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Network neighborhood for query Sequence : TRI35_HUMAN

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TRI35_HUMAN
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRI35_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	382	Target Neighborhood Hits	382	Shared Neighborhood Hits	382
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	0 (rank : 2)	NC score	0.977287 (rank : 2)
Query Neighborhood Hits	382	Target Neighborhood Hits	465	Shared Neighborhood Hits	303
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI11_HUMAN
θ value	1.91031e-50 (rank : 3)	NC score	0.939505 (rank : 5)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	234
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	5.20228e-48 (rank : 4)	NC score	0.939565 (rank : 4)
Query Neighborhood Hits	382	Target Neighborhood Hits	329	Shared Neighborhood Hits	239
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

RO52_HUMAN
θ value	4.86918e-46 (rank : 5)	NC score	0.927984 (rank : 12)
Query Neighborhood Hits	382	Target Neighborhood Hits	419	Shared Neighborhood Hits	272
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI39_MOUSE
θ value	2.41655e-45 (rank : 6)	NC score	0.923778 (rank : 18)
Query Neighborhood Hits	382	Target Neighborhood Hits	691	Shared Neighborhood Hits	300
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI60_HUMAN
θ value	1.56636e-44 (rank : 7)	NC score	0.941286 (rank : 3)
Query Neighborhood Hits	382	Target Neighborhood Hits	357	Shared Neighborhood Hits	257
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI27_HUMAN
θ value	3.48949e-44 (rank : 8)	NC score	0.924828 (rank : 17)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	224
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI62_HUMAN
θ value	7.77379e-44 (rank : 9)	NC score	0.905198 (rank : 34)
Query Neighborhood Hits	382	Target Neighborhood Hits	584	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	7.77379e-44 (rank : 10)	NC score	0.913971 (rank : 27)
Query Neighborhood Hits	382	Target Neighborhood Hits	478	Shared Neighborhood Hits	253
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI27_MOUSE
θ value	1.01529e-43 (rank : 11)	NC score	0.922185 (rank : 21)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	214
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI68_MOUSE
θ value	1.32601e-43 (rank : 12)	NC score	0.926460 (rank : 15)
Query Neighborhood Hits	382	Target Neighborhood Hits	356	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI39_HUMAN
θ value	1.73182e-43 (rank : 13)	NC score	0.922500 (rank : 20)
Query Neighborhood Hits	382	Target Neighborhood Hits	693	Shared Neighborhood Hits	304
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM7_MOUSE
θ value	6.58091e-43 (rank : 14)	NC score	0.928476 (rank : 10)
Query Neighborhood Hits	382	Target Neighborhood Hits	358	Shared Neighborhood Hits	236
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM7_HUMAN
θ value	8.04462e-41 (rank : 15)	NC score	0.928200 (rank : 11)
Query Neighborhood Hits	382	Target Neighborhood Hits	336	Shared Neighborhood Hits	233
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI68_HUMAN
θ value	1.79215e-40 (rank : 16)	NC score	0.925925 (rank : 16)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	220
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

RO52_MOUSE
θ value	2.58786e-39 (rank : 17)	NC score	0.928732 (rank : 9)
Query Neighborhood Hits	382	Target Neighborhood Hits	360	Shared Neighborhood Hits	252
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI60_MOUSE
θ value	5.76516e-39 (rank : 18)	NC score	0.927578 (rank : 13)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	201
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI50_HUMAN
θ value	9.83387e-39 (rank : 19)	NC score	0.914451 (rank : 26)
Query Neighborhood Hits	382	Target Neighborhood Hits	294	Shared Neighborhood Hits	233
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI17_MOUSE
θ value	8.32485e-38 (rank : 20)	NC score	0.910822 (rank : 29)
Query Neighborhood Hits	382	Target Neighborhood Hits	620	Shared Neighborhood Hits	269
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI17_HUMAN
θ value	5.39604e-37 (rank : 21)	NC score	0.932665 (rank : 7)
Query Neighborhood Hits	382	Target Neighborhood Hits	318	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI50_MOUSE
θ value	1.57e-36 (rank : 22)	NC score	0.915918 (rank : 24)
Query Neighborhood Hits	382	Target Neighborhood Hits	326	Shared Neighborhood Hits	243
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI10_HUMAN
θ value	1.9192e-34 (rank : 23)	NC score	0.929209 (rank : 8)
Query Neighborhood Hits	382	Target Neighborhood Hits	315	Shared Neighborhood Hits	241
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	2.12192e-33 (rank : 24)	NC score	0.927487 (rank : 14)
Query Neighborhood Hits	382	Target Neighborhood Hits	285	Shared Neighborhood Hits	235
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI38_HUMAN
θ value	2.12192e-33 (rank : 25)	NC score	0.917257 (rank : 23)
Query Neighborhood Hits	382	Target Neighborhood Hits	373	Shared Neighborhood Hits	235
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRIM6_HUMAN
θ value	6.17384e-33 (rank : 26)	NC score	0.910975 (rank : 28)
Query Neighborhood Hits	382	Target Neighborhood Hits	412	Shared Neighborhood Hits	248
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI41_HUMAN
θ value	3.06405e-32 (rank : 27)	NC score	0.906625 (rank : 32)
Query Neighborhood Hits	382	Target Neighborhood Hits	349	Shared Neighborhood Hits	220
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM4_HUMAN
θ value	1.16434e-31 (rank : 28)	NC score	0.935208 (rank : 6)
Query Neighborhood Hits	382	Target Neighborhood Hits	321	Shared Neighborhood Hits	236
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM6_MOUSE
θ value	2.86786e-30 (rank : 29)	NC score	0.909654 (rank : 30)
Query Neighborhood Hits	382	Target Neighborhood Hits	451	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI43_HUMAN
θ value	6.38894e-30 (rank : 30)	NC score	0.923708 (rank : 19)
Query Neighborhood Hits	382	Target Neighborhood Hits	341	Shared Neighborhood Hits	239
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI34_MOUSE
θ value	2.42779e-29 (rank : 31)	NC score	0.887700 (rank : 38)
Query Neighborhood Hits	382	Target Neighborhood Hits	332	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI22_HUMAN
θ value	4.14116e-29 (rank : 32)	NC score	0.905457 (rank : 33)
Query Neighborhood Hits	382	Target Neighborhood Hits	396	Shared Neighborhood Hits	252
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI15_HUMAN
θ value	5.40856e-29 (rank : 33)	NC score	0.902954 (rank : 35)
Query Neighborhood Hits	382	Target Neighborhood Hits	395	Shared Neighborhood Hits	235
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI26_MOUSE
θ value	5.40856e-29 (rank : 34)	NC score	0.915682 (rank : 25)
Query Neighborhood Hits	382	Target Neighborhood Hits	339	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI26_HUMAN
θ value	9.2256e-29 (rank : 35)	NC score	0.919470 (rank : 22)
Query Neighborhood Hits	382	Target Neighborhood Hits	335	Shared Neighborhood Hits	246
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRIM5_HUMAN
θ value	1.47289e-26 (rank : 36)	NC score	0.907990 (rank : 31)
Query Neighborhood Hits	382	Target Neighborhood Hits	424	Shared Neighborhood Hits	254
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI34_HUMAN
θ value	6.18819e-25 (rank : 37)	NC score	0.889787 (rank : 37)
Query Neighborhood Hits	382	Target Neighborhood Hits	416	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI30_MOUSE
θ value	1.05554e-24 (rank : 38)	NC score	0.900519 (rank : 36)
Query Neighborhood Hits	382	Target Neighborhood Hits	434	Shared Neighborhood Hits	252
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

MEFV_HUMAN
θ value	1.80048e-24 (rank : 39)	NC score	0.840716 (rank : 43)
Query Neighborhood Hits	382	Target Neighborhood Hits	431	Shared Neighborhood Hits	144
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI49_HUMAN
θ value	3.51386e-20 (rank : 40)	NC score	0.886658 (rank : 39)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI31_HUMAN
θ value	3.88503e-19 (rank : 41)	NC score	0.875306 (rank : 40)
Query Neighborhood Hits	382	Target Neighborhood Hits	299	Shared Neighborhood Hits	225
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

BT3A3_HUMAN
θ value	6.62687e-19 (rank : 42)	NC score	0.709792 (rank : 68)
Query Neighborhood Hits	382	Target Neighborhood Hits	233	Shared Neighborhood Hits	80
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT1A1_HUMAN
θ value	3.28887e-18 (rank : 43)	NC score	0.700814 (rank : 74)
Query Neighborhood Hits	382	Target Neighborhood Hits	322	Shared Neighborhood Hits	80
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRI73_HUMAN
θ value	4.29542e-18 (rank : 44)	NC score	0.836481 (rank : 46)
Query Neighborhood Hits	382	Target Neighborhood Hits	258	Shared Neighborhood Hits	213
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI12_MOUSE
θ value	5.60996e-18 (rank : 45)	NC score	0.858344 (rank : 42)
Query Neighborhood Hits	382	Target Neighborhood Hits	387	Shared Neighborhood Hits	224
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI74_HUMAN
θ value	9.56915e-18 (rank : 46)	NC score	0.833503 (rank : 47)
Query Neighborhood Hits	382	Target Neighborhood Hits	249	Shared Neighborhood Hits	207
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

BTNL9_HUMAN
θ value	2.13179e-17 (rank : 47)	NC score	0.717550 (rank : 65)
Query Neighborhood Hits	382	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT2A2_HUMAN
θ value	1.16975e-15 (rank : 48)	NC score	0.715561 (rank : 66)
Query Neighborhood Hits	382	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

TRI48_HUMAN
θ value	5.8054e-15 (rank : 49)	NC score	0.864778 (rank : 41)
Query Neighborhood Hits	382	Target Neighborhood Hits	192	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RFPL2_HUMAN
θ value	1.29331e-14 (rank : 50)	NC score	0.788750 (rank : 52)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

BSPRY_MOUSE
θ value	2.20605e-14 (rank : 51)	NC score	0.725564 (rank : 63)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	100
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

ERMAP_HUMAN
θ value	2.20605e-14 (rank : 52)	NC score	0.771544 (rank : 56)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	79
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI65_MOUSE
θ value	2.20605e-14 (rank : 53)	NC score	0.816272 (rank : 49)
Query Neighborhood Hits	382	Target Neighborhood Hits	340	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

BT1A1_MOUSE
θ value	3.76295e-14 (rank : 54)	NC score	0.707043 (rank : 69)
Query Neighborhood Hits	382	Target Neighborhood Hits	252	Shared Neighborhood Hits	80
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
θ value	6.41864e-14 (rank : 55)	NC score	0.704804 (rank : 70)
Query Neighborhood Hits	382	Target Neighborhood Hits	229	Shared Neighborhood Hits	82
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT2A1_HUMAN
θ value	2.43908e-13 (rank : 56)	NC score	0.702233 (rank : 71)
Query Neighborhood Hits	382	Target Neighborhood Hits	185	Shared Neighborhood Hits	79
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRI59_HUMAN
θ value	3.18553e-13 (rank : 57)	NC score	0.754664 (rank : 58)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	215
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

ERMAP_MOUSE
θ value	9.26847e-13 (rank : 58)	NC score	0.734811 (rank : 62)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI25_HUMAN
θ value	9.26847e-13 (rank : 59)	NC score	0.741945 (rank : 60)
Query Neighborhood Hits	382	Target Neighborhood Hits	472	Shared Neighborhood Hits	265
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI59_MOUSE
θ value	2.0648e-12 (rank : 60)	NC score	0.754932 (rank : 57)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	211
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

RFPL1_HUMAN
θ value	2.69671e-12 (rank : 61)	NC score	0.786110 (rank : 53)
Query Neighborhood Hits	382	Target Neighborhood Hits	119	Shared Neighborhood Hits	107
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL3_HUMAN
θ value	3.52202e-12 (rank : 62)	NC score	0.794426 (rank : 51)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	119
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

TRI13_HUMAN
θ value	3.52202e-12 (rank : 63)	NC score	0.782355 (rank : 55)
Query Neighborhood Hits	382	Target Neighborhood Hits	274	Shared Neighborhood Hits	211
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI13_MOUSE
θ value	3.52202e-12 (rank : 64)	NC score	0.785109 (rank : 54)
Query Neighborhood Hits	382	Target Neighborhood Hits	282	Shared Neighborhood Hits	214
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI65_HUMAN
θ value	1.33837e-11 (rank : 65)	NC score	0.828909 (rank : 48)
Query Neighborhood Hits	382	Target Neighborhood Hits	330	Shared Neighborhood Hits	241
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI25_MOUSE
θ value	2.98157e-11 (rank : 66)	NC score	0.746182 (rank : 59)
Query Neighborhood Hits	382	Target Neighborhood Hits	446	Shared Neighborhood Hits	258
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRIM8_HUMAN
θ value	2.98157e-11 (rank : 67)	NC score	0.701472 (rank : 72)
Query Neighborhood Hits	382	Target Neighborhood Hits	650	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

RNF39_HUMAN
θ value	1.133e-10 (rank : 68)	NC score	0.839534 (rank : 44)
Query Neighborhood Hits	382	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRIM8_MOUSE
θ value	1.47974e-10 (rank : 69)	NC score	0.700976 (rank : 73)
Query Neighborhood Hits	382	Target Neighborhood Hits	674	Shared Neighborhood Hits	256
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BSPRY_HUMAN
θ value	5.62301e-10 (rank : 70)	NC score	0.714659 (rank : 67)
Query Neighborhood Hits	382	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI52_HUMAN
θ value	5.62301e-10 (rank : 71)	NC score	0.839385 (rank : 45)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	191
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

BT2A3_HUMAN
θ value	7.34386e-10 (rank : 72)	NC score	0.697828 (rank : 76)
Query Neighborhood Hits	382	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL8_HUMAN
θ value	7.34386e-10 (rank : 73)	NC score	0.681232 (rank : 77)
Query Neighborhood Hits	382	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRIM3_MOUSE
θ value	7.34386e-10 (rank : 74)	NC score	0.613937 (rank : 94)
Query Neighborhood Hits	382	Target Neighborhood Hits	351	Shared Neighborhood Hits	210
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

BTNL3_HUMAN
θ value	1.63604e-09 (rank : 75)	NC score	0.698711 (rank : 75)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI40_HUMAN
θ value	2.79066e-09 (rank : 76)	NC score	0.803551 (rank : 50)
Query Neighborhood Hits	382	Target Neighborhood Hits	279	Shared Neighborhood Hits	194
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM3_HUMAN
θ value	6.21693e-09 (rank : 77)	NC score	0.610894 (rank : 95)
Query Neighborhood Hits	382	Target Neighborhood Hits	357	Shared Neighborhood Hits	214
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI63_HUMAN
θ value	8.11959e-09 (rank : 78)	NC score	0.634646 (rank : 85)
Query Neighborhood Hits	382	Target Neighborhood Hits	298	Shared Neighborhood Hits	177
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRIM2_HUMAN
θ value	8.11959e-09 (rank : 79)	NC score	0.606204 (rank : 97)
Query Neighborhood Hits	382	Target Neighborhood Hits	330	Shared Neighborhood Hits	217
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI18_HUMAN
θ value	1.38499e-08 (rank : 80)	NC score	0.648018 (rank : 80)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	213
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRIM1_MOUSE
θ value	1.38499e-08 (rank : 81)	NC score	0.615239 (rank : 93)
Query Neighborhood Hits	382	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

MEFV_MOUSE
θ value	1.80886e-08 (rank : 82)	NC score	0.666720 (rank : 78)
Query Neighborhood Hits	382	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRIM2_MOUSE
θ value	3.08544e-08 (rank : 83)	NC score	0.604126 (rank : 99)
Query Neighborhood Hits	382	Target Neighborhood Hits	331	Shared Neighborhood Hits	215
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI18_MOUSE
θ value	5.26297e-08 (rank : 84)	NC score	0.634347 (rank : 86)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	215
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

BFAR_MOUSE
θ value	1.99992e-07 (rank : 85)	NC score	0.576192 (rank : 105)
Query Neighborhood Hits	382	Target Neighborhood Hits	232	Shared Neighborhood Hits	170
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI37_HUMAN
θ value	1.99992e-07 (rank : 86)	NC score	0.583271 (rank : 102)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	178
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	1.99992e-07 (rank : 87)	NC score	0.583292 (rank : 101)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	181
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI32_MOUSE
θ value	2.61198e-07 (rank : 88)	NC score	0.625717 (rank : 88)
Query Neighborhood Hits	382	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI47_MOUSE
θ value	2.61198e-07 (rank : 89)	NC score	0.658716 (rank : 79)
Query Neighborhood Hits	382	Target Neighborhood Hits	295	Shared Neighborhood Hits	208
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI47_HUMAN
θ value	3.41135e-07 (rank : 90)	NC score	0.646741 (rank : 81)
Query Neighborhood Hits	382	Target Neighborhood Hits	286	Shared Neighborhood Hits	209
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI63_MOUSE
θ value	4.45536e-07 (rank : 91)	NC score	0.637183 (rank : 83)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI54_HUMAN
θ value	5.81887e-07 (rank : 92)	NC score	0.607067 (rank : 96)
Query Neighborhood Hits	382	Target Neighborhood Hits	209	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM1_HUMAN
θ value	5.81887e-07 (rank : 93)	NC score	0.616434 (rank : 91)
Query Neighborhood Hits	382	Target Neighborhood Hits	345	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI54_MOUSE
θ value	7.59969e-07 (rank : 94)	NC score	0.604181 (rank : 98)
Query Neighborhood Hits	382	Target Neighborhood Hits	197	Shared Neighborhood Hits	158
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI32_HUMAN
θ value	1.69304e-06 (rank : 95)	NC score	0.629365 (rank : 87)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

BFAR_HUMAN
θ value	2.88788e-06 (rank : 96)	NC score	0.583090 (rank : 103)
Query Neighborhood Hits	382	Target Neighborhood Hits	222	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

CHFR_MOUSE
θ value	2.88788e-06 (rank : 97)	NC score	0.440419 (rank : 135)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_HUMAN
θ value	3.77169e-06 (rank : 98)	NC score	0.447151 (rank : 131)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI16_HUMAN
θ value	4.92598e-06 (rank : 99)	NC score	0.641953 (rank : 82)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	130
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

RN169_HUMAN
θ value	1.87187e-05 (rank : 100)	NC score	0.425480 (rank : 139)
Query Neighborhood Hits	382	Target Neighborhood Hits	203	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RNF8_HUMAN
θ value	1.87187e-05 (rank : 101)	NC score	0.499234 (rank : 118)
Query Neighborhood Hits	382	Target Neighborhood Hits	622	Shared Neighborhood Hits	261
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	1.87187e-05 (rank : 102)	NC score	0.519628 (rank : 117)
Query Neighborhood Hits	382	Target Neighborhood Hits	618	Shared Neighborhood Hits	267
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

PZRN3_MOUSE
θ value	2.44474e-05 (rank : 103)	NC score	0.254133 (rank : 190)
Query Neighborhood Hits	382	Target Neighborhood Hits	447	Shared Neighborhood Hits	183
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

BRCA1_HUMAN
θ value	5.44631e-05 (rank : 104)	NC score	0.541728 (rank : 109)
Query Neighborhood Hits	382	Target Neighborhood Hits	381	Shared Neighborhood Hits	199
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	5.44631e-05 (rank : 105)	NC score	0.530287 (rank : 114)
Query Neighborhood Hits	382	Target Neighborhood Hits	436	Shared Neighborhood Hits	193
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

PZRN3_HUMAN
θ value	5.44631e-05 (rank : 106)	NC score	0.250014 (rank : 196)
Query Neighborhood Hits	382	Target Neighborhood Hits	461	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RING1_HUMAN
θ value	9.29e-05 (rank : 107)	NC score	0.473452 (rank : 126)
Query Neighborhood Hits	382	Target Neighborhood Hits	219	Shared Neighborhood Hits	160
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	9.29e-05 (rank : 108)	NC score	0.466059 (rank : 127)
Query Neighborhood Hits	382	Target Neighborhood Hits	220	Shared Neighborhood Hits	161
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RAD18_MOUSE
θ value	0.000158464 (rank : 109)	NC score	0.396980 (rank : 145)
Query Neighborhood Hits	382	Target Neighborhood Hits	230	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

TRAIP_MOUSE
θ value	0.000158464 (rank : 110)	NC score	0.197819 (rank : 215)
Query Neighborhood Hits	382	Target Neighborhood Hits	745	Shared Neighborhood Hits	166
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

ARD1_MOUSE
θ value	0.00020696 (rank : 111)	NC score	0.152267 (rank : 240)
Query Neighborhood Hits	382	Target Neighborhood Hits	573	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

RAG1_HUMAN
θ value	0.00020696 (rank : 112)	NC score	0.439189 (rank : 136)
Query Neighborhood Hits	382	Target Neighborhood Hits	203	Shared Neighborhood Hits	143
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RBBP6_HUMAN
θ value	0.00020696 (rank : 113)	NC score	0.203401 (rank : 210)
Query Neighborhood Hits	382	Target Neighborhood Hits	1135	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	0.00020696 (rank : 114)	NC score	0.222859 (rank : 202)
Query Neighborhood Hits	382	Target Neighborhood Hits	1014	Shared Neighborhood Hits	165
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRAIP_HUMAN
θ value	0.00020696 (rank : 115)	NC score	0.214248 (rank : 203)
Query Neighborhood Hits	382	Target Neighborhood Hits	780	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRI44_HUMAN
θ value	0.00020696 (rank : 116)	NC score	0.571899 (rank : 106)
Query Neighborhood Hits	382	Target Neighborhood Hits	393	Shared Neighborhood Hits	118
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI55_HUMAN
θ value	0.00020696 (rank : 117)	NC score	0.617988 (rank : 90)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TIF1G_MOUSE
θ value	0.000270298 (rank : 118)	NC score	0.292154 (rank : 174)
Query Neighborhood Hits	382	Target Neighborhood Hits	498	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

