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Network neighborhood for query Sequence : MEFV_HUMAN

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MEFV_HUMAN
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEFV_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	431	Target Neighborhood Hits	431	Shared Neighborhood Hits	431
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	8.35901e-139 (rank : 2)	NC score	0.774427 (rank : 60)
Query Neighborhood Hits	431	Target Neighborhood Hits	236	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI27_HUMAN
θ value	3.00772e-96 (rank : 3)	NC score	0.932221 (rank : 3)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	4.34313e-95 (rank : 4)	NC score	0.932855 (rank : 2)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	125
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI39_HUMAN
θ value	1.5555e-68 (rank : 5)	NC score	0.892336 (rank : 20)
Query Neighborhood Hits	431	Target Neighborhood Hits	693	Shared Neighborhood Hits	208
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	2.93355e-67 (rank : 6)	NC score	0.894285 (rank : 19)
Query Neighborhood Hits	431	Target Neighborhood Hits	691	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

RO52_HUMAN
θ value	5.00389e-67 (rank : 7)	NC score	0.903569 (rank : 15)
Query Neighborhood Hits	431	Target Neighborhood Hits	419	Shared Neighborhood Hits	152
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI68_HUMAN
θ value	2.65945e-60 (rank : 8)	NC score	0.916563 (rank : 4)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	120
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
θ value	2.25136e-59 (rank : 9)	NC score	0.913268 (rank : 5)
Query Neighborhood Hits	431	Target Neighborhood Hits	356	Shared Neighborhood Hits	144
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI11_HUMAN
θ value	1.61343e-57 (rank : 10)	NC score	0.909791 (rank : 9)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	131
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

ERMAP_HUMAN
θ value	3.974e-56 (rank : 11)	NC score	0.888785 (rank : 22)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI11_MOUSE
θ value	1.97229e-55 (rank : 12)	NC score	0.910800 (rank : 7)
Query Neighborhood Hits	431	Target Neighborhood Hits	329	Shared Neighborhood Hits	134
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

RO52_MOUSE
θ value	5.73848e-55 (rank : 13)	NC score	0.904686 (rank : 14)
Query Neighborhood Hits	431	Target Neighborhood Hits	360	Shared Neighborhood Hits	135
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRIM7_MOUSE
θ value	9.78833e-55 (rank : 14)	NC score	0.906000 (rank : 13)
Query Neighborhood Hits	431	Target Neighborhood Hits	358	Shared Neighborhood Hits	153
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

ERMAP_MOUSE
θ value	2.18062e-54 (rank : 15)	NC score	0.858788 (rank : 37)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRIM7_HUMAN
θ value	5.93839e-52 (rank : 16)	NC score	0.908692 (rank : 10)
Query Neighborhood Hits	431	Target Neighborhood Hits	336	Shared Neighborhood Hits	146
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM6_MOUSE
θ value	2.49495e-50 (rank : 17)	NC score	0.883742 (rank : 28)
Query Neighborhood Hits	431	Target Neighborhood Hits	451	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRI38_HUMAN
θ value	3.2585e-50 (rank : 18)	NC score	0.911118 (rank : 6)
Query Neighborhood Hits	431	Target Neighborhood Hits	373	Shared Neighborhood Hits	154
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI15_HUMAN
θ value	4.70527e-49 (rank : 19)	NC score	0.906162 (rank : 12)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI60_HUMAN
θ value	1.04822e-48 (rank : 20)	NC score	0.898061 (rank : 17)
Query Neighborhood Hits	431	Target Neighborhood Hits	357	Shared Neighborhood Hits	143
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM6_HUMAN
θ value	1.04822e-48 (rank : 21)	NC score	0.885550 (rank : 25)
Query Neighborhood Hits	431	Target Neighborhood Hits	412	Shared Neighborhood Hits	158
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI10_HUMAN
θ value	2.85459e-46 (rank : 22)	NC score	0.892245 (rank : 21)
Query Neighborhood Hits	431	Target Neighborhood Hits	315	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI17_MOUSE
θ value	6.35935e-46 (rank : 23)	NC score	0.885197 (rank : 26)
Query Neighborhood Hits	431	Target Neighborhood Hits	620	Shared Neighborhood Hits	199
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI10_MOUSE
θ value	8.30557e-46 (rank : 24)	NC score	0.894396 (rank : 18)
Query Neighborhood Hits	431	Target Neighborhood Hits	285	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

BT1A1_HUMAN
θ value	1.73182e-43 (rank : 25)	NC score	0.811350 (rank : 58)
Query Neighborhood Hits	431	Target Neighborhood Hits	322	Shared Neighborhood Hits	82
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

TRI17_HUMAN
θ value	2.95404e-43 (rank : 26)	NC score	0.900415 (rank : 16)
Query Neighborhood Hits	431	Target Neighborhood Hits	318	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI34_HUMAN
θ value	1.91475e-42 (rank : 27)	NC score	0.867302 (rank : 35)
Query Neighborhood Hits	431	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	3.26607e-42 (rank : 28)	NC score	0.884379 (rank : 27)
Query Neighborhood Hits	431	Target Neighborhood Hits	332	Shared Neighborhood Hits	146
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

BT1A1_MOUSE
θ value	7.27602e-42 (rank : 29)	NC score	0.820287 (rank : 54)
Query Neighborhood Hits	431	Target Neighborhood Hits	252	Shared Neighborhood Hits	82
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A2_HUMAN
θ value	7.27602e-42 (rank : 30)	NC score	0.835345 (rank : 45)
Query Neighborhood Hits	431	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT3A3_HUMAN
θ value	2.11701e-41 (rank : 31)	NC score	0.819952 (rank : 55)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	81
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT3A1_HUMAN
θ value	1.79215e-40 (rank : 32)	NC score	0.818887 (rank : 56)
Query Neighborhood Hits	431	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI41_HUMAN
θ value	3.99248e-40 (rank : 33)	NC score	0.910484 (rank : 8)
Query Neighborhood Hits	431	Target Neighborhood Hits	349	Shared Neighborhood Hits	156
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRIM5_HUMAN
θ value	8.89434e-40 (rank : 34)	NC score	0.867459 (rank : 34)
Query Neighborhood Hits	431	Target Neighborhood Hits	424	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI22_HUMAN
θ value	5.76516e-39 (rank : 35)	NC score	0.853781 (rank : 39)
Query Neighborhood Hits	431	Target Neighborhood Hits	396	Shared Neighborhood Hits	145
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI60_MOUSE
θ value	2.19075e-38 (rank : 36)	NC score	0.907422 (rank : 11)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

BT2A1_HUMAN
θ value	1.08726e-37 (rank : 37)	NC score	0.824880 (rank : 50)
Query Neighborhood Hits	431	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

RFPL1_HUMAN
θ value	3.4976e-36 (rank : 38)	NC score	0.887313 (rank : 24)
Query Neighborhood Hits	431	Target Neighborhood Hits	119	Shared Neighborhood Hits	90
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI62_MOUSE
θ value	3.4976e-36 (rank : 39)	NC score	0.872968 (rank : 31)
Query Neighborhood Hits	431	Target Neighborhood Hits	478	Shared Neighborhood Hits	169
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

BTNL9_HUMAN
θ value	5.96599e-36 (rank : 40)	NC score	0.833710 (rank : 46)
Query Neighborhood Hits	431	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

TRI62_HUMAN
θ value	5.96599e-36 (rank : 41)	NC score	0.869396 (rank : 33)
Query Neighborhood Hits	431	Target Neighborhood Hits	584	Shared Neighborhood Hits	191
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

RFPL3_HUMAN
θ value	1.01765e-35 (rank : 42)	NC score	0.887945 (rank : 23)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	92
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

BT2A3_HUMAN
θ value	3.86705e-35 (rank : 43)	NC score	0.822112 (rank : 53)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	77
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

RFPL2_HUMAN
θ value	8.61488e-35 (rank : 44)	NC score	0.882307 (rank : 29)
Query Neighborhood Hits	431	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRI50_MOUSE
θ value	5.584e-34 (rank : 45)	NC score	0.853896 (rank : 38)
Query Neighborhood Hits	431	Target Neighborhood Hits	326	Shared Neighborhood Hits	132
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

BTNL3_HUMAN
θ value	9.52487e-34 (rank : 46)	NC score	0.823639 (rank : 51)
Query Neighborhood Hits	431	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI26_HUMAN
θ value	1.6247e-33 (rank : 47)	NC score	0.842002 (rank : 42)
Query Neighborhood Hits	431	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI50_HUMAN
θ value	2.77131e-33 (rank : 48)	NC score	0.848046 (rank : 40)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	125
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI26_MOUSE
θ value	1.79631e-32 (rank : 49)	NC score	0.838676 (rank : 44)
Query Neighborhood Hits	431	Target Neighborhood Hits	339	Shared Neighborhood Hits	123
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI43_HUMAN
θ value	1.98606e-31 (rank : 50)	NC score	0.865544 (rank : 36)
Query Neighborhood Hits	431	Target Neighborhood Hits	341	Shared Neighborhood Hits	141
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI49_HUMAN
θ value	3.3877e-31 (rank : 51)	NC score	0.872951 (rank : 32)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRIM4_HUMAN
θ value	3.17079e-29 (rank : 52)	NC score	0.877764 (rank : 30)
Query Neighborhood Hits	431	Target Neighborhood Hits	321	Shared Neighborhood Hits	137
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

BTNL8_HUMAN
θ value	5.40856e-29 (rank : 53)	NC score	0.803184 (rank : 59)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

TRI30_MOUSE
θ value	2.05525e-28 (rank : 54)	NC score	0.831456 (rank : 48)
Query Neighborhood Hits	431	Target Neighborhood Hits	434	Shared Neighborhood Hits	164
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI35_HUMAN
θ value	1.80048e-24 (rank : 55)	NC score	0.840716 (rank : 43)
Query Neighborhood Hits	431	Target Neighborhood Hits	382	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	2.69047e-20 (rank : 56)	NC score	0.829234 (rank : 49)
Query Neighborhood Hits	431	Target Neighborhood Hits	465	Shared Neighborhood Hits	172
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI14_MOUSE
θ value	3.51386e-20 (rank : 57)	NC score	0.822753 (rank : 52)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
θ value	5.07402e-19 (rank : 58)	NC score	0.813484 (rank : 57)
Query Neighborhood Hits	431	Target Neighborhood Hits	143	Shared Neighborhood Hits	117
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI31_HUMAN
θ value	1.92812e-18 (rank : 59)	NC score	0.742271 (rank : 63)
Query Neighborhood Hits	431	Target Neighborhood Hits	299	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

BSPRY_HUMAN
θ value	5.25075e-16 (rank : 60)	NC score	0.772481 (rank : 61)
Query Neighborhood Hits	431	Target Neighborhood Hits	115	Shared Neighborhood Hits	100
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI48_HUMAN
θ value	1.68911e-14 (rank : 61)	NC score	0.833459 (rank : 47)
Query Neighborhood Hits	431	Target Neighborhood Hits	192	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

RNF39_HUMAN
θ value	2.20605e-14 (rank : 62)	NC score	0.847603 (rank : 41)
Query Neighborhood Hits	431	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI16_HUMAN
θ value	4.16044e-13 (rank : 63)	NC score	0.686361 (rank : 68)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	128
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

BSPRY_MOUSE
θ value	3.29651e-10 (rank : 64)	NC score	0.758629 (rank : 62)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	101
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI12_MOUSE
θ value	3.29651e-10 (rank : 65)	NC score	0.734363 (rank : 64)
Query Neighborhood Hits	431	Target Neighborhood Hits	387	Shared Neighborhood Hits	132
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI16_MOUSE
θ value	4.30538e-10 (rank : 66)	NC score	0.683627 (rank : 70)
Query Neighborhood Hits	431	Target Neighborhood Hits	196	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI18_HUMAN
θ value	2.13673e-09 (rank : 67)	NC score	0.588332 (rank : 79)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI25_HUMAN
θ value	3.64472e-09 (rank : 68)	NC score	0.656265 (rank : 75)
Query Neighborhood Hits	431	Target Neighborhood Hits	472	Shared Neighborhood Hits	169
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	4.76016e-09 (rank : 69)	NC score	0.642985 (rank : 76)
Query Neighborhood Hits	431	Target Neighborhood Hits	446	Shared Neighborhood Hits	162
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

ASC_MOUSE
θ value	2.36244e-08 (rank : 70)	NC score	0.161223 (rank : 188)
Query Neighborhood Hits	431	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

NAL10_HUMAN
θ value	3.08544e-08 (rank : 71)	NC score	0.123837 (rank : 218)
Query Neighborhood Hits	431	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

SPRY4_MOUSE
θ value	2.61198e-07 (rank : 72)	NC score	0.714217 (rank : 66)
Query Neighborhood Hits	431	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI18_MOUSE
θ value	4.45536e-07 (rank : 73)	NC score	0.565248 (rank : 82)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	130
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

SPRY4_HUMAN
θ value	5.81887e-07 (rank : 74)	NC score	0.697450 (rank : 67)
Query Neighborhood Hits	431	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

CIAS1_HUMAN
θ value	9.92553e-07 (rank : 75)	NC score	0.104522 (rank : 238)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

TRI65_MOUSE
θ value	1.29631e-06 (rank : 76)	NC score	0.675347 (rank : 71)
Query Neighborhood Hits	431	Target Neighborhood Hits	340	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ASC_HUMAN
θ value	2.21117e-06 (rank : 77)	NC score	0.145707 (rank : 199)
Query Neighborhood Hits	431	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

TRI40_HUMAN
θ value	2.21117e-06 (rank : 78)	NC score	0.684575 (rank : 69)
Query Neighborhood Hits	431	Target Neighborhood Hits	279	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI59_MOUSE
θ value	2.21117e-06 (rank : 79)	NC score	0.585340 (rank : 80)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	117
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

CIAS1_MOUSE
θ value	4.92598e-06 (rank : 80)	NC score	0.105037 (rank : 236)
Query Neighborhood Hits	431	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

TRI59_HUMAN
θ value	6.43352e-06 (rank : 81)	NC score	0.582951 (rank : 81)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRIM1_HUMAN
θ value	6.43352e-06 (rank : 82)	NC score	0.544410 (rank : 86)
Query Neighborhood Hits	431	Target Neighborhood Hits	345	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	6.43352e-06 (rank : 83)	NC score	0.542714 (rank : 87)
Query Neighborhood Hits	431	Target Neighborhood Hits	361	Shared Neighborhood Hits	149
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

NAL12_HUMAN
θ value	1.09739e-05 (rank : 84)	NC score	0.101264 (rank : 245)
Query Neighborhood Hits	431	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP4_HUMAN
θ value	1.09739e-05 (rank : 85)	NC score	0.097431 (rank : 248)
Query Neighborhood Hits	431	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

TRI73_HUMAN
θ value	3.19293e-05 (rank : 86)	NC score	0.671701 (rank : 74)
Query Neighborhood Hits	431	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	3.19293e-05 (rank : 87)	NC score	0.672480 (rank : 73)
Query Neighborhood Hits	431	Target Neighborhood Hits	249	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI52_HUMAN
θ value	4.1701e-05 (rank : 88)	NC score	0.721807 (rank : 65)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

NAL14_HUMAN
θ value	9.29e-05 (rank : 89)	NC score	0.086618 (rank : 261)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

TRI13_MOUSE
θ value	0.00035302 (rank : 90)	NC score	0.608160 (rank : 77)
Query Neighborhood Hits	431	Target Neighborhood Hits	282	Shared Neighborhood Hits	114
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI36_HUMAN
θ value	0.000461057 (rank : 91)	NC score	0.384670 (rank : 110)
Query Neighborhood Hits	431	Target Neighborhood Hits	282	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

NALP6_HUMAN
θ value	0.000602161 (rank : 92)	NC score	0.100567 (rank : 246)
Query Neighborhood Hits	431	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

MECP2_MOUSE
θ value	0.000786445 (rank : 93)	NC score	0.057026 (rank : 368)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

TRI47_MOUSE
θ value	0.000786445 (rank : 94)	NC score	0.556526 (rank : 83)
Query Neighborhood Hits	431	Target Neighborhood Hits	295	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI65_HUMAN
θ value	0.000786445 (rank : 95)	NC score	0.673258 (rank : 72)
Query Neighborhood Hits	431	Target Neighborhood Hits	330	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI13_HUMAN
θ value	0.00102713 (rank : 96)	NC score	0.605819 (rank : 78)
Query Neighborhood Hits	431	Target Neighborhood Hits	274	Shared Neighborhood Hits	109
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI36_MOUSE
θ value	0.00102713 (rank : 97)	NC score	0.376502 (rank : 113)
Query Neighborhood Hits	431	Target Neighborhood Hits	266	Shared Neighborhood Hits	135
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRIM9_MOUSE
θ value	0.00102713 (rank : 98)	NC score	0.378677 (rank : 112)
Query Neighborhood Hits	431	Target Neighborhood Hits	274	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

MECP2_HUMAN
θ value	0.00134147 (rank : 99)	NC score	0.056141 (rank : 384)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	14
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

NAL10_MOUSE
θ value	0.00134147 (rank : 100)	NC score	0.104633 (rank : 237)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

TRI29_HUMAN
θ value	0.00134147 (rank : 101)	NC score	0.458688 (rank : 102)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	127
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRIM8_HUMAN
θ value	0.00134147 (rank : 102)	NC score	0.551081 (rank : 85)
Query Neighborhood Hits	431	Target Neighborhood Hits	650	Shared Neighborhood Hits	190
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	0.00175202 (rank : 103)	NC score	0.553314 (rank : 84)
Query Neighborhood Hits	431	Target Neighborhood Hits	674	Shared Neighborhood Hits	189
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM9_HUMAN
θ value	0.00175202 (rank : 104)	NC score	0.387461 (rank : 109)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI29_MOUSE
θ value	0.00228821 (rank : 105)	NC score	0.471697 (rank : 99)
Query Neighborhood Hits	431	Target Neighborhood Hits	306	Shared Neighborhood Hits	135
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TIF1B_HUMAN
θ value	0.00298849 (rank : 106)	NC score	0.204511 (rank : 168)
Query Neighborhood Hits	431	Target Neighborhood Hits	312	Shared Neighborhood Hits	105
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRI37_HUMAN
θ value	0.00298849 (rank : 107)	NC score	0.479631 (rank : 98)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	116
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	0.00298849 (rank : 108)	NC score	0.479803 (rank : 97)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	119
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

NALP2_HUMAN
θ value	0.00390308 (rank : 109)	NC score	0.086446 (rank : 262)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

EGLN1_HUMAN
θ value	0.00665767 (rank : 110)	NC score	0.023272 (rank : 535)
Query Neighborhood Hits	431	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

HXA4_MOUSE
θ value	0.00665767 (rank : 111)	NC score	0.004846 (rank : 648)
Query Neighborhood Hits	431	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

SRRM2_HUMAN
θ value	0.00665767 (rank : 112)	NC score	0.037820 (rank : 490)
Query Neighborhood Hits	431	Target Neighborhood Hits	1296	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TRIM3_MOUSE
θ value	0.00869519 (rank : 113)	NC score	0.446974 (rank : 103)
Query Neighborhood Hits	431	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

NFH_HUMAN
θ value	0.0113563 (rank : 114)	NC score	0.023906 (rank : 533)
Query Neighborhood Hits	431	Target Neighborhood Hits	1242	Shared Neighborhood Hits	132
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TIF1B_MOUSE
θ value	0.0113563 (rank : 115)	NC score	0.197874 (rank : 172)
Query Neighborhood Hits	431	Target Neighborhood Hits	276	Shared Neighborhood Hits	96
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

NALP5_HUMAN
θ value	0.0148317 (rank : 116)	NC score	0.085553 (rank : 264)
Query Neighborhood Hits	431	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NCOR2_HUMAN
θ value	0.0148317 (rank : 117)	NC score	0.030180 (rank : 516)
Query Neighborhood Hits	431	Target Neighborhood Hits	870	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TRI32_MOUSE
θ value	0.0148317 (rank : 118)	NC score	0.489366 (rank : 94)
Query Neighborhood Hits	431	Target Neighborhood Hits	271	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

AKAP9_HUMAN
θ value	0.0193708 (rank : 119)	NC score	0.063659 (rank : 317)
Query Neighborhood Hits	431	Target Neighborhood Hits	1710	Shared Neighborhood Hits	168
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SRRM1_MOUSE
θ value	0.0193708 (rank : 120)	NC score	0.031228 (rank : 514)
Query Neighborhood Hits	431	Target Neighborhood Hits	966	Shared Neighborhood Hits	81
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CENPE_HUMAN
θ value	0.0252991 (rank : 121)	NC score	0.067988 (rank : 304)
Query Neighborhood Hits	431	Target Neighborhood Hits	2060	Shared Neighborhood Hits	194
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TRI32_HUMAN
θ value	0.0252991 (rank : 122)	NC score	0.492250 (rank : 93)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	113
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

GOGA4_HUMAN
θ value	0.0330416 (rank : 123)	NC score	0.071118 (rank : 294)
Query Neighborhood Hits	431	Target Neighborhood Hits	2034	Shared Neighborhood Hits	200
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

TRIM2_HUMAN
θ value	0.0330416 (rank : 124)	NC score	0.434496 (rank : 105)
Query Neighborhood Hits	431	Target Neighborhood Hits	330	Shared Neighborhood Hits	114
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

PPRB_MOUSE
θ value	0.0431538 (rank : 125)	NC score	0.024999 (rank : 530)
Query Neighborhood Hits	431	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

TRI46_HUMAN
θ value	0.0431538 (rank : 126)	NC score	0.400748 (rank : 108)
Query Neighborhood Hits	431	Target Neighborhood Hits	291	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	0.0431538 (rank : 127)	NC score	0.402163 (rank : 107)
Query Neighborhood Hits	431	Target Neighborhood Hits	287	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

AIM2_HUMAN
θ value	0.0563607 (rank : 128)	NC score	0.026706 (rank : 525)
Query Neighborhood Hits	431	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

TARA_MOUSE
θ value	0.0563607 (rank : 129)	NC score	0.060420 (rank : 336)
Query Neighborhood Hits	431	Target Neighborhood Hits	1133	Shared Neighborhood Hits	156
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRI54_HUMAN
θ value	0.0563607 (rank : 130)	NC score	0.459811 (rank : 100)
Query Neighborhood Hits	431	Target Neighborhood Hits	209	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM3_HUMAN
θ value	0.0563607 (rank : 131)	NC score	0.440851 (rank : 104)
Query Neighborhood Hits	431	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

K1H1_HUMAN
θ value	0.0736092 (rank : 132)	NC score	0.020120 (rank : 545)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	80
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

MRCKB_HUMAN
θ value	0.0736092 (rank : 133)	NC score	0.023941 (rank : 532)
Query Neighborhood Hits	431	Target Neighborhood Hits	2239	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

RP1L1_HUMAN
θ value	0.0736092 (rank : 134)	NC score	0.034391 (rank : 503)
Query Neighborhood Hits	431	Target Neighborhood Hits	1072	Shared Neighborhood Hits	120
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TM108_HUMAN
θ value	0.0736092 (rank : 135)	NC score	0.027884 (rank : 522)
Query Neighborhood Hits	431	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TRI55_HUMAN
θ value	0.0736092 (rank : 136)	NC score	0.486878 (rank : 96)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM2_MOUSE
θ value	0.0736092 (rank : 137)	NC score	0.434057 (rank : 106)
Query Neighborhood Hits	431	Target Neighborhood Hits	331	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

APBB1_HUMAN
θ value	0.0961366 (rank : 138)	NC score	0.015109 (rank : 563)
Query Neighborhood Hits	431	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

LBXCO_MOUSE
θ value	0.0961366 (rank : 139)	NC score	0.027433 (rank : 524)
Query Neighborhood Hits	431	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

PRP1_HUMAN
θ value	0.0961366 (rank : 140)	NC score	0.022217 (rank : 537)
Query Neighborhood Hits	431	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SMC4_MOUSE
θ value	0.0961366 (rank : 141)	NC score	0.048114 (rank : 463)
Query Neighborhood Hits	431	Target Neighborhood Hits	830	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TAF4_HUMAN
θ value	0.0961366 (rank : 142)	NC score	0.033568 (rank : 508)
Query Neighborhood Hits	431	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CF049_HUMAN
θ value	0.125558 (rank : 143)	NC score	0.010536 (rank : 605)
Query Neighborhood Hits	431	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

GOGA4_MOUSE
θ value	0.125558 (rank : 144)	NC score	0.078262 (rank : 274)
Query Neighborhood Hits	431	Target Neighborhood Hits	1939	Shared Neighborhood Hits	209
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

NUP93_HUMAN
θ value	0.125558 (rank : 145)	NC score	0.025773 (rank : 529)
Query Neighborhood Hits	431	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1F7, Q14705	Gene names	NUP93, KIAA0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin).

