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Network neighborhood for query Sequence : K1333_HUMAN

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K1333_HUMAN
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K1333_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	0 (rank : 2)	NC score	0.990227 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF7_HUMAN
θ value	1.40689e-69 (rank : 3)	NC score	0.883734 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	6.98233e-69 (rank : 4)	NC score	0.891860 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF6_MOUSE
θ value	6.85773e-16 (rank : 5)	NC score	0.636086 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF6_HUMAN
θ value	8.95645e-16 (rank : 6)	NC score	0.638700 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF11_HUMAN
θ value	1.47974e-10 (rank : 7)	NC score	0.618959 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

HRX_HUMAN
θ value	2.36244e-08 (rank : 8)	NC score	0.304762 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
θ value	1.53129e-07 (rank : 9)	NC score	0.308422 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	722	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL3_HUMAN
θ value	1.99992e-07 (rank : 10)	NC score	0.236043 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	1644	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	4.45536e-07 (rank : 11)	NC score	0.248773 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
θ value	7.59969e-07 (rank : 12)	NC score	0.212976 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	1788	Shared Neighborhood Hits	32
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TCF20_HUMAN
θ value	9.92553e-07 (rank : 13)	NC score	0.337251 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	6.43352e-06 (rank : 14)	NC score	0.317584 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RAI1_HUMAN
θ value	1.43324e-05 (rank : 15)	NC score	0.328363 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	0.000121331 (rank : 16)	NC score	0.321988 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

NEDD4_HUMAN
θ value	0.00390308 (rank : 17)	NC score	0.062952 (rank : 51)
Query Neighborhood Hits	50	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

K0317_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.097689 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.097766 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

JADE1_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.157602 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	0.163984 (rank : 21)	NC score	0.157301 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	160	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

ZN662_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.003951 (rank : 81)
Query Neighborhood Hits	50	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZS27, Q6ZNF8, Q6ZQW8	Gene names	ZNF662
Domain Architecture	No domain graphic available
Description	Zinc finger protein 662.

HECD1_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.045949 (rank : 70)
Query Neighborhood Hits	50	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

BRD1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.104138 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

JADE2_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.131334 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MEGF9_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.016141 (rank : 74)
Query Neighborhood Hits	50	Target Neighborhood Hits	557	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

UBE3C_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.068962 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

UBE3C_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.064327 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

HECD2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.041531 (rank : 71)
Query Neighborhood Hits	50	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

ZN441_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.001002 (rank : 83)
Query Neighborhood Hits	50	Target Neighborhood Hits	754	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

JADE3_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.134273 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

TSP3_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.011034 (rank : 78)
Query Neighborhood Hits	50	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

ATRN_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.020086 (rank : 73)
Query Neighborhood Hits	50	Target Neighborhood Hits	519	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BRPF1_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.101536 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	259	Shared Neighborhood Hits	29
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

KCMA1_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.014834 (rank : 75)
Query Neighborhood Hits	50	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

RHPN2_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.014160 (rank : 76)
Query Neighborhood Hits	50	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

BRPF3_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.105680 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

JADE2_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.115292 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JHD3B_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.078553 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.074643 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	152	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

ZN599_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.000412 (rank : 84)
Query Neighborhood Hits	50	Target Neighborhood Hits	744	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NL3, Q569K0, Q5PRG1	Gene names	ZNF599
Domain Architecture	No domain graphic available
Description	Zinc finger protein 599.

ACAD8_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.007522 (rank : 80)
Query Neighborhood Hits	50	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKU7, Q9BUS8	Gene names	ACAD8, ARC42
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 8, mitochondrial precursor (EC 1.3.99.-) (ACAD-8) (Isobutyryl-CoA dehydrogenase) (Activator- recruited cofactor 42 kDa component) (ARC42).

JADE3_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.131983 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JHD3C_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.059753 (rank : 55)
Query Neighborhood Hits	50	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

RAD9B_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.013799 (rank : 77)
Query Neighborhood Hits	50	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WBX7	Gene names	Rad9b
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9B homolog (RAD9 homolog B) (mRAD9B).

TSP3_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.010557 (rank : 79)
Query Neighborhood Hits	50	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ATRN_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.020333 (rank : 72)
Query Neighborhood Hits	50	Target Neighborhood Hits	525	Shared Neighborhood Hits	10
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

MYST4_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.063946 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	671	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.065969 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

TRI55_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.003941 (rank : 82)
Query Neighborhood Hits	50	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

AF10_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.062633 (rank : 52)
Query Neighborhood Hits	50	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.062412 (rank : 53)
Query Neighborhood Hits	50	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF17_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.067394 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	230	Shared Neighborhood Hits	24
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

DPF1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.056257 (rank : 59)
Query Neighborhood Hits	50	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.053713 (rank : 65)
Query Neighborhood Hits	50	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EZH1_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.064635 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.064575 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.065162 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.064656 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

JHD3A_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.064464 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.064558 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.053836 (rank : 64)
Query Neighborhood Hits	50	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

