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Network neighborhood for query Sequence : NSD1_MOUSE

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NSD1_MOUSE
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NSD1_HUMAN
θ value	0 (rank : 1)	NC score	0.945555 (rank : 2)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	236
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	472	Target Neighborhood Hits	472	Shared Neighborhood Hits	472
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SETD2_HUMAN
θ value	2.18568e-46 (rank : 3)	NC score	0.641356 (rank : 3)
Query Neighborhood Hits	472	Target Neighborhood Hits	412	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SUV92_HUMAN
θ value	8.93572e-24 (rank : 4)	NC score	0.589334 (rank : 4)
Query Neighborhood Hits	472	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	2.20094e-22 (rank : 5)	NC score	0.581610 (rank : 5)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH2_HUMAN
θ value	2.06002e-20 (rank : 6)	NC score	0.565590 (rank : 8)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	4.58923e-20 (rank : 7)	NC score	0.563270 (rank : 9)
Query Neighborhood Hits	472	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
θ value	1.33526e-19 (rank : 8)	NC score	0.561693 (rank : 11)
Query Neighborhood Hits	472	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	1.33526e-19 (rank : 9)	NC score	0.562526 (rank : 10)
Query Neighborhood Hits	472	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SUV91_HUMAN
θ value	6.62687e-19 (rank : 10)	NC score	0.574718 (rank : 6)
Query Neighborhood Hits	472	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

HRX_HUMAN
θ value	1.47631e-18 (rank : 11)	NC score	0.552672 (rank : 12)
Query Neighborhood Hits	472	Target Neighborhood Hits	825	Shared Neighborhood Hits	191
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SUV91_MOUSE
θ value	1.47631e-18 (rank : 12)	NC score	0.567804 (rank : 7)
Query Neighborhood Hits	472	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

MLL4_HUMAN
θ value	3.07829e-16 (rank : 13)	NC score	0.542590 (rank : 13)
Query Neighborhood Hits	472	Target Neighborhood Hits	722	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EHMT1_HUMAN
θ value	4.02038e-16 (rank : 14)	NC score	0.282136 (rank : 47)
Query Neighborhood Hits	472	Target Neighborhood Hits	417	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SET1A_HUMAN
θ value	4.02038e-16 (rank : 15)	NC score	0.530480 (rank : 14)
Query Neighborhood Hits	472	Target Neighborhood Hits	690	Shared Neighborhood Hits	126
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EHMT2_HUMAN
θ value	5.25075e-16 (rank : 16)	NC score	0.287083 (rank : 45)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	6.85773e-16 (rank : 17)	NC score	0.293570 (rank : 42)
Query Neighborhood Hits	472	Target Neighborhood Hits	750	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MLL2_HUMAN
θ value	1.86753e-13 (rank : 18)	NC score	0.499758 (rank : 15)
Query Neighborhood Hits	472	Target Neighborhood Hits	1788	Shared Neighborhood Hits	255
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	9.26847e-13 (rank : 19)	NC score	0.473040 (rank : 17)
Query Neighborhood Hits	472	Target Neighborhood Hits	1644	Shared Neighborhood Hits	245
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	1.2105e-12 (rank : 20)	NC score	0.490926 (rank : 16)
Query Neighborhood Hits	472	Target Neighborhood Hits	1399	Shared Neighborhood Hits	237
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CHD5_HUMAN
θ value	4.59992e-12 (rank : 21)	NC score	0.279938 (rank : 49)
Query Neighborhood Hits	472	Target Neighborhood Hits	349	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD3_HUMAN
θ value	2.79066e-09 (rank : 22)	NC score	0.269678 (rank : 59)
Query Neighborhood Hits	472	Target Neighborhood Hits	397	Shared Neighborhood Hits	125
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	4.76016e-09 (rank : 23)	NC score	0.268891 (rank : 60)
Query Neighborhood Hits	472	Target Neighborhood Hits	365	Shared Neighborhood Hits	113
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	4.76016e-09 (rank : 24)	NC score	0.270364 (rank : 58)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

PHF12_HUMAN
θ value	4.76016e-09 (rank : 25)	NC score	0.407460 (rank : 25)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TIF1A_HUMAN
θ value	8.11959e-09 (rank : 26)	NC score	0.334283 (rank : 35)
Query Neighborhood Hits	472	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	1.06045e-08 (rank : 27)	NC score	0.340931 (rank : 34)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	107
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PHF12_MOUSE
θ value	1.80886e-08 (rank : 28)	NC score	0.403406 (rank : 26)
Query Neighborhood Hits	472	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TIF1G_HUMAN
θ value	1.80886e-08 (rank : 29)	NC score	0.316159 (rank : 37)
Query Neighborhood Hits	472	Target Neighborhood Hits	410	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	2.36244e-08 (rank : 30)	NC score	0.319911 (rank : 36)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

AIRE_HUMAN
θ value	3.08544e-08 (rank : 31)	NC score	0.449509 (rank : 20)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	88
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

SETB1_HUMAN
θ value	3.08544e-08 (rank : 32)	NC score	0.424029 (rank : 24)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	3.08544e-08 (rank : 33)	NC score	0.427981 (rank : 23)
Query Neighborhood Hits	472	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

AIRE_MOUSE
θ value	4.0297e-08 (rank : 34)	NC score	0.441962 (rank : 21)
Query Neighborhood Hits	472	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PKCB1_HUMAN
θ value	2.61198e-07 (rank : 35)	NC score	0.372804 (rank : 29)
Query Neighborhood Hits	472	Target Neighborhood Hits	488	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRI66_HUMAN
θ value	5.81887e-07 (rank : 36)	NC score	0.342943 (rank : 33)
Query Neighborhood Hits	472	Target Neighborhood Hits	479	Shared Neighborhood Hits	114
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SETD8_HUMAN
θ value	9.92553e-07 (rank : 37)	NC score	0.465416 (rank : 19)
Query Neighborhood Hits	472	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	1.29631e-06 (rank : 38)	NC score	0.466594 (rank : 18)
Query Neighborhood Hits	472	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

TRI66_MOUSE
θ value	1.29631e-06 (rank : 39)	NC score	0.345014 (rank : 32)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	116
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PP1RA_HUMAN
θ value	2.21117e-06 (rank : 40)	NC score	0.136149 (rank : 117)
Query Neighborhood Hits	472	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

BPTF_HUMAN
θ value	2.88788e-06 (rank : 41)	NC score	0.312493 (rank : 38)
Query Neighborhood Hits	472	Target Neighborhood Hits	786	Shared Neighborhood Hits	158
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SETB2_HUMAN
θ value	1.43324e-05 (rank : 42)	NC score	0.434321 (rank : 22)
Query Neighborhood Hits	472	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

MYST4_HUMAN
θ value	2.44474e-05 (rank : 43)	NC score	0.279435 (rank : 51)
Query Neighborhood Hits	472	Target Neighborhood Hits	671	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PF21A_MOUSE
θ value	2.44474e-05 (rank : 44)	NC score	0.387518 (rank : 27)
Query Neighborhood Hits	472	Target Neighborhood Hits	285	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

MYST4_MOUSE
θ value	4.1701e-05 (rank : 45)	NC score	0.276910 (rank : 54)
Query Neighborhood Hits	472	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NACAM_MOUSE
θ value	5.44631e-05 (rank : 46)	NC score	0.166950 (rank : 106)
Query Neighborhood Hits	472	Target Neighborhood Hits	1866	Shared Neighborhood Hits	213
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PF21B_HUMAN
θ value	5.44631e-05 (rank : 47)	NC score	0.363952 (rank : 30)
Query Neighborhood Hits	472	Target Neighborhood Hits	197	Shared Neighborhood Hits	91
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST3_MOUSE
θ value	7.1131e-05 (rank : 48)	NC score	0.277740 (rank : 53)
Query Neighborhood Hits	472	Target Neighborhood Hits	688	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PCSK5_MOUSE
θ value	7.1131e-05 (rank : 49)	NC score	0.056552 (rank : 383)
Query Neighborhood Hits	472	Target Neighborhood Hits	613	Shared Neighborhood Hits	33
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PF21A_HUMAN
θ value	7.1131e-05 (rank : 50)	NC score	0.384196 (rank : 28)
Query Neighborhood Hits	472	Target Neighborhood Hits	303	Shared Neighborhood Hits	109
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

TIF1B_HUMAN
θ value	7.1131e-05 (rank : 51)	NC score	0.283706 (rank : 46)
Query Neighborhood Hits	472	Target Neighborhood Hits	312	Shared Neighborhood Hits	77
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

MYST3_HUMAN
θ value	9.29e-05 (rank : 52)	NC score	0.274782 (rank : 55)
Query Neighborhood Hits	472	Target Neighborhood Hits	772	Shared Neighborhood Hits	165
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PP1RA_MOUSE
θ value	0.000121331 (rank : 53)	NC score	0.125896 (rank : 129)
Query Neighborhood Hits	472	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

LY10_HUMAN
θ value	0.000158464 (rank : 54)	NC score	0.302665 (rank : 39)
Query Neighborhood Hits	472	Target Neighborhood Hits	151	Shared Neighborhood Hits	73
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

ZAN_HUMAN
θ value	0.000158464 (rank : 55)	NC score	0.094833 (rank : 193)
Query Neighborhood Hits	472	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

DSPP_HUMAN
θ value	0.00020696 (rank : 56)	NC score	0.119005 (rank : 143)
Query Neighborhood Hits	472	Target Neighborhood Hits	645	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SP110_HUMAN
θ value	0.000270298 (rank : 57)	NC score	0.291635 (rank : 43)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

ING2_HUMAN
θ value	0.00035302 (rank : 58)	NC score	0.216087 (rank : 88)
Query Neighborhood Hits	472	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

