhood Hits	447	Shared Neighborhood Hits	161
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TRI52_HUMAN
θ value	0.0563607 (rank : 122)	NC score	0.310116 (rank : 57)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	154
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI55_HUMAN
θ value	0.0563607 (rank : 123)	NC score	0.232654 (rank : 140)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

CBLB_HUMAN
θ value	0.0736092 (rank : 124)	NC score	0.160698 (rank : 187)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	140
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.0736092 (rank : 125)	NC score	0.159847 (rank : 188)
Query Neighborhood Hits	267	Target Neighborhood Hits	277	Shared Neighborhood Hits	139
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

R113B_HUMAN
θ value	0.0736092 (rank : 126)	NC score	0.216193 (rank : 149)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RFWD2_HUMAN
θ value	0.0736092 (rank : 127)	NC score	0.181907 (rank : 165)
Query Neighborhood Hits	267	Target Neighborhood Hits	518	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN126_HUMAN
θ value	0.0736092 (rank : 128)	NC score	0.113581 (rank : 250)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TRI13_HUMAN
θ value	0.0736092 (rank : 129)	NC score	0.292133 (rank : 69)
Query Neighborhood Hits	267	Target Neighborhood Hits	274	Shared Neighborhood Hits	173
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI60_MOUSE
θ value	0.0736092 (rank : 130)	NC score	0.269029 (rank : 104)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	0.0736092 (rank : 131)	NC score	0.264406 (rank : 115)
Query Neighborhood Hits	267	Target Neighborhood Hits	584	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	0.0736092 (rank : 132)	NC score	0.269968 (rank : 102)
Query Neighborhood Hits	267	Target Neighborhood Hits	478	Shared Neighborhood Hits	164
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RAG1_MOUSE
θ value	0.0961366 (rank : 133)	NC score	0.239893 (rank : 136)
Query Neighborhood Hits	267	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRI68_MOUSE
θ value	0.0961366 (rank : 134)	NC score	0.274687 (rank : 96)
Query Neighborhood Hits	267	Target Neighborhood Hits	356	Shared Neighborhood Hits	183
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

BIRC3_MOUSE
θ value	0.125558 (rank : 135)	NC score	0.081610 (rank : 284)
Query Neighborhood Hits	267	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

NHLC1_MOUSE
θ value	0.125558 (rank : 136)	NC score	0.171278 (rank : 174)
Query Neighborhood Hits	267	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN126_MOUSE
θ value	0.125558 (rank : 137)	NC score	0.115373 (rank : 248)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TRI13_MOUSE
θ value	0.125558 (rank : 138)	NC score	0.291714 (rank : 71)
Query Neighborhood Hits	267	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI27_HUMAN
θ value	0.125558 (rank : 139)	NC score	0.260495 (rank : 124)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	163
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	0.125558 (rank : 140)	NC score	0.257997 (rank : 127)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	158
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI63_HUMAN
θ value	0.125558 (rank : 141)	NC score	0.227358 (rank : 143)
Query Neighborhood Hits	267	Target Neighborhood Hits	298	Shared Neighborhood Hits	118
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

APC11_HUMAN
θ value	0.163984 (rank : 142)	NC score	0.080574 (rank : 285)
Query Neighborhood Hits	267	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

PCGF2_HUMAN
θ value	0.163984 (rank : 143)	NC score	0.164292 (rank : 182)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	111
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.163984 (rank : 144)	NC score	0.164351 (rank : 181)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PEX2_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.112121 (rank : 251)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

RN166_HUMAN
θ value	0.163984 (rank : 146)	NC score	0.283587 (rank : 89)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	157
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.163984 (rank : 147)	NC score	0.284513 (rank : 88)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	160
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RNF32_HUMAN
θ value	0.163984 (rank : 148)	NC score	0.133217 (rank : 235)
Query Neighborhood Hits	267	Target Neighborhood Hits	133	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

TRI63_MOUSE
θ value	0.163984 (rank : 149)	NC score	0.231745 (rank : 142)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	119
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI68_HUMAN
θ value	0.163984 (rank : 150)	NC score	0.271329 (rank : 99)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRIM8_HUMAN
θ value	0.163984 (rank : 151)	NC score	0.261355 (rank : 121)
Query Neighborhood Hits	267	Target Neighborhood Hits	650	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	0.163984 (rank : 152)	NC score	0.260515 (rank : 123)
Query Neighborhood Hits	267	Target Neighborhood Hits	674	Shared Neighborhood Hits	156
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CM007_HUMAN
θ value	0.21417 (rank : 153)	NC score	0.180224 (rank : 166)
Query Neighborhood Hits	267	Target Neighborhood Hits	422	Shared Neighborhood Hits	122
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	0.21417 (rank : 154)	NC score	0.193389 (rank : 153)
Query Neighborhood Hits	267	Target Neighborhood Hits	416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RNF41_HUMAN
θ value	0.21417 (rank : 155)	NC score	0.241660 (rank : 135)
Query Neighborhood Hits	267	Target Neighborhood Hits	226	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.21417 (rank : 156)	NC score	0.241798 (rank : 134)
Query Neighborhood Hits	267	Target Neighborhood Hits	224	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TRI35_HUMAN
θ value	0.21417 (rank : 157)	NC score	0.290990 (rank : 74)
Query Neighborhood Hits	267	Target Neighborhood Hits	382	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRIM4_HUMAN
θ value	0.21417 (rank : 158)	NC score	0.286808 (rank : 83)
Query Neighborhood Hits	267	Target Neighborhood Hits	321	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

UHRF2_MOUSE
θ value	0.21417 (rank : 159)	NC score	0.216691 (rank : 148)
Query Neighborhood Hits	267	Target Neighborhood Hits	275	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

XPO4_HUMAN
θ value	0.21417 (rank : 160)	NC score	0.058185 (rank : 336)
Query Neighborhood Hits	267	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0E2, Q5VUZ5, Q9H934	Gene names	XPO4, KIAA1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

XPO4_MOUSE
θ value	0.21417 (rank : 161)	NC score	0.058259 (rank : 335)
Query Neighborhood Hits	267	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESJ0, Q6ZPJ4	Gene names	Xpo4, Kiaa1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

I20L2_HUMAN
θ value	0.279714 (rank : 162)	NC score	0.030285 (rank : 356)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

NEUL1_HUMAN
θ value	0.279714 (rank : 163)	NC score	0.120942 (rank : 243)
Query Neighborhood Hits	267	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

PCGF6_HUMAN
θ value	0.279714 (rank : 164)	NC score	0.186324 (rank : 160)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI47_HUMAN
θ value	0.279714 (rank : 165)	NC score	0.252268 (rank : 130)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	156
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	0.279714 (rank : 166)	NC score	0.252510 (rank : 129)
Query Neighborhood Hits	267	Target Neighborhood Hits	295	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM7_MOUSE
θ value	0.279714 (rank : 167)	NC score	0.269174 (rank : 103)
Query Neighborhood Hits	267	Target Neighborhood Hits	358	Shared Neighborhood Hits	162
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

UHRF1_MOUSE
θ value	0.279714 (rank : 168)	NC score	0.183080 (rank : 164)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	138
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BIRC3_HUMAN
θ value	0.365318 (rank : 169)	NC score	0.093190 (rank : 275)
Query Neighborhood Hits	267	Target Neighborhood Hits	133	Shared Neighborhood Hits	84
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

NEURL_MOUSE
θ value	0.365318 (rank : 170)	NC score	0.118153 (rank : 245)
Query Neighborhood Hits	267	Target Neighborhood Hits	106	Shared Neighborhood Hits	61
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RNF26_HUMAN
θ value	0.365318 (rank : 171)	NC score	0.140887 (rank : 218)
Query Neighborhood Hits	267	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF39_HUMAN
θ value	0.365318 (rank : 172)	NC score	0.226538 (rank : 144)
Query Neighborhood Hits	267	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF4_HUMAN
θ value	0.365318 (rank : 173)	NC score	0.265845 (rank : 114)
Query Neighborhood Hits	267	Target Neighborhood Hits	212	Shared Neighborhood Hits	154
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.365318 (rank : 174)	NC score	0.263007 (rank : 120)
Query Neighborhood Hits	267	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRI35_MOUSE
θ value	0.365318 (rank : 175)	NC score	0.286823 (rank : 82)
Query Neighborhood Hits	267	Target Neighborhood Hits	465	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM7_HUMAN
θ value	0.365318 (rank : 176)	NC score	0.266447 (rank : 110)
Query Neighborhood Hits	267	Target Neighborhood Hits	336	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

DTX3L_HUMAN
θ value	0.47712 (rank : 177)	NC score	0.137041 (rank : 224)
Query Neighborhood Hits	267	Target Neighborhood Hits	187	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TRI54_HUMAN
θ value	0.47712 (rank : 178)	NC score	0.225718 (rank : 145)
Query Neighborhood Hits	267	Target Neighborhood Hits	209	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	0.47712 (rank : 179)	NC score	0.225243 (rank : 146)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	121
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

UB7I3_MOUSE
θ value	0.47712 (rank : 180)	NC score	0.105933 (rank : 261)
Query Neighborhood Hits	267	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

PCGF4_HUMAN
θ value	0.62314 (rank : 181)	NC score	0.157530 (rank : 192)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	113
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.62314 (rank : 182)	NC score	0.157238 (rank : 193)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RN152_MOUSE
θ value	0.62314 (rank : 183)	NC score	0.131986 (rank : 238)
Query Neighborhood Hits	267	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN165_HUMAN
θ value	0.62314 (rank : 184)	NC score	0.117190 (rank : 247)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

TRAF7_HUMAN
θ value	0.62314 (rank : 185)	NC score	0.107296 (rank : 259)
Query Neighborhood Hits	267	Target Neighborhood Hits	482	Shared Neighborhood Hits	146
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

AMFR2_HUMAN
θ value	0.813845 (rank : 186)	NC score	0.161059 (rank : 186)
Query Neighborhood Hits	267	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	0.813845 (rank : 187)	NC score	0.159312 (rank : 190)
Query Neighborhood Hits	267	Target Neighborhood Hits	208	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

MKRN2_MOUSE
θ value	0.813845 (rank : 188)	NC score	0.082854 (rank : 281)
Query Neighborhood Hits	267	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

ST18_HUMAN
θ value	0.813845 (rank : 189)	NC score	0.023910 (rank : 358)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	9
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

TRAF7_MOUSE
θ value	0.813845 (rank : 190)	NC score	0.107873 (rank : 258)
Query Neighborhood Hits	267	Target Neighborhood Hits	470	Shared Neighborhood Hits	144
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI18_MOUSE
θ value	0.813845 (rank : 191)	NC score	0.194434 (rank : 151)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	151
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI48_HUMAN
θ value	0.813845 (rank : 192)	NC score	0.266166 (rank : 112)
Query Neighborhood Hits	267	Target Neighborhood Hits	192	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI59_MOUSE
θ value	0.813845 (rank : 193)	NC score	0.272423 (rank : 98)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	166
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

