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Network neighborhood for query Sequence : SETD8_HUMAN

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SETD8_HUMAN
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SETD8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	3.47146e-177 (rank : 2)	NC score	0.970602 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	62
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

HRX_HUMAN
θ value	2.88119e-14 (rank : 3)	NC score	0.534760 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	52
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
θ value	7.84624e-12 (rank : 4)	NC score	0.509206 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	722	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SUV91_HUMAN
θ value	3.89403e-11 (rank : 5)	NC score	0.613933 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	6.64225e-11 (rank : 6)	NC score	0.607615 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

EZH1_HUMAN
θ value	1.47974e-10 (rank : 7)	NC score	0.611168 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	121	Shared Neighborhood Hits	25
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	1.47974e-10 (rank : 8)	NC score	0.611579 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

MLL2_HUMAN
θ value	1.47974e-10 (rank : 9)	NC score	0.391135 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1788	Shared Neighborhood Hits	54
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

EZH2_HUMAN
θ value	3.29651e-10 (rank : 10)	NC score	0.612180 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV92_HUMAN
θ value	5.62301e-10 (rank : 11)	NC score	0.607985 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH2_MOUSE
θ value	1.63604e-09 (rank : 12)	NC score	0.606824 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SETD2_HUMAN
θ value	2.13673e-09 (rank : 13)	NC score	0.561295 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	412	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SUV92_MOUSE
θ value	2.79066e-09 (rank : 14)	NC score	0.598377 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MLL3_HUMAN
θ value	2.36244e-08 (rank : 15)	NC score	0.374364 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	1644	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EHMT2_HUMAN
θ value	3.08544e-08 (rank : 16)	NC score	0.293914 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	3.08544e-08 (rank : 17)	NC score	0.293614 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MLL3_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.392623 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	1399	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SET1A_HUMAN
θ value	3.41135e-07 (rank : 19)	NC score	0.516706 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	42
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NSD1_HUMAN
θ value	9.92553e-07 (rank : 20)	NC score	0.460427 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	9.92553e-07 (rank : 21)	NC score	0.465416 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	472	Shared Neighborhood Hits	46
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

EHMT1_HUMAN
θ value	4.92598e-06 (rank : 22)	NC score	0.278975 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

BRD4_HUMAN
θ value	0.0113563 (rank : 23)	NC score	0.094707 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	851	Shared Neighborhood Hits	30
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

JHD1B_HUMAN
θ value	0.0113563 (rank : 24)	NC score	0.101376 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

BRE1B_MOUSE
θ value	0.0431538 (rank : 25)	NC score	0.064603 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	970	Shared Neighborhood Hits	25
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CJ012_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.103236 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	467	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

BRD3_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.077202 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	402	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

JHD1B_MOUSE
θ value	0.0563607 (rank : 28)	NC score	0.095260 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

SFR11_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.105780 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

BRE1B_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.060260 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	1040	Shared Neighborhood Hits	31
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

TRDN_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.103763 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	542	Shared Neighborhood Hits	27
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

H14_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.052075 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

LYRIC_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.091636 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

PRP4B_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.019087 (rank : 173)
Query Neighborhood Hits	114	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SMYD3_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.118107 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
θ value	0.21417 (rank : 36)	NC score	0.117887 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

BCL6_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.006533 (rank : 193)
Query Neighborhood Hits	114	Target Neighborhood Hits	922	Shared Neighborhood Hits	14
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

NFH_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.065347 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	2247	Shared Neighborhood Hits	75
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

APXL_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.053938 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BRD3_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.082201 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	369	Shared Neighborhood Hits	18
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

HIRP3_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.056331 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	323	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

A20A2_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.034075 (rank : 157)
Query Neighborhood Hits	114	Target Neighborhood Hits	716	Shared Neighborhood Hits	20
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

NFH_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.045120 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	1242	Shared Neighborhood Hits	51
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SETB2_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.372023 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

XYLT1_MOUSE
θ value	0.47712 (rank : 45)	NC score	0.046554 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

BRD4_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.083041 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	845	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

KCNQ3_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.018526 (rank : 174)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MKL1_MOUSE
θ value	0.813845 (rank : 48)	NC score	0.059228 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	667	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

