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Network neighborhood for query Sequence : SUV91_MOUSE

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SUV91_MOUSE
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SUV91_HUMAN
θ value	0 (rank : 1)	NC score	0.998234 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	61
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
θ value	4.14853e-138 (rank : 3)	NC score	0.986798 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	5.6069e-135 (rank : 4)	NC score	0.986722 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	59	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EHMT1_HUMAN
θ value	3.73686e-38 (rank : 5)	NC score	0.410262 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	417	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
θ value	4.568e-36 (rank : 6)	NC score	0.419584 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	5.96599e-36 (rank : 7)	NC score	0.416031 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EZH1_HUMAN
θ value	2.43343e-21 (rank : 8)	NC score	0.696594 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	2.43343e-21 (rank : 9)	NC score	0.695620 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	2.06002e-20 (rank : 10)	NC score	0.695477 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SETB1_MOUSE
θ value	5.99374e-20 (rank : 11)	NC score	0.646271 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD2_HUMAN
θ value	7.82807e-20 (rank : 12)	NC score	0.669852 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EZH2_MOUSE
θ value	1.02238e-19 (rank : 13)	NC score	0.689892 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SETB1_HUMAN
θ value	1.33526e-19 (rank : 14)	NC score	0.643508 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

NSD1_MOUSE
θ value	1.47631e-18 (rank : 15)	NC score	0.567804 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
θ value	7.32683e-18 (rank : 16)	NC score	0.569301 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

HRX_HUMAN
θ value	8.95645e-16 (rank : 17)	NC score	0.529043 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL2_HUMAN
θ value	1.42992e-13 (rank : 18)	NC score	0.394799 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	1788	Shared Neighborhood Hits	30
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL4_HUMAN
θ value	1.86753e-13 (rank : 19)	NC score	0.510388 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL3_HUMAN
θ value	1.58096e-12 (rank : 20)	NC score	0.376601 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	1644	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	2.0648e-12 (rank : 21)	NC score	0.396042 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SETB2_HUMAN
θ value	6.00763e-12 (rank : 22)	NC score	0.651321 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SET1A_HUMAN
θ value	1.02475e-11 (rank : 23)	NC score	0.564982 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
θ value	6.64225e-11 (rank : 24)	NC score	0.607615 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	6.64225e-11 (rank : 25)	NC score	0.607780 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

CBX5_HUMAN
θ value	5.81887e-07 (rank : 26)	NC score	0.390113 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	5.81887e-07 (rank : 27)	NC score	0.389409 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

MPP8_HUMAN
θ value	3.77169e-06 (rank : 28)	NC score	0.177657 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CBX1_HUMAN
θ value	4.92598e-06 (rank : 29)	NC score	0.399762 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	4.92598e-06 (rank : 30)	NC score	0.399762 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_MOUSE
θ value	4.92598e-06 (rank : 31)	NC score	0.399434 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX3_HUMAN
θ value	6.43352e-06 (rank : 32)	NC score	0.398452 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX2_HUMAN
θ value	1.43324e-05 (rank : 33)	NC score	0.311560 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	264	Shared Neighborhood Hits	30
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX2_MOUSE
θ value	1.43324e-05 (rank : 34)	NC score	0.331364 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	30
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX4_HUMAN
θ value	0.00020696 (rank : 35)	NC score	0.312582 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	0.00035302 (rank : 36)	NC score	0.309889 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX7_MOUSE
θ value	0.00035302 (rank : 37)	NC score	0.355276 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX6_HUMAN
θ value	0.000461057 (rank : 38)	NC score	0.309868 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	0.000461057 (rank : 39)	NC score	0.310013 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CDY1_HUMAN
θ value	0.000786445 (rank : 40)	NC score	0.222111 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.221594 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CBX7_HUMAN
θ value	0.00102713 (rank : 42)	NC score	0.337890 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CDYL1_HUMAN
θ value	0.00134147 (rank : 43)	NC score	0.219226 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL2_HUMAN
θ value	0.00134147 (rank : 44)	NC score	0.233279 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CBX8_HUMAN
θ value	0.00175202 (rank : 45)	NC score	0.309895 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	0.00175202 (rank : 46)	NC score	0.306213 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CDYL_MOUSE
θ value	0.00298849 (rank : 47)	NC score	0.217622 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

F107A_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.070840 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O95990, Q96NH4	Gene names	FAM107A, DRR1, TU3A
Domain Architecture
Description	Protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A).