DTX3_MOUSE
θ value	0.00035302 (rank : 119)	NC score	0.372341 (rank : 149)
Query Neighborhood Hits	382	Target Neighborhood Hits	202	Shared Neighborhood Hits	153
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RAG1_MOUSE
θ value	0.00035302 (rank : 120)	NC score	0.424936 (rank : 140)
Query Neighborhood Hits	382	Target Neighborhood Hits	189	Shared Neighborhood Hits	146
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RN125_MOUSE
θ value	0.00035302 (rank : 121)	NC score	0.537672 (rank : 111)
Query Neighborhood Hits	382	Target Neighborhood Hits	220	Shared Neighborhood Hits	166
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
θ value	0.00035302 (rank : 122)	NC score	0.537186 (rank : 112)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	174
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	0.00035302 (rank : 123)	NC score	0.532450 (rank : 113)
Query Neighborhood Hits	382	Target Neighborhood Hits	248	Shared Neighborhood Hits	180
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

ARD1_HUMAN
θ value	0.000461057 (rank : 124)	NC score	0.148034 (rank : 242)
Query Neighborhood Hits	382	Target Neighborhood Hits	621	Shared Neighborhood Hits	83
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

CAF1A_MOUSE
θ value	0.000461057 (rank : 125)	NC score	0.075102 (rank : 323)
Query Neighborhood Hits	382	Target Neighborhood Hits	736	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DTX3_HUMAN
θ value	0.000461057 (rank : 126)	NC score	0.363603 (rank : 151)
Query Neighborhood Hits	382	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

RAD18_HUMAN
θ value	0.000461057 (rank : 127)	NC score	0.368788 (rank : 150)
Query Neighborhood Hits	382	Target Neighborhood Hits	284	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

BARD1_MOUSE
θ value	0.000602161 (rank : 128)	NC score	0.158794 (rank : 236)
Query Neighborhood Hits	382	Target Neighborhood Hits	411	Shared Neighborhood Hits	99
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PCGF2_HUMAN
θ value	0.000602161 (rank : 129)	NC score	0.284707 (rank : 180)
Query Neighborhood Hits	382	Target Neighborhood Hits	222	Shared Neighborhood Hits	122
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	0.000602161 (rank : 130)	NC score	0.284734 (rank : 179)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	122
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRAF5_MOUSE
θ value	0.000602161 (rank : 131)	NC score	0.271569 (rank : 182)
Query Neighborhood Hits	382	Target Neighborhood Hits	355	Shared Neighborhood Hits	162
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI44_MOUSE
θ value	0.000602161 (rank : 132)	NC score	0.580669 (rank : 104)
Query Neighborhood Hits	382	Target Neighborhood Hits	327	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

UHRF1_MOUSE
θ value	0.000602161 (rank : 133)	NC score	0.289047 (rank : 178)
Query Neighborhood Hits	382	Target Neighborhood Hits	278	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

AMFR2_HUMAN
θ value	0.000786445 (rank : 134)	NC score	0.258890 (rank : 187)
Query Neighborhood Hits	382	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

PCGF4_HUMAN
θ value	0.000786445 (rank : 135)	NC score	0.291031 (rank : 176)
Query Neighborhood Hits	382	Target Neighborhood Hits	161	Shared Neighborhood Hits	127
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	0.000786445 (rank : 136)	NC score	0.291785 (rank : 175)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

UHRF2_MOUSE
θ value	0.000786445 (rank : 137)	NC score	0.337993 (rank : 157)
Query Neighborhood Hits	382	Target Neighborhood Hits	275	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN313_MOUSE
θ value	0.000786445 (rank : 138)	NC score	0.552881 (rank : 107)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	194
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

AMFR_MOUSE
θ value	0.00102713 (rank : 139)	NC score	0.257102 (rank : 188)
Query Neighborhood Hits	382	Target Neighborhood Hits	208	Shared Neighborhood Hits	138
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TIF1G_HUMAN
θ value	0.00102713 (rank : 140)	NC score	0.296236 (rank : 173)
Query Neighborhood Hits	382	Target Neighborhood Hits	410	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI14_MOUSE
θ value	0.00102713 (rank : 141)	NC score	0.736641 (rank : 61)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

UHRF2_HUMAN
θ value	0.00102713 (rank : 142)	NC score	0.342341 (rank : 156)
Query Neighborhood Hits	382	Target Neighborhood Hits	269	Shared Neighborhood Hits	167
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BARD1_HUMAN
θ value	0.00134147 (rank : 143)	NC score	0.161990 (rank : 235)
Query Neighborhood Hits	382	Target Neighborhood Hits	427	Shared Neighborhood Hits	107
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

RING2_HUMAN
θ value	0.00175202 (rank : 144)	NC score	0.441084 (rank : 134)
Query Neighborhood Hits	382	Target Neighborhood Hits	201	Shared Neighborhood Hits	157
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.00175202 (rank : 145)	NC score	0.441156 (rank : 133)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

ZN313_HUMAN
θ value	0.00175202 (rank : 146)	NC score	0.539372 (rank : 110)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RFWD2_HUMAN
θ value	0.00228821 (rank : 147)	NC score	0.321330 (rank : 163)
Query Neighborhood Hits	382	Target Neighborhood Hits	518	Shared Neighborhood Hits	193
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	0.00228821 (rank : 148)	NC score	0.321516 (rank : 162)
Query Neighborhood Hits	382	Target Neighborhood Hits	535	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TRI56_MOUSE
θ value	0.00228821 (rank : 149)	NC score	0.477236 (rank : 125)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

BRAP_HUMAN
θ value	0.00298849 (rank : 150)	NC score	0.141904 (rank : 249)
Query Neighborhood Hits	382	Target Neighborhood Hits	560	Shared Neighborhood Hits	145
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RNF13_HUMAN
θ value	0.00298849 (rank : 151)	NC score	0.137629 (rank : 251)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	78
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RN185_HUMAN
θ value	0.00390308 (rank : 152)	NC score	0.437189 (rank : 137)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	172
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	0.00390308 (rank : 153)	NC score	0.436267 (rank : 138)
Query Neighborhood Hits	382	Target Neighborhood Hits	211	Shared Neighborhood Hits	172
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

TRAF5_HUMAN
θ value	0.00390308 (rank : 154)	NC score	0.248478 (rank : 198)
Query Neighborhood Hits	382	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

RN125_HUMAN
θ value	0.00509761 (rank : 155)	NC score	0.528580 (rank : 115)
Query Neighborhood Hits	382	Target Neighborhood Hits	230	Shared Neighborhood Hits	175
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF38_HUMAN
θ value	0.00509761 (rank : 156)	NC score	0.122884 (rank : 263)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

RNF38_MOUSE
θ value	0.00509761 (rank : 157)	NC score	0.120674 (rank : 265)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

SMRA3_HUMAN
θ value	0.00665767 (rank : 158)	NC score	0.310546 (rank : 167)
Query Neighborhood Hits	382	Target Neighborhood Hits	265	Shared Neighborhood Hits	185
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI56_HUMAN
θ value	0.00665767 (rank : 159)	NC score	0.479382 (rank : 124)
Query Neighborhood Hits	382	Target Neighborhood Hits	339	Shared Neighborhood Hits	188
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

RNF13_MOUSE
θ value	0.00869519 (rank : 160)	NC score	0.132842 (rank : 255)
Query Neighborhood Hits	382	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

SPRY4_MOUSE
θ value	0.00869519 (rank : 161)	NC score	0.616224 (rank : 92)
Query Neighborhood Hits	382	Target Neighborhood Hits	82	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

ZN179_HUMAN
θ value	0.00869519 (rank : 162)	NC score	0.623932 (rank : 89)
Query Neighborhood Hits	382	Target Neighborhood Hits	178	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

RN167_HUMAN
θ value	0.0113563 (rank : 163)	NC score	0.140841 (rank : 250)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	0.0113563 (rank : 164)	NC score	0.145670 (rank : 245)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	88
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

SMC3_HUMAN
θ value	0.0113563 (rank : 165)	NC score	0.057368 (rank : 391)
Query Neighborhood Hits	382	Target Neighborhood Hits	1186	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	0.0113563 (rank : 166)	NC score	0.057397 (rank : 389)
Query Neighborhood Hits	382	Target Neighborhood Hits	1187	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

GOGB1_HUMAN
θ value	0.0148317 (rank : 167)	NC score	0.076396 (rank : 320)
Query Neighborhood Hits	382	Target Neighborhood Hits	2297	Shared Neighborhood Hits	190
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

R113A_HUMAN
θ value	0.0193708 (rank : 168)	NC score	0.301266 (rank : 170)
Query Neighborhood Hits	382	Target Neighborhood Hits	177	Shared Neighborhood Hits	129
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

ERC2_HUMAN
θ value	0.0252991 (rank : 169)	NC score	0.053573 (rank : 414)
Query Neighborhood Hits	382	Target Neighborhood Hits	1156	Shared Neighborhood Hits	118
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	0.0252991 (rank : 170)	NC score	0.052811 (rank : 422)
Query Neighborhood Hits	382	Target Neighborhood Hits	1166	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

MYLIP_HUMAN
θ value	0.0252991 (rank : 171)	NC score	0.080725 (rank : 315)
Query Neighborhood Hits	382	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PML_HUMAN
θ value	0.0252991 (rank : 172)	NC score	0.324791 (rank : 160)
Query Neighborhood Hits	382	Target Neighborhood Hits	248	Shared Neighborhood Hits	123
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	0.0252991 (rank : 173)	NC score	0.301116 (rank : 171)
Query Neighborhood Hits	382	Target Neighborhood Hits	246	Shared Neighborhood Hits	135
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRAF7_HUMAN
θ value	0.0252991 (rank : 174)	NC score	0.208789 (rank : 205)
Query Neighborhood Hits	382	Target Neighborhood Hits	482	Shared Neighborhood Hits	164
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	0.0252991 (rank : 175)	NC score	0.208169 (rank : 206)
Query Neighborhood Hits	382	Target Neighborhood Hits	470	Shared Neighborhood Hits	161
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI36_HUMAN
θ value	0.0252991 (rank : 176)	NC score	0.450201 (rank : 129)
Query Neighborhood Hits	382	Target Neighborhood Hits	282	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

UHRF1_HUMAN
θ value	0.0252991 (rank : 177)	NC score	0.276538 (rank : 181)
Query Neighborhood Hits	382	Target Neighborhood Hits	272	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

DTX3L_HUMAN
θ value	0.0330416 (rank : 178)	NC score	0.212100 (rank : 204)
Query Neighborhood Hits	382	Target Neighborhood Hits	187	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

RN168_HUMAN
θ value	0.0330416 (rank : 179)	NC score	0.524244 (rank : 116)
Query Neighborhood Hits	382	Target Neighborhood Hits	370	Shared Neighborhood Hits	201
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF41_HUMAN
θ value	0.0330416 (rank : 180)	NC score	0.423466 (rank : 142)
Query Neighborhood Hits	382	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	0.0330416 (rank : 181)	NC score	0.423558 (rank : 141)
Query Neighborhood Hits	382	Target Neighborhood Hits	224	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

SKIL_HUMAN
θ value	0.0330416 (rank : 182)	NC score	0.052410 (rank : 423)
Query Neighborhood Hits	382	Target Neighborhood Hits	460	Shared Neighborhood Hits	65
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

TRI16_MOUSE
θ value	0.0330416 (rank : 183)	NC score	0.635021 (rank : 84)
Query Neighborhood Hits	382	Target Neighborhood Hits	196	Shared Neighborhood Hits	116
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

CBLC_HUMAN
θ value	0.0431538 (rank : 184)	NC score	0.205297 (rank : 208)
Query Neighborhood Hits	382	Target Neighborhood Hits	173	Shared Neighborhood Hits	142
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

MIB1_HUMAN
θ value	0.0431538 (rank : 185)	NC score	0.093870 (rank : 293)
Query Neighborhood Hits	382	Target Neighborhood Hits	470	Shared Neighborhood Hits	113
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.0431538 (rank : 186)	NC score	0.093734 (rank : 294)
Query Neighborhood Hits	382	Target Neighborhood Hits	471	Shared Neighborhood Hits	113
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PEX10_HUMAN
θ value	0.0431538 (rank : 187)	NC score	0.550316 (rank : 108)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	196
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

RNF5_MOUSE
θ value	0.0431538 (rank : 188)	NC score	0.411781 (rank : 144)
Query Neighborhood Hits	382	Target Neighborhood Hits	206	Shared Neighborhood Hits	162
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

TIF1B_MOUSE
θ value	0.0431538 (rank : 189)	NC score	0.261373 (rank : 186)
Query Neighborhood Hits	382	Target Neighborhood Hits	276	Shared Neighborhood Hits	113
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RNF5_HUMAN
θ value	0.0563607 (rank : 190)	NC score	0.412595 (rank : 143)
Query Neighborhood Hits	382	Target Neighborhood Hits	206	Shared Neighborhood Hits	162
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI46_HUMAN
θ value	0.0563607 (rank : 191)	NC score	0.481364 (rank : 123)
Query Neighborhood Hits	382	Target Neighborhood Hits	291	Shared Neighborhood Hits	194
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0.0563607 (rank : 192)	NC score	0.482294 (rank : 122)
Query Neighborhood Hits	382	Target Neighborhood Hits	287	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

CBLC_MOUSE
θ value	0.0736092 (rank : 193)	NC score	0.206117 (rank : 207)
Query Neighborhood Hits	382	Target Neighborhood Hits	186	Shared Neighborhood Hits	147
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

MYLIP_MOUSE
θ value	0.0736092 (rank : 194)	NC score	0.059178 (rank : 370)
Query Neighborhood Hits	382	Target Neighborhood Hits	139	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PCGF6_HUMAN
θ value	0.0736092 (rank : 195)	NC score	0.310602 (rank : 166)
Query Neighborhood Hits	382	Target Neighborhood Hits	178	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	0.0736092 (rank : 196)	NC score	0.312398 (rank : 165)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	126
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRIM9_HUMAN
θ value	0.0736092 (rank : 197)	NC score	0.456332 (rank : 128)
Query Neighborhood Hits	382	Target Neighborhood Hits	294	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	0.0736092 (rank : 198)	NC score	0.450052 (rank : 130)
Query Neighborhood Hits	382	Target Neighborhood Hits	274	Shared Neighborhood Hits	173
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CBL_HUMAN
θ value	0.0961366 (rank : 199)	NC score	0.204649 (rank : 209)
Query Neighborhood Hits	382	Target Neighborhood Hits	353	Shared Neighborhood Hits	161
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	0.0961366 (rank : 200)	NC score	0.200574 (rank : 211)
Query Neighborhood Hits	382	Target Neighborhood Hits	426	Shared Neighborhood Hits	165
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RFFL_HUMAN
θ value	0.0961366 (rank : 201)	NC score	0.132659 (rank : 256)
Query Neighborhood Hits	382	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	0.0961366 (rank : 202)	NC score	0.129929 (rank : 259)
Query Neighborhood Hits	382	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RN168_MOUSE
θ value	0.0961366 (rank : 203)	NC score	0.496520 (rank : 120)
Query Neighborhood Hits	382	Target Neighborhood Hits	440	Shared Neighborhood Hits	218
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SKIL_MOUSE
θ value	0.0961366 (rank : 204)	NC score	0.050423 (rank : 439)
Query Neighborhood Hits	382	Target Neighborhood Hits	719	Shared Neighborhood Hits	86
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SPFH2_HUMAN
θ value	0.0961366 (rank : 205)	NC score	0.040368 (rank : 453)
Query Neighborhood Hits	382	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O94905, Q6NW21, Q86VS6, Q86W49	Gene names	SPFH2, C8orf2
Domain Architecture
Description	SPFH domain-containing protein 2 precursor.

SPRY4_HUMAN
θ value	0.0961366 (rank : 206)	NC score	0.596745 (rank : 100)
Query Neighborhood Hits	382	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TIF1B_HUMAN
θ value	0.0961366 (rank : 207)	NC score	0.265962 (rank : 185)
Query Neighborhood Hits	382	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PLEC1_HUMAN
θ value	0.125558 (rank : 208)	NC score	0.046892 (rank : 443)
Query Neighborhood Hits	382	Target Neighborhood Hits	1326	Shared Neighborhood Hits	129
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RNF19_HUMAN
θ value	0.125558 (rank : 209)	NC score	0.086396 (rank : 304)
Query Neighborhood Hits	382	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	0.125558 (rank : 210)	NC score	0.086492 (rank : 303)
Query Neighborhood Hits	382	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

SPFH2_MOUSE
θ value	0.125558 (rank : 211)	NC score	0.039441 (rank : 455)
Query Neighborhood Hits	382	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BFZ9, Q8BML8	Gene names	Spfh2
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 2 precursor.

TRAF6_HUMAN
θ value	0.125558 (rank : 212)	NC score	0.354514 (rank : 153)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	0.125558 (rank : 213)	NC score	0.363252 (rank : 152)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	165
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRI36_MOUSE
θ value	0.125558 (rank : 214)	NC score	0.441760 (rank : 132)
Query Neighborhood Hits	382	Target Neighborhood Hits	266	Shared Neighborhood Hits	174
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

BRE1B_HUMAN
θ value	0.163984 (rank : 215)	NC score	0.144326 (rank : 248)
Query Neighborhood Hits	382	Target Neighborhood Hits	1040	Shared Neighborhood Hits	232
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	0.163984 (rank : 216)	NC score	0.145455 (rank : 246)
Query Neighborhood Hits	382	Target Neighborhood Hits	970	Shared Neighborhood Hits	228
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CP250_MOUSE
θ value	0.163984 (rank : 217)	NC score	0.066703 (rank : 343)
Query Neighborhood Hits	382	Target Neighborhood Hits	1583	Shared Neighborhood Hits	158
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

LNX2_MOUSE
θ value	0.163984 (rank : 218)	NC score	0.251469 (rank : 194)
Query Neighborhood Hits	382	Target Neighborhood Hits	407	Shared Neighborhood Hits	174
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRC45_MOUSE
θ value	0.163984 (rank : 219)	NC score	0.058134 (rank : 381)
Query Neighborhood Hits	382	Target Neighborhood Hits	959	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

OPTN_MOUSE
θ value	0.163984 (rank : 220)	NC score	0.051982 (rank : 428)
Query Neighborhood Hits	382	Target Neighborhood Hits	1120	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PJA1_MOUSE
θ value	0.163984 (rank : 221)	NC score	0.130615 (rank : 258)
Query Neighborhood Hits	382	Target Neighborhood Hits	145	Shared Neighborhood Hits	74
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RN141_HUMAN
θ value	0.163984 (rank : 222)	NC score	0.353732 (rank : 154)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	151
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	0.163984 (rank : 223)	NC score	0.352834 (rank : 155)
Query Neighborhood Hits	382	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

TRAF4_MOUSE
θ value	0.163984 (rank : 224)	NC score	0.156325 (rank : 237)
Query Neighborhood Hits	382	Target Neighborhood Hits	338	Shared Neighborhood Hits	113
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

ASPP2_HUMAN
θ value	0.21417 (rank : 225)	NC score	0.033988 (rank : 463)
Query Neighborhood Hits	382	Target Neighborhood Hits	1156	Shared Neighborhood Hits	94
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

BIRC8_HUMAN
θ value	0.21417 (rank : 226)	NC score	0.152390 (rank : 239)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

RNF34_HUMAN
θ value	0.21417 (rank : 227)	NC score	0.164263 (rank : 234)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	87
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	0.21417 (rank : 228)	NC score	0.165953 (rank : 230)
Query Neighborhood Hits	382	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

SMRA3_MOUSE
θ value	0.21417 (rank : 229)	NC score	0.290990 (rank : 177)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	178
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SYCP1_MOUSE
θ value	0.21417 (rank : 230)	NC score	0.070814 (rank : 329)
Query Neighborhood Hits	382	Target Neighborhood Hits	1456	Shared Neighborhood Hits	149
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

LNX2_HUMAN
θ value	0.279714 (rank : 231)	NC score	0.250229 (rank : 195)
Query Neighborhood Hits	382	Target Neighborhood Hits	389	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

TIF1A_MOUSE
θ value	0.279714 (rank : 232)	NC score	0.176000 (rank : 228)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI29_MOUSE
θ value	0.279714 (rank : 233)	NC score	0.496742 (rank : 119)
Query Neighborhood Hits	382	Target Neighborhood Hits	306	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

BRAP_MOUSE
θ value	0.365318 (rank : 234)	NC score	0.125031 (rank : 261)
Query Neighborhood Hits	382	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRE1A_HUMAN
θ value	0.365318 (rank : 235)	NC score	0.118785 (rank : 266)
Query Neighborhood Hits	382	Target Neighborhood Hits	1071	Shared Neighborhood Hits	217
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	0.365318 (rank : 236)	NC score	0.118187 (rank : 267)
Query Neighborhood Hits	382	Target Neighborhood Hits	1025	Shared Neighborhood Hits	215
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CBLB_HUMAN
θ value	0.365318 (rank : 237)	NC score	0.198218 (rank : 214)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	154
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	0.365318 (rank : 238)	NC score	0.199243 (rank : 213)
Query Neighborhood Hits	382	Target Neighborhood Hits	277	Shared Neighborhood Hits	154
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CCD46_MOUSE
θ value	0.365318 (rank : 239)	NC score	0.065523 (rank : 351)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	150
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_HUMAN
θ value	0.365318 (rank : 240)	NC score	0.076684 (rank : 319)
Query Neighborhood Hits	382	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

NIN_HUMAN
θ value	0.365318 (rank : 241)	NC score	0.066839 (rank : 342)
Query Neighborhood Hits	382	Target Neighborhood Hits	1416	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

