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Network neighborhood for query Sequence : EGLN1_HUMAN

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EGLN1_HUMAN
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EGLN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

EGLN1_MOUSE
θ value	2.17943e-171 (rank : 2)	NC score	0.981179 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

EGLN2_HUMAN
θ value	1.88829e-90 (rank : 3)	NC score	0.938085 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

EGLN2_MOUSE
θ value	2.46618e-90 (rank : 4)	NC score	0.937681 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

EGLN3_HUMAN
θ value	9.07703e-85 (rank : 5)	NC score	0.944320 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6Z9	Gene names	EGLN3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (HPH-1) (Prolyl hydroxylase domain-containing protein 3) (PHD3).

EGLN3_MOUSE
θ value	5.88354e-84 (rank : 6)	NC score	0.944064 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q91UZ4, Q3TCG8, Q8C8M6, Q8CCA8, Q8R5C7	Gene names	Egln3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (SM-20).

SMYD2_MOUSE
θ value	1.09739e-05 (rank : 7)	NC score	0.242533 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD2_HUMAN
θ value	2.44474e-05 (rank : 8)	NC score	0.240839 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

PDCD2_MOUSE
θ value	0.00020696 (rank : 9)	NC score	0.207466 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

ZMY10_HUMAN
θ value	0.000461057 (rank : 10)	NC score	0.223573 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ZMY10_MOUSE
θ value	0.00102713 (rank : 11)	NC score	0.221223 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

PDCD2_HUMAN
θ value	0.00175202 (rank : 12)	NC score	0.201009 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

DEAF1_MOUSE
θ value	0.00228821 (rank : 13)	NC score	0.192119 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

DEAF1_HUMAN
θ value	0.00298849 (rank : 14)	NC score	0.194029 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

MTG8R_MOUSE
θ value	0.00509761 (rank : 15)	NC score	0.167141 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

ZMY17_MOUSE
θ value	0.00509761 (rank : 16)	NC score	0.230088 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D5Z5	Gene names	Zmynd17
Domain Architecture
Description	Zinc finger MYND domain-containing protein 17.

MEFV_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.023272 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NFH_MOUSE
θ value	0.00665767 (rank : 18)	NC score	0.021039 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	2247	Shared Neighborhood Hits	19
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ANKY2_HUMAN
θ value	0.00869519 (rank : 19)	NC score	0.100706 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	306	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

SMYD3_HUMAN
θ value	0.0113563 (rank : 20)	NC score	0.192494 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

ANKY2_MOUSE
θ value	0.0148317 (rank : 21)	NC score	0.102554 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	316	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

MTG8R_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.161105 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

SMYD3_MOUSE
θ value	0.0330416 (rank : 23)	NC score	0.185534 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

MTG8_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.161699 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	25
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

MUC1_HUMAN
θ value	0.0736092 (rank : 25)	NC score	0.024494 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	975	Shared Neighborhood Hits	13
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZMY19_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.179529 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q96E35	Gene names	ZMYND19, MIZIP
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ZMY19_MOUSE
θ value	0.125558 (rank : 27)	NC score	0.179529 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQG3, Q8K1T3	Gene names	Zmynd19, Mizip
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

SMYD1_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.168151 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD1_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.168332 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

ZAR1_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.049276 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

AIRE_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.041676 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

P3H2_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.084165 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

MARCS_MOUSE
θ value	0.47712 (rank : 33)	NC score	0.065870 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MTG8_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.152426 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

ZMY12_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.116381 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0C1, Q5VUS6, Q8TC87, Q96M51	Gene names	ZMYND12
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 12.

DIDO1_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.026644 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	960	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

HIPK4_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.003064 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	799	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

P3H1_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.079066 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H1_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.082320 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H2_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.069272 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

OGFR_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.042786 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RGS3_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.020886 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	1375	Shared Neighborhood Hits	13
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TRI45_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.029865 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.030263 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

COA2_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.016911 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

PCLO_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.023387 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	2275	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SNPC4_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.025736 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SSBP4_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.020319 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CERU_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.017643 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

FGD3_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.009297 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

MEGF9_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.007709 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CD017_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.025587 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

GRIN1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.026839 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ARFG3_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.008451 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

MAST4_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.001744 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	1804	Shared Neighborhood Hits	16
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TACC3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.008537 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZN553_HUMAN
θ value	6.88961 (rank : 57)	NC score	-0.002147 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

ANK2_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.006700 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	1615	Shared Neighborhood Hits	14
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASTN_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.008499 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

CAC1A_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.004191 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CT043_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.011696 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

SMYD4_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.050760 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.051757 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD5_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.050463 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

Hits sorted by NC score

EGLN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

EGLN1_MOUSE
NC score	0.981179 (rank : 2)	θ value	2.17943e-171 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	43
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

EGLN3_HUMAN
NC score	0.944320 (rank : 3)	θ value	9.07703e-85 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6Z9	Gene names	EGLN3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (HPH-1) (Prolyl hydroxylase domain-containing protein 3) (PHD3).

EGLN3_MOUSE
NC score	0.944064 (rank : 4)	θ value	5.88354e-84 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q91UZ4, Q3TCG8, Q8C8M6, Q8CCA8, Q8R5C7	Gene names	Egln3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (SM-20).