SETD7_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.143442 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.144683 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

CHD1_HUMAN
θ value	0.62314 (rank : 51)	NC score	0.069698 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.069587 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SMYD3_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.087857 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.087286 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

CHD9_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.038705 (rank : 98)
Query Neighborhood Hits	69	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.039052 (rank : 97)
Query Neighborhood Hits	69	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD6_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.039492 (rank : 96)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

F107B_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.034843 (rank : 99)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

CHD2_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.068973 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

DNJC7_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.008928 (rank : 102)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

CHD8_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.032087 (rank : 100)
Query Neighborhood Hits	69	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

F107B_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.030589 (rank : 101)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

KCC1A_HUMAN
θ value	6.88961 (rank : 63)	NC score	-0.004016 (rank : 107)
Query Neighborhood Hits	69	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

SEP10_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.004896 (rank : 104)
Query Neighborhood Hits	69	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

CROCC_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.000436 (rank : 106)
Query Neighborhood Hits	69	Target Neighborhood Hits	1460	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DNJC7_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.007102 (rank : 103)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

KCC1A_MOUSE
θ value	8.99809 (rank : 67)	NC score	-0.004169 (rank : 108)
Query Neighborhood Hits	69	Target Neighborhood Hits	845	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

SEP10_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.004491 (rank : 105)
Query Neighborhood Hits	69	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

ZN443_HUMAN
θ value	8.99809 (rank : 69)	NC score	-0.004628 (rank : 109)
Query Neighborhood Hits	69	Target Neighborhood Hits	759	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2A4	Gene names	ZNF443
Domain Architecture
Description	Zinc finger protein 443 (Krueppel-type zinc finger protein ZK1).

AIRE_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.058900 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.058703 (rank : 75)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

ANKR6_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.052356 (rank : 88)
Query Neighborhood Hits	69	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKY2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.054520 (rank : 82)
Query Neighborhood Hits	69	Target Neighborhood Hits	306	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANKY2_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.053540 (rank : 86)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR22_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.060654 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR49_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.051281 (rank : 92)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR49_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.053807 (rank : 85)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

CHD3_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.067536 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	397	Shared Neighborhood Hits	38
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.063008 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	365	Shared Neighborhood Hits	32
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.062578 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.065554 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	349	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CLPB_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.050813 (rank : 93)
Query Neighborhood Hits	69	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DPF1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.063894 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.055989 (rank : 77)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

INVS_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.052685 (rank : 87)
Query Neighborhood Hits	69	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

K1333_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.055190 (rank : 80)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.055561 (rank : 79)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MYST4_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.054275 (rank : 83)
Query Neighborhood Hits	69	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050295 (rank : 95)
Query Neighborhood Hits	69	Target Neighborhood Hits	416	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NUD12_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.050415 (rank : 94)
Query Neighborhood Hits	69	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

PECI_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.064253 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.063943 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

PF21A_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.051613 (rank : 91)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.051761 (rank : 90)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PHF10_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.072175 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.070550 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.097091 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF6_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.074879 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.072702 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.062540 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.057732 (rank : 76)
Query Neighborhood Hits	69	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RAI1_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.068999 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.076757 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.055568 (rank : 78)
Query Neighborhood Hits	69	Target Neighborhood Hits	523	Shared Neighborhood Hits	8
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.055148 (rank : 81)
Query Neighborhood Hits	69	Target Neighborhood Hits	519	Shared Neighborhood Hits	8
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RFXK_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.053923 (rank : 84)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

RFXK_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.052268 (rank : 89)
Query Neighborhood Hits	69	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

TCF20_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.070149 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	323	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.065247 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

Hits sorted by NC score

SUV91_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV91_HUMAN
NC score	0.998234 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	61
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV92_HUMAN
NC score	0.986798 (rank : 3)	θ value	4.14853e-138 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.986722 (rank : 4)	θ value	5.6069e-135 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	59	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH1_HUMAN
NC score	0.696594 (rank : 5)	θ value	2.43343e-21 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.695620 (rank : 6)	θ value	2.43343e-21 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.695477 (rank : 7)	θ value	2.06002e-20 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.689892 (rank : 8)	θ value	1.02238e-19 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	86	Shared Neighborhood Hits	28
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SETD2_HUMAN
NC score	0.669852 (rank : 9)	θ value	7.82807e-20 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	412	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETB2_HUMAN
NC score	0.651321 (rank : 10)	θ value	6.00763e-12 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.646271 (rank : 11)	θ value	5.99374e-20 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.643508 (rank : 12)	θ value	1.33526e-19 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	141	Shared Neighborhood Hits	24
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD8_MOUSE
NC score	0.607780 (rank : 13)	θ value	6.64225e-11 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.607615 (rank : 14)	θ value	6.64225e-11 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