PEX5_HUMAN
θ value	0.365318 (rank : 242)	NC score	0.013744 (rank : 496)
Query Neighborhood Hits	382	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PJA1_HUMAN
θ value	0.365318 (rank : 243)	NC score	0.149798 (rank : 241)
Query Neighborhood Hits	382	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RILP_HUMAN
θ value	0.365318 (rank : 244)	NC score	0.041161 (rank : 451)
Query Neighborhood Hits	382	Target Neighborhood Hits	249	Shared Neighborhood Hits	41
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

RKHD1_HUMAN
θ value	0.365318 (rank : 245)	NC score	0.155408 (rank : 238)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

TIF1A_HUMAN
θ value	0.365318 (rank : 246)	NC score	0.199588 (rank : 212)
Query Neighborhood Hits	382	Target Neighborhood Hits	327	Shared Neighborhood Hits	105
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

U2AFM_MOUSE
θ value	0.365318 (rank : 247)	NC score	0.033017 (rank : 464)
Query Neighborhood Hits	382	Target Neighborhood Hits	543	Shared Neighborhood Hits	71
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

GUC2F_HUMAN
θ value	0.47712 (rank : 248)	NC score	-0.004616 (rank : 507)
Query Neighborhood Hits	382	Target Neighborhood Hits	740	Shared Neighborhood Hits	12
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

IBRD3_HUMAN
θ value	0.47712 (rank : 249)	NC score	0.060476 (rank : 367)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

IFT74_HUMAN
θ value	0.47712 (rank : 250)	NC score	0.051204 (rank : 432)
Query Neighborhood Hits	382	Target Neighborhood Hits	949	Shared Neighborhood Hits	117
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

MYO5C_HUMAN
θ value	0.47712 (rank : 251)	NC score	0.038364 (rank : 458)
Query Neighborhood Hits	382	Target Neighborhood Hits	1206	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RN123_HUMAN
θ value	0.47712 (rank : 252)	NC score	0.132922 (rank : 254)
Query Neighborhood Hits	382	Target Neighborhood Hits	175	Shared Neighborhood Hits	124
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	0.47712 (rank : 253)	NC score	0.134689 (rank : 253)
Query Neighborhood Hits	382	Target Neighborhood Hits	174	Shared Neighborhood Hits	124
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN139_MOUSE
θ value	0.47712 (rank : 254)	NC score	0.092498 (rank : 298)
Query Neighborhood Hits	382	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

TRI29_HUMAN
θ value	0.47712 (rank : 255)	NC score	0.486558 (rank : 121)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TTC3_HUMAN
θ value	0.47712 (rank : 256)	NC score	0.089701 (rank : 299)
Query Neighborhood Hits	382	Target Neighborhood Hits	664	Shared Neighborhood Hits	128
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

CD2L1_MOUSE
θ value	0.62314 (rank : 257)	NC score	-0.000959 (rank : 504)
Query Neighborhood Hits	382	Target Neighborhood Hits	1463	Shared Neighborhood Hits	76
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

R113B_HUMAN
θ value	0.62314 (rank : 258)	NC score	0.300506 (rank : 172)
Query Neighborhood Hits	382	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RN139_HUMAN
θ value	0.62314 (rank : 259)	NC score	0.093192 (rank : 296)
Query Neighborhood Hits	382	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

TRAF4_HUMAN
θ value	0.62314 (rank : 260)	NC score	0.232498 (rank : 201)
Query Neighborhood Hits	382	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRHY_HUMAN
θ value	0.62314 (rank : 261)	NC score	0.064360 (rank : 354)
Query Neighborhood Hits	382	Target Neighborhood Hits	1385	Shared Neighborhood Hits	124
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

MYH11_MOUSE
θ value	0.813845 (rank : 262)	NC score	0.050536 (rank : 438)
Query Neighborhood Hits	382	Target Neighborhood Hits	1777	Shared Neighborhood Hits	158
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PCNT_HUMAN
θ value	0.813845 (rank : 263)	NC score	0.065977 (rank : 347)
Query Neighborhood Hits	382	Target Neighborhood Hits	1551	Shared Neighborhood Hits	146
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PZRN4_HUMAN
θ value	0.813845 (rank : 264)	NC score	0.238161 (rank : 199)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	183
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

CCD22_HUMAN
θ value	1.06291 (rank : 265)	NC score	0.027809 (rank : 476)
Query Neighborhood Hits	382	Target Neighborhood Hits	242	Shared Neighborhood Hits	45
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

CCD41_MOUSE
θ value	1.06291 (rank : 266)	NC score	0.067761 (rank : 338)
Query Neighborhood Hits	382	Target Neighborhood Hits	1399	Shared Neighborhood Hits	148
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CD2L1_HUMAN
θ value	1.06291 (rank : 267)	NC score	-0.000716 (rank : 503)
Query Neighborhood Hits	382	Target Neighborhood Hits	1467	Shared Neighborhood Hits	76
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

HIC1_HUMAN
θ value	1.06291 (rank : 268)	NC score	-0.008503 (rank : 512)
Query Neighborhood Hits	382	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HIC1_MOUSE
θ value	1.06291 (rank : 269)	NC score	-0.008438 (rank : 511)
Query Neighborhood Hits	382	Target Neighborhood Hits	863	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

LNX1_MOUSE
θ value	1.06291 (rank : 270)	NC score	0.254082 (rank : 191)
Query Neighborhood Hits	382	Target Neighborhood Hits	377	Shared Neighborhood Hits	162
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

PDCD7_HUMAN
θ value	1.06291 (rank : 271)	NC score	0.027246 (rank : 479)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

SH3G1_HUMAN
θ value	1.06291 (rank : 272)	NC score	0.011680 (rank : 499)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

TARA_HUMAN
θ value	1.06291 (rank : 273)	NC score	0.027223 (rank : 480)
Query Neighborhood Hits	382	Target Neighborhood Hits	1626	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRI42_MOUSE
θ value	1.06291 (rank : 274)	NC score	0.337811 (rank : 158)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	127
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UACA_HUMAN
θ value	1.06291 (rank : 275)	NC score	0.058108 (rank : 382)
Query Neighborhood Hits	382	Target Neighborhood Hits	1622	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

BIRC7_HUMAN
θ value	1.38821 (rank : 276)	NC score	0.309858 (rank : 169)
Query Neighborhood Hits	382	Target Neighborhood Hits	185	Shared Neighborhood Hits	145
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

CCD41_HUMAN
θ value	1.38821 (rank : 277)	NC score	0.061845 (rank : 362)
Query Neighborhood Hits	382	Target Neighborhood Hits	1139	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD70_MOUSE
θ value	1.38821 (rank : 278)	NC score	0.020432 (rank : 490)
Query Neighborhood Hits	382	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9B0, Q9D9H6	Gene names	Ccdc70
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 70 precursor.

CI093_HUMAN
θ value	1.38821 (rank : 279)	NC score	0.056469 (rank : 393)
Query Neighborhood Hits	382	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_HUMAN
θ value	1.38821 (rank : 280)	NC score	0.050237 (rank : 440)
Query Neighborhood Hits	382	Target Neighborhood Hits	1275	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CROCC_MOUSE
θ value	1.38821 (rank : 281)	NC score	0.064108 (rank : 356)
Query Neighborhood Hits	382	Target Neighborhood Hits	1460	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CTRO_HUMAN
θ value	1.38821 (rank : 282)	NC score	0.017057 (rank : 491)
Query Neighborhood Hits	382	Target Neighborhood Hits	2092	Shared Neighborhood Hits	134
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	1.38821 (rank : 283)	NC score	0.020439 (rank : 489)
Query Neighborhood Hits	382	Target Neighborhood Hits	2344	Shared Neighborhood Hits	149
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GCP6_HUMAN
θ value	1.38821 (rank : 284)	NC score	0.022129 (rank : 487)
Query Neighborhood Hits	382	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

GOGA4_HUMAN
θ value	1.38821 (rank : 285)	NC score	0.065470 (rank : 353)
Query Neighborhood Hits	382	Target Neighborhood Hits	2034	Shared Neighborhood Hits	180
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

INCE_MOUSE
θ value	1.38821 (rank : 286)	NC score	0.055454 (rank : 401)
Query Neighborhood Hits	382	Target Neighborhood Hits	903	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MVP_MOUSE
θ value	1.38821 (rank : 287)	NC score	0.025691 (rank : 483)
Query Neighborhood Hits	382	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQK5	Gene names	Mvp
Domain Architecture
Description	Major vault protein (MVP).

MY18A_HUMAN
θ value	1.38821 (rank : 288)	NC score	0.057164 (rank : 392)
Query Neighborhood Hits	382	Target Neighborhood Hits	1929	Shared Neighborhood Hits	165
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RNF32_HUMAN
θ value	1.38821 (rank : 289)	NC score	0.164657 (rank : 233)
Query Neighborhood Hits	382	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

SFR17_HUMAN
θ value	1.38821 (rank : 290)	NC score	0.026719 (rank : 481)
Query Neighborhood Hits	382	Target Neighborhood Hits	325	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

ASPP1_HUMAN
θ value	1.81305 (rank : 291)	NC score	0.027406 (rank : 478)
Query Neighborhood Hits	382	Target Neighborhood Hits	956	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CD2L2_HUMAN
θ value	1.81305 (rank : 292)	NC score	-0.002269 (rank : 505)
Query Neighborhood Hits	382	Target Neighborhood Hits	1439	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CENPF_HUMAN
θ value	1.81305 (rank : 293)	NC score	0.069283 (rank : 332)
Query Neighborhood Hits	382	Target Neighborhood Hits	1932	Shared Neighborhood Hits	177
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF060_HUMAN
θ value	1.81305 (rank : 294)	NC score	0.068140 (rank : 337)
Query Neighborhood Hits	382	Target Neighborhood Hits	1270	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

GCC1_HUMAN
θ value	1.81305 (rank : 295)	NC score	0.070041 (rank : 330)
Query Neighborhood Hits	382	Target Neighborhood Hits	887	Shared Neighborhood Hits	117
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

JIP4_HUMAN
θ value	1.81305 (rank : 296)	NC score	0.030230 (rank : 472)
Query Neighborhood Hits	382	Target Neighborhood Hits	585	Shared Neighborhood Hits	80
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

MVP_HUMAN
θ value	1.81305 (rank : 297)	NC score	0.023719 (rank : 486)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q14764, Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1	Gene names	MVP, LRP
Domain Architecture
Description	Major vault protein (MVP) (Lung resistance-related protein).

SPFH1_HUMAN
θ value	1.81305 (rank : 298)	NC score	0.032359 (rank : 465)
Query Neighborhood Hits	382	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

SPSB2_MOUSE
θ value	1.81305 (rank : 299)	NC score	0.014846 (rank : 492)
Query Neighborhood Hits	382	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

TOPRS_HUMAN
θ value	1.81305 (rank : 300)	NC score	0.249612 (rank : 197)
Query Neighborhood Hits	382	Target Neighborhood Hits	286	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	1.81305 (rank : 301)	NC score	0.253061 (rank : 193)
Query Neighborhood Hits	382	Target Neighborhood Hits	263	Shared Neighborhood Hits	141
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ASPP1_MOUSE
θ value	2.36792 (rank : 302)	NC score	0.024856 (rank : 485)
Query Neighborhood Hits	382	Target Neighborhood Hits	1244	Shared Neighborhood Hits	85
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DYHC_HUMAN
θ value	2.36792 (rank : 303)	NC score	0.029657 (rank : 474)
Query Neighborhood Hits	382	Target Neighborhood Hits	733	Shared Neighborhood Hits	98
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	2.36792 (rank : 304)	NC score	0.029555 (rank : 475)
Query Neighborhood Hits	382	Target Neighborhood Hits	729	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

GOGA3_HUMAN
θ value	2.36792 (rank : 305)	NC score	0.057999 (rank : 384)
Query Neighborhood Hits	382	Target Neighborhood Hits	1317	Shared Neighborhood Hits	132
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

HIC2_HUMAN
θ value	2.36792 (rank : 306)	NC score	-0.008947 (rank : 513)
Query Neighborhood Hits	382	Target Neighborhood Hits	820	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

LRSM1_MOUSE
θ value	2.36792 (rank : 307)	NC score	0.073174 (rank : 325)
Query Neighborhood Hits	382	Target Neighborhood Hits	874	Shared Neighborhood Hits	159
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MKRN3_MOUSE
θ value	2.36792 (rank : 308)	NC score	0.068978 (rank : 333)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	67
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

MY18A_MOUSE
θ value	2.36792 (rank : 309)	NC score	0.053363 (rank : 415)
Query Neighborhood Hits	382	Target Neighborhood Hits	1989	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RNF32_MOUSE
θ value	2.36792 (rank : 310)	NC score	0.147985 (rank : 243)
Query Neighborhood Hits	382	Target Neighborhood Hits	129	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

SDCG8_HUMAN
θ value	2.36792 (rank : 311)	NC score	0.058722 (rank : 375)
Query Neighborhood Hits	382	Target Neighborhood Hits	1002	Shared Neighborhood Hits	126
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SMCA2_HUMAN
θ value	2.36792 (rank : 312)	NC score	0.010215 (rank : 501)
Query Neighborhood Hits	382	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

UACA_MOUSE
θ value	2.36792 (rank : 313)	NC score	0.044574 (rank : 446)
Query Neighborhood Hits	382	Target Neighborhood Hits	1620	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

BIRC3_MOUSE
θ value	3.0926 (rank : 314)	NC score	0.100550 (rank : 285)
Query Neighborhood Hits	382	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

CENPE_HUMAN
θ value	3.0926 (rank : 315)	NC score	0.062477 (rank : 361)
Query Neighborhood Hits	382	Target Neighborhood Hits	2060	Shared Neighborhood Hits	175
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

GOGA4_MOUSE
θ value	3.0926 (rank : 316)	NC score	0.073404 (rank : 324)
Query Neighborhood Hits	382	Target Neighborhood Hits	1939	Shared Neighborhood Hits	173
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HIC2_MOUSE
θ value	3.0926 (rank : 317)	NC score	-0.009335 (rank : 514)
Query Neighborhood Hits	382	Target Neighborhood Hits	821	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).

HMMR_MOUSE
θ value	3.0926 (rank : 318)	NC score	0.055115 (rank : 404)
Query Neighborhood Hits	382	Target Neighborhood Hits	1178	Shared Neighborhood Hits	126
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ITSN2_MOUSE
θ value	3.0926 (rank : 319)	NC score	0.034828 (rank : 462)
Query Neighborhood Hits	382	Target Neighborhood Hits	1371	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LNX1_HUMAN
θ value	3.0926 (rank : 320)	NC score	0.253695 (rank : 192)
Query Neighborhood Hits	382	Target Neighborhood Hits	379	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

MYH11_HUMAN
θ value	3.0926 (rank : 321)	NC score	0.051395 (rank : 431)
Query Neighborhood Hits	382	Target Neighborhood Hits	1806	Shared Neighborhood Hits	163
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NEUL1_HUMAN
θ value	3.0926 (rank : 322)	NC score	0.105661 (rank : 277)
Query Neighborhood Hits	382	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	3.0926 (rank : 323)	NC score	0.104448 (rank : 279)
Query Neighborhood Hits	382	Target Neighborhood Hits	106	Shared Neighborhood Hits	67
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RNF4_HUMAN
θ value	3.0926 (rank : 324)	NC score	0.396117 (rank : 146)
Query Neighborhood Hits	382	Target Neighborhood Hits	212	Shared Neighborhood Hits	161
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	3.0926 (rank : 325)	NC score	0.390995 (rank : 147)
Query Neighborhood Hits	382	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

ARI1_HUMAN
θ value	4.03905 (rank : 326)	NC score	0.038635 (rank : 456)
Query Neighborhood Hits	382	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	4.03905 (rank : 327)	NC score	0.038622 (rank : 457)
Query Neighborhood Hits	382	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

BICD2_HUMAN
θ value	4.03905 (rank : 328)	NC score	0.044257 (rank : 448)
Query Neighborhood Hits	382	Target Neighborhood Hits	856	Shared Neighborhood Hits	115
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	4.03905 (rank : 329)	NC score	0.044415 (rank : 447)
Query Neighborhood Hits	382	Target Neighborhood Hits	864	Shared Neighborhood Hits	115
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CALD1_HUMAN
θ value	4.03905 (rank : 330)	NC score	0.046223 (rank : 444)
Query Neighborhood Hits	382	Target Neighborhood Hits	959	Shared Neighborhood Hits	100
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

KIF3C_HUMAN
θ value	4.03905 (rank : 331)	NC score	0.013456 (rank : 497)
Query Neighborhood Hits	382	Target Neighborhood Hits	478	Shared Neighborhood Hits	71
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

KIF5C_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.030193 (rank : 473)
Query Neighborhood Hits	382	Target Neighborhood Hits	974	Shared Neighborhood Hits	111
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

KIF5C_MOUSE
θ value	4.03905 (rank : 333)	NC score	0.030861 (rank : 470)
Query Neighborhood Hits	382	Target Neighborhood Hits	1040	Shared Neighborhood Hits	113
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

MNAB_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.146612 (rank : 244)
Query Neighborhood Hits	382	Target Neighborhood Hits	196	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	4.03905 (rank : 335)	NC score	0.144819 (rank : 247)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	109
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RB6I2_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.057390 (rank : 390)
Query Neighborhood Hits	382	Target Neighborhood Hits	1584	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SNX23_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.031558 (rank : 468)
Query Neighborhood Hits	382	Target Neighborhood Hits	944	Shared Neighborhood Hits	109
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

TAOK2_MOUSE
θ value	4.03905 (rank : 338)	NC score	-0.002719 (rank : 506)
Query Neighborhood Hits	382	Target Neighborhood Hits	1373	Shared Neighborhood Hits	81
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

CF182_MOUSE
θ value	5.27518 (rank : 339)	NC score	0.030828 (rank : 471)
Query Neighborhood Hits	382	Target Neighborhood Hits	551	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CKAP4_MOUSE
θ value	5.27518 (rank : 340)	NC score	0.040954 (rank : 452)
Query Neighborhood Hits	382	Target Neighborhood Hits	596	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CROCC_HUMAN
θ value	5.27518 (rank : 341)	NC score	0.057604 (rank : 388)
Query Neighborhood Hits	382	Target Neighborhood Hits	1409	Shared Neighborhood Hits	141
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DREB_HUMAN
θ value	5.27518 (rank : 342)	NC score	0.026362 (rank : 482)
Query Neighborhood Hits	382	Target Neighborhood Hits	450	Shared Neighborhood Hits	60
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

E2AK4_HUMAN
θ value	5.27518 (rank : 343)	NC score	-0.005165 (rank : 508)
Query Neighborhood Hits	382	Target Neighborhood Hits	1012	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

E2AK4_MOUSE
θ value	5.27518 (rank : 344)	NC score	-0.006248 (rank : 509)
Query Neighborhood Hits	382	Target Neighborhood Hits	984	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

IFT74_MOUSE
θ value	5.27518 (rank : 345)	NC score	0.053675 (rank : 412)
Query Neighborhood Hits	382	Target Neighborhood Hits	939	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

KIF3C_MOUSE
θ value	5.27518 (rank : 346)	NC score	0.014030 (rank : 495)
Query Neighborhood Hits	382	Target Neighborhood Hits	468	Shared Neighborhood Hits	69
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

MAP1A_HUMAN
θ value	5.27518 (rank : 347)	NC score	0.035408 (rank : 461)
Query Neighborhood Hits	382	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NHLC1_HUMAN
θ value	5.27518 (rank : 348)	NC score	0.189982 (rank : 220)
Query Neighborhood Hits	382	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PHF1_MOUSE
θ value	5.27518 (rank : 349)	NC score	0.010975 (rank : 500)
Query Neighborhood Hits	382	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

RN175_HUMAN
θ value	5.27518 (rank : 350)	NC score	0.069990 (rank : 331)
Query Neighborhood Hits	382	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

ROCK1_MOUSE
θ value	5.27518 (rank : 351)	NC score	0.021911 (rank : 488)
Query Neighborhood Hits	382	Target Neighborhood Hits	2126	Shared Neighborhood Hits	146
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TCF8_HUMAN
θ value	5.27518 (rank : 352)	NC score	-0.007554 (rank : 510)
Query Neighborhood Hits	382	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TRAF3_HUMAN
θ value	5.27518 (rank : 353)	NC score	0.183993 (rank : 226)
Query Neighborhood Hits	382	Target Neighborhood Hits	463	Shared Neighborhood Hits	172
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

ARI2_HUMAN
θ value	6.88961 (rank : 354)	NC score	0.064053 (rank : 357)
Query Neighborhood Hits	382	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	6.88961 (rank : 355)	NC score	0.061819 (rank : 363)
Query Neighborhood Hits	382	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

BIRC3_HUMAN
θ value	6.88961 (rank : 356)	NC score	0.117909 (rank : 268)
Query Neighborhood Hits	382	Target Neighborhood Hits	133	Shared Neighborhood Hits	88
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

EEA1_HUMAN
θ value	6.88961 (rank : 357)	NC score	0.058438 (rank : 378)
Query Neighborhood Hits	382	Target Neighborhood Hits	1796	Shared Neighborhood Hits	165
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ITSN1_HUMAN
θ value	6.88961 (rank : 358)	NC score	0.031339 (rank : 469)
Query Neighborhood Hits	382	Target Neighborhood Hits	1757	Shared Neighborhood Hits	120
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	6.88961 (rank : 359)	NC score	0.032158 (rank : 466)
Query Neighborhood Hits	382	Target Neighborhood Hits	1669	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

KMHN1_HUMAN
θ value	6.88961 (rank : 360)	NC score	0.037971 (rank : 459)
Query Neighborhood Hits	382	Target Neighborhood Hits	950	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

LRSM1_HUMAN
θ value	6.88961 (rank : 361)	NC score	0.082267 (rank : 311)
Query Neighborhood Hits	382	Target Neighborhood Hits	1078	Shared Neighborhood Hits	174
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

PEX2_MOUSE
θ value	6.88961 (rank : 362)	NC score	0.085885 (rank : 305)
Query Neighborhood Hits	382	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

RABE2_MOUSE
θ value	6.88961 (rank : 363)	NC score	0.039577 (rank : 454)
Query Neighborhood Hits	382	Target Neighborhood Hits	598	Shared Neighborhood Hits	95
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SPSB2_HUMAN
θ value	6.88961 (rank : 364)	NC score	0.012443 (rank : 498)
Query Neighborhood Hits	382	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q99619	Gene names	SPSB2, GRCC9, SSB2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SYCP1_HUMAN
θ value	6.88961 (rank : 365)	NC score	0.054935 (rank : 406)
Query Neighborhood Hits	382	Target Neighborhood Hits	1313	Shared Neighborhood Hits	131
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TPM3_MOUSE
θ value	6.88961 (rank : 366)	NC score	0.041179 (rank : 450)
Query Neighborhood Hits	382	Target Neighborhood Hits	676	Shared Neighborhood Hits	92
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

BIRC2_HUMAN
θ value	8.99809 (rank : 367)	NC score	0.113446 (rank : 270)
Query Neighborhood Hits	382	Target Neighborhood Hits	142	Shared Neighborhood Hits	94
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

CCD70_HUMAN
θ value	8.99809 (rank : 368)	NC score	0.014037 (rank : 494)
Query Neighborhood Hits	382	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NSX1, Q8N7A8, Q9H097	Gene names	CCDC70
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 70 precursor.