PF21B_MOUSE
θ value	0.000461057 (rank : 59)	NC score	0.351869 (rank : 31)
Query Neighborhood Hits	472	Target Neighborhood Hits	278	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF7_HUMAN
θ value	0.000461057 (rank : 60)	NC score	0.189314 (rank : 102)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

TIF1B_MOUSE
θ value	0.000602161 (rank : 61)	NC score	0.280900 (rank : 48)
Query Neighborhood Hits	472	Target Neighborhood Hits	276	Shared Neighborhood Hits	76
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ING2_MOUSE
θ value	0.000786445 (rank : 62)	NC score	0.215852 (rank : 89)
Query Neighborhood Hits	472	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

RUSC1_HUMAN
θ value	0.000786445 (rank : 63)	NC score	0.063576 (rank : 328)
Query Neighborhood Hits	472	Target Neighborhood Hits	226	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

ING3_HUMAN
θ value	0.00102713 (rank : 64)	NC score	0.212913 (rank : 90)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
θ value	0.00102713 (rank : 65)	NC score	0.210910 (rank : 91)
Query Neighborhood Hits	472	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

JADE3_MOUSE
θ value	0.00102713 (rank : 66)	NC score	0.243641 (rank : 70)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

NFH_HUMAN
θ value	0.00102713 (rank : 67)	NC score	0.072550 (rank : 281)
Query Neighborhood Hits	472	Target Neighborhood Hits	1242	Shared Neighborhood Hits	133
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ING5_HUMAN
θ value	0.00134147 (rank : 68)	NC score	0.230089 (rank : 81)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	0.00134147 (rank : 69)	NC score	0.227283 (rank : 82)
Query Neighborhood Hits	472	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

JAD1A_HUMAN
θ value	0.00134147 (rank : 70)	NC score	0.240027 (rank : 77)
Query Neighborhood Hits	472	Target Neighborhood Hits	328	Shared Neighborhood Hits	99
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JADE1_HUMAN
θ value	0.00134147 (rank : 71)	NC score	0.242257 (rank : 72)
Query Neighborhood Hits	472	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	0.00134147 (rank : 72)	NC score	0.241606 (rank : 74)
Query Neighborhood Hits	472	Target Neighborhood Hits	160	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
θ value	0.00134147 (rank : 73)	NC score	0.241278 (rank : 75)
Query Neighborhood Hits	472	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

BRPF1_HUMAN
θ value	0.00175202 (rank : 74)	NC score	0.255825 (rank : 66)
Query Neighborhood Hits	472	Target Neighborhood Hits	259	Shared Neighborhood Hits	109
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JAD1C_HUMAN
θ value	0.00175202 (rank : 75)	NC score	0.223211 (rank : 85)
Query Neighborhood Hits	472	Target Neighborhood Hits	187	Shared Neighborhood Hits	83
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.00175202 (rank : 76)	NC score	0.223780 (rank : 83)
Query Neighborhood Hits	472	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

BRD1_HUMAN
θ value	0.00228821 (rank : 77)	NC score	0.242510 (rank : 71)
Query Neighborhood Hits	472	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

JADE2_MOUSE
θ value	0.00228821 (rank : 78)	NC score	0.246160 (rank : 68)
Query Neighborhood Hits	472	Target Neighborhood Hits	560	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1802_MOUSE
θ value	0.00228821 (rank : 79)	NC score	0.109077 (rank : 162)
Query Neighborhood Hits	472	Target Neighborhood Hits	1596	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

AF10_HUMAN
θ value	0.00298849 (rank : 80)	NC score	0.191302 (rank : 101)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	0.00298849 (rank : 81)	NC score	0.193145 (rank : 99)
Query Neighborhood Hits	472	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

ATRX_MOUSE
θ value	0.00298849 (rank : 82)	NC score	0.151857 (rank : 107)
Query Neighborhood Hits	472	Target Neighborhood Hits	682	Shared Neighborhood Hits	101
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ING1_HUMAN
θ value	0.00298849 (rank : 83)	NC score	0.202471 (rank : 95)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	0.00298849 (rank : 84)	NC score	0.202329 (rank : 96)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

TXND2_HUMAN
θ value	0.00298849 (rank : 85)	NC score	0.151583 (rank : 108)
Query Neighborhood Hits	472	Target Neighborhood Hits	793	Shared Neighborhood Hits	148
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AN30A_HUMAN
θ value	0.00390308 (rank : 86)	NC score	0.061294 (rank : 344)
Query Neighborhood Hits	472	Target Neighborhood Hits	1119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ATRX_HUMAN
θ value	0.00390308 (rank : 87)	NC score	0.143185 (rank : 112)
Query Neighborhood Hits	472	Target Neighborhood Hits	842	Shared Neighborhood Hits	116
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

JADE2_HUMAN
θ value	0.00390308 (rank : 88)	NC score	0.244301 (rank : 69)
Query Neighborhood Hits	472	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

SRRM1_HUMAN
θ value	0.00390308 (rank : 89)	NC score	0.170604 (rank : 104)
Query Neighborhood Hits	472	Target Neighborhood Hits	690	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ZMY11_MOUSE
θ value	0.00509761 (rank : 90)	NC score	0.252918 (rank : 67)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

BAZ1B_HUMAN
θ value	0.00869519 (rank : 91)	NC score	0.268410 (rank : 62)
Query Neighborhood Hits	472	Target Neighborhood Hits	701	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	0.00869519 (rank : 92)	NC score	0.279809 (rank : 50)
Query Neighborhood Hits	472	Target Neighborhood Hits	394	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRPF3_HUMAN
θ value	0.00869519 (rank : 93)	NC score	0.240959 (rank : 76)
Query Neighborhood Hits	472	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

AF17_HUMAN
θ value	0.0113563 (rank : 94)	NC score	0.206226 (rank : 93)
Query Neighborhood Hits	472	Target Neighborhood Hits	230	Shared Neighborhood Hits	96
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

NCOA6_HUMAN
θ value	0.0113563 (rank : 95)	NC score	0.130724 (rank : 122)
Query Neighborhood Hits	472	Target Neighborhood Hits	1202	Shared Neighborhood Hits	150
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BAZ2A_HUMAN
θ value	0.0148317 (rank : 96)	NC score	0.272607 (rank : 56)
Query Neighborhood Hits	472	Target Neighborhood Hits	780	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

ELOA1_HUMAN
θ value	0.0148317 (rank : 97)	NC score	0.122611 (rank : 136)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

ING4_HUMAN
θ value	0.0148317 (rank : 98)	NC score	0.197066 (rank : 97)
Query Neighborhood Hits	472	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	0.0148317 (rank : 99)	NC score	0.196004 (rank : 98)
Query Neighborhood Hits	472	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

MAP1B_HUMAN
θ value	0.0193708 (rank : 100)	NC score	0.105200 (rank : 170)
Query Neighborhood Hits	472	Target Neighborhood Hits	903	Shared Neighborhood Hits	118
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFH_MOUSE
θ value	0.0193708 (rank : 101)	NC score	0.114649 (rank : 152)
Query Neighborhood Hits	472	Target Neighborhood Hits	2247	Shared Neighborhood Hits	256
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RSF1_HUMAN
θ value	0.0193708 (rank : 102)	NC score	0.295607 (rank : 40)
Query Neighborhood Hits	472	Target Neighborhood Hits	539	Shared Neighborhood Hits	127
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SRRM1_MOUSE
θ value	0.0193708 (rank : 103)	NC score	0.171136 (rank : 103)
Query Neighborhood Hits	472	Target Neighborhood Hits	966	Shared Neighborhood Hits	159
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	0.0193708 (rank : 104)	NC score	0.133110 (rank : 120)
Query Neighborhood Hits	472	Target Neighborhood Hits	1470	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CD2L5_HUMAN
θ value	0.0252991 (rank : 105)	NC score	0.013007 (rank : 617)
Query Neighborhood Hits	472	Target Neighborhood Hits	987	Shared Neighborhood Hits	45
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

GON4L_MOUSE
θ value	0.0252991 (rank : 106)	NC score	0.089744 (rank : 204)
Query Neighborhood Hits	472	Target Neighborhood Hits	455	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

PHF7_MOUSE
θ value	0.0252991 (rank : 107)	NC score	0.169005 (rank : 105)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

DPF1_HUMAN
θ value	0.0330416 (rank : 108)	NC score	0.279068 (rank : 52)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

JAD1D_HUMAN
θ value	0.0330416 (rank : 109)	NC score	0.223564 (rank : 84)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MAGE1_HUMAN
θ value	0.0330416 (rank : 110)	NC score	0.084116 (rank : 224)
Query Neighborhood Hits	472	Target Neighborhood Hits	1389	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RGS3_MOUSE
θ value	0.0330416 (rank : 111)	NC score	0.107783 (rank : 165)
Query Neighborhood Hits	472	Target Neighborhood Hits	1621	Shared Neighborhood Hits	189
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TRDN_HUMAN
θ value	0.0330416 (rank : 112)	NC score	0.091480 (rank : 198)
Query Neighborhood Hits	472	Target Neighborhood Hits	542	Shared Neighborhood Hits	60
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BAZ1A_HUMAN
θ value	0.0431538 (rank : 113)	NC score	0.270406 (rank : 57)
Query Neighborhood Hits	472	Target Neighborhood Hits	693	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ2A_MOUSE
θ value	0.0431538 (rank : 114)	NC score	0.268808 (rank : 61)
Query Neighborhood Hits	472	Target Neighborhood Hits	744	Shared Neighborhood Hits	161
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

COFA1_HUMAN
θ value	0.0431538 (rank : 115)	NC score	0.038313 (rank : 498)
Query Neighborhood Hits	472	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