TCF20_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.122041 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

ADDB_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.075213 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	574	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BASP_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.057477 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BCL6_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.007193 (rank : 192)
Query Neighborhood Hits	114	Target Neighborhood Hits	913	Shared Neighborhood Hits	14
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BRE1A_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.042403 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	1071	Shared Neighborhood Hits	21
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

LYRIC_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.080137 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

ATX2_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.052566 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MAP1B_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.062946 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	903	Shared Neighborhood Hits	37
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SRRM2_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.076377 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ABCF1_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.035543 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ELF4_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.015714 (rank : 179)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

KIF3A_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.016242 (rank : 177)
Query Neighborhood Hits	114	Target Neighborhood Hits	715	Shared Neighborhood Hits	22
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

RFFL_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.020346 (rank : 170)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

SFR12_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.039039 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ANK2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.055159 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	1615	Shared Neighborhood Hits	56
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

KIF3A_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.016224 (rank : 178)
Query Neighborhood Hits	114	Target Neighborhood Hits	704	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MAP1B_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.056823 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	977	Shared Neighborhood Hits	38
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NEUM_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.048450 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

TITIN_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.014922 (rank : 181)
Query Neighborhood Hits	114	Target Neighborhood Hits	2923	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ACM1_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.002907 (rank : 197)
Query Neighborhood Hits	114	Target Neighborhood Hits	908	Shared Neighborhood Hits	3
SwissProt Accessions	P11229	Gene names	CHRM1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ACM1_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.002720 (rank : 198)
Query Neighborhood Hits	114	Target Neighborhood Hits	917	Shared Neighborhood Hits	3
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

BRE1A_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.038566 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	1025	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CNGA1_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.018231 (rank : 176)
Query Neighborhood Hits	114	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

HAP28_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.035688 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q13442, Q92906	Gene names	PDAP1, HASPP28
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

HMMR_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.020036 (rank : 171)
Query Neighborhood Hits	114	Target Neighborhood Hits	1178	Shared Neighborhood Hits	34
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

SRRM2_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.065351 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SYNJ1_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.041866 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ARS2_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.023325 (rank : 168)
Query Neighborhood Hits	114	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CYLC2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.045122 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	13
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

MKL1_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.036797 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

MYH11_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.009936 (rank : 190)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	37
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NADAP_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.039250 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NEK1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.001625 (rank : 200)
Query Neighborhood Hits	114	Target Neighborhood Hits	1129	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PHF20_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.080457 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

SCYB9_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.030510 (rank : 161)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q07325, Q503B4	Gene names	CXCL9, MIG, SCYB9
Domain Architecture
Description	Small inducible cytokine B9 precursor (CXCL9) (Gamma interferon- induced monokine) (MIG).

TCF20_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.112448 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

CCD82_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.018261 (rank : 175)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

H12_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.032797 (rank : 159)
Query Neighborhood Hits	114	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

H13_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.034045 (rank : 158)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

HNF1A_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.024524 (rank : 167)
Query Neighborhood Hits	114	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

HUCE1_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.046867 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

MAGD4_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.012763 (rank : 186)
Query Neighborhood Hits	114	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

RRBP1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.029602 (rank : 163)
Query Neighborhood Hits	114	Target Neighborhood Hits	1306	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

SFR12_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.037702 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	486	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SIA7A_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.026001 (rank : 165)
Query Neighborhood Hits	114	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

CAF1A_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.025261 (rank : 166)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	21
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCNL2_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.014533 (rank : 182)
Query Neighborhood Hits	114	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

CDT1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.022730 (rank : 169)
Query Neighborhood Hits	114	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

DDX21_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.008294 (rank : 191)
Query Neighborhood Hits	114	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

KCNB1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.005717 (rank : 194)
Query Neighborhood Hits	114	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KI21A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.015530 (rank : 180)
Query Neighborhood Hits	114	Target Neighborhood Hits	1543	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

RERE_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.032343 (rank : 160)
Query Neighborhood Hits	114	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ROBO1_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.002474 (rank : 199)
Query Neighborhood Hits	114	Target Neighborhood Hits	529	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

SMYD1_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.047960 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD4_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.030505 (rank : 162)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