UB7I3_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.095482 (rank : 273)
Query Neighborhood Hits	267	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

APC11_MOUSE
θ value	1.06291 (rank : 195)	NC score	0.074202 (rank : 296)
Query Neighborhood Hits	267	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

PZRN4_HUMAN
θ value	1.06291 (rank : 196)	NC score	0.148294 (rank : 208)
Query Neighborhood Hits	267	Target Neighborhood Hits	438	Shared Neighborhood Hits	163
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

RNF32_MOUSE
θ value	1.06291 (rank : 197)	NC score	0.097360 (rank : 271)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_MOUSE
θ value	1.06291 (rank : 198)	NC score	0.105319 (rank : 263)
Query Neighborhood Hits	267	Target Neighborhood Hits	160	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRI65_MOUSE
θ value	1.06291 (rank : 199)	NC score	0.290840 (rank : 75)
Query Neighborhood Hits	267	Target Neighborhood Hits	340	Shared Neighborhood Hits	190
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

UHRF1_HUMAN
θ value	1.06291 (rank : 200)	NC score	0.185110 (rank : 162)
Query Neighborhood Hits	267	Target Neighborhood Hits	272	Shared Neighborhood Hits	136
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

CBLC_MOUSE
θ value	1.38821 (rank : 201)	NC score	0.157763 (rank : 191)
Query Neighborhood Hits	267	Target Neighborhood Hits	186	Shared Neighborhood Hits	129
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

DEK_HUMAN
θ value	1.38821 (rank : 202)	NC score	0.031671 (rank : 354)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

MKRN3_HUMAN
θ value	1.38821 (rank : 203)	NC score	0.072219 (rank : 299)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RBBP6_HUMAN
θ value	1.38821 (rank : 204)	NC score	0.130402 (rank : 240)
Query Neighborhood Hits	267	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	1.38821 (rank : 205)	NC score	0.140783 (rank : 219)
Query Neighborhood Hits	267	Target Neighborhood Hits	1014	Shared Neighborhood Hits	136
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRI49_HUMAN
θ value	1.38821 (rank : 206)	NC score	0.260374 (rank : 125)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	138
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI59_HUMAN
θ value	1.38821 (rank : 207)	NC score	0.269026 (rank : 105)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	165
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

ZN179_HUMAN
θ value	1.38821 (rank : 208)	NC score	0.263253 (rank : 119)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	134
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

LNX1_HUMAN
θ value	1.81305 (rank : 209)	NC score	0.152542 (rank : 200)
Query Neighborhood Hits	267	Target Neighborhood Hits	379	Shared Neighborhood Hits	167
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	1.81305 (rank : 210)	NC score	0.149513 (rank : 206)
Query Neighborhood Hits	267	Target Neighborhood Hits	377	Shared Neighborhood Hits	159
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

MKRN2_HUMAN
θ value	1.81305 (rank : 211)	NC score	0.077276 (rank : 290)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MYT1_HUMAN
θ value	1.81305 (rank : 212)	NC score	0.018998 (rank : 362)
Query Neighborhood Hits	267	Target Neighborhood Hits	475	Shared Neighborhood Hits	9
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

TRI18_HUMAN
θ value	1.81305 (rank : 213)	NC score	0.194367 (rank : 152)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_HUMAN
θ value	1.81305 (rank : 214)	NC score	0.190500 (rank : 156)
Query Neighborhood Hits	267	Target Neighborhood Hits	345	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	1.81305 (rank : 215)	NC score	0.188803 (rank : 158)
Query Neighborhood Hits	267	Target Neighborhood Hits	361	Shared Neighborhood Hits	157
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

BIRC2_HUMAN
θ value	2.36792 (rank : 216)	NC score	0.081655 (rank : 283)
Query Neighborhood Hits	267	Target Neighborhood Hits	142	Shared Neighborhood Hits	87
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	2.36792 (rank : 217)	NC score	0.079346 (rank : 287)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC8_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.082716 (rank : 282)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BRE1B_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.060250 (rank : 331)
Query Neighborhood Hits	267	Target Neighborhood Hits	1040	Shared Neighborhood Hits	131
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	2.36792 (rank : 220)	NC score	0.060750 (rank : 326)
Query Neighborhood Hits	267	Target Neighborhood Hits	970	Shared Neighborhood Hits	129
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

PIN1_MOUSE
θ value	2.36792 (rank : 221)	NC score	0.034409 (rank : 353)
Query Neighborhood Hits	267	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

RNF34_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.099194 (rank : 270)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

TRI65_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.291969 (rank : 70)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	184
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

CTRO_MOUSE
θ value	3.0926 (rank : 224)	NC score	-0.001349 (rank : 372)
Query Neighborhood Hits	267	Target Neighborhood Hits	2344	Shared Neighborhood Hits	54
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DTX3_HUMAN
θ value	3.0926 (rank : 225)	NC score	0.176543 (rank : 168)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	142
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

LY10_HUMAN
θ value	3.0926 (rank : 226)	NC score	0.058564 (rank : 334)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MGRN1_HUMAN
θ value	3.0926 (rank : 227)	NC score	0.109039 (rank : 254)
Query Neighborhood Hits	267	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	3.0926 (rank : 228)	NC score	0.109265 (rank : 253)
Query Neighborhood Hits	267	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RN183_MOUSE
θ value	3.0926 (rank : 229)	NC score	0.159710 (rank : 189)
Query Neighborhood Hits	267	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI15_HUMAN
θ value	3.0926 (rank : 230)	NC score	0.248771 (rank : 132)
Query Neighborhood Hits	267	Target Neighborhood Hits	395	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

CTRO_HUMAN
θ value	4.03905 (rank : 231)	NC score	-0.003991 (rank : 373)
Query Neighborhood Hits	267	Target Neighborhood Hits	2092	Shared Neighborhood Hits	39
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

FXR1_HUMAN
θ value	4.03905 (rank : 232)	NC score	0.007757 (rank : 370)
Query Neighborhood Hits	267	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

MKRN1_HUMAN
θ value	4.03905 (rank : 233)	NC score	0.066005 (rank : 312)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

RN183_HUMAN
θ value	4.03905 (rank : 234)	NC score	0.173092 (rank : 173)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI34_MOUSE
θ value	4.03905 (rank : 235)	NC score	0.247760 (rank : 133)
Query Neighborhood Hits	267	Target Neighborhood Hits	332	Shared Neighborhood Hits	131
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

BARD1_MOUSE
θ value	5.27518 (rank : 236)	NC score	0.055882 (rank : 342)
Query Neighborhood Hits	267	Target Neighborhood Hits	411	Shared Neighborhood Hits	79
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BIRC7_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.156725 (rank : 195)
Query Neighborhood Hits	267	Target Neighborhood Hits	185	Shared Neighborhood Hits	133
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CGRF1_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.046809 (rank : 351)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

DTX2_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.030694 (rank : 355)
Query Neighborhood Hits	267	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

DTX3_MOUSE
θ value	5.27518 (rank : 240)	NC score	0.174982 (rank : 171)
Query Neighborhood Hits	267	Target Neighborhood Hits	202	Shared Neighborhood Hits	144
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

MAGI2_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.013353 (rank : 366)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MKRN4_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.074779 (rank : 291)
Query Neighborhood Hits	267	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MYCB2_MOUSE
θ value	5.27518 (rank : 243)	NC score	0.016143 (rank : 364)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PIN1_HUMAN
θ value	5.27518 (rank : 244)	NC score	0.029040 (rank : 357)
Query Neighborhood Hits	267	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

UB7I1_HUMAN
θ value	5.27518 (rank : 245)	NC score	0.021261 (rank : 360)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
θ value	5.27518 (rank : 246)	NC score	0.020495 (rank : 361)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

ZN364_HUMAN
θ value	5.27518 (rank : 247)	NC score	0.092390 (rank : 276)
Query Neighborhood Hits	267	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	5.27518 (rank : 248)	NC score	0.089195 (rank : 278)
Query Neighborhood Hits	267	Target Neighborhood Hits	140	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

BRE1A_HUMAN
θ value	6.88961 (rank : 249)	NC score	0.052010 (rank : 347)
Query Neighborhood Hits	267	Target Neighborhood Hits	1071	Shared Neighborhood Hits	125
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	6.88961 (rank : 250)	NC score	0.051557 (rank : 349)
Query Neighborhood Hits	267	Target Neighborhood Hits	1025	Shared Neighborhood Hits	122
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DTX1_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.023662 (rank : 359)
Query Neighborhood Hits	267	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

K0776_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.009257 (rank : 369)
Query Neighborhood Hits	267	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

MAGI2_MOUSE
θ value	6.88961 (rank : 253)	NC score	0.012418 (rank : 367)
Query Neighborhood Hits	267	Target Neighborhood Hits	370	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MKRN1_MOUSE
θ value	6.88961 (rank : 254)	NC score	0.063686 (rank : 321)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MYT1_MOUSE
θ value	6.88961 (rank : 255)	NC score	0.016938 (rank : 363)
Query Neighborhood Hits	267	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

RFPL2_HUMAN
θ value	6.88961 (rank : 256)	NC score	0.176068 (rank : 169)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RN133_HUMAN
θ value	6.88961 (rank : 257)	NC score	0.067996 (rank : 306)
Query Neighborhood Hits	267	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

SYCP2_HUMAN
θ value	6.88961 (rank : 258)	NC score	0.035977 (rank : 352)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

ABC8B_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.000009 (rank : 371)
Query Neighborhood Hits	267	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

MYCB2_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.016006 (rank : 365)
Query Neighborhood Hits	267	Target Neighborhood Hits	390	Shared Neighborhood Hits	25
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RFPL3_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.178853 (rank : 167)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	91
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RN167_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.086199 (rank : 280)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.090387 (rank : 277)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	81
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF37_MOUSE
θ value	8.99809 (rank : 264)	NC score	0.067475 (rank : 309)
Query Neighborhood Hits	267	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

SEC62_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.011804 (rank : 368)
Query Neighborhood Hits	267	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

SLIT3_MOUSE
θ value	8.99809 (rank : 266)	NC score	-0.005232 (rank : 374)
Query Neighborhood Hits	267	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TRI36_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.142965 (rank : 214)
Query Neighborhood Hits	267	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