CD016_HUMAN
θ value	8.99809 (rank : 369)	NC score	0.014756 (rank : 493)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

CING_MOUSE
θ value	8.99809 (rank : 370)	NC score	0.055688 (rank : 399)
Query Neighborhood Hits	382	Target Neighborhood Hits	1432	Shared Neighborhood Hits	137
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CKAP4_HUMAN
θ value	8.99809 (rank : 371)	NC score	0.037730 (rank : 460)
Query Neighborhood Hits	382	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

GRAP1_MOUSE
θ value	8.99809 (rank : 372)	NC score	0.051746 (rank : 429)
Query Neighborhood Hits	382	Target Neighborhood Hits	1234	Shared Neighborhood Hits	139
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

ITSN2_HUMAN
θ value	8.99809 (rank : 373)	NC score	0.025674 (rank : 484)
Query Neighborhood Hits	382	Target Neighborhood Hits	1173	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LZTS1_MOUSE
θ value	8.99809 (rank : 374)	NC score	0.031946 (rank : 467)
Query Neighborhood Hits	382	Target Neighborhood Hits	540	Shared Neighborhood Hits	87
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MINK1_HUMAN
θ value	8.99809 (rank : 375)	NC score	0.001636 (rank : 502)
Query Neighborhood Hits	382	Target Neighborhood Hits	1477	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH14_MOUSE
θ value	8.99809 (rank : 376)	NC score	0.041940 (rank : 449)
Query Neighborhood Hits	382	Target Neighborhood Hits	1225	Shared Neighborhood Hits	130
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH9_MOUSE
θ value	8.99809 (rank : 377)	NC score	0.045585 (rank : 445)
Query Neighborhood Hits	382	Target Neighborhood Hits	1829	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NAF1_MOUSE
θ value	8.99809 (rank : 378)	NC score	0.048470 (rank : 442)
Query Neighborhood Hits	382	Target Neighborhood Hits	852	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PDCD7_MOUSE
θ value	8.99809 (rank : 379)	NC score	0.027520 (rank : 477)
Query Neighborhood Hits	382	Target Neighborhood Hits	214	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

RB6I2_MOUSE
θ value	8.99809 (rank : 380)	NC score	0.056291 (rank : 394)
Query Neighborhood Hits	382	Target Neighborhood Hits	1433	Shared Neighborhood Hits	141
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RN152_HUMAN
θ value	8.99809 (rank : 381)	NC score	0.188109 (rank : 223)
Query Neighborhood Hits	382	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	8.99809 (rank : 382)	NC score	0.192120 (rank : 218)
Query Neighborhood Hits	382	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

AKAP9_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.058635 (rank : 376)
Query Neighborhood Hits	382	Target Neighborhood Hits	1710	Shared Neighborhood Hits	140
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR26_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.055752 (rank : 398)
Query Neighborhood Hits	382	Target Neighborhood Hits	1614	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AZI1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.059149 (rank : 371)
Query Neighborhood Hits	382	Target Neighborhood Hits	1000	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.061187 (rank : 366)
Query Neighborhood Hits	382	Target Neighborhood Hits	990	Shared Neighborhood Hits	119
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BIRC2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.107738 (rank : 275)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC4_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.066237 (rank : 345)
Query Neighborhood Hits	382	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.065521 (rank : 352)
Query Neighborhood Hits	382	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BPAEA_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.050737 (rank : 435)
Query Neighborhood Hits	382	Target Neighborhood Hits	1480	Shared Neighborhood Hits	144
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BT3A2_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.185550 (rank : 225)
Query Neighborhood Hits	382	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.177071 (rank : 227)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.171061 (rank : 229)
Query Neighborhood Hits	382	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CASP_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.050926 (rank : 434)
Query Neighborhood Hits	382	Target Neighborhood Hits	1152	Shared Neighborhood Hits	127
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD11_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.055381 (rank : 402)
Query Neighborhood Hits	382	Target Neighborhood Hits	822	Shared Neighborhood Hits	106
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD27_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.052951 (rank : 421)
Query Neighborhood Hits	382	Target Neighborhood Hits	594	Shared Neighborhood Hits	85
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD46_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.067489 (rank : 339)
Query Neighborhood Hits	382	Target Neighborhood Hits	1430	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CD276_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.085665 (rank : 306)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.095538 (rank : 291)
Query Neighborhood Hits	382	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD86_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.072755 (rank : 326)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CD86_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.068164 (rank : 335)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CE290_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.062824 (rank : 360)
Query Neighborhood Hits	382	Target Neighborhood Hits	1553	Shared Neighborhood Hits	162
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP55_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.053030 (rank : 418)
Query Neighborhood Hits	382	Target Neighborhood Hits	693	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP63_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.053619 (rank : 413)
Query Neighborhood Hits	382	Target Neighborhood Hits	1005	Shared Neighborhood Hits	126
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CM007_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.237511 (rank : 200)
Query Neighborhood Hits	382	Target Neighborhood Hits	422	Shared Neighborhood Hits	167
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.266286 (rank : 184)
Query Neighborhood Hits	382	Target Neighborhood Hits	416	Shared Neighborhood Hits	168
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CN145_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.052404 (rank : 424)
Query Neighborhood Hits	382	Target Neighborhood Hits	1196	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.054692 (rank : 408)
Query Neighborhood Hits	382	Target Neighborhood Hits	916	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNOT4_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.097294 (rank : 290)
Query Neighborhood Hits	382	Target Neighborhood Hits	207	Shared Neighborhood Hits	43
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.092786 (rank : 297)
Query Neighborhood Hits	382	Target Neighborhood Hits	277	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNTRB_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.052060 (rank : 426)
Query Neighborhood Hits	382	Target Neighborhood Hits	1029	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CT096_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.053097 (rank : 417)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.056048 (rank : 396)
Query Neighborhood Hits	382	Target Neighborhood Hits	1059	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.050651 (rank : 436)
Query Neighborhood Hits	382	Target Neighborhood Hits	902	Shared Neighborhood Hits	113
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DZIP3_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.084643 (rank : 309)
Query Neighborhood Hits	382	Target Neighborhood Hits	399	Shared Neighborhood Hits	125
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.088854 (rank : 301)
Query Neighborhood Hits	382	Target Neighborhood Hits	414	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

EEA1_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.052391 (rank : 425)
Query Neighborhood Hits	382	Target Neighborhood Hits	1637	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FLIP1_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.058243 (rank : 380)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	145
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.058845 (rank : 374)
Query Neighborhood Hits	382	Target Neighborhood Hits	1176	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FSD1L_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.093661 (rank : 295)
Query Neighborhood Hits	382	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.105442 (rank : 278)
Query Neighborhood Hits	382	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCC1_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.059862 (rank : 369)
Query Neighborhood Hits	382	Target Neighborhood Hits	777	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC2_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.057833 (rank : 386)
Query Neighborhood Hits	382	Target Neighborhood Hits	1558	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.065720 (rank : 350)
Query Neighborhood Hits	382	Target Neighborhood Hits	1619	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA1_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.051180 (rank : 433)
Query Neighborhood Hits	382	Target Neighborhood Hits	1222	Shared Neighborhood Hits	130
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA3_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.054200 (rank : 411)
Query Neighborhood Hits	382	Target Neighborhood Hits	1437	Shared Neighborhood Hits	144
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA6_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.055290 (rank : 403)
Query Neighborhood Hits	382	Target Neighborhood Hits	1007	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GOLI_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.081633 (rank : 313)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	71
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.082050 (rank : 312)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

HHLA2_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.072272 (rank : 327)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMMR_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.054381 (rank : 409)
Query Neighborhood Hits	382	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ICOSL_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.084883 (rank : 308)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.067000 (rank : 341)
Query Neighborhood Hits	382	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

INCE_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.061455 (rank : 365)
Query Neighborhood Hits	382	Target Neighborhood Hits	978	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

KTN1_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.052988 (rank : 419)
Query Neighborhood Hits	382	Target Neighborhood Hits	1324	Shared Neighborhood Hits	148
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MAT1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.131241 (rank : 257)
Query Neighborhood Hits	382	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.127937 (rank : 260)
Query Neighborhood Hits	382	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MGRN1_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.121673 (rank : 264)
Query Neighborhood Hits	382	Target Neighborhood Hits	192	Shared Neighborhood Hits	104
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.122974 (rank : 262)
Query Neighborhood Hits	382	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MIB2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.071602 (rank : 328)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	100
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.063788 (rank : 358)
Query Neighborhood Hits	382	Target Neighborhood Hits	409	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MKRN1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.067345 (rank : 340)
Query Neighborhood Hits	382	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

MKRN1_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.065794 (rank : 348)
Query Neighborhood Hits	382	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

MKRN2_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.085204 (rank : 307)
Query Neighborhood Hits	382	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.087569 (rank : 302)
Query Neighborhood Hits	382	Target Neighborhood Hits	130	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN3_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.080714 (rank : 316)
Query Neighborhood Hits	382	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

MKRN4_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.088887 (rank : 300)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MOG_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.165524 (rank : 231)
Query Neighborhood Hits	382	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.164983 (rank : 232)
Query Neighborhood Hits	382	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

NHLC1_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.193860 (rank : 217)
Query Neighborhood Hits	382	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NIN_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.061544 (rank : 364)
Query Neighborhood Hits	382	Target Neighborhood Hits	1376	Shared Neighborhood Hits	142
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUMA1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.064125 (rank : 355)
Query Neighborhood Hits	382	Target Neighborhood Hits	1523	Shared Neighborhood Hits	149
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PCNT_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.053256 (rank : 416)
Query Neighborhood Hits	382	Target Neighborhood Hits	1207	Shared Neighborhood Hits	141
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDL1_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.058855 (rank : 373)
Query Neighborhood Hits	382	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.077057 (rank : 318)
Query Neighborhood Hits	382	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.066529 (rank : 344)
Query Neighborhood Hits	382	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.062857 (rank : 359)
Query Neighborhood Hits	382	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PEX2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.055861 (rank : 397)
Query Neighborhood Hits	382	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

RABE1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.056187 (rank : 395)
Query Neighborhood Hits	382	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.057975 (rank : 385)
Query Neighborhood Hits	382	Target Neighborhood Hits	1105	Shared Neighborhood Hits	128
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RBCC1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.052968 (rank : 420)
Query Neighborhood Hits	382	Target Neighborhood Hits	1048	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBP24_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.058084 (rank : 383)
Query Neighborhood Hits	382	Target Neighborhood Hits	1559	Shared Neighborhood Hits	156
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RC3H1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.187644 (rank : 224)
Query Neighborhood Hits	382	Target Neighborhood Hits	433	Shared Neighborhood Hits	131
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.195160 (rank : 216)
Query Neighborhood Hits	382	Target Neighborhood Hits	244	Shared Neighborhood Hits	128
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

REST_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.055551 (rank : 400)
Query Neighborhood Hits	382	Target Neighborhood Hits	1605	Shared Neighborhood Hits	153
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RN103_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.102151 (rank : 283)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.101741 (rank : 284)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

RN122_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.116715 (rank : 269)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.109916 (rank : 274)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN126_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.095107 (rank : 292)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.104176 (rank : 281)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN133_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.068149 (rank : 336)
Query Neighborhood Hits	382	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

RN146_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.312421 (rank : 164)
Query Neighborhood Hits	382	Target Neighborhood Hits	162	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.310153 (rank : 168)
Query Neighborhood Hits	382	Target Neighborhood Hits	161	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN165_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.111996 (rank : 272)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN183_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.374161 (rank : 148)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.323494 (rank : 161)
Query Neighborhood Hits	382	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF11_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.065986 (rank : 346)
Query Neighborhood Hits	382	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

RNF11_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.065733 (rank : 349)
Query Neighborhood Hits	382	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

RNF12_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.077261 (rank : 317)
Query Neighborhood Hits	382	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

RNF12_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.083844 (rank : 310)
Query Neighborhood Hits	382	Target Neighborhood Hits	159	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

RNF17_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.051495 (rank : 430)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	39
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

RNF24_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.097872 (rank : 289)
Query Neighborhood Hits	382	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

RNF24_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.098628 (rank : 288)
Query Neighborhood Hits	382	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF26_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.106589 (rank : 276)
Query Neighborhood Hits	382	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF37_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.055004 (rank : 405)
Query Neighborhood Hits	382	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

RNF6_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.068783 (rank : 334)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.052008 (rank : 427)
Query Neighborhood Hits	382	Target Neighborhood Hits	1208	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SDCG8_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.058492 (rank : 377)
Query Neighborhood Hits	382	Target Neighborhood Hits	886	Shared Neighborhood Hits	114
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SIA1A_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.057639 (rank : 387)
Query Neighborhood Hits	382	Target Neighborhood Hits	72	Shared Neighborhood Hits	55
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

SIA1B_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.059034 (rank : 372)
Query Neighborhood Hits	382	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

SIAH1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.058261 (rank : 379)
Query Neighborhood Hits	382	Target Neighborhood Hits	72	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

SIAH2_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.076338 (rank : 321)
Query Neighborhood Hits	382	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.075462 (rank : 322)
Query Neighborhood Hits	382	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SMC2_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.054361 (rank : 410)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	135
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

T3JAM_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.050013 (rank : 441)
Query Neighborhood Hits	382	Target Neighborhood Hits	533	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TPR_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.060170 (rank : 368)
Query Neighborhood Hits	382	Target Neighborhood Hits	1921	Shared Neighborhood Hits	156
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAF2_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.191915 (rank : 219)
Query Neighborhood Hits	382	Target Neighborhood Hits	402	Shared Neighborhood Hits	135
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.189682 (rank : 222)
Query Neighborhood Hits	382	Target Neighborhood Hits	394	Shared Neighborhood Hits	132
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.189935 (rank : 221)
Query Neighborhood Hits	382	Target Neighborhood Hits	476	Shared Neighborhood Hits	184
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRI14_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.721380 (rank : 64)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	114
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI42_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.329574 (rank : 159)
Query Neighborhood Hits	382	Target Neighborhood Hits	283	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI45_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.268975 (rank : 183)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.256446 (rank : 189)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI66_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.098639 (rank : 287)
Query Neighborhood Hits	382	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.102957 (rank : 282)
Query Neighborhood Hits	382	Target Neighborhood Hits	491	Shared Neighborhood Hits	83
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRIPB_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.054904 (rank : 407)
Query Neighborhood Hits	382	Target Neighborhood Hits	1587	Shared Neighborhood Hits	148
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UB7I3_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.113396 (rank : 271)
Query Neighborhood Hits	382	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.135422 (rank : 252)
Query Neighborhood Hits	382	Target Neighborhood Hits	131	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

ZN363_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.050547 (rank : 437)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN364_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.111267 (rank : 273)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

ZN364_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.104426 (rank : 280)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.099477 (rank : 286)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.081311 (rank : 314)
Query Neighborhood Hits	382	Target Neighborhood Hits	132	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRI35_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	382	Target Neighborhood Hits	382	Shared Neighborhood Hits	382
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
NC score	0.977287 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	382	Target Neighborhood Hits	465	Shared Neighborhood Hits	303
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI60_HUMAN
NC score	0.941286 (rank : 3)	θ value	1.56636e-44 (rank : 7)
Query Neighborhood Hits	382	Target Neighborhood Hits	357	Shared Neighborhood Hits	257
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI11_MOUSE
NC score	0.939565 (rank : 4)	θ value	5.20228e-48 (rank : 4)
Query Neighborhood Hits	382	Target Neighborhood Hits	329	Shared Neighborhood Hits	239
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.939505 (rank : 5)	θ value	1.91031e-50 (rank : 3)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	234
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRIM4_HUMAN
NC score	0.935208 (rank : 6)	θ value	1.16434e-31 (rank : 28)
Query Neighborhood Hits	382	Target Neighborhood Hits	321	Shared Neighborhood Hits	236
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI17_HUMAN
NC score	0.932665 (rank : 7)	θ value	5.39604e-37 (rank : 21)
Query Neighborhood Hits	382	Target Neighborhood Hits	318	Shared Neighborhood Hits	242
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI10_HUMAN
NC score	0.929209 (rank : 8)	θ value	1.9192e-34 (rank : 23)
Query Neighborhood Hits	382	Target Neighborhood Hits	315	Shared Neighborhood Hits	241
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RO52_MOUSE
NC score	0.928732 (rank : 9)	θ value	2.58786e-39 (rank : 17)
Query Neighborhood Hits	382	Target Neighborhood Hits	360	Shared Neighborhood Hits	252
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRIM7_MOUSE
NC score	0.928476 (rank : 10)	θ value	6.58091e-43 (rank : 14)
Query Neighborhood Hits	382	Target Neighborhood Hits	358	Shared Neighborhood Hits	236
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM7_HUMAN
NC score	0.928200 (rank : 11)	θ value	8.04462e-41 (rank : 15)
Query Neighborhood Hits	382	Target Neighborhood Hits	336	Shared Neighborhood Hits	233
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

RO52_HUMAN
NC score	0.927984 (rank : 12)	θ value	4.86918e-46 (rank : 5)
Query Neighborhood Hits	382	Target Neighborhood Hits	419	Shared Neighborhood Hits	272
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_MOUSE
NC score	0.927578 (rank : 13)	θ value	5.76516e-39 (rank : 18)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	201
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI10_MOUSE
NC score	0.927487 (rank : 14)	θ value	2.12192e-33 (rank : 24)
Query Neighborhood Hits	382	Target Neighborhood Hits	285	Shared Neighborhood Hits	235
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI68_MOUSE
NC score	0.926460 (rank : 15)	θ value	1.32601e-43 (rank : 12)
Query Neighborhood Hits	382	Target Neighborhood Hits	356	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI68_HUMAN
NC score	0.925925 (rank : 16)	θ value	1.79215e-40 (rank : 16)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	220
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI27_HUMAN
NC score	0.924828 (rank : 17)	θ value	3.48949e-44 (rank : 8)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	224
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI39_MOUSE
NC score	0.923778 (rank : 18)	θ value	2.41655e-45 (rank : 6)
Query Neighborhood Hits	382	Target Neighborhood Hits	691	Shared Neighborhood Hits	300
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI43_HUMAN
NC score	0.923708 (rank : 19)	θ value	6.38894e-30 (rank : 30)
Query Neighborhood Hits	382	Target Neighborhood Hits	341	Shared Neighborhood Hits	239
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI39_HUMAN
NC score	0.922500 (rank : 20)	θ value	1.73182e-43 (rank : 13)
Query Neighborhood Hits	382	Target Neighborhood Hits	693	Shared Neighborhood Hits	304
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI27_MOUSE
NC score	0.922185 (rank : 21)	θ value	1.01529e-43 (rank : 11)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	214
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI26_HUMAN
NC score	0.919470 (rank : 22)	θ value	9.2256e-29 (rank : 35)
Query Neighborhood Hits	382	Target Neighborhood Hits	335	Shared Neighborhood Hits	246
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI38_HUMAN
NC score	0.917257 (rank : 23)	θ value	2.12192e-33 (rank : 25)
Query Neighborhood Hits	382	Target Neighborhood Hits	373	Shared Neighborhood Hits	235
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI50_MOUSE
NC score	0.915918 (rank : 24)	θ value	1.57e-36 (rank : 22)
Query Neighborhood Hits	382	Target Neighborhood Hits	326	Shared Neighborhood Hits	243
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_MOUSE
NC score	0.915682 (rank : 25)	θ value	5.40856e-29 (rank : 34)
Query Neighborhood Hits	382	Target Neighborhood Hits	339	Shared Neighborhood Hits	246
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI50_HUMAN
NC score	0.914451 (rank : 26)	θ value	9.83387e-39 (rank : 19)
Query Neighborhood Hits	382	Target Neighborhood Hits	294	Shared Neighborhood Hits	233
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI62_MOUSE
NC score	0.913971 (rank : 27)	θ value	7.77379e-44 (rank : 10)
Query Neighborhood Hits	382	Target Neighborhood Hits	478	Shared Neighborhood Hits	253
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM6_HUMAN
NC score	0.910975 (rank : 28)	θ value	6.17384e-33 (rank : 26)
Query Neighborhood Hits	382	Target Neighborhood Hits	412	Shared Neighborhood Hits	248
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI17_MOUSE
NC score	0.910822 (rank : 29)	θ value	8.32485e-38 (rank : 20)
Query Neighborhood Hits	382	Target Neighborhood Hits	620	Shared Neighborhood Hits	269
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRIM6_MOUSE
NC score	0.909654 (rank : 30)	θ value	2.86786e-30 (rank : 29)
Query Neighborhood Hits	382	Target Neighborhood Hits	451	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM5_HUMAN
NC score	0.907990 (rank : 31)	θ value	1.47289e-26 (rank : 36)
Query Neighborhood Hits	382	Target Neighborhood Hits	424	Shared Neighborhood Hits	254
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI41_HUMAN
NC score	0.906625 (rank : 32)	θ value	3.06405e-32 (rank : 27)
Query Neighborhood Hits	382	Target Neighborhood Hits	349	Shared Neighborhood Hits	220
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI22_HUMAN
NC score	0.905457 (rank : 33)	θ value	4.14116e-29 (rank : 32)
Query Neighborhood Hits	382	Target Neighborhood Hits	396	Shared Neighborhood Hits	252
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI62_HUMAN
NC score	0.905198 (rank : 34)	θ value	7.77379e-44 (rank : 9)
Query Neighborhood Hits	382	Target Neighborhood Hits	584	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI15_HUMAN
NC score	0.902954 (rank : 35)	θ value	5.40856e-29 (rank : 33)
Query Neighborhood Hits	382	Target Neighborhood Hits	395	Shared Neighborhood Hits	235
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI30_MOUSE
NC score	0.900519 (rank : 36)	θ value	1.05554e-24 (rank : 38)
Query Neighborhood Hits	382	Target Neighborhood Hits	434	Shared Neighborhood Hits	252
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI34_HUMAN
NC score	0.889787 (rank : 37)	θ value	6.18819e-25 (rank : 37)
Query Neighborhood Hits	382	Target Neighborhood Hits	416	Shared Neighborhood Hits	223
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
NC score	0.887700 (rank : 38)	θ value	2.42779e-29 (rank : 31)
Query Neighborhood Hits	382	Target Neighborhood Hits	332	Shared Neighborhood Hits	208
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI49_HUMAN
NC score	0.886658 (rank : 39)	θ value	3.51386e-20 (rank : 40)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	178
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI31_HUMAN
NC score	0.875306 (rank : 40)	θ value	3.88503e-19 (rank : 41)
Query Neighborhood Hits	382	Target Neighborhood Hits	299	Shared Neighborhood Hits	225
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI48_HUMAN
NC score	0.864778 (rank : 41)	θ value	5.8054e-15 (rank : 49)
Query Neighborhood Hits	382	Target Neighborhood Hits	192	Shared Neighborhood Hits	177
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI12_MOUSE
NC score	0.858344 (rank : 42)	θ value	5.60996e-18 (rank : 45)
Query Neighborhood Hits	382	Target Neighborhood Hits	387	Shared Neighborhood Hits	224
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