TAF3_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.052460 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	463	Shared Neighborhood Hits	23
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TCEA3_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.010430 (rank : 189)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O75764	Gene names	TCEA3, TFIISH
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

CHD2_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.012897 (rank : 184)
Query Neighborhood Hits	114	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CING_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.019954 (rank : 172)
Query Neighborhood Hits	114	Target Neighborhood Hits	1432	Shared Neighborhood Hits	39
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CKAP5_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.027016 (rank : 164)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

MAFF_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.012774 (rank : 185)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAFF_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.012943 (rank : 183)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

MINK1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.005669 (rank : 195)
Query Neighborhood Hits	114	Target Neighborhood Hits	1477	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.004466 (rank : 196)
Query Neighborhood Hits	114	Target Neighborhood Hits	1451	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

PRP4B_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.010557 (rank : 188)
Query Neighborhood Hits	114	Target Neighborhood Hits	1030	Shared Neighborhood Hits	21
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

STK10_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.010568 (rank : 187)
Query Neighborhood Hits	114	Target Neighborhood Hits	2132	Shared Neighborhood Hits	50
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

AIRE_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.058454 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.062034 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BASP_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.052575 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.061110 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	693	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.070725 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.062554 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.053930 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	780	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.053026 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	744	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.052113 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	803	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.075959 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.052502 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRDT_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.055062 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.060711 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.060711 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.062227 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.062841 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.059129 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.058415 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CXCC1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.056387 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.055921 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DNMT1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.052689 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DPF1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.075299 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.068188 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.069741 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	388	Shared Neighborhood Hits	44
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FXL19_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.060722 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.060235 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

IWS1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.062534 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	55
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.066797 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	1258	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD1A_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.054748 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.055073 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

K1333_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.074389 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.074954 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LAD1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.099161 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	441	Shared Neighborhood Hits	35
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MAP1A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.053771 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	62
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MBB1A_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.050721 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	665	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.062971 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.054307 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MDC1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.077354 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	1446	Shared Neighborhood Hits	56
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.066871 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MPP8_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.066402 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	948	Shared Neighborhood Hits	50
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYST3_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.063351 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	25
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.063403 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	688	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.069589 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	671	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.063262 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	416	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NACAM_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.064205 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	1866	Shared Neighborhood Hits	51
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NIPBL_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.066668 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	1311	Shared Neighborhood Hits	65
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.066735 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	60
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PCLO_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.051683 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	2046	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PF21A_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.059010 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.058442 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	285	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.052905 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.088937 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.087043 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.129986 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.050329 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.050020 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.068252 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF6_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.098429 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.095700 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.072840 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.068996 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PKCB1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.069487 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	488	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RAI1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.099934 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	360	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.103576 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBBP6_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.054893 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.054222 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	1014	Shared Neighborhood Hits	51
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REQU_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.067398 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	523	Shared Neighborhood Hits	12
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.066421 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	519	Shared Neighborhood Hits	10
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.061715 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	539	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SELPL_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.051745 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	588	Shared Neighborhood Hits	30
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SETB1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.308985 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.312043 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD7_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.075485 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.075313 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SRRM1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.056249 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.064837 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	966	Shared Neighborhood Hits	37
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF3_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051798 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	568	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARSH_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.051153 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	768	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TGON2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.065915 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	46
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.079694 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND2_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.064187 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	828	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UHRF1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.053708 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.058987 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.056562 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.053537 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZCPW1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.054381 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

Hits sorted by NC score

SETD8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
NC score	0.970602 (rank : 2)	θ value	3.47146e-177 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	62
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SUV91_HUMAN
NC score	0.613933 (rank : 3)	θ value	3.89403e-11 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

EZH2_HUMAN
NC score	0.612180 (rank : 4)	θ value	3.29651e-10 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_MOUSE
NC score	0.611579 (rank : 5)	θ value	1.47974e-10 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	26
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_HUMAN
NC score	0.611168 (rank : 6)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	121	Shared Neighborhood Hits	25
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SUV92_HUMAN
NC score	0.607985 (rank : 7)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.607615 (rank : 8)	θ value	6.64225e-11 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