HUWE1_MOUSE
θ value	0.0431538 (rank : 116)	NC score	0.036864 (rank : 502)
Query Neighborhood Hits	472	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

SON_HUMAN
θ value	0.0431538 (rank : 117)	NC score	0.130725 (rank : 121)
Query Neighborhood Hits	472	Target Neighborhood Hits	1568	Shared Neighborhood Hits	186
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

AAK1_HUMAN
θ value	0.0563607 (rank : 118)	NC score	0.031053 (rank : 523)
Query Neighborhood Hits	472	Target Neighborhood Hits	1077	Shared Neighborhood Hits	87
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

BCL3_MOUSE
θ value	0.0563607 (rank : 119)	NC score	0.047054 (rank : 466)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CD2L5_MOUSE
θ value	0.0563607 (rank : 120)	NC score	0.014390 (rank : 602)
Query Neighborhood Hits	472	Target Neighborhood Hits	1011	Shared Neighborhood Hits	59
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

MK07_MOUSE
θ value	0.0563607 (rank : 121)	NC score	0.018338 (rank : 577)
Query Neighborhood Hits	472	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

SRRM2_HUMAN
θ value	0.0563607 (rank : 122)	NC score	0.139189 (rank : 114)
Query Neighborhood Hits	472	Target Neighborhood Hits	1296	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TARA_HUMAN
θ value	0.0563607 (rank : 123)	NC score	0.120916 (rank : 139)
Query Neighborhood Hits	472	Target Neighborhood Hits	1626	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

WNK2_HUMAN
θ value	0.0563607 (rank : 124)	NC score	0.029363 (rank : 531)
Query Neighborhood Hits	472	Target Neighborhood Hits	1407	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZMY11_HUMAN
θ value	0.0563607 (rank : 125)	NC score	0.237537 (rank : 78)
Query Neighborhood Hits	472	Target Neighborhood Hits	201	Shared Neighborhood Hits	81
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

BAZ2B_HUMAN
θ value	0.0736092 (rank : 126)	NC score	0.242072 (rank : 73)
Query Neighborhood Hits	472	Target Neighborhood Hits	803	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

JHD3C_HUMAN
θ value	0.0736092 (rank : 127)	NC score	0.122656 (rank : 135)
Query Neighborhood Hits	472	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

PCLO_MOUSE
θ value	0.0736092 (rank : 128)	NC score	0.111204 (rank : 157)
Query Neighborhood Hits	472	Target Neighborhood Hits	2275	Shared Neighborhood Hits	221
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

REQU_HUMAN
θ value	0.0736092 (rank : 129)	NC score	0.258035 (rank : 64)
Query Neighborhood Hits	472	Target Neighborhood Hits	523	Shared Neighborhood Hits	84
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	0.0736092 (rank : 130)	NC score	0.256181 (rank : 65)
Query Neighborhood Hits	472	Target Neighborhood Hits	519	Shared Neighborhood Hits	82
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

UHRF1_MOUSE
θ value	0.0736092 (rank : 131)	NC score	0.219894 (rank : 86)
Query Neighborhood Hits	472	Target Neighborhood Hits	278	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

DPF1_MOUSE
θ value	0.0961366 (rank : 132)	NC score	0.258195 (rank : 63)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

UHRF2_HUMAN
θ value	0.0961366 (rank : 133)	NC score	0.203290 (rank : 94)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	75
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

HTSF1_HUMAN
θ value	0.125558 (rank : 134)	NC score	0.054667 (rank : 405)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

K0329_HUMAN
θ value	0.125558 (rank : 135)	NC score	0.047194 (rank : 464)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

PCLO_HUMAN
θ value	0.125558 (rank : 136)	NC score	0.126267 (rank : 128)
Query Neighborhood Hits	472	Target Neighborhood Hits	2046	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHF10_HUMAN
θ value	0.125558 (rank : 137)	NC score	0.295306 (rank : 41)
Query Neighborhood Hits	472	Target Neighborhood Hits	151	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

ZN750_MOUSE
θ value	0.125558 (rank : 138)	NC score	0.084972 (rank : 219)
Query Neighborhood Hits	472	Target Neighborhood Hits	346	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

AFF2_MOUSE
θ value	0.163984 (rank : 139)	NC score	0.075561 (rank : 262)
Query Neighborhood Hits	472	Target Neighborhood Hits	225	Shared Neighborhood Hits	58
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CBP_MOUSE
θ value	0.163984 (rank : 140)	NC score	0.125215 (rank : 131)
Query Neighborhood Hits	472	Target Neighborhood Hits	1051	Shared Neighborhood Hits	157
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CYLC2_HUMAN
θ value	0.163984 (rank : 141)	NC score	0.081044 (rank : 235)
Query Neighborhood Hits	472	Target Neighborhood Hits	223	Shared Neighborhood Hits	41
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DDEF1_MOUSE
θ value	0.163984 (rank : 142)	NC score	0.042506 (rank : 477)
Query Neighborhood Hits	472	Target Neighborhood Hits	592	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DSPP_MOUSE
θ value	0.163984 (rank : 143)	NC score	0.089862 (rank : 203)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	59
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FGD1_MOUSE
θ value	0.163984 (rank : 144)	NC score	0.039045 (rank : 494)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	52
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

LCP2_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.095439 (rank : 190)
Query Neighborhood Hits	472	Target Neighborhood Hits	531	Shared Neighborhood Hits	84
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MARK4_MOUSE
θ value	0.163984 (rank : 146)	NC score	0.004469 (rank : 664)
Query Neighborhood Hits	472	Target Neighborhood Hits	898	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MAST1_MOUSE
θ value	0.163984 (rank : 147)	NC score	0.006000 (rank : 658)
Query Neighborhood Hits	472	Target Neighborhood Hits	1123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

RASF7_HUMAN
θ value	0.163984 (rank : 148)	NC score	0.041124 (rank : 481)
Query Neighborhood Hits	472	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

SNAI_HUMAN
θ value	0.163984 (rank : 149)	NC score	0.001471 (rank : 668)
Query Neighborhood Hits	472	Target Neighborhood Hits	708	Shared Neighborhood Hits	19
SwissProt Accessions	O95863, Q9P113, Q9UBP7, Q9UHH7	Gene names	SNAI1, SNAH
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

TIM44_MOUSE
θ value	0.163984 (rank : 150)	NC score	0.051678 (rank : 428)
Query Neighborhood Hits	472	Target Neighborhood Hits	235	Shared Neighborhood Hits	22
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

GTSE1_HUMAN
θ value	0.21417 (rank : 151)	NC score	0.088118 (rank : 209)
Query Neighborhood Hits	472	Target Neighborhood Hits	193	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HDGR3_HUMAN
θ value	0.21417 (rank : 152)	NC score	0.096717 (rank : 186)
Query Neighborhood Hits	472	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

HDGR3_MOUSE
θ value	0.21417 (rank : 153)	NC score	0.096996 (rank : 184)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

MAP1A_HUMAN
θ value	0.21417 (rank : 154)	NC score	0.102990 (rank : 174)
Query Neighborhood Hits	472	Target Neighborhood Hits	1626	Shared Neighborhood Hits	172
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PPIG_HUMAN
θ value	0.21417 (rank : 155)	NC score	0.041965 (rank : 480)
Query Neighborhood Hits	472	Target Neighborhood Hits	670	Shared Neighborhood Hits	85
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CIR_MOUSE
θ value	0.279714 (rank : 156)	NC score	0.073634 (rank : 276)
Query Neighborhood Hits	472	Target Neighborhood Hits	255	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

IASPP_MOUSE
θ value	0.279714 (rank : 157)	NC score	0.062861 (rank : 331)
Query Neighborhood Hits	472	Target Neighborhood Hits	1024	Shared Neighborhood Hits	103
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

JHD1B_HUMAN
θ value	0.279714 (rank : 158)	NC score	0.058421 (rank : 371)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

MINK1_HUMAN
θ value	0.279714 (rank : 159)	NC score	0.012879 (rank : 618)
Query Neighborhood Hits	472	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MUC5B_HUMAN
θ value	0.279714 (rank : 160)	NC score	0.069042 (rank : 297)
Query Neighborhood Hits	472	Target Neighborhood Hits	1020	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYCB2_MOUSE
θ value	0.279714 (rank : 161)	NC score	0.051436 (rank : 429)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NPBL_MOUSE
θ value	0.279714 (rank : 162)	NC score	0.127978 (rank : 126)
Query Neighborhood Hits	472	Target Neighborhood Hits	1041	Shared Neighborhood Hits	150
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PHF10_MOUSE
θ value	0.279714 (rank : 163)	NC score	0.288271 (rank : 44)
Query Neighborhood Hits	472	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

RIMB1_MOUSE
θ value	0.279714 (rank : 164)	NC score	0.043761 (rank : 474)
Query Neighborhood Hits	472	Target Neighborhood Hits	1376	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SON_MOUSE
θ value	0.279714 (rank : 165)	NC score	0.113249 (rank : 155)
Query Neighborhood Hits	472	Target Neighborhood Hits	957	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPTN5_HUMAN
θ value	0.279714 (rank : 166)	NC score	0.014357 (rank : 603)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

ZN507_HUMAN
θ value	0.279714 (rank : 167)	NC score	0.002468 (rank : 667)
Query Neighborhood Hits	472	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

ANK2_HUMAN
θ value	0.365318 (rank : 168)	NC score	0.083342 (rank : 227)
Query Neighborhood Hits	472	Target Neighborhood Hits	1615	Shared Neighborhood Hits	202
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BRAP_HUMAN
θ value	0.365318 (rank : 169)	NC score	0.047103 (rank : 465)
Query Neighborhood Hits	472	Target Neighborhood Hits	560	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	0.365318 (rank : 170)	NC score	0.050191 (rank : 447)
Query Neighborhood Hits	472	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