MEFV_HUMAN
NC score	0.840716 (rank : 43)	θ value	1.80048e-24 (rank : 39)
Query Neighborhood Hits	382	Target Neighborhood Hits	431	Shared Neighborhood Hits	144
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

RNF39_HUMAN
NC score	0.839534 (rank : 44)	θ value	1.133e-10 (rank : 68)
Query Neighborhood Hits	382	Target Neighborhood Hits	200	Shared Neighborhood Hits	181
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI52_HUMAN
NC score	0.839385 (rank : 45)	θ value	5.62301e-10 (rank : 71)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	191
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI73_HUMAN
NC score	0.836481 (rank : 46)	θ value	4.29542e-18 (rank : 44)
Query Neighborhood Hits	382	Target Neighborhood Hits	258	Shared Neighborhood Hits	213
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
NC score	0.833503 (rank : 47)	θ value	9.56915e-18 (rank : 46)
Query Neighborhood Hits	382	Target Neighborhood Hits	249	Shared Neighborhood Hits	207
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI65_HUMAN
NC score	0.828909 (rank : 48)	θ value	1.33837e-11 (rank : 65)
Query Neighborhood Hits	382	Target Neighborhood Hits	330	Shared Neighborhood Hits	241
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
NC score	0.816272 (rank : 49)	θ value	2.20605e-14 (rank : 53)
Query Neighborhood Hits	382	Target Neighborhood Hits	340	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI40_HUMAN
NC score	0.803551 (rank : 50)	θ value	2.79066e-09 (rank : 76)
Query Neighborhood Hits	382	Target Neighborhood Hits	279	Shared Neighborhood Hits	194
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

RFPL3_HUMAN
NC score	0.794426 (rank : 51)	θ value	3.52202e-12 (rank : 62)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	119
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL2_HUMAN
NC score	0.788750 (rank : 52)	θ value	1.29331e-14 (rank : 50)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	110
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL1_HUMAN
NC score	0.786110 (rank : 53)	θ value	2.69671e-12 (rank : 61)
Query Neighborhood Hits	382	Target Neighborhood Hits	119	Shared Neighborhood Hits	107
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI13_MOUSE
NC score	0.785109 (rank : 54)	θ value	3.52202e-12 (rank : 64)
Query Neighborhood Hits	382	Target Neighborhood Hits	282	Shared Neighborhood Hits	214
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.782355 (rank : 55)	θ value	3.52202e-12 (rank : 63)
Query Neighborhood Hits	382	Target Neighborhood Hits	274	Shared Neighborhood Hits	211
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

ERMAP_HUMAN
NC score	0.771544 (rank : 56)	θ value	2.20605e-14 (rank : 52)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	79
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI59_MOUSE
NC score	0.754932 (rank : 57)	θ value	2.0648e-12 (rank : 60)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	211
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.754664 (rank : 58)	θ value	3.18553e-13 (rank : 57)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	215
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI25_MOUSE
NC score	0.746182 (rank : 59)	θ value	2.98157e-11 (rank : 66)
Query Neighborhood Hits	382	Target Neighborhood Hits	446	Shared Neighborhood Hits	258
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI25_HUMAN
NC score	0.741945 (rank : 60)	θ value	9.26847e-13 (rank : 59)
Query Neighborhood Hits	382	Target Neighborhood Hits	472	Shared Neighborhood Hits	265
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI14_MOUSE
NC score	0.736641 (rank : 61)	θ value	0.00102713 (rank : 141)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

ERMAP_MOUSE
NC score	0.734811 (rank : 62)	θ value	9.26847e-13 (rank : 58)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

BSPRY_MOUSE
NC score	0.725564 (rank : 63)	θ value	2.20605e-14 (rank : 51)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	100
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI14_HUMAN
NC score	0.721380 (rank : 64)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	114
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

BTNL9_HUMAN
NC score	0.717550 (rank : 65)	θ value	2.13179e-17 (rank : 47)
Query Neighborhood Hits	382	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

BT2A2_HUMAN
NC score	0.715561 (rank : 66)	θ value	1.16975e-15 (rank : 48)
Query Neighborhood Hits	382	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BSPRY_HUMAN
NC score	0.714659 (rank : 67)	θ value	5.62301e-10 (rank : 70)
Query Neighborhood Hits	382	Target Neighborhood Hits	115	Shared Neighborhood Hits	98
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT3A3_HUMAN
NC score	0.709792 (rank : 68)	θ value	6.62687e-19 (rank : 42)
Query Neighborhood Hits	382	Target Neighborhood Hits	233	Shared Neighborhood Hits	80
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT1A1_MOUSE
NC score	0.707043 (rank : 69)	θ value	3.76295e-14 (rank : 54)
Query Neighborhood Hits	382	Target Neighborhood Hits	252	Shared Neighborhood Hits	80
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A1_HUMAN
NC score	0.704804 (rank : 70)	θ value	6.41864e-14 (rank : 55)
Query Neighborhood Hits	382	Target Neighborhood Hits	229	Shared Neighborhood Hits	82
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT2A1_HUMAN
NC score	0.702233 (rank : 71)	θ value	2.43908e-13 (rank : 56)
Query Neighborhood Hits	382	Target Neighborhood Hits	185	Shared Neighborhood Hits	79
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

TRIM8_HUMAN
NC score	0.701472 (rank : 72)	θ value	2.98157e-11 (rank : 67)
Query Neighborhood Hits	382	Target Neighborhood Hits	650	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
NC score	0.700976 (rank : 73)	θ value	1.47974e-10 (rank : 69)
Query Neighborhood Hits	382	Target Neighborhood Hits	674	Shared Neighborhood Hits	256
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BT1A1_HUMAN
NC score	0.700814 (rank : 74)	θ value	3.28887e-18 (rank : 43)
Query Neighborhood Hits	382	Target Neighborhood Hits	322	Shared Neighborhood Hits	80
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BTNL3_HUMAN
NC score	0.698711 (rank : 75)	θ value	1.63604e-09 (rank : 75)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BT2A3_HUMAN
NC score	0.697828 (rank : 76)	θ value	7.34386e-10 (rank : 72)
Query Neighborhood Hits	382	Target Neighborhood Hits	195	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL8_HUMAN
NC score	0.681232 (rank : 77)	θ value	7.34386e-10 (rank : 73)
Query Neighborhood Hits	382	Target Neighborhood Hits	177	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

MEFV_MOUSE
NC score	0.666720 (rank : 78)	θ value	1.80886e-08 (rank : 82)
Query Neighborhood Hits	382	Target Neighborhood Hits	236	Shared Neighborhood Hits	108
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI47_MOUSE
NC score	0.658716 (rank : 79)	θ value	2.61198e-07 (rank : 89)
Query Neighborhood Hits	382	Target Neighborhood Hits	295	Shared Neighborhood Hits	208
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI18_HUMAN
NC score	0.648018 (rank : 80)	θ value	1.38499e-08 (rank : 80)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	213
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI47_HUMAN
NC score	0.646741 (rank : 81)	θ value	3.41135e-07 (rank : 90)
Query Neighborhood Hits	382	Target Neighborhood Hits	286	Shared Neighborhood Hits	209
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI16_HUMAN
NC score	0.641953 (rank : 82)	θ value	4.92598e-06 (rank : 99)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	130
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI63_MOUSE
NC score	0.637183 (rank : 83)	θ value	4.45536e-07 (rank : 91)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	165
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI16_MOUSE
NC score	0.635021 (rank : 84)	θ value	0.0330416 (rank : 183)
Query Neighborhood Hits	382	Target Neighborhood Hits	196	Shared Neighborhood Hits	116
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI63_HUMAN
NC score	0.634646 (rank : 85)	θ value	8.11959e-09 (rank : 78)
Query Neighborhood Hits	382	Target Neighborhood Hits	298	Shared Neighborhood Hits	177
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI18_MOUSE
NC score	0.634347 (rank : 86)	θ value	5.26297e-08 (rank : 84)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	215
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI32_HUMAN
NC score	0.629365 (rank : 87)	θ value	1.69304e-06 (rank : 95)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.625717 (rank : 88)	θ value	2.61198e-07 (rank : 88)
Query Neighborhood Hits	382	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

ZN179_HUMAN
NC score	0.623932 (rank : 89)	θ value	0.00869519 (rank : 162)
Query Neighborhood Hits	382	Target Neighborhood Hits	178	Shared Neighborhood Hits	143
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI55_HUMAN
NC score	0.617988 (rank : 90)	θ value	0.00020696 (rank : 117)
Query Neighborhood Hits	382	Target Neighborhood Hits	292	Shared Neighborhood Hits	171
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM1_HUMAN
NC score	0.616434 (rank : 91)	θ value	5.81887e-07 (rank : 93)
Query Neighborhood Hits	382	Target Neighborhood Hits	345	Shared Neighborhood Hits	225
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

SPRY4_MOUSE
NC score	0.616224 (rank : 92)	θ value	0.00869519 (rank : 161)
Query Neighborhood Hits	382	Target Neighborhood Hits	82	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRIM1_MOUSE
NC score	0.615239 (rank : 93)	θ value	1.38499e-08 (rank : 81)
Query Neighborhood Hits	382	Target Neighborhood Hits	361	Shared Neighborhood Hits	226
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM3_MOUSE
NC score	0.613937 (rank : 94)	θ value	7.34386e-10 (rank : 74)
Query Neighborhood Hits	382	Target Neighborhood Hits	351	Shared Neighborhood Hits	210
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.610894 (rank : 95)	θ value	6.21693e-09 (rank : 77)
Query Neighborhood Hits	382	Target Neighborhood Hits	357	Shared Neighborhood Hits	214
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRI54_HUMAN
NC score	0.607067 (rank : 96)	θ value	5.81887e-07 (rank : 92)
Query Neighborhood Hits	382	Target Neighborhood Hits	209	Shared Neighborhood Hits	163
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM2_HUMAN
NC score	0.606204 (rank : 97)	θ value	8.11959e-09 (rank : 79)
Query Neighborhood Hits	382	Target Neighborhood Hits	330	Shared Neighborhood Hits	217
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI54_MOUSE
NC score	0.604181 (rank : 98)	θ value	7.59969e-07 (rank : 94)
Query Neighborhood Hits	382	Target Neighborhood Hits	197	Shared Neighborhood Hits	158
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM2_MOUSE
NC score	0.604126 (rank : 99)	θ value	3.08544e-08 (rank : 83)
Query Neighborhood Hits	382	Target Neighborhood Hits	331	Shared Neighborhood Hits	215
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

SPRY4_HUMAN
NC score	0.596745 (rank : 100)	θ value	0.0961366 (rank : 206)
Query Neighborhood Hits	382	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI37_MOUSE
NC score	0.583292 (rank : 101)	θ value	1.99992e-07 (rank : 87)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	181
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.583271 (rank : 102)	θ value	1.99992e-07 (rank : 86)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	178
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

BFAR_HUMAN
NC score	0.583090 (rank : 103)	θ value	2.88788e-06 (rank : 96)
Query Neighborhood Hits	382	Target Neighborhood Hits	222	Shared Neighborhood Hits	168
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI44_MOUSE
NC score	0.580669 (rank : 104)	θ value	0.000602161 (rank : 132)
Query Neighborhood Hits	382	Target Neighborhood Hits	327	Shared Neighborhood Hits	108
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

BFAR_MOUSE
NC score	0.576192 (rank : 105)	θ value	1.99992e-07 (rank : 85)
Query Neighborhood Hits	382	Target Neighborhood Hits	232	Shared Neighborhood Hits	170
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI44_HUMAN
NC score	0.571899 (rank : 106)	θ value	0.00020696 (rank : 116)
Query Neighborhood Hits	382	Target Neighborhood Hits	393	Shared Neighborhood Hits	118
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

ZN313_MOUSE
NC score	0.552881 (rank : 107)	θ value	0.000786445 (rank : 138)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	194
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PEX10_HUMAN
NC score	0.550316 (rank : 108)	θ value	0.0431538 (rank : 187)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	196
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

BRCA1_HUMAN
NC score	0.541728 (rank : 109)	θ value	5.44631e-05 (rank : 104)
Query Neighborhood Hits	382	Target Neighborhood Hits	381	Shared Neighborhood Hits	199
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

ZN313_HUMAN
NC score	0.539372 (rank : 110)	θ value	0.00175202 (rank : 146)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	190
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RN125_MOUSE
NC score	0.537672 (rank : 111)	θ value	0.00035302 (rank : 121)
Query Neighborhood Hits	382	Target Neighborhood Hits	220	Shared Neighborhood Hits	166
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
NC score	0.537186 (rank : 112)	θ value	0.00035302 (rank : 122)
Query Neighborhood Hits	382	Target Neighborhood Hits	240	Shared Neighborhood Hits	174
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.532450 (rank : 113)	θ value	0.00035302 (rank : 123)
Query Neighborhood Hits	382	Target Neighborhood Hits	248	Shared Neighborhood Hits	180
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

BRCA1_MOUSE
NC score	0.530287 (rank : 114)	θ value	5.44631e-05 (rank : 105)
Query Neighborhood Hits	382	Target Neighborhood Hits	436	Shared Neighborhood Hits	193
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN125_HUMAN
NC score	0.528580 (rank : 115)	θ value	0.00509761 (rank : 155)
Query Neighborhood Hits	382	Target Neighborhood Hits	230	Shared Neighborhood Hits	175
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN168_HUMAN
NC score	0.524244 (rank : 116)	θ value	0.0330416 (rank : 179)
Query Neighborhood Hits	382	Target Neighborhood Hits	370	Shared Neighborhood Hits	201
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RNF8_MOUSE
NC score	0.519628 (rank : 117)	θ value	1.87187e-05 (rank : 102)
Query Neighborhood Hits	382	Target Neighborhood Hits	618	Shared Neighborhood Hits	267
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RNF8_HUMAN
NC score	0.499234 (rank : 118)	θ value	1.87187e-05 (rank : 101)
Query Neighborhood Hits	382	Target Neighborhood Hits	622	Shared Neighborhood Hits	261
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

TRI29_MOUSE
NC score	0.496742 (rank : 119)	θ value	0.279714 (rank : 233)
Query Neighborhood Hits	382	Target Neighborhood Hits	306	Shared Neighborhood Hits	127
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

RN168_MOUSE
NC score	0.496520 (rank : 120)	θ value	0.0961366 (rank : 203)
Query Neighborhood Hits	382	Target Neighborhood Hits	440	Shared Neighborhood Hits	218
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI29_HUMAN
NC score	0.486558 (rank : 121)	θ value	0.47712 (rank : 255)
Query Neighborhood Hits	382	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI46_MOUSE
NC score	0.482294 (rank : 122)	θ value	0.0563607 (rank : 192)
Query Neighborhood Hits	382	Target Neighborhood Hits	287	Shared Neighborhood Hits	192
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.481364 (rank : 123)	θ value	0.0563607 (rank : 191)
Query Neighborhood Hits	382	Target Neighborhood Hits	291	Shared Neighborhood Hits	194
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI56_HUMAN
NC score	0.479382 (rank : 124)	θ value	0.00665767 (rank : 159)
Query Neighborhood Hits	382	Target Neighborhood Hits	339	Shared Neighborhood Hits	188
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
NC score	0.477236 (rank : 125)	θ value	0.00228821 (rank : 149)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	178
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RING1_HUMAN
NC score	0.473452 (rank : 126)	θ value	9.29e-05 (rank : 107)
Query Neighborhood Hits	382	Target Neighborhood Hits	219	Shared Neighborhood Hits	160
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.466059 (rank : 127)	θ value	9.29e-05 (rank : 108)
Query Neighborhood Hits	382	Target Neighborhood Hits	220	Shared Neighborhood Hits	161
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRIM9_HUMAN
NC score	0.456332 (rank : 128)	θ value	0.0736092 (rank : 197)
Query Neighborhood Hits	382	Target Neighborhood Hits	294	Shared Neighborhood Hits	177
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI36_HUMAN
NC score	0.450201 (rank : 129)	θ value	0.0252991 (rank : 176)
Query Neighborhood Hits	382	Target Neighborhood Hits	282	Shared Neighborhood Hits	176
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRIM9_MOUSE
NC score	0.450052 (rank : 130)	θ value	0.0736092 (rank : 198)
Query Neighborhood Hits	382	Target Neighborhood Hits	274	Shared Neighborhood Hits	173
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CHFR_HUMAN
NC score	0.447151 (rank : 131)	θ value	3.77169e-06 (rank : 98)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	176
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRI36_MOUSE
NC score	0.441760 (rank : 132)	θ value	0.125558 (rank : 214)
Query Neighborhood Hits	382	Target Neighborhood Hits	266	Shared Neighborhood Hits	174
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

RING2_MOUSE
NC score	0.441156 (rank : 133)	θ value	0.00175202 (rank : 145)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	157
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.441084 (rank : 134)	θ value	0.00175202 (rank : 144)
Query Neighborhood Hits	382	Target Neighborhood Hits	201	Shared Neighborhood Hits	157
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

CHFR_MOUSE
NC score	0.440419 (rank : 135)	θ value	2.88788e-06 (rank : 97)
Query Neighborhood Hits	382	Target Neighborhood Hits	264	Shared Neighborhood Hits	179
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RAG1_HUMAN
NC score	0.439189 (rank : 136)	θ value	0.00020696 (rank : 112)
Query Neighborhood Hits	382	Target Neighborhood Hits	203	Shared Neighborhood Hits	143
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN185_HUMAN
NC score	0.437189 (rank : 137)	θ value	0.00390308 (rank : 152)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	172
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.436267 (rank : 138)	θ value	0.00390308 (rank : 153)
Query Neighborhood Hits	382	Target Neighborhood Hits	211	Shared Neighborhood Hits	172
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN169_HUMAN
NC score	0.425480 (rank : 139)	θ value	1.87187e-05 (rank : 100)
Query Neighborhood Hits	382	Target Neighborhood Hits	203	Shared Neighborhood Hits	126
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RAG1_MOUSE
NC score	0.424936 (rank : 140)	θ value	0.00035302 (rank : 120)
Query Neighborhood Hits	382	Target Neighborhood Hits	189	Shared Neighborhood Hits	146
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RNF41_MOUSE
NC score	0.423558 (rank : 141)	θ value	0.0330416 (rank : 181)
Query Neighborhood Hits	382	Target Neighborhood Hits	224	Shared Neighborhood Hits	171
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.423466 (rank : 142)	θ value	0.0330416 (rank : 180)
Query Neighborhood Hits	382	Target Neighborhood Hits	226	Shared Neighborhood Hits	171
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF5_HUMAN
NC score	0.412595 (rank : 143)	θ value	0.0563607 (rank : 190)
Query Neighborhood Hits	382	Target Neighborhood Hits	206	Shared Neighborhood Hits	162
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.411781 (rank : 144)	θ value	0.0431538 (rank : 188)
Query Neighborhood Hits	382	Target Neighborhood Hits	206	Shared Neighborhood Hits	162
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RAD18_MOUSE
NC score	0.396980 (rank : 145)	θ value	0.000158464 (rank : 109)
Query Neighborhood Hits	382	Target Neighborhood Hits	230	Shared Neighborhood Hits	145
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RNF4_HUMAN
NC score	0.396117 (rank : 146)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	382	Target Neighborhood Hits	212	Shared Neighborhood Hits	161
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.390995 (rank : 147)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	382	Target Neighborhood Hits	212	Shared Neighborhood Hits	162
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RN183_HUMAN
NC score	0.374161 (rank : 148)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	109
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