NSD1_HUMAN
NC score	0.569301 (rank : 15)	θ value	7.32683e-18 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	427	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
NC score	0.567804 (rank : 16)	θ value	1.47631e-18 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SET1A_HUMAN
NC score	0.564982 (rank : 17)	θ value	1.02475e-11 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

HRX_HUMAN
NC score	0.529043 (rank : 18)	θ value	8.95645e-16 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
NC score	0.510388 (rank : 19)	θ value	1.86753e-13 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EHMT2_HUMAN
NC score	0.419584 (rank : 20)	θ value	4.568e-36 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.416031 (rank : 21)	θ value	5.96599e-36 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	750	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.410262 (rank : 22)	θ value	3.73686e-38 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	417	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

CBX1_HUMAN
NC score	0.399762 (rank : 23)	θ value	4.92598e-06 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.399762 (rank : 24)	θ value	4.92598e-06 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_MOUSE
NC score	0.399434 (rank : 25)	θ value	4.92598e-06 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX3_HUMAN
NC score	0.398452 (rank : 26)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

MLL3_MOUSE
NC score	0.396042 (rank : 27)	θ value	2.0648e-12 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.394799 (rank : 28)	θ value	1.42992e-13 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	1788	Shared Neighborhood Hits	30
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CBX5_HUMAN
NC score	0.390113 (rank : 29)	θ value	5.81887e-07 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
NC score	0.389409 (rank : 30)	θ value	5.81887e-07 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

MLL3_HUMAN
NC score	0.376601 (rank : 31)	θ value	1.58096e-12 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	1644	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CBX7_MOUSE
NC score	0.355276 (rank : 32)	θ value	0.00035302 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_HUMAN
NC score	0.337890 (rank : 33)	θ value	0.00102713 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX2_MOUSE
NC score	0.331364 (rank : 34)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	30
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX4_HUMAN
NC score	0.312582 (rank : 35)	θ value	0.00020696 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX2_HUMAN
NC score	0.311560 (rank : 36)	θ value	1.43324e-05 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	264	Shared Neighborhood Hits	30
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX6_MOUSE
NC score	0.310013 (rank : 37)	θ value	0.000461057 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	31
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX8_HUMAN
NC score	0.309895 (rank : 38)	θ value	0.00175202 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX4_MOUSE
NC score	0.309889 (rank : 39)	θ value	0.00035302 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	64	Shared Neighborhood Hits	29
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX6_HUMAN
NC score	0.309868 (rank : 40)	θ value	0.000461057 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX8_MOUSE
NC score	0.306213 (rank : 41)	θ value	0.00175202 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CDYL2_HUMAN
NC score	0.233279 (rank : 42)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CDY1_HUMAN
NC score	0.222111 (rank : 43)	θ value	0.000786445 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
NC score	0.221594 (rank : 44)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDYL1_HUMAN
NC score	0.219226 (rank : 45)	θ value	0.00134147 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL_MOUSE
NC score	0.217622 (rank : 46)	θ value	0.00298849 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

MPP8_HUMAN
NC score	0.177657 (rank : 47)	θ value	3.77169e-06 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

SETD7_MOUSE
NC score	0.144683 (rank : 48)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
NC score	0.143442 (rank : 49)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

PHF11_HUMAN
NC score	0.097091 (rank : 50)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	69	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

SMYD3_MOUSE
NC score	0.087857 (rank : 51)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_HUMAN
NC score	0.087286 (rank : 52)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

RAI1_MOUSE
NC score	0.076757 (rank : 53)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	69	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF6_HUMAN
NC score	0.074879 (rank : 54)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	69	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
NC score	0.072702 (rank : 55)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF10_HUMAN
NC score	0.072175 (rank : 56)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	69	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

F107A_HUMAN
NC score	0.070840 (rank : 57)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O95990, Q96NH4	Gene names	FAM107A, DRR1, TU3A
Domain Architecture
Description	Protein FAM107A (Down-regulated in renal cell carcinoma 1) (Protein TU3A).