FOG2_MOUSE
θ value	0.365318 (rank : 171)	NC score	0.012534 (rank : 621)
Query Neighborhood Hits	472	Target Neighborhood Hits	714	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

FRAS1_HUMAN
θ value	0.365318 (rank : 172)	NC score	0.036490 (rank : 505)
Query Neighborhood Hits	472	Target Neighborhood Hits	759	Shared Neighborhood Hits	38
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HDGF_HUMAN
θ value	0.365318 (rank : 173)	NC score	0.096213 (rank : 188)
Query Neighborhood Hits	472	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

HDGF_MOUSE
θ value	0.365318 (rank : 174)	NC score	0.099473 (rank : 177)
Query Neighborhood Hits	472	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

LAD1_HUMAN
θ value	0.365318 (rank : 175)	NC score	0.137289 (rank : 115)
Query Neighborhood Hits	472	Target Neighborhood Hits	441	Shared Neighborhood Hits	93
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

NCOA6_MOUSE
θ value	0.365318 (rank : 176)	NC score	0.117828 (rank : 145)
Query Neighborhood Hits	472	Target Neighborhood Hits	1076	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NIPBL_HUMAN
θ value	0.365318 (rank : 177)	NC score	0.129515 (rank : 123)
Query Neighborhood Hits	472	Target Neighborhood Hits	1311	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHF20_MOUSE
θ value	0.365318 (rank : 178)	NC score	0.110814 (rank : 159)
Query Neighborhood Hits	472	Target Neighborhood Hits	513	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PSIP1_HUMAN
θ value	0.365318 (rank : 179)	NC score	0.099244 (rank : 178)
Query Neighborhood Hits	472	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
θ value	0.365318 (rank : 180)	NC score	0.099157 (rank : 179)
Query Neighborhood Hits	472	Target Neighborhood Hits	313	Shared Neighborhood Hits	52
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

SEM6C_HUMAN
θ value	0.365318 (rank : 181)	NC score	0.011534 (rank : 629)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

TIM44_HUMAN
θ value	0.365318 (rank : 182)	NC score	0.047791 (rank : 460)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

TULP1_MOUSE
θ value	0.365318 (rank : 183)	NC score	0.032664 (rank : 514)
Query Neighborhood Hits	472	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

UHRF1_HUMAN
θ value	0.365318 (rank : 184)	NC score	0.216509 (rank : 87)
Query Neighborhood Hits	472	Target Neighborhood Hits	272	Shared Neighborhood Hits	75
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ZN746_HUMAN
θ value	0.365318 (rank : 185)	NC score	0.001238 (rank : 669)
Query Neighborhood Hits	472	Target Neighborhood Hits	745	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

AB1IP_MOUSE
θ value	0.47712 (rank : 186)	NC score	0.046215 (rank : 468)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ATN1_HUMAN
θ value	0.47712 (rank : 187)	NC score	0.087871 (rank : 210)
Query Neighborhood Hits	472	Target Neighborhood Hits	676	Shared Neighborhood Hits	96
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL3_HUMAN
θ value	0.47712 (rank : 188)	NC score	0.040853 (rank : 483)
Query Neighborhood Hits	472	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

JAD1D_MOUSE
θ value	0.47712 (rank : 189)	NC score	0.208108 (rank : 92)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

MINT_HUMAN
θ value	0.47712 (rank : 190)	NC score	0.087237 (rank : 211)
Query Neighborhood Hits	472	Target Neighborhood Hits	1291	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PDZD2_HUMAN
θ value	0.47712 (rank : 191)	NC score	0.071576 (rank : 283)
Query Neighborhood Hits	472	Target Neighborhood Hits	772	Shared Neighborhood Hits	96
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PWWP2_HUMAN
θ value	0.47712 (rank : 192)	NC score	0.104737 (rank : 171)
Query Neighborhood Hits	472	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

SNPC2_MOUSE
θ value	0.47712 (rank : 193)	NC score	0.046080 (rank : 469)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

TCF20_MOUSE
θ value	0.47712 (rank : 194)	NC score	0.135596 (rank : 118)
Query Neighborhood Hits	472	Target Neighborhood Hits	396	Shared Neighborhood Hits	91
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

CS016_HUMAN
θ value	0.62314 (rank : 195)	NC score	0.110455 (rank : 161)
Query Neighborhood Hits	472	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

DNMT1_MOUSE
θ value	0.62314 (rank : 196)	NC score	0.055740 (rank : 394)
Query Neighborhood Hits	472	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

FOG1_HUMAN
θ value	0.62314 (rank : 197)	NC score	0.021678 (rank : 561)
Query Neighborhood Hits	472	Target Neighborhood Hits	981	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GASP2_MOUSE
θ value	0.62314 (rank : 198)	NC score	0.044408 (rank : 472)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

K1802_HUMAN
θ value	0.62314 (rank : 199)	NC score	0.085489 (rank : 217)
Query Neighborhood Hits	472	Target Neighborhood Hits	1378	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NOTC1_MOUSE
θ value	0.62314 (rank : 200)	NC score	0.022236 (rank : 559)
Query Neighborhood Hits	472	Target Neighborhood Hits	916	Shared Neighborhood Hits	42
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

WBP4_MOUSE
θ value	0.62314 (rank : 201)	NC score	0.060220 (rank : 352)
Query Neighborhood Hits	472	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

AL2S4_MOUSE
θ value	0.813845 (rank : 202)	NC score	0.073293 (rank : 278)
Query Neighborhood Hits	472	Target Neighborhood Hits	193	Shared Neighborhood Hits	45
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

IRS2_HUMAN
θ value	0.813845 (rank : 203)	NC score	0.047386 (rank : 462)
Query Neighborhood Hits	472	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

JHD1B_MOUSE
θ value	0.813845 (rank : 204)	NC score	0.056225 (rank : 386)
Query Neighborhood Hits	472	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

LMD1_HUMAN
θ value	0.813845 (rank : 205)	NC score	0.036778 (rank : 504)
Query Neighborhood Hits	472	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MARK4_HUMAN
θ value	0.813845 (rank : 206)	NC score	0.003446 (rank : 665)
Query Neighborhood Hits	472	Target Neighborhood Hits	886	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

NFRKB_MOUSE
θ value	0.813845 (rank : 207)	NC score	0.070758 (rank : 289)
Query Neighborhood Hits	472	Target Neighborhood Hits	393	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

OBSCN_HUMAN
θ value	0.813845 (rank : 208)	NC score	0.008685 (rank : 649)
Query Neighborhood Hits	472	Target Neighborhood Hits	1931	Shared Neighborhood Hits	102
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OSBL3_HUMAN
θ value	0.813845 (rank : 209)	NC score	0.013654 (rank : 612)
Query Neighborhood Hits	472	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PTPRB_HUMAN
θ value	0.813845 (rank : 210)	NC score	0.006195 (rank : 657)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

RAI1_MOUSE
θ value	0.813845 (rank : 211)	NC score	0.147537 (rank : 110)
Query Neighborhood Hits	472	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SEL1L_MOUSE
θ value	0.813845 (rank : 212)	NC score	0.022767 (rank : 556)
Query Neighborhood Hits	472	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SRGP1_HUMAN
θ value	0.813845 (rank : 213)	NC score	0.017170 (rank : 585)
Query Neighborhood Hits	472	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SYN1_MOUSE
θ value	0.813845 (rank : 214)	NC score	0.076359 (rank : 258)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	67
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TATD2_HUMAN
θ value	0.813845 (rank : 215)	NC score	0.049245 (rank : 453)
Query Neighborhood Hits	472	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

TTF2_MOUSE
θ value	0.813845 (rank : 216)	NC score	0.076069 (rank : 260)
Query Neighborhood Hits	472	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

VPS41_HUMAN
θ value	0.813845 (rank : 217)	NC score	0.040381 (rank : 485)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

WNK1_HUMAN
θ value	0.813845 (rank : 218)	NC score	0.015458 (rank : 595)
Query Neighborhood Hits	472	Target Neighborhood Hits	1158	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

BNC1_MOUSE
θ value	1.06291 (rank : 219)	NC score	0.018291 (rank : 580)
Query Neighborhood Hits	472	Target Neighborhood Hits	582	Shared Neighborhood Hits	18
SwissProt Accessions	O35914, O54886	Gene names	Bnc1, Bnc
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

COFA1_MOUSE
θ value	1.06291 (rank : 220)	NC score	0.029338 (rank : 533)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

ICAL_HUMAN
θ value	1.06291 (rank : 221)	NC score	0.070623 (rank : 290)
Query Neighborhood Hits	472	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

ITIH3_MOUSE
θ value	1.06291 (rank : 222)	NC score	0.022528 (rank : 557)
Query Neighborhood Hits	472	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

MYO15_HUMAN
θ value	1.06291 (rank : 223)	NC score	0.030022 (rank : 528)
Query Neighborhood Hits	472	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RPA1_HUMAN
θ value	1.06291 (rank : 224)	NC score	0.017841 (rank : 583)
Query Neighborhood Hits	472	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SAFB2_MOUSE
θ value	1.06291 (rank : 225)	NC score	0.025778 (rank : 542)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

SMYD5_HUMAN
θ value	1.06291 (rank : 226)	NC score	0.037405 (rank : 501)
Query Neighborhood Hits	472	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