MTF2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.050242 (rank : 69)
Query Neighborhood Hits	50	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MYST3_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.055514 (rank : 61)
Query Neighborhood Hits	50	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.054762 (rank : 63)
Query Neighborhood Hits	50	Target Neighborhood Hits	688	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.086660 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.089220 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	472	Shared Neighborhood Hits	26
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.056930 (rank : 58)
Query Neighborhood Hits	50	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.059953 (rank : 54)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PHF10_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.071000 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.070333 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF14_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.078154 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.079807 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	342	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

REQU_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.052808 (rank : 66)
Query Neighborhood Hits	50	Target Neighborhood Hits	523	Shared Neighborhood Hits	18
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.052168 (rank : 67)
Query Neighborhood Hits	50	Target Neighborhood Hits	519	Shared Neighborhood Hits	18
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SET1A_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.093135 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	690	Shared Neighborhood Hits	9
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETB2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.051857 (rank : 68)
Query Neighborhood Hits	50	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETD2_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.073285 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	412	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETD8_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.074389 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.070911 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SUV91_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.056133 (rank : 60)
Query Neighborhood Hits	50	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.055190 (rank : 62)
Query Neighborhood Hits	50	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.058424 (rank : 56)
Query Neighborhood Hits	50	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.056932 (rank : 57)
Query Neighborhood Hits	50	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

Hits sorted by NC score

K1333_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
NC score	0.990227 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF7_MOUSE
NC score	0.891860 (rank : 3)	θ value	6.98233e-69 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_HUMAN
NC score	0.883734 (rank : 4)	θ value	1.40689e-69 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF6_HUMAN
NC score	0.638700 (rank : 5)	θ value	8.95645e-16 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
NC score	0.636086 (rank : 6)	θ value	6.85773e-16 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF11_HUMAN
NC score	0.618959 (rank : 7)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TCF20_HUMAN
NC score	0.337251 (rank : 8)	θ value	9.92553e-07 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

RAI1_HUMAN
NC score	0.328363 (rank : 9)	θ value	1.43324e-05 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
NC score	0.321988 (rank : 10)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCF20_MOUSE
NC score	0.317584 (rank : 11)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MLL4_HUMAN
NC score	0.308422 (rank : 12)	θ value	1.53129e-07 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	722	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.304762 (rank : 13)	θ value	2.36244e-08 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL3_MOUSE
NC score	0.248773 (rank : 14)	θ value	4.45536e-07 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	1399	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.236043 (rank : 15)	θ value	1.99992e-07 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	1644	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL2_HUMAN
NC score	0.212976 (rank : 16)	θ value	7.59969e-07 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	1788	Shared Neighborhood Hits	32
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

JADE1_HUMAN
NC score	0.157602 (rank : 17)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	140	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.157301 (rank : 18)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	160	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_MOUSE
NC score	0.134273 (rank : 19)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	174	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_HUMAN
NC score	0.131983 (rank : 20)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	148	Shared Neighborhood Hits	30
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE2_HUMAN
NC score	0.131334 (rank : 21)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
NC score	0.115292 (rank : 22)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	560	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BRPF3_HUMAN
NC score	0.105680 (rank : 23)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

BRD1_HUMAN
NC score	0.104138 (rank : 24)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
NC score	0.101536 (rank : 25)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	259	Shared Neighborhood Hits	29
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

K0317_MOUSE
NC score	0.097766 (rank : 26)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHG5, Q6P9Q1, Q80YC4, Q8C5W5	Gene names	Kiaa0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

K0317_HUMAN
NC score	0.097689 (rank : 27)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

SET1A_HUMAN
NC score	0.093135 (rank : 28)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	50	Target Neighborhood Hits	690	Shared Neighborhood Hits	9
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NSD1_MOUSE
NC score	0.089220 (rank : 29)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	50	Target Neighborhood Hits	472	Shared Neighborhood Hits	26
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.086660 (rank : 30)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	50	Target Neighborhood Hits	427	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PHF14_MOUSE
NC score	0.079807 (rank : 31)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	50	Target Neighborhood Hits	342	Shared Neighborhood Hits	25
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JHD3B_HUMAN
NC score	0.078553 (rank : 32)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	128	Shared Neighborhood Hits	28
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

PHF14_HUMAN
NC score	0.078154 (rank : 33)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	50	Target Neighborhood Hits	447	Shared Neighborhood Hits	25
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

JHD3B_MOUSE
NC score	0.074643 (rank : 34)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	152	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

SETD8_HUMAN
NC score	0.074389 (rank : 35)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	50	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD2_HUMAN
NC score	0.073285 (rank : 36)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	50	Target Neighborhood Hits	412	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

PHF10_HUMAN
NC score	0.071000 (rank : 37)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	50	Target Neighborhood Hits	151	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

SETD8_MOUSE
NC score	0.070911 (rank : 38)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	50	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

PHF10_MOUSE
NC score	0.070333 (rank : 39)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	50	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

UBE3C_HUMAN
NC score	0.068962 (rank : 40)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