EZH2_MOUSE
NC score	0.606824 (rank : 9)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV92_MOUSE
NC score	0.598377 (rank : 10)	θ value	2.79066e-09 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SETD2_HUMAN
NC score	0.561295 (rank : 11)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	412	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HRX_HUMAN
NC score	0.534760 (rank : 12)	θ value	2.88119e-14 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	825	Shared Neighborhood Hits	52
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SET1A_HUMAN
NC score	0.516706 (rank : 13)	θ value	3.41135e-07 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	42
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MLL4_HUMAN
NC score	0.509206 (rank : 14)	θ value	7.84624e-12 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	722	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NSD1_MOUSE
NC score	0.465416 (rank : 15)	θ value	9.92553e-07 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	472	Shared Neighborhood Hits	46
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.460427 (rank : 16)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	37
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MLL3_MOUSE
NC score	0.392623 (rank : 17)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1399	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.391135 (rank : 18)	θ value	1.47974e-10 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	1788	Shared Neighborhood Hits	54
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.374364 (rank : 19)	θ value	2.36244e-08 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	1644	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETB2_HUMAN
NC score	0.372023 (rank : 20)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.312043 (rank : 21)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	114	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.308985 (rank : 22)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	114	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

EHMT2_HUMAN
NC score	0.293914 (rank : 23)	θ value	3.08544e-08 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	498	Shared Neighborhood Hits	31
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.293614 (rank : 24)	θ value	3.08544e-08 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.278975 (rank : 25)	θ value	4.92598e-06 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

PHF11_HUMAN
NC score	0.129986 (rank : 26)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	114	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TCF20_HUMAN
NC score	0.122041 (rank : 27)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

SMYD3_HUMAN
NC score	0.118107 (rank : 28)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
NC score	0.117887 (rank : 29)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TCF20_MOUSE
NC score	0.112448 (rank : 30)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	396	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SFR11_HUMAN
NC score	0.105780 (rank : 31)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TRDN_HUMAN
NC score	0.103763 (rank : 32)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	542	Shared Neighborhood Hits	27
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

RAI1_MOUSE
NC score	0.103576 (rank : 33)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	114	Target Neighborhood Hits	344	Shared Neighborhood Hits	23
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CJ012_HUMAN
NC score	0.103236 (rank : 34)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	467	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

JHD1B_HUMAN
NC score	0.101376 (rank : 35)	θ value	0.0113563 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

RAI1_HUMAN
NC score	0.099934 (rank : 36)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	114	Target Neighborhood Hits	360	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

LAD1_HUMAN
NC score	0.099161 (rank : 37)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	114	Target Neighborhood Hits	441	Shared Neighborhood Hits	35
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PHF6_HUMAN
NC score	0.098429 (rank : 38)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
NC score	0.095700 (rank : 39)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

JHD1B_MOUSE
NC score	0.095260 (rank : 40)	θ value	0.0563607 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	214	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

BRD4_HUMAN
NC score	0.094707 (rank : 41)	θ value	0.0113563 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	851	Shared Neighborhood Hits	30
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

LYRIC_MOUSE
NC score	0.091636 (rank : 42)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	126	Shared Neighborhood Hits	11
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

PHF10_HUMAN
NC score	0.088937 (rank : 43)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	114	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.087043 (rank : 44)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	114	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

BRD4_MOUSE
NC score	0.083041 (rank : 45)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	845	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD3_HUMAN
NC score	0.082201 (rank : 46)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	369	Shared Neighborhood Hits	18
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

PHF20_MOUSE
NC score	0.080457 (rank : 47)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	513	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

LYRIC_HUMAN
NC score	0.080137 (rank : 48)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

TXND2_HUMAN
NC score	0.079694 (rank : 49)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	114	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MDC1_HUMAN
NC score	0.077354 (rank : 50)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	114	Target Neighborhood Hits	1446	Shared Neighborhood Hits	56
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

BRD3_MOUSE
NC score	0.077202 (rank : 51)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	402	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

SRRM2_HUMAN
NC score	0.076377 (rank : 52)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	1296	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

BPTF_HUMAN
NC score	0.075959 (rank : 53)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	114	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SETD7_HUMAN
NC score	0.075485 (rank : 54)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
NC score	0.075313 (rank : 55)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