SYP2L_HUMAN
θ value	1.06291 (rank : 227)	NC score	0.038975 (rank : 495)
Query Neighborhood Hits	472	Target Neighborhood Hits	400	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TAU_HUMAN
θ value	1.06291 (rank : 228)	NC score	0.060015 (rank : 356)
Query Neighborhood Hits	472	Target Neighborhood Hits	448	Shared Neighborhood Hits	81
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

ZCPW1_MOUSE
θ value	1.06291 (rank : 229)	NC score	0.115195 (rank : 150)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

ASH2L_HUMAN
θ value	1.38821 (rank : 230)	NC score	0.030843 (rank : 525)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

ASH2L_MOUSE
θ value	1.38821 (rank : 231)	NC score	0.031342 (rank : 522)
Query Neighborhood Hits	472	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

BRD4_HUMAN
θ value	1.38821 (rank : 232)	NC score	0.121256 (rank : 138)
Query Neighborhood Hits	472	Target Neighborhood Hits	851	Shared Neighborhood Hits	125
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CAF1B_MOUSE
θ value	1.38821 (rank : 233)	NC score	0.017955 (rank : 581)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

COKA1_HUMAN
θ value	1.38821 (rank : 234)	NC score	0.011051 (rank : 633)
Query Neighborhood Hits	472	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

EDEM3_HUMAN
θ value	1.38821 (rank : 235)	NC score	0.018352 (rank : 576)
Query Neighborhood Hits	472	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

FGD1_HUMAN
θ value	1.38821 (rank : 236)	NC score	0.026152 (rank : 540)
Query Neighborhood Hits	472	Target Neighborhood Hits	367	Shared Neighborhood Hits	45
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FYB_HUMAN
θ value	1.38821 (rank : 237)	NC score	0.084814 (rank : 220)
Query Neighborhood Hits	472	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GIPC2_MOUSE
θ value	1.38821 (rank : 238)	NC score	0.016154 (rank : 591)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

HLXB9_HUMAN
θ value	1.38821 (rank : 239)	NC score	0.000051 (rank : 672)
Query Neighborhood Hits	472	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	P50219, Q9Y648	Gene names	HLXB9
Domain Architecture
Description	Homeobox protein HB9.

LRC56_HUMAN
θ value	1.38821 (rank : 240)	NC score	0.032429 (rank : 516)
Query Neighborhood Hits	472	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

PHLPP_HUMAN
θ value	1.38821 (rank : 241)	NC score	0.016126 (rank : 593)
Query Neighborhood Hits	472	Target Neighborhood Hits	604	Shared Neighborhood Hits	61
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RIMB1_HUMAN
θ value	1.38821 (rank : 242)	NC score	0.044238 (rank : 473)
Query Neighborhood Hits	472	Target Neighborhood Hits	1479	Shared Neighborhood Hits	110
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RN125_MOUSE
θ value	1.38821 (rank : 243)	NC score	0.025778 (rank : 543)
Query Neighborhood Hits	472	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RUSC1_MOUSE
θ value	1.38821 (rank : 244)	NC score	0.045263 (rank : 471)
Query Neighborhood Hits	472	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SAPS1_HUMAN
θ value	1.38821 (rank : 245)	NC score	0.061426 (rank : 343)
Query Neighborhood Hits	472	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEZ6L_HUMAN
θ value	1.38821 (rank : 246)	NC score	0.028342 (rank : 537)
Query Neighborhood Hits	472	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

UHRF2_MOUSE
θ value	1.38821 (rank : 247)	NC score	0.192269 (rank : 100)
Query Neighborhood Hits	472	Target Neighborhood Hits	275	Shared Neighborhood Hits	77
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZAN_MOUSE
θ value	1.38821 (rank : 248)	NC score	0.052643 (rank : 421)
Query Neighborhood Hits	472	Target Neighborhood Hits	808	Shared Neighborhood Hits	59
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

3BP1_HUMAN
θ value	1.81305 (rank : 249)	NC score	0.049030 (rank : 456)
Query Neighborhood Hits	472	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AFAD_HUMAN
θ value	1.81305 (rank : 250)	NC score	0.023162 (rank : 553)
Query Neighborhood Hits	472	Target Neighborhood Hits	689	Shared Neighborhood Hits	40
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

AZI1_HUMAN
θ value	1.81305 (rank : 251)	NC score	0.018320 (rank : 579)
Query Neighborhood Hits	472	Target Neighborhood Hits	1000	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

DNM3B_HUMAN
θ value	1.81305 (rank : 252)	NC score	0.062506 (rank : 338)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

DNM3B_MOUSE
θ value	1.81305 (rank : 253)	NC score	0.055920 (rank : 392)
Query Neighborhood Hits	472	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

ENAM_HUMAN
θ value	1.81305 (rank : 254)	NC score	0.048543 (rank : 457)
Query Neighborhood Hits	472	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

GGN_MOUSE
θ value	1.81305 (rank : 255)	NC score	0.076942 (rank : 255)
Query Neighborhood Hits	472	Target Neighborhood Hits	311	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

K0423_MOUSE
θ value	1.81305 (rank : 256)	NC score	0.023094 (rank : 555)
Query Neighborhood Hits	472	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KI67_HUMAN
θ value	1.81305 (rank : 257)	NC score	0.099965 (rank : 176)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LPIN3_HUMAN
θ value	1.81305 (rank : 258)	NC score	0.014831 (rank : 599)
Query Neighborhood Hits	472	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

MDC1_HUMAN
θ value	1.81305 (rank : 259)	NC score	0.146235 (rank : 111)
Query Neighborhood Hits	472	Target Neighborhood Hits	1446	Shared Neighborhood Hits	194
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYCD_HUMAN
θ value	1.81305 (rank : 260)	NC score	0.037739 (rank : 500)
Query Neighborhood Hits	472	Target Neighborhood Hits	167	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

PO121_MOUSE
θ value	1.81305 (rank : 261)	NC score	0.061739 (rank : 341)
Query Neighborhood Hits	472	Target Neighborhood Hits	345	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RUFY1_HUMAN
θ value	1.81305 (rank : 262)	NC score	0.014652 (rank : 601)
Query Neighborhood Hits	472	Target Neighborhood Hits	848	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

VPS41_MOUSE
θ value	1.81305 (rank : 263)	NC score	0.031352 (rank : 521)
Query Neighborhood Hits	472	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

APC_HUMAN
θ value	2.36792 (rank : 264)	NC score	0.051329 (rank : 430)
Query Neighborhood Hits	472	Target Neighborhood Hits	603	Shared Neighborhood Hits	83
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ARI1A_HUMAN
θ value	2.36792 (rank : 265)	NC score	0.082899 (rank : 229)
Query Neighborhood Hits	472	Target Neighborhood Hits	787	Shared Neighborhood Hits	99
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BRD4_MOUSE
θ value	2.36792 (rank : 266)	NC score	0.125774 (rank : 130)
Query Neighborhood Hits	472	Target Neighborhood Hits	845	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CDN1B_MOUSE
θ value	2.36792 (rank : 267)	NC score	0.023113 (rank : 554)
Query Neighborhood Hits	472	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	P46414	Gene names	Cdkn1b
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

CEND_HUMAN
θ value	2.36792 (rank : 268)	NC score	0.049234 (rank : 454)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

DBF4_MOUSE
θ value	2.36792 (rank : 269)	NC score	0.020712 (rank : 566)
Query Neighborhood Hits	472	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

DYN2_MOUSE
θ value	2.36792 (rank : 270)	NC score	0.019397 (rank : 573)
Query Neighborhood Hits	472	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

GAK_HUMAN
θ value	2.36792 (rank : 271)	NC score	0.012220 (rank : 622)
Query Neighborhood Hits	472	Target Neighborhood Hits	1028	Shared Neighborhood Hits	48
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GCC2_MOUSE
θ value	2.36792 (rank : 272)	NC score	0.020862 (rank : 565)
Query Neighborhood Hits	472	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GTSE1_MOUSE
θ value	2.36792 (rank : 273)	NC score	0.063425 (rank : 329)
Query Neighborhood Hits	472	Target Neighborhood Hits	245	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

IF35_HUMAN
θ value	2.36792 (rank : 274)	NC score	0.034743 (rank : 509)
Query Neighborhood Hits	472	Target Neighborhood Hits	130	Shared Neighborhood Hits	27
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

MRC1_MOUSE
θ value	2.36792 (rank : 275)	NC score	0.010517 (rank : 636)
Query Neighborhood Hits	472	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

NOLC1_HUMAN
θ value	2.36792 (rank : 276)	NC score	0.110690 (rank : 160)
Query Neighborhood Hits	472	Target Neighborhood Hits	452	Shared Neighborhood Hits	95
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PHF20_HUMAN
θ value	2.36792 (rank : 277)	NC score	0.096701 (rank : 187)
Query Neighborhood Hits	472	Target Neighborhood Hits	394	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

RAI1_HUMAN
θ value	2.36792 (rank : 278)	NC score	0.133142 (rank : 119)
Query Neighborhood Hits	472	Target Neighborhood Hits	360	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RFIP1_HUMAN
θ value	2.36792 (rank : 279)	NC score	0.039930 (rank : 488)
Query Neighborhood Hits	472	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

SLC2B_HUMAN
θ value	2.36792 (rank : 280)	NC score	0.050810 (rank : 441)
Query Neighborhood Hits	472	Target Neighborhood Hits	214	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

TARA_MOUSE
θ value	2.36792 (rank : 281)	NC score	0.074487 (rank : 271)
Query Neighborhood Hits	472	Target Neighborhood Hits	1133	Shared Neighborhood Hits	127
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	2.36792 (rank : 282)	NC score	0.119388 (rank : 142)
Query Neighborhood Hits	472	Target Neighborhood Hits	768	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

THSD1_HUMAN
θ value	2.36792 (rank : 283)	NC score	0.025951 (rank : 541)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