AIRE_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.074504 (rank : 293)
Query Neighborhood Hits	267	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.074440 (rank : 295)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BARD1_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.055169 (rank : 344)
Query Neighborhood Hits	267	Target Neighborhood Hits	427	Shared Neighborhood Hits	83
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.056024 (rank : 341)
Query Neighborhood Hits	267	Target Neighborhood Hits	693	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.054484 (rank : 345)
Query Neighborhood Hits	267	Target Neighborhood Hits	701	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.060016 (rank : 332)
Query Neighborhood Hits	267	Target Neighborhood Hits	394	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BPTF_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.067713 (rank : 307)
Query Neighborhood Hits	267	Target Neighborhood Hits	786	Shared Neighborhood Hits	30
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BSPRY_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.145633 (rank : 210)
Query Neighborhood Hits	267	Target Neighborhood Hits	115	Shared Neighborhood Hits	61
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.149865 (rank : 205)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.134079 (rank : 233)
Query Neighborhood Hits	267	Target Neighborhood Hits	322	Shared Neighborhood Hits	54
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.136977 (rank : 225)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.132460 (rank : 237)
Query Neighborhood Hits	267	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.136602 (rank : 227)
Query Neighborhood Hits	267	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.132976 (rank : 236)
Query Neighborhood Hits	267	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.134974 (rank : 230)
Query Neighborhood Hits	267	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.136033 (rank : 228)
Query Neighborhood Hits	267	Target Neighborhood Hits	233	Shared Neighborhood Hits	55
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.135601 (rank : 229)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.130704 (rank : 239)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.134809 (rank : 231)
Query Neighborhood Hits	267	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CBX5_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.054367 (rank : 346)
Query Neighborhood Hits	267	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CHFR_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.187416 (rank : 159)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	156
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.189194 (rank : 157)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	158
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

ERMAP_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.156987 (rank : 194)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.144469 (rank : 211)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

GOLI_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.065890 (rank : 313)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.066180 (rank : 311)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.050898 (rank : 350)
Query Neighborhood Hits	267	Target Neighborhood Hits	1258	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MEFV_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.185416 (rank : 161)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.174655 (rank : 172)
Query Neighborhood Hits	267	Target Neighborhood Hits	236	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MKRN3_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.051912 (rank : 348)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MNAB_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.056965 (rank : 339)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.057875 (rank : 337)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	94
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PF21A_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.063213 (rank : 323)
Query Neighborhood Hits	267	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.064115 (rank : 318)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.063758 (rank : 320)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.063338 (rank : 322)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.069631 (rank : 303)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.069880 (rank : 301)
Query Neighborhood Hits	267	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PJA1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.065422 (rank : 316)
Query Neighborhood Hits	267	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PJA1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.060626 (rank : 327)
Query Neighborhood Hits	267	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

PKCB1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.063800 (rank : 319)
Query Neighborhood Hits	267	Target Neighborhood Hits	488	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PML_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.111693 (rank : 252)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.100215 (rank : 267)
Query Neighborhood Hits	267	Target Neighborhood Hits	246	Shared Neighborhood Hits	100
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RAD18_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.150420 (rank : 202)
Query Neighborhood Hits	267	Target Neighborhood Hits	284	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.156344 (rank : 196)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RC3H1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.074498 (rank : 294)
Query Neighborhood Hits	267	Target Neighborhood Hits	433	Shared Neighborhood Hits	109
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.078302 (rank : 288)
Query Neighborhood Hits	267	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

RFFL_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.067509 (rank : 308)
Query Neighborhood Hits	267	Target Neighborhood Hits	175	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.070874 (rank : 300)
Query Neighborhood Hits	267	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFPL1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.169012 (rank : 177)
Query Neighborhood Hits	267	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RKHD1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.100128 (rank : 268)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN103_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.065739 (rank : 314)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.069308 (rank : 304)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.060297 (rank : 330)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.060564 (rank : 328)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN123_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.056650 (rank : 340)
Query Neighborhood Hits	267	Target Neighborhood Hits	175	Shared Neighborhood Hits	101
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.061176 (rank : 325)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	101
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN152_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.096499 (rank : 272)
Query Neighborhood Hits	267	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN169_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.161597 (rank : 184)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RNF13_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.072818 (rank : 298)
Query Neighborhood Hits	267	Target Neighborhood Hits	147	Shared Neighborhood Hits	72
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.073147 (rank : 297)
Query Neighborhood Hits	267	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF24_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.065538 (rank : 315)
Query Neighborhood Hits	267	Target Neighborhood Hits	122	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.064509 (rank : 317)
Query Neighborhood Hits	267	Target Neighborhood Hits	124	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RSF1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.061254 (rank : 324)
Query Neighborhood Hits	267	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SP110_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.055219 (rank : 343)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPRY4_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.113627 (rank : 249)
Query Neighborhood Hits	267	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.117584 (rank : 246)
Query Neighborhood Hits	267	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1A_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.106561 (rank : 260)
Query Neighborhood Hits	267	Target Neighborhood Hits	327	Shared Neighborhood Hits	83
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.101696 (rank : 266)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.108223 (rank : 256)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.105839 (rank : 262)
Query Neighborhood Hits	267	Target Neighborhood Hits	276	Shared Neighborhood Hits	90
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.138300 (rank : 221)
Query Neighborhood Hits	267	Target Neighborhood Hits	410	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.141733 (rank : 215)
Query Neighborhood Hits	267	Target Neighborhood Hits	498	Shared Neighborhood Hits	103
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TOPRS_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.153987 (rank : 198)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.150041 (rank : 204)
Query Neighborhood Hits	267	Target Neighborhood Hits	263	Shared Neighborhood Hits	132
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.102105 (rank : 265)
Query Neighborhood Hits	267	Target Neighborhood Hits	402	Shared Neighborhood Hits	108
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.104934 (rank : 264)
Query Neighborhood Hits	267	Target Neighborhood Hits	394	Shared Neighborhood Hits	112
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF4_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.121629 (rank : 242)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.088095 (rank : 279)
Query Neighborhood Hits	267	Target Neighborhood Hits	338	Shared Neighborhood Hits	97
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.119194 (rank : 244)
Query Neighborhood Hits	267	Target Neighborhood Hits	396	Shared Neighborhood Hits	108
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.129878 (rank : 241)
Query Neighborhood Hits	267	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAIP_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.074673 (rank : 292)
Query Neighborhood Hits	267	Target Neighborhood Hits	780	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.068157 (rank : 305)
Query Neighborhood Hits	267	Target Neighborhood Hits	745	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI14_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.163359 (rank : 183)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.161195 (rank : 185)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI16_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.136649 (rank : 226)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI16_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.148676 (rank : 207)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.144200 (rank : 212)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	70
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.140097 (rank : 220)
Query Neighborhood Hits	267	Target Neighborhood Hits	306	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI36_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.137347 (rank : 223)
Query Neighborhood Hits	267	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI37_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.191577 (rank : 155)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	135
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.191593 (rank : 154)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	135
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI42_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.108893 (rank : 255)
Query Neighborhood Hits	267	Target Neighborhood Hits	283	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.108217 (rank : 257)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI44_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.143886 (rank : 213)
Query Neighborhood Hits	267	Target Neighborhood Hits	393	Shared Neighborhood Hits	69
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.147297 (rank : 209)
Query Neighborhood Hits	267	Target Neighborhood Hits	327	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.099980 (rank : 269)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.094777 (rank : 274)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI46_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.150154 (rank : 203)
Query Neighborhood Hits	267	Target Neighborhood Hits	291	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.150632 (rank : 201)
Query Neighborhood Hits	267	Target Neighborhood Hits	287	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI66_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.079347 (rank : 286)
Query Neighborhood Hits	267	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.078228 (rank : 289)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	50
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRIM9_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.141588 (rank : 216)
Query Neighborhood Hits	267	Target Neighborhood Hits	294	Shared Neighborhood Hits	127
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.141315 (rank : 217)
Query Neighborhood Hits	267	Target Neighborhood Hits	274	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

ZMY11_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.060438 (rank : 329)
Query Neighborhood Hits	267	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.059034 (rank : 333)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZSWM2_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.057326 (rank : 338)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

SMRA3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	267
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.991223 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	267	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TTF2_HUMAN
NC score	0.813398 (rank : 3)	θ value	4.84666e-62 (rank : 3)
Query Neighborhood Hits	267	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

SMRCD_MOUSE
NC score	0.768519 (rank : 4)	θ value	3.4976e-36 (rank : 5)
Query Neighborhood Hits	267	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.767395 (rank : 5)	θ value	7.29293e-34 (rank : 6)
Query Neighborhood Hits	267	Target Neighborhood Hits	117	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

TTF2_MOUSE
NC score	0.755883 (rank : 6)	θ value	1.98146e-39 (rank : 4)
Query Neighborhood Hits	267	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

RA54B_HUMAN
NC score	0.739791 (rank : 7)	θ value	2.69047e-20 (rank : 9)
Query Neighborhood Hits	267	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

BTAF1_HUMAN
NC score	0.738742 (rank : 8)	θ value	3.88503e-19 (rank : 18)
Query Neighborhood Hits	267	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

RAD54_HUMAN
NC score	0.737243 (rank : 9)	θ value	2.06002e-20 (rank : 8)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RA54B_MOUSE
NC score	0.735611 (rank : 10)	θ value	4.29542e-18 (rank : 23)
Query Neighborhood Hits	267	Target Neighborhood Hits	59	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_MOUSE
NC score	0.734070 (rank : 11)	θ value	2.97466e-19 (rank : 17)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

ERCC6_HUMAN
NC score	0.727769 (rank : 12)	θ value	9.56915e-18 (rank : 27)
Query Neighborhood Hits	267	Target Neighborhood Hits	247	Shared Neighborhood Hits	42
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA1_HUMAN
NC score	0.723678 (rank : 13)	θ value	1.74391e-19 (rank : 15)
Query Neighborhood Hits	267	Target Neighborhood Hits	105	Shared Neighborhood Hits	39
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.722299 (rank : 14)	θ value	1.74391e-19 (rank : 16)
Query Neighborhood Hits	267	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA5_MOUSE
NC score	0.721470 (rank : 15)	θ value	1.63225e-17 (rank : 29)
Query Neighborhood Hits	267	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.721370 (rank : 16)	θ value	1.63225e-17 (rank : 28)
Query Neighborhood Hits	267	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

INOC1_HUMAN
NC score	0.714698 (rank : 17)	θ value	2.5182e-18 (rank : 21)
Query Neighborhood Hits	267	Target Neighborhood Hits	181	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
NC score	0.714470 (rank : 18)	θ value	1.13037e-18 (rank : 20)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	40
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