DTX3_MOUSE
NC score	0.372341 (rank : 149)	θ value	0.00035302 (rank : 119)
Query Neighborhood Hits	382	Target Neighborhood Hits	202	Shared Neighborhood Hits	153
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RAD18_HUMAN
NC score	0.368788 (rank : 150)	θ value	0.000461057 (rank : 127)
Query Neighborhood Hits	382	Target Neighborhood Hits	284	Shared Neighborhood Hits	153
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

DTX3_HUMAN
NC score	0.363603 (rank : 151)	θ value	0.000461057 (rank : 126)
Query Neighborhood Hits	382	Target Neighborhood Hits	198	Shared Neighborhood Hits	150
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRAF6_MOUSE
NC score	0.363252 (rank : 152)	θ value	0.125558 (rank : 213)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	165
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF6_HUMAN
NC score	0.354514 (rank : 153)	θ value	0.125558 (rank : 212)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RN141_HUMAN
NC score	0.353732 (rank : 154)	θ value	0.163984 (rank : 222)
Query Neighborhood Hits	382	Target Neighborhood Hits	199	Shared Neighborhood Hits	151
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.352834 (rank : 155)	θ value	0.163984 (rank : 223)
Query Neighborhood Hits	382	Target Neighborhood Hits	200	Shared Neighborhood Hits	152
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

UHRF2_HUMAN
NC score	0.342341 (rank : 156)	θ value	0.00102713 (rank : 142)
Query Neighborhood Hits	382	Target Neighborhood Hits	269	Shared Neighborhood Hits	167
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.337993 (rank : 157)	θ value	0.000786445 (rank : 137)
Query Neighborhood Hits	382	Target Neighborhood Hits	275	Shared Neighborhood Hits	165
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TRI42_MOUSE
NC score	0.337811 (rank : 158)	θ value	1.06291 (rank : 274)
Query Neighborhood Hits	382	Target Neighborhood Hits	316	Shared Neighborhood Hits	127
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
NC score	0.329574 (rank : 159)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	382	Target Neighborhood Hits	283	Shared Neighborhood Hits	121
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

PML_HUMAN
NC score	0.324791 (rank : 160)	θ value	0.0252991 (rank : 172)
Query Neighborhood Hits	382	Target Neighborhood Hits	248	Shared Neighborhood Hits	123
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RN183_MOUSE
NC score	0.323494 (rank : 161)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	382	Target Neighborhood Hits	119	Shared Neighborhood Hits	104
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RFWD2_MOUSE
NC score	0.321516 (rank : 162)	θ value	0.00228821 (rank : 148)
Query Neighborhood Hits	382	Target Neighborhood Hits	535	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.321330 (rank : 163)	θ value	0.00228821 (rank : 147)
Query Neighborhood Hits	382	Target Neighborhood Hits	518	Shared Neighborhood Hits	193
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RN146_HUMAN
NC score	0.312421 (rank : 164)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	382	Target Neighborhood Hits	162	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

PCGF6_MOUSE
NC score	0.312398 (rank : 165)	θ value	0.0736092 (rank : 196)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	126
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.310602 (rank : 166)	θ value	0.0736092 (rank : 195)
Query Neighborhood Hits	382	Target Neighborhood Hits	178	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

SMRA3_HUMAN
NC score	0.310546 (rank : 167)	θ value	0.00665767 (rank : 158)
Query Neighborhood Hits	382	Target Neighborhood Hits	265	Shared Neighborhood Hits	185
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

RN146_MOUSE
NC score	0.310153 (rank : 168)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	382	Target Neighborhood Hits	161	Shared Neighborhood Hits	134
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

BIRC7_HUMAN
NC score	0.309858 (rank : 169)	θ value	1.38821 (rank : 276)
Query Neighborhood Hits	382	Target Neighborhood Hits	185	Shared Neighborhood Hits	145
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

R113A_HUMAN
NC score	0.301266 (rank : 170)	θ value	0.0193708 (rank : 168)
Query Neighborhood Hits	382	Target Neighborhood Hits	177	Shared Neighborhood Hits	129
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

PML_MOUSE
NC score	0.301116 (rank : 171)	θ value	0.0252991 (rank : 173)
Query Neighborhood Hits	382	Target Neighborhood Hits	246	Shared Neighborhood Hits	135
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

R113B_HUMAN
NC score	0.300506 (rank : 172)	θ value	0.62314 (rank : 258)
Query Neighborhood Hits	382	Target Neighborhood Hits	165	Shared Neighborhood Hits	126
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

TIF1G_HUMAN
NC score	0.296236 (rank : 173)	θ value	0.00102713 (rank : 140)
Query Neighborhood Hits	382	Target Neighborhood Hits	410	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.292154 (rank : 174)	θ value	0.000270298 (rank : 118)
Query Neighborhood Hits	382	Target Neighborhood Hits	498	Shared Neighborhood Hits	127
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PCGF4_MOUSE
NC score	0.291785 (rank : 175)	θ value	0.000786445 (rank : 136)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	124
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.291031 (rank : 176)	θ value	0.000786445 (rank : 135)
Query Neighborhood Hits	382	Target Neighborhood Hits	161	Shared Neighborhood Hits	127
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

SMRA3_MOUSE
NC score	0.290990 (rank : 177)	θ value	0.21417 (rank : 229)
Query Neighborhood Hits	382	Target Neighborhood Hits	267	Shared Neighborhood Hits	178
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

UHRF1_MOUSE
NC score	0.289047 (rank : 178)	θ value	0.000602161 (rank : 133)
Query Neighborhood Hits	382	Target Neighborhood Hits	278	Shared Neighborhood Hits	155
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PCGF2_MOUSE
NC score	0.284734 (rank : 179)	θ value	0.000602161 (rank : 130)
Query Neighborhood Hits	382	Target Neighborhood Hits	213	Shared Neighborhood Hits	122
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.284707 (rank : 180)	θ value	0.000602161 (rank : 129)
Query Neighborhood Hits	382	Target Neighborhood Hits	222	Shared Neighborhood Hits	122
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

UHRF1_HUMAN
NC score	0.276538 (rank : 181)	θ value	0.0252991 (rank : 177)
Query Neighborhood Hits	382	Target Neighborhood Hits	272	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

TRAF5_MOUSE
NC score	0.271569 (rank : 182)	θ value	0.000602161 (rank : 131)
Query Neighborhood Hits	382	Target Neighborhood Hits	355	Shared Neighborhood Hits	162
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRI45_HUMAN
NC score	0.268975 (rank : 183)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	112
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

CM007_MOUSE
NC score	0.266286 (rank : 184)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	382	Target Neighborhood Hits	416	Shared Neighborhood Hits	168
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

TIF1B_HUMAN
NC score	0.265962 (rank : 185)	θ value	0.0961366 (rank : 207)
Query Neighborhood Hits	382	Target Neighborhood Hits	312	Shared Neighborhood Hits	116
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.261373 (rank : 186)	θ value	0.0431538 (rank : 189)
Query Neighborhood Hits	382	Target Neighborhood Hits	276	Shared Neighborhood Hits	113
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

AMFR2_HUMAN
NC score	0.258890 (rank : 187)	θ value	0.000786445 (rank : 134)
Query Neighborhood Hits	382	Target Neighborhood Hits	219	Shared Neighborhood Hits	140
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.257102 (rank : 188)	θ value	0.00102713 (rank : 139)
Query Neighborhood Hits	382	Target Neighborhood Hits	208	Shared Neighborhood Hits	138
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

TRI45_MOUSE
NC score	0.256446 (rank : 189)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	105
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

PZRN3_MOUSE
NC score	0.254133 (rank : 190)	θ value	2.44474e-05 (rank : 103)
Query Neighborhood Hits	382	Target Neighborhood Hits	447	Shared Neighborhood Hits	183
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

LNX1_MOUSE
NC score	0.254082 (rank : 191)	θ value	1.06291 (rank : 270)
Query Neighborhood Hits	382	Target Neighborhood Hits	377	Shared Neighborhood Hits	162
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_HUMAN
NC score	0.253695 (rank : 192)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	382	Target Neighborhood Hits	379	Shared Neighborhood Hits	169
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TOPRS_MOUSE
NC score	0.253061 (rank : 193)	θ value	1.81305 (rank : 301)
Query Neighborhood Hits	382	Target Neighborhood Hits	263	Shared Neighborhood Hits	141
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

LNX2_MOUSE
NC score	0.251469 (rank : 194)	θ value	0.163984 (rank : 218)
Query Neighborhood Hits	382	Target Neighborhood Hits	407	Shared Neighborhood Hits	174
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.250229 (rank : 195)	θ value	0.279714 (rank : 231)
Query Neighborhood Hits	382	Target Neighborhood Hits	389	Shared Neighborhood Hits	171
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

PZRN3_HUMAN
NC score	0.250014 (rank : 196)	θ value	5.44631e-05 (rank : 106)
Query Neighborhood Hits	382	Target Neighborhood Hits	461	Shared Neighborhood Hits	182
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

TOPRS_HUMAN
NC score	0.249612 (rank : 197)	θ value	1.81305 (rank : 300)
Query Neighborhood Hits	382	Target Neighborhood Hits	286	Shared Neighborhood Hits	143
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF5_HUMAN
NC score	0.248478 (rank : 198)	θ value	0.00390308 (rank : 154)
Query Neighborhood Hits	382	Target Neighborhood Hits	396	Shared Neighborhood Hits	163
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

PZRN4_HUMAN
NC score	0.238161 (rank : 199)	θ value	0.813845 (rank : 264)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	183
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

CM007_HUMAN
NC score	0.237511 (rank : 200)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	382	Target Neighborhood Hits	422	Shared Neighborhood Hits	167
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

TRAF4_HUMAN
NC score	0.232498 (rank : 201)	θ value	0.62314 (rank : 260)
Query Neighborhood Hits	382	Target Neighborhood Hits	373	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

RBBP6_MOUSE
NC score	0.222859 (rank : 202)	θ value	0.00020696 (rank : 114)
Query Neighborhood Hits	382	Target Neighborhood Hits	1014	Shared Neighborhood Hits	165
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TRAIP_HUMAN
NC score	0.214248 (rank : 203)	θ value	0.00020696 (rank : 115)
Query Neighborhood Hits	382	Target Neighborhood Hits	780	Shared Neighborhood Hits	172
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

DTX3L_HUMAN
NC score	0.212100 (rank : 204)	θ value	0.0330416 (rank : 178)
Query Neighborhood Hits	382	Target Neighborhood Hits	187	Shared Neighborhood Hits	124
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TRAF7_HUMAN
NC score	0.208789 (rank : 205)	θ value	0.0252991 (rank : 174)
Query Neighborhood Hits	382	Target Neighborhood Hits	482	Shared Neighborhood Hits	164
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
NC score	0.208169 (rank : 206)	θ value	0.0252991 (rank : 175)
Query Neighborhood Hits	382	Target Neighborhood Hits	470	Shared Neighborhood Hits	161
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

CBLC_MOUSE
NC score	0.206117 (rank : 207)	θ value	0.0736092 (rank : 193)
Query Neighborhood Hits	382	Target Neighborhood Hits	186	Shared Neighborhood Hits	147
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBLC_HUMAN
NC score	0.205297 (rank : 208)	θ value	0.0431538 (rank : 184)
Query Neighborhood Hits	382	Target Neighborhood Hits	173	Shared Neighborhood Hits	142
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBL_HUMAN
NC score	0.204649 (rank : 209)	θ value	0.0961366 (rank : 199)
Query Neighborhood Hits	382	Target Neighborhood Hits	353	Shared Neighborhood Hits	161
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

RBBP6_HUMAN
NC score	0.203401 (rank : 210)	θ value	0.00020696 (rank : 113)
Query Neighborhood Hits	382	Target Neighborhood Hits	1135	Shared Neighborhood Hits	175
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CBL_MOUSE
NC score	0.200574 (rank : 211)	θ value	0.0961366 (rank : 200)
Query Neighborhood Hits	382	Target Neighborhood Hits	426	Shared Neighborhood Hits	165
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

TIF1A_HUMAN
NC score	0.199588 (rank : 212)	θ value	0.365318 (rank : 246)
Query Neighborhood Hits	382	Target Neighborhood Hits	327	Shared Neighborhood Hits	105
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

CBLB_MOUSE
NC score	0.199243 (rank : 213)	θ value	0.365318 (rank : 238)
Query Neighborhood Hits	382	Target Neighborhood Hits	277	Shared Neighborhood Hits	154
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.198218 (rank : 214)	θ value	0.365318 (rank : 237)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	154
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TRAIP_MOUSE
NC score	0.197819 (rank : 215)	θ value	0.000158464 (rank : 110)
Query Neighborhood Hits	382	Target Neighborhood Hits	745	Shared Neighborhood Hits	166
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

RC3H1_MOUSE
NC score	0.195160 (rank : 216)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	382	Target Neighborhood Hits	244	Shared Neighborhood Hits	128
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

NHLC1_MOUSE
NC score	0.193860 (rank : 217)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	382	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RN152_MOUSE
NC score	0.192120 (rank : 218)	θ value	8.99809 (rank : 382)
Query Neighborhood Hits	382	Target Neighborhood Hits	109	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRAF2_HUMAN
NC score	0.191915 (rank : 219)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	382	Target Neighborhood Hits	402	Shared Neighborhood Hits	135
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

NHLC1_HUMAN
NC score	0.189982 (rank : 220)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	382	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRAF3_MOUSE
NC score	0.189935 (rank : 221)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	382	Target Neighborhood Hits	476	Shared Neighborhood Hits	184
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF2_MOUSE
NC score	0.189682 (rank : 222)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	382	Target Neighborhood Hits	394	Shared Neighborhood Hits	132
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

RN152_HUMAN
NC score	0.188109 (rank : 223)	θ value	8.99809 (rank : 381)
Query Neighborhood Hits	382	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RC3H1_HUMAN
NC score	0.187644 (rank : 224)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	382	Target Neighborhood Hits	433	Shared Neighborhood Hits	131
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

BT3A2_HUMAN
NC score	0.185550 (rank : 225)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	382	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

TRAF3_HUMAN
NC score	0.183993 (rank : 226)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	382	Target Neighborhood Hits	463	Shared Neighborhood Hits	172
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

BTNL1_MOUSE
NC score	0.177071 (rank : 227)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

TIF1A_MOUSE
NC score	0.176000 (rank : 228)	θ value	0.279714 (rank : 232)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	93
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

BTNL2_HUMAN
NC score	0.171061 (rank : 229)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	382	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

RNF34_MOUSE
NC score	0.165953 (rank : 230)	θ value	0.21417 (rank : 228)
Query Neighborhood Hits	382	Target Neighborhood Hits	160	Shared Neighborhood Hits	87
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

MOG_HUMAN
NC score	0.165524 (rank : 231)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	382	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
NC score	0.164983 (rank : 232)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	382	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

RNF32_HUMAN
NC score	0.164657 (rank : 233)	θ value	1.38821 (rank : 289)
Query Neighborhood Hits	382	Target Neighborhood Hits	133	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF34_HUMAN
NC score	0.164263 (rank : 234)	θ value	0.21417 (rank : 227)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	87
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

BARD1_HUMAN
NC score	0.161990 (rank : 235)	θ value	0.00134147 (rank : 143)
Query Neighborhood Hits	382	Target Neighborhood Hits	427	Shared Neighborhood Hits	107
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
NC score	0.158794 (rank : 236)	θ value	0.000602161 (rank : 128)
Query Neighborhood Hits	382	Target Neighborhood Hits	411	Shared Neighborhood Hits	99
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

TRAF4_MOUSE
NC score	0.156325 (rank : 237)	θ value	0.163984 (rank : 224)
Query Neighborhood Hits	382	Target Neighborhood Hits	338	Shared Neighborhood Hits	113
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

RKHD1_HUMAN
NC score	0.155408 (rank : 238)	θ value	0.365318 (rank : 245)
Query Neighborhood Hits	382	Target Neighborhood Hits	163	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC8_HUMAN
NC score	0.152390 (rank : 239)	θ value	0.21417 (rank : 226)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	89
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

ARD1_MOUSE
NC score	0.152267 (rank : 240)	θ value	0.00020696 (rank : 111)
Query Neighborhood Hits	382	Target Neighborhood Hits	573	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

PJA1_HUMAN
NC score	0.149798 (rank : 241)	θ value	0.365318 (rank : 243)
Query Neighborhood Hits	382	Target Neighborhood Hits	159	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

ARD1_HUMAN
NC score	0.148034 (rank : 242)	θ value	0.000461057 (rank : 124)
Query Neighborhood Hits	382	Target Neighborhood Hits	621	Shared Neighborhood Hits	83
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

RNF32_MOUSE
NC score	0.147985 (rank : 243)	θ value	2.36792 (rank : 310)
Query Neighborhood Hits	382	Target Neighborhood Hits	129	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

MNAB_HUMAN
NC score	0.146612 (rank : 244)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	382	Target Neighborhood Hits	196	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

RN167_MOUSE
NC score	0.145670 (rank : 245)	θ value	0.0113563 (rank : 164)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	88
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

BRE1B_MOUSE
NC score	0.145455 (rank : 246)	θ value	0.163984 (rank : 216)
Query Neighborhood Hits	382	Target Neighborhood Hits	970	Shared Neighborhood Hits	228
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MNAB_MOUSE
NC score	0.144819 (rank : 247)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	382	Target Neighborhood Hits	231	Shared Neighborhood Hits	109
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

BRE1B_HUMAN
NC score	0.144326 (rank : 248)	θ value	0.163984 (rank : 215)
Query Neighborhood Hits	382	Target Neighborhood Hits	1040	Shared Neighborhood Hits	232
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRAP_HUMAN
NC score	0.141904 (rank : 249)	θ value	0.00298849 (rank : 150)
Query Neighborhood Hits	382	Target Neighborhood Hits	560	Shared Neighborhood Hits	145
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

RN167_HUMAN
NC score	0.140841 (rank : 250)	θ value	0.0113563 (rank : 163)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_HUMAN
NC score	0.137629 (rank : 251)	θ value	0.00298849 (rank : 151)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	78
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

UB7I3_MOUSE
NC score	0.135422 (rank : 252)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	382	Target Neighborhood Hits	131	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RN123_MOUSE
NC score	0.134689 (rank : 253)	θ value	0.47712 (rank : 253)
Query Neighborhood Hits	382	Target Neighborhood Hits	174	Shared Neighborhood Hits	124
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_HUMAN
NC score	0.132922 (rank : 254)	θ value	0.47712 (rank : 252)
Query Neighborhood Hits	382	Target Neighborhood Hits	175	Shared Neighborhood Hits	124
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RNF13_MOUSE
NC score	0.132842 (rank : 255)	θ value	0.00869519 (rank : 160)
Query Neighborhood Hits	382	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RFFL_HUMAN
NC score	0.132659 (rank : 256)	θ value	0.0961366 (rank : 201)
Query Neighborhood Hits	382	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

MAT1_HUMAN
NC score	0.131241 (rank : 257)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	382	Target Neighborhood Hits	179	Shared Neighborhood Hits	68
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

PJA1_MOUSE
NC score	0.130615 (rank : 258)	θ value	0.163984 (rank : 221)
Query Neighborhood Hits	382	Target Neighborhood Hits	145	Shared Neighborhood Hits	74
SwissProt Accessions	O55176, Q8CFU2, Q99MJ1, Q99MJ2, Q99MJ3, Q9DB04	Gene names	Pja1
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-).

RFFL_MOUSE
NC score	0.129929 (rank : 259)	θ value	0.0961366 (rank : 202)
Query Neighborhood Hits	382	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

MAT1_MOUSE
NC score	0.127937 (rank : 260)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	382	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

BRAP_MOUSE
NC score	0.125031 (rank : 261)	θ value	0.365318 (rank : 234)
Query Neighborhood Hits	382	Target Neighborhood Hits	409	Shared Neighborhood Hits	120
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

MGRN1_MOUSE
NC score	0.122974 (rank : 262)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	382	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RNF38_HUMAN
NC score	0.122884 (rank : 263)	θ value	0.00509761 (rank : 156)
Query Neighborhood Hits	382	Target Neighborhood Hits	155	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0F5, Q8N0Y0	Gene names	RNF38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

MGRN1_HUMAN
NC score	0.121673 (rank : 264)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	382	Target Neighborhood Hits	192	Shared Neighborhood Hits	104
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

RNF38_MOUSE
NC score	0.120674 (rank : 265)	θ value	0.00509761 (rank : 157)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BI21, Q6P5B1	Gene names	Rnf38
Domain Architecture	No domain graphic available
Description	RING finger protein 38.

BRE1A_HUMAN
NC score	0.118785 (rank : 266)	θ value	0.365318 (rank : 235)
Query Neighborhood Hits	382	Target Neighborhood Hits	1071	Shared Neighborhood Hits	217
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
NC score	0.118187 (rank : 267)	θ value	0.365318 (rank : 236)
Query Neighborhood Hits	382	Target Neighborhood Hits	1025	Shared Neighborhood Hits	215
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BIRC3_HUMAN
NC score	0.117909 (rank : 268)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	382	Target Neighborhood Hits	133	Shared Neighborhood Hits	88
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

RN122_HUMAN
NC score	0.116715 (rank : 269)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BIRC2_HUMAN
NC score	0.113446 (rank : 270)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	382	Target Neighborhood Hits	142	Shared Neighborhood Hits	94
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

UB7I3_HUMAN
NC score	0.113396 (rank : 271)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	382	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RN165_HUMAN
NC score	0.111996 (rank : 272)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

ZN364_HUMAN
NC score	0.111267 (rank : 273)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y4L5, Q5T2V9, Q7Z2J2	Gene names	ZNF364, RNF115
Domain Architecture	No domain graphic available
Description	Zinc finger protein 364 (Rabring 7) (RING finger protein 115).