AB1IP_HUMAN
θ value	3.0926 (rank : 284)	NC score	0.040762 (rank : 484)
Query Neighborhood Hits	472	Target Neighborhood Hits	213	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

AN32A_MOUSE
θ value	3.0926 (rank : 285)	NC score	0.016633 (rank : 587)
Query Neighborhood Hits	472	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
θ value	3.0926 (rank : 286)	NC score	0.016633 (rank : 588)
Query Neighborhood Hits	472	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

BCL9_HUMAN
θ value	3.0926 (rank : 287)	NC score	0.083912 (rank : 225)
Query Neighborhood Hits	472	Target Neighborhood Hits	1008	Shared Neighborhood Hits	134
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BRE1A_HUMAN
θ value	3.0926 (rank : 288)	NC score	0.014685 (rank : 600)
Query Neighborhood Hits	472	Target Neighborhood Hits	1071	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CENPF_HUMAN
θ value	3.0926 (rank : 289)	NC score	0.016469 (rank : 589)
Query Neighborhood Hits	472	Target Neighborhood Hits	1932	Shared Neighborhood Hits	117
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CYTSA_HUMAN
θ value	3.0926 (rank : 290)	NC score	0.013641 (rank : 613)
Query Neighborhood Hits	472	Target Neighborhood Hits	1138	Shared Neighborhood Hits	75
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DNM3L_MOUSE
θ value	3.0926 (rank : 291)	NC score	0.065916 (rank : 318)
Query Neighborhood Hits	472	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

DYN2_HUMAN
θ value	3.0926 (rank : 292)	NC score	0.018331 (rank : 578)
Query Neighborhood Hits	472	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

ENL_HUMAN
θ value	3.0926 (rank : 293)	NC score	0.067345 (rank : 306)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	63
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

FNBP2_HUMAN
θ value	3.0926 (rank : 294)	NC score	0.015299 (rank : 597)
Query Neighborhood Hits	472	Target Neighborhood Hits	432	Shared Neighborhood Hits	34
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GRIN1_HUMAN
θ value	3.0926 (rank : 295)	NC score	0.076428 (rank : 257)
Query Neighborhood Hits	472	Target Neighborhood Hits	681	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

HIF1A_MOUSE
θ value	3.0926 (rank : 296)	NC score	0.009636 (rank : 643)
Query Neighborhood Hits	472	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

LAD1_MOUSE
θ value	3.0926 (rank : 297)	NC score	0.117777 (rank : 146)
Query Neighborhood Hits	472	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LDB3_MOUSE
θ value	3.0926 (rank : 298)	NC score	0.032377 (rank : 517)
Query Neighborhood Hits	472	Target Neighborhood Hits	510	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

M4K4_MOUSE
θ value	3.0926 (rank : 299)	NC score	0.005751 (rank : 659)
Query Neighborhood Hits	472	Target Neighborhood Hits	1560	Shared Neighborhood Hits	72
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MK07_HUMAN
θ value	3.0926 (rank : 300)	NC score	0.012098 (rank : 623)
Query Neighborhood Hits	472	Target Neighborhood Hits	1087	Shared Neighborhood Hits	71
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MYCB2_HUMAN
θ value	3.0926 (rank : 301)	NC score	0.051053 (rank : 434)
Query Neighborhood Hits	472	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NOL8_HUMAN
θ value	3.0926 (rank : 302)	NC score	0.042040 (rank : 479)
Query Neighborhood Hits	472	Target Neighborhood Hits	297	Shared Neighborhood Hits	38
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

PHF14_HUMAN
θ value	3.0926 (rank : 303)	NC score	0.232833 (rank : 80)
Query Neighborhood Hits	472	Target Neighborhood Hits	447	Shared Neighborhood Hits	110
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	3.0926 (rank : 304)	NC score	0.237237 (rank : 79)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

SNAI_MOUSE
θ value	3.0926 (rank : 305)	NC score	-0.000629 (rank : 675)
Query Neighborhood Hits	472	Target Neighborhood Hits	696	Shared Neighborhood Hits	18
SwissProt Accessions	Q02085	Gene names	Snai1, Sna
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

SNX1_MOUSE
θ value	3.0926 (rank : 306)	NC score	0.009376 (rank : 646)
Query Neighborhood Hits	472	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

SORC3_MOUSE
θ value	3.0926 (rank : 307)	NC score	0.009536 (rank : 644)
Query Neighborhood Hits	472	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

TACC2_HUMAN
θ value	3.0926 (rank : 308)	NC score	0.035289 (rank : 507)
Query Neighborhood Hits	472	Target Neighborhood Hits	856	Shared Neighborhood Hits	81
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

TENS1_HUMAN
θ value	3.0926 (rank : 309)	NC score	0.036847 (rank : 503)
Query Neighborhood Hits	472	Target Neighborhood Hits	400	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TP53B_HUMAN
θ value	3.0926 (rank : 310)	NC score	0.061463 (rank : 342)
Query Neighborhood Hits	472	Target Neighborhood Hits	413	Shared Neighborhood Hits	68
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRIM8_MOUSE
θ value	3.0926 (rank : 311)	NC score	0.026392 (rank : 539)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

UBP35_HUMAN
θ value	3.0926 (rank : 312)	NC score	0.013442 (rank : 614)
Query Neighborhood Hits	472	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

XRCC1_MOUSE
θ value	3.0926 (rank : 313)	NC score	0.039372 (rank : 491)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZBT24_MOUSE
θ value	3.0926 (rank : 314)	NC score	-0.003123 (rank : 679)
Query Neighborhood Hits	472	Target Neighborhood Hits	894	Shared Neighborhood Hits	29
SwissProt Accessions	Q80X44, Q3UIB7, Q7TPC4, Q8CJC9	Gene names	Zbtb24, Bif1, Bsg1, Znf450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1).

ZN256_HUMAN
θ value	3.0926 (rank : 315)	NC score	-0.003824 (rank : 683)
Query Neighborhood Hits	472	Target Neighborhood Hits	748	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2P7, Q9BV71	Gene names	ZNF256, BMZF3
Domain Architecture	No domain graphic available
Description	Zinc finger protein 256 (Bone marrow zinc finger 3) (BMZF-3).

ZN746_MOUSE
θ value	3.0926 (rank : 316)	NC score	-0.000555 (rank : 673)
Query Neighborhood Hits	472	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

BMPER_HUMAN
θ value	4.03905 (rank : 317)	NC score	0.032618 (rank : 515)
Query Neighborhood Hits	472	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BSCL2_HUMAN
θ value	4.03905 (rank : 318)	NC score	0.025669 (rank : 544)
Query Neighborhood Hits	472	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

FA47B_HUMAN
θ value	4.03905 (rank : 319)	NC score	0.078962 (rank : 243)
Query Neighborhood Hits	472	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

FRAS1_MOUSE
θ value	4.03905 (rank : 320)	NC score	0.031886 (rank : 520)
Query Neighborhood Hits	472	Target Neighborhood Hits	747	Shared Neighborhood Hits	38
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GRAD_MOUSE
θ value	4.03905 (rank : 321)	NC score	0.001156 (rank : 670)
Query Neighborhood Hits	472	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

IF4G1_HUMAN
θ value	4.03905 (rank : 322)	NC score	0.039300 (rank : 493)
Query Neighborhood Hits	472	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ITB2_HUMAN
θ value	4.03905 (rank : 323)	NC score	0.012853 (rank : 619)
Query Neighborhood Hits	472	Target Neighborhood Hits	282	Shared Neighborhood Hits	17
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITIH3_HUMAN
θ value	4.03905 (rank : 324)	NC score	0.014268 (rank : 604)
Query Neighborhood Hits	472	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

MARCS_HUMAN
θ value	4.03905 (rank : 325)	NC score	0.077102 (rank : 254)
Query Neighborhood Hits	472	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

N4BP2_HUMAN
θ value	4.03905 (rank : 326)	NC score	0.030606 (rank : 526)
Query Neighborhood Hits	472	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

OPRM_HUMAN
θ value	4.03905 (rank : 327)	NC score	-0.008447 (rank : 684)
Query Neighborhood Hits	472	Target Neighborhood Hits	900	Shared Neighborhood Hits	2
SwissProt Accessions	P35372, Q12930, Q7Z2D8, Q9UCZ4, Q9UN57	Gene names	OPRM1, MOR1
Domain Architecture
Description	Mu-type opioid receptor (MOR-1).

PAIRB_HUMAN
θ value	4.03905 (rank : 328)	NC score	0.039714 (rank : 490)
Query Neighborhood Hits	472	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC51, Q8WUH0, Q96SE2, Q9BTY3, Q9BUM4, Q9Y367, Q9Y4S3	Gene names	SERBP1, PAIRBP1
Domain Architecture	No domain graphic available
Description	Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA- binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1).

PAIRB_MOUSE
θ value	4.03905 (rank : 329)	NC score	0.040250 (rank : 486)
Query Neighborhood Hits	472	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CY58, Q8BHS2, Q8BHU0, Q91WP3, Q9CSN0, Q9DBY6	Gene names	Serbp1, Pairbp1
Domain Architecture	No domain graphic available
Description	Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA- binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1).