CHD2_HUMAN
NC score	0.707206 (rank : 19)	θ value	5.42112e-21 (rank : 7)
Query Neighborhood Hits	267	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD1_MOUSE
NC score	0.704520 (rank : 20)	θ value	4.29542e-18 (rank : 22)
Query Neighborhood Hits	267	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
NC score	0.704202 (rank : 21)	θ value	9.56915e-18 (rank : 26)
Query Neighborhood Hits	267	Target Neighborhood Hits	235	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_HUMAN
NC score	0.700757 (rank : 22)	θ value	7.32683e-18 (rank : 24)
Query Neighborhood Hits	267	Target Neighborhood Hits	337	Shared Neighborhood Hits	40
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD6_HUMAN
NC score	0.698261 (rank : 23)	θ value	7.32683e-18 (rank : 25)
Query Neighborhood Hits	267	Target Neighborhood Hits	342	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_HUMAN
NC score	0.692313 (rank : 24)	θ value	4.74913e-17 (rank : 30)
Query Neighborhood Hits	267	Target Neighborhood Hits	343	Shared Neighborhood Hits	44
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
NC score	0.688529 (rank : 25)	θ value	6.20254e-17 (rank : 31)
Query Neighborhood Hits	267	Target Neighborhood Hits	427	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMCA2_HUMAN
NC score	0.687818 (rank : 26)	θ value	3.88503e-19 (rank : 19)
Query Neighborhood Hits	267	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
NC score	0.678232 (rank : 27)	θ value	7.82807e-20 (rank : 13)
Query Neighborhood Hits	267	Target Neighborhood Hits	597	Shared Neighborhood Hits	44
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMAL1_MOUSE
NC score	0.661131 (rank : 28)	θ value	9.59137e-10 (rank : 34)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

CHD4_HUMAN
NC score	0.656977 (rank : 29)	θ value	7.82807e-20 (rank : 10)
Query Neighborhood Hits	267	Target Neighborhood Hits	365	Shared Neighborhood Hits	50
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.655977 (rank : 30)	θ value	7.82807e-20 (rank : 12)
Query Neighborhood Hits	267	Target Neighborhood Hits	349	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
NC score	0.655876 (rank : 31)	θ value	1.74391e-19 (rank : 14)
Query Neighborhood Hits	267	Target Neighborhood Hits	397	Shared Neighborhood Hits	50
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_MOUSE
NC score	0.654579 (rank : 32)	θ value	7.82807e-20 (rank : 11)
Query Neighborhood Hits	267	Target Neighborhood Hits	408	Shared Neighborhood Hits	51
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMAL1_HUMAN
NC score	0.650843 (rank : 33)	θ value	2.79066e-09 (rank : 35)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

EP400_HUMAN
NC score	0.612167 (rank : 34)	θ value	8.11959e-09 (rank : 36)
Query Neighborhood Hits	267	Target Neighborhood Hits	556	Shared Neighborhood Hits	39
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.605038 (rank : 35)	θ value	6.87365e-08 (rank : 39)
Query Neighborhood Hits	267	Target Neighborhood Hits	592	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ATRX_MOUSE
NC score	0.564771 (rank : 36)	θ value	6.00763e-12 (rank : 33)
Query Neighborhood Hits	267	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.548804 (rank : 37)	θ value	3.52202e-12 (rank : 32)
Query Neighborhood Hits	267	Target Neighborhood Hits	842	Shared Neighborhood Hits	53
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

RN125_MOUSE
NC score	0.373673 (rank : 38)	θ value	1.09739e-05 (rank : 43)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	176
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN185_HUMAN
NC score	0.371011 (rank : 39)	θ value	2.88788e-06 (rank : 40)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	168
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN125_HUMAN
NC score	0.367193 (rank : 40)	θ value	3.19293e-05 (rank : 45)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	175
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN185_MOUSE
NC score	0.364923 (rank : 41)	θ value	8.40245e-06 (rank : 42)
Query Neighborhood Hits	267	Target Neighborhood Hits	211	Shared Neighborhood Hits	168
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRI40_HUMAN
NC score	0.361635 (rank : 42)	θ value	0.000461057 (rank : 62)
Query Neighborhood Hits	267	Target Neighborhood Hits	279	Shared Neighborhood Hits	173
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

BRCA1_HUMAN
NC score	0.356921 (rank : 43)	θ value	4.0297e-08 (rank : 37)
Query Neighborhood Hits	267	Target Neighborhood Hits	381	Shared Neighborhood Hits	175
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
NC score	0.355417 (rank : 44)	θ value	4.0297e-08 (rank : 38)
Query Neighborhood Hits	267	Target Neighborhood Hits	436	Shared Neighborhood Hits	179
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

PEX10_HUMAN
NC score	0.351821 (rank : 45)	θ value	0.00102713 (rank : 64)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	173
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF5_HUMAN
NC score	0.349183 (rank : 46)	θ value	7.1131e-05 (rank : 50)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	159
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.343338 (rank : 47)	θ value	0.00020696 (rank : 54)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	157
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TRI31_HUMAN
NC score	0.342179 (rank : 48)	θ value	4.1701e-05 (rank : 49)
Query Neighborhood Hits	267	Target Neighborhood Hits	299	Shared Neighborhood Hits	180
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI26_MOUSE
NC score	0.326398 (rank : 49)	θ value	7.1131e-05 (rank : 51)
Query Neighborhood Hits	267	Target Neighborhood Hits	339	Shared Neighborhood Hits	186
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
NC score	0.325611 (rank : 50)	θ value	4.1701e-05 (rank : 48)
Query Neighborhood Hits	267	Target Neighborhood Hits	335	Shared Neighborhood Hits	184
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RN168_HUMAN
NC score	0.320508 (rank : 51)	θ value	0.00035302 (rank : 58)
Query Neighborhood Hits	267	Target Neighborhood Hits	370	Shared Neighborhood Hits	172
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI73_HUMAN
NC score	0.316431 (rank : 52)	θ value	0.00509761 (rank : 84)
Query Neighborhood Hits	267	Target Neighborhood Hits	258	Shared Neighborhood Hits	176
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

ZN313_MOUSE
NC score	0.315962 (rank : 53)	θ value	0.0193708 (rank : 98)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	177
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI12_MOUSE
NC score	0.315448 (rank : 54)	θ value	0.00665767 (rank : 88)
Query Neighborhood Hits	267	Target Neighborhood Hits	387	Shared Neighborhood Hits	173
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI74_HUMAN
NC score	0.314327 (rank : 55)	θ value	0.00509761 (rank : 85)
Query Neighborhood Hits	267	Target Neighborhood Hits	249	Shared Neighborhood Hits	171
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

ZN313_HUMAN
NC score	0.311177 (rank : 56)	θ value	0.0252991 (rank : 109)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI52_HUMAN
NC score	0.310116 (rank : 57)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	154
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI43_HUMAN
NC score	0.309984 (rank : 58)	θ value	6.43352e-06 (rank : 41)
Query Neighborhood Hits	267	Target Neighborhood Hits	341	Shared Neighborhood Hits	180
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RN168_MOUSE
NC score	0.303230 (rank : 59)	θ value	0.00175202 (rank : 67)
Query Neighborhood Hits	267	Target Neighborhood Hits	440	Shared Neighborhood Hits	170
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI50_HUMAN
NC score	0.299575 (rank : 60)	θ value	0.000270298 (rank : 57)
Query Neighborhood Hits	267	Target Neighborhood Hits	294	Shared Neighborhood Hits	188
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI30_MOUSE
NC score	0.299533 (rank : 61)	θ value	0.0252991 (rank : 108)
Query Neighborhood Hits	267	Target Neighborhood Hits	434	Shared Neighborhood Hits	176
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

RN146_HUMAN
NC score	0.298208 (rank : 62)	θ value	0.000158464 (rank : 52)
Query Neighborhood Hits	267	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRI50_MOUSE
NC score	0.296896 (rank : 63)	θ value	0.00390308 (rank : 79)
Query Neighborhood Hits	267	Target Neighborhood Hits	326	Shared Neighborhood Hits	188
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI22_HUMAN
NC score	0.296489 (rank : 64)	θ value	0.00228821 (rank : 70)
Query Neighborhood Hits	267	Target Neighborhood Hits	396	Shared Neighborhood Hits	178
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RN146_MOUSE
NC score	0.296341 (rank : 65)	θ value	0.000158464 (rank : 53)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

TRIM5_HUMAN
NC score	0.295811 (rank : 66)	θ value	0.00390308 (rank : 81)
Query Neighborhood Hits	267	Target Neighborhood Hits	424	Shared Neighborhood Hits	182
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI11_MOUSE
NC score	0.292288 (rank : 67)	θ value	3.19293e-05 (rank : 47)
Query Neighborhood Hits	267	Target Neighborhood Hits	329	Shared Neighborhood Hits	184
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.292248 (rank : 68)	θ value	3.19293e-05 (rank : 46)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	183
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI13_HUMAN
NC score	0.292133 (rank : 69)	θ value	0.0736092 (rank : 129)
Query Neighborhood Hits	267	Target Neighborhood Hits	274	Shared Neighborhood Hits	173
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI65_HUMAN
NC score	0.291969 (rank : 70)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	184
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI13_MOUSE
NC score	0.291714 (rank : 71)	θ value	0.125558 (rank : 138)
Query Neighborhood Hits	267	Target Neighborhood Hits	282	Shared Neighborhood Hits	175
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

RO52_MOUSE
NC score	0.291527 (rank : 72)	θ value	2.44474e-05 (rank : 44)
Query Neighborhood Hits	267	Target Neighborhood Hits	360	Shared Neighborhood Hits	178
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

BFAR_MOUSE
NC score	0.291400 (rank : 73)	θ value	0.0252991 (rank : 99)
Query Neighborhood Hits	267	Target Neighborhood Hits	232	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI35_HUMAN
NC score	0.290990 (rank : 74)	θ value	0.21417 (rank : 157)
Query Neighborhood Hits	267	Target Neighborhood Hits	382	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI65_MOUSE
NC score	0.290840 (rank : 75)	θ value	1.06291 (rank : 199)
Query Neighborhood Hits	267	Target Neighborhood Hits	340	Shared Neighborhood Hits	190
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI60_HUMAN
NC score	0.289683 (rank : 76)	θ value	0.00509761 (rank : 83)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	183
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

RO52_HUMAN
NC score	0.288089 (rank : 77)	θ value	0.000461057 (rank : 61)
Query Neighborhood Hits	267	Target Neighborhood Hits	419	Shared Neighborhood Hits	185
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI39_MOUSE
NC score	0.287784 (rank : 78)	θ value	0.00020696 (rank : 56)
Query Neighborhood Hits	267	Target Neighborhood Hits	691	Shared Neighborhood Hits	193
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
NC score	0.287549 (rank : 79)	θ value	0.00020696 (rank : 55)
Query Neighborhood Hits	267	Target Neighborhood Hits	693	Shared Neighborhood Hits	194
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