DPF1_HUMAN
NC score	0.075299 (rank : 56)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

ADDB_MOUSE
NC score	0.075213 (rank : 57)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	574	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

K1333_MOUSE
NC score	0.074954 (rank : 58)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_HUMAN
NC score	0.074389 (rank : 59)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF7_HUMAN
NC score	0.072840 (rank : 60)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	114	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

BAZ1B_HUMAN
NC score	0.070725 (rank : 61)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

ELOA1_HUMAN
NC score	0.069741 (rank : 62)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	114	Target Neighborhood Hits	388	Shared Neighborhood Hits	44
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

MYST4_HUMAN
NC score	0.069589 (rank : 63)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	114	Target Neighborhood Hits	671	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PKCB1_HUMAN
NC score	0.069487 (rank : 64)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	114	Target Neighborhood Hits	488	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PHF7_MOUSE
NC score	0.068996 (rank : 65)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF20_HUMAN
NC score	0.068252 (rank : 66)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

DPF1_MOUSE
NC score	0.068188 (rank : 67)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	114	Target Neighborhood Hits	491	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.067398 (rank : 68)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	114	Target Neighborhood Hits	523	Shared Neighborhood Hits	12
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

MDC1_MOUSE
NC score	0.066871 (rank : 69)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	114	Target Neighborhood Hits	998	Shared Neighborhood Hits	42
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

IWS1_MOUSE
NC score	0.066797 (rank : 70)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	114	Target Neighborhood Hits	1258	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NPBL_MOUSE
NC score	0.066735 (rank : 71)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	114	Target Neighborhood Hits	1041	Shared Neighborhood Hits	60
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.066668 (rank : 72)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	114	Target Neighborhood Hits	1311	Shared Neighborhood Hits	65
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

REQU_MOUSE
NC score	0.066421 (rank : 73)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	114	Target Neighborhood Hits	519	Shared Neighborhood Hits	10
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

MPP8_HUMAN
NC score	0.066402 (rank : 74)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	114	Target Neighborhood Hits	948	Shared Neighborhood Hits	50
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TGON2_HUMAN
NC score	0.065915 (rank : 75)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	114	Target Neighborhood Hits	1037	Shared Neighborhood Hits	46
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SRRM2_MOUSE
NC score	0.065351 (rank : 76)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	1470	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_MOUSE
NC score	0.065347 (rank : 77)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	2247	Shared Neighborhood Hits	75
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRRM1_MOUSE
NC score	0.064837 (rank : 78)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	114	Target Neighborhood Hits	966	Shared Neighborhood Hits	37
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BRE1B_MOUSE
NC score	0.064603 (rank : 79)	θ value	0.0431538 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	970	Shared Neighborhood Hits	25
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

NACAM_MOUSE
NC score	0.064205 (rank : 80)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	114	Target Neighborhood Hits	1866	Shared Neighborhood Hits	51
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TXND2_MOUSE
NC score	0.064187 (rank : 81)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	114	Target Neighborhood Hits	828	Shared Neighborhood Hits	51
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

MYST3_MOUSE
NC score	0.063403 (rank : 82)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	114	Target Neighborhood Hits	688	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST3_HUMAN
NC score	0.063351 (rank : 83)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	114	Target Neighborhood Hits	772	Shared Neighborhood Hits	25
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST4_MOUSE
NC score	0.063262 (rank : 84)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	114	Target Neighborhood Hits	416	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

MBD1_HUMAN
NC score	0.062971 (rank : 85)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	114	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MAP1B_HUMAN
NC score	0.062946 (rank : 86)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	903	Shared Neighborhood Hits	37
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

CBX3_MOUSE
NC score	0.062841 (rank : 87)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	114	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

BAZ1B_MOUSE
NC score	0.062554 (rank : 88)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	394	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

IWS1_HUMAN
NC score	0.062534 (rank : 89)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	114	Target Neighborhood Hits	1241	Shared Neighborhood Hits	55
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CBX3_HUMAN
NC score	0.062227 (rank : 90)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	114	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

AIRE_MOUSE
NC score	0.062034 (rank : 91)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