PHF10_MOUSE
NC score	0.070550 (rank : 58)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	69	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

TCF20_HUMAN
NC score	0.070149 (rank : 59)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	69	Target Neighborhood Hits	323	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

CHD1_HUMAN
NC score	0.069698 (rank : 60)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	337	Shared Neighborhood Hits	34
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.069587 (rank : 61)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RAI1_HUMAN
NC score	0.068999 (rank : 62)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	69	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CHD2_HUMAN
NC score	0.068973 (rank : 63)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	360	Shared Neighborhood Hits	37
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD3_HUMAN
NC score	0.067536 (rank : 64)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	69	Target Neighborhood Hits	397	Shared Neighborhood Hits	38
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
NC score	0.065554 (rank : 65)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	69	Target Neighborhood Hits	349	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TCF20_MOUSE
NC score	0.065247 (rank : 66)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	69	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PECI_HUMAN
NC score	0.064253 (rank : 67)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
NC score	0.063943 (rank : 68)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

DPF1_HUMAN
NC score	0.063894 (rank : 69)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	69	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

CHD4_HUMAN
NC score	0.063008 (rank : 70)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	69	Target Neighborhood Hits	365	Shared Neighborhood Hits	32
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.062578 (rank : 71)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	69	Target Neighborhood Hits	408	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

PHF7_HUMAN
NC score	0.062540 (rank : 72)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	69	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

ANR22_HUMAN
NC score	0.060654 (rank : 73)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	69	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

AIRE_HUMAN
NC score	0.058900 (rank : 74)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.058703 (rank : 75)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PHF7_MOUSE
NC score	0.057732 (rank : 76)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	69	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

DPF1_MOUSE
NC score	0.055989 (rank : 77)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	69	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.055568 (rank : 78)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	69	Target Neighborhood Hits	523	Shared Neighborhood Hits	8
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

K1333_MOUSE
NC score	0.055561 (rank : 79)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_HUMAN
NC score	0.055190 (rank : 80)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

REQU_MOUSE
NC score	0.055148 (rank : 81)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	69	Target Neighborhood Hits	519	Shared Neighborhood Hits	8
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

ANKY2_HUMAN
NC score	0.054520 (rank : 82)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	306	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

MYST4_HUMAN
NC score	0.054275 (rank : 83)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	69	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

RFXK_HUMAN
NC score	0.053923 (rank : 84)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANR49_MOUSE
NC score	0.053807 (rank : 85)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANKY2_MOUSE
NC score	0.053540 (rank : 86)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

INVS_MOUSE
NC score	0.052685 (rank : 87)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	69	Target Neighborhood Hits	609	Shared Neighborhood Hits	13
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANKR6_HUMAN
NC score	0.052356 (rank : 88)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

RFXK_MOUSE
NC score	0.052268 (rank : 89)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	69	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

PF21A_MOUSE
NC score	0.051761 (rank : 90)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	69	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.051613 (rank : 91)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	7
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

ANR49_HUMAN
NC score	0.051281 (rank : 92)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

CLPB_MOUSE
NC score	0.050813 (rank : 93)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	69	Target Neighborhood Hits	289	Shared Neighborhood Hits	4
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

NUD12_MOUSE
NC score	0.050415 (rank : 94)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	69	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

MYST4_MOUSE
NC score	0.050295 (rank : 95)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	69	Target Neighborhood Hits	416	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

CHD6_HUMAN
NC score	0.039492 (rank : 96)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_MOUSE
NC score	0.039052 (rank : 97)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	427	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD9_HUMAN
NC score	0.038705 (rank : 98)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

F107B_HUMAN
NC score	0.034843 (rank : 99)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H098	Gene names	FAM107B, C10orf45
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

CHD8_HUMAN
NC score	0.032087 (rank : 100)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

F107B_MOUSE
NC score	0.030589 (rank : 101)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TGF2	Gene names	Fam107b
Domain Architecture	No domain graphic available
Description	Protein FAM107B.

DNJC7_HUMAN
NC score	0.008928 (rank : 102)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	212	Shared Neighborhood Hits	4
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

DNJC7_MOUSE
NC score	0.007102 (rank : 103)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

SEP10_MOUSE
NC score	0.004896 (rank : 104)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C650, Q7TSA5	Gene names	Sept10
Domain Architecture	No domain graphic available
Description	Septin-10.

SEP10_HUMAN
NC score	0.004491 (rank : 105)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P0V9, Q9HAH6	Gene names	SEPT10
Domain Architecture	No domain graphic available
Description	Septin-10.

CROCC_MOUSE
NC score	0.000436 (rank : 106)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	1460	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

KCC1A_HUMAN
NC score	-0.004016 (rank : 107)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	846	Shared Neighborhood Hits	3
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_MOUSE
NC score	-0.004169 (rank : 108)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	845	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

ZN443_HUMAN
NC score	-0.004628 (rank : 109)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	759	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2A4	Gene names	ZNF443
Domain Architecture
Description	Zinc finger protein 443 (Krueppel-type zinc finger protein ZK1).