BFAR_HUMAN
NC score	0.287287 (rank : 80)	θ value	0.0431538 (rank : 117)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	166
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRIM6_MOUSE
NC score	0.287049 (rank : 81)	θ value	0.00134147 (rank : 66)
Query Neighborhood Hits	267	Target Neighborhood Hits	451	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI35_MOUSE
NC score	0.286823 (rank : 82)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	267	Target Neighborhood Hits	465	Shared Neighborhood Hits	182
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM4_HUMAN
NC score	0.286808 (rank : 83)	θ value	0.21417 (rank : 158)
Query Neighborhood Hits	267	Target Neighborhood Hits	321	Shared Neighborhood Hits	171
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI10_HUMAN
NC score	0.286049 (rank : 84)	θ value	0.0252991 (rank : 106)
Query Neighborhood Hits	267	Target Neighborhood Hits	315	Shared Neighborhood Hits	172
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI17_HUMAN
NC score	0.286034 (rank : 85)	θ value	0.00298849 (rank : 72)
Query Neighborhood Hits	267	Target Neighborhood Hits	318	Shared Neighborhood Hits	176
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRIM6_HUMAN
NC score	0.286031 (rank : 86)	θ value	0.00175202 (rank : 69)
Query Neighborhood Hits	267	Target Neighborhood Hits	412	Shared Neighborhood Hits	176
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI25_MOUSE
NC score	0.285518 (rank : 87)	θ value	0.00175202 (rank : 68)
Query Neighborhood Hits	267	Target Neighborhood Hits	446	Shared Neighborhood Hits	176
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

RN166_MOUSE
NC score	0.284513 (rank : 88)	θ value	0.163984 (rank : 147)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	160
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_HUMAN
NC score	0.283587 (rank : 89)	θ value	0.163984 (rank : 146)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	157
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI10_MOUSE
NC score	0.283245 (rank : 90)	θ value	0.0148317 (rank : 93)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	169
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI32_HUMAN
NC score	0.280285 (rank : 91)	θ value	0.00298849 (rank : 73)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	137
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.279348 (rank : 92)	θ value	0.00298849 (rank : 74)
Query Neighborhood Hits	267	Target Neighborhood Hits	271	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI34_HUMAN
NC score	0.278571 (rank : 93)	θ value	0.00298849 (rank : 75)
Query Neighborhood Hits	267	Target Neighborhood Hits	416	Shared Neighborhood Hits	151
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

RNF8_MOUSE
NC score	0.277999 (rank : 94)	θ value	0.0113563 (rank : 91)
Query Neighborhood Hits	267	Target Neighborhood Hits	618	Shared Neighborhood Hits	198
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI38_HUMAN
NC score	0.275470 (rank : 95)	θ value	0.00390308 (rank : 78)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	162
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI68_MOUSE
NC score	0.274687 (rank : 96)	θ value	0.0961366 (rank : 134)
Query Neighborhood Hits	267	Target Neighborhood Hits	356	Shared Neighborhood Hits	183
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RING1_HUMAN
NC score	0.273751 (rank : 97)	θ value	0.0330416 (rank : 113)
Query Neighborhood Hits	267	Target Neighborhood Hits	219	Shared Neighborhood Hits	149
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

TRI59_MOUSE
NC score	0.272423 (rank : 98)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	166
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI68_HUMAN
NC score	0.271329 (rank : 99)	θ value	0.163984 (rank : 150)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	166
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI17_MOUSE
NC score	0.270931 (rank : 100)	θ value	0.00869519 (rank : 90)
Query Neighborhood Hits	267	Target Neighborhood Hits	620	Shared Neighborhood Hits	172
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

RING1_MOUSE
NC score	0.270082 (rank : 101)	θ value	0.0330416 (rank : 114)
Query Neighborhood Hits	267	Target Neighborhood Hits	220	Shared Neighborhood Hits	149
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI62_MOUSE
NC score	0.269968 (rank : 102)	θ value	0.0736092 (rank : 132)
Query Neighborhood Hits	267	Target Neighborhood Hits	478	Shared Neighborhood Hits	164
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM7_MOUSE
NC score	0.269174 (rank : 103)	θ value	0.279714 (rank : 167)
Query Neighborhood Hits	267	Target Neighborhood Hits	358	Shared Neighborhood Hits	162
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI60_MOUSE
NC score	0.269029 (rank : 104)	θ value	0.0736092 (rank : 130)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI59_HUMAN
NC score	0.269026 (rank : 105)	θ value	1.38821 (rank : 207)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	165
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRIM3_HUMAN
NC score	0.268715 (rank : 106)	θ value	0.000786445 (rank : 63)
Query Neighborhood Hits	267	Target Neighborhood Hits	357	Shared Neighborhood Hits	175
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
NC score	0.267818 (rank : 107)	θ value	0.00509761 (rank : 86)
Query Neighborhood Hits	267	Target Neighborhood Hits	330	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.267282 (rank : 108)	θ value	0.00509761 (rank : 87)
Query Neighborhood Hits	267	Target Neighborhood Hits	331	Shared Neighborhood Hits	176
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI25_HUMAN
NC score	0.267003 (rank : 109)	θ value	0.0252991 (rank : 107)
Query Neighborhood Hits	267	Target Neighborhood Hits	472	Shared Neighborhood Hits	176
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIM7_HUMAN
NC score	0.266447 (rank : 110)	θ value	0.365318 (rank : 176)
Query Neighborhood Hits	267	Target Neighborhood Hits	336	Shared Neighborhood Hits	162
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM3_MOUSE
NC score	0.266345 (rank : 111)	θ value	0.00134147 (rank : 65)
Query Neighborhood Hits	267	Target Neighborhood Hits	351	Shared Neighborhood Hits	173
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI48_HUMAN
NC score	0.266166 (rank : 112)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	267	Target Neighborhood Hits	192	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RNF8_HUMAN
NC score	0.265960 (rank : 113)	θ value	0.00390308 (rank : 77)
Query Neighborhood Hits	267	Target Neighborhood Hits	622	Shared Neighborhood Hits	196
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF4_HUMAN
NC score	0.265845 (rank : 114)	θ value	0.365318 (rank : 173)
Query Neighborhood Hits	267	Target Neighborhood Hits	212	Shared Neighborhood Hits	154
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

TRI62_HUMAN
NC score	0.264406 (rank : 115)	θ value	0.0736092 (rank : 131)
Query Neighborhood Hits	267	Target Neighborhood Hits	584	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RING2_HUMAN
NC score	0.263779 (rank : 116)	θ value	0.0193708 (rank : 95)
Query Neighborhood Hits	267	Target Neighborhood Hits	201	Shared Neighborhood Hits	147
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

TRI41_HUMAN
NC score	0.263742 (rank : 117)	θ value	0.00298849 (rank : 76)
Query Neighborhood Hits	267	Target Neighborhood Hits	349	Shared Neighborhood Hits	145
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

RING2_MOUSE
NC score	0.263719 (rank : 118)	θ value	0.0193708 (rank : 96)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	147
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

ZN179_HUMAN
NC score	0.263253 (rank : 119)	θ value	1.38821 (rank : 208)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	134
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

RNF4_MOUSE
NC score	0.263007 (rank : 120)	θ value	0.365318 (rank : 174)
Query Neighborhood Hits	267	Target Neighborhood Hits	212	Shared Neighborhood Hits	152
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRIM8_HUMAN
NC score	0.261355 (rank : 121)	θ value	0.163984 (rank : 151)
Query Neighborhood Hits	267	Target Neighborhood Hits	650	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RN141_HUMAN
NC score	0.260896 (rank : 122)	θ value	0.000461057 (rank : 59)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	142
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRIM8_MOUSE
NC score	0.260515 (rank : 123)	θ value	0.163984 (rank : 152)
Query Neighborhood Hits	267	Target Neighborhood Hits	674	Shared Neighborhood Hits	156
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI27_HUMAN
NC score	0.260495 (rank : 124)	θ value	0.125558 (rank : 139)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	163
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI49_HUMAN
NC score	0.260374 (rank : 125)	θ value	1.38821 (rank : 206)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	138
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

RN141_MOUSE
NC score	0.260069 (rank : 126)	θ value	0.000461057 (rank : 60)
Query Neighborhood Hits	267	Target Neighborhood Hits	200	Shared Neighborhood Hits	142
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRI27_MOUSE
NC score	0.257997 (rank : 127)	θ value	0.125558 (rank : 140)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	158
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI56_HUMAN
NC score	0.253313 (rank : 128)	θ value	0.00390308 (rank : 80)
Query Neighborhood Hits	267	Target Neighborhood Hits	339	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI47_MOUSE
NC score	0.252510 (rank : 129)	θ value	0.279714 (rank : 166)
Query Neighborhood Hits	267	Target Neighborhood Hits	295	Shared Neighborhood Hits	155
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI47_HUMAN
NC score	0.252268 (rank : 130)	θ value	0.279714 (rank : 165)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	156
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

RAG1_HUMAN
NC score	0.249756 (rank : 131)	θ value	0.0193708 (rank : 94)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	141
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

TRI15_HUMAN
NC score	0.248771 (rank : 132)	θ value	3.0926 (rank : 230)
Query Neighborhood Hits	267	Target Neighborhood Hits	395	Shared Neighborhood Hits	155
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI34_MOUSE
NC score	0.247760 (rank : 133)	θ value	4.03905 (rank : 235)
Query Neighborhood Hits	267	Target Neighborhood Hits	332	Shared Neighborhood Hits	131
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

RNF41_MOUSE
NC score	0.241798 (rank : 134)	θ value	0.21417 (rank : 156)
Query Neighborhood Hits	267	Target Neighborhood Hits	224	Shared Neighborhood Hits	152
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.241660 (rank : 135)	θ value	0.21417 (rank : 155)
Query Neighborhood Hits	267	Target Neighborhood Hits	226	Shared Neighborhood Hits	152
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RAG1_MOUSE
NC score	0.239893 (rank : 136)	θ value	0.0961366 (rank : 133)
Query Neighborhood Hits	267	Target Neighborhood Hits	189	Shared Neighborhood Hits	143
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRAF6_MOUSE
NC score	0.237411 (rank : 137)	θ value	0.00509761 (rank : 82)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	155
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI56_MOUSE
NC score	0.235327 (rank : 138)	θ value	0.0330416 (rank : 116)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	151
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

R113A_HUMAN
NC score	0.233316 (rank : 139)	θ value	0.00869519 (rank : 89)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	129
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

TRI55_HUMAN
NC score	0.232654 (rank : 140)	θ value	0.0563607 (rank : 123)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRAF6_HUMAN
NC score	0.232548 (rank : 141)	θ value	0.00298849 (rank : 71)
Query Neighborhood Hits	267	Target Neighborhood Hits	267	Shared Neighborhood Hits	153
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI63_MOUSE
NC score	0.231745 (rank : 142)	θ value	0.163984 (rank : 149)
Query Neighborhood Hits	267	Target Neighborhood Hits	240	Shared Neighborhood Hits	119
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI63_HUMAN
NC score	0.227358 (rank : 143)	θ value	0.125558 (rank : 141)
Query Neighborhood Hits	267	Target Neighborhood Hits	298	Shared Neighborhood Hits	118
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