PMS2_MOUSE
θ value	4.03905 (rank : 330)	NC score	0.019837 (rank : 572)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

PRR12_HUMAN
θ value	4.03905 (rank : 331)	NC score	0.086609 (rank : 212)
Query Neighborhood Hits	472	Target Neighborhood Hits	460	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PYGO2_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.080321 (rank : 237)
Query Neighborhood Hits	472	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RUFY1_MOUSE
θ value	4.03905 (rank : 333)	NC score	0.010078 (rank : 640)
Query Neighborhood Hits	472	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SGIP1_MOUSE
θ value	4.03905 (rank : 334)	NC score	0.051691 (rank : 427)
Query Neighborhood Hits	472	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYNG_HUMAN
θ value	4.03905 (rank : 335)	NC score	0.025244 (rank : 545)
Query Neighborhood Hits	472	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

TACC1_MOUSE
θ value	4.03905 (rank : 336)	NC score	0.051252 (rank : 431)
Query Neighborhood Hits	472	Target Neighborhood Hits	667	Shared Neighborhood Hits	63
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TAGAP_MOUSE
θ value	4.03905 (rank : 337)	NC score	0.013869 (rank : 606)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

ZBT17_HUMAN
θ value	4.03905 (rank : 338)	NC score	-0.003728 (rank : 682)
Query Neighborhood Hits	472	Target Neighborhood Hits	925	Shared Neighborhood Hits	32
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ZBTB1_HUMAN
θ value	4.03905 (rank : 339)	NC score	-0.002392 (rank : 677)
Query Neighborhood Hits	472	Target Neighborhood Hits	805	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2K1, Q86SW8	Gene names	ZBTB1, KIAA0997
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

AAKG2_HUMAN
θ value	5.27518 (rank : 340)	NC score	0.009440 (rank : 645)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

AN32A_HUMAN
θ value	5.27518 (rank : 341)	NC score	0.013122 (rank : 616)
Query Neighborhood Hits	472	Target Neighborhood Hits	234	Shared Neighborhood Hits	13
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

AUTS2_HUMAN
θ value	5.27518 (rank : 342)	NC score	0.053448 (rank : 416)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

BAT2_MOUSE
θ value	5.27518 (rank : 343)	NC score	0.075524 (rank : 264)
Query Neighborhood Hits	472	Target Neighborhood Hits	947	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BOC_HUMAN
θ value	5.27518 (rank : 344)	NC score	0.000141 (rank : 671)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CEP35_HUMAN
θ value	5.27518 (rank : 345)	NC score	0.038838 (rank : 496)
Query Neighborhood Hits	472	Target Neighborhood Hits	811	Shared Neighborhood Hits	78
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CO039_MOUSE
θ value	5.27518 (rank : 346)	NC score	0.069221 (rank : 296)
Query Neighborhood Hits	472	Target Neighborhood Hits	445	Shared Neighborhood Hits	86
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CXCC1_HUMAN
θ value	5.27518 (rank : 347)	NC score	0.115780 (rank : 148)
Query Neighborhood Hits	472	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	5.27518 (rank : 348)	NC score	0.113586 (rank : 154)
Query Neighborhood Hits	472	Target Neighborhood Hits	124	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

HCN4_HUMAN
θ value	5.27518 (rank : 349)	NC score	0.019374 (rank : 574)
Query Neighborhood Hits	472	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HS105_HUMAN
θ value	5.27518 (rank : 350)	NC score	0.011942 (rank : 625)
Query Neighborhood Hits	472	Target Neighborhood Hits	209	Shared Neighborhood Hits	27
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

HUWE1_HUMAN
θ value	5.27518 (rank : 351)	NC score	0.029618 (rank : 529)
Query Neighborhood Hits	472	Target Neighborhood Hits	443	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

IF39_MOUSE
θ value	5.27518 (rank : 352)	NC score	0.028464 (rank : 536)
Query Neighborhood Hits	472	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

IYD1_MOUSE
θ value	5.27518 (rank : 353)	NC score	0.015379 (rank : 596)
Query Neighborhood Hits	472	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCX8	Gene names	Iyd, Dehal1
Domain Architecture	No domain graphic available
Description	Iodotyrosine dehalogenase 1 precursor (EC 1.-.-.-) (IYD-1).

LRP1B_HUMAN
θ value	5.27518 (rank : 354)	NC score	0.005058 (rank : 660)
Query Neighborhood Hits	472	Target Neighborhood Hits	602	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEFV_HUMAN
θ value	5.27518 (rank : 355)	NC score	0.011863 (rank : 627)
Query Neighborhood Hits	472	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MKL2_HUMAN
θ value	5.27518 (rank : 356)	NC score	0.040043 (rank : 487)
Query Neighborhood Hits	472	Target Neighborhood Hits	274	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MKL2_MOUSE
θ value	5.27518 (rank : 357)	NC score	0.040935 (rank : 482)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

NEST_HUMAN
θ value	5.27518 (rank : 358)	NC score	0.038752 (rank : 497)
Query Neighborhood Hits	472	Target Neighborhood Hits	1305	Shared Neighborhood Hits	108
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NNP1_HUMAN
θ value	5.27518 (rank : 359)	NC score	0.013337 (rank : 615)
Query Neighborhood Hits	472	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P56182, Q9NST5	Gene names	NNP1, NOP52
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nucleolar protein Nop52) (D21S2056E).

PHLB1_HUMAN
θ value	5.27518 (rank : 360)	NC score	0.037818 (rank : 499)
Query Neighborhood Hits	472	Target Neighborhood Hits	1038	Shared Neighborhood Hits	100
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PRDM7_HUMAN
θ value	5.27518 (rank : 361)	NC score	-0.003676 (rank : 681)
Query Neighborhood Hits	472	Target Neighborhood Hits	697	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQW5, Q9NQW4	Gene names	PRDM7, PFM4
Domain Architecture
Description	PR domain zinc finger protein 7 (PR domain-containing protein 7).

PRPF3_HUMAN
θ value	5.27518 (rank : 362)	NC score	0.020889 (rank : 564)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

PRPF3_MOUSE
θ value	5.27518 (rank : 363)	NC score	0.021843 (rank : 560)
Query Neighborhood Hits	472	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

REN3A_HUMAN
θ value	5.27518 (rank : 364)	NC score	0.021194 (rank : 563)
Query Neighborhood Hits	472	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

RGS3_HUMAN
θ value	5.27518 (rank : 365)	NC score	0.077781 (rank : 249)
Query Neighborhood Hits	472	Target Neighborhood Hits	1375	Shared Neighborhood Hits	153
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

S6A16_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.002716 (rank : 666)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZN6, Q9Y5I9	Gene names	SLC6A16, NTT5
Domain Architecture
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16).

SEPT9_MOUSE
θ value	5.27518 (rank : 367)	NC score	0.020433 (rank : 570)
Query Neighborhood Hits	472	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

SMYD5_MOUSE
θ value	5.27518 (rank : 368)	NC score	0.030486 (rank : 527)
Query Neighborhood Hits	472	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

TACC2_MOUSE
θ value	5.27518 (rank : 369)	NC score	0.034450 (rank : 512)
Query Neighborhood Hits	472	Target Neighborhood Hits	774	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

TCF20_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.124302 (rank : 132)
Query Neighborhood Hits	472	Target Neighborhood Hits	323	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TEX15_HUMAN
θ value	5.27518 (rank : 371)	NC score	0.032228 (rank : 519)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

TNNI3_MOUSE
θ value	5.27518 (rank : 372)	NC score	0.012743 (rank : 620)
Query Neighborhood Hits	472	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P48787	Gene names	Tnni3
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

ZCH10_HUMAN
θ value	5.27518 (rank : 373)	NC score	0.030873 (rank : 524)
Query Neighborhood Hits	472	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ZNFX1_HUMAN
θ value	5.27518 (rank : 374)	NC score	0.027162 (rank : 538)
Query Neighborhood Hits	472	Target Neighborhood Hits	308	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZYX_HUMAN
θ value	5.27518 (rank : 375)	NC score	0.034833 (rank : 508)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	54
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

ACD_MOUSE
θ value	6.88961 (rank : 376)	NC score	0.013829 (rank : 609)
Query Neighborhood Hits	472	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q5EE38, Q3TBB1, Q3TUR7, Q3UKL6, Q3V3Y1, Q99KF8	Gene names	Acd
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein.

AKAP4_MOUSE
θ value	6.88961 (rank : 377)	NC score	0.008045 (rank : 651)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q60662, Q60630, Q8R2G7	Gene names	Akap4, Akap82, Fsc1
Domain Architecture
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (mAKAP82) (Major sperm fibrous sheath protein) (FSC1) (p82).

AP3B1_MOUSE
θ value	6.88961 (rank : 378)	NC score	0.024508 (rank : 547)
Query Neighborhood Hits	472	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3D1_MOUSE
θ value	6.88961 (rank : 379)	NC score	0.013814 (rank : 611)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

APLP1_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.010567 (rank : 635)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

BLNK_MOUSE
θ value	6.88961 (rank : 381)	NC score	0.047673 (rank : 461)
Query Neighborhood Hits	472	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

CD2L1_HUMAN
θ value	6.88961 (rank : 382)	NC score	0.007963 (rank : 652)
Query Neighborhood Hits	472	Target Neighborhood Hits	1467	Shared Neighborhood Hits	69
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CD4_HUMAN
θ value	6.88961 (rank : 383)	NC score	0.009820 (rank : 641)
Query Neighborhood Hits	472	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

CHD8_HUMAN
θ value	6.88961 (rank : 384)	NC score	0.071802 (rank : 282)
Query Neighborhood Hits	472	Target Neighborhood Hits	235	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CIC_MOUSE
θ value	6.88961 (rank : 385)	NC score	0.049183 (rank : 455)
Query Neighborhood Hits	472	Target Neighborhood Hits	742	Shared Neighborhood Hits	109
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DCHS_HUMAN
θ value	6.88961 (rank : 386)	NC score	0.006594 (rank : 656)
Query Neighborhood Hits	472	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

DGC14_MOUSE
θ value	6.88961 (rank : 387)	NC score	0.016137 (rank : 592)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