PHX2B_HUMAN
θ value	0.125558 (rank : 146)	NC score	0.006715 (rank : 633)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	0.125558 (rank : 147)	NC score	0.006715 (rank : 634)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

SM1L2_HUMAN
θ value	0.125558 (rank : 148)	NC score	0.061203 (rank : 329)
Query Neighborhood Hits	431	Target Neighborhood Hits	1019	Shared Neighborhood Hits	144
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

TMC2_HUMAN
θ value	0.125558 (rank : 149)	NC score	0.015818 (rank : 559)
Query Neighborhood Hits	431	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

TRI47_HUMAN
θ value	0.125558 (rank : 150)	NC score	0.538426 (rank : 89)
Query Neighborhood Hits	431	Target Neighborhood Hits	286	Shared Neighborhood Hits	125
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI63_MOUSE
θ value	0.125558 (rank : 151)	NC score	0.503067 (rank : 91)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

FMN2_HUMAN
θ value	0.163984 (rank : 152)	NC score	0.015488 (rank : 560)
Query Neighborhood Hits	431	Target Neighborhood Hits	484	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

GNAS1_HUMAN
θ value	0.163984 (rank : 153)	NC score	0.006670 (rank : 635)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

KIF11_HUMAN
θ value	0.163984 (rank : 154)	NC score	0.024755 (rank : 531)
Query Neighborhood Hits	431	Target Neighborhood Hits	583	Shared Neighborhood Hits	98
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

LETM1_HUMAN
θ value	0.163984 (rank : 155)	NC score	0.045128 (rank : 474)
Query Neighborhood Hits	431	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MARCS_HUMAN
θ value	0.163984 (rank : 156)	NC score	0.027534 (rank : 523)
Query Neighborhood Hits	431	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

TBX2_HUMAN
θ value	0.163984 (rank : 157)	NC score	0.008021 (rank : 622)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

TRI45_MOUSE
θ value	0.163984 (rank : 158)	NC score	0.195867 (rank : 175)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

ANR11_HUMAN
θ value	0.21417 (rank : 159)	NC score	0.017003 (rank : 552)
Query Neighborhood Hits	431	Target Neighborhood Hits	1289	Shared Neighborhood Hits	124
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CO7A1_HUMAN
θ value	0.21417 (rank : 160)	NC score	0.006922 (rank : 631)
Query Neighborhood Hits	431	Target Neighborhood Hits	807	Shared Neighborhood Hits	45
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CTAG2_HUMAN
θ value	0.21417 (rank : 161)	NC score	0.034043 (rank : 505)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

M4K4_MOUSE
θ value	0.21417 (rank : 162)	NC score	0.012323 (rank : 584)
Query Neighborhood Hits	431	Target Neighborhood Hits	1560	Shared Neighborhood Hits	132
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MAGE1_HUMAN
θ value	0.21417 (rank : 163)	NC score	0.016456 (rank : 557)
Query Neighborhood Hits	431	Target Neighborhood Hits	1389	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RB6I2_HUMAN
θ value	0.21417 (rank : 164)	NC score	0.054243 (rank : 402)
Query Neighborhood Hits	431	Target Neighborhood Hits	1584	Shared Neighborhood Hits	169
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SRRM2_MOUSE
θ value	0.21417 (rank : 165)	NC score	0.032629 (rank : 510)
Query Neighborhood Hits	431	Target Neighborhood Hits	1470	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TNNT2_MOUSE
θ value	0.21417 (rank : 166)	NC score	0.034008 (rank : 506)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	73
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

CE016_HUMAN
θ value	0.279714 (rank : 167)	NC score	0.022145 (rank : 538)
Query Neighborhood Hits	431	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

CO1A1_MOUSE
θ value	0.279714 (rank : 168)	NC score	0.013607 (rank : 575)
Query Neighborhood Hits	431	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CUTL1_HUMAN
θ value	0.279714 (rank : 169)	NC score	0.057294 (rank : 363)
Query Neighborhood Hits	431	Target Neighborhood Hits	1574	Shared Neighborhood Hits	175
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DNM3A_MOUSE
θ value	0.279714 (rank : 170)	NC score	0.014823 (rank : 566)
Query Neighborhood Hits	431	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

LAP4_MOUSE
θ value	0.279714 (rank : 171)	NC score	0.000970 (rank : 670)
Query Neighborhood Hits	431	Target Neighborhood Hits	590	Shared Neighborhood Hits	26
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MRIP_HUMAN
θ value	0.279714 (rank : 172)	NC score	0.057219 (rank : 366)
Query Neighborhood Hits	431	Target Neighborhood Hits	578	Shared Neighborhood Hits	96
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MRIP_MOUSE
θ value	0.279714 (rank : 173)	NC score	0.056597 (rank : 374)
Query Neighborhood Hits	431	Target Neighborhood Hits	569	Shared Neighborhood Hits	92
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

T3JAM_HUMAN
θ value	0.279714 (rank : 174)	NC score	0.058706 (rank : 352)
Query Neighborhood Hits	431	Target Neighborhood Hits	533	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TIF1A_MOUSE
θ value	0.279714 (rank : 175)	NC score	0.136635 (rank : 205)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	89
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	0.279714 (rank : 176)	NC score	0.227348 (rank : 154)
Query Neighborhood Hits	431	Target Neighborhood Hits	410	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.279714 (rank : 177)	NC score	0.223822 (rank : 155)
Query Neighborhood Hits	431	Target Neighborhood Hits	498	Shared Neighborhood Hits	117
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TNNT2_HUMAN
θ value	0.279714 (rank : 178)	NC score	0.037238 (rank : 493)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	78
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TRI44_HUMAN
θ value	0.279714 (rank : 179)	NC score	0.528484 (rank : 90)
Query Neighborhood Hits	431	Target Neighborhood Hits	393	Shared Neighborhood Hits	116
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI63_HUMAN
θ value	0.279714 (rank : 180)	NC score	0.499321 (rank : 92)
Query Neighborhood Hits	431	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

CEP57_MOUSE
θ value	0.365318 (rank : 181)	NC score	0.046443 (rank : 467)
Query Neighborhood Hits	431	Target Neighborhood Hits	580	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CF060_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.071540 (rank : 292)
Query Neighborhood Hits	431	Target Neighborhood Hits	1270	Shared Neighborhood Hits	170
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CJ118_MOUSE
θ value	0.365318 (rank : 183)	NC score	0.048659 (rank : 461)
Query Neighborhood Hits	431	Target Neighborhood Hits	1132	Shared Neighborhood Hits	141
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CO1A1_HUMAN
θ value	0.365318 (rank : 184)	NC score	0.012414 (rank : 583)
Query Neighborhood Hits	431	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CP135_HUMAN
θ value	0.365318 (rank : 185)	NC score	0.051735 (rank : 434)
Query Neighborhood Hits	431	Target Neighborhood Hits	1290	Shared Neighborhood Hits	150
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MACF4_HUMAN
θ value	0.365318 (rank : 186)	NC score	0.039466 (rank : 487)
Query Neighborhood Hits	431	Target Neighborhood Hits	1321	Shared Neighborhood Hits	144
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

NOTC3_HUMAN
θ value	0.365318 (rank : 187)	NC score	-0.002458 (rank : 682)
Query Neighborhood Hits	431	Target Neighborhood Hits	1062	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RBCC1_MOUSE
θ value	0.365318 (rank : 188)	NC score	0.062035 (rank : 326)
Query Neighborhood Hits	431	Target Neighborhood Hits	1048	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SFRS2_HUMAN
θ value	0.365318 (rank : 189)	NC score	0.012972 (rank : 579)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
θ value	0.365318 (rank : 190)	NC score	0.012972 (rank : 580)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

SMC1A_HUMAN
θ value	0.365318 (rank : 191)	NC score	0.060561 (rank : 333)
Query Neighborhood Hits	431	Target Neighborhood Hits	1346	Shared Neighborhood Hits	150
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.365318 (rank : 192)	NC score	0.061007 (rank : 330)
Query Neighborhood Hits	431	Target Neighborhood Hits	1384	Shared Neighborhood Hits	155
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TIF1A_HUMAN
θ value	0.365318 (rank : 193)	NC score	0.159611 (rank : 190)
Query Neighborhood Hits	431	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

ZN687_HUMAN
θ value	0.365318 (rank : 194)	NC score	-0.001893 (rank : 680)
Query Neighborhood Hits	431	Target Neighborhood Hits	1244	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CSKI1_MOUSE
θ value	0.47712 (rank : 195)	NC score	0.005925 (rank : 639)
Query Neighborhood Hits	431	Target Neighborhood Hits	1031	Shared Neighborhood Hits	62
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GOGA3_HUMAN
θ value	0.47712 (rank : 196)	NC score	0.062101 (rank : 324)
Query Neighborhood Hits	431	Target Neighborhood Hits	1317	Shared Neighborhood Hits	166
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGB1_HUMAN
θ value	0.47712 (rank : 197)	NC score	0.072498 (rank : 286)
Query Neighborhood Hits	431	Target Neighborhood Hits	2297	Shared Neighborhood Hits	212
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IFT74_HUMAN
θ value	0.47712 (rank : 198)	NC score	0.056295 (rank : 380)
Query Neighborhood Hits	431	Target Neighborhood Hits	949	Shared Neighborhood Hits	132
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

LIPA3_HUMAN
θ value	0.47712 (rank : 199)	NC score	0.044508 (rank : 478)
Query Neighborhood Hits	431	Target Neighborhood Hits	828	Shared Neighborhood Hits	124
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MINK1_HUMAN
θ value	0.47712 (rank : 200)	NC score	0.009925 (rank : 611)
Query Neighborhood Hits	431	Target Neighborhood Hits	1477	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	0.47712 (rank : 201)	NC score	0.007988 (rank : 624)
Query Neighborhood Hits	431	Target Neighborhood Hits	1451	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

RB6I2_MOUSE
θ value	0.47712 (rank : 202)	NC score	0.053035 (rank : 412)
Query Neighborhood Hits	431	Target Neighborhood Hits	1433	Shared Neighborhood Hits	162
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RFIP3_HUMAN
θ value	0.47712 (rank : 203)	NC score	0.060047 (rank : 340)
Query Neighborhood Hits	431	Target Neighborhood Hits	1055	Shared Neighborhood Hits	149
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SYT3_MOUSE
θ value	0.47712 (rank : 204)	NC score	0.002884 (rank : 659)
Query Neighborhood Hits	431	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

TRI44_MOUSE
θ value	0.47712 (rank : 205)	NC score	0.541470 (rank : 88)
Query Neighborhood Hits	431	Target Neighborhood Hits	327	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI54_MOUSE
θ value	0.47712 (rank : 206)	NC score	0.458707 (rank : 101)
Query Neighborhood Hits	431	Target Neighborhood Hits	197	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

ACINU_MOUSE
θ value	0.62314 (rank : 207)	NC score	0.034606 (rank : 501)
Query Neighborhood Hits	431	Target Neighborhood Hits	712	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BASP_HUMAN
θ value	0.62314 (rank : 208)	NC score	0.016671 (rank : 555)
Query Neighborhood Hits	431	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CAC1B_MOUSE
θ value	0.62314 (rank : 209)	NC score	0.007620 (rank : 626)
Query Neighborhood Hits	431	Target Neighborhood Hits	351	Shared Neighborhood Hits	30
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CEP57_HUMAN
θ value	0.62314 (rank : 210)	NC score	0.045984 (rank : 469)
Query Neighborhood Hits	431	Target Neighborhood Hits	576	Shared Neighborhood Hits	109
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

GCC2_MOUSE
θ value	0.62314 (rank : 211)	NC score	0.075015 (rank : 280)
Query Neighborhood Hits	431	Target Neighborhood Hits	1619	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MARCS_MOUSE
θ value	0.62314 (rank : 212)	NC score	0.025842 (rank : 528)
Query Neighborhood Hits	431	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

NDE1_HUMAN
θ value	0.62314 (rank : 213)	NC score	0.057716 (rank : 356)
Query Neighborhood Hits	431	Target Neighborhood Hits	823	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

PLEC1_HUMAN
θ value	0.62314 (rank : 214)	NC score	0.048528 (rank : 462)
Query Neighborhood Hits	431	Target Neighborhood Hits	1326	Shared Neighborhood Hits	160
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SFRS4_HUMAN
θ value	0.62314 (rank : 215)	NC score	0.010554 (rank : 604)
Query Neighborhood Hits	431	Target Neighborhood Hits	384	Shared Neighborhood Hits	28
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

TRHY_HUMAN
θ value	0.62314 (rank : 216)	NC score	0.065974 (rank : 311)
Query Neighborhood Hits	431	Target Neighborhood Hits	1385	Shared Neighborhood Hits	154
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

ABL1_MOUSE
θ value	0.813845 (rank : 217)	NC score	-0.005382 (rank : 686)
Query Neighborhood Hits	431	Target Neighborhood Hits	1178	Shared Neighborhood Hits	43
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ACINU_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.035866 (rank : 498)
Query Neighborhood Hits	431	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ATS12_HUMAN
θ value	0.813845 (rank : 219)	NC score	0.001474 (rank : 667)
Query Neighborhood Hits	431	Target Neighborhood Hits	251	Shared Neighborhood Hits	11
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

DDX10_MOUSE
θ value	0.813845 (rank : 220)	NC score	0.003646 (rank : 655)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

DZIP1_HUMAN
θ value	0.813845 (rank : 221)	NC score	0.035577 (rank : 499)
Query Neighborhood Hits	431	Target Neighborhood Hits	675	Shared Neighborhood Hits	88
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

EPN1_HUMAN
θ value	0.813845 (rank : 222)	NC score	0.010085 (rank : 609)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

FOG1_MOUSE
θ value	0.813845 (rank : 223)	NC score	-0.001976 (rank : 681)
Query Neighborhood Hits	431	Target Neighborhood Hits	1237	Shared Neighborhood Hits	62
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GOGA2_MOUSE
θ value	0.813845 (rank : 224)	NC score	0.051510 (rank : 439)
Query Neighborhood Hits	431	Target Neighborhood Hits	944	Shared Neighborhood Hits	140
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

LIPB1_MOUSE
θ value	0.813845 (rank : 225)	NC score	0.039623 (rank : 485)
Query Neighborhood Hits	431	Target Neighborhood Hits	727	Shared Neighborhood Hits	122
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MYH2_HUMAN
θ value	0.813845 (rank : 226)	NC score	0.046567 (rank : 466)
Query Neighborhood Hits	431	Target Neighborhood Hits	1491	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH9_MOUSE
θ value	0.813845 (rank : 227)	NC score	0.051707 (rank : 435)
Query Neighborhood Hits	431	Target Neighborhood Hits	1829	Shared Neighborhood Hits	190
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO5C_HUMAN
θ value	0.813845 (rank : 228)	NC score	0.045303 (rank : 473)
Query Neighborhood Hits	431	Target Neighborhood Hits	1206	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RECQ4_HUMAN
θ value	0.813845 (rank : 229)	NC score	0.010121 (rank : 608)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

SEP10_MOUSE
θ value	0.813845 (rank : 230)	NC score	0.014344 (rank : 570)
Query Neighborhood Hits	431	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SKI_MOUSE
θ value	0.813845 (rank : 231)	NC score	0.044667 (rank : 477)
Query Neighborhood Hits	431	Target Neighborhood Hits	423	Shared Neighborhood Hits	101
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

SRRM1_HUMAN
θ value	0.813845 (rank : 232)	NC score	0.021462 (rank : 542)
Query Neighborhood Hits	431	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

T22D2_HUMAN
θ value	0.813845 (rank : 233)	NC score	0.017593 (rank : 551)
Query Neighborhood Hits	431	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TCOF_MOUSE
θ value	0.813845 (rank : 234)	NC score	0.016146 (rank : 558)
Query Neighborhood Hits	431	Target Neighborhood Hits	471	Shared Neighborhood Hits	33
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TENS1_HUMAN
θ value	0.813845 (rank : 235)	NC score	0.014587 (rank : 568)
Query Neighborhood Hits	431	Target Neighborhood Hits	400	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

WDR33_HUMAN
θ value	0.813845 (rank : 236)	NC score	0.003269 (rank : 658)
Query Neighborhood Hits	431	Target Neighborhood Hits	638	Shared Neighborhood Hits	30
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

AZI1_MOUSE
θ value	1.06291 (rank : 237)	NC score	0.071447 (rank : 293)
Query Neighborhood Hits	431	Target Neighborhood Hits	990	Shared Neighborhood Hits	150
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CHCH3_HUMAN
θ value	1.06291 (rank : 238)	NC score	0.031328 (rank : 513)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

GA2L1_HUMAN
θ value	1.06291 (rank : 239)	NC score	0.015123 (rank : 562)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

GCC2_HUMAN
θ value	1.06291 (rank : 240)	NC score	0.067783 (rank : 307)
Query Neighborhood Hits	431	Target Neighborhood Hits	1558	Shared Neighborhood Hits	185
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

INCE_MOUSE
θ value	1.06291 (rank : 241)	NC score	0.057540 (rank : 358)
Query Neighborhood Hits	431	Target Neighborhood Hits	903	Shared Neighborhood Hits	131
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

LETM1_MOUSE
θ value	1.06291 (rank : 242)	NC score	0.045741 (rank : 470)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MYH8_MOUSE
θ value	1.06291 (rank : 243)	NC score	0.049155 (rank : 458)
Query Neighborhood Hits	431	Target Neighborhood Hits	1600	Shared Neighborhood Hits	177
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NALP7_HUMAN
θ value	1.06291 (rank : 244)	NC score	0.081250 (rank : 267)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NDE1_MOUSE
θ value	1.06291 (rank : 245)	NC score	0.045519 (rank : 472)
Query Neighborhood Hits	431	Target Neighborhood Hits	602	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

PHLB3_HUMAN
θ value	1.06291 (rank : 246)	NC score	0.039497 (rank : 486)
Query Neighborhood Hits	431	Target Neighborhood Hits	304	Shared Neighborhood Hits	63
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

RBP24_HUMAN
θ value	1.06291 (rank : 247)	NC score	0.067837 (rank : 306)
Query Neighborhood Hits	431	Target Neighborhood Hits	1559	Shared Neighborhood Hits	184
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RERE_HUMAN
θ value	1.06291 (rank : 248)	NC score	0.009534 (rank : 614)
Query Neighborhood Hits	431	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SHAN1_HUMAN
θ value	1.06291 (rank : 249)	NC score	0.005549 (rank : 641)
Query Neighborhood Hits	431	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SKI_HUMAN
θ value	1.06291 (rank : 250)	NC score	0.037106 (rank : 495)
Query Neighborhood Hits	431	Target Neighborhood Hits	423	Shared Neighborhood Hits	96
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

SLK_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.014085 (rank : 573)
Query Neighborhood Hits	431	Target Neighborhood Hits	1775	Shared Neighborhood Hits	151
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SLK_MOUSE
θ value	1.06291 (rank : 252)	NC score	0.014774 (rank : 567)
Query Neighborhood Hits	431	Target Neighborhood Hits	1798	Shared Neighborhood Hits	153
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

T2FA_HUMAN
θ value	1.06291 (rank : 253)	NC score	0.016758 (rank : 554)
Query Neighborhood Hits	431	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TCP10_HUMAN
θ value	1.06291 (rank : 254)	NC score	0.021564 (rank : 541)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

ADA2A_MOUSE
θ value	1.38821 (rank : 255)	NC score	-0.008269 (rank : 691)
Query Neighborhood Hits	431	Target Neighborhood Hits	900	Shared Neighborhood Hits	10
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

BAT2_HUMAN
θ value	1.38821 (rank : 256)	NC score	0.023713 (rank : 534)
Query Neighborhood Hits	431	Target Neighborhood Hits	931	Shared Neighborhood Hits	76
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CAC1B_HUMAN
θ value	1.38821 (rank : 257)	NC score	0.006797 (rank : 632)
Query Neighborhood Hits	431	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CDT1_HUMAN
θ value	1.38821 (rank : 258)	NC score	0.015468 (rank : 561)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

CLIC6_MOUSE
θ value	1.38821 (rank : 259)	NC score	0.007397 (rank : 627)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

DVL2_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.011688 (rank : 592)
Query Neighborhood Hits	431	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DYNA_HUMAN
θ value	1.38821 (rank : 261)	NC score	0.057048 (rank : 367)
Query Neighborhood Hits	431	Target Neighborhood Hits	1194	Shared Neighborhood Hits	163
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

GOGA3_MOUSE
θ value	1.38821 (rank : 262)	NC score	0.057507 (rank : 359)
Query Neighborhood Hits	431	Target Neighborhood Hits	1437	Shared Neighborhood Hits	171
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GPTC8_HUMAN
θ value	1.38821 (rank : 263)	NC score	0.015095 (rank : 564)
Query Neighborhood Hits	431	Target Neighborhood Hits	366	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HOOK1_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.043641 (rank : 479)
Query Neighborhood Hits	431	Target Neighborhood Hits	942	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

INCE_HUMAN
θ value	1.38821 (rank : 265)	NC score	0.065800 (rank : 314)
Query Neighborhood Hits	431	Target Neighborhood Hits	978	Shared Neighborhood Hits	138
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LARP1_HUMAN
θ value	1.38821 (rank : 266)	NC score	0.020827 (rank : 544)
Query Neighborhood Hits	431	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

M4K4_HUMAN
θ value	1.38821 (rank : 267)	NC score	0.011125 (rank : 596)
Query Neighborhood Hits	431	Target Neighborhood Hits	1589	Shared Neighborhood Hits	132
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MY18A_MOUSE
θ value	1.38821 (rank : 268)	NC score	0.056630 (rank : 373)
Query Neighborhood Hits	431	Target Neighborhood Hits	1989	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PRP2_MOUSE
θ value	1.38821 (rank : 269)	NC score	0.014238 (rank : 572)
Query Neighborhood Hits	431	Target Neighborhood Hits	347	Shared Neighborhood Hits	30
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SEP10_HUMAN
θ value	1.38821 (rank : 270)	NC score	0.011122 (rank : 597)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

TRI45_HUMAN
θ value	1.38821 (rank : 271)	NC score	0.206178 (rank : 167)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

AZI1_HUMAN
θ value	1.81305 (rank : 272)	NC score	0.068267 (rank : 302)
Query Neighborhood Hits	431	Target Neighborhood Hits	1000	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BAP31_MOUSE
θ value	1.81305 (rank : 273)	NC score	0.018205 (rank : 550)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

BAT2_MOUSE
θ value	1.81305 (rank : 274)	NC score	0.022084 (rank : 539)
Query Neighborhood Hits	431	Target Neighborhood Hits	947	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CNTRB_MOUSE
θ value	1.81305 (rank : 275)	NC score	0.063405 (rank : 318)
Query Neighborhood Hits	431	Target Neighborhood Hits	1029	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CO5A2_HUMAN
θ value	1.81305 (rank : 276)	NC score	0.011482 (rank : 594)
Query Neighborhood Hits	431	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

COBA1_HUMAN
θ value	1.81305 (rank : 277)	NC score	0.009386 (rank : 616)
Query Neighborhood Hits	431	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

GRIN1_HUMAN
θ value	1.81305 (rank : 278)	NC score	0.028645 (rank : 521)
Query Neighborhood Hits	431	Target Neighborhood Hits	681	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HXA11_HUMAN
θ value	1.81305 (rank : 279)	NC score	0.000337 (rank : 675)
Query Neighborhood Hits	431	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

K1HB_HUMAN
θ value	1.81305 (rank : 280)	NC score	0.021018 (rank : 543)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

LIPA3_MOUSE
θ value	1.81305 (rank : 281)	NC score	0.039744 (rank : 484)
Query Neighborhood Hits	431	Target Neighborhood Hits	636	Shared Neighborhood Hits	112
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MY18A_HUMAN
θ value	1.81305 (rank : 282)	NC score	0.060370 (rank : 338)
Query Neighborhood Hits	431	Target Neighborhood Hits	1929	Shared Neighborhood Hits	189
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH13_HUMAN
θ value	1.81305 (rank : 283)	NC score	0.043415 (rank : 480)
Query Neighborhood Hits	431	Target Neighborhood Hits	1504	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_HUMAN
θ value	1.81305 (rank : 284)	NC score	0.049590 (rank : 457)
Query Neighborhood Hits	431	Target Neighborhood Hits	1610	Shared Neighborhood Hits	177
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH9_HUMAN
θ value	1.81305 (rank : 285)	NC score	0.050009 (rank : 455)
Query Neighborhood Hits	431	Target Neighborhood Hits	1762	Shared Neighborhood Hits	186
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OTU7A_HUMAN
θ value	1.81305 (rank : 286)	NC score	0.008656 (rank : 618)
Query Neighborhood Hits	431	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

PCNT_HUMAN
θ value	1.81305 (rank : 287)	NC score	0.072630 (rank : 285)
Query Neighborhood Hits	431	Target Neighborhood Hits	1551	Shared Neighborhood Hits	187
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

PEPL_MOUSE
θ value	1.81305 (rank : 288)	NC score	0.047566 (rank : 465)
Query Neighborhood Hits	431	Target Neighborhood Hits	1105	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SAS6_MOUSE
θ value	1.81305 (rank : 289)	NC score	0.046371 (rank : 468)
Query Neighborhood Hits	431	Target Neighborhood Hits	931	Shared Neighborhood Hits	125
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

ARMX5_MOUSE
θ value	2.36792 (rank : 290)	NC score	0.007939 (rank : 625)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

ATX2L_MOUSE
θ value	2.36792 (rank : 291)	NC score	0.012284 (rank : 585)
Query Neighborhood Hits	431	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

BSN_MOUSE
θ value	2.36792 (rank : 292)	NC score	0.035904 (rank : 497)
Query Neighborhood Hits	431	Target Neighborhood Hits	2057	Shared Neighborhood Hits	172
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD39_HUMAN
θ value	2.36792 (rank : 293)	NC score	0.048995 (rank : 459)
Query Neighborhood Hits	431	Target Neighborhood Hits	868	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD96_HUMAN
θ value	2.36792 (rank : 294)	NC score	0.038335 (rank : 488)
Query Neighborhood Hits	431	Target Neighborhood Hits	595	Shared Neighborhood Hits	103
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCNL1_HUMAN
θ value	2.36792 (rank : 295)	NC score	0.011721 (rank : 590)
Query Neighborhood Hits	431	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL1_MOUSE
θ value	2.36792 (rank : 296)	NC score	0.010873 (rank : 601)
Query Neighborhood Hits	431	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CSTF2_MOUSE
θ value	2.36792 (rank : 297)	NC score	0.004071 (rank : 652)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

DBP_MOUSE
θ value	2.36792 (rank : 298)	NC score	0.008493 (rank : 619)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	14
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

DVL3_HUMAN
θ value	2.36792 (rank : 299)	NC score	0.010446 (rank : 606)
Query Neighborhood Hits	431	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

FLIP1_MOUSE
θ value	2.36792 (rank : 300)	NC score	0.062782 (rank : 319)
Query Neighborhood Hits	431	Target Neighborhood Hits	1176	Shared Neighborhood Hits	160
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA5_HUMAN
θ value	2.36792 (rank : 301)	NC score	0.048831 (rank : 460)
Query Neighborhood Hits	431	Target Neighborhood Hits	1168	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

HIC2_HUMAN
θ value	2.36792 (rank : 302)	NC score	-0.009649 (rank : 692)
Query Neighborhood Hits	431	Target Neighborhood Hits	820	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

IL3B2_MOUSE
θ value	2.36792 (rank : 303)	NC score	0.013626 (rank : 574)
Query Neighborhood Hits	431	Target Neighborhood Hits	372	Shared Neighborhood Hits	32
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_MOUSE
θ value	2.36792 (rank : 304)	NC score	0.013286 (rank : 577)
Query Neighborhood Hits	431	Target Neighborhood Hits	355	Shared Neighborhood Hits	29
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

INVO_MOUSE
θ value	2.36792 (rank : 305)	NC score	0.037250 (rank : 492)
Query Neighborhood Hits	431	Target Neighborhood Hits	474	Shared Neighborhood Hits	76
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

K1HA_HUMAN
θ value	2.36792 (rank : 306)	NC score	0.021629 (rank : 540)
Query Neighborhood Hits	431	Target Neighborhood Hits	502	Shared Neighborhood Hits	104
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

MBD2_MOUSE
θ value	2.36792 (rank : 307)	NC score	0.014351 (rank : 569)
Query Neighborhood Hits	431	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MOES_MOUSE
θ value	2.36792 (rank : 308)	NC score	0.031339 (rank : 512)
Query Neighborhood Hits	431	Target Neighborhood Hits	923	Shared Neighborhood Hits	127
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MRCKB_MOUSE
θ value	2.36792 (rank : 309)	NC score	0.022840 (rank : 536)
Query Neighborhood Hits	431	Target Neighborhood Hits	2180	Shared Neighborhood Hits	178
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MUC5B_HUMAN
θ value	2.36792 (rank : 310)	NC score	0.005275 (rank : 645)
Query Neighborhood Hits	431	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PML_MOUSE
θ value	2.36792 (rank : 311)	NC score	0.194079 (rank : 176)
Query Neighborhood Hits	431	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

SCG1_MOUSE
θ value	2.36792 (rank : 312)	NC score	0.012584 (rank : 582)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

SEPT9_HUMAN
θ value	2.36792 (rank : 313)	NC score	0.011558 (rank : 593)
Query Neighborhood Hits	431	Target Neighborhood Hits	706	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

SPTN4_HUMAN
θ value	2.36792 (rank : 314)	NC score	0.018859 (rank : 548)
Query Neighborhood Hits	431	Target Neighborhood Hits	570	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

TX13A_HUMAN
θ value	2.36792 (rank : 315)	NC score	0.014999 (rank : 565)
Query Neighborhood Hits	431	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXU3, Q32NB6	Gene names	TEX13A
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 13A protein.