RNF39_HUMAN
NC score	0.226538 (rank : 144)	θ value	0.365318 (rank : 172)
Query Neighborhood Hits	267	Target Neighborhood Hits	200	Shared Neighborhood Hits	137
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI54_HUMAN
NC score	0.225718 (rank : 145)	θ value	0.47712 (rank : 178)
Query Neighborhood Hits	267	Target Neighborhood Hits	209	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
NC score	0.225243 (rank : 146)	θ value	0.47712 (rank : 179)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	121
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

UHRF2_HUMAN
NC score	0.224778 (rank : 147)	θ value	0.0193708 (rank : 97)
Query Neighborhood Hits	267	Target Neighborhood Hits	269	Shared Neighborhood Hits	149
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.216691 (rank : 148)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	267	Target Neighborhood Hits	275	Shared Neighborhood Hits	149
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

R113B_HUMAN
NC score	0.216193 (rank : 149)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	127
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

PCGF6_MOUSE
NC score	0.194708 (rank : 150)	θ value	0.0252991 (rank : 103)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	120
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI18_MOUSE
NC score	0.194434 (rank : 151)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	267	Target Neighborhood Hits	292	Shared Neighborhood Hits	151
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.194367 (rank : 152)	θ value	1.81305 (rank : 213)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	153
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

CM007_MOUSE
NC score	0.193389 (rank : 153)	θ value	0.21417 (rank : 154)
Query Neighborhood Hits	267	Target Neighborhood Hits	416	Shared Neighborhood Hits	126
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TRI37_MOUSE
NC score	0.191593 (rank : 154)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	135
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.191577 (rank : 155)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	135
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRIM1_HUMAN
NC score	0.190500 (rank : 156)	θ value	1.81305 (rank : 214)
Query Neighborhood Hits	267	Target Neighborhood Hits	345	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

CHFR_MOUSE
NC score	0.189194 (rank : 157)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	267	Target Neighborhood Hits	264	Shared Neighborhood Hits	158
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRIM1_MOUSE
NC score	0.188803 (rank : 158)	θ value	1.81305 (rank : 215)
Query Neighborhood Hits	267	Target Neighborhood Hits	361	Shared Neighborhood Hits	157
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

CHFR_HUMAN
NC score	0.187416 (rank : 159)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	267	Target Neighborhood Hits	255	Shared Neighborhood Hits	156
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PCGF6_HUMAN
NC score	0.186324 (rank : 160)	θ value	0.279714 (rank : 164)
Query Neighborhood Hits	267	Target Neighborhood Hits	178	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

MEFV_HUMAN
NC score	0.185416 (rank : 161)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	267	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

UHRF1_HUMAN
NC score	0.185110 (rank : 162)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	267	Target Neighborhood Hits	272	Shared Neighborhood Hits	136
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RFWD2_MOUSE
NC score	0.183858 (rank : 163)	θ value	0.0252991 (rank : 104)
Query Neighborhood Hits	267	Target Neighborhood Hits	535	Shared Neighborhood Hits	180
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

UHRF1_MOUSE
NC score	0.183080 (rank : 164)	θ value	0.279714 (rank : 168)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	138
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RFWD2_HUMAN
NC score	0.181907 (rank : 165)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	267	Target Neighborhood Hits	518	Shared Neighborhood Hits	179
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

CM007_HUMAN
NC score	0.180224 (rank : 166)	θ value	0.21417 (rank : 153)
Query Neighborhood Hits	267	Target Neighborhood Hits	422	Shared Neighborhood Hits	122
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

RFPL3_HUMAN
NC score	0.178853 (rank : 167)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	91
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

DTX3_HUMAN
NC score	0.176543 (rank : 168)	θ value	3.0926 (rank : 225)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	142
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RFPL2_HUMAN
NC score	0.176068 (rank : 169)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	83
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

CBLC_HUMAN
NC score	0.175433 (rank : 170)	θ value	0.0330416 (rank : 110)
Query Neighborhood Hits	267	Target Neighborhood Hits	173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

DTX3_MOUSE
NC score	0.174982 (rank : 171)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	267	Target Neighborhood Hits	202	Shared Neighborhood Hits	144
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

MEFV_MOUSE
NC score	0.174655 (rank : 172)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	267	Target Neighborhood Hits	236	Shared Neighborhood Hits	76
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RN183_HUMAN
NC score	0.173092 (rank : 173)	θ value	4.03905 (rank : 234)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	94
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

NHLC1_MOUSE
NC score	0.171278 (rank : 174)	θ value	0.125558 (rank : 136)
Query Neighborhood Hits	267	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

CBL_MOUSE
NC score	0.169591 (rank : 175)	θ value	0.0252991 (rank : 101)
Query Neighborhood Hits	267	Target Neighborhood Hits	426	Shared Neighborhood Hits	150
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

NHLC1_HUMAN
NC score	0.169227 (rank : 176)	θ value	0.0148317 (rank : 92)
Query Neighborhood Hits	267	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RFPL1_HUMAN
NC score	0.169012 (rank : 177)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	267	Target Neighborhood Hits	119	Shared Neighborhood Hits	80
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

CBL_HUMAN
NC score	0.167263 (rank : 178)	θ value	0.0252991 (rank : 100)
Query Neighborhood Hits	267	Target Neighborhood Hits	353	Shared Neighborhood Hits	144
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

LNX2_HUMAN
NC score	0.164970 (rank : 179)	θ value	0.0330416 (rank : 111)
Query Neighborhood Hits	267	Target Neighborhood Hits	389	Shared Neighborhood Hits	164
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
NC score	0.164765 (rank : 180)	θ value	0.0252991 (rank : 102)
Query Neighborhood Hits	267	Target Neighborhood Hits	407	Shared Neighborhood Hits	163
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

PCGF2_MOUSE
NC score	0.164351 (rank : 181)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	267	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.164292 (rank : 182)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	267	Target Neighborhood Hits	222	Shared Neighborhood Hits	111
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

TRI14_HUMAN
NC score	0.163359 (rank : 183)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	73
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

RN169_HUMAN
NC score	0.161597 (rank : 184)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	267	Target Neighborhood Hits	203	Shared Neighborhood Hits	111
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI14_MOUSE
NC score	0.161195 (rank : 185)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

AMFR2_HUMAN
NC score	0.161059 (rank : 186)	θ value	0.813845 (rank : 186)
Query Neighborhood Hits	267	Target Neighborhood Hits	219	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

CBLB_HUMAN
NC score	0.160698 (rank : 187)	θ value	0.0736092 (rank : 124)
Query Neighborhood Hits	267	Target Neighborhood Hits	261	Shared Neighborhood Hits	140
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
NC score	0.159847 (rank : 188)	θ value	0.0736092 (rank : 125)
Query Neighborhood Hits	267	Target Neighborhood Hits	277	Shared Neighborhood Hits	139
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

RN183_MOUSE
NC score	0.159710 (rank : 189)	θ value	3.0926 (rank : 229)
Query Neighborhood Hits	267	Target Neighborhood Hits	119	Shared Neighborhood Hits	88
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

AMFR_MOUSE
NC score	0.159312 (rank : 190)	θ value	0.813845 (rank : 187)
Query Neighborhood Hits	267	Target Neighborhood Hits	208	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CBLC_MOUSE
NC score	0.157763 (rank : 191)	θ value	1.38821 (rank : 201)
Query Neighborhood Hits	267	Target Neighborhood Hits	186	Shared Neighborhood Hits	129
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

PCGF4_HUMAN
NC score	0.157530 (rank : 192)	θ value	0.62314 (rank : 181)
Query Neighborhood Hits	267	Target Neighborhood Hits	161	Shared Neighborhood Hits	113
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.157238 (rank : 193)	θ value	0.62314 (rank : 182)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	112
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

ERMAP_HUMAN
NC score	0.156987 (rank : 194)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	53
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

BIRC7_HUMAN
NC score	0.156725 (rank : 195)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	267	Target Neighborhood Hits	185	Shared Neighborhood Hits	133
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

RAD18_MOUSE
NC score	0.156344 (rank : 196)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	125
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

PZRN3_MOUSE
NC score	0.155352 (rank : 197)	θ value	0.0563607 (rank : 121)
Query Neighborhood Hits	267	Target Neighborhood Hits	447	Shared Neighborhood Hits	161
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TOPRS_HUMAN
NC score	0.153987 (rank : 198)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	267	Target Neighborhood Hits	286	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PZRN3_HUMAN
NC score	0.153613 (rank : 199)	θ value	0.0563607 (rank : 120)
Query Neighborhood Hits	267	Target Neighborhood Hits	461	Shared Neighborhood Hits	161
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LNX1_HUMAN
NC score	0.152542 (rank : 200)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	267	Target Neighborhood Hits	379	Shared Neighborhood Hits	167
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI46_MOUSE
NC score	0.150632 (rank : 201)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	267	Target Neighborhood Hits	287	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

RAD18_HUMAN
NC score	0.150420 (rank : 202)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	267	Target Neighborhood Hits	284	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

TRI46_HUMAN
NC score	0.150154 (rank : 203)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	267	Target Neighborhood Hits	291	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TOPRS_MOUSE
NC score	0.150041 (rank : 204)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	267	Target Neighborhood Hits	263	Shared Neighborhood Hits	132
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

BSPRY_MOUSE
NC score	0.149865 (rank : 205)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

LNX1_MOUSE
NC score	0.149513 (rank : 206)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	267	Target Neighborhood Hits	377	Shared Neighborhood Hits	159
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

TRI16_MOUSE
NC score	0.148676 (rank : 207)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

PZRN4_HUMAN
NC score	0.148294 (rank : 208)	θ value	1.06291 (rank : 196)
Query Neighborhood Hits	267	Target Neighborhood Hits	438	Shared Neighborhood Hits	163
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRI44_MOUSE
NC score	0.147297 (rank : 209)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	267	Target Neighborhood Hits	327	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

BSPRY_HUMAN
NC score	0.145633 (rank : 210)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	267	Target Neighborhood Hits	115	Shared Neighborhood Hits	61
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

ERMAP_MOUSE
NC score	0.144469 (rank : 211)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI29_HUMAN
NC score	0.144200 (rank : 212)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	267	Target Neighborhood Hits	273	Shared Neighborhood Hits	70
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI44_HUMAN
NC score	0.143886 (rank : 213)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	267	Target Neighborhood Hits	393	Shared Neighborhood Hits	69
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI36_HUMAN
NC score	0.142965 (rank : 214)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	267	Target Neighborhood Hits	282	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TIF1G_MOUSE
NC score	0.141733 (rank : 215)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	267	Target Neighborhood Hits	498	Shared Neighborhood Hits	103
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRIM9_HUMAN
NC score	0.141588 (rank : 216)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	267	Target Neighborhood Hits	294	Shared Neighborhood Hits	127
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
NC score	0.141315 (rank : 217)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	267	Target Neighborhood Hits	274	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RNF26_HUMAN
NC score	0.140887 (rank : 218)	θ value	0.365318 (rank : 171)
Query Neighborhood Hits	267	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RBBP6_MOUSE
NC score	0.140783 (rank : 219)	θ value	1.38821 (rank : 205)
Query Neighborhood Hits	267	Target Neighborhood Hits	1014	Shared Neighborhood Hits	136
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRI29_MOUSE
NC score	0.140097 (rank : 220)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	267	Target Neighborhood Hits	306	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TIF1G_HUMAN
NC score	0.138300 (rank : 221)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	267	Target Neighborhood Hits	410	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRAF3_MOUSE
NC score	0.138188 (rank : 222)	θ value	0.0252991 (rank : 105)
Query Neighborhood Hits	267	Target Neighborhood Hits	476	Shared Neighborhood Hits	122
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI36_MOUSE
NC score	0.137347 (rank : 223)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	267	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