RSF1_HUMAN
NC score	0.061715 (rank : 92)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	114	Target Neighborhood Hits	539	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BAZ1A_HUMAN
NC score	0.061110 (rank : 93)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	693	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

FXL19_HUMAN
NC score	0.060722 (rank : 94)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

CBX1_HUMAN
NC score	0.060711 (rank : 95)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.060711 (rank : 96)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	114	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

BRE1B_HUMAN
NC score	0.060260 (rank : 97)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	1040	Shared Neighborhood Hits	31
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

FXL19_MOUSE
NC score	0.060235 (rank : 98)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	114	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

MKL1_MOUSE
NC score	0.059228 (rank : 99)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	667	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CBX5_HUMAN
NC score	0.059129 (rank : 100)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

PF21A_HUMAN
NC score	0.059010 (rank : 101)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	114	Target Neighborhood Hits	303	Shared Neighborhood Hits	14
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

UHRF1_MOUSE
NC score	0.058987 (rank : 102)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	114	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

AIRE_HUMAN
NC score	0.058454 (rank : 103)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

PF21A_MOUSE
NC score	0.058442 (rank : 104)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	114	Target Neighborhood Hits	285	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CBX5_MOUSE
NC score	0.058415 (rank : 105)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	114	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

BASP_MOUSE
NC score	0.057477 (rank : 106)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MAP1B_MOUSE
NC score	0.056823 (rank : 107)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	977	Shared Neighborhood Hits	38
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

UHRF2_HUMAN
NC score	0.056562 (rank : 108)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	114	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

CXCC1_HUMAN
NC score	0.056387 (rank : 109)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

HIRP3_HUMAN
NC score	0.056331 (rank : 110)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	323	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

SRRM1_HUMAN
NC score	0.056249 (rank : 111)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	114	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

CXCC1_MOUSE
NC score	0.055921 (rank : 112)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

ANK2_HUMAN
NC score	0.055159 (rank : 113)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	1615	Shared Neighborhood Hits	56
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

JHD1A_MOUSE
NC score	0.055073 (rank : 114)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	10
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

BRDT_MOUSE
NC score	0.055062 (rank : 115)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	114	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

RBBP6_HUMAN
NC score	0.054893 (rank : 116)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

JHD1A_HUMAN
NC score	0.054748 (rank : 117)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	114	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

ZCPW1_MOUSE
NC score	0.054381 (rank : 118)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	114	Target Neighborhood Hits	307	Shared Neighborhood Hits	27
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

MBD1_MOUSE
NC score	0.054307 (rank : 119)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

RBBP6_MOUSE
NC score	0.054222 (rank : 120)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	114	Target Neighborhood Hits	1014	Shared Neighborhood Hits	51
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

APXL_HUMAN
NC score	0.053938 (rank : 121)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	20
SwissProt Accessions	Q13796	Gene names	APXL
Domain Architecture
Description	Apical-like protein (Protein APXL).

BAZ2A_HUMAN
NC score	0.053930 (rank : 122)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	780	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MAP1A_HUMAN
NC score	0.053771 (rank : 123)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	114	Target Neighborhood Hits	1626	Shared Neighborhood Hits	62
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

UHRF1_HUMAN
NC score	0.053708 (rank : 124)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	114	Target Neighborhood Hits	272	Shared Neighborhood Hits	12
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF2_MOUSE
NC score	0.053537 (rank : 125)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BAZ2A_MOUSE
NC score	0.053026 (rank : 126)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	114	Target Neighborhood Hits	744	Shared Neighborhood Hits	39
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PF21B_MOUSE
NC score	0.052905 (rank : 127)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	114	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

DNMT1_HUMAN
NC score	0.052689 (rank : 128)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

BASP_HUMAN
NC score	0.052575 (rank : 129)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	321	Shared Neighborhood Hits	18
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ATX2_MOUSE
NC score	0.052566 (rank : 130)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	445	Shared Neighborhood Hits	20
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BRD2_HUMAN
NC score	0.052502 (rank : 131)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	114	Target Neighborhood Hits	242	Shared Neighborhood Hits	14
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

TAF3_MOUSE
NC score	0.052460 (rank : 132)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	463	Shared Neighborhood Hits	23
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BAZ2B_HUMAN
NC score	0.052113 (rank : 133)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	114	Target Neighborhood Hits	803	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