RN122_MOUSE
NC score	0.109916 (rank : 274)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	382	Target Neighborhood Hits	121	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

BIRC2_MOUSE
NC score	0.107738 (rank : 275)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

RNF26_HUMAN
NC score	0.106589 (rank : 276)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	382	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

NEUL1_HUMAN
NC score	0.105661 (rank : 277)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	382	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

FSD1L_MOUSE
NC score	0.105442 (rank : 278)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	382	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

NEURL_MOUSE
NC score	0.104448 (rank : 279)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	382	Target Neighborhood Hits	106	Shared Neighborhood Hits	67
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

ZN364_MOUSE
NC score	0.104426 (rank : 280)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q9D0C1, Q8R5A1, Q9D885	Gene names	Znf364, Zfp364
Domain Architecture
Description	Zinc finger protein 364 (Rabring 7).

RN126_MOUSE
NC score	0.104176 (rank : 281)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	89
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TRI66_MOUSE
NC score	0.102957 (rank : 282)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	382	Target Neighborhood Hits	491	Shared Neighborhood Hits	83
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RN103_HUMAN
NC score	0.102151 (rank : 283)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	382	Target Neighborhood Hits	153	Shared Neighborhood Hits	81
SwissProt Accessions	O00237, Q8IVB9	Gene names	RNF103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103 homolog) (Zfp-103) (KF-1) (hKF-1).

RN103_MOUSE
NC score	0.101741 (rank : 284)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	382	Target Neighborhood Hits	143	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R1W3, O08670, O08883	Gene names	Rnf103, Zfp103
Domain Architecture	No domain graphic available
Description	RING finger protein 103 (Zinc finger protein 103) (Zfp-103) (KF-1) (mKF-1).

BIRC3_MOUSE
NC score	0.100550 (rank : 285)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	382	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

ZSWM2_HUMAN
NC score	0.099477 (rank : 286)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	382	Target Neighborhood Hits	151	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

TRI66_HUMAN
NC score	0.098639 (rank : 287)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	382	Target Neighborhood Hits	479	Shared Neighborhood Hits	76
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RNF24_MOUSE
NC score	0.098628 (rank : 288)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	382	Target Neighborhood Hits	124	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BGI1	Gene names	Rnf24
Domain Architecture	No domain graphic available
Description	RING finger protein 24.

RNF24_HUMAN
NC score	0.097872 (rank : 289)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	382	Target Neighborhood Hits	122	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y225, Q9UMH1	Gene names	RNF24
Domain Architecture
Description	RING finger protein 24.

CNOT4_HUMAN
NC score	0.097294 (rank : 290)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	382	Target Neighborhood Hits	207	Shared Neighborhood Hits	43
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CD276_MOUSE
NC score	0.095538 (rank : 291)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	382	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

RN126_HUMAN
NC score	0.095107 (rank : 292)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	382	Target Neighborhood Hits	126	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

MIB1_HUMAN
NC score	0.093870 (rank : 293)	θ value	0.0431538 (rank : 185)
Query Neighborhood Hits	382	Target Neighborhood Hits	470	Shared Neighborhood Hits	113
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.093734 (rank : 294)	θ value	0.0431538 (rank : 186)
Query Neighborhood Hits	382	Target Neighborhood Hits	471	Shared Neighborhood Hits	113
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

FSD1L_HUMAN
NC score	0.093661 (rank : 295)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	382	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

RN139_HUMAN
NC score	0.093192 (rank : 296)	θ value	0.62314 (rank : 259)
Query Neighborhood Hits	382	Target Neighborhood Hits	130	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WU17, O75485, Q7LDL3	Gene names	RNF139, TRC8
Domain Architecture	No domain graphic available
Description	RING finger protein 139 (Translocation in renal carcinoma on chromosome 8).

CNOT4_MOUSE
NC score	0.092786 (rank : 297)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	382	Target Neighborhood Hits	277	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RN139_MOUSE
NC score	0.092498 (rank : 298)	θ value	0.47712 (rank : 254)
Query Neighborhood Hits	382	Target Neighborhood Hits	131	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TMV1, Q8BZU9	Gene names	Rnf139
Domain Architecture	No domain graphic available
Description	RING finger protein 139.

TTC3_HUMAN
NC score	0.089701 (rank : 299)	θ value	0.47712 (rank : 256)
Query Neighborhood Hits	382	Target Neighborhood Hits	664	Shared Neighborhood Hits	128
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

MKRN4_HUMAN
NC score	0.088887 (rank : 300)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	91
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

DZIP3_MOUSE
NC score	0.088854 (rank : 301)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	382	Target Neighborhood Hits	414	Shared Neighborhood Hits	129
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

MKRN2_MOUSE
NC score	0.087569 (rank : 302)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	382	Target Neighborhood Hits	130	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

RNF19_MOUSE
NC score	0.086492 (rank : 303)	θ value	0.125558 (rank : 210)
Query Neighborhood Hits	382	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.086396 (rank : 304)	θ value	0.125558 (rank : 209)
Query Neighborhood Hits	382	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

PEX2_MOUSE
NC score	0.085885 (rank : 305)	θ value	6.88961 (rank : 362)
Query Neighborhood Hits	382	Target Neighborhood Hits	57	Shared Neighborhood Hits	51
SwissProt Accessions	P55098, O35467	Gene names	Pxmp3, Paf1, Pex2, Pmp35
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3).

CD276_HUMAN
NC score	0.085665 (rank : 306)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	382	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

MKRN2_HUMAN
NC score	0.085204 (rank : 307)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	382	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

ICOSL_HUMAN
NC score	0.084883 (rank : 308)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

DZIP3_HUMAN
NC score	0.084643 (rank : 309)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	382	Target Neighborhood Hits	399	Shared Neighborhood Hits	125
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RNF12_MOUSE
NC score	0.083844 (rank : 310)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	382	Target Neighborhood Hits	159	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

LRSM1_HUMAN
NC score	0.082267 (rank : 311)	θ value	6.88961 (rank : 361)
Query Neighborhood Hits	382	Target Neighborhood Hits	1078	Shared Neighborhood Hits	174
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

GOLI_MOUSE
NC score	0.082050 (rank : 312)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

GOLI_HUMAN
NC score	0.081633 (rank : 313)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	71
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

ZSWM2_MOUSE
NC score	0.081311 (rank : 314)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	382	Target Neighborhood Hits	132	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

MYLIP_HUMAN
NC score	0.080725 (rank : 315)	θ value	0.0252991 (rank : 171)
Query Neighborhood Hits	382	Target Neighborhood Hits	162	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MKRN3_HUMAN
NC score	0.080714 (rank : 316)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	382	Target Neighborhood Hits	165	Shared Neighborhood Hits	78
SwissProt Accessions	Q13064	Gene names	MKRN3, RNF63, ZNF127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127) (RING finger protein 63).

RNF12_HUMAN
NC score	0.077261 (rank : 317)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	382	Target Neighborhood Hits	173	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVW2, Q9Y598	Gene names	RNF12, RLIM
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (NY-REN-43 antigen).

PDL1_MOUSE
NC score	0.077057 (rank : 318)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	382	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

CP250_HUMAN
NC score	0.076684 (rank : 319)	θ value	0.365318 (rank : 240)
Query Neighborhood Hits	382	Target Neighborhood Hits	1805	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGB1_HUMAN
NC score	0.076396 (rank : 320)	θ value	0.0148317 (rank : 167)
Query Neighborhood Hits	382	Target Neighborhood Hits	2297	Shared Neighborhood Hits	190
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SIAH2_HUMAN
NC score	0.076338 (rank : 321)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	382	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	O43255, O43270	Gene names	SIAH2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (hSiah2).

SIAH2_MOUSE
NC score	0.075462 (rank : 322)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	382	Target Neighborhood Hits	101	Shared Neighborhood Hits	59
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

CAF1A_MOUSE
NC score	0.075102 (rank : 323)	θ value	0.000461057 (rank : 125)
Query Neighborhood Hits	382	Target Neighborhood Hits	736	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

GOGA4_MOUSE
NC score	0.073404 (rank : 324)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	382	Target Neighborhood Hits	1939	Shared Neighborhood Hits	173
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LRSM1_MOUSE
NC score	0.073174 (rank : 325)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	382	Target Neighborhood Hits	874	Shared Neighborhood Hits	159
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CD86_HUMAN
NC score	0.072755 (rank : 326)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

HHLA2_HUMAN
NC score	0.072272 (rank : 327)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	382	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

MIB2_HUMAN
NC score	0.071602 (rank : 328)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	100
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

SYCP1_MOUSE
NC score	0.070814 (rank : 329)	θ value	0.21417 (rank : 230)
Query Neighborhood Hits	382	Target Neighborhood Hits	1456	Shared Neighborhood Hits	149
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

GCC1_HUMAN
NC score	0.070041 (rank : 330)	θ value	1.81305 (rank : 295)
Query Neighborhood Hits	382	Target Neighborhood Hits	887	Shared Neighborhood Hits	117
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

RN175_HUMAN
NC score	0.069990 (rank : 331)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	382	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N4F7	Gene names	RNF175
Domain Architecture	No domain graphic available
Description	RING finger protein 175.

CENPF_HUMAN
NC score	0.069283 (rank : 332)	θ value	1.81305 (rank : 293)
Query Neighborhood Hits	382	Target Neighborhood Hits	1932	Shared Neighborhood Hits	177
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MKRN3_MOUSE
NC score	0.068978 (rank : 333)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	382	Target Neighborhood Hits	137	Shared Neighborhood Hits	67
SwissProt Accessions	Q60764, Q7TQE4	Gene names	Mkrn3, Zfp127, Znf127
Domain Architecture
Description	Makorin-3 (Zinc finger protein 127).

RNF6_HUMAN
NC score	0.068783 (rank : 334)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	382	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y252, Q9UF41	Gene names	RNF6
Domain Architecture
Description	RING finger protein 6 (RING-H2 protein).

CD86_MOUSE
NC score	0.068164 (rank : 335)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

RN133_HUMAN
NC score	0.068149 (rank : 336)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	382	Target Neighborhood Hits	108	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

CF060_HUMAN
NC score	0.068140 (rank : 337)	θ value	1.81305 (rank : 294)
Query Neighborhood Hits	382	Target Neighborhood Hits	1270	Shared Neighborhood Hits	143
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CCD41_MOUSE
NC score	0.067761 (rank : 338)	θ value	1.06291 (rank : 266)
Query Neighborhood Hits	382	Target Neighborhood Hits	1399	Shared Neighborhood Hits	148
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_HUMAN
NC score	0.067489 (rank : 339)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	382	Target Neighborhood Hits	1430	Shared Neighborhood Hits	162
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MKRN1_HUMAN
NC score	0.067345 (rank : 340)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	382	Target Neighborhood Hits	141	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UHC7, Q6GSF1, Q9H0G0, Q9UEZ7	Gene names	MKRN1, RNF61
Domain Architecture
Description	Makorin-1 (RING finger protein 61).

ICOSL_MOUSE
NC score	0.067000 (rank : 341)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	382	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

NIN_HUMAN
NC score	0.066839 (rank : 342)	θ value	0.365318 (rank : 241)
Query Neighborhood Hits	382	Target Neighborhood Hits	1416	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

CP250_MOUSE
NC score	0.066703 (rank : 343)	θ value	0.163984 (rank : 217)
Query Neighborhood Hits	382	Target Neighborhood Hits	1583	Shared Neighborhood Hits	158
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

PDL2_HUMAN
NC score	0.066529 (rank : 344)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	382	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

BIRC4_HUMAN
NC score	0.066237 (rank : 345)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	382	Target Neighborhood Hits	89	Shared Neighborhood Hits	54
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

RNF11_HUMAN
NC score	0.065986 (rank : 346)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	382	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y3C5	Gene names	RNF11
Domain Architecture
Description	RING finger protein 11 (Sid 1669).

PCNT_HUMAN
NC score	0.065977 (rank : 347)	θ value	0.813845 (rank : 263)
Query Neighborhood Hits	382	Target Neighborhood Hits	1551	Shared Neighborhood Hits	146
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

MKRN1_MOUSE
NC score	0.065794 (rank : 348)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	382	Target Neighborhood Hits	141	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXP6	Gene names	Mkrn1
Domain Architecture
Description	Makorin-1.

RNF11_MOUSE
NC score	0.065733 (rank : 349)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	382	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QYK7, Q9EQI1	Gene names	Rnf11, N4wbp2, Sid1669
Domain Architecture
Description	RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669).

GCC2_MOUSE
NC score	0.065720 (rank : 350)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	382	Target Neighborhood Hits	1619	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CCD46_MOUSE
NC score	0.065523 (rank : 351)	θ value	0.365318 (rank : 239)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	150
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

BIRC4_MOUSE
NC score	0.065521 (rank : 352)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	382	Target Neighborhood Hits	89	Shared Neighborhood Hits	53
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

GOGA4_HUMAN
NC score	0.065470 (rank : 353)	θ value	1.38821 (rank : 285)
Query Neighborhood Hits	382	Target Neighborhood Hits	2034	Shared Neighborhood Hits	180
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

TRHY_HUMAN
NC score	0.064360 (rank : 354)	θ value	0.62314 (rank : 261)
Query Neighborhood Hits	382	Target Neighborhood Hits	1385	Shared Neighborhood Hits	124
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

NUMA1_HUMAN
NC score	0.064125 (rank : 355)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	382	Target Neighborhood Hits	1523	Shared Neighborhood Hits	149
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CROCC_MOUSE
NC score	0.064108 (rank : 356)	θ value	1.38821 (rank : 281)
Query Neighborhood Hits	382	Target Neighborhood Hits	1460	Shared Neighborhood Hits	141
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ARI2_HUMAN
NC score	0.064053 (rank : 357)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	382	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

MIB2_MOUSE
NC score	0.063788 (rank : 358)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	382	Target Neighborhood Hits	409	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PDL2_MOUSE
NC score	0.062857 (rank : 359)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	382	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

CE290_HUMAN
NC score	0.062824 (rank : 360)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	382	Target Neighborhood Hits	1553	Shared Neighborhood Hits	162
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPE_HUMAN
NC score	0.062477 (rank : 361)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	382	Target Neighborhood Hits	2060	Shared Neighborhood Hits	175
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD41_HUMAN
NC score	0.061845 (rank : 362)	θ value	1.38821 (rank : 277)
Query Neighborhood Hits	382	Target Neighborhood Hits	1139	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

ARI2_MOUSE
NC score	0.061819 (rank : 363)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	382	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

NIN_MOUSE
NC score	0.061544 (rank : 364)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	382	Target Neighborhood Hits	1376	Shared Neighborhood Hits	142
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

INCE_HUMAN
NC score	0.061455 (rank : 365)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	382	Target Neighborhood Hits	978	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

AZI1_MOUSE
NC score	0.061187 (rank : 366)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	382	Target Neighborhood Hits	990	Shared Neighborhood Hits	119
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

IBRD3_HUMAN
NC score	0.060476 (rank : 367)	θ value	0.47712 (rank : 249)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

TPR_HUMAN
NC score	0.060170 (rank : 368)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	382	Target Neighborhood Hits	1921	Shared Neighborhood Hits	156
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GCC1_MOUSE
NC score	0.059862 (rank : 369)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	382	Target Neighborhood Hits	777	Shared Neighborhood Hits	109
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MYLIP_MOUSE
NC score	0.059178 (rank : 370)	θ value	0.0736092 (rank : 194)
Query Neighborhood Hits	382	Target Neighborhood Hits	139	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

AZI1_HUMAN
NC score	0.059149 (rank : 371)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	382	Target Neighborhood Hits	1000	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

SIA1B_MOUSE
NC score	0.059034 (rank : 372)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	382	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q06985, Q7TPV6	Gene names	Siah1b
Domain Architecture
Description	Ubiquitin ligase SIAH1B (EC 6.3.2.-) (Seven in absentia homolog 1b) (Siah1b) (Siah-1b).

PDL1_HUMAN
NC score	0.058855 (rank : 373)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	382	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

FLIP1_MOUSE
NC score	0.058845 (rank : 374)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	382	Target Neighborhood Hits	1176	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

SDCG8_HUMAN
NC score	0.058722 (rank : 375)	θ value	2.36792 (rank : 311)
Query Neighborhood Hits	382	Target Neighborhood Hits	1002	Shared Neighborhood Hits	126
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

AKAP9_HUMAN
NC score	0.058635 (rank : 376)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	382	Target Neighborhood Hits	1710	Shared Neighborhood Hits	140
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SDCG8_MOUSE
NC score	0.058492 (rank : 377)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	382	Target Neighborhood Hits	886	Shared Neighborhood Hits	114
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

EEA1_HUMAN
NC score	0.058438 (rank : 378)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	382	Target Neighborhood Hits	1796	Shared Neighborhood Hits	165
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

SIAH1_HUMAN
NC score	0.058261 (rank : 379)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	382	Target Neighborhood Hits	72	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IUQ4, O43269, Q92880	Gene names	SIAH1, HUMSIAH
Domain Architecture
Description	Ubiquitin ligase SIAH1 (EC 6.3.2.-) (Seven in absentia homolog 1) (Siah-1) (Siah-1a).

FLIP1_HUMAN
NC score	0.058243 (rank : 380)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	145
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

LRC45_MOUSE
NC score	0.058134 (rank : 381)	θ value	0.163984 (rank : 219)
Query Neighborhood Hits	382	Target Neighborhood Hits	959	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

UACA_HUMAN
NC score	0.058108 (rank : 382)	θ value	1.06291 (rank : 275)
Query Neighborhood Hits	382	Target Neighborhood Hits	1622	Shared Neighborhood Hits	145
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RBP24_HUMAN
NC score	0.058084 (rank : 383)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	382	Target Neighborhood Hits	1559	Shared Neighborhood Hits	156
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GOGA3_HUMAN
NC score	0.057999 (rank : 384)	θ value	2.36792 (rank : 305)
Query Neighborhood Hits	382	Target Neighborhood Hits	1317	Shared Neighborhood Hits	132
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

RABE1_MOUSE
NC score	0.057975 (rank : 385)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	382	Target Neighborhood Hits	1105	Shared Neighborhood Hits	128
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

GCC2_HUMAN
NC score	0.057833 (rank : 386)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	382	Target Neighborhood Hits	1558	Shared Neighborhood Hits	156
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

SIA1A_MOUSE
NC score	0.057639 (rank : 387)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	382	Target Neighborhood Hits	72	Shared Neighborhood Hits	55
SwissProt Accessions	P61092, Q06984	Gene names	Siah1a
Domain Architecture
Description	Ubiquitin ligase SIAH1A (EC 6.3.2.-) (Seven in absentia homolog 1a) (Siah1a) (Siah-1a) (mSiah-1a).

CROCC_HUMAN
NC score	0.057604 (rank : 388)	θ value	5.27518 (rank : 341)
Query Neighborhood Hits	382	Target Neighborhood Hits	1409	Shared Neighborhood Hits	141
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SMC3_MOUSE
NC score	0.057397 (rank : 389)	θ value	0.0113563 (rank : 166)
Query Neighborhood Hits	382	Target Neighborhood Hits	1187	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

RB6I2_HUMAN
NC score	0.057390 (rank : 390)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	382	Target Neighborhood Hits	1584	Shared Neighborhood Hits	148
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SMC3_HUMAN
NC score	0.057368 (rank : 391)	θ value	0.0113563 (rank : 165)
Query Neighborhood Hits	382	Target Neighborhood Hits	1186	Shared Neighborhood Hits	117
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

MY18A_HUMAN
NC score	0.057164 (rank : 392)	θ value	1.38821 (rank : 288)
Query Neighborhood Hits	382	Target Neighborhood Hits	1929	Shared Neighborhood Hits	165
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CI093_HUMAN
NC score	0.056469 (rank : 393)	θ value	1.38821 (rank : 279)
Query Neighborhood Hits	382	Target Neighborhood Hits	1088	Shared Neighborhood Hits	124
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

RB6I2_MOUSE
NC score	0.056291 (rank : 394)	θ value	8.99809 (rank : 380)
Query Neighborhood Hits	382	Target Neighborhood Hits	1433	Shared Neighborhood Hits	141
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RABE1_HUMAN
NC score	0.056187 (rank : 395)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	382	Target Neighborhood Hits	1104	Shared Neighborhood Hits	127
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CT2NL_HUMAN
NC score	0.056048 (rank : 396)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	382	Target Neighborhood Hits	1059	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

PEX2_HUMAN
NC score	0.055861 (rank : 397)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	382	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	P28328, Q567S6, Q9BW41	Gene names	PXMP3, PAF1, PEX2, PMP3, PMP35, RNF72
Domain Architecture
Description	Peroxisome assembly factor 1 (PAF-1) (Peroxin-2) (Peroxisomal membrane protein 3) (35 kDa peroxisomal membrane protein) (RING finger protein 72).