DTX3L_HUMAN
NC score	0.137041 (rank : 224)	θ value	0.47712 (rank : 177)
Query Neighborhood Hits	267	Target Neighborhood Hits	187	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

BT1A1_MOUSE
NC score	0.136977 (rank : 225)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRI16_HUMAN
NC score	0.136649 (rank : 226)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	66
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BT2A2_HUMAN
NC score	0.136602 (rank : 227)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	267	Target Neighborhood Hits	191	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT3A3_HUMAN
NC score	0.136033 (rank : 228)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	267	Target Neighborhood Hits	233	Shared Neighborhood Hits	55
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
NC score	0.135601 (rank : 229)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT3A1_HUMAN
NC score	0.134974 (rank : 230)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	267	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BTNL9_HUMAN
NC score	0.134809 (rank : 231)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	267	Target Neighborhood Hits	125	Shared Neighborhood Hits	53
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

TRAF3_HUMAN
NC score	0.134122 (rank : 232)	θ value	0.0330416 (rank : 115)
Query Neighborhood Hits	267	Target Neighborhood Hits	463	Shared Neighborhood Hits	116
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

BT1A1_HUMAN
NC score	0.134079 (rank : 233)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	267	Target Neighborhood Hits	322	Shared Neighborhood Hits	54
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

PEX2_MOUSE
NC score	0.133892 (rank : 234)	θ value	0.0431538 (rank : 119)
Query Neighborhood Hits	267	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RNF32_HUMAN
NC score	0.133217 (rank : 235)	θ value	0.163984 (rank : 148)
Query Neighborhood Hits	267	Target Neighborhood Hits	133	Shared Neighborhood Hits	72
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

BT2A3_HUMAN
NC score	0.132976 (rank : 236)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	267	Target Neighborhood Hits	195	Shared Neighborhood Hits	53
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT2A1_HUMAN
NC score	0.132460 (rank : 237)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	267	Target Neighborhood Hits	185	Shared Neighborhood Hits	54
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

RN152_MOUSE
NC score	0.131986 (rank : 238)	θ value	0.62314 (rank : 183)
Query Neighborhood Hits	267	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

BTNL8_HUMAN
NC score	0.130704 (rank : 239)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

RBBP6_HUMAN
NC score	0.130402 (rank : 240)	θ value	1.38821 (rank : 204)
Query Neighborhood Hits	267	Target Neighborhood Hits	1135	Shared Neighborhood Hits	138
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TRAF5_MOUSE
NC score	0.129878 (rank : 241)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	267	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF4_HUMAN
NC score	0.121629 (rank : 242)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

NEUL1_HUMAN
NC score	0.120942 (rank : 243)	θ value	0.279714 (rank : 163)
Query Neighborhood Hits	267	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

TRAF5_HUMAN
NC score	0.119194 (rank : 244)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	267	Target Neighborhood Hits	396	Shared Neighborhood Hits	108
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

NEURL_MOUSE
NC score	0.118153 (rank : 245)	θ value	0.365318 (rank : 170)
Query Neighborhood Hits	267	Target Neighborhood Hits	106	Shared Neighborhood Hits	61
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

SPRY4_MOUSE
NC score	0.117584 (rank : 246)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	267	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

RN165_HUMAN
NC score	0.117190 (rank : 247)	θ value	0.62314 (rank : 184)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN126_MOUSE
NC score	0.115373 (rank : 248)	θ value	0.125558 (rank : 137)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

SPRY4_HUMAN
NC score	0.113627 (rank : 249)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	267	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

RN126_HUMAN
NC score	0.113581 (rank : 250)	θ value	0.0736092 (rank : 128)
Query Neighborhood Hits	267	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

PEX2_HUMAN
NC score	0.112121 (rank : 251)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

PML_HUMAN
NC score	0.111693 (rank : 252)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	267	Target Neighborhood Hits	248	Shared Neighborhood Hits	96
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

MGRN1_MOUSE
NC score	0.109265 (rank : 253)	θ value	3.0926 (rank : 228)
Query Neighborhood Hits	267	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MGRN1_HUMAN
NC score	0.109039 (rank : 254)	θ value	3.0926 (rank : 227)
Query Neighborhood Hits	267	Target Neighborhood Hits	192	Shared Neighborhood Hits	95
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

TRI42_HUMAN
NC score	0.108893 (rank : 255)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	267	Target Neighborhood Hits	283	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TIF1B_HUMAN
NC score	0.108223 (rank : 256)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	267	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI42_MOUSE
NC score	0.108217 (rank : 257)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	267	Target Neighborhood Hits	316	Shared Neighborhood Hits	107
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRAF7_MOUSE
NC score	0.107873 (rank : 258)	θ value	0.813845 (rank : 190)
Query Neighborhood Hits	267	Target Neighborhood Hits	470	Shared Neighborhood Hits	144
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF7_HUMAN
NC score	0.107296 (rank : 259)	θ value	0.62314 (rank : 185)
Query Neighborhood Hits	267	Target Neighborhood Hits	482	Shared Neighborhood Hits	146
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TIF1A_HUMAN
NC score	0.106561 (rank : 260)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	267	Target Neighborhood Hits	327	Shared Neighborhood Hits	83
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

UB7I3_MOUSE
NC score	0.105933 (rank : 261)	θ value	0.47712 (rank : 180)
Query Neighborhood Hits	267	Target Neighborhood Hits	131	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

TIF1B_MOUSE
NC score	0.105839 (rank : 262)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	267	Target Neighborhood Hits	276	Shared Neighborhood Hits	90
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RNF34_MOUSE
NC score	0.105319 (rank : 263)	θ value	1.06291 (rank : 198)
Query Neighborhood Hits	267	Target Neighborhood Hits	160	Shared Neighborhood Hits	81
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

TRAF2_MOUSE
NC score	0.104934 (rank : 264)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	267	Target Neighborhood Hits	394	Shared Neighborhood Hits	112
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF2_HUMAN
NC score	0.102105 (rank : 265)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	267	Target Neighborhood Hits	402	Shared Neighborhood Hits	108
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TIF1A_MOUSE
NC score	0.101696 (rank : 266)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PML_MOUSE
NC score	0.100215 (rank : 267)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	267	Target Neighborhood Hits	246	Shared Neighborhood Hits	100
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RKHD1_HUMAN
NC score	0.100128 (rank : 268)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	267	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TRI45_HUMAN
NC score	0.099980 (rank : 269)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

RNF34_HUMAN
NC score	0.099194 (rank : 270)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF32_MOUSE
NC score	0.097360 (rank : 271)	θ value	1.06291 (rank : 197)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RN152_HUMAN
NC score	0.096499 (rank : 272)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	267	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

UB7I3_HUMAN
NC score	0.095482 (rank : 273)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	267	Target Neighborhood Hits	136	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

TRI45_MOUSE
NC score	0.094777 (rank : 274)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	267	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

BIRC3_HUMAN
NC score	0.093190 (rank : 275)	θ value	0.365318 (rank : 169)
Query Neighborhood Hits	267	Target Neighborhood Hits	133	Shared Neighborhood Hits	84
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

ZN364_HUMAN
NC score	0.092390 (rank : 276)	θ value	5.27518 (rank : 247)
Query Neighborhood Hits	267	Target Neighborhood Hits	140	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RN167_MOUSE
NC score	0.090387 (rank : 277)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	81
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

ZN364_MOUSE
NC score	0.089195 (rank : 278)	θ value	5.27518 (rank : 248)
Query Neighborhood Hits	267	Target Neighborhood Hits	140	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

TRAF4_MOUSE
NC score	0.088095 (rank : 279)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	267	Target Neighborhood Hits	338	Shared Neighborhood Hits	97
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

RN167_HUMAN
NC score	0.086199 (rank : 280)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	267	Target Neighborhood Hits	157	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

MKRN2_MOUSE
NC score	0.082854 (rank : 281)	θ value	0.813845 (rank : 188)
Query Neighborhood Hits	267	Target Neighborhood Hits	130	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

BIRC8_HUMAN
NC score	0.082716 (rank : 282)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC2_HUMAN
NC score	0.081655 (rank : 283)	θ value	2.36792 (rank : 216)
Query Neighborhood Hits	267	Target Neighborhood Hits	142	Shared Neighborhood Hits	87
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC3_MOUSE
NC score	0.081610 (rank : 284)	θ value	0.125558 (rank : 135)
Query Neighborhood Hits	267	Target Neighborhood Hits	113	Shared Neighborhood Hits	68
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

APC11_HUMAN
NC score	0.080574 (rank : 285)	θ value	0.163984 (rank : 142)
Query Neighborhood Hits	267	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYG5, Q502X9, Q9BW64, Q9P0R2	Gene names	ANAPC11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11) (Hepatocellular carcinoma-associated RING finger protein).

TRI66_HUMAN
NC score	0.079347 (rank : 286)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	267	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BIRC2_MOUSE
NC score	0.079346 (rank : 287)	θ value	2.36792 (rank : 217)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

RC3H1_MOUSE
NC score	0.078302 (rank : 288)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	267	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRI66_MOUSE
NC score	0.078228 (rank : 289)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	267	Target Neighborhood Hits	491	Shared Neighborhood Hits	50
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

MKRN2_HUMAN
NC score	0.077276 (rank : 290)	θ value	1.81305 (rank : 211)
Query Neighborhood Hits	267	Target Neighborhood Hits	129	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN4_HUMAN
NC score	0.074779 (rank : 291)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	267	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

TRAIP_HUMAN
NC score	0.074673 (rank : 292)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	267	Target Neighborhood Hits	780	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

AIRE_HUMAN
NC score	0.074504 (rank : 293)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	267	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

RC3H1_HUMAN
NC score	0.074498 (rank : 294)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	267	Target Neighborhood Hits	433	Shared Neighborhood Hits	109
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

AIRE_MOUSE
NC score	0.074440 (rank : 295)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

APC11_MOUSE
NC score	0.074202 (rank : 296)	θ value	1.06291 (rank : 195)
Query Neighborhood Hits	267	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q9CPX9, Q3UWH1, Q9CTG0	Gene names	Anapc11
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 11 (APC11) (Cyclosome subunit 11).