H14_HUMAN
NC score	0.052075 (rank : 134)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

TAF3_HUMAN
NC score	0.051798 (rank : 135)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	114	Target Neighborhood Hits	568	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SELPL_MOUSE
NC score	0.051745 (rank : 136)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	114	Target Neighborhood Hits	588	Shared Neighborhood Hits	30
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PCLO_HUMAN
NC score	0.051683 (rank : 137)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	114	Target Neighborhood Hits	2046	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TARSH_HUMAN
NC score	0.051153 (rank : 138)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	114	Target Neighborhood Hits	768	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MBB1A_HUMAN
NC score	0.050721 (rank : 139)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	114	Target Neighborhood Hits	665	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PHF12_HUMAN
NC score	0.050329 (rank : 140)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	114	Target Neighborhood Hits	174	Shared Neighborhood Hits	12
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.050020 (rank : 141)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	114	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

NEUM_MOUSE
NC score	0.048450 (rank : 142)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	149	Shared Neighborhood Hits	12
SwissProt Accessions	P06837	Gene names	Gap43, Basp2
Domain Architecture
Description	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Calmodulin-binding protein P-57).

SMYD1_HUMAN
NC score	0.047960 (rank : 143)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

HUCE1_HUMAN
NC score	0.046867 (rank : 144)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

XYLT1_MOUSE
NC score	0.046554 (rank : 145)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

CYLC2_HUMAN
NC score	0.045122 (rank : 146)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	13
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

NFH_HUMAN
NC score	0.045120 (rank : 147)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	1242	Shared Neighborhood Hits	51
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BRE1A_HUMAN
NC score	0.042403 (rank : 148)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	1071	Shared Neighborhood Hits	21
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

SYNJ1_HUMAN
NC score	0.041866 (rank : 149)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	498	Shared Neighborhood Hits	21
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

NADAP_HUMAN
NC score	0.039250 (rank : 150)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	208	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

SFR12_HUMAN
NC score	0.039039 (rank : 151)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	553	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

BRE1A_MOUSE
NC score	0.038566 (rank : 152)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	1025	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

SFR12_MOUSE
NC score	0.037702 (rank : 153)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	486	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

MKL1_HUMAN
NC score	0.036797 (rank : 154)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q969V6, Q8TCL1, Q96SC5, Q96SC6, Q9P2B0	Gene names	MKL1, KIAA1438, MAL
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein).

HAP28_HUMAN
NC score	0.035688 (rank : 155)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q13442, Q92906	Gene names	PDAP1, HASPP28
Domain Architecture	No domain graphic available
Description	28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).

ABCF1_HUMAN
NC score	0.035543 (rank : 156)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

A20A2_HUMAN
NC score	0.034075 (rank : 157)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	716	Shared Neighborhood Hits	20
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

H13_MOUSE
NC score	0.034045 (rank : 158)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P43277, Q8C6M4	Gene names	Hist1h1d, H1f3
Domain Architecture
Description	Histone H1.3 (H1 VAR.4) (H1d).

H12_MOUSE
NC score	0.032797 (rank : 159)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	52	Shared Neighborhood Hits	9
SwissProt Accessions	P15864	Gene names	Hist1h1c, H1f2
Domain Architecture
Description	Histone H1.2 (H1 VAR.1) (H1c).

RERE_MOUSE
NC score	0.032343 (rank : 160)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SCYB9_HUMAN
NC score	0.030510 (rank : 161)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q07325, Q503B4	Gene names	CXCL9, MIG, SCYB9
Domain Architecture
Description	Small inducible cytokine B9 precursor (CXCL9) (Gamma interferon- induced monokine) (MIG).

SMYD4_HUMAN
NC score	0.030505 (rank : 162)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

RRBP1_HUMAN
NC score	0.029602 (rank : 163)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	1306	Shared Neighborhood Hits	48
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

CKAP5_HUMAN
NC score	0.027016 (rank : 164)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

SIA7A_MOUSE
NC score	0.026001 (rank : 165)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	203	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

CAF1A_HUMAN
NC score	0.025261 (rank : 166)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	750	Shared Neighborhood Hits	21
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

HNF1A_HUMAN
NC score	0.024524 (rank : 167)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

ARS2_MOUSE
NC score	0.023325 (rank : 168)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

CDT1_HUMAN
NC score	0.022730 (rank : 169)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H211, Q86XX9, Q96CJ5, Q96GK5, Q96H67, Q96HE6, Q9BWM0	Gene names	CDT1
Domain Architecture	No domain graphic available
Description	DNA replication factor Cdt1 (Double parked homolog) (DUP).