AF17_HUMAN
NC score	0.067394 (rank : 41)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	50	Target Neighborhood Hits	230	Shared Neighborhood Hits	24
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

MYST4_MOUSE
NC score	0.065969 (rank : 42)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	416	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

EZH2_HUMAN
NC score	0.065162 (rank : 43)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	50	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.064656 (rank : 44)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	50	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
NC score	0.064635 (rank : 45)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	50	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.064575 (rank : 46)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

JHD3A_MOUSE
NC score	0.064558 (rank : 47)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	50	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_HUMAN
NC score	0.064464 (rank : 48)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	50	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

UBE3C_MOUSE
NC score	0.064327 (rank : 49)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	48	Shared Neighborhood Hits	9
SwissProt Accessions	Q80U95, Q8BQZ6, Q8C7W6, Q8CDJ1, Q8VDL5	Gene names	Ube3c, Kiaa0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

MYST4_HUMAN
NC score	0.063946 (rank : 50)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	671	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NEDD4_HUMAN
NC score	0.062952 (rank : 51)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

AF10_HUMAN
NC score	0.062633 (rank : 52)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	50	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
NC score	0.062412 (rank : 53)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	50	Target Neighborhood Hits	182	Shared Neighborhood Hits	23
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

PF21A_MOUSE
NC score	0.059953 (rank : 54)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	50	Target Neighborhood Hits	285	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

JHD3C_MOUSE
NC score	0.059753 (rank : 55)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

SUV92_HUMAN
NC score	0.058424 (rank : 56)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	50	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.056932 (rank : 57)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	50	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

PF21A_HUMAN
NC score	0.056930 (rank : 58)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	50	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

DPF1_HUMAN
NC score	0.056257 (rank : 59)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	50	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

SUV91_HUMAN
NC score	0.056133 (rank : 60)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	50	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

MYST3_HUMAN
NC score	0.055514 (rank : 61)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	50	Target Neighborhood Hits	772	Shared Neighborhood Hits	21
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

SUV91_MOUSE
NC score	0.055190 (rank : 62)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	50	Target Neighborhood Hits	69	Shared Neighborhood Hits	5
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

MYST3_MOUSE
NC score	0.054762 (rank : 63)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	50	Target Neighborhood Hits	688	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

JHD3C_HUMAN
NC score	0.053836 (rank : 64)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	50	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

DPF1_MOUSE
NC score	0.053713 (rank : 65)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	50	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.052808 (rank : 66)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	50	Target Neighborhood Hits	523	Shared Neighborhood Hits	18
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.052168 (rank : 67)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	50	Target Neighborhood Hits	519	Shared Neighborhood Hits	18
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SETB2_HUMAN
NC score	0.051857 (rank : 68)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	50	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

MTF2_HUMAN
NC score	0.050242 (rank : 69)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	50	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

HECD1_HUMAN
NC score	0.045949 (rank : 70)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	371	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

HECD2_HUMAN
NC score	0.041531 (rank : 71)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5R9, Q5VZ97, Q5VZ99, Q8TCP5	Gene names	HECTD2
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase HECTD2 (HECT domain-containing protein 2).

ATRN_HUMAN
NC score	0.020333 (rank : 72)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	525	Shared Neighborhood Hits	10
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.020086 (rank : 73)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	519	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

MEGF9_HUMAN
NC score	0.016141 (rank : 74)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	557	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KCMA1_HUMAN
NC score	0.014834 (rank : 75)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

RHPN2_MOUSE
NC score	0.014160 (rank : 76)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BWR8, Q9DBN2	Gene names	Rhpn2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2).

RAD9B_MOUSE
NC score	0.013799 (rank : 77)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WBX7	Gene names	Rad9b
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint control protein RAD9B homolog (RAD9 homolog B) (mRAD9B).

TSP3_MOUSE
NC score	0.011034 (rank : 78)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_HUMAN
NC score	0.010557 (rank : 79)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ACAD8_HUMAN
NC score	0.007522 (rank : 80)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKU7, Q9BUS8	Gene names	ACAD8, ARC42
Domain Architecture
Description	Acyl-CoA dehydrogenase family member 8, mitochondrial precursor (EC 1.3.99.-) (ACAD-8) (Isobutyryl-CoA dehydrogenase) (Activator- recruited cofactor 42 kDa component) (ARC42).

ZN662_HUMAN
NC score	0.003951 (rank : 81)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZS27, Q6ZNF8, Q6ZQW8	Gene names	ZNF662
Domain Architecture	No domain graphic available
Description	Zinc finger protein 662.

TRI55_HUMAN
NC score	0.003941 (rank : 82)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

ZN441_HUMAN
NC score	0.001002 (rank : 83)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	754	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

ZN599_HUMAN
NC score	0.000412 (rank : 84)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	744	Shared Neighborhood Hits	4
SwissProt Accessions	Q96NL3, Q569K0, Q5PRG1	Gene names	ZNF599
Domain Architecture	No domain graphic available
Description	Zinc finger protein 599.