ANR26_HUMAN
NC score	0.055752 (rank : 398)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	382	Target Neighborhood Hits	1614	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CING_MOUSE
NC score	0.055688 (rank : 399)	θ value	8.99809 (rank : 370)
Query Neighborhood Hits	382	Target Neighborhood Hits	1432	Shared Neighborhood Hits	137
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

REST_HUMAN
NC score	0.055551 (rank : 400)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	382	Target Neighborhood Hits	1605	Shared Neighborhood Hits	153
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

INCE_MOUSE
NC score	0.055454 (rank : 401)	θ value	1.38821 (rank : 286)
Query Neighborhood Hits	382	Target Neighborhood Hits	903	Shared Neighborhood Hits	105
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

CCD11_HUMAN
NC score	0.055381 (rank : 402)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	382	Target Neighborhood Hits	822	Shared Neighborhood Hits	106
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

GOGA6_HUMAN
NC score	0.055290 (rank : 403)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	382	Target Neighborhood Hits	1007	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

HMMR_MOUSE
NC score	0.055115 (rank : 404)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	382	Target Neighborhood Hits	1178	Shared Neighborhood Hits	126
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RNF37_MOUSE
NC score	0.055004 (rank : 405)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	382	Target Neighborhood Hits	102	Shared Neighborhood Hits	55
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

SYCP1_HUMAN
NC score	0.054935 (rank : 406)	θ value	6.88961 (rank : 365)
Query Neighborhood Hits	382	Target Neighborhood Hits	1313	Shared Neighborhood Hits	131
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRIPB_HUMAN
NC score	0.054904 (rank : 407)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	382	Target Neighborhood Hits	1587	Shared Neighborhood Hits	148
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CN145_MOUSE
NC score	0.054692 (rank : 408)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	382	Target Neighborhood Hits	916	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

HMMR_HUMAN
NC score	0.054381 (rank : 409)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	382	Target Neighborhood Hits	1082	Shared Neighborhood Hits	121
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

SMC2_HUMAN
NC score	0.054361 (rank : 410)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	382	Target Neighborhood Hits	1405	Shared Neighborhood Hits	135
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

GOGA3_MOUSE
NC score	0.054200 (rank : 411)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	382	Target Neighborhood Hits	1437	Shared Neighborhood Hits	144
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

IFT74_MOUSE
NC score	0.053675 (rank : 412)	θ value	5.27518 (rank : 345)
Query Neighborhood Hits	382	Target Neighborhood Hits	939	Shared Neighborhood Hits	119
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CEP63_HUMAN
NC score	0.053619 (rank : 413)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	382	Target Neighborhood Hits	1005	Shared Neighborhood Hits	126
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

ERC2_HUMAN
NC score	0.053573 (rank : 414)	θ value	0.0252991 (rank : 169)
Query Neighborhood Hits	382	Target Neighborhood Hits	1156	Shared Neighborhood Hits	118
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MY18A_MOUSE
NC score	0.053363 (rank : 415)	θ value	2.36792 (rank : 309)
Query Neighborhood Hits	382	Target Neighborhood Hits	1989	Shared Neighborhood Hits	158
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PCNT_MOUSE
NC score	0.053256 (rank : 416)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	382	Target Neighborhood Hits	1207	Shared Neighborhood Hits	141
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CT096_HUMAN
NC score	0.053097 (rank : 417)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	382	Target Neighborhood Hits	438	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CEP55_MOUSE
NC score	0.053030 (rank : 418)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	382	Target Neighborhood Hits	693	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

KTN1_MOUSE
NC score	0.052988 (rank : 419)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	382	Target Neighborhood Hits	1324	Shared Neighborhood Hits	148
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

RBCC1_MOUSE
NC score	0.052968 (rank : 420)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	382	Target Neighborhood Hits	1048	Shared Neighborhood Hits	125
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CCD27_HUMAN
NC score	0.052951 (rank : 421)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	382	Target Neighborhood Hits	594	Shared Neighborhood Hits	85
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

ERC2_MOUSE
NC score	0.052811 (rank : 422)	θ value	0.0252991 (rank : 170)
Query Neighborhood Hits	382	Target Neighborhood Hits	1166	Shared Neighborhood Hits	116
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

SKIL_HUMAN
NC score	0.052410 (rank : 423)	θ value	0.0330416 (rank : 182)
Query Neighborhood Hits	382	Target Neighborhood Hits	460	Shared Neighborhood Hits	65
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CN145_HUMAN
NC score	0.052404 (rank : 424)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	382	Target Neighborhood Hits	1196	Shared Neighborhood Hits	133
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

EEA1_MOUSE
NC score	0.052391 (rank : 425)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	382	Target Neighborhood Hits	1637	Shared Neighborhood Hits	149
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CNTRB_MOUSE
NC score	0.052060 (rank : 426)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	382	Target Neighborhood Hits	1029	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

RUFY2_HUMAN
NC score	0.052008 (rank : 427)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	382	Target Neighborhood Hits	1208	Shared Neighborhood Hits	120
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

OPTN_MOUSE
NC score	0.051982 (rank : 428)	θ value	0.163984 (rank : 220)
Query Neighborhood Hits	382	Target Neighborhood Hits	1120	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

GRAP1_MOUSE
NC score	0.051746 (rank : 429)	θ value	8.99809 (rank : 372)
Query Neighborhood Hits	382	Target Neighborhood Hits	1234	Shared Neighborhood Hits	139
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

RNF17_MOUSE
NC score	0.051495 (rank : 430)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	382	Target Neighborhood Hits	147	Shared Neighborhood Hits	39
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

MYH11_HUMAN
NC score	0.051395 (rank : 431)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	382	Target Neighborhood Hits	1806	Shared Neighborhood Hits	163
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

IFT74_HUMAN
NC score	0.051204 (rank : 432)	θ value	0.47712 (rank : 250)
Query Neighborhood Hits	382	Target Neighborhood Hits	949	Shared Neighborhood Hits	117
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

GOGA1_HUMAN
NC score	0.051180 (rank : 433)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	382	Target Neighborhood Hits	1222	Shared Neighborhood Hits	130
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CASP_MOUSE
NC score	0.050926 (rank : 434)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	382	Target Neighborhood Hits	1152	Shared Neighborhood Hits	127
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

BPAEA_MOUSE
NC score	0.050737 (rank : 435)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	382	Target Neighborhood Hits	1480	Shared Neighborhood Hits	144
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CT2NL_MOUSE
NC score	0.050651 (rank : 436)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	382	Target Neighborhood Hits	902	Shared Neighborhood Hits	113
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ZN363_MOUSE
NC score	0.050547 (rank : 437)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	382	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

MYH11_MOUSE
NC score	0.050536 (rank : 438)	θ value	0.813845 (rank : 262)
Query Neighborhood Hits	382	Target Neighborhood Hits	1777	Shared Neighborhood Hits	158
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SKIL_MOUSE
NC score	0.050423 (rank : 439)	θ value	0.0961366 (rank : 204)
Query Neighborhood Hits	382	Target Neighborhood Hits	719	Shared Neighborhood Hits	86
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CING_HUMAN
NC score	0.050237 (rank : 440)	θ value	1.38821 (rank : 280)
Query Neighborhood Hits	382	Target Neighborhood Hits	1275	Shared Neighborhood Hits	124
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

T3JAM_HUMAN
NC score	0.050013 (rank : 441)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	382	Target Neighborhood Hits	533	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

NAF1_MOUSE
NC score	0.048470 (rank : 442)	θ value	8.99809 (rank : 378)
Query Neighborhood Hits	382	Target Neighborhood Hits	852	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PLEC1_HUMAN
NC score	0.046892 (rank : 443)	θ value	0.125558 (rank : 208)
Query Neighborhood Hits	382	Target Neighborhood Hits	1326	Shared Neighborhood Hits	129
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

CALD1_HUMAN
NC score	0.046223 (rank : 444)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	382	Target Neighborhood Hits	959	Shared Neighborhood Hits	100
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MYH9_MOUSE
NC score	0.045585 (rank : 445)	θ value	8.99809 (rank : 377)
Query Neighborhood Hits	382	Target Neighborhood Hits	1829	Shared Neighborhood Hits	160
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

UACA_MOUSE
NC score	0.044574 (rank : 446)	θ value	2.36792 (rank : 313)
Query Neighborhood Hits	382	Target Neighborhood Hits	1620	Shared Neighborhood Hits	138
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

BICD2_MOUSE
NC score	0.044415 (rank : 447)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	382	Target Neighborhood Hits	864	Shared Neighborhood Hits	115
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_HUMAN
NC score	0.044257 (rank : 448)	θ value	4.03905 (rank : 328)
Query Neighborhood Hits	382	Target Neighborhood Hits	856	Shared Neighborhood Hits	115
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

MYH14_MOUSE
NC score	0.041940 (rank : 449)	θ value	8.99809 (rank : 376)
Query Neighborhood Hits	382	Target Neighborhood Hits	1225	Shared Neighborhood Hits	130
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TPM3_MOUSE
NC score	0.041179 (rank : 450)	θ value	6.88961 (rank : 366)
Query Neighborhood Hits	382	Target Neighborhood Hits	676	Shared Neighborhood Hits	92
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

RILP_HUMAN
NC score	0.041161 (rank : 451)	θ value	0.365318 (rank : 244)
Query Neighborhood Hits	382	Target Neighborhood Hits	249	Shared Neighborhood Hits	41
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

CKAP4_MOUSE
NC score	0.040954 (rank : 452)	θ value	5.27518 (rank : 340)
Query Neighborhood Hits	382	Target Neighborhood Hits	596	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

SPFH2_HUMAN
NC score	0.040368 (rank : 453)	θ value	0.0961366 (rank : 205)
Query Neighborhood Hits	382	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O94905, Q6NW21, Q86VS6, Q86W49	Gene names	SPFH2, C8orf2
Domain Architecture
Description	SPFH domain-containing protein 2 precursor.

RABE2_MOUSE
NC score	0.039577 (rank : 454)	θ value	6.88961 (rank : 363)
Query Neighborhood Hits	382	Target Neighborhood Hits	598	Shared Neighborhood Hits	95
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SPFH2_MOUSE
NC score	0.039441 (rank : 455)	θ value	0.125558 (rank : 211)
Query Neighborhood Hits	382	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BFZ9, Q8BML8	Gene names	Spfh2
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 2 precursor.

ARI1_HUMAN
NC score	0.038635 (rank : 456)	θ value	4.03905 (rank : 326)
Query Neighborhood Hits	382	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.038622 (rank : 457)	θ value	4.03905 (rank : 327)
Query Neighborhood Hits	382	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

MYO5C_HUMAN
NC score	0.038364 (rank : 458)	θ value	0.47712 (rank : 251)
Query Neighborhood Hits	382	Target Neighborhood Hits	1206	Shared Neighborhood Hits	135
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

KMHN1_HUMAN
NC score	0.037971 (rank : 459)	θ value	6.88961 (rank : 360)
Query Neighborhood Hits	382	Target Neighborhood Hits	950	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

CKAP4_HUMAN
NC score	0.037730 (rank : 460)	θ value	8.99809 (rank : 371)
Query Neighborhood Hits	382	Target Neighborhood Hits	592	Shared Neighborhood Hits	83
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MAP1A_HUMAN
NC score	0.035408 (rank : 461)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	382	Target Neighborhood Hits	1626	Shared Neighborhood Hits	114
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ITSN2_MOUSE
NC score	0.034828 (rank : 462)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	382	Target Neighborhood Hits	1371	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ASPP2_HUMAN
NC score	0.033988 (rank : 463)	θ value	0.21417 (rank : 225)
Query Neighborhood Hits	382	Target Neighborhood Hits	1156	Shared Neighborhood Hits	94
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

U2AFM_MOUSE
NC score	0.033017 (rank : 464)	θ value	0.365318 (rank : 247)
Query Neighborhood Hits	382	Target Neighborhood Hits	543	Shared Neighborhood Hits	71
SwissProt Accessions	Q62377	Gene names	Zrsr2, U2af1-rs2, U2af1l2, U2af1rs2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2).

SPFH1_HUMAN
NC score	0.032359 (rank : 465)	θ value	1.81305 (rank : 298)
Query Neighborhood Hits	382	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

ITSN1_MOUSE
NC score	0.032158 (rank : 466)	θ value	6.88961 (rank : 359)
Query Neighborhood Hits	382	Target Neighborhood Hits	1669	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

LZTS1_MOUSE
NC score	0.031946 (rank : 467)	θ value	8.99809 (rank : 374)
Query Neighborhood Hits	382	Target Neighborhood Hits	540	Shared Neighborhood Hits	87
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

SNX23_HUMAN
NC score	0.031558 (rank : 468)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	382	Target Neighborhood Hits	944	Shared Neighborhood Hits	109
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ITSN1_HUMAN
NC score	0.031339 (rank : 469)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	382	Target Neighborhood Hits	1757	Shared Neighborhood Hits	120
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KIF5C_MOUSE
NC score	0.030861 (rank : 470)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	382	Target Neighborhood Hits	1040	Shared Neighborhood Hits	113
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

CF182_MOUSE
NC score	0.030828 (rank : 471)	θ value	5.27518 (rank : 339)
Query Neighborhood Hits	382	Target Neighborhood Hits	551	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

JIP4_HUMAN
NC score	0.030230 (rank : 472)	θ value	1.81305 (rank : 296)
Query Neighborhood Hits	382	Target Neighborhood Hits	585	Shared Neighborhood Hits	80
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

KIF5C_HUMAN
NC score	0.030193 (rank : 473)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	382	Target Neighborhood Hits	974	Shared Neighborhood Hits	111
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

DYHC_HUMAN
NC score	0.029657 (rank : 474)	θ value	2.36792 (rank : 303)
Query Neighborhood Hits	382	Target Neighborhood Hits	733	Shared Neighborhood Hits	98
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.029555 (rank : 475)	θ value	2.36792 (rank : 304)
Query Neighborhood Hits	382	Target Neighborhood Hits	729	Shared Neighborhood Hits	97
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

CCD22_HUMAN
NC score	0.027809 (rank : 476)	θ value	1.06291 (rank : 265)
Query Neighborhood Hits	382	Target Neighborhood Hits	242	Shared Neighborhood Hits	45
SwissProt Accessions	O60826	Gene names	CCDC22, CXorf37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 22.

PDCD7_MOUSE
NC score	0.027520 (rank : 477)	θ value	8.99809 (rank : 379)
Query Neighborhood Hits	382	Target Neighborhood Hits	214	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTY1, Q8R5D9	Gene names	Pdcd7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18).

ASPP1_HUMAN
NC score	0.027406 (rank : 478)	θ value	1.81305 (rank : 291)
Query Neighborhood Hits	382	Target Neighborhood Hits	956	Shared Neighborhood Hits	78
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PDCD7_HUMAN
NC score	0.027246 (rank : 479)	θ value	1.06291 (rank : 271)
Query Neighborhood Hits	382	Target Neighborhood Hits	255	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8D1, Q96AK8, Q9Y6D7	Gene names	PDCD7
Domain Architecture	No domain graphic available
Description	Programmed cell death protein 7 (ES18) (HES18).

TARA_HUMAN
NC score	0.027223 (rank : 480)	θ value	1.06291 (rank : 273)
Query Neighborhood Hits	382	Target Neighborhood Hits	1626	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SFR17_HUMAN
NC score	0.026719 (rank : 481)	θ value	1.38821 (rank : 290)
Query Neighborhood Hits	382	Target Neighborhood Hits	325	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

DREB_HUMAN
NC score	0.026362 (rank : 482)	θ value	5.27518 (rank : 342)
Query Neighborhood Hits	382	Target Neighborhood Hits	450	Shared Neighborhood Hits	60
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

MVP_MOUSE
NC score	0.025691 (rank : 483)	θ value	1.38821 (rank : 287)
Query Neighborhood Hits	382	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQK5	Gene names	Mvp
Domain Architecture
Description	Major vault protein (MVP).

ITSN2_HUMAN
NC score	0.025674 (rank : 484)	θ value	8.99809 (rank : 373)
Query Neighborhood Hits	382	Target Neighborhood Hits	1173	Shared Neighborhood Hits	101
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ASPP1_MOUSE
NC score	0.024856 (rank : 485)	θ value	2.36792 (rank : 302)
Query Neighborhood Hits	382	Target Neighborhood Hits	1244	Shared Neighborhood Hits	85
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MVP_HUMAN
NC score	0.023719 (rank : 486)	θ value	1.81305 (rank : 297)
Query Neighborhood Hits	382	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q14764, Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1	Gene names	MVP, LRP
Domain Architecture
Description	Major vault protein (MVP) (Lung resistance-related protein).

GCP6_HUMAN
NC score	0.022129 (rank : 487)	θ value	1.38821 (rank : 284)
Query Neighborhood Hits	382	Target Neighborhood Hits	295	Shared Neighborhood Hits	43
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

ROCK1_MOUSE
NC score	0.021911 (rank : 488)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	382	Target Neighborhood Hits	2126	Shared Neighborhood Hits	146
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CTRO_MOUSE
NC score	0.020439 (rank : 489)	θ value	1.38821 (rank : 283)
Query Neighborhood Hits	382	Target Neighborhood Hits	2344	Shared Neighborhood Hits	149
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CCD70_MOUSE
NC score	0.020432 (rank : 490)	θ value	1.38821 (rank : 278)
Query Neighborhood Hits	382	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D9B0, Q9D9H6	Gene names	Ccdc70
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 70 precursor.

CTRO_HUMAN
NC score	0.017057 (rank : 491)	θ value	1.38821 (rank : 282)
Query Neighborhood Hits	382	Target Neighborhood Hits	2092	Shared Neighborhood Hits	134
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SPSB2_MOUSE
NC score	0.014846 (rank : 492)	θ value	1.81305 (rank : 299)
Query Neighborhood Hits	382	Target Neighborhood Hits	38	Shared Neighborhood Hits	7
SwissProt Accessions	O88838, Q8CBA5, Q91Z15	Gene names	Spsb2, Grcc9, Ssb2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

CD016_HUMAN
NC score	0.014756 (rank : 493)	θ value	8.99809 (rank : 369)
Query Neighborhood Hits	382	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

CCD70_HUMAN
NC score	0.014037 (rank : 494)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	382	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NSX1, Q8N7A8, Q9H097	Gene names	CCDC70
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 70 precursor.

KIF3C_MOUSE
NC score	0.014030 (rank : 495)	θ value	5.27518 (rank : 346)
Query Neighborhood Hits	382	Target Neighborhood Hits	468	Shared Neighborhood Hits	69
SwissProt Accessions	O35066, O35229	Gene names	Kif3c
Domain Architecture
Description	Kinesin-like protein KIF3C.

PEX5_HUMAN
NC score	0.013744 (rank : 496)	θ value	0.365318 (rank : 242)
Query Neighborhood Hits	382	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

KIF3C_HUMAN
NC score	0.013456 (rank : 497)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	382	Target Neighborhood Hits	478	Shared Neighborhood Hits	71
SwissProt Accessions	O14782, O43544	Gene names	KIF3C
Domain Architecture
Description	Kinesin-like protein KIF3C.

SPSB2_HUMAN
NC score	0.012443 (rank : 498)	θ value	6.88961 (rank : 364)
Query Neighborhood Hits	382	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q99619	Gene names	SPSB2, GRCC9, SSB2
Domain Architecture	No domain graphic available
Description	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9).

SH3G1_HUMAN
NC score	0.011680 (rank : 499)	θ value	1.06291 (rank : 272)
Query Neighborhood Hits	382	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

PHF1_MOUSE
NC score	0.010975 (rank : 500)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	382	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

SMCA2_HUMAN
NC score	0.010215 (rank : 501)	θ value	2.36792 (rank : 312)
Query Neighborhood Hits	382	Target Neighborhood Hits	503	Shared Neighborhood Hits	45
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

MINK1_HUMAN
NC score	0.001636 (rank : 502)	θ value	8.99809 (rank : 375)
Query Neighborhood Hits	382	Target Neighborhood Hits	1477	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

CD2L1_HUMAN
NC score	-0.000716 (rank : 503)	θ value	1.06291 (rank : 267)
Query Neighborhood Hits	382	Target Neighborhood Hits	1467	Shared Neighborhood Hits	76
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD2L1_MOUSE
NC score	-0.000959 (rank : 504)	θ value	0.62314 (rank : 257)
Query Neighborhood Hits	382	Target Neighborhood Hits	1463	Shared Neighborhood Hits	76
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

CD2L2_HUMAN
NC score	-0.002269 (rank : 505)	θ value	1.81305 (rank : 292)
Query Neighborhood Hits	382	Target Neighborhood Hits	1439	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

TAOK2_MOUSE
NC score	-0.002719 (rank : 506)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	382	Target Neighborhood Hits	1373	Shared Neighborhood Hits	81
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

GUC2F_HUMAN
NC score	-0.004616 (rank : 507)	θ value	0.47712 (rank : 248)
Query Neighborhood Hits	382	Target Neighborhood Hits	740	Shared Neighborhood Hits	12
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

E2AK4_HUMAN
NC score	-0.005165 (rank : 508)	θ value	5.27518 (rank : 343)
Query Neighborhood Hits	382	Target Neighborhood Hits	1012	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

E2AK4_MOUSE
NC score	-0.006248 (rank : 509)	θ value	5.27518 (rank : 344)
Query Neighborhood Hits	382	Target Neighborhood Hits	984	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

TCF8_HUMAN
NC score	-0.007554 (rank : 510)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	382	Target Neighborhood Hits	1057	Shared Neighborhood Hits	41
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

HIC1_MOUSE
NC score	-0.008438 (rank : 511)	θ value	1.06291 (rank : 269)
Query Neighborhood Hits	382	Target Neighborhood Hits	863	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1Y5, Q9R1Y6, Q9R2B0	Gene names	Hic1
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1).

HIC1_HUMAN
NC score	-0.008503 (rank : 512)	θ value	1.06291 (rank : 268)
Query Neighborhood Hits	382	Target Neighborhood Hits	838	Shared Neighborhood Hits	8
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HIC2_HUMAN
NC score	-0.008947 (rank : 513)	θ value	2.36792 (rank : 306)
Query Neighborhood Hits	382	Target Neighborhood Hits	820	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

HIC2_MOUSE
NC score	-0.009335 (rank : 514)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	382	Target Neighborhood Hits	821	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JLZ6, Q3U030, Q3ULP4, Q5K036, Q8BSZ9, Q8C3T5	Gene names	Hic2, Kiaa1020
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2).