RFFL_HUMAN
NC score	0.020346 (rank : 170)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

HMMR_MOUSE
NC score	0.020036 (rank : 171)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	1178	Shared Neighborhood Hits	34
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CING_MOUSE
NC score	0.019954 (rank : 172)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	1432	Shared Neighborhood Hits	39
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

PRP4B_MOUSE
NC score	0.019087 (rank : 173)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

KCNQ3_HUMAN
NC score	0.018526 (rank : 174)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

CCD82_HUMAN
NC score	0.018261 (rank : 175)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4S0, Q9H2Q5, Q9H5E3	Gene names	CCDC82
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 82.

CNGA1_MOUSE
NC score	0.018231 (rank : 176)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

KIF3A_MOUSE
NC score	0.016242 (rank : 177)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	715	Shared Neighborhood Hits	22
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_HUMAN
NC score	0.016224 (rank : 178)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	704	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

ELF4_HUMAN
NC score	0.015714 (rank : 179)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

KI21A_HUMAN
NC score	0.015530 (rank : 180)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	1543	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

TITIN_HUMAN
NC score	0.014922 (rank : 181)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	2923	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CCNL2_HUMAN
NC score	0.014533 (rank : 182)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

MAFF_MOUSE
NC score	0.012943 (rank : 183)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O54791	Gene names	Maff
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F).

CHD2_HUMAN
NC score	0.012897 (rank : 184)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

MAFF_HUMAN
NC score	0.012774 (rank : 185)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULX9, Q9Y525	Gene names	MAFF
Domain Architecture
Description	Transcription factor MafF (V-maf musculoaponeurotic fibrosarcoma oncogene homolog F) (U-Maf).

MAGD4_HUMAN
NC score	0.012763 (rank : 186)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	338	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

STK10_MOUSE
NC score	0.010568 (rank : 187)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	2132	Shared Neighborhood Hits	50
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

PRP4B_HUMAN
NC score	0.010557 (rank : 188)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	1030	Shared Neighborhood Hits	21
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TCEA3_HUMAN
NC score	0.010430 (rank : 189)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	O75764	Gene names	TCEA3, TFIISH
Domain Architecture
Description	Transcription elongation factor A protein 3 (Transcription elongation factor S-II protein 3) (Transcription elongation factor TFIIS.h).

MYH11_MOUSE
NC score	0.009936 (rank : 190)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	37
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

DDX21_MOUSE
NC score	0.008294 (rank : 191)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

BCL6_MOUSE
NC score	0.007193 (rank : 192)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	913	Shared Neighborhood Hits	14
SwissProt Accessions	P41183, Q61065	Gene names	Bcl6, Bcl-6
Domain Architecture
Description	B-cell lymphoma 6 protein homolog.

BCL6_HUMAN
NC score	0.006533 (rank : 193)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	922	Shared Neighborhood Hits	14
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

KCNB1_HUMAN
NC score	0.005717 (rank : 194)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

MINK1_HUMAN
NC score	0.005669 (rank : 195)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	1477	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
NC score	0.004466 (rank : 196)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	1451	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ACM1_HUMAN
NC score	0.002907 (rank : 197)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	908	Shared Neighborhood Hits	3
SwissProt Accessions	P11229	Gene names	CHRM1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ACM1_MOUSE
NC score	0.002720 (rank : 198)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	917	Shared Neighborhood Hits	3
SwissProt Accessions	P12657, Q8BJN3	Gene names	Chrm1, Chrm-1
Domain Architecture
Description	Muscarinic acetylcholine receptor M1.

ROBO1_HUMAN
NC score	0.002474 (rank : 199)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	529	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

NEK1_HUMAN
NC score	0.001625 (rank : 200)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	1129	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).