DOK7_HUMAN
θ value	6.88961 (rank : 388)	NC score	0.013857 (rank : 607)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DOT1L_HUMAN
θ value	6.88961 (rank : 389)	NC score	0.057318 (rank : 377)
Query Neighborhood Hits	472	Target Neighborhood Hits	660	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FARP2_HUMAN
θ value	6.88961 (rank : 390)	NC score	0.010308 (rank : 638)
Query Neighborhood Hits	472	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GAK_MOUSE
θ value	6.88961 (rank : 391)	NC score	0.008925 (rank : 648)
Query Neighborhood Hits	472	Target Neighborhood Hits	964	Shared Neighborhood Hits	41
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GNAS1_MOUSE
θ value	6.88961 (rank : 392)	NC score	0.034717 (rank : 510)
Query Neighborhood Hits	472	Target Neighborhood Hits	651	Shared Neighborhood Hits	87
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

GP156_HUMAN
θ value	6.88961 (rank : 393)	NC score	0.014962 (rank : 598)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

HDAC6_HUMAN
θ value	6.88961 (rank : 394)	NC score	0.017932 (rank : 582)
Query Neighborhood Hits	472	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

IF4B_HUMAN
θ value	6.88961 (rank : 395)	NC score	0.036279 (rank : 506)
Query Neighborhood Hits	472	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

JHD3C_MOUSE
θ value	6.88961 (rank : 396)	NC score	0.110919 (rank : 158)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

LRC27_HUMAN
θ value	6.88961 (rank : 397)	NC score	0.020643 (rank : 567)
Query Neighborhood Hits	472	Target Neighborhood Hits	710	Shared Neighborhood Hits	47
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

M3KL4_HUMAN
θ value	6.88961 (rank : 398)	NC score	-0.000595 (rank : 674)
Query Neighborhood Hits	472	Target Neighborhood Hits	1087	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MAP4_MOUSE
θ value	6.88961 (rank : 399)	NC score	0.082381 (rank : 232)
Query Neighborhood Hits	472	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MSH6_MOUSE
θ value	6.88961 (rank : 400)	NC score	0.055085 (rank : 400)
Query Neighborhood Hits	472	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

NOTC2_MOUSE
θ value	6.88961 (rank : 401)	NC score	0.024182 (rank : 548)
Query Neighborhood Hits	472	Target Neighborhood Hits	1069	Shared Neighborhood Hits	62
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PANK1_HUMAN
θ value	6.88961 (rank : 402)	NC score	0.008354 (rank : 650)
Query Neighborhood Hits	472	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

PARM1_MOUSE
θ value	6.88961 (rank : 403)	NC score	0.039337 (rank : 492)
Query Neighborhood Hits	472	Target Neighborhood Hits	140	Shared Neighborhood Hits	23
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

PHF6_HUMAN
θ value	6.88961 (rank : 404)	NC score	0.122181 (rank : 137)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	6.88961 (rank : 405)	NC score	0.118254 (rank : 144)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PSD4_HUMAN
θ value	6.88961 (rank : 406)	NC score	0.022396 (rank : 558)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

RBM16_HUMAN
θ value	6.88961 (rank : 407)	NC score	0.034472 (rank : 511)
Query Neighborhood Hits	472	Target Neighborhood Hits	300	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RBM25_HUMAN
θ value	6.88961 (rank : 408)	NC score	0.029258 (rank : 534)
Query Neighborhood Hits	472	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RTN4_HUMAN
θ value	6.88961 (rank : 409)	NC score	0.045272 (rank : 470)
Query Neighborhood Hits	472	Target Neighborhood Hits	357	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SETBP_HUMAN
θ value	6.88961 (rank : 410)	NC score	0.046553 (rank : 467)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SMYD1_HUMAN
θ value	6.88961 (rank : 411)	NC score	0.024744 (rank : 546)
Query Neighborhood Hits	472	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD1_MOUSE
θ value	6.88961 (rank : 412)	NC score	0.023731 (rank : 550)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

STAR8_MOUSE
θ value	6.88961 (rank : 413)	NC score	0.009238 (rank : 647)
Query Neighborhood Hits	472	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

TNNI3_HUMAN
θ value	6.88961 (rank : 414)	NC score	0.012093 (rank : 624)
Query Neighborhood Hits	472	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	P19429	Gene names	TNNI3, TNNC1
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

TRI25_HUMAN
θ value	6.88961 (rank : 415)	NC score	0.020558 (rank : 569)
Query Neighborhood Hits	472	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRIPC_HUMAN
θ value	6.88961 (rank : 416)	NC score	0.032254 (rank : 518)
Query Neighborhood Hits	472	Target Neighborhood Hits	319	Shared Neighborhood Hits	57
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ZN555_HUMAN
θ value	6.88961 (rank : 417)	NC score	-0.003279 (rank : 680)
Query Neighborhood Hits	472	Target Neighborhood Hits	741	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEP9, Q8NA46, Q96MP1	Gene names	ZNF555
Domain Architecture	No domain graphic available
Description	Zinc finger protein 555.

ANK1_MOUSE
θ value	8.99809 (rank : 418)	NC score	0.029534 (rank : 530)
Query Neighborhood Hits	472	Target Neighborhood Hits	430	Shared Neighborhood Hits	23
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ARVC_HUMAN
θ value	8.99809 (rank : 419)	NC score	0.004945 (rank : 661)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

BCL6_HUMAN
θ value	8.99809 (rank : 420)	NC score	-0.000902 (rank : 676)
Query Neighborhood Hits	472	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

BRWD1_HUMAN
θ value	8.99809 (rank : 421)	NC score	0.043177 (rank : 475)
Query Neighborhood Hits	472	Target Neighborhood Hits	448	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

BSN_HUMAN
θ value	8.99809 (rank : 422)	NC score	0.077543 (rank : 251)
Query Neighborhood Hits	472	Target Neighborhood Hits	1537	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCNT2_HUMAN
θ value	8.99809 (rank : 423)	NC score	0.011507 (rank : 630)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

CD68_MOUSE
θ value	8.99809 (rank : 424)	NC score	0.013896 (rank : 605)
Query Neighborhood Hits	472	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

CIC_HUMAN
θ value	8.99809 (rank : 425)	NC score	0.056143 (rank : 388)
Query Neighborhood Hits	472	Target Neighborhood Hits	992	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CN004_MOUSE
θ value	8.99809 (rank : 426)	NC score	0.016982 (rank : 586)
Query Neighborhood Hits	472	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

CO002_HUMAN
θ value	8.99809 (rank : 427)	NC score	0.075208 (rank : 269)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CO5A2_HUMAN
θ value	8.99809 (rank : 428)	NC score	0.023443 (rank : 551)
Query Neighborhood Hits	472	Target Neighborhood Hits	760	Shared Neighborhood Hits	69
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CT112_MOUSE
θ value	8.99809 (rank : 429)	NC score	0.020641 (rank : 568)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

FA47A_HUMAN
θ value	8.99809 (rank : 430)	NC score	0.084290 (rank : 221)
Query Neighborhood Hits	472	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FBXL2_MOUSE
θ value	8.99809 (rank : 431)	NC score	0.010596 (rank : 634)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FLIP1_HUMAN
θ value	8.99809 (rank : 432)	NC score	0.011428 (rank : 631)
Query Neighborhood Hits	472	Target Neighborhood Hits	1405	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FYV1_MOUSE
θ value	8.99809 (rank : 433)	NC score	0.011624 (rank : 628)
Query Neighborhood Hits	472	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GET1_HUMAN
θ value	8.99809 (rank : 434)	NC score	0.010430 (rank : 637)
Query Neighborhood Hits	472	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95210	Gene names	ames=GENX-3414
Domain Architecture
Description	Genethonin-1.

GSCR1_HUMAN
θ value	8.99809 (rank : 435)	NC score	0.100992 (rank : 175)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IF2P_HUMAN
θ value	8.99809 (rank : 436)	NC score	0.034278 (rank : 513)
Query Neighborhood Hits	472	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

INVS_MOUSE
θ value	8.99809 (rank : 437)	NC score	0.047970 (rank : 458)
Query Neighborhood Hits	472	Target Neighborhood Hits	609	Shared Neighborhood Hits	75
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

JHD2B_HUMAN
θ value	8.99809 (rank : 438)	NC score	0.011885 (rank : 626)
Query Neighborhood Hits	472	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

K0310_HUMAN
θ value	8.99809 (rank : 439)	NC score	0.054522 (rank : 408)
Query Neighborhood Hits	472	Target Neighborhood Hits	420	Shared Neighborhood Hits	57
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

K0423_HUMAN
θ value	8.99809 (rank : 440)	NC score	0.039721 (rank : 489)
Query Neighborhood Hits	472	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K1333_MOUSE
θ value	8.99809 (rank : 441)	NC score	0.105395 (rank : 169)
Query Neighborhood Hits	472	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LIPA3_MOUSE
θ value	8.99809 (rank : 442)	NC score	0.007101 (rank : 654)
Query Neighborhood Hits	472	Target Neighborhood Hits	636	Shared Neighborhood Hits	39
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRP1B_MOUSE
θ value	8.99809 (rank : 443)	NC score	0.006871 (rank : 655)
Query Neighborhood Hits	472	Target Neighborhood Hits	606	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	8.99809 (rank : 444)	NC score	0.004873 (rank : 662)
Query Neighborhood Hits	472	Target Neighborhood Hits	617	Shared Neighborhood Hits	20
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MCRS1_HUMAN
θ value	8.99809 (rank : 445)	NC score	0.010192 (rank : 639)
Query Neighborhood Hits	472	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EZ8, O14742, O75497, Q6VN53	Gene names	MCRS1, MSP58
Domain Architecture
Description