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Network neighborhood for query Sequence : SMYD3_HUMAN

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SMYD3_HUMAN
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMYD3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
θ value	0 (rank : 2)	NC score	0.998226 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD2_HUMAN
θ value	1.19377e-60 (rank : 3)	NC score	0.916488 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

SMYD1_HUMAN
θ value	5.92465e-60 (rank : 4)	NC score	0.901298 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD2_MOUSE
θ value	7.73779e-60 (rank : 5)	NC score	0.914099 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD1_MOUSE
θ value	6.55044e-59 (rank : 6)	NC score	0.900390 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

SMYD5_HUMAN
θ value	1.02475e-11 (rank : 7)	NC score	0.532411 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

SMYD4_MOUSE
θ value	1.33837e-11 (rank : 8)	NC score	0.487650 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_HUMAN
θ value	2.28291e-11 (rank : 9)	NC score	0.479963 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD5_MOUSE
θ value	7.34386e-10 (rank : 10)	NC score	0.515489 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

ZMY19_HUMAN
θ value	9.29e-05 (rank : 11)	NC score	0.382853 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q96E35	Gene names	ZMYND19, MIZIP
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ZMY19_MOUSE
θ value	9.29e-05 (rank : 12)	NC score	0.382853 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CQG3, Q8K1T3	Gene names	Zmynd19, Mizip
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ANKY2_MOUSE
θ value	0.00020696 (rank : 13)	NC score	0.186791 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKY2_HUMAN
θ value	0.00035302 (rank : 14)	NC score	0.176284 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	306	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

DEAF1_MOUSE
θ value	0.00134147 (rank : 15)	NC score	0.244046 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

DEAF1_HUMAN
θ value	0.00175202 (rank : 16)	NC score	0.240085 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	67	Shared Neighborhood Hits	26
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

ZMY17_MOUSE
θ value	0.00665767 (rank : 17)	NC score	0.344497 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5Z5	Gene names	Zmynd17
Domain Architecture
Description	Zinc finger MYND domain-containing protein 17.

EGLN1_HUMAN
θ value	0.0113563 (rank : 18)	NC score	0.192494 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

MTG8R_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.196658 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

MTG8R_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.198487 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

EGLN1_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.196510 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

MTG8_HUMAN
θ value	0.0961366 (rank : 22)	NC score	0.182389 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

MTG8_MOUSE
θ value	0.0961366 (rank : 23)	NC score	0.182801 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

HRX_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.089082 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ZMY10_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.197859 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ZMY10_MOUSE
θ value	0.163984 (rank : 26)	NC score	0.198368 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

SETD8_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.118107 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

ADAM8_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.016489 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	326	Shared Neighborhood Hits	5
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

SETD8_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.113583 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

MLL4_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.078310 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SUV91_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.091779 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV92_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.092520 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

PRDM5_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.002619 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	790	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQX1	Gene names	PRDM5, PFM2
Domain Architecture
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

SUV92_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.088886 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.087286 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

MLL3_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.048574 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	1644	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PKCB1_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.095477 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	488	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

MLL3_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.051583 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	1399	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZMY11_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.071882 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.071954 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ANKY1_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.032811 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

EHMT2_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.036266 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.035945 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	750	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EZH1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.070677 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	4.03905 (rank : 45)	NC score	0.070547 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ZMY12_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.084914 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0C1, Q5VUS6, Q8TC87, Q96M51	Gene names	ZMYND12
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 12.

PRDM5_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.000105 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXE0	Gene names	Prdm5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

WRN_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.008955 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

EZH2_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.062266 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.061864 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ADAM8_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.007641 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

KLC4_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.007073 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

NSD1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.056075 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.057350 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	472	Shared Neighborhood Hits	27
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PDCD2_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.103449 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

TRI29_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.005045 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

PDCD2_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.083210 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

ZMY15_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.050430 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

Hits sorted by NC score

SMYD3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
NC score	0.998226 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD2_HUMAN
NC score	0.916488 (rank : 3)	θ value	1.19377e-60 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

SMYD2_MOUSE
NC score	0.914099 (rank : 4)	θ value	7.73779e-60 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD1_HUMAN
NC score	0.901298 (rank : 5)	θ value	5.92465e-60 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD1_MOUSE
NC score	0.900390 (rank : 6)	θ value	6.55044e-59 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

SMYD5_HUMAN
NC score	0.532411 (rank : 7)	θ value	1.02475e-11 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

SMYD5_MOUSE
NC score	0.515489 (rank : 8)	θ value	7.34386e-10 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

SMYD4_MOUSE
NC score	0.487650 (rank : 9)	θ value	1.33837e-11 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_HUMAN
NC score	0.479963 (rank : 10)	θ value	2.28291e-11 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

ZMY19_HUMAN
NC score	0.382853 (rank : 11)	θ value	9.29e-05 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q96E35	Gene names	ZMYND19, MIZIP
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ZMY19_MOUSE
NC score	0.382853 (rank : 12)	θ value	9.29e-05 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CQG3, Q8K1T3	Gene names	Zmynd19, Mizip
Domain Architecture
Description	Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc-finger protein) (MCH-R1- interacting zinc-finger protein).