EGLN2_HUMAN
NC score	0.938085 (rank : 5)	θ value	1.88829e-90 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

EGLN2_MOUSE
NC score	0.937681 (rank : 6)	θ value	2.46618e-90 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

SMYD2_MOUSE
NC score	0.242533 (rank : 7)	θ value	1.09739e-05 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD2_HUMAN
NC score	0.240839 (rank : 8)	θ value	2.44474e-05 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

ZMY17_MOUSE
NC score	0.230088 (rank : 9)	θ value	0.00509761 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D5Z5	Gene names	Zmynd17
Domain Architecture
Description	Zinc finger MYND domain-containing protein 17.

ZMY10_HUMAN
NC score	0.223573 (rank : 10)	θ value	0.000461057 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ZMY10_MOUSE
NC score	0.221223 (rank : 11)	θ value	0.00102713 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

PDCD2_MOUSE
NC score	0.207466 (rank : 12)	θ value	0.00020696 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

PDCD2_HUMAN
NC score	0.201009 (rank : 13)	θ value	0.00175202 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

DEAF1_HUMAN
NC score	0.194029 (rank : 14)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

SMYD3_HUMAN
NC score	0.192494 (rank : 15)	θ value	0.0113563 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

DEAF1_MOUSE
NC score	0.192119 (rank : 16)	θ value	0.00228821 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

SMYD3_MOUSE
NC score	0.185534 (rank : 17)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

ZMY19_HUMAN
NC score	0.179529 (rank : 18)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q96E35	Gene names	ZMYND19, MIZIP
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ZMY19_MOUSE
NC score	0.179529 (rank : 19)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQG3, Q8K1T3	Gene names	Zmynd19, Mizip
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

SMYD1_MOUSE
NC score	0.168332 (rank : 20)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

SMYD1_HUMAN
NC score	0.168151 (rank : 21)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	41	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

MTG8R_MOUSE
NC score	0.167141 (rank : 22)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

MTG8_HUMAN
NC score	0.161699 (rank : 23)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	25
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

MTG8R_HUMAN
NC score	0.161105 (rank : 24)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	125	Shared Neighborhood Hits	25
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

MTG8_MOUSE
NC score	0.152426 (rank : 25)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

ZMY12_HUMAN
NC score	0.116381 (rank : 26)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H0C1, Q5VUS6, Q8TC87, Q96M51	Gene names	ZMYND12
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 12.

ANKY2_MOUSE
NC score	0.102554 (rank : 27)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	316	Shared Neighborhood Hits	23
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKY2_HUMAN
NC score	0.100706 (rank : 28)	θ value	0.00869519 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	306	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

P3H2_MOUSE
NC score	0.084165 (rank : 29)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

P3H1_MOUSE
NC score	0.082320 (rank : 30)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	37	Shared Neighborhood Hits	10
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H1_HUMAN
NC score	0.079066 (rank : 31)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H2_HUMAN
NC score	0.069272 (rank : 32)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

MARCS_MOUSE
NC score	0.065870 (rank : 33)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	227	Shared Neighborhood Hits	16
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

SMYD4_MOUSE
NC score	0.051757 (rank : 34)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_HUMAN
NC score	0.050760 (rank : 35)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD5_HUMAN
NC score	0.050463 (rank : 36)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

ZAR1_MOUSE
NC score	0.049276 (rank : 37)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

OGFR_HUMAN
NC score	0.042786 (rank : 38)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	1582	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

AIRE_MOUSE
NC score	0.041676 (rank : 39)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

TRI45_MOUSE
NC score	0.030263 (rank : 40)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI45_HUMAN
NC score	0.029865 (rank : 41)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

GRIN1_HUMAN
NC score	0.026839 (rank : 42)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	681	Shared Neighborhood Hits	15
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DIDO1_HUMAN
NC score	0.026644 (rank : 43)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	960	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SNPC4_HUMAN
NC score	0.025736 (rank : 44)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CD017_HUMAN
NC score	0.025587 (rank : 45)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

MUC1_HUMAN
NC score	0.024494 (rank : 46)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	975	Shared Neighborhood Hits	13
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCLO_MOUSE
NC score	0.023387 (rank : 47)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	2275	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MEFV_HUMAN
NC score	0.023272 (rank : 48)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NFH_MOUSE
NC score	0.021039 (rank : 49)	θ value	0.00665767 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	2247	Shared Neighborhood Hits	19
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_HUMAN
NC score	0.020886 (rank : 50)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	1375	Shared Neighborhood Hits	13
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SSBP4_HUMAN
NC score	0.020319 (rank : 51)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CERU_MOUSE
NC score	0.017643 (rank : 52)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

COA2_HUMAN
NC score	0.016911 (rank : 53)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	O00763, Q16852	Gene names	ACACB, ACC2, ACCB
Domain Architecture
Description	Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) [Includes: Biotin carboxylase (EC 6.3.4.14)].

CT043_MOUSE
NC score	0.011696 (rank : 54)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

FGD3_HUMAN
NC score	0.009297 (rank : 55)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

TACC3_HUMAN
NC score	0.008537 (rank : 56)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ASTN_HUMAN
NC score	0.008499 (rank : 57)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ARFG3_MOUSE
NC score	0.008451 (rank : 58)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

MEGF9_MOUSE
NC score	0.007709 (rank : 59)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ANK2_HUMAN
NC score	0.006700 (rank : 60)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	1615	Shared Neighborhood Hits	14
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CAC1A_MOUSE
NC score	0.004191 (rank : 61)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

HIPK4_HUMAN
NC score	0.003064 (rank : 62)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	799	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE63	Gene names	HIPK4
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 4 (EC 2.7.11.1).

MAST4_HUMAN
NC score	0.001744 (rank : 63)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	1804	Shared Neighborhood Hits	16
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ZN553_HUMAN
NC score	-0.002147 (rank : 64)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.