RNF13_MOUSE
NC score	0.073147 (rank : 297)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	267	Target Neighborhood Hits	164	Shared Neighborhood Hits	80
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF13_HUMAN
NC score	0.072818 (rank : 298)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	267	Target Neighborhood Hits	147	Shared Neighborhood Hits	72
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

MKRN3_HUMAN
NC score	0.072219 (rank : 299)	θ value	1.38821 (rank : 203)
Query Neighborhood Hits	267	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RFFL_MOUSE
NC score	0.070874 (rank : 300)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	267	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

PHF12_MOUSE
NC score	0.069880 (rank : 301)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	267	Target Neighborhood Hits	172	Shared Neighborhood Hits	11
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

LRSM1_MOUSE
NC score	0.069812 (rank : 302)	θ value	0.0330416 (rank : 112)
Query Neighborhood Hits	267	Target Neighborhood Hits	874	Shared Neighborhood Hits	83
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

PHF12_HUMAN
NC score	0.069631 (rank : 303)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

RN103_MOUSE
NC score	0.069308 (rank : 304)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	267	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

TRAIP_MOUSE
NC score	0.068157 (rank : 305)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	267	Target Neighborhood Hits	745	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RN133_HUMAN
NC score	0.067996 (rank : 306)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	267	Target Neighborhood Hits	108	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

BPTF_HUMAN
NC score	0.067713 (rank : 307)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	267	Target Neighborhood Hits	786	Shared Neighborhood Hits	30
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

RFFL_HUMAN
NC score	0.067509 (rank : 308)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	267	Target Neighborhood Hits	175	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF37_MOUSE
NC score	0.067475 (rank : 309)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	267	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

LRSM1_HUMAN
NC score	0.067261 (rank : 310)	θ value	0.0431538 (rank : 118)
Query Neighborhood Hits	267	Target Neighborhood Hits	1078	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

GOLI_MOUSE
NC score	0.066180 (rank : 311)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	267	Target Neighborhood Hits	134	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

MKRN1_HUMAN
NC score	0.066005 (rank : 312)	θ value	4.03905 (rank : 233)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

GOLI_HUMAN
NC score	0.065890 (rank : 313)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

RN103_HUMAN
NC score	0.065739 (rank : 314)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	267	Target Neighborhood Hits	153	Shared Neighborhood Hits	76
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RNF24_HUMAN
NC score	0.065538 (rank : 315)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	267	Target Neighborhood Hits	122	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

PJA1_HUMAN
NC score	0.065422 (rank : 316)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	267	Target Neighborhood Hits	159	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RNF24_MOUSE
NC score	0.064509 (rank : 317)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	267	Target Neighborhood Hits	124	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

PF21A_MOUSE
NC score	0.064115 (rank : 318)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	267	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PKCB1_HUMAN
NC score	0.063800 (rank : 319)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	267	Target Neighborhood Hits	488	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_HUMAN
NC score	0.063758 (rank : 320)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	267	Target Neighborhood Hits	197	Shared Neighborhood Hits	13
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MKRN1_MOUSE
NC score	0.063686 (rank : 321)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

PF21B_MOUSE
NC score	0.063338 (rank : 322)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	267	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21A_HUMAN
NC score	0.063213 (rank : 323)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	267	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RSF1_HUMAN
NC score	0.061254 (rank : 324)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	267	Target Neighborhood Hits	539	Shared Neighborhood Hits	25
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RN123_MOUSE
NC score	0.061176 (rank : 325)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	267	Target Neighborhood Hits	174	Shared Neighborhood Hits	101
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BRE1B_MOUSE
NC score	0.060750 (rank : 326)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	267	Target Neighborhood Hits	970	Shared Neighborhood Hits	129
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

PJA1_MOUSE
NC score	0.060626 (rank : 327)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	267	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN122_MOUSE
NC score	0.060564 (rank : 328)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

ZMY11_HUMAN
NC score	0.060438 (rank : 329)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	267	Target Neighborhood Hits	201	Shared Neighborhood Hits	17
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

RN122_HUMAN
NC score	0.060297 (rank : 330)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	267	Target Neighborhood Hits	121	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BRE1B_HUMAN
NC score	0.060250 (rank : 331)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	267	Target Neighborhood Hits	1040	Shared Neighborhood Hits	131
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BAZ1B_MOUSE
NC score	0.060016 (rank : 332)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	267	Target Neighborhood Hits	394	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

ZMY11_MOUSE
NC score	0.059034 (rank : 333)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	267	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

LY10_HUMAN
NC score	0.058564 (rank : 334)	θ value	3.0926 (rank : 226)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

XPO4_MOUSE
NC score	0.058259 (rank : 335)	θ value	0.21417 (rank : 161)
Query Neighborhood Hits	267	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESJ0, Q6ZPJ4	Gene names	Xpo4, Kiaa1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

XPO4_HUMAN
NC score	0.058185 (rank : 336)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	267	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0E2, Q5VUZ5, Q9H934	Gene names	XPO4, KIAA1721
Domain Architecture	No domain graphic available
Description	Exportin-4 (Exp4).

MNAB_MOUSE
NC score	0.057875 (rank : 337)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	267	Target Neighborhood Hits	231	Shared Neighborhood Hits	94
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

ZSWM2_HUMAN
NC score	0.057326 (rank : 338)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	267	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MNAB_HUMAN
NC score	0.056965 (rank : 339)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	267	Target Neighborhood Hits	196	Shared Neighborhood Hits	93
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

RN123_HUMAN
NC score	0.056650 (rank : 340)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	267	Target Neighborhood Hits	175	Shared Neighborhood Hits	101
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

BAZ1A_HUMAN
NC score	0.056024 (rank : 341)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	267	Target Neighborhood Hits	693	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BARD1_MOUSE
NC score	0.055882 (rank : 342)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	267	Target Neighborhood Hits	411	Shared Neighborhood Hits	79
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

SP110_HUMAN
NC score	0.055219 (rank : 343)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	267	Target Neighborhood Hits	141	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

BARD1_HUMAN
NC score	0.055169 (rank : 344)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	267	Target Neighborhood Hits	427	Shared Neighborhood Hits	83
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BAZ1B_HUMAN
NC score	0.054484 (rank : 345)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	267	Target Neighborhood Hits	701	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CBX5_HUMAN
NC score	0.054367 (rank : 346)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	267	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

BRE1A_HUMAN
NC score	0.052010 (rank : 347)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	267	Target Neighborhood Hits	1071	Shared Neighborhood Hits	125
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

MKRN3_MOUSE
NC score	0.051912 (rank : 348)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	267	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

BRE1A_MOUSE
NC score	0.051557 (rank : 349)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	267	Target Neighborhood Hits	1025	Shared Neighborhood Hits	122
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

IWS1_MOUSE
NC score	0.050898 (rank : 350)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	267	Target Neighborhood Hits	1258	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CGRF1_HUMAN
NC score	0.046809 (rank : 351)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	267	Target Neighborhood Hits	51	Shared Neighborhood Hits	32
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

SYCP2_HUMAN
NC score	0.035977 (rank : 352)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	267	Target Neighborhood Hits	230	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

PIN1_MOUSE
NC score	0.034409 (rank : 353)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	267	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QUR7, Q543B3	Gene names	Pin1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

DEK_HUMAN
NC score	0.031671 (rank : 354)	θ value	1.38821 (rank : 202)
Query Neighborhood Hits	267	Target Neighborhood Hits	199	Shared Neighborhood Hits	6
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

DTX2_HUMAN
NC score	0.030694 (rank : 355)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	267	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UW9, Q96H69, Q9H890, Q9P200	Gene names	DTX2, KIAA1528
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (hDTX2).

I20L2_HUMAN
NC score	0.030285 (rank : 356)	θ value	0.279714 (rank : 162)
Query Neighborhood Hits	267	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9L3, Q64KA2	Gene names	ISG20L2
Domain Architecture
Description	Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-).

PIN1_HUMAN
NC score	0.029040 (rank : 357)	θ value	5.27518 (rank : 244)
Query Neighborhood Hits	267	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

ST18_HUMAN
NC score	0.023910 (rank : 358)	θ value	0.813845 (rank : 189)
Query Neighborhood Hits	267	Target Neighborhood Hits	252	Shared Neighborhood Hits	9
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

DTX1_HUMAN
NC score	0.023662 (rank : 359)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	267	Target Neighborhood Hits	80	Shared Neighborhood Hits	14
SwissProt Accessions	Q86Y01, O60630, Q9BS04	Gene names	DTX1
Domain Architecture
Description	Protein deltex-1 (Deltex-1) (Deltex1) (hDTX1).

UB7I1_HUMAN
NC score	0.021261 (rank : 360)	θ value	5.27518 (rank : 245)
Query Neighborhood Hits	267	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
NC score	0.020495 (rank : 361)	θ value	5.27518 (rank : 246)
Query Neighborhood Hits	267	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

MYT1_HUMAN
NC score	0.018998 (rank : 362)	θ value	1.81305 (rank : 212)
Query Neighborhood Hits	267	Target Neighborhood Hits	475	Shared Neighborhood Hits	9
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYT1_MOUSE
NC score	0.016938 (rank : 363)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	267	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

MYCB2_MOUSE
NC score	0.016143 (rank : 364)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	267	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_HUMAN
NC score	0.016006 (rank : 365)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	267	Target Neighborhood Hits	390	Shared Neighborhood Hits	25
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MAGI2_HUMAN
NC score	0.013353 (rank : 366)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	267	Target Neighborhood Hits	373	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
NC score	0.012418 (rank : 367)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	267	Target Neighborhood Hits	370	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

SEC62_HUMAN
NC score	0.011804 (rank : 368)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	267	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

K0776_HUMAN
NC score	0.009257 (rank : 369)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	267	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	O94874, Q8N765, Q9NTQ0	Gene names	KIAA0776
Domain Architecture	No domain graphic available
Description	Protein KIAA0776.

FXR1_HUMAN
NC score	0.007757 (rank : 370)	θ value	4.03905 (rank : 232)
Query Neighborhood Hits	267	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51114, Q7Z450, Q8N6R8	Gene names	FXR1
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 1 (hFXR1P).

ABC8B_MOUSE
NC score	0.000009 (rank : 371)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	267	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

CTRO_MOUSE
NC score	-0.001349 (rank : 372)	θ value	3.0926 (rank : 224)
Query Neighborhood Hits	267	Target Neighborhood Hits	2344	Shared Neighborhood Hits	54
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_HUMAN
NC score	-0.003991 (rank : 373)	θ value	4.03905 (rank : 231)
Query Neighborhood Hits	267	Target Neighborhood Hits	2092	Shared Neighborhood Hits	39
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SLIT3_MOUSE
NC score	-0.005232 (rank : 374)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	267	Target Neighborhood Hits	700	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).