ZMY17_MOUSE
NC score	0.344497 (rank : 13)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D5Z5	Gene names	Zmynd17
Domain Architecture
Description	Zinc finger MYND domain-containing protein 17.

DEAF1_MOUSE
NC score	0.244046 (rank : 14)	θ value	0.00134147 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

DEAF1_HUMAN
NC score	0.240085 (rank : 15)	θ value	0.00175202 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	67	Shared Neighborhood Hits	26
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

MTG8R_MOUSE
NC score	0.198487 (rank : 16)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

ZMY10_MOUSE
NC score	0.198368 (rank : 17)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ZMY10_HUMAN
NC score	0.197859 (rank : 18)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	O75800, O14570, O75801, Q8N4R6, Q8NDN6	Gene names	ZMYND10, BLU
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

MTG8R_HUMAN
NC score	0.196658 (rank : 19)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	125	Shared Neighborhood Hits	29
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

EGLN1_MOUSE
NC score	0.196510 (rank : 20)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

EGLN1_HUMAN
NC score	0.192494 (rank : 21)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

ANKY2_MOUSE
NC score	0.186791 (rank : 22)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	316	Shared Neighborhood Hits	27
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

MTG8_MOUSE
NC score	0.182801 (rank : 23)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	83	Shared Neighborhood Hits	30
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

MTG8_HUMAN
NC score	0.182389 (rank : 24)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	87	Shared Neighborhood Hits	29
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

ANKY2_HUMAN
NC score	0.176284 (rank : 25)	θ value	0.00035302 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	306	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

SETD8_HUMAN
NC score	0.118107 (rank : 26)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
NC score	0.113583 (rank : 27)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	131	Shared Neighborhood Hits	22
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

PDCD2_MOUSE
NC score	0.103449 (rank : 28)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	P46718, Q8BR06	Gene names	Pdcd2, Rp8
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8).

PKCB1_HUMAN
NC score	0.095477 (rank : 29)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	488	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SUV92_HUMAN
NC score	0.092520 (rank : 30)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
NC score	0.091779 (rank : 31)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

HRX_HUMAN
NC score	0.089082 (rank : 32)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SUV92_MOUSE
NC score	0.088886 (rank : 33)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.087286 (rank : 34)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	69	Shared Neighborhood Hits	20
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

ZMY12_HUMAN
NC score	0.084914 (rank : 35)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0C1, Q5VUS6, Q8TC87, Q96M51	Gene names	ZMYND12
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 12.

PDCD2_HUMAN
NC score	0.083210 (rank : 36)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q16342, Q9UH12	Gene names	PDCD2, RP8, ZMYND7
Domain Architecture
Description	Programmed cell death protein 2 (Zinc finger protein Rp-8) (Zinc finger MYND domain-containing protein 7).

MLL4_HUMAN
NC score	0.078310 (rank : 37)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	722	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

ZMY11_MOUSE
NC score	0.071954 (rank : 38)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZMY11_HUMAN
NC score	0.071882 (rank : 39)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	201	Shared Neighborhood Hits	24
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

EZH1_HUMAN
NC score	0.070677 (rank : 40)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	121	Shared Neighborhood Hits	20
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.070547 (rank : 41)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	126	Shared Neighborhood Hits	20
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.062266 (rank : 42)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.061864 (rank : 43)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

NSD1_MOUSE
NC score	0.057350 (rank : 44)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	472	Shared Neighborhood Hits	27
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.056075 (rank : 45)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MLL3_MOUSE
NC score	0.051583 (rank : 46)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	1399	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZMY15_HUMAN
NC score	0.050430 (rank : 47)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

MLL3_HUMAN
NC score	0.048574 (rank : 48)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	1644	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EHMT2_HUMAN
NC score	0.036266 (rank : 49)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.035945 (rank : 50)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	750	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKY1_HUMAN
NC score	0.032811 (rank : 51)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ADAM8_MOUSE
NC score	0.016489 (rank : 52)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	326	Shared Neighborhood Hits	5
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

WRN_MOUSE
NC score	0.008955 (rank : 53)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

ADAM8_HUMAN
NC score	0.007641 (rank : 54)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

KLC4_MOUSE
NC score	0.007073 (rank : 55)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

TRI29_MOUSE
NC score	0.005045 (rank : 56)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	306	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

PRDM5_HUMAN
NC score	0.002619 (rank : 57)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	790	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQX1	Gene names	PRDM5, PFM2
Domain Architecture
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

PRDM5_MOUSE
NC score	0.000105 (rank : 58)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CXE0	Gene names	Prdm5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).