AP3B1_HUMAN
θ value	3.0926 (rank : 316)	NC score	0.003859 (rank : 653)
Query Neighborhood Hits	431	Target Neighborhood Hits	283	Shared Neighborhood Hits	11
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

BSN_HUMAN
θ value	3.0926 (rank : 317)	NC score	0.037075 (rank : 496)
Query Neighborhood Hits	431	Target Neighborhood Hits	1537	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CD2L5_MOUSE
θ value	3.0926 (rank : 318)	NC score	-0.006063 (rank : 687)
Query Neighborhood Hits	431	Target Neighborhood Hits	1011	Shared Neighborhood Hits	32
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CP135_MOUSE
θ value	3.0926 (rank : 319)	NC score	0.052745 (rank : 416)
Query Neighborhood Hits	431	Target Neighborhood Hits	1278	Shared Neighborhood Hits	156
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CP250_HUMAN
θ value	3.0926 (rank : 320)	NC score	0.076207 (rank : 278)
Query Neighborhood Hits	431	Target Neighborhood Hits	1805	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DESP_HUMAN
θ value	3.0926 (rank : 321)	NC score	0.052043 (rank : 430)
Query Neighborhood Hits	431	Target Neighborhood Hits	1470	Shared Neighborhood Hits	169
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EEA1_MOUSE
θ value	3.0926 (rank : 322)	NC score	0.054982 (rank : 395)
Query Neighborhood Hits	431	Target Neighborhood Hits	1637	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

IF4B_HUMAN
θ value	3.0926 (rank : 323)	NC score	0.011931 (rank : 588)
Query Neighborhood Hits	431	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ITF2_HUMAN
θ value	3.0926 (rank : 324)	NC score	0.005385 (rank : 644)
Query Neighborhood Hits	431	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITSN1_MOUSE
θ value	3.0926 (rank : 325)	NC score	0.034208 (rank : 504)
Query Neighborhood Hits	431	Target Neighborhood Hits	1669	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
θ value	3.0926 (rank : 326)	NC score	0.034500 (rank : 502)
Query Neighborhood Hits	431	Target Neighborhood Hits	1371	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

LRCH4_HUMAN
θ value	3.0926 (rank : 327)	NC score	0.000071 (rank : 677)
Query Neighborhood Hits	431	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

MARK4_MOUSE
θ value	3.0926 (rank : 328)	NC score	-0.006847 (rank : 690)
Query Neighborhood Hits	431	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MYH14_MOUSE
θ value	3.0926 (rank : 329)	NC score	0.047592 (rank : 464)
Query Neighborhood Hits	431	Target Neighborhood Hits	1225	Shared Neighborhood Hits	158
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

OSBL5_HUMAN
θ value	3.0926 (rank : 330)	NC score	0.004868 (rank : 647)
Query Neighborhood Hits	431	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

PANK1_MOUSE
θ value	3.0926 (rank : 331)	NC score	0.005970 (rank : 638)
Query Neighborhood Hits	431	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

PI5PA_HUMAN
θ value	3.0926 (rank : 332)	NC score	0.013225 (rank : 578)
Query Neighborhood Hits	431	Target Neighborhood Hits	749	Shared Neighborhood Hits	63
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PIN1_HUMAN
θ value	3.0926 (rank : 333)	NC score	0.008270 (rank : 620)
Query Neighborhood Hits	431	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

SPAG1_HUMAN
θ value	3.0926 (rank : 334)	NC score	0.009041 (rank : 617)
Query Neighborhood Hits	431	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

TBCA_MOUSE
θ value	3.0926 (rank : 335)	NC score	0.018314 (rank : 549)
Query Neighborhood Hits	431	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P48428	Gene names	Tbca
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

CCD46_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.072085 (rank : 291)
Query Neighborhood Hits	431	Target Neighborhood Hits	1430	Shared Neighborhood Hits	188
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DUS8_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.001860 (rank : 666)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DYNA_MOUSE
θ value	4.03905 (rank : 338)	NC score	0.053676 (rank : 406)
Query Neighborhood Hits	431	Target Neighborhood Hits	1084	Shared Neighborhood Hits	152
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

FILA_HUMAN
θ value	4.03905 (rank : 339)	NC score	0.013537 (rank : 576)
Query Neighborhood Hits	431	Target Neighborhood Hits	685	Shared Neighborhood Hits	56
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

HNRPG_MOUSE
θ value	4.03905 (rank : 340)	NC score	0.004181 (rank : 651)
Query Neighborhood Hits	431	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	O35479	Gene names	Rbmx, Hnrnpg, Hnrpg, Rbmxp1, Rbmxrt
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome).

JIP2_MOUSE
θ value	4.03905 (rank : 341)	NC score	0.005984 (rank : 637)
Query Neighborhood Hits	431	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

KI13A_MOUSE
θ value	4.03905 (rank : 342)	NC score	0.011700 (rank : 591)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

MOES_HUMAN
θ value	4.03905 (rank : 343)	NC score	0.029851 (rank : 517)
Query Neighborhood Hits	431	Target Neighborhood Hits	892	Shared Neighborhood Hits	129
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYH14_HUMAN
θ value	4.03905 (rank : 344)	NC score	0.040933 (rank : 482)
Query Neighborhood Hits	431	Target Neighborhood Hits	995	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NUMA1_HUMAN
θ value	4.03905 (rank : 345)	NC score	0.065215 (rank : 316)
Query Neighborhood Hits	431	Target Neighborhood Hits	1523	Shared Neighborhood Hits	179
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

PABP1_HUMAN
θ value	4.03905 (rank : 346)	NC score	0.002533 (rank : 661)
Query Neighborhood Hits	431	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
θ value	4.03905 (rank : 347)	NC score	0.002514 (rank : 662)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PRC1_MOUSE
θ value	4.03905 (rank : 348)	NC score	0.037845 (rank : 489)
Query Neighborhood Hits	431	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

RALY_HUMAN
θ value	4.03905 (rank : 349)	NC score	0.008012 (rank : 623)
Query Neighborhood Hits	431	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

REST_MOUSE
θ value	4.03905 (rank : 350)	NC score	0.055016 (rank : 394)
Query Neighborhood Hits	431	Target Neighborhood Hits	1506	Shared Neighborhood Hits	167
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RRBP1_MOUSE
θ value	4.03905 (rank : 351)	NC score	0.053292 (rank : 408)
Query Neighborhood Hits	431	Target Neighborhood Hits	1650	Shared Neighborhood Hits	194
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SIRT1_HUMAN
θ value	4.03905 (rank : 352)	NC score	0.005461 (rank : 643)
Query Neighborhood Hits	431	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

STIM1_MOUSE
θ value	4.03905 (rank : 353)	NC score	0.040282 (rank : 483)
Query Neighborhood Hits	431	Target Neighborhood Hits	660	Shared Neighborhood Hits	119
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYN2_HUMAN
θ value	4.03905 (rank : 354)	NC score	0.010905 (rank : 600)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TP53B_MOUSE
θ value	4.03905 (rank : 355)	NC score	0.016959 (rank : 553)
Query Neighborhood Hits	431	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ADA19_MOUSE
θ value	5.27518 (rank : 356)	NC score	-0.000949 (rank : 679)
Query Neighborhood Hits	431	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ANR18_HUMAN
θ value	5.27518 (rank : 357)	NC score	0.030716 (rank : 515)
Query Neighborhood Hits	431	Target Neighborhood Hits	1106	Shared Neighborhood Hits	134
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ASPH_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.011956 (rank : 587)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CN045_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.033963 (rank : 507)
Query Neighborhood Hits	431	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

CTGE5_MOUSE
θ value	5.27518 (rank : 360)	NC score	0.051583 (rank : 438)
Query Neighborhood Hits	431	Target Neighborhood Hits	928	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DNM3A_HUMAN
θ value	5.27518 (rank : 361)	NC score	0.010826 (rank : 602)
Query Neighborhood Hits	431	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DVL3_MOUSE
θ value	5.27518 (rank : 362)	NC score	0.009563 (rank : 612)
Query Neighborhood Hits	431	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

HCN4_HUMAN
θ value	5.27518 (rank : 363)	NC score	0.003589 (rank : 656)
Query Neighborhood Hits	431	Target Neighborhood Hits	303	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HORN_HUMAN
θ value	5.27518 (rank : 364)	NC score	0.010344 (rank : 607)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

ISK5_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.007108 (rank : 630)
Query Neighborhood Hits	431	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

KCNH2_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.001896 (rank : 665)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KSR1_HUMAN
θ value	5.27518 (rank : 367)	NC score	-0.005297 (rank : 685)
Query Neighborhood Hits	431	Target Neighborhood Hits	867	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

MYH11_MOUSE
θ value	5.27518 (rank : 368)	NC score	0.056303 (rank : 379)
Query Neighborhood Hits	431	Target Neighborhood Hits	1777	Shared Neighborhood Hits	189
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO10_HUMAN
θ value	5.27518 (rank : 369)	NC score	0.028887 (rank : 520)
Query Neighborhood Hits	431	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO6_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.031774 (rank : 511)
Query Neighborhood Hits	431	Target Neighborhood Hits	727	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

NACAM_MOUSE
θ value	5.27518 (rank : 371)	NC score	0.019389 (rank : 546)
Query Neighborhood Hits	431	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCBP1_MOUSE
θ value	5.27518 (rank : 372)	NC score	0.010033 (rank : 610)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UYV9, Q7TNE8	Gene names	Ncbp1
Domain Architecture	No domain graphic available
Description	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (NCBP 80 kDa subunit) (CBP80).

NIN_MOUSE
θ value	5.27518 (rank : 373)	NC score	0.062547 (rank : 321)
Query Neighborhood Hits	431	Target Neighborhood Hits	1376	Shared Neighborhood Hits	169
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NSD1_MOUSE
θ value	5.27518 (rank : 374)	NC score	0.011863 (rank : 589)
Query Neighborhood Hits	431	Target Neighborhood Hits	472	Shared Neighborhood Hits	40
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PP16B_MOUSE
θ value	5.27518 (rank : 375)	NC score	0.000577 (rank : 673)
Query Neighborhood Hits	431	Target Neighborhood Hits	302	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

RHG06_MOUSE
θ value	5.27518 (rank : 376)	NC score	0.001430 (rank : 668)
Query Neighborhood Hits	431	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SDPR_HUMAN
θ value	5.27518 (rank : 377)	NC score	0.033033 (rank : 509)
Query Neighborhood Hits	431	Target Neighborhood Hits	337	Shared Neighborhood Hits	68
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SOX4_HUMAN
θ value	5.27518 (rank : 378)	NC score	0.000444 (rank : 674)
Query Neighborhood Hits	431	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SYN1_MOUSE
θ value	5.27518 (rank : 379)	NC score	0.011078 (rank : 599)
Query Neighborhood Hits	431	Target Neighborhood Hits	363	Shared Neighborhood Hits	37
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

UBP51_HUMAN
θ value	5.27518 (rank : 380)	NC score	0.000650 (rank : 672)
Query Neighborhood Hits	431	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

AFF4_MOUSE
θ value	6.88961 (rank : 381)	NC score	0.009519 (rank : 615)
Query Neighborhood Hits	431	Target Neighborhood Hits	581	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANR47_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.002386 (rank : 663)
Query Neighborhood Hits	431	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

APOA4_MOUSE
θ value	6.88961 (rank : 383)	NC score	0.034770 (rank : 500)
Query Neighborhood Hits	431	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

ATX2_MOUSE
θ value	6.88961 (rank : 384)	NC score	0.011396 (rank : 595)
Query Neighborhood Hits	431	Target Neighborhood Hits	445	Shared Neighborhood Hits	38
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CABIN_HUMAN
θ value	6.88961 (rank : 385)	NC score	0.014254 (rank : 571)
Query Neighborhood Hits	431	Target Neighborhood Hits	490	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CCAR1_MOUSE
θ value	6.88961 (rank : 386)	NC score	0.019168 (rank : 547)
Query Neighborhood Hits	431	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CHCH3_MOUSE
θ value	6.88961 (rank : 387)	NC score	0.029483 (rank : 518)
Query Neighborhood Hits	431	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

CN145_MOUSE
θ value	6.88961 (rank : 388)	NC score	0.057236 (rank : 365)
Query Neighborhood Hits	431	Target Neighborhood Hits	916	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

DDX21_MOUSE
θ value	6.88961 (rank : 389)	NC score	0.000716 (rank : 671)
Query Neighborhood Hits	431	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DVL2_MOUSE
θ value	6.88961 (rank : 390)	NC score	0.009542 (rank : 613)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

FA47B_HUMAN
θ value	6.88961 (rank : 391)	NC score	0.012188 (rank : 586)
Query Neighborhood Hits	431	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FBN3_HUMAN
θ value	6.88961 (rank : 392)	NC score	-0.003734 (rank : 684)
Query Neighborhood Hits	431	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FGD4_HUMAN
θ value	6.88961 (rank : 393)	NC score	0.001269 (rank : 669)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

FLIP1_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.060534 (rank : 334)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	168
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

IF3A_MOUSE
θ value	6.88961 (rank : 395)	NC score	0.050834 (rank : 446)
Query Neighborhood Hits	431	Target Neighborhood Hits	871	Shared Neighborhood Hits	124
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

INT1_HUMAN
θ value	6.88961 (rank : 396)	NC score	0.005130 (rank : 646)
Query Neighborhood Hits	431	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

JIP3_MOUSE
θ value	6.88961 (rank : 397)	NC score	0.037158 (rank : 494)
Query Neighborhood Hits	431	Target Neighborhood Hits	759	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MYLK2_HUMAN
θ value	6.88961 (rank : 398)	NC score	-0.006369 (rank : 689)
Query Neighborhood Hits	431	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

RECQ5_HUMAN
θ value	6.88961 (rank : 399)	NC score	0.010563 (rank : 603)
Query Neighborhood Hits	431	Target Neighborhood Hits	390	Shared Neighborhood Hits	40
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RGL2_HUMAN
θ value	6.88961 (rank : 400)	NC score	0.004621 (rank : 649)
Query Neighborhood Hits	431	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RGL2_MOUSE
θ value	6.88961 (rank : 401)	NC score	0.004487 (rank : 650)
Query Neighborhood Hits	431	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

SWP70_HUMAN
θ value	6.88961 (rank : 402)	NC score	0.045737 (rank : 471)
Query Neighborhood Hits	431	Target Neighborhood Hits	973	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYN1_HUMAN
θ value	6.88961 (rank : 403)	NC score	0.011113 (rank : 598)
Query Neighborhood Hits	431	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYNJ1_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.006594 (rank : 636)
Query Neighborhood Hits	431	Target Neighborhood Hits	498	Shared Neighborhood Hits	37
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TF3C1_MOUSE
θ value	6.88961 (rank : 405)	NC score	0.005539 (rank : 642)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

UBP37_HUMAN
θ value	6.88961 (rank : 406)	NC score	0.003683 (rank : 654)
Query Neighborhood Hits	431	Target Neighborhood Hits	208	Shared Neighborhood Hits	23
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

ZN524_MOUSE
θ value	6.88961 (rank : 407)	NC score	-0.009899 (rank : 693)
Query Neighborhood Hits	431	Target Neighborhood Hits	712	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.

ARHGF_HUMAN
θ value	8.99809 (rank : 408)	NC score	0.005671 (rank : 640)
Query Neighborhood Hits	431	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

CD016_HUMAN
θ value	8.99809 (rank : 409)	NC score	0.012842 (rank : 581)
Query Neighborhood Hits	431	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

CJ118_HUMAN
θ value	8.99809 (rank : 410)	NC score	0.045016 (rank : 475)
Query Neighborhood Hits	431	Target Neighborhood Hits	937	Shared Neighborhood Hits	126
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CO5A3_HUMAN
θ value	8.99809 (rank : 411)	NC score	0.007264 (rank : 628)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	34
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

DMD_MOUSE
θ value	8.99809 (rank : 412)	NC score	0.041007 (rank : 481)
Query Neighborhood Hits	431	Target Neighborhood Hits	1111	Shared Neighborhood Hits	140
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GOGA6_HUMAN
θ value	8.99809 (rank : 413)	NC score	0.055560 (rank : 386)
Query Neighborhood Hits	431	Target Neighborhood Hits	1007	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

IF2P_HUMAN
θ value	8.99809 (rank : 414)	NC score	0.037669 (rank : 491)
Query Neighborhood Hits	431	Target Neighborhood Hits	889	Shared Neighborhood Hits	106
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

IF3A_HUMAN
θ value	8.99809 (rank : 415)	NC score	0.050905 (rank : 443)
Query Neighborhood Hits	431	Target Neighborhood Hits	875	Shared Neighborhood Hits	126
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IP3KA_HUMAN
θ value	8.99809 (rank : 416)	NC score	0.002865 (rank : 660)
Query Neighborhood Hits	431	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

ITSN2_HUMAN
θ value	8.99809 (rank : 417)	NC score	0.026039 (rank : 527)
Query Neighborhood Hits	431	Target Neighborhood Hits	1173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KIFC2_MOUSE
θ value	8.99809 (rank : 418)	NC score	0.008086 (rank : 621)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	O08672, O08613	Gene names	Kifc2
Domain Architecture
Description	Kinesin-like protein KIFC2.

KTN1_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.052591 (rank : 421)
Query Neighborhood Hits	431	Target Neighborhood Hits	1197	Shared Neighborhood Hits	148
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

LR37A_HUMAN
θ value	8.99809 (rank : 420)	NC score	0.003405 (rank : 657)
Query Neighborhood Hits	431	Target Neighborhood Hits	720	Shared Neighborhood Hits	46
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LTK_HUMAN
θ value	8.99809 (rank : 421)	NC score	-0.006286 (rank : 688)
Query Neighborhood Hits	431	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MYO6_MOUSE
θ value	8.99809 (rank : 422)	NC score	0.028964 (rank : 519)
Query Neighborhood Hits	431	Target Neighborhood Hits	586	Shared Neighborhood Hits	98
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NGN1_MOUSE
θ value	8.99809 (rank : 423)	NC score	-0.000026 (rank : 678)
Query Neighborhood Hits	431	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

PP16B_HUMAN
θ value	8.99809 (rank : 424)	NC score	0.000149 (rank : 676)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

RFX5_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.007167 (rank : 629)
Query Neighborhood Hits	431	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

SMC4_HUMAN
θ value	8.99809 (rank : 426)	NC score	0.044841 (rank : 476)
Query Neighborhood Hits	431	Target Neighborhood Hits	937	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SPTA2_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.026466 (rank : 526)
Query Neighborhood Hits	431	Target Neighborhood Hits	888	Shared Neighborhood Hits	105
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

STAG1_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.002173 (rank : 664)
Query Neighborhood Hits	431	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVM7, O00539	Gene names	STAG1, SA1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

STK10_HUMAN
θ value	8.99809 (rank : 429)	NC score	0.016517 (rank : 556)
Query Neighborhood Hits	431	Target Neighborhood Hits	1921	Shared Neighborhood Hits	162
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TLE2_MOUSE
θ value	8.99809 (rank : 430)	NC score	-0.002595 (rank : 683)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

TRI56_HUMAN
θ value	8.99809 (rank : 431)	NC score	0.312844 (rank : 128)
Query Neighborhood Hits	431	Target Neighborhood Hits	339	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

AMFR2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.106249 (rank : 234)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.105890 (rank : 235)
Query Neighborhood Hits	431	Target Neighborhood Hits	208	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

ANR26_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.056274 (rank : 381)
Query Neighborhood Hits	431	Target Neighborhood Hits	1614	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ARD1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.093209 (rank : 252)
Query Neighborhood Hits	431	Target Neighborhood Hits	621	Shared Neighborhood Hits	75
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

ARD1_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.094746 (rank : 251)
Query Neighborhood Hits	431	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

BARD1_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.104363 (rank : 239)
Query Neighborhood Hits	431	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BARD1_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.101624 (rank : 243)
Query Neighborhood Hits	431	Target Neighborhood Hits	411	Shared Neighborhood Hits	62
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BFAR_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.381365 (rank : 111)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.373031 (rank : 114)
Query Neighborhood Hits	431	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.075293 (rank : 279)
Query Neighborhood Hits	431	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.070638 (rank : 295)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.076514 (rank : 277)
Query Neighborhood Hits	431	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.057893 (rank : 353)
Query Neighborhood Hits	431	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC7_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.223521 (rank : 157)
Query Neighborhood Hits	431	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.092628 (rank : 253)
Query Neighborhood Hits	431	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BPAEA_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.052631 (rank : 418)
Query Neighborhood Hits	431	Target Neighborhood Hits	1480	Shared Neighborhood Hits	167
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRAP_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.083333 (rank : 266)
Query Neighborhood Hits	431	Target Neighborhood Hits	560	Shared Neighborhood Hits	111
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.068385 (rank : 301)
Query Neighborhood Hits	431	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

BRCA1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.367955 (rank : 115)
Query Neighborhood Hits	431	Target Neighborhood Hits	381	Shared Neighborhood Hits	105
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.364140 (rank : 116)
Query Neighborhood Hits	431	Target Neighborhood Hits	436	Shared Neighborhood Hits	111
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

BRE1A_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.073077 (rank : 283)
Query Neighborhood Hits	431	Target Neighborhood Hits	1071	Shared Neighborhood Hits	167
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BRE1A_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.072169 (rank : 290)
Query Neighborhood Hits	431	Target Neighborhood Hits	1025	Shared Neighborhood Hits	167
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

BRE1B_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.091658 (rank : 255)
Query Neighborhood Hits	431	Target Neighborhood Hits	1040	Shared Neighborhood Hits	193
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.090340 (rank : 258)
Query Neighborhood Hits	431	Target Neighborhood Hits	970	Shared Neighborhood Hits	189
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BT3A2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.293140 (rank : 130)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTNL1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.283832 (rank : 132)
Query Neighborhood Hits	431	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

BTNL2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.273607 (rank : 135)
Query Neighborhood Hits	431	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CASP_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.057363 (rank : 361)
Query Neighborhood Hits	431	Target Neighborhood Hits	1131	Shared Neighborhood Hits	156
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.057385 (rank : 360)
Query Neighborhood Hits	431	Target Neighborhood Hits	1152	Shared Neighborhood Hits	154
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CBLB_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.085824 (rank : 263)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	67
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.087368 (rank : 260)
Query Neighborhood Hits	431	Target Neighborhood Hits	277	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.072696 (rank : 284)
Query Neighborhood Hits	431	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.078042 (rank : 275)
Query Neighborhood Hits	431	Target Neighborhood Hits	186	Shared Neighborhood Hits	50
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.091855 (rank : 254)
Query Neighborhood Hits	431	Target Neighborhood Hits	353	Shared Neighborhood Hits	74
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.090391 (rank : 257)
Query Neighborhood Hits	431	Target Neighborhood Hits	426	Shared Neighborhood Hits	85
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CCD19_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.054631 (rank : 398)
Query Neighborhood Hits	431	Target Neighborhood Hits	639	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD27_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.052919 (rank : 414)
Query Neighborhood Hits	431	Target Neighborhood Hits	594	Shared Neighborhood Hits	111
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD41_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.062588 (rank : 320)
Query Neighborhood Hits	431	Target Neighborhood Hits	1139	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.067978 (rank : 305)
Query Neighborhood Hits	431	Target Neighborhood Hits	1399	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.066744 (rank : 309)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	169
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD91_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.052446 (rank : 423)
Query Neighborhood Hits	431	Target Neighborhood Hits	868	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CD276_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.138767 (rank : 202)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.153916 (rank : 194)
Query Neighborhood Hits	431	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD80_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.054582 (rank : 399)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

CD80_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.070512 (rank : 296)
Query Neighborhood Hits	431	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CD86_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.116863 (rank : 223)
Query Neighborhood Hits	431	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

CD86_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.111294 (rank : 231)
Query Neighborhood Hits	431	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

CE152_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.053927 (rank : 404)
Query Neighborhood Hits	431	Target Neighborhood Hits	976	Shared Neighborhood Hits	141
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.060371 (rank : 337)
Query Neighborhood Hits	431	Target Neighborhood Hits	1553	Shared Neighborhood Hits	177
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPF_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.068803 (rank : 300)
Query Neighborhood Hits	431	Target Neighborhood Hits	1932	Shared Neighborhood Hits	204
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CEP55_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.051218 (rank : 441)
Query Neighborhood Hits	431	Target Neighborhood Hits	693	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP63_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.055107 (rank : 391)
Query Neighborhood Hits	431	Target Neighborhood Hits	1005	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CHFR_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.223129 (rank : 159)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.216216 (rank : 160)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	76
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CI039_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.052726 (rank : 417)
Query Neighborhood Hits	431	Target Neighborhood Hits	1171	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CI093_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.054216 (rank : 403)
Query Neighborhood Hits	431	Target Neighborhood Hits	1088	Shared Neighborhood Hits	148
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CING_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.050800 (rank : 447)
Query Neighborhood Hits	431	Target Neighborhood Hits	1275	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CING_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.057632 (rank : 357)
Query Neighborhood Hits	431	Target Neighborhood Hits	1432	Shared Neighborhood Hits	170
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CK5P2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.050627 (rank : 448)
Query Neighborhood Hits	431	Target Neighborhood Hits	1433	Shared Neighborhood Hits	167
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CM007_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.165378 (rank : 183)
Query Neighborhood Hits	431	Target Neighborhood Hits	422	Shared Neighborhood Hits	105
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.185704 (rank : 180)
Query Neighborhood Hits	431	Target Neighborhood Hits	416	Shared Neighborhood Hits	103
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CN145_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.056143 (rank : 383)
Query Neighborhood Hits	431	Target Neighborhood Hits	1196	Shared Neighborhood Hits	151
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CNOT4_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.080605 (rank : 270)
Query Neighborhood Hits	431	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.078500 (rank : 273)
Query Neighborhood Hits	431	Target Neighborhood Hits	277	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNTRB_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.054326 (rank : 401)
Query Neighborhood Hits	431	Target Neighborhood Hits	690	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP250_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.062452 (rank : 323)
Query Neighborhood Hits	431	Target Neighborhood Hits	1583	Shared Neighborhood Hits	184
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CROCC_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.055489 (rank : 389)
Query Neighborhood Hits	431	Target Neighborhood Hits	1409	Shared Neighborhood Hits	166
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.055536 (rank : 387)
Query Neighborhood Hits	431	Target Neighborhood Hits	1460	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT096_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.056702 (rank : 372)
Query Neighborhood Hits	431	Target Neighborhood Hits	438	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

CT2NL_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.065950 (rank : 312)
Query Neighborhood Hits	431	Target Neighborhood Hits	1059	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CT2NL_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.059276 (rank : 347)
Query Neighborhood Hits	431	Target Neighborhood Hits	902	Shared Neighborhood Hits	143
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CUTL1_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.052384 (rank : 424)
Query Neighborhood Hits	431	Target Neighborhood Hits	1620	Shared Neighborhood Hits	175
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CXAR_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.056420 (rank : 377)
Query Neighborhood Hits	431	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.056258 (rank : 382)
Query Neighborhood Hits	431	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

CYLN2_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.052458 (rank : 422)
Query Neighborhood Hits	431	Target Neighborhood Hits	1002	Shared Neighborhood Hits	142
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.050005 (rank : 456)
Query Neighborhood Hits	431	Target Neighborhood Hits	1138	Shared Neighborhood Hits	162
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DTX3L_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.073453 (rank : 282)
Query Neighborhood Hits	431	Target Neighborhood Hits	187	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.207771 (rank : 166)
Query Neighborhood Hits	431	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.214667 (rank : 164)
Query Neighborhood Hits	431	Target Neighborhood Hits	202	Shared Neighborhood Hits	71
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

EEA1_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.059602 (rank : 342)
Query Neighborhood Hits	431	Target Neighborhood Hits	1796	Shared Neighborhood Hits	185
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EP15R_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.054528 (rank : 400)
Query Neighborhood Hits	431	Target Neighborhood Hits	1083	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

FSD1L_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.060498 (rank : 335)
Query Neighborhood Hits	431	Target Neighborhood Hits	78	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCC1_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.067513 (rank : 308)
Query Neighborhood Hits	431	Target Neighborhood Hits	887	Shared Neighborhood Hits	142
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.059183 (rank : 348)
Query Neighborhood Hits	431	Target Neighborhood Hits	777	Shared Neighborhood Hits	131
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGA1_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.059598 (rank : 343)
Query Neighborhood Hits	431	Target Neighborhood Hits	1222	Shared Neighborhood Hits	163
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA1_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.050399 (rank : 452)
Query Neighborhood Hits	431	Target Neighborhood Hits	994	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA5_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.052316 (rank : 427)
Query Neighborhood Hits	431	Target Neighborhood Hits	1434	Shared Neighborhood Hits	166
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GRAP1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.052360 (rank : 426)
Query Neighborhood Hits	431	Target Neighborhood Hits	1234	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HHLA2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.118912 (rank : 222)
Query Neighborhood Hits	431	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMMR_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.050067 (rank : 454)
Query Neighborhood Hits	431	Target Neighborhood Hits	1082	Shared Neighborhood Hits	140
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HMMR_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.055101 (rank : 392)
Query Neighborhood Hits	431	Target Neighborhood Hits	1178	Shared Neighborhood Hits	155
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

ICOSL_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.134116 (rank : 206)
Query Neighborhood Hits	431	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

ICOSL_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.107608 (rank : 233)
Query Neighborhood Hits	431	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

IFT74_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.052992 (rank : 413)
Query Neighborhood Hits	431	Target Neighborhood Hits	939	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.050869 (rank : 444)
Query Neighborhood Hits	431	Target Neighborhood Hits	893	Shared Neighborhood Hits	138
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

K0555_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.051695 (rank : 436)
Query Neighborhood Hits	431	Target Neighborhood Hits	880	Shared Neighborhood Hits	131
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KTN1_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.053564 (rank : 407)
Query Neighborhood Hits	431	Target Neighborhood Hits	1324	Shared Neighborhood Hits	160
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LIPA2_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.051173 (rank : 442)
Query Neighborhood Hits	431	Target Neighborhood Hits	1282	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LNX1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.160726 (rank : 189)
Query Neighborhood Hits	431	Target Neighborhood Hits	379	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.164548 (rank : 184)
Query Neighborhood Hits	431	Target Neighborhood Hits	377	Shared Neighborhood Hits	87
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.153818 (rank : 195)
Query Neighborhood Hits	431	Target Neighborhood Hits	389	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LNX2_MOUSE
θ value	θ > 10 (rank : 533)	NC score	0.155456 (rank : 193)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LRC45_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.055497 (rank : 388)
Query Neighborhood Hits	431	Target Neighborhood Hits	933	Shared Neighborhood Hits	143
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.059535 (rank : 344)
Query Neighborhood Hits	431	Target Neighborhood Hits	959	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRSM1_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.066445 (rank : 310)
Query Neighborhood Hits	431	Target Neighborhood Hits	1078	Shared Neighborhood Hits	155
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MAT1_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.119053 (rank : 220)
Query Neighborhood Hits	431	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.118979 (rank : 221)
Query Neighborhood Hits	431	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

MD1L1_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.051806 (rank : 432)
Query Neighborhood Hits	431	Target Neighborhood Hits	1001	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MGRN1_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.061740 (rank : 327)
Query Neighborhood Hits	431	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.062453 (rank : 322)
Query Neighborhood Hits	431	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MIB1_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.056958 (rank : 369)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	57
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.056955 (rank : 370)
Query Neighborhood Hits	431	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MKRN2_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.059041 (rank : 349)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

MKRN2_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.059365 (rank : 346)
Query Neighborhood Hits	431	Target Neighborhood Hits	130	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

MKRN4_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.052375 (rank : 425)
Query Neighborhood Hits	431	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

MNAB_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.102548 (rank : 242)
Query Neighborhood Hits	431	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.101267 (rank : 244)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MOG_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.264645 (rank : 138)
Query Neighborhood Hits	431	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MOG_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.264111 (rank : 140)
Query Neighborhood Hits	431	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

MYH10_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.051453 (rank : 440)
Query Neighborhood Hits	431	Target Neighborhood Hits	1620	Shared Neighborhood Hits	183
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.051873 (rank : 431)
Query Neighborhood Hits	431	Target Neighborhood Hits	1612	Shared Neighborhood Hits	180
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.056449 (rank : 376)
Query Neighborhood Hits	431	Target Neighborhood Hits	1806	Shared Neighborhood Hits	194
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NAL11_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.072425 (rank : 288)
Query Neighborhood Hits	431	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL13_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.072195 (rank : 289)
Query Neighborhood Hits	431	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP1_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.079412 (rank : 272)
Query Neighborhood Hits	431	Target Neighborhood Hits	138	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.072470 (rank : 287)
Query Neighborhood Hits	431	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP6_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.089046 (rank : 259)
Query Neighborhood Hits	431	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NEST_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.059773 (rank : 341)
Query Neighborhood Hits	431	Target Neighborhood Hits	1305	Shared Neighborhood Hits	169
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NEUL1_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.056017 (rank : 385)
Query Neighborhood Hits	431	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.053750 (rank : 405)
Query Neighborhood Hits	431	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.110996 (rank : 232)
Query Neighborhood Hits	431	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.112822 (rank : 229)
Query Neighborhood Hits	431	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NIN_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.065936 (rank : 313)
Query Neighborhood Hits	431	Target Neighborhood Hits	1416	Shared Neighborhood Hits	166
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

OPTN_MOUSE
θ value	θ > 10 (rank : 565)	NC score	0.051745 (rank : 433)
Query Neighborhood Hits	431	Target Neighborhood Hits	1120	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PCGF2_HUMAN
θ value	θ > 10 (rank : 566)	NC score	0.128573 (rank : 212)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.128378 (rank : 213)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	54
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.137507 (rank : 204)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.138270 (rank : 203)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF6_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.157366 (rank : 192)
Query Neighborhood Hits	431	Target Neighborhood Hits	178	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.162819 (rank : 186)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	60
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCNT_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.057858 (rank : 354)
Query Neighborhood Hits	431	Target Neighborhood Hits	1207	Shared Neighborhood Hits	165
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDL1_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.095158 (rank : 250)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.125841 (rank : 215)
Query Neighborhood Hits	431	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.104290 (rank : 240)
Query Neighborhood Hits	431	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.097861 (rank : 247)
Query Neighborhood Hits	431	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PEPL_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.050561 (rank : 449)
Query Neighborhood Hits	431	Target Neighborhood Hits	1141	Shared Neighborhood Hits	145
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEX10_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.344906 (rank : 119)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PHLB2_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.052307 (rank : 428)
Query Neighborhood Hits	431	Target Neighborhood Hits	964	Shared Neighborhood Hits	141
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PHLB2_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.053132 (rank : 411)
Query Neighborhood Hits	431	Target Neighborhood Hits	1016	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PIBF1_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.050399 (rank : 453)
Query Neighborhood Hits	431	Target Neighborhood Hits	1041	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PJA1_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.060940 (rank : 331)
Query Neighborhood Hits	431	Target Neighborhood Hits	159	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

PML_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.223290 (rank : 158)
Query Neighborhood Hits	431	Target Neighborhood Hits	248	Shared Neighborhood Hits	98
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PZRN3_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.130651 (rank : 211)
Query Neighborhood Hits	431	Target Neighborhood Hits	461	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 585)	NC score	0.133104 (rank : 207)
Query Neighborhood Hits	431	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.131187 (rank : 209)
Query Neighborhood Hits	431	Target Neighborhood Hits	438	Shared Neighborhood Hits	92
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.158945 (rank : 191)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.169800 (rank : 182)
Query Neighborhood Hits	431	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RABE1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.059495 (rank : 345)
Query Neighborhood Hits	431	Target Neighborhood Hits	1104	Shared Neighborhood Hits	156
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.060599 (rank : 332)
Query Neighborhood Hits	431	Target Neighborhood Hits	1105	Shared Neighborhood Hits	160
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RAD18_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.193208 (rank : 178)
Query Neighborhood Hits	431	Target Neighborhood Hits	284	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.214794 (rank : 162)
Query Neighborhood Hits	431	Target Neighborhood Hits	230	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAD50_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.052172 (rank : 429)
Query Neighborhood Hits	431	Target Neighborhood Hits	1317	Shared Neighborhood Hits	147
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.053227 (rank : 409)
Query Neighborhood Hits	431	Target Neighborhood Hits	1366	Shared Neighborhood Hits	158
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAG1_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.282664 (rank : 133)
Query Neighborhood Hits	431	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.272981 (rank : 136)
Query Neighborhood Hits	431	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RBBP6_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.123583 (rank : 219)
Query Neighborhood Hits	431	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.131605 (rank : 208)
Query Neighborhood Hits	431	Target Neighborhood Hits	1014	Shared Neighborhood Hits	125
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBCC1_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.056817 (rank : 371)
Query Neighborhood Hits	431	Target Neighborhood Hits	1023	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RC3H1_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.145234 (rank : 200)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	95
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

RC3H1_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.149645 (rank : 197)
Query Neighborhood Hits	431	Target Neighborhood Hits	244	Shared Neighborhood Hits	81
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

REST_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.060133 (rank : 339)
Query Neighborhood Hits	431	Target Neighborhood Hits	1605	Shared Neighborhood Hits	175
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RFFL_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.057260 (rank : 364)
Query Neighborhood Hits	431	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.055487 (rank : 390)
Query Neighborhood Hits	431	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RFIP4_MOUSE
θ value	θ > 10 (rank : 605)	NC score	0.050853 (rank : 445)
Query Neighborhood Hits	431	Target Neighborhood Hits	708	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

RFWD2_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.194037 (rank : 177)
Query Neighborhood Hits	431	Target Neighborhood Hits	518	Shared Neighborhood Hits	92
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.193157 (rank : 179)
Query Neighborhood Hits	431	Target Neighborhood Hits	535	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.269583 (rank : 137)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	83
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.264161 (rank : 139)
Query Neighborhood Hits	431	Target Neighborhood Hits	220	Shared Neighborhood Hits	84
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.244486 (rank : 145)
Query Neighborhood Hits	431	Target Neighborhood Hits	201	Shared Neighborhood Hits	76
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.244465 (rank : 146)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RINI_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.054709 (rank : 396)
Query Neighborhood Hits	431	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.054675 (rank : 397)
Query Neighborhood Hits	431	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RKHD1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.076702 (rank : 276)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RN123_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.069705 (rank : 299)
Query Neighborhood Hits	431	Target Neighborhood Hits	175	Shared Neighborhood Hits	52
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN123_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.070491 (rank : 297)
Query Neighborhood Hits	431	Target Neighborhood Hits	174	Shared Neighborhood Hits	53
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

RN125_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.322675 (rank : 125)
Query Neighborhood Hits	431	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.332846 (rank : 122)
Query Neighborhood Hits	431	Target Neighborhood Hits	220	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN141_HUMAN
θ value	θ > 10 (rank : 619)	NC score	0.199101 (rank : 170)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 620)	NC score	0.197650 (rank : 173)
Query Neighborhood Hits	431	Target Neighborhood Hits	200	Shared Neighborhood Hits	74
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.214757 (rank : 163)
Query Neighborhood Hits	431	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.213439 (rank : 165)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN152_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.114166 (rank : 227)
Query Neighborhood Hits	431	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.115900 (rank : 225)
Query Neighborhood Hits	431	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN166_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.329284 (rank : 123)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	81
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.323171 (rank : 124)
Query Neighborhood Hits	431	Target Neighborhood Hits	248	Shared Neighborhood Hits	86
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN168_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.349915 (rank : 117)
Query Neighborhood Hits	431	Target Neighborhood Hits	370	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN168_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.334377 (rank : 121)
Query Neighborhood Hits	431	Target Neighborhood Hits	440	Shared Neighborhood Hits	138
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN169_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.286345 (rank : 131)
Query Neighborhood Hits	431	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN183_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.280206 (rank : 134)
Query Neighborhood Hits	431	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.231939 (rank : 153)
Query Neighborhood Hits	431	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN185_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.248089 (rank : 144)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.248251 (rank : 143)
Query Neighborhood Hits	431	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.090476 (rank : 256)
Query Neighborhood Hits	431	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF32_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.081128 (rank : 268)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.079550 (rank : 271)
Query Neighborhood Hits	431	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.080847 (rank : 269)
Query Neighborhood Hits	431	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RNF41_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.243714 (rank : 148)
Query Neighborhood Hits	431	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.243866 (rank : 147)
Query Neighborhood Hits	431	Target Neighborhood Hits	224	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.240289 (rank : 151)
Query Neighborhood Hits	431	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.233000 (rank : 152)
Query Neighborhood Hits	431	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.242052 (rank : 149)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.240919 (rank : 150)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.303714 (rank : 129)
Query Neighborhood Hits	431	Target Neighborhood Hits	622	Shared Neighborhood Hits	155
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.316956 (rank : 126)
Query Neighborhood Hits	431	Target Neighborhood Hits	618	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RRBP1_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.051619 (rank : 437)
Query Neighborhood Hits	431	Target Neighborhood Hits	1306	Shared Neighborhood Hits	173
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RUFY2_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.055085 (rank : 393)
Query Neighborhood Hits	431	Target Neighborhood Hits	1208	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SDCG8_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.057309 (rank : 362)
Query Neighborhood Hits	431	Target Neighborhood Hits	1002	Shared Neighborhood Hits	146
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.056342 (rank : 378)
Query Neighborhood Hits	431	Target Neighborhood Hits	886	Shared Neighborhood Hits	132
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SM1L2_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.052601 (rank : 420)
Query Neighborhood Hits	431	Target Neighborhood Hits	918	Shared Neighborhood Hits	135
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

SMC2_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.057785 (rank : 355)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	160
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC3_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.050459 (rank : 451)
Query Neighborhood Hits	431	Target Neighborhood Hits	1186	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.050488 (rank : 450)
Query Neighborhood Hits	431	Target Neighborhood Hits	1187	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMRA3_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.198938 (rank : 171)
Query Neighborhood Hits	431	Target Neighborhood Hits	265	Shared Neighborhood Hits	84
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.185416 (rank : 181)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SWP70_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.052845 (rank : 415)
Query Neighborhood Hits	431	Target Neighborhood Hits	1097	Shared Neighborhood Hits	147
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SYCP1_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.052611 (rank : 419)
Query Neighborhood Hits	431	Target Neighborhood Hits	1313	Shared Neighborhood Hits	155
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP1_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.065331 (rank : 315)
Query Neighborhood Hits	431	Target Neighborhood Hits	1456	Shared Neighborhood Hits	177
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TARA_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.053134 (rank : 410)
Query Neighborhood Hits	431	Target Neighborhood Hits	1626	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TOPRS_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.112201 (rank : 230)
Query Neighborhood Hits	431	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.115138 (rank : 226)
Query Neighborhood Hits	431	Target Neighborhood Hits	263	Shared Neighborhood Hits	54
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TPR_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.062068 (rank : 325)
Query Neighborhood Hits	431	Target Neighborhood Hits	1921	Shared Neighborhood Hits	190
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRAF2_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.113307 (rank : 228)
Query Neighborhood Hits	431	Target Neighborhood Hits	402	Shared Neighborhood Hits	87
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.115993 (rank : 224)
Query Neighborhood Hits	431	Target Neighborhood Hits	394	Shared Neighborhood Hits	84
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.096420 (rank : 249)
Query Neighborhood Hits	431	Target Neighborhood Hits	463	Shared Neighborhood Hits	123
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.103862 (rank : 241)
Query Neighborhood Hits	431	Target Neighborhood Hits	476	Shared Neighborhood Hits	130
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.125255 (rank : 217)
Query Neighborhood Hits	431	Target Neighborhood Hits	373	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.058977 (rank : 351)
Query Neighborhood Hits	431	Target Neighborhood Hits	338	Shared Neighborhood Hits	48
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

TRAF5_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.143145 (rank : 201)
Query Neighborhood Hits	431	Target Neighborhood Hits	396	Shared Neighborhood Hits	126
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.161336 (rank : 187)
Query Neighborhood Hits	431	Target Neighborhood Hits	355	Shared Neighborhood Hits	116
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRAF6_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.215512 (rank : 161)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRAF6_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.223636 (rank : 156)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	84
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRAF7_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.126048 (rank : 214)
Query Neighborhood Hits	431	Target Neighborhood Hits	482	Shared Neighborhood Hits	90
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF7_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.125476 (rank : 216)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	88
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAIP_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.146191 (rank : 198)
Query Neighborhood Hits	431	Target Neighborhood Hits	780	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

TRAIP_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.131094 (rank : 210)
Query Neighborhood Hits	431	Target Neighborhood Hits	745	Shared Neighborhood Hits	142
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TRI42_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.263283 (rank : 142)
Query Neighborhood Hits	431	Target Neighborhood Hits	283	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.263516 (rank : 141)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI56_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.312911 (rank : 127)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	99
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI66_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.070236 (rank : 298)
Query Neighborhood Hits	431	Target Neighborhood Hits	479	Shared Neighborhood Hits	89
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.073795 (rank : 281)
Query Neighborhood Hits	431	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRIPB_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.059031 (rank : 350)
Query Neighborhood Hits	431	Target Neighborhood Hits	1587	Shared Neighborhood Hits	173
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UACA_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.056489 (rank : 375)
Query Neighborhood Hits	431	Target Neighborhood Hits	1622	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UB7I3_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.068252 (rank : 303)
Query Neighborhood Hits	431	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.084220 (rank : 265)
Query Neighborhood Hits	431	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

UHRF1_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.153319 (rank : 196)
Query Neighborhood Hits	431	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.163013 (rank : 185)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.202040 (rank : 169)
Query Neighborhood Hits	431	Target Neighborhood Hits	269	Shared Neighborhood Hits	87
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.197591 (rank : 174)
Query Neighborhood Hits	431	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZN179_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.487505 (rank : 95)
Query Neighborhood Hits	431	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN313_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.341140 (rank : 120)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.349726 (rank : 118)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

ZSWM2_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.061287 (rank : 328)
Query Neighborhood Hits	431	Target Neighborhood Hits	151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

MEFV_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	431	Target Neighborhood Hits	431	Shared Neighborhood Hits	431
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TRI27_MOUSE
NC score	0.932855 (rank : 2)	θ value	4.34313e-95 (rank : 4)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	125
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI27_HUMAN
NC score	0.932221 (rank : 3)	θ value	3.00772e-96 (rank : 3)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	130
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI68_HUMAN
NC score	0.916563 (rank : 4)	θ value	2.65945e-60 (rank : 8)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	120
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI68_MOUSE
NC score	0.913268 (rank : 5)	θ value	2.25136e-59 (rank : 9)
Query Neighborhood Hits	431	Target Neighborhood Hits	356	Shared Neighborhood Hits	144
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI38_HUMAN
NC score	0.911118 (rank : 6)	θ value	3.2585e-50 (rank : 18)
Query Neighborhood Hits	431	Target Neighborhood Hits	373	Shared Neighborhood Hits	154
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI11_MOUSE
NC score	0.910800 (rank : 7)	θ value	1.97229e-55 (rank : 12)
Query Neighborhood Hits	431	Target Neighborhood Hits	329	Shared Neighborhood Hits	134
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI41_HUMAN
NC score	0.910484 (rank : 8)	θ value	3.99248e-40 (rank : 33)
Query Neighborhood Hits	431	Target Neighborhood Hits	349	Shared Neighborhood Hits	156
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI11_HUMAN
NC score	0.909791 (rank : 9)	θ value	1.61343e-57 (rank : 10)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	131
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRIM7_HUMAN
NC score	0.908692 (rank : 10)	θ value	5.93839e-52 (rank : 16)
Query Neighborhood Hits	431	Target Neighborhood Hits	336	Shared Neighborhood Hits	146
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI60_MOUSE
NC score	0.907422 (rank : 11)	θ value	2.19075e-38 (rank : 36)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI15_HUMAN
NC score	0.906162 (rank : 12)	θ value	4.70527e-49 (rank : 19)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRIM7_MOUSE
NC score	0.906000 (rank : 13)	θ value	9.78833e-55 (rank : 14)
Query Neighborhood Hits	431	Target Neighborhood Hits	358	Shared Neighborhood Hits	153
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

RO52_MOUSE
NC score	0.904686 (rank : 14)	θ value	5.73848e-55 (rank : 13)
Query Neighborhood Hits	431	Target Neighborhood Hits	360	Shared Neighborhood Hits	135
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RO52_HUMAN
NC score	0.903569 (rank : 15)	θ value	5.00389e-67 (rank : 7)
Query Neighborhood Hits	431	Target Neighborhood Hits	419	Shared Neighborhood Hits	152
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI17_HUMAN
NC score	0.900415 (rank : 16)	θ value	2.95404e-43 (rank : 26)
Query Neighborhood Hits	431	Target Neighborhood Hits	318	Shared Neighborhood Hits	136
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI60_HUMAN
NC score	0.898061 (rank : 17)	θ value	1.04822e-48 (rank : 20)
Query Neighborhood Hits	431	Target Neighborhood Hits	357	Shared Neighborhood Hits	143
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRI10_MOUSE
NC score	0.894396 (rank : 18)	θ value	8.30557e-46 (rank : 24)
Query Neighborhood Hits	431	Target Neighborhood Hits	285	Shared Neighborhood Hits	126
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI39_MOUSE
NC score	0.894285 (rank : 19)	θ value	2.93355e-67 (rank : 6)
Query Neighborhood Hits	431	Target Neighborhood Hits	691	Shared Neighborhood Hits	212
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_HUMAN
NC score	0.892336 (rank : 20)	θ value	1.5555e-68 (rank : 5)
Query Neighborhood Hits	431	Target Neighborhood Hits	693	Shared Neighborhood Hits	208
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI10_HUMAN
NC score	0.892245 (rank : 21)	θ value	2.85459e-46 (rank : 22)
Query Neighborhood Hits	431	Target Neighborhood Hits	315	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

ERMAP_HUMAN
NC score	0.888785 (rank : 22)	θ value	3.974e-56 (rank : 11)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	80
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

RFPL3_HUMAN
NC score	0.887945 (rank : 23)	θ value	1.01765e-35 (rank : 42)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	92
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFPL1_HUMAN
NC score	0.887313 (rank : 24)	θ value	3.4976e-36 (rank : 38)
Query Neighborhood Hits	431	Target Neighborhood Hits	119	Shared Neighborhood Hits	90
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRIM6_HUMAN
NC score	0.885550 (rank : 25)	θ value	1.04822e-48 (rank : 21)
Query Neighborhood Hits	431	Target Neighborhood Hits	412	Shared Neighborhood Hits	158
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI17_MOUSE
NC score	0.885197 (rank : 26)	θ value	6.35935e-46 (rank : 23)
Query Neighborhood Hits	431	Target Neighborhood Hits	620	Shared Neighborhood Hits	199
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI34_MOUSE
NC score	0.884379 (rank : 27)	θ value	3.26607e-42 (rank : 28)
Query Neighborhood Hits	431	Target Neighborhood Hits	332	Shared Neighborhood Hits	146
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRIM6_MOUSE
NC score	0.883742 (rank : 28)	θ value	2.49495e-50 (rank : 17)
Query Neighborhood Hits	431	Target Neighborhood Hits	451	Shared Neighborhood Hits	172
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

RFPL2_HUMAN
NC score	0.882307 (rank : 29)	θ value	8.61488e-35 (rank : 44)
Query Neighborhood Hits	431	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

TRIM4_HUMAN
NC score	0.877764 (rank : 30)	θ value	3.17079e-29 (rank : 52)
Query Neighborhood Hits	431	Target Neighborhood Hits	321	Shared Neighborhood Hits	137
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI62_MOUSE
NC score	0.872968 (rank : 31)	θ value	3.4976e-36 (rank : 39)
Query Neighborhood Hits	431	Target Neighborhood Hits	478	Shared Neighborhood Hits	169
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI49_HUMAN
NC score	0.872951 (rank : 32)	θ value	3.3877e-31 (rank : 51)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	115
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI62_HUMAN
NC score	0.869396 (rank : 33)	θ value	5.96599e-36 (rank : 41)
Query Neighborhood Hits	431	Target Neighborhood Hits	584	Shared Neighborhood Hits	191
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM5_HUMAN
NC score	0.867459 (rank : 34)	θ value	8.89434e-40 (rank : 34)
Query Neighborhood Hits	431	Target Neighborhood Hits	424	Shared Neighborhood Hits	159
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRI34_HUMAN
NC score	0.867302 (rank : 35)	θ value	1.91475e-42 (rank : 27)
Query Neighborhood Hits	431	Target Neighborhood Hits	416	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI43_HUMAN
NC score	0.865544 (rank : 36)	θ value	1.98606e-31 (rank : 50)
Query Neighborhood Hits	431	Target Neighborhood Hits	341	Shared Neighborhood Hits	141
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

ERMAP_MOUSE
NC score	0.858788 (rank : 37)	θ value	2.18062e-54 (rank : 15)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

TRI50_MOUSE
NC score	0.853896 (rank : 38)	θ value	5.584e-34 (rank : 45)
Query Neighborhood Hits	431	Target Neighborhood Hits	326	Shared Neighborhood Hits	132
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI22_HUMAN
NC score	0.853781 (rank : 39)	θ value	5.76516e-39 (rank : 35)
Query Neighborhood Hits	431	Target Neighborhood Hits	396	Shared Neighborhood Hits	145
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI50_HUMAN
NC score	0.848046 (rank : 40)	θ value	2.77131e-33 (rank : 48)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	125
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RNF39_HUMAN
NC score	0.847603 (rank : 41)	θ value	2.20605e-14 (rank : 62)
Query Neighborhood Hits	431	Target Neighborhood Hits	200	Shared Neighborhood Hits	114
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI26_HUMAN
NC score	0.842002 (rank : 42)	θ value	1.6247e-33 (rank : 47)
Query Neighborhood Hits	431	Target Neighborhood Hits	335	Shared Neighborhood Hits	125
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI35_HUMAN
NC score	0.840716 (rank : 43)	θ value	1.80048e-24 (rank : 55)
Query Neighborhood Hits	431	Target Neighborhood Hits	382	Shared Neighborhood Hits	144
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI26_MOUSE
NC score	0.838676 (rank : 44)	θ value	1.79631e-32 (rank : 49)
Query Neighborhood Hits	431	Target Neighborhood Hits	339	Shared Neighborhood Hits	123
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

BT2A2_HUMAN
NC score	0.835345 (rank : 45)	θ value	7.27602e-42 (rank : 30)
Query Neighborhood Hits	431	Target Neighborhood Hits	191	Shared Neighborhood Hits	79
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BTNL9_HUMAN
NC score	0.833710 (rank : 46)	θ value	5.96599e-36 (rank : 40)
Query Neighborhood Hits	431	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

TRI48_HUMAN
NC score	0.833459 (rank : 47)	θ value	1.68911e-14 (rank : 61)
Query Neighborhood Hits	431	Target Neighborhood Hits	192	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI30_MOUSE
NC score	0.831456 (rank : 48)	θ value	2.05525e-28 (rank : 54)
Query Neighborhood Hits	431	Target Neighborhood Hits	434	Shared Neighborhood Hits	164
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI35_MOUSE
NC score	0.829234 (rank : 49)	θ value	2.69047e-20 (rank : 56)
Query Neighborhood Hits	431	Target Neighborhood Hits	465	Shared Neighborhood Hits	172
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

BT2A1_HUMAN
NC score	0.824880 (rank : 50)	θ value	1.08726e-37 (rank : 37)
Query Neighborhood Hits	431	Target Neighborhood Hits	185	Shared Neighborhood Hits	82
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BTNL3_HUMAN
NC score	0.823639 (rank : 51)	θ value	9.52487e-34 (rank : 46)
Query Neighborhood Hits	431	Target Neighborhood Hits	143	Shared Neighborhood Hits	78
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

TRI14_MOUSE
NC score	0.822753 (rank : 52)	θ value	3.51386e-20 (rank : 57)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

BT2A3_HUMAN
NC score	0.822112 (rank : 53)	θ value	3.86705e-35 (rank : 43)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	77
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT1A1_MOUSE
NC score	0.820287 (rank : 54)	θ value	7.27602e-42 (rank : 29)
Query Neighborhood Hits	431	Target Neighborhood Hits	252	Shared Neighborhood Hits	82
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT3A3_HUMAN
NC score	0.819952 (rank : 55)	θ value	2.11701e-41 (rank : 31)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	81
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT3A1_HUMAN
NC score	0.818887 (rank : 56)	θ value	1.79215e-40 (rank : 32)
Query Neighborhood Hits	431	Target Neighborhood Hits	229	Shared Neighborhood Hits	86
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

TRI14_HUMAN
NC score	0.813484 (rank : 57)	θ value	5.07402e-19 (rank : 58)
Query Neighborhood Hits	431	Target Neighborhood Hits	143	Shared Neighborhood Hits	117
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

BT1A1_HUMAN
NC score	0.811350 (rank : 58)	θ value	1.73182e-43 (rank : 25)
Query Neighborhood Hits	431	Target Neighborhood Hits	322	Shared Neighborhood Hits	82
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BTNL8_HUMAN
NC score	0.803184 (rank : 59)	θ value	5.40856e-29 (rank : 53)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

MEFV_MOUSE
NC score	0.774427 (rank : 60)	θ value	8.35901e-139 (rank : 2)
Query Neighborhood Hits	431	Target Neighborhood Hits	236	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

BSPRY_HUMAN
NC score	0.772481 (rank : 61)	θ value	5.25075e-16 (rank : 60)
Query Neighborhood Hits	431	Target Neighborhood Hits	115	Shared Neighborhood Hits	100
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
NC score	0.758629 (rank : 62)	θ value	3.29651e-10 (rank : 64)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	101
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRI31_HUMAN
NC score	0.742271 (rank : 63)	θ value	1.92812e-18 (rank : 59)
Query Neighborhood Hits	431	Target Neighborhood Hits	299	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI12_MOUSE
NC score	0.734363 (rank : 64)	θ value	3.29651e-10 (rank : 65)
Query Neighborhood Hits	431	Target Neighborhood Hits	387	Shared Neighborhood Hits	132
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI52_HUMAN
NC score	0.721807 (rank : 65)	θ value	4.1701e-05 (rank : 88)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	98
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

SPRY4_MOUSE
NC score	0.714217 (rank : 66)	θ value	2.61198e-07 (rank : 72)
Query Neighborhood Hits	431	Target Neighborhood Hits	82	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_HUMAN
NC score	0.697450 (rank : 67)	θ value	5.81887e-07 (rank : 74)
Query Neighborhood Hits	431	Target Neighborhood Hits	79	Shared Neighborhood Hits	77
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TRI16_HUMAN
NC score	0.686361 (rank : 68)	θ value	4.16044e-13 (rank : 63)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	128
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI40_HUMAN
NC score	0.684575 (rank : 69)	θ value	2.21117e-06 (rank : 78)
Query Neighborhood Hits	431	Target Neighborhood Hits	279	Shared Neighborhood Hits	100
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI16_MOUSE
NC score	0.683627 (rank : 70)	θ value	4.30538e-10 (rank : 66)
Query Neighborhood Hits	431	Target Neighborhood Hits	196	Shared Neighborhood Hits	119
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI65_MOUSE
NC score	0.675347 (rank : 71)	θ value	1.29631e-06 (rank : 76)
Query Neighborhood Hits	431	Target Neighborhood Hits	340	Shared Neighborhood Hits	125
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_HUMAN
NC score	0.673258 (rank : 72)	θ value	0.000786445 (rank : 95)
Query Neighborhood Hits	431	Target Neighborhood Hits	330	Shared Neighborhood Hits	128
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI74_HUMAN
NC score	0.672480 (rank : 73)	θ value	3.19293e-05 (rank : 87)
Query Neighborhood Hits	431	Target Neighborhood Hits	249	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI73_HUMAN
NC score	0.671701 (rank : 74)	θ value	3.19293e-05 (rank : 86)
Query Neighborhood Hits	431	Target Neighborhood Hits	258	Shared Neighborhood Hits	109
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI25_HUMAN
NC score	0.656265 (rank : 75)	θ value	3.64472e-09 (rank : 68)
Query Neighborhood Hits	431	Target Neighborhood Hits	472	Shared Neighborhood Hits	169
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
NC score	0.642985 (rank : 76)	θ value	4.76016e-09 (rank : 69)
Query Neighborhood Hits	431	Target Neighborhood Hits	446	Shared Neighborhood Hits	162
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI13_MOUSE
NC score	0.608160 (rank : 77)	θ value	0.00035302 (rank : 90)
Query Neighborhood Hits	431	Target Neighborhood Hits	282	Shared Neighborhood Hits	114
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI13_HUMAN
NC score	0.605819 (rank : 78)	θ value	0.00102713 (rank : 96)
Query Neighborhood Hits	431	Target Neighborhood Hits	274	Shared Neighborhood Hits	109
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI18_HUMAN
NC score	0.588332 (rank : 79)	θ value	2.13673e-09 (rank : 67)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI59_MOUSE
NC score	0.585340 (rank : 80)	θ value	2.21117e-06 (rank : 79)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	117
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.582951 (rank : 81)	θ value	6.43352e-06 (rank : 81)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	130
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI18_MOUSE
NC score	0.565248 (rank : 82)	θ value	4.45536e-07 (rank : 73)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	130
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI47_MOUSE
NC score	0.556526 (rank : 83)	θ value	0.000786445 (rank : 94)
Query Neighborhood Hits	431	Target Neighborhood Hits	295	Shared Neighborhood Hits	126
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM8_MOUSE
NC score	0.553314 (rank : 84)	θ value	0.00175202 (rank : 103)
Query Neighborhood Hits	431	Target Neighborhood Hits	674	Shared Neighborhood Hits	189
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.551081 (rank : 85)	θ value	0.00134147 (rank : 102)
Query Neighborhood Hits	431	Target Neighborhood Hits	650	Shared Neighborhood Hits	190
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM1_HUMAN
NC score	0.544410 (rank : 86)	θ value	6.43352e-06 (rank : 82)
Query Neighborhood Hits	431	Target Neighborhood Hits	345	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.542714 (rank : 87)	θ value	6.43352e-06 (rank : 83)
Query Neighborhood Hits	431	Target Neighborhood Hits	361	Shared Neighborhood Hits	149
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI44_MOUSE
NC score	0.541470 (rank : 88)	θ value	0.47712 (rank : 205)
Query Neighborhood Hits	431	Target Neighborhood Hits	327	Shared Neighborhood Hits	104
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI47_HUMAN
NC score	0.538426 (rank : 89)	θ value	0.125558 (rank : 150)
Query Neighborhood Hits	431	Target Neighborhood Hits	286	Shared Neighborhood Hits	125
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI44_HUMAN
NC score	0.528484 (rank : 90)	θ value	0.279714 (rank : 179)
Query Neighborhood Hits	431	Target Neighborhood Hits	393	Shared Neighborhood Hits	116
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI63_MOUSE
NC score	0.503067 (rank : 91)	θ value	0.125558 (rank : 151)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	118
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI63_HUMAN
NC score	0.499321 (rank : 92)	θ value	0.279714 (rank : 180)
Query Neighborhood Hits	431	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI32_HUMAN
NC score	0.492250 (rank : 93)	θ value	0.0252991 (rank : 122)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	113
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.489366 (rank : 94)	θ value	0.0148317 (rank : 118)
Query Neighborhood Hits	431	Target Neighborhood Hits	271	Shared Neighborhood Hits	113
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

ZN179_HUMAN
NC score	0.487505 (rank : 95)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	431	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

TRI55_HUMAN
NC score	0.486878 (rank : 96)	θ value	0.0736092 (rank : 136)
Query Neighborhood Hits	431	Target Neighborhood Hits	292	Shared Neighborhood Hits	117
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI37_MOUSE
NC score	0.479803 (rank : 97)	θ value	0.00298849 (rank : 108)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	119
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI37_HUMAN
NC score	0.479631 (rank : 98)	θ value	0.00298849 (rank : 107)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	116
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI29_MOUSE
NC score	0.471697 (rank : 99)	θ value	0.00228821 (rank : 105)
Query Neighborhood Hits	431	Target Neighborhood Hits	306	Shared Neighborhood Hits	135
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI54_HUMAN
NC score	0.459811 (rank : 100)	θ value	0.0563607 (rank : 130)
Query Neighborhood Hits	431	Target Neighborhood Hits	209	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
NC score	0.458707 (rank : 101)	θ value	0.47712 (rank : 206)
Query Neighborhood Hits	431	Target Neighborhood Hits	197	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI29_HUMAN
NC score	0.458688 (rank : 102)	θ value	0.00134147 (rank : 101)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	127
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRIM3_MOUSE
NC score	0.446974 (rank : 103)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	431	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.440851 (rank : 104)	θ value	0.0563607 (rank : 131)
Query Neighborhood Hits	431	Target Neighborhood Hits	357	Shared Neighborhood Hits	119
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
NC score	0.434496 (rank : 105)	θ value	0.0330416 (rank : 124)
Query Neighborhood Hits	431	Target Neighborhood Hits	330	Shared Neighborhood Hits	114
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.434057 (rank : 106)	θ value	0.0736092 (rank : 137)
Query Neighborhood Hits	431	Target Neighborhood Hits	331	Shared Neighborhood Hits	114
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI46_MOUSE
NC score	0.402163 (rank : 107)	θ value	0.0431538 (rank : 127)
Query Neighborhood Hits	431	Target Neighborhood Hits	287	Shared Neighborhood Hits	126
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.400748 (rank : 108)	θ value	0.0431538 (rank : 126)
Query Neighborhood Hits	431	Target Neighborhood Hits	291	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRIM9_HUMAN
NC score	0.387461 (rank : 109)	θ value	0.00175202 (rank : 104)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI36_HUMAN
NC score	0.384670 (rank : 110)	θ value	0.000461057 (rank : 91)
Query Neighborhood Hits	431	Target Neighborhood Hits	282	Shared Neighborhood Hits	139
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

BFAR_HUMAN
NC score	0.381365 (rank : 111)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRIM9_MOUSE
NC score	0.378677 (rank : 112)	θ value	0.00102713 (rank : 98)
Query Neighborhood Hits	431	Target Neighborhood Hits	274	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI36_MOUSE
NC score	0.376502 (rank : 113)	θ value	0.00102713 (rank : 97)
Query Neighborhood Hits	431	Target Neighborhood Hits	266	Shared Neighborhood Hits	135
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

BFAR_MOUSE
NC score	0.373031 (rank : 114)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	431	Target Neighborhood Hits	232	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_HUMAN
NC score	0.367955 (rank : 115)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	431	Target Neighborhood Hits	381	Shared Neighborhood Hits	105
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
NC score	0.364140 (rank : 116)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	431	Target Neighborhood Hits	436	Shared Neighborhood Hits	111
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN168_HUMAN
NC score	0.349915 (rank : 117)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	431	Target Neighborhood Hits	370	Shared Neighborhood Hits	113
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ZN313_MOUSE
NC score	0.349726 (rank : 118)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	431	Target Neighborhood Hits	273	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

PEX10_HUMAN
NC score	0.344906 (rank : 119)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	71
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

ZN313_HUMAN
NC score	0.341140 (rank : 120)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

RN168_MOUSE
NC score	0.334377 (rank : 121)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	431	Target Neighborhood Hits	440	Shared Neighborhood Hits	138
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN125_MOUSE
NC score	0.332846 (rank : 122)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	431	Target Neighborhood Hits	220	Shared Neighborhood Hits	74
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN166_HUMAN
NC score	0.329284 (rank : 123)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	81
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
NC score	0.323171 (rank : 124)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	431	Target Neighborhood Hits	248	Shared Neighborhood Hits	86
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN125_HUMAN
NC score	0.322675 (rank : 125)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	431	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RNF8_MOUSE
NC score	0.316956 (rank : 126)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	431	Target Neighborhood Hits	618	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRI56_MOUSE
NC score	0.312911 (rank : 127)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	99
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.312844 (rank : 128)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	431	Target Neighborhood Hits	339	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

RNF8_HUMAN
NC score	0.303714 (rank : 129)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	431	Target Neighborhood Hits	622	Shared Neighborhood Hits	155
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

BT3A2_HUMAN
NC score	0.293140 (rank : 130)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

RN169_HUMAN
NC score	0.286345 (rank : 131)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	431	Target Neighborhood Hits	203	Shared Neighborhood Hits	75
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

BTNL1_MOUSE
NC score	0.283832 (rank : 132)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	431	Target Neighborhood Hits	151	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TST0, O70356	Gene names	Btnl1, Btnl3, Gm316, Ng10
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 1 precursor.

RAG1_HUMAN
NC score	0.282664 (rank : 133)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	431	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN183_HUMAN
NC score	0.280206 (rank : 134)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	431	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

BTNL2_HUMAN
NC score	0.273607 (rank : 135)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	431	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

RAG1_MOUSE
NC score	0.272981 (rank : 136)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	431	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RING1_HUMAN
NC score	0.269583 (rank : 137)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	83
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

MOG_HUMAN
NC score	0.264645 (rank : 138)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	431	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q16653, O00713, O00714, O00715, Q13054, Q13055, Q14855, Q92891, Q92892, Q92893, Q92894, Q92895, Q93053, Q96KU9, Q96KV0, Q96KV1, Q99605	Gene names	MOG
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

RING1_MOUSE
NC score	0.264161 (rank : 139)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	431	Target Neighborhood Hits	220	Shared Neighborhood Hits	84
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

MOG_MOUSE
NC score	0.264111 (rank : 140)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	431	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q61885, P70364, Q62003	Gene names	Mog
Domain Architecture
Description	Myelin-oligodendrocyte glycoprotein precursor.

TRI42_MOUSE
NC score	0.263516 (rank : 141)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	431	Target Neighborhood Hits	316	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
NC score	0.263283 (rank : 142)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	431	Target Neighborhood Hits	283	Shared Neighborhood Hits	90
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RN185_MOUSE
NC score	0.248251 (rank : 143)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	431	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_HUMAN
NC score	0.248089 (rank : 144)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RING2_HUMAN
NC score	0.244486 (rank : 145)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	431	Target Neighborhood Hits	201	Shared Neighborhood Hits	76
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
NC score	0.244465 (rank : 146)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RNF41_MOUSE
NC score	0.243866 (rank : 147)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	431	Target Neighborhood Hits	224	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.243714 (rank : 148)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	431	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF5_HUMAN
NC score	0.242052 (rank : 149)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
NC score	0.240919 (rank : 150)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF4_HUMAN
NC score	0.240289 (rank : 151)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	431	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.233000 (rank : 152)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	431	Target Neighborhood Hits	212	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RN183_MOUSE
NC score	0.231939 (rank : 153)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	431	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TIF1G_HUMAN
NC score	0.227348 (rank : 154)	θ value	0.279714 (rank : 176)
Query Neighborhood Hits	431	Target Neighborhood Hits	410	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.223822 (rank : 155)	θ value	0.279714 (rank : 177)
Query Neighborhood Hits	431	Target Neighborhood Hits	498	Shared Neighborhood Hits	117
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRAF6_MOUSE
NC score	0.223636 (rank : 156)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	84
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

BIRC7_HUMAN
NC score	0.223521 (rank : 157)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	431	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

PML_HUMAN
NC score	0.223290 (rank : 158)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	431	Target Neighborhood Hits	248	Shared Neighborhood Hits	98
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

CHFR_HUMAN
NC score	0.223129 (rank : 159)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.216216 (rank : 160)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	431	Target Neighborhood Hits	264	Shared Neighborhood Hits	76
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

TRAF6_HUMAN
NC score	0.215512 (rank : 161)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

RAD18_MOUSE
NC score	0.214794 (rank : 162)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	431	Target Neighborhood Hits	230	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN146_HUMAN
NC score	0.214757 (rank : 163)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	431	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

DTX3_MOUSE
NC score	0.214667 (rank : 164)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	431	Target Neighborhood Hits	202	Shared Neighborhood Hits	71
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

RN146_MOUSE
NC score	0.213439 (rank : 165)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

DTX3_HUMAN
NC score	0.207771 (rank : 166)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	431	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

TRI45_HUMAN
NC score	0.206178 (rank : 167)	θ value	1.38821 (rank : 271)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	91
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TIF1B_HUMAN
NC score	0.204511 (rank : 168)	θ value	0.00298849 (rank : 106)
Query Neighborhood Hits	431	Target Neighborhood Hits	312	Shared Neighborhood Hits	105
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

UHRF2_HUMAN
NC score	0.202040 (rank : 169)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	431	Target Neighborhood Hits	269	Shared Neighborhood Hits	87
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RN141_HUMAN
NC score	0.199101 (rank : 170)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	431	Target Neighborhood Hits	199	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

SMRA3_HUMAN
NC score	0.198938 (rank : 171)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	431	Target Neighborhood Hits	265	Shared Neighborhood Hits	84
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TIF1B_MOUSE
NC score	0.197874 (rank : 172)	θ value	0.0113563 (rank : 115)
Query Neighborhood Hits	431	Target Neighborhood Hits	276	Shared Neighborhood Hits	96
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

RN141_MOUSE
NC score	0.197650 (rank : 173)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	431	Target Neighborhood Hits	200	Shared Neighborhood Hits	74
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

UHRF2_MOUSE
NC score	0.197591 (rank : 174)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	431	Target Neighborhood Hits	275	Shared Neighborhood Hits	88
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

TRI45_MOUSE
NC score	0.195867 (rank : 175)	θ value	0.163984 (rank : 158)
Query Neighborhood Hits	431	Target Neighborhood Hits	155	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

PML_MOUSE
NC score	0.194079 (rank : 176)	θ value	2.36792 (rank : 311)
Query Neighborhood Hits	431	Target Neighborhood Hits	246	Shared Neighborhood Hits	94
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RFWD2_HUMAN
NC score	0.194037 (rank : 177)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	431	Target Neighborhood Hits	518	Shared Neighborhood Hits	92
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RAD18_HUMAN
NC score	0.193208 (rank : 178)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	431	Target Neighborhood Hits	284	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RFWD2_MOUSE
NC score	0.193157 (rank : 179)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	431	Target Neighborhood Hits	535	Shared Neighborhood Hits	96
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

CM007_MOUSE
NC score	0.185704 (rank : 180)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	431	Target Neighborhood Hits	416	Shared Neighborhood Hits	103
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

SMRA3_MOUSE
NC score	0.185416 (rank : 181)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	431	Target Neighborhood Hits	267	Shared Neighborhood Hits	79
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

R113B_HUMAN
NC score	0.169800 (rank : 182)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	431	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

CM007_HUMAN
NC score	0.165378 (rank : 183)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	431	Target Neighborhood Hits	422	Shared Neighborhood Hits	105
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

LNX1_MOUSE
NC score	0.164548 (rank : 184)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	431	Target Neighborhood Hits	377	Shared Neighborhood Hits	87
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

UHRF1_MOUSE
NC score	0.163013 (rank : 185)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PCGF6_MOUSE
NC score	0.162819 (rank : 186)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	60
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRAF5_MOUSE
NC score	0.161336 (rank : 187)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	431	Target Neighborhood Hits	355	Shared Neighborhood Hits	116
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

ASC_MOUSE
NC score	0.161223 (rank : 188)	θ value	2.36244e-08 (rank : 70)
Query Neighborhood Hits	431	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

LNX1_HUMAN
NC score	0.160726 (rank : 189)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	431	Target Neighborhood Hits	379	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TIF1A_HUMAN
NC score	0.159611 (rank : 190)	θ value	0.365318 (rank : 193)
Query Neighborhood Hits	431	Target Neighborhood Hits	327	Shared Neighborhood Hits	96
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

R113A_HUMAN
NC score	0.158945 (rank : 191)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	63
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

PCGF6_HUMAN
NC score	0.157366 (rank : 192)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	431	Target Neighborhood Hits	178	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

LNX2_MOUSE
NC score	0.155456 (rank : 193)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	91
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

CD276_MOUSE
NC score	0.153916 (rank : 194)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	431	Target Neighborhood Hits	243	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

LNX2_HUMAN
NC score	0.153818 (rank : 195)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	431	Target Neighborhood Hits	389	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

UHRF1_HUMAN
NC score	0.153319 (rank : 196)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	431	Target Neighborhood Hits	272	Shared Neighborhood Hits	82
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RC3H1_MOUSE
NC score	0.149645 (rank : 197)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	431	Target Neighborhood Hits	244	Shared Neighborhood Hits	81
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRAIP_HUMAN
NC score	0.146191 (rank : 198)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	431	Target Neighborhood Hits	780	Shared Neighborhood Hits	146
SwissProt Accessions	Q9BWF2, O00467	Gene names	TRAIP, TRIP
Domain Architecture
Description	TRAF-interacting protein.

ASC_HUMAN
NC score	0.145707 (rank : 199)	θ value	2.21117e-06 (rank : 77)
Query Neighborhood Hits	431	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

RC3H1_HUMAN
NC score	0.145234 (rank : 200)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	95
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

TRAF5_HUMAN
NC score	0.143145 (rank : 201)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	431	Target Neighborhood Hits	396	Shared Neighborhood Hits	126
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

CD276_HUMAN
NC score	0.138767 (rank : 202)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	12
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

PCGF4_MOUSE
NC score	0.138270 (rank : 203)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	50
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PCGF4_HUMAN
NC score	0.137507 (rank : 204)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

TIF1A_MOUSE
NC score	0.136635 (rank : 205)	θ value	0.279714 (rank : 175)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	89
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

ICOSL_HUMAN
NC score	0.134116 (rank : 206)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	431	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	O75144, Q9HD18, Q9NRQ1	Gene names	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD275 antigen).

PZRN3_MOUSE
NC score	0.133104 (rank : 207)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	431	Target Neighborhood Hits	447	Shared Neighborhood Hits	95
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RBBP6_MOUSE
NC score	0.131605 (rank : 208)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	431	Target Neighborhood Hits	1014	Shared Neighborhood Hits	125
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PZRN4_HUMAN
NC score	0.131187 (rank : 209)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	431	Target Neighborhood Hits	438	Shared Neighborhood Hits	92
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAIP_MOUSE
NC score	0.131094 (rank : 210)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	431	Target Neighborhood Hits	745	Shared Neighborhood Hits	142
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

PZRN3_HUMAN
NC score	0.130651 (rank : 211)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	431	Target Neighborhood Hits	461	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PCGF2_HUMAN
NC score	0.128573 (rank : 212)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	55
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.128378 (rank : 213)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	54
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

TRAF7_HUMAN
NC score	0.126048 (rank : 214)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	431	Target Neighborhood Hits	482	Shared Neighborhood Hits	90
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

PDL1_MOUSE
NC score	0.125841 (rank : 215)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	431	Target Neighborhood Hits	168	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

TRAF7_MOUSE
NC score	0.125476 (rank : 216)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	88
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRAF4_HUMAN
NC score	0.125255 (rank : 217)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	431	Target Neighborhood Hits	373	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

NAL10_HUMAN
NC score	0.123837 (rank : 218)	θ value	3.08544e-08 (rank : 71)
Query Neighborhood Hits	431	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

RBBP6_HUMAN
NC score	0.123583 (rank : 219)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	431	Target Neighborhood Hits	1135	Shared Neighborhood Hits	151
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

MAT1_HUMAN
NC score	0.119053 (rank : 220)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	431	Target Neighborhood Hits	179	Shared Neighborhood Hits	67
SwissProt Accessions	P51948, Q15817	Gene names	MNAT1, CAP35, MAT1, RNF66
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35) (Cyclin G1-interacting protein) (RING finger protein 66).

MAT1_MOUSE
NC score	0.118979 (rank : 221)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	431	Target Neighborhood Hits	217	Shared Neighborhood Hits	74
SwissProt Accessions	P51949, Q3TZP0, Q9D8A0, Q9D8D2	Gene names	Mnat1, Mat1
Domain Architecture
Description	CDK-activating kinase assembly factor MAT1 (RING finger protein MAT1) (Menage a trois) (CDK7/cyclin H assembly factor) (p36) (p35).

HHLA2_HUMAN
NC score	0.118912 (rank : 222)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	431	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

CD86_HUMAN
NC score	0.116863 (rank : 223)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	431	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42081, Q13655, Q7M4L5	Gene names	CD86, CD28LG2
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (CTLA-4 counter-receptor B7.2) (B70) (FUN-1) (BU63).

TRAF2_MOUSE
NC score	0.115993 (rank : 224)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	431	Target Neighborhood Hits	394	Shared Neighborhood Hits	84
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

RN152_MOUSE
NC score	0.115900 (rank : 225)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	431	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TOPRS_MOUSE
NC score	0.115138 (rank : 226)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	431	Target Neighborhood Hits	263	Shared Neighborhood Hits	54
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RN152_HUMAN
NC score	0.114166 (rank : 227)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	431	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TRAF2_HUMAN
NC score	0.113307 (rank : 228)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	431	Target Neighborhood Hits	402	Shared Neighborhood Hits	87
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

NHLC1_MOUSE
NC score	0.112822 (rank : 229)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	431	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TOPRS_HUMAN
NC score	0.112201 (rank : 230)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	431	Target Neighborhood Hits	286	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

CD86_MOUSE
NC score	0.111294 (rank : 231)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	431	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	P42082	Gene names	Cd86
Domain Architecture
Description	T-lymphocyte activation antigen CD86 precursor (Activation B7-2 antigen) (Early T-cell costimulatory molecule 1) (ETC-1).

NHLC1_HUMAN
NC score	0.110996 (rank : 232)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	431	Target Neighborhood Hits	91	Shared Neighborhood Hits	38
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

ICOSL_MOUSE
NC score	0.107608 (rank : 233)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	431	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JHJ8	Gene names	Icoslg, B7h2, B7rp1, Icosl
Domain Architecture
Description	ICOS ligand precursor (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD275 antigen).

AMFR2_HUMAN
NC score	0.106249 (rank : 234)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
NC score	0.105890 (rank : 235)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	431	Target Neighborhood Hits	208	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

CIAS1_MOUSE
NC score	0.105037 (rank : 236)	θ value	4.92598e-06 (rank : 80)
Query Neighborhood Hits	431	Target Neighborhood Hits	67	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL10_MOUSE
NC score	0.104633 (rank : 237)	θ value	0.00134147 (rank : 100)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

CIAS1_HUMAN
NC score	0.104522 (rank : 238)	θ value	9.92553e-07 (rank : 75)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

BARD1_HUMAN
NC score	0.104363 (rank : 239)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	431	Target Neighborhood Hits	427	Shared Neighborhood Hits	64
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PDL2_HUMAN
NC score	0.104290 (rank : 240)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	431	Target Neighborhood Hits	114	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

TRAF3_MOUSE
NC score	0.103862 (rank : 241)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	431	Target Neighborhood Hits	476	Shared Neighborhood Hits	130
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

MNAB_HUMAN
NC score	0.102548 (rank : 242)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	431	Target Neighborhood Hits	196	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

BARD1_MOUSE
NC score	0.101624 (rank : 243)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	431	Target Neighborhood Hits	411	Shared Neighborhood Hits	62
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MNAB_MOUSE
NC score	0.101267 (rank : 244)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	431	Target Neighborhood Hits	231	Shared Neighborhood Hits	74
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

NAL12_HUMAN
NC score	0.101264 (rank : 245)	θ value	1.09739e-05 (rank : 84)
Query Neighborhood Hits	431	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP6_HUMAN
NC score	0.100567 (rank : 246)	θ value	0.000602161 (rank : 92)
Query Neighborhood Hits	431	Target Neighborhood Hits	52	Shared Neighborhood Hits	16
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

PDL2_MOUSE
NC score	0.097861 (rank : 247)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	431	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

NALP4_HUMAN
NC score	0.097431 (rank : 248)	θ value	1.09739e-05 (rank : 85)
Query Neighborhood Hits	431	Target Neighborhood Hits	81	Shared Neighborhood Hits	17
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

TRAF3_HUMAN
NC score	0.096420 (rank : 249)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	431	Target Neighborhood Hits	463	Shared Neighborhood Hits	123
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

PDL1_HUMAN
NC score	0.095158 (rank : 250)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

ARD1_MOUSE
NC score	0.094746 (rank : 251)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	431	Target Neighborhood Hits	573	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

ARD1_HUMAN
NC score	0.093209 (rank : 252)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	431	Target Neighborhood Hits	621	Shared Neighborhood Hits	75
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

BIRC8_HUMAN
NC score	0.092628 (rank : 253)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	431	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

CBL_HUMAN
NC score	0.091855 (rank : 254)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	431	Target Neighborhood Hits	353	Shared Neighborhood Hits	74
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

BRE1B_HUMAN
NC score	0.091658 (rank : 255)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	431	Target Neighborhood Hits	1040	Shared Neighborhood Hits	193
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

RNF32_HUMAN
NC score	0.090476 (rank : 256)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	431	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

CBL_MOUSE
NC score	0.090391 (rank : 257)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	431	Target Neighborhood Hits	426	Shared Neighborhood Hits	85
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

BRE1B_MOUSE
NC score	0.090340 (rank : 258)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	431	Target Neighborhood Hits	970	Shared Neighborhood Hits	189
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

NALP6_MOUSE
NC score	0.089046 (rank : 259)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	431	Target Neighborhood Hits	55	Shared Neighborhood Hits	15
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

CBLB_MOUSE
NC score	0.087368 (rank : 260)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	431	Target Neighborhood Hits	277	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

NAL14_HUMAN
NC score	0.086618 (rank : 261)	θ value	9.29e-05 (rank : 89)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	14
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP2_HUMAN
NC score	0.086446 (rank : 262)	θ value	0.00390308 (rank : 109)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

CBLB_HUMAN
NC score	0.085824 (rank : 263)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	431	Target Neighborhood Hits	261	Shared Neighborhood Hits	67
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

NALP5_HUMAN
NC score	0.085553 (rank : 264)	θ value	0.0148317 (rank : 116)
Query Neighborhood Hits	431	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

UB7I3_MOUSE
NC score	0.084220 (rank : 265)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	431	Target Neighborhood Hits	131	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

BRAP_HUMAN
NC score	0.083333 (rank : 266)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	431	Target Neighborhood Hits	560	Shared Neighborhood Hits	111
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

NALP7_HUMAN
NC score	0.081250 (rank : 267)	θ value	1.06291 (rank : 244)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

RNF32_MOUSE
NC score	0.081128 (rank : 268)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RNF34_MOUSE
NC score	0.080847 (rank : 269)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	431	Target Neighborhood Hits	160	Shared Neighborhood Hits	33
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

CNOT4_HUMAN
NC score	0.080605 (rank : 270)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	431	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RNF34_HUMAN
NC score	0.079550 (rank : 271)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	431	Target Neighborhood Hits	153	Shared Neighborhood Hits	32
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

NALP1_HUMAN
NC score	0.079412 (rank : 272)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	431	Target Neighborhood Hits	138	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

CNOT4_MOUSE
NC score	0.078500 (rank : 273)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	431	Target Neighborhood Hits	277	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

GOGA4_MOUSE
NC score	0.078262 (rank : 274)	θ value	0.125558 (rank : 144)
Query Neighborhood Hits	431	Target Neighborhood Hits	1939	Shared Neighborhood Hits	209
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CBLC_MOUSE
NC score	0.078042 (rank : 275)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	431	Target Neighborhood Hits	186	Shared Neighborhood Hits	50
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RKHD1_HUMAN
NC score	0.076702 (rank : 276)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

BIRC3_HUMAN
NC score	0.076514 (rank : 277)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	431	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

CP250_HUMAN
NC score	0.076207 (rank : 278)	θ value	3.0926 (rank : 320)
Query Neighborhood Hits	431	Target Neighborhood Hits	1805	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

BIRC2_HUMAN
NC score	0.075293 (rank : 279)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	431	Target Neighborhood Hits	142	Shared Neighborhood Hits	49
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

GCC2_MOUSE
NC score	0.075015 (rank : 280)	θ value	0.62314 (rank : 211)
Query Neighborhood Hits	431	Target Neighborhood Hits	1619	Shared Neighborhood Hits	186
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

TRI66_MOUSE
NC score	0.073795 (rank : 281)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	431	Target Neighborhood Hits	491	Shared Neighborhood Hits	98
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

DTX3L_HUMAN
NC score	0.073453 (rank : 282)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	431	Target Neighborhood Hits	187	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

BRE1A_HUMAN
NC score	0.073077 (rank : 283)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	431	Target Neighborhood Hits	1071	Shared Neighborhood Hits	167
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CBLC_HUMAN
NC score	0.072696 (rank : 284)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	431	Target Neighborhood Hits	173	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

PCNT_HUMAN
NC score	0.072630 (rank : 285)	θ value	1.81305 (rank : 287)
Query Neighborhood Hits	431	Target Neighborhood Hits	1551	Shared Neighborhood Hits	187
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

GOGB1_HUMAN
NC score	0.072498 (rank : 286)	θ value	0.47712 (rank : 197)
Query Neighborhood Hits	431	Target Neighborhood Hits	2297	Shared Neighborhood Hits	212
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NALP5_MOUSE
NC score	0.072470 (rank : 287)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	431	Target Neighborhood Hits	560	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NAL11_HUMAN
NC score	0.072425 (rank : 288)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	431	Target Neighborhood Hits	66	Shared Neighborhood Hits	11
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL13_HUMAN
NC score	0.072195 (rank : 289)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	431	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

BRE1A_MOUSE
NC score	0.072169 (rank : 290)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	431	Target Neighborhood Hits	1025	Shared Neighborhood Hits	167
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CCD46_HUMAN
NC score	0.072085 (rank : 291)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	431	Target Neighborhood Hits	1430	Shared Neighborhood Hits	188
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CF060_HUMAN
NC score	0.071540 (rank : 292)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	431	Target Neighborhood Hits	1270	Shared Neighborhood Hits	170
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

AZI1_MOUSE
NC score	0.071447 (rank : 293)	θ value	1.06291 (rank : 237)
Query Neighborhood Hits	431	Target Neighborhood Hits	990	Shared Neighborhood Hits	150
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

GOGA4_HUMAN
NC score	0.071118 (rank : 294)	θ value	0.0330416 (rank : 123)
Query Neighborhood Hits	431	Target Neighborhood Hits	2034	Shared Neighborhood Hits	200
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

BIRC2_MOUSE
NC score	0.070638 (rank : 295)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	41
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

CD80_MOUSE
NC score	0.070512 (rank : 296)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	431	Target Neighborhood Hits	136	Shared Neighborhood Hits	11
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

RN123_MOUSE
NC score	0.070491 (rank : 297)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	431	Target Neighborhood Hits	174	Shared Neighborhood Hits	53
SwissProt Accessions	Q5XPI3, Q6PGE0	Gene names	Rnf123, Kpc1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

TRI66_HUMAN
NC score	0.070236 (rank : 298)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	431	Target Neighborhood Hits	479	Shared Neighborhood Hits	89
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RN123_HUMAN
NC score	0.069705 (rank : 299)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	431	Target Neighborhood Hits	175	Shared Neighborhood Hits	52
SwissProt Accessions	Q5XPI4, Q5I022, Q6PFW4, Q71RH0, Q8IW18, Q9H0M8, Q9H5L8, Q9H9T2	Gene names	RNF123, KPC1
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase subunit KPC1 (EC 6.3.2.-) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123).

CENPF_HUMAN
NC score	0.068803 (rank : 300)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	431	Target Neighborhood Hits	1932	Shared Neighborhood Hits	204
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

BRAP_MOUSE
NC score	0.068385 (rank : 301)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	431	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

AZI1_HUMAN
NC score	0.068267 (rank : 302)	θ value	1.81305 (rank : 272)
Query Neighborhood Hits	431	Target Neighborhood Hits	1000	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

UB7I3_HUMAN
NC score	0.068252 (rank : 303)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	431	Target Neighborhood Hits	136	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

CENPE_HUMAN
NC score	0.067988 (rank : 304)	θ value	0.0252991 (rank : 121)
Query Neighborhood Hits	431	Target Neighborhood Hits	2060	Shared Neighborhood Hits	194
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD41_MOUSE
NC score	0.067978 (rank : 305)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	431	Target Neighborhood Hits	1399	Shared Neighborhood Hits	175
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

RBP24_HUMAN
NC score	0.067837 (rank : 306)	θ value	1.06291 (rank : 247)
Query Neighborhood Hits	431	Target Neighborhood Hits	1559	Shared Neighborhood Hits	184
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.067783 (rank : 307)	θ value	1.06291 (rank : 240)
Query Neighborhood Hits	431	Target Neighborhood Hits	1558	Shared Neighborhood Hits	185
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC1_HUMAN
NC score	0.067513 (rank : 308)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	431	Target Neighborhood Hits	887	Shared Neighborhood Hits	142
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CCD46_MOUSE
NC score	0.066744 (rank : 309)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	169
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

LRSM1_HUMAN
NC score	0.066445 (rank : 310)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	431	Target Neighborhood Hits	1078	Shared Neighborhood Hits	155
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

TRHY_HUMAN
NC score	0.065974 (rank : 311)	θ value	0.62314 (rank : 216)
Query Neighborhood Hits	431	Target Neighborhood Hits	1385	Shared Neighborhood Hits	154
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CT2NL_HUMAN
NC score	0.065950 (rank : 312)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	431	Target Neighborhood Hits	1059	Shared Neighborhood Hits	152
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NIN_HUMAN
NC score	0.065936 (rank : 313)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	431	Target Neighborhood Hits	1416	Shared Neighborhood Hits	166
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

INCE_HUMAN
NC score	0.065800 (rank : 314)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	431	Target Neighborhood Hits	978	Shared Neighborhood Hits	138
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SYCP1_MOUSE
NC score	0.065331 (rank : 315)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	431	Target Neighborhood Hits	1456	Shared Neighborhood Hits	177
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

NUMA1_HUMAN
NC score	0.065215 (rank : 316)	θ value	4.03905 (rank : 345)
Query Neighborhood Hits	431	Target Neighborhood Hits	1523	Shared Neighborhood Hits	179
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

AKAP9_HUMAN
NC score	0.063659 (rank : 317)	θ value	0.0193708 (rank : 119)
Query Neighborhood Hits	431	Target Neighborhood Hits	1710	Shared Neighborhood Hits	168
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CNTRB_MOUSE
NC score	0.063405 (rank : 318)	θ value	1.81305 (rank : 275)
Query Neighborhood Hits	431	Target Neighborhood Hits	1029	Shared Neighborhood Hits	150
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

FLIP1_MOUSE
NC score	0.062782 (rank : 319)	θ value	2.36792 (rank : 300)
Query Neighborhood Hits	431	Target Neighborhood Hits	1176	Shared Neighborhood Hits	160
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CCD41_HUMAN
NC score	0.062588 (rank : 320)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	431	Target Neighborhood Hits	1139	Shared Neighborhood Hits	156
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

NIN_MOUSE
NC score	0.062547 (rank : 321)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	431	Target Neighborhood Hits	1376	Shared Neighborhood Hits	169
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

MGRN1_MOUSE
NC score	0.062453 (rank : 322)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	431	Target Neighborhood Hits	149	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

CP250_MOUSE
NC score	0.062452 (rank : 323)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	431	Target Neighborhood Hits	1583	Shared Neighborhood Hits	184
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA3_HUMAN
NC score	0.062101 (rank : 324)	θ value	0.47712 (rank : 196)
Query Neighborhood Hits	431	Target Neighborhood Hits	1317	Shared Neighborhood Hits	166
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

TPR_HUMAN
NC score	0.062068 (rank : 325)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	431	Target Neighborhood Hits	1921	Shared Neighborhood Hits	190
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

RBCC1_MOUSE
NC score	0.062035 (rank : 326)	θ value	0.365318 (rank : 188)
Query Neighborhood Hits	431	Target Neighborhood Hits	1048	Shared Neighborhood Hits	151
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MGRN1_HUMAN
NC score	0.061740 (rank : 327)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	431	Target Neighborhood Hits	192	Shared Neighborhood Hits	43
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

ZSWM2_HUMAN
NC score	0.061287 (rank : 328)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	431	Target Neighborhood Hits	151	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

SM1L2_HUMAN
NC score	0.061203 (rank : 329)	θ value	0.125558 (rank : 148)
Query Neighborhood Hits	431	Target Neighborhood Hits	1019	Shared Neighborhood Hits	144
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC1A_MOUSE
NC score	0.061007 (rank : 330)	θ value	0.365318 (rank : 192)
Query Neighborhood Hits	431	Target Neighborhood Hits	1384	Shared Neighborhood Hits	155
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

PJA1_HUMAN
NC score	0.060940 (rank : 331)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	431	Target Neighborhood Hits	159	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NG27, Q8NG28, Q9HAC1	Gene names	PJA1, RNF70
Domain Architecture
Description	Ubiquitin protein ligase Praja1 (EC 6.3.2.-) (RING finger protein 70).

RABE1_MOUSE
NC score	0.060599 (rank : 332)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	431	Target Neighborhood Hits	1105	Shared Neighborhood Hits	160
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

SMC1A_HUMAN
NC score	0.060561 (rank : 333)	θ value	0.365318 (rank : 191)
Query Neighborhood Hits	431	Target Neighborhood Hits	1346	Shared Neighborhood Hits	150
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

FLIP1_HUMAN
NC score	0.060534 (rank : 334)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	168
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FSD1L_MOUSE
NC score	0.060498 (rank : 335)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	431	Target Neighborhood Hits	78	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

TARA_MOUSE
NC score	0.060420 (rank : 336)	θ value	0.0563607 (rank : 129)
Query Neighborhood Hits	431	Target Neighborhood Hits	1133	Shared Neighborhood Hits	156
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CE290_HUMAN
NC score	0.060371 (rank : 337)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	431	Target Neighborhood Hits	1553	Shared Neighborhood Hits	177
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MY18A_HUMAN
NC score	0.060370 (rank : 338)	θ value	1.81305 (rank : 282)
Query Neighborhood Hits	431	Target Neighborhood Hits	1929	Shared Neighborhood Hits	189
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

REST_HUMAN
NC score	0.060133 (rank : 339)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	431	Target Neighborhood Hits	1605	Shared Neighborhood Hits	175
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RFIP3_HUMAN
NC score	0.060047 (rank : 340)	θ value	0.47712 (rank : 203)
Query Neighborhood Hits	431	Target Neighborhood Hits	1055	Shared Neighborhood Hits	149
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

NEST_HUMAN
NC score	0.059773 (rank : 341)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	431	Target Neighborhood Hits	1305	Shared Neighborhood Hits	169
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

EEA1_HUMAN
NC score	0.059602 (rank : 342)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	431	Target Neighborhood Hits	1796	Shared Neighborhood Hits	185
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGA1_HUMAN
NC score	0.059598 (rank : 343)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	431	Target Neighborhood Hits	1222	Shared Neighborhood Hits	163
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

LRC45_MOUSE
NC score	0.059535 (rank : 344)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	431	Target Neighborhood Hits	959	Shared Neighborhood Hits	145
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RABE1_HUMAN
NC score	0.059495 (rank : 345)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	431	Target Neighborhood Hits	1104	Shared Neighborhood Hits	156
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

MKRN2_MOUSE
NC score	0.059365 (rank : 346)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	431	Target Neighborhood Hits	130	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ERV1, Q9D0L9	Gene names	Mkrn2
Domain Architecture
Description	Makorin-2.

CT2NL_MOUSE
NC score	0.059276 (rank : 347)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	431	Target Neighborhood Hits	902	Shared Neighborhood Hits	143
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GCC1_MOUSE
NC score	0.059183 (rank : 348)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	431	Target Neighborhood Hits	777	Shared Neighborhood Hits	131
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

MKRN2_HUMAN
NC score	0.059041 (rank : 349)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H000, Q8N391, Q96BD4, Q9BUY2, Q9NRY1	Gene names	MKRN2, RNF62
Domain Architecture
Description	Makorin-2 (RING finger protein 62).

TRIPB_HUMAN
NC score	0.059031 (rank : 350)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	431	Target Neighborhood Hits	1587	Shared Neighborhood Hits	173
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TRAF4_MOUSE
NC score	0.058977 (rank : 351)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	431	Target Neighborhood Hits	338	Shared Neighborhood Hits	48
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

T3JAM_HUMAN
NC score	0.058706 (rank : 352)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	431	Target Neighborhood Hits	533	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

BIRC3_MOUSE
NC score	0.057893 (rank : 353)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	431	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

PCNT_MOUSE
NC score	0.057858 (rank : 354)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	431	Target Neighborhood Hits	1207	Shared Neighborhood Hits	165
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

SMC2_HUMAN
NC score	0.057785 (rank : 355)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	431	Target Neighborhood Hits	1405	Shared Neighborhood Hits	160
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

NDE1_HUMAN
NC score	0.057716 (rank : 356)	θ value	0.62314 (rank : 213)
Query Neighborhood Hits	431	Target Neighborhood Hits	823	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

CING_MOUSE
NC score	0.057632 (rank : 357)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	431	Target Neighborhood Hits	1432	Shared Neighborhood Hits	170
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

INCE_MOUSE
NC score	0.057540 (rank : 358)	θ value	1.06291 (rank : 241)
Query Neighborhood Hits	431	Target Neighborhood Hits	903	Shared Neighborhood Hits	131
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

GOGA3_MOUSE
NC score	0.057507 (rank : 359)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	431	Target Neighborhood Hits	1437	Shared Neighborhood Hits	171
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CASP_MOUSE
NC score	0.057385 (rank : 360)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	431	Target Neighborhood Hits	1152	Shared Neighborhood Hits	154
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.057363 (rank : 361)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	431	Target Neighborhood Hits	1131	Shared Neighborhood Hits	156
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

SDCG8_HUMAN
NC score	0.057309 (rank : 362)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	431	Target Neighborhood Hits	1002	Shared Neighborhood Hits	146
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

CUTL1_HUMAN
NC score	0.057294 (rank : 363)	θ value	0.279714 (rank : 169)
Query Neighborhood Hits	431	Target Neighborhood Hits	1574	Shared Neighborhood Hits	175
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

RFFL_HUMAN
NC score	0.057260 (rank : 364)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	431	Target Neighborhood Hits	175	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

CN145_MOUSE
NC score	0.057236 (rank : 365)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	431	Target Neighborhood Hits	916	Shared Neighborhood Hits	136
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

MRIP_HUMAN
NC score	0.057219 (rank : 366)	θ value	0.279714 (rank : 172)
Query Neighborhood Hits	431	Target Neighborhood Hits	578	Shared Neighborhood Hits	96
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

DYNA_HUMAN
NC score	0.057048 (rank : 367)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	431	Target Neighborhood Hits	1194	Shared Neighborhood Hits	163
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MECP2_MOUSE
NC score	0.057026 (rank : 368)	θ value	0.000786445 (rank : 93)
Query Neighborhood Hits	431	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

MIB1_HUMAN
NC score	0.056958 (rank : 369)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	57
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.056955 (rank : 370)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	431	Target Neighborhood Hits	471	Shared Neighborhood Hits	57
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

RBCC1_HUMAN
NC score	0.056817 (rank : 371)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	431	Target Neighborhood Hits	1023	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CT096_HUMAN
NC score	0.056702 (rank : 372)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	431	Target Neighborhood Hits	438	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NUD7, Q8N840, Q8NAX5	Gene names	C20orf96
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf96.

MY18A_MOUSE
NC score	0.056630 (rank : 373)	θ value	1.38821 (rank : 268)
Query Neighborhood Hits	431	Target Neighborhood Hits	1989	Shared Neighborhood Hits	182
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MRIP_MOUSE
NC score	0.056597 (rank : 374)	θ value	0.279714 (rank : 173)
Query Neighborhood Hits	431	Target Neighborhood Hits	569	Shared Neighborhood Hits	92
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

UACA_HUMAN
NC score	0.056489 (rank : 375)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	431	Target Neighborhood Hits	1622	Shared Neighborhood Hits	176
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

MYH11_HUMAN
NC score	0.056449 (rank : 376)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	431	Target Neighborhood Hits	1806	Shared Neighborhood Hits	194
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CXAR_HUMAN
NC score	0.056420 (rank : 377)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	431	Target Neighborhood Hits	245	Shared Neighborhood Hits	10
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

SDCG8_MOUSE
NC score	0.056342 (rank : 378)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	431	Target Neighborhood Hits	886	Shared Neighborhood Hits	132
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

MYH11_MOUSE
NC score	0.056303 (rank : 379)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	431	Target Neighborhood Hits	1777	Shared Neighborhood Hits	189
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

IFT74_HUMAN
NC score	0.056295 (rank : 380)	θ value	0.47712 (rank : 198)
Query Neighborhood Hits	431	Target Neighborhood Hits	949	Shared Neighborhood Hits	132
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

ANR26_HUMAN
NC score	0.056274 (rank : 381)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	431	Target Neighborhood Hits	1614	Shared Neighborhood Hits	170
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CXAR_MOUSE
NC score	0.056258 (rank : 382)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	431	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

CN145_HUMAN
NC score	0.056143 (rank : 383)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	431	Target Neighborhood Hits	1196	Shared Neighborhood Hits	151
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

MECP2_HUMAN
NC score	0.056141 (rank : 384)	θ value	0.00134147 (rank : 99)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	14
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

NEUL1_HUMAN
NC score	0.056017 (rank : 385)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	431	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

GOGA6_HUMAN
NC score	0.055560 (rank : 386)	θ value	8.99809 (rank : 413)
Query Neighborhood Hits	431	Target Neighborhood Hits	1007	Shared Neighborhood Hits	147
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CROCC_MOUSE
NC score	0.055536 (rank : 387)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	431	Target Neighborhood Hits	1460	Shared Neighborhood Hits	160
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

LRC45_HUMAN
NC score	0.055497 (rank : 388)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	431	Target Neighborhood Hits	933	Shared Neighborhood Hits	143
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CROCC_HUMAN
NC score	0.055489 (rank : 389)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	431	Target Neighborhood Hits	1409	Shared Neighborhood Hits	166
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RFFL_MOUSE
NC score	0.055487 (rank : 390)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	431	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

CEP63_HUMAN
NC score	0.055107 (rank : 391)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	431	Target Neighborhood Hits	1005	Shared Neighborhood Hits	141
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

HMMR_MOUSE
NC score	0.055101 (rank : 392)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	431	Target Neighborhood Hits	1178	Shared Neighborhood Hits	155
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RUFY2_HUMAN
NC score	0.055085 (rank : 393)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	431	Target Neighborhood Hits	1208	Shared Neighborhood Hits	147
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

REST_MOUSE
NC score	0.055016 (rank : 394)	θ value	4.03905 (rank : 350)
Query Neighborhood Hits	431	Target Neighborhood Hits	1506	Shared Neighborhood Hits	167
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

EEA1_MOUSE
NC score	0.054982 (rank : 395)	θ value	3.0926 (rank : 322)
Query Neighborhood Hits	431	Target Neighborhood Hits	1637	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

RINI_HUMAN
NC score	0.054709 (rank : 396)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	431	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.054675 (rank : 397)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	431	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

CCD19_HUMAN
NC score	0.054631 (rank : 398)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	431	Target Neighborhood Hits	639	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CD80_HUMAN
NC score	0.054582 (rank : 399)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	431	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

EP15R_HUMAN
NC score	0.054528 (rank : 400)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	431	Target Neighborhood Hits	1083	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

CNTRB_HUMAN
NC score	0.054326 (rank : 401)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	431	Target Neighborhood Hits	690	Shared Neighborhood Hits	120
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

RB6I2_HUMAN
NC score	0.054243 (rank : 402)	θ value	0.21417 (rank : 164)
Query Neighborhood Hits	431	Target Neighborhood Hits	1584	Shared Neighborhood Hits	169
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CI093_HUMAN
NC score	0.054216 (rank : 403)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	431	Target Neighborhood Hits	1088	Shared Neighborhood Hits	148
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CE152_HUMAN
NC score	0.053927 (rank : 404)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	431	Target Neighborhood Hits	976	Shared Neighborhood Hits	141
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

NEURL_MOUSE
NC score	0.053750 (rank : 405)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	431	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

DYNA_MOUSE
NC score	0.053676 (rank : 406)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	431	Target Neighborhood Hits	1084	Shared Neighborhood Hits	152
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

KTN1_MOUSE
NC score	0.053564 (rank : 407)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	431	Target Neighborhood Hits	1324	Shared Neighborhood Hits	160
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

RRBP1_MOUSE
NC score	0.053292 (rank : 408)	θ value	4.03905 (rank : 351)
Query Neighborhood Hits	431	Target Neighborhood Hits	1650	Shared Neighborhood Hits	194
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RAD50_MOUSE
NC score	0.053227 (rank : 409)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	431	Target Neighborhood Hits	1366	Shared Neighborhood Hits	158
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TARA_HUMAN
NC score	0.053134 (rank : 410)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	431	Target Neighborhood Hits	1626	Shared Neighborhood Hits	179
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHLB2_MOUSE
NC score	0.053132 (rank : 411)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	431	Target Neighborhood Hits	1016	Shared Neighborhood Hits	143
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RB6I2_MOUSE
NC score	0.053035 (rank : 412)	θ value	0.47712 (rank : 202)
Query Neighborhood Hits	431	Target Neighborhood Hits	1433	Shared Neighborhood Hits	162
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

IFT74_MOUSE
NC score	0.052992 (rank : 413)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	431	Target Neighborhood Hits	939	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CCD27_HUMAN
NC score	0.052919 (rank : 414)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	431	Target Neighborhood Hits	594	Shared Neighborhood Hits	111
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

SWP70_MOUSE
NC score	0.052845 (rank : 415)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	431	Target Neighborhood Hits	1097	Shared Neighborhood Hits	147
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CP135_MOUSE
NC score	0.052745 (rank : 416)	θ value	3.0926 (rank : 319)
Query Neighborhood Hits	431	Target Neighborhood Hits	1278	Shared Neighborhood Hits	156
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CI039_HUMAN
NC score	0.052726 (rank : 417)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	431	Target Neighborhood Hits	1171	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

BPAEA_MOUSE
NC score	0.052631 (rank : 418)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	431	Target Neighborhood Hits	1480	Shared Neighborhood Hits	167
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SYCP1_HUMAN
NC score	0.052611 (rank : 419)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	431	Target Neighborhood Hits	1313	Shared Neighborhood Hits	155
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SM1L2_MOUSE
NC score	0.052601 (rank : 420)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	431	Target Neighborhood Hits	918	Shared Neighborhood Hits	135
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

KTN1_HUMAN
NC score	0.052591 (rank : 421)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	431	Target Neighborhood Hits	1197	Shared Neighborhood Hits	148
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CYLN2_MOUSE
NC score	0.052458 (rank : 422)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	431	Target Neighborhood Hits	1002	Shared Neighborhood Hits	142
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CCD91_HUMAN
NC score	0.052446 (rank : 423)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	431	Target Neighborhood Hits	868	Shared Neighborhood Hits	129
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CUTL1_MOUSE
NC score	0.052384 (rank : 424)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	431	Target Neighborhood Hits	1620	Shared Neighborhood Hits	175
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

MKRN4_HUMAN
NC score	0.052375 (rank : 425)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	431	Target Neighborhood Hits	147	Shared Neighborhood Hits	32
SwissProt Accessions	Q13434	Gene names	MKRN4, RNF64, ZNF127L1
Domain Architecture	No domain graphic available
Description	Makorin-4 (Zinc finger protein 127-Xp) (ZNF127-Xp) (RING finger protein 64).

GRAP1_MOUSE
NC score	0.052360 (rank : 426)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	431	Target Neighborhood Hits	1234	Shared Neighborhood Hits	163
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

GOGA5_MOUSE
NC score	0.052316 (rank : 427)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	431	Target Neighborhood Hits	1434	Shared Neighborhood Hits	166
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

PHLB2_HUMAN
NC score	0.052307 (rank : 428)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	431	Target Neighborhood Hits	964	Shared Neighborhood Hits	141
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

RAD50_HUMAN
NC score	0.052172 (rank : 429)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	431	Target Neighborhood Hits	1317	Shared Neighborhood Hits	147
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

DESP_HUMAN
NC score	0.052043 (rank : 430)	θ value	3.0926 (rank : 321)
Query Neighborhood Hits	431	Target Neighborhood Hits	1470	Shared Neighborhood Hits	169
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

MYH10_MOUSE
NC score	0.051873 (rank : 431)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	431	Target Neighborhood Hits	1612	Shared Neighborhood Hits	180
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MD1L1_MOUSE
NC score	0.051806 (rank : 432)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	431	Target Neighborhood Hits	1001	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

OPTN_MOUSE
NC score	0.051745 (rank : 433)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	431	Target Neighborhood Hits	1120	Shared Neighborhood Hits	141
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CP135_HUMAN
NC score	0.051735 (rank : 434)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	431	Target Neighborhood Hits	1290	Shared Neighborhood Hits	150
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH9_MOUSE
NC score	0.051707 (rank : 435)	θ value	0.813845 (rank : 227)
Query Neighborhood Hits	431	Target Neighborhood Hits	1829	Shared Neighborhood Hits	190
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

K0555_HUMAN
NC score	0.051695 (rank : 436)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	431	Target Neighborhood Hits	880	Shared Neighborhood Hits	131
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

RRBP1_HUMAN
NC score	0.051619 (rank : 437)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	431	Target Neighborhood Hits	1306	Shared Neighborhood Hits	173
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CTGE5_MOUSE
NC score	0.051583 (rank : 438)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	431	Target Neighborhood Hits	928	Shared Neighborhood Hits	130
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

GOGA2_MOUSE
NC score	0.051510 (rank : 439)	θ value	0.813845 (rank : 224)
Query Neighborhood Hits	431	Target Neighborhood Hits	944	Shared Neighborhood Hits	140
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

MYH10_HUMAN
NC score	0.051453 (rank : 440)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	431	Target Neighborhood Hits	1620	Shared Neighborhood Hits	183
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

CEP55_MOUSE
NC score	0.051218 (rank : 441)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	431	Target Neighborhood Hits	693	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

LIPA2_MOUSE
NC score	0.051173 (rank : 442)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	431	Target Neighborhood Hits	1282	Shared Neighborhood Hits	158
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

IF3A_HUMAN
NC score	0.050905 (rank : 443)	θ value	8.99809 (rank : 415)
Query Neighborhood Hits	431	Target Neighborhood Hits	875	Shared Neighborhood Hits	126
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

IFT81_HUMAN
NC score	0.050869 (rank : 444)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	431	Target Neighborhood Hits	893	Shared Neighborhood Hits	138
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

RFIP4_MOUSE
NC score	0.050853 (rank : 445)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	431	Target Neighborhood Hits	708	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BQP8, Q80T87	Gene names	Rab11fip4, Kiaa1821
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 4 (Rab11-FIP4).

IF3A_MOUSE
NC score	0.050834 (rank : 446)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	431	Target Neighborhood Hits	871	Shared Neighborhood Hits	124
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

CING_HUMAN
NC score	0.050800 (rank : 447)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	431	Target Neighborhood Hits	1275	Shared Neighborhood Hits	159
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CK5P2_HUMAN
NC score	0.050627 (rank : 448)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	431	Target Neighborhood Hits	1433	Shared Neighborhood Hits	167
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

PEPL_HUMAN
NC score	0.050561 (rank : 449)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	431	Target Neighborhood Hits	1141	Shared Neighborhood Hits	145
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SMC3_MOUSE
NC score	0.050488 (rank : 450)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	431	Target Neighborhood Hits	1187	Shared Neighborhood Hits	145
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.050459 (rank : 451)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	431	Target Neighborhood Hits	1186	Shared Neighborhood Hits	145
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

GOGA1_MOUSE
NC score	0.050399 (rank : 452)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	431	Target Neighborhood Hits	994	Shared Neighborhood Hits	140
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PIBF1_HUMAN
NC score	0.050399 (rank : 453)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	431	Target Neighborhood Hits	1041	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

HMMR_HUMAN
NC score	0.050067 (rank : 454)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	431	Target Neighborhood Hits	1082	Shared Neighborhood Hits	140
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYH9_HUMAN
NC score	0.050009 (rank : 455)	θ value	1.81305 (rank : 285)
Query Neighborhood Hits	431	Target Neighborhood Hits	1762	Shared Neighborhood Hits	186
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CYTSA_HUMAN
NC score	0.050005 (rank : 456)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	431	Target Neighborhood Hits	1138	Shared Neighborhood Hits	162
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

MYH8_HUMAN
NC score	0.049590 (rank : 457)	θ value	1.81305 (rank : 284)
Query Neighborhood Hits	431	Target Neighborhood Hits	1610	Shared Neighborhood Hits	177
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
NC score	0.049155 (rank : 458)	θ value	1.06291 (rank : 243)
Query Neighborhood Hits	431	Target Neighborhood Hits	1600	Shared Neighborhood Hits	177
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CCD39_HUMAN
NC score	0.048995 (rank : 459)	θ value	2.36792 (rank : 293)
Query Neighborhood Hits	431	Target Neighborhood Hits	868	Shared Neighborhood Hits	128
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

GOGA5_HUMAN
NC score	0.048831 (rank : 460)	θ value	2.36792 (rank : 301)
Query Neighborhood Hits	431	Target Neighborhood Hits	1168	Shared Neighborhood Hits	147
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

CJ118_MOUSE
NC score	0.048659 (rank : 461)	θ value	0.365318 (rank : 183)
Query Neighborhood Hits	431	Target Neighborhood Hits	1132	Shared Neighborhood Hits	141
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

PLEC1_HUMAN
NC score	0.048528 (rank : 462)	θ value	0.62314 (rank : 214)
Query Neighborhood Hits	431	Target Neighborhood Hits	1326	Shared Neighborhood Hits	160
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SMC4_MOUSE
NC score	0.048114 (rank : 463)	θ value	0.0961366 (rank : 141)
Query Neighborhood Hits	431	Target Neighborhood Hits	830	Shared Neighborhood Hits	118
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

MYH14_MOUSE
NC score	0.047592 (rank : 464)	θ value	3.0926 (rank : 329)
Query Neighborhood Hits	431	Target Neighborhood Hits	1225	Shared Neighborhood Hits	158
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PEPL_MOUSE
NC score	0.047566 (rank : 465)	θ value	1.81305 (rank : 288)
Query Neighborhood Hits	431	Target Neighborhood Hits	1105	Shared Neighborhood Hits	143
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

MYH2_HUMAN
NC score	0.046567 (rank : 466)	θ value	0.813845 (rank : 226)
Query Neighborhood Hits	431	Target Neighborhood Hits	1491	Shared Neighborhood Hits	169
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

CEP57_MOUSE
NC score	0.046443 (rank : 467)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	431	Target Neighborhood Hits	580	Shared Neighborhood Hits	108
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

SAS6_MOUSE
NC score	0.046371 (rank : 468)	θ value	1.81305 (rank : 289)
Query Neighborhood Hits	431	Target Neighborhood Hits	931	Shared Neighborhood Hits	125
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

CEP57_HUMAN
NC score	0.045984 (rank : 469)	θ value	0.62314 (rank : 210)
Query Neighborhood Hits	431	Target Neighborhood Hits	576	Shared Neighborhood Hits	109
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

LETM1_MOUSE
NC score	0.045741 (rank : 470)	θ value	1.06291 (rank : 242)
Query Neighborhood Hits	431	Target Neighborhood Hits	240	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

SWP70_HUMAN
NC score	0.045737 (rank : 471)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	431	Target Neighborhood Hits	973	Shared Neighborhood Hits	134
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

NDE1_MOUSE
NC score	0.045519 (rank : 472)	θ value	1.06291 (rank : 245)
Query Neighborhood Hits	431	Target Neighborhood Hits	602	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CZA6, Q3UBS6, Q3UIC1, Q9ERR0	Gene names	Nde1, Nude
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE) (mNudE).

MYO5C_HUMAN
NC score	0.045303 (rank : 473)	θ value	0.813845 (rank : 228)
Query Neighborhood Hits	431	Target Neighborhood Hits	1206	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

LETM1_HUMAN
NC score	0.045128 (rank : 474)	θ value	0.163984 (rank : 155)
Query Neighborhood Hits	431	Target Neighborhood Hits	338	Shared Neighborhood Hits	72
SwissProt Accessions	O95202, Q9UF65	Gene names	LETM1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

CJ118_HUMAN
NC score	0.045016 (rank : 475)	θ value	8.99809 (rank : 410)
Query Neighborhood Hits	431	Target Neighborhood Hits	937	Shared Neighborhood Hits	126
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

SMC4_HUMAN
NC score	0.044841 (rank : 476)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	431	Target Neighborhood Hits	937	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SKI_MOUSE
NC score	0.044667 (rank : 477)	θ value	0.813845 (rank : 231)
Query Neighborhood Hits	431	Target Neighborhood Hits	423	Shared Neighborhood Hits	101
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

LIPA3_HUMAN
NC score	0.044508 (rank : 478)	θ value	0.47712 (rank : 199)
Query Neighborhood Hits	431	Target Neighborhood Hits	828	Shared Neighborhood Hits	124
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

HOOK1_HUMAN
NC score	0.043641 (rank : 479)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	431	Target Neighborhood Hits	942	Shared Neighborhood Hits	125
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MYH13_HUMAN
NC score	0.043415 (rank : 480)	θ value	1.81305 (rank : 283)
Query Neighborhood Hits	431	Target Neighborhood Hits	1504	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

DMD_MOUSE
NC score	0.041007 (rank : 481)	θ value	8.99809 (rank : 412)
Query Neighborhood Hits	431	Target Neighborhood Hits	1111	Shared Neighborhood Hits	140
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

MYH14_HUMAN
NC score	0.040933 (rank : 482)	θ value	4.03905 (rank : 344)
Query Neighborhood Hits	431	Target Neighborhood Hits	995	Shared Neighborhood Hits	132
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

STIM1_MOUSE
NC score	0.040282 (rank : 483)	θ value	4.03905 (rank : 353)
Query Neighborhood Hits	431	Target Neighborhood Hits	660	Shared Neighborhood Hits	119
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

LIPA3_MOUSE
NC score	0.039744 (rank : 484)	θ value	1.81305 (rank : 281)
Query Neighborhood Hits	431	Target Neighborhood Hits	636	Shared Neighborhood Hits	112
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB1_MOUSE
NC score	0.039623 (rank : 485)	θ value	0.813845 (rank : 225)
Query Neighborhood Hits	431	Target Neighborhood Hits	727	Shared Neighborhood Hits	122
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

PHLB3_HUMAN
NC score	0.039497 (rank : 486)	θ value	1.06291 (rank : 246)
Query Neighborhood Hits	431	Target Neighborhood Hits	304	Shared Neighborhood Hits	63
SwissProt Accessions	Q6NSJ2, Q8N7Z4	Gene names	PHLDB3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 3.

MACF4_HUMAN
NC score	0.039466 (rank : 487)	θ value	0.365318 (rank : 186)
Query Neighborhood Hits	431	Target Neighborhood Hits	1321	Shared Neighborhood Hits	144
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CCD96_HUMAN
NC score	0.038335 (rank : 488)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	431	Target Neighborhood Hits	595	Shared Neighborhood Hits	103
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

PRC1_MOUSE
NC score	0.037845 (rank : 489)	θ value	4.03905 (rank : 348)
Query Neighborhood Hits	431	Target Neighborhood Hits	382	Shared Neighborhood Hits	92
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

SRRM2_HUMAN
NC score	0.037820 (rank : 490)	θ value	0.00665767 (rank : 112)
Query Neighborhood Hits	431	Target Neighborhood Hits	1296	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IF2P_HUMAN
NC score	0.037669 (rank : 491)	θ value	8.99809 (rank : 414)
Query Neighborhood Hits	431	Target Neighborhood Hits	889	Shared Neighborhood Hits	106
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

INVO_MOUSE
NC score	0.037250 (rank : 492)	θ value	2.36792 (rank : 305)
Query Neighborhood Hits	431	Target Neighborhood Hits	474	Shared Neighborhood Hits	76
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

TNNT2_HUMAN
NC score	0.037238 (rank : 493)	θ value	0.279714 (rank : 178)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	78
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

JIP3_MOUSE
NC score	0.037158 (rank : 494)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	431	Target Neighborhood Hits	759	Shared Neighborhood Hits	133
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

SKI_HUMAN
NC score	0.037106 (rank : 495)	θ value	1.06291 (rank : 250)
Query Neighborhood Hits	431	Target Neighborhood Hits	423	Shared Neighborhood Hits	96
SwissProt Accessions	P12755, Q5SYT7	Gene names	SKI
Domain Architecture
Description	Ski oncogene (C-ski).

BSN_HUMAN
NC score	0.037075 (rank : 496)	θ value	3.0926 (rank : 317)
Query Neighborhood Hits	431	Target Neighborhood Hits	1537	Shared Neighborhood Hits	158
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
NC score	0.035904 (rank : 497)	θ value	2.36792 (rank : 292)
Query Neighborhood Hits	431	Target Neighborhood Hits	2057	Shared Neighborhood Hits	172
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ACINU_HUMAN
NC score	0.035866 (rank : 498)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	431	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DZIP1_HUMAN
NC score	0.035577 (rank : 499)	θ value	0.813845 (rank : 221)
Query Neighborhood Hits	431	Target Neighborhood Hits	675	Shared Neighborhood Hits	88
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

APOA4_MOUSE
NC score	0.034770 (rank : 500)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	431	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

ACINU_MOUSE
NC score	0.034606 (rank : 501)	θ value	0.62314 (rank : 207)
Query Neighborhood Hits	431	Target Neighborhood Hits	712	Shared Neighborhood Hits	99
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ITSN2_MOUSE
NC score	0.034500 (rank : 502)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	431	Target Neighborhood Hits	1371	Shared Neighborhood Hits	146
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RP1L1_HUMAN
NC score	0.034391 (rank : 503)	θ value	0.0736092 (rank : 134)
Query Neighborhood Hits	431	Target Neighborhood Hits	1072	Shared Neighborhood Hits	120
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ITSN1_MOUSE
NC score	0.034208 (rank : 504)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	431	Target Neighborhood Hits	1669	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CTAG2_HUMAN
NC score	0.034043 (rank : 505)	θ value	0.21417 (rank : 161)
Query Neighborhood Hits	431	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	O75638, O75637, Q9BU80, Q9UJ89, Q9Y479	Gene names	CTAG2, ESO2, LAGE1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen 2 (L antigen family member 1) (LAGE-1 protein) (ESO-2 protein).

TNNT2_MOUSE
NC score	0.034008 (rank : 506)	θ value	0.21417 (rank : 166)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	73
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

CN045_HUMAN
NC score	0.033963 (rank : 507)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	431	Target Neighborhood Hits	227	Shared Neighborhood Hits	60
SwissProt Accessions	Q8ND07, Q9H5P8	Gene names	C14orf45
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf45.

TAF4_HUMAN
NC score	0.033568 (rank : 508)	θ value	0.0961366 (rank : 142)
Query Neighborhood Hits	431	Target Neighborhood Hits	687	Shared Neighborhood Hits	87
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SDPR_HUMAN
NC score	0.033033 (rank : 509)	θ value	5.27518 (rank : 377)
Query Neighborhood Hits	431	Target Neighborhood Hits	337	Shared Neighborhood Hits	68
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SRRM2_MOUSE
NC score	0.032629 (rank : 510)	θ value	0.21417 (rank : 165)
Query Neighborhood Hits	431	Target Neighborhood Hits	1470	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MYO6_HUMAN
NC score	0.031774 (rank : 511)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	431	Target Neighborhood Hits	727	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MOES_MOUSE
NC score	0.031339 (rank : 512)	θ value	2.36792 (rank : 308)
Query Neighborhood Hits	431	Target Neighborhood Hits	923	Shared Neighborhood Hits	127
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CHCH3_HUMAN
NC score	0.031328 (rank : 513)	θ value	1.06291 (rank : 238)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NX63	Gene names	CHCHD3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

SRRM1_MOUSE
NC score	0.031228 (rank : 514)	θ value	0.0193708 (rank : 120)
Query Neighborhood Hits	431	Target Neighborhood Hits	966	Shared Neighborhood Hits	81
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ANR18_HUMAN
NC score	0.030716 (rank : 515)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	431	Target Neighborhood Hits	1106	Shared Neighborhood Hits	134
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

NCOR2_HUMAN
NC score	0.030180 (rank : 516)	θ value	0.0148317 (rank : 117)
Query Neighborhood Hits	431	Target Neighborhood Hits	870	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MOES_HUMAN
NC score	0.029851 (rank : 517)	θ value	4.03905 (rank : 343)
Query Neighborhood Hits	431	Target Neighborhood Hits	892	Shared Neighborhood Hits	129
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

CHCH3_MOUSE
NC score	0.029483 (rank : 518)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	431	Target Neighborhood Hits	249	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CRB9	Gene names	Chchd3
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.

MYO6_MOUSE
NC score	0.028964 (rank : 519)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	431	Target Neighborhood Hits	586	Shared Neighborhood Hits	98
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO10_HUMAN
NC score	0.028887 (rank : 520)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	431	Target Neighborhood Hits	920	Shared Neighborhood Hits	122
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

GRIN1_HUMAN
NC score	0.028645 (rank : 521)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	431	Target Neighborhood Hits	681	Shared Neighborhood Hits	75
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TM108_HUMAN
NC score	0.027884 (rank : 522)	θ value	0.0736092 (rank : 135)
Query Neighborhood Hits	431	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

MARCS_HUMAN
NC score	0.027534 (rank : 523)	θ value	0.163984 (rank : 156)
Query Neighborhood Hits	431	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

LBXCO_MOUSE
NC score	0.027433 (rank : 524)	θ value	0.0961366 (rank : 139)
Query Neighborhood Hits	431	Target Neighborhood Hits	140	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BX46, Q3UYA4, Q5W8I2, Q8C0T2	Gene names	Lbxcor1, Corl1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1 (Transcriptional corepressor Corl1).

AIM2_HUMAN
NC score	0.026706 (rank : 525)	θ value	0.0563607 (rank : 128)
Query Neighborhood Hits	431	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

SPTA2_HUMAN
NC score	0.026466 (rank : 526)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	431	Target Neighborhood Hits	888	Shared Neighborhood Hits	105
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ITSN2_HUMAN
NC score	0.026039 (rank : 527)	θ value	8.99809 (rank : 417)
Query Neighborhood Hits	431	Target Neighborhood Hits	1173	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MARCS_MOUSE
NC score	0.025842 (rank : 528)	θ value	0.62314 (rank : 212)
Query Neighborhood Hits	431	Target Neighborhood Hits	227	Shared Neighborhood Hits	26
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

NUP93_HUMAN
NC score	0.025773 (rank : 529)	θ value	0.125558 (rank : 145)
Query Neighborhood Hits	431	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1F7, Q14705	Gene names	NUP93, KIAA0095
Domain Architecture
Description	Nuclear pore complex protein Nup93 (Nucleoporin Nup93) (93 kDa nucleoporin).

PPRB_MOUSE
NC score	0.024999 (rank : 530)	θ value	0.0431538 (rank : 125)
Query Neighborhood Hits	431	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

KIF11_HUMAN
NC score	0.024755 (rank : 531)	θ value	0.163984 (rank : 154)
Query Neighborhood Hits	431	Target Neighborhood Hits	583	Shared Neighborhood Hits	98
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

MRCKB_HUMAN
NC score	0.023941 (rank : 532)	θ value	0.0736092 (rank : 133)
Query Neighborhood Hits	431	Target Neighborhood Hits	2239	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NFH_HUMAN
NC score	0.023906 (rank : 533)	θ value	0.0113563 (rank : 114)
Query Neighborhood Hits	431	Target Neighborhood Hits	1242	Shared Neighborhood Hits	132
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BAT2_HUMAN
NC score	0.023713 (rank : 534)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	431	Target Neighborhood Hits	931	Shared Neighborhood Hits	76
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EGLN1_HUMAN
NC score	0.023272 (rank : 535)	θ value	0.00665767 (rank : 110)
Query Neighborhood Hits	431	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

MRCKB_MOUSE
NC score	0.022840 (rank : 536)	θ value	2.36792 (rank : 309)
Query Neighborhood Hits	431	Target Neighborhood Hits	2180	Shared Neighborhood Hits	178
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

PRP1_HUMAN
NC score	0.022217 (rank : 537)	θ value	0.0961366 (rank : 140)
Query Neighborhood Hits	431	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

CE016_HUMAN
NC score	0.022145 (rank : 538)	θ value	0.279714 (rank : 167)
Query Neighborhood Hits	431	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NC24, Q6P4E7, Q6UXY2	Gene names	C5orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf16.

BAT2_MOUSE
NC score	0.022084 (rank : 539)	θ value	1.81305 (rank : 274)
Query Neighborhood Hits	431	Target Neighborhood Hits	947	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

K1HA_HUMAN
NC score	0.021629 (rank : 540)	θ value	2.36792 (rank : 306)
Query Neighborhood Hits	431	Target Neighborhood Hits	502	Shared Neighborhood Hits	104
SwissProt Accessions	O76009	Gene names	KRTHA3A, HHA3-I, HKA3A
Domain Architecture
Description	Keratin, type I cuticular Ha3-I (Hair keratin, type I Ha3-I).

TCP10_HUMAN
NC score	0.021564 (rank : 541)	θ value	1.06291 (rank : 254)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

SRRM1_HUMAN
NC score	0.021462 (rank : 542)	θ value	0.813845 (rank : 232)
Query Neighborhood Hits	431	Target Neighborhood Hits	690	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

K1HB_HUMAN
NC score	0.021018 (rank : 543)	θ value	1.81305 (rank : 280)
Query Neighborhood Hits	431	Target Neighborhood Hits	470	Shared Neighborhood Hits	96
SwissProt Accessions	Q14525, O76010	Gene names	KRTHA3B, HHA3-II, HKA3B
Domain Architecture
Description	Keratin, type I cuticular Ha3-II (Hair keratin, type I Ha3-II).

LARP1_HUMAN
NC score	0.020827 (rank : 544)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	431	Target Neighborhood Hits	242	Shared Neighborhood Hits	26
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

K1H1_HUMAN
NC score	0.020120 (rank : 545)	θ value	0.0736092 (rank : 132)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	80
SwissProt Accessions	Q15323	Gene names	KRTHA1, HHA1, HKA1
Domain Architecture
Description	Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1).

NACAM_MOUSE
NC score	0.019389 (rank : 546)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	431	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CCAR1_MOUSE
NC score	0.019168 (rank : 547)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	431	Target Neighborhood Hits	414	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

SPTN4_HUMAN
NC score	0.018859 (rank : 548)	θ value	2.36792 (rank : 314)
Query Neighborhood Hits	431	Target Neighborhood Hits	570	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

TBCA_MOUSE
NC score	0.018314 (rank : 549)	θ value	3.0926 (rank : 335)
Query Neighborhood Hits	431	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P48428	Gene names	Tbca
Domain Architecture
Description	Tubulin-specific chaperone A (Tubulin-folding cofactor A) (CFA) (TCP1- chaperonin cofactor A).

BAP31_MOUSE
NC score	0.018205 (rank : 550)	θ value	1.81305 (rank : 273)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	34
SwissProt Accessions	Q61335, Q9D0E9, Q9D8G7	Gene names	Bcap31, Bap31
Domain Architecture
Description	B-cell receptor-associated protein 31 (BCR-associated protein Bap31) (p28 Bap31).

T22D2_HUMAN
NC score	0.017593 (rank : 551)	θ value	0.813845 (rank : 233)
Query Neighborhood Hits	431	Target Neighborhood Hits	250	Shared Neighborhood Hits	21
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ANR11_HUMAN
NC score	0.017003 (rank : 552)	θ value	0.21417 (rank : 159)
Query Neighborhood Hits	431	Target Neighborhood Hits	1289	Shared Neighborhood Hits	124
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

TP53B_MOUSE
NC score	0.016959 (rank : 553)	θ value	4.03905 (rank : 355)
Query Neighborhood Hits	431	Target Neighborhood Hits	644	Shared Neighborhood Hits	56
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

T2FA_HUMAN
NC score	0.016758 (rank : 554)	θ value	1.06291 (rank : 253)
Query Neighborhood Hits	431	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

BASP_HUMAN
NC score	0.016671 (rank : 555)	θ value	0.62314 (rank : 208)
Query Neighborhood Hits	431	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

STK10_HUMAN
NC score	0.016517 (rank : 556)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	431	Target Neighborhood Hits	1921	Shared Neighborhood Hits	162
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MAGE1_HUMAN
NC score	0.016456 (rank : 557)	θ value	0.21417 (rank : 163)
Query Neighborhood Hits	431	Target Neighborhood Hits	1389	Shared Neighborhood Hits	95
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TCOF_MOUSE
NC score	0.016146 (rank : 558)	θ value	0.813845 (rank : 234)
Query Neighborhood Hits	431	Target Neighborhood Hits	471	Shared Neighborhood Hits	33
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TMC2_HUMAN
NC score	0.015818 (rank : 559)	θ value	0.125558 (rank : 149)
Query Neighborhood Hits	431	Target Neighborhood Hits	149	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

FMN2_HUMAN
NC score	0.015488 (rank : 560)	θ value	0.163984 (rank : 152)
Query Neighborhood Hits	431	Target Neighborhood Hits	484	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

CDT1_HUMAN
NC score	0.015468 (rank : 561)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

GA2L1_HUMAN
NC score	0.015123 (rank : 562)	θ value	1.06291 (rank : 239)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	24
SwissProt Accessions	Q99501, Q53EN7, Q92640, Q9BUY9	Gene names	GAS2L1, GAR22
Domain Architecture
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein).

APBB1_HUMAN
NC score	0.015109 (rank : 563)	θ value	0.0961366 (rank : 138)
Query Neighborhood Hits	431	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

GPTC8_HUMAN
NC score	0.015095 (rank : 564)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	431	Target Neighborhood Hits	366	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TX13A_HUMAN
NC score	0.014999 (rank : 565)	θ value	2.36792 (rank : 315)
Query Neighborhood Hits	431	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXU3, Q32NB6	Gene names	TEX13A
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 13A protein.

DNM3A_MOUSE
NC score	0.014823 (rank : 566)	θ value	0.279714 (rank : 170)
Query Neighborhood Hits	431	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O88508, Q3UH24, Q8CJ60, Q922J0, Q9CSE1	Gene names	Dnmt3a
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA).

SLK_MOUSE
NC score	0.014774 (rank : 567)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	431	Target Neighborhood Hits	1798	Shared Neighborhood Hits	153
SwissProt Accessions	O54988, Q80U65, Q8CAU2, Q8CDW2, Q9WU41	Gene names	Slk, Kiaa0204, Stk2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (mSLK) (Serine/threonine-protein kinase 2) (STE20-related kinase SMAK) (Etk4).

TENS1_HUMAN
NC score	0.014587 (rank : 568)	θ value	0.813845 (rank : 235)
Query Neighborhood Hits	431	Target Neighborhood Hits	400	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

MBD2_MOUSE
NC score	0.014351 (rank : 569)	θ value	2.36792 (rank : 307)
Query Neighborhood Hits	431	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

SEP10_MOUSE
NC score	0.014344 (rank : 570)	θ value	0.813845 (rank : 230)
Query Neighborhood Hits	431	Target Neighborhood Hits	145	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

CABIN_HUMAN
NC score	0.014254 (rank : 571)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	431	Target Neighborhood Hits	490	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

PRP2_MOUSE
NC score	0.014238 (rank : 572)	θ value	1.38821 (rank : 269)
Query Neighborhood Hits	431	Target Neighborhood Hits	347	Shared Neighborhood Hits	30
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

SLK_HUMAN
NC score	0.014085 (rank : 573)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	431	Target Neighborhood Hits	1775	Shared Neighborhood Hits	151
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

IL3B2_MOUSE
NC score	0.013626 (rank : 574)	θ value	2.36792 (rank : 303)
Query Neighborhood Hits	431	Target Neighborhood Hits	372	Shared Neighborhood Hits	32
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

CO1A1_MOUSE
NC score	0.013607 (rank : 575)	θ value	0.279714 (rank : 168)
Query Neighborhood Hits	431	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

FILA_HUMAN
NC score	0.013537 (rank : 576)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	431	Target Neighborhood Hits	685	Shared Neighborhood Hits	56
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

IL3RB_MOUSE
NC score	0.013286 (rank : 577)	θ value	2.36792 (rank : 304)
Query Neighborhood Hits	431	Target Neighborhood Hits	355	Shared Neighborhood Hits	29
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

PI5PA_HUMAN
NC score	0.013225 (rank : 578)	θ value	3.0926 (rank : 332)
Query Neighborhood Hits	431	Target Neighborhood Hits	749	Shared Neighborhood Hits	63
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SFRS2_HUMAN
NC score	0.012972 (rank : 579)	θ value	0.365318 (rank : 189)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q01130	Gene names	SFRS2
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264).

SFRS2_MOUSE
NC score	0.012972 (rank : 580)	θ value	0.365318 (rank : 190)
Query Neighborhood Hits	431	Target Neighborhood Hits	222	Shared Neighborhood Hits	13
SwissProt Accessions	Q62093, Q542L3, Q60701	Gene names	Sfrs2, Pr264, Sfrs10
Domain Architecture
Description	Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1).

CD016_HUMAN
NC score	0.012842 (rank : 581)	θ value	8.99809 (rank : 409)
Query Neighborhood Hits	431	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	Q63HQ0, Q96GG6, Q9H0V0, Q9P1L4	Gene names	C4orf16
Domain Architecture	No domain graphic available
Description	Protein C4orf16.

SCG1_MOUSE
NC score	0.012584 (rank : 582)	θ value	2.36792 (rank : 312)
Query Neighborhood Hits	431	Target Neighborhood Hits	163	Shared Neighborhood Hits	18
SwissProt Accessions	P16014	Gene names	Chgb, Scg-1, Scg1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB).

CO1A1_HUMAN
NC score	0.012414 (rank : 583)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	431	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

M4K4_MOUSE
NC score	0.012323 (rank : 584)	θ value	0.21417 (rank : 162)
Query Neighborhood Hits	431	Target Neighborhood Hits	1560	Shared Neighborhood Hits	132
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

ATX2L_MOUSE
NC score	0.012284 (rank : 585)	θ value	2.36792 (rank : 291)
Query Neighborhood Hits	431	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

FA47B_HUMAN
NC score	0.012188 (rank : 586)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	431	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

ASPH_HUMAN
NC score	0.011956 (rank : 587)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	18
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

IF4B_HUMAN
NC score	0.011931 (rank : 588)	θ value	3.0926 (rank : 323)
Query Neighborhood Hits	431	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

NSD1_MOUSE
NC score	0.011863 (rank : 589)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	431	Target Neighborhood Hits	472	Shared Neighborhood Hits	40
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

CCNL1_HUMAN
NC score	0.011721 (rank : 590)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	431	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

KI13A_MOUSE
NC score	0.011700 (rank : 591)	θ value	4.03905 (rank : 342)
Query Neighborhood Hits	431	Target Neighborhood Hits	395	Shared Neighborhood Hits	85
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

DVL2_HUMAN
NC score	0.011688 (rank : 592)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	431	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

SEPT9_HUMAN
NC score	0.011558 (rank : 593)	θ value	2.36792 (rank : 313)
Query Neighborhood Hits	431	Target Neighborhood Hits	706	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CO5A2_HUMAN
NC score	0.011482 (rank : 594)	θ value	1.81305 (rank : 276)
Query Neighborhood Hits	431	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ATX2_MOUSE
NC score	0.011396 (rank : 595)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	431	Target Neighborhood Hits	445	Shared Neighborhood Hits	38
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

M4K4_HUMAN
NC score	0.011125 (rank : 596)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	431	Target Neighborhood Hits	1589	Shared Neighborhood Hits	132
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SEP10_HUMAN
NC score	0.011122 (rank : 597)	θ value	1.38821 (rank : 270)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

SYN1_HUMAN
NC score	0.011113 (rank : 598)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	431	Target Neighborhood Hits	419	Shared Neighborhood Hits	44
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYN1_MOUSE
NC score	0.011078 (rank : 599)	θ value	5.27518 (rank : 379)
Query Neighborhood Hits	431	Target Neighborhood Hits	363	Shared Neighborhood Hits	37
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SYN2_HUMAN
NC score	0.010905 (rank : 600)	θ value	4.03905 (rank : 354)
Query Neighborhood Hits	431	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

CCNL1_MOUSE
NC score	0.010873 (rank : 601)	θ value	2.36792 (rank : 296)
Query Neighborhood Hits	431	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

DNM3A_HUMAN
NC score	0.010826 (rank : 602)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	431	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

RECQ5_HUMAN
NC score	0.010563 (rank : 603)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	431	Target Neighborhood Hits	390	Shared Neighborhood Hits	40
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SFRS4_HUMAN
NC score	0.010554 (rank : 604)	θ value	0.62314 (rank : 215)
Query Neighborhood Hits	431	Target Neighborhood Hits	384	Shared Neighborhood Hits	28
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

CF049_HUMAN
NC score	0.010536 (rank : 605)	θ value	0.125558 (rank : 143)
Query Neighborhood Hits	431	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q2TBC4, Q5T3D4, Q9NSV1	Gene names	C6orf49
Domain Architecture	No domain graphic available
Description	Protein C6orf49.

DVL3_HUMAN
NC score	0.010446 (rank : 606)	θ value	2.36792 (rank : 299)
Query Neighborhood Hits	431	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q92997, O14642, Q13531, Q8N5E9, Q92607	Gene names	DVL3, KIAA0208
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

HORN_HUMAN
NC score	0.010344 (rank : 607)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	16
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

RECQ4_HUMAN
NC score	0.010121 (rank : 608)	θ value	0.813845 (rank : 229)
Query Neighborhood Hits	431	Target Neighborhood Hits	177	Shared Neighborhood Hits	19
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

EPN1_HUMAN
NC score	0.010085 (rank : 609)	θ value	0.813845 (rank : 222)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

NCBP1_MOUSE
NC score	0.010033 (rank : 610)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UYV9, Q7TNE8	Gene names	Ncbp1
Domain Architecture	No domain graphic available
Description	Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (NCBP 80 kDa subunit) (CBP80).

MINK1_HUMAN
NC score	0.009925 (rank : 611)	θ value	0.47712 (rank : 200)
Query Neighborhood Hits	431	Target Neighborhood Hits	1477	Shared Neighborhood Hits	121
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

DVL3_MOUSE
NC score	0.009563 (rank : 612)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	431	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q61062	Gene names	Dvl3
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3).

DVL2_MOUSE
NC score	0.009542 (rank : 613)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

RERE_HUMAN
NC score	0.009534 (rank : 614)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	431	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

AFF4_MOUSE
NC score	0.009519 (rank : 615)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	431	Target Neighborhood Hits	581	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

COBA1_HUMAN
NC score	0.009386 (rank : 616)	θ value	1.81305 (rank : 277)
Query Neighborhood Hits	431	Target Neighborhood Hits	491	Shared Neighborhood Hits	41
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SPAG1_HUMAN
NC score	0.009041 (rank : 617)	θ value	3.0926 (rank : 334)
Query Neighborhood Hits	431	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

OTU7A_HUMAN
NC score	0.008656 (rank : 618)	θ value	1.81305 (rank : 286)
Query Neighborhood Hits	431	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

DBP_MOUSE
NC score	0.008493 (rank : 619)	θ value	2.36792 (rank : 298)
Query Neighborhood Hits	431	Target Neighborhood Hits	137	Shared Neighborhood Hits	14
SwissProt Accessions	Q60925, Q8VCX3	Gene names	Dbp
Domain Architecture
Description	D site-binding protein (Albumin D box-binding protein) (Albumin D- element-binding protein).

PIN1_HUMAN
NC score	0.008270 (rank : 620)	θ value	3.0926 (rank : 333)
Query Neighborhood Hits	431	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q13526	Gene names	PIN1
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Rotamase Pin1) (PPIase Pin1).

KIFC2_MOUSE
NC score	0.008086 (rank : 621)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	431	Target Neighborhood Hits	206	Shared Neighborhood Hits	36
SwissProt Accessions	O08672, O08613	Gene names	Kifc2
Domain Architecture
Description	Kinesin-like protein KIFC2.

TBX2_HUMAN
NC score	0.008021 (rank : 622)	θ value	0.163984 (rank : 157)
Query Neighborhood Hits	431	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q13207, Q16424, Q7Z647	Gene names	TBX2
Domain Architecture
Description	T-box transcription factor TBX2 (T-box protein 2).

RALY_HUMAN
NC score	0.008012 (rank : 623)	θ value	4.03905 (rank : 349)
Query Neighborhood Hits	431	Target Neighborhood Hits	127	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

MINK1_MOUSE
NC score	0.007988 (rank : 624)	θ value	0.47712 (rank : 201)
Query Neighborhood Hits	431	Target Neighborhood Hits	1451	Shared Neighborhood Hits	120
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ARMX5_MOUSE
NC score	0.007939 (rank : 625)	θ value	2.36792 (rank : 290)
Query Neighborhood Hits	431	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

CAC1B_MOUSE
NC score	0.007620 (rank : 626)	θ value	0.62314 (rank : 209)
Query Neighborhood Hits	431	Target Neighborhood Hits	351	Shared Neighborhood Hits	30
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CLIC6_MOUSE
NC score	0.007397 (rank : 627)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	431	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHB9	Gene names	Clic6
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

CO5A3_HUMAN
NC score	0.007264 (rank : 628)	θ value	8.99809 (rank : 411)
Query Neighborhood Hits	431	Target Neighborhood Hits	433	Shared Neighborhood Hits	34
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

RFX5_HUMAN
NC score	0.007167 (rank : 629)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	431	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

ISK5_HUMAN
NC score	0.007108 (rank : 630)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	431	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

CO7A1_HUMAN
NC score	0.006922 (rank : 631)	θ value	0.21417 (rank : 160)
Query Neighborhood Hits	431	Target Neighborhood Hits	807	Shared Neighborhood Hits	45
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CAC1B_HUMAN
NC score	0.006797 (rank : 632)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	431	Target Neighborhood Hits	257	Shared Neighborhood Hits	22
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PHX2B_HUMAN
NC score	0.006715 (rank : 633)	θ value	0.125558 (rank : 146)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.006715 (rank : 634)	θ value	0.125558 (rank : 147)
Query Neighborhood Hits	431	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

GNAS1_HUMAN
NC score	0.006670 (rank : 635)	θ value	0.163984 (rank : 153)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	24
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SYNJ1_HUMAN
NC score	0.006594 (rank : 636)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	431	Target Neighborhood Hits	498	Shared Neighborhood Hits	37
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

JIP2_MOUSE
NC score	0.005984 (rank : 637)	θ value	4.03905 (rank : 341)
Query Neighborhood Hits	431	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

PANK1_MOUSE
NC score	0.005970 (rank : 638)	θ value	3.0926 (rank : 331)
Query Neighborhood Hits	431	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4K6, Q9D3K1, Q9QXM8	Gene names	Pank1, Pank
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (mPank1) (mPank).

CSKI1_MOUSE
NC score	0.005925 (rank : 639)	θ value	0.47712 (rank : 195)
Query Neighborhood Hits	431	Target Neighborhood Hits	1031	Shared Neighborhood Hits	62
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ARHGF_HUMAN
NC score	0.005671 (rank : 640)	θ value	8.99809 (rank : 408)
Query Neighborhood Hits	431	Target Neighborhood Hits	214	Shared Neighborhood Hits	22
SwissProt Accessions	O94989, Q8N449, Q9H8B4	Gene names	ARHGEF15, KIAA0915
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 15 (Vsm-RhoGEF).

SHAN1_HUMAN
NC score	0.005549 (rank : 641)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	431	Target Neighborhood Hits	1041	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TF3C1_MOUSE
NC score	0.005539 (rank : 642)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	431	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K284, Q8CAL9	Gene names	Gtf3c1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

SIRT1_HUMAN
NC score	0.005461 (rank : 643)	θ value	4.03905 (rank : 352)
Query Neighborhood Hits	431	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

ITF2_HUMAN
NC score	0.005385 (rank : 644)	θ value	3.0926 (rank : 324)
Query Neighborhood Hits	431	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

MUC5B_HUMAN
NC score	0.005275 (rank : 645)	θ value	2.36792 (rank : 310)
Query Neighborhood Hits	431	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

INT1_HUMAN
NC score	0.005130 (rank : 646)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	431	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N201, Q6NT70, Q6UX74, Q8WV40, Q96D36, Q9NTD1, Q9P2A8, Q9Y3W8	Gene names	INTS1, KIAA1440
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

OSBL5_HUMAN
NC score	0.004868 (rank : 647)	θ value	3.0926 (rank : 330)
Query Neighborhood Hits	431	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

HXA4_MOUSE
NC score	0.004846 (rank : 648)	θ value	0.00665767 (rank : 111)
Query Neighborhood Hits	431	Target Neighborhood Hits	379	Shared Neighborhood Hits	11
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

RGL2_HUMAN
NC score	0.004621 (rank : 649)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	431	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O15211, Q9Y3F3	Gene names	RGL2, RAB2L
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

RGL2_MOUSE
NC score	0.004487 (rank : 650)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	431	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

HNRPG_MOUSE
NC score	0.004181 (rank : 651)	θ value	4.03905 (rank : 340)
Query Neighborhood Hits	431	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	O35479	Gene names	Rbmx, Hnrnpg, Hnrpg, Rbmxp1, Rbmxrt
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein G (hnRNP G) (RNA-binding motif protein, X chromosome).

CSTF2_MOUSE
NC score	0.004071 (rank : 652)	θ value	2.36792 (rank : 297)
Query Neighborhood Hits	431	Target Neighborhood Hits	255	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BIQ5, Q8K1Y6, Q9ERC2	Gene names	Cstf2
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit (CSTF 64 kDa subunit) (CF-1 64 kDa subunit) (CstF-64).

AP3B1_HUMAN
NC score	0.003859 (rank : 653)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	431	Target Neighborhood Hits	283	Shared Neighborhood Hits	11
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

UBP37_HUMAN
NC score	0.003683 (rank : 654)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	431	Target Neighborhood Hits	208	Shared Neighborhood Hits	23
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

DDX10_MOUSE
NC score	0.003646 (rank : 655)	θ value	0.813845 (rank : 220)
Query Neighborhood Hits	431	Target Neighborhood Hits	233	Shared Neighborhood Hits	26
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

HCN4_HUMAN
NC score	0.003589 (rank : 656)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	431	Target Neighborhood Hits	303	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

LR37A_HUMAN
NC score	0.003405 (rank : 657)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	431	Target Neighborhood Hits	720	Shared Neighborhood Hits	46
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

WDR33_HUMAN
NC score	0.003269 (rank : 658)	θ value	0.813845 (rank : 236)
Query Neighborhood Hits	431	Target Neighborhood Hits	638	Shared Neighborhood Hits	30
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

SYT3_MOUSE
NC score	0.002884 (rank : 659)	θ value	0.47712 (rank : 204)
Query Neighborhood Hits	431	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

IP3KA_HUMAN
NC score	0.002865 (rank : 660)	θ value	8.99809 (rank : 416)
Query Neighborhood Hits	431	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

PABP1_HUMAN
NC score	0.002533 (rank : 661)	θ value	4.03905 (rank : 346)
Query Neighborhood Hits	431	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	P11940, Q15097, Q93004	Gene names	PABPC1, PAB1, PABP1, PABPC2
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

PABP1_MOUSE
NC score	0.002514 (rank : 662)	θ value	4.03905 (rank : 347)
Query Neighborhood Hits	431	Target Neighborhood Hits	278	Shared Neighborhood Hits	17
SwissProt Accessions	P29341	Gene names	Pabpc1, Pabp1
Domain Architecture
Description	Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP 1).

ANR47_HUMAN
NC score	0.002386 (rank : 663)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	431	Target Neighborhood Hits	369	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

STAG1_HUMAN
NC score	0.002173 (rank : 664)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	431	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVM7, O00539	Gene names	STAG1, SA1
Domain Architecture
Description	Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1).

KCNH2_HUMAN
NC score	0.001896 (rank : 665)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	431	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

DUS8_HUMAN
NC score	0.001860 (rank : 666)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	431	Target Neighborhood Hits	161	Shared Neighborhood Hits	10
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

ATS12_HUMAN
NC score	0.001474 (rank : 667)	θ value	0.813845 (rank : 219)
Query Neighborhood Hits	431	Target Neighborhood Hits	251	Shared Neighborhood Hits	11
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

RHG06_MOUSE
NC score	0.001430 (rank : 668)	θ value	5.27518 (rank : 376)
Query Neighborhood Hits	431	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

FGD4_HUMAN
NC score	0.001269 (rank : 669)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	431	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

LAP4_MOUSE
NC score	0.000970 (rank : 670)	θ value	0.279714 (rank : 171)
Query Neighborhood Hits	431	Target Neighborhood Hits	590	Shared Neighborhood Hits	26
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

DDX21_MOUSE
NC score	0.000716 (rank : 671)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	431	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

UBP51_HUMAN
NC score	0.000650 (rank : 672)	θ value	5.27518 (rank : 380)
Query Neighborhood Hits	431	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

PP16B_MOUSE
NC score	0.000577 (rank : 673)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	431	Target Neighborhood Hits	302	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

SOX4_HUMAN
NC score	0.000444 (rank : 674)	θ value	5.27518 (rank : 378)
Query Neighborhood Hits	431	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

HXA11_HUMAN
NC score	0.000337 (rank : 675)	θ value	1.81305 (rank : 279)
Query Neighborhood Hits	431	Target Neighborhood Hits	334	Shared Neighborhood Hits	7
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

PP16B_HUMAN
NC score	0.000149 (rank : 676)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	431	Target Neighborhood Hits	307	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

LRCH4_HUMAN
NC score	0.000071 (rank : 677)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	431	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O75427, Q8WV85, Q96ID0	Gene names	LRCH4, LRN, LRRN4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4 (Leucine-rich neuronal protein).

NGN1_MOUSE
NC score	-0.000026 (rank : 678)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	431	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

ADA19_MOUSE
NC score	-0.000949 (rank : 679)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	431	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ZN687_HUMAN
NC score	-0.001893 (rank : 680)	θ value	0.365318 (rank : 194)
Query Neighborhood Hits	431	Target Neighborhood Hits	1244	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

FOG1_MOUSE
NC score	-0.001976 (rank : 681)	θ value	0.813845 (rank : 223)
Query Neighborhood Hits	431	Target Neighborhood Hits	1237	Shared Neighborhood Hits	62
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

NOTC3_HUMAN
NC score	-0.002458 (rank : 682)	θ value	0.365318 (rank : 187)
Query Neighborhood Hits	431	Target Neighborhood Hits	1062	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TLE2_MOUSE
NC score	-0.002595 (rank : 683)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	431	Target Neighborhood Hits	294	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVB2	Gene names	Tle2, Grg2
Domain Architecture
Description	Transducin-like enhancer protein 2.

FBN3_HUMAN
NC score	-0.003734 (rank : 684)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	431	Target Neighborhood Hits	543	Shared Neighborhood Hits	6
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KSR1_HUMAN
NC score	-0.005297 (rank : 685)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	431	Target Neighborhood Hits	867	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

ABL1_MOUSE
NC score	-0.005382 (rank : 686)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	431	Target Neighborhood Hits	1178	Shared Neighborhood Hits	43
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

CD2L5_MOUSE
NC score	-0.006063 (rank : 687)	θ value	3.0926 (rank : 318)
Query Neighborhood Hits	431	Target Neighborhood Hits	1011	Shared Neighborhood Hits	32
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

LTK_HUMAN
NC score	-0.006286 (rank : 688)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	431	Target Neighborhood Hits	774	Shared Neighborhood Hits	17
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MYLK2_HUMAN
NC score	-0.006369 (rank : 689)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	431	Target Neighborhood Hits	920	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

MARK4_MOUSE
NC score	-0.006847 (rank : 690)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	431	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

ADA2A_MOUSE
NC score	-0.008269 (rank : 691)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	431	Target Neighborhood Hits	900	Shared Neighborhood Hits	10
SwissProt Accessions	Q01338	Gene names	Adra2a
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR).

HIC2_HUMAN
NC score	-0.009649 (rank : 692)	θ value	2.36792 (rank : 302)
Query Neighborhood Hits	431	Target Neighborhood Hits	820	Shared Neighborhood Hits	9
SwissProt Accessions	Q96JB3, Q96KR3, Q9NSM9, Q9UPX9	Gene names	HIC2, HRG22, KIAA1020, ZBTB30
Domain Architecture
Description	Hypermethylated in cancer 2 protein (Hic-2) (Hic-3) (HIC1-related gene on chromosome 22) (Zinc finger and BTB domain-containing protein 30).

ZN524_MOUSE
NC score	-0.009899 (rank : 693)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	431	Target Neighborhood Hits	712	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D0B1, Q9DCQ0	Gene names	Znf524, Zfp524
Domain Architecture	No domain graphic available
Description	Zinc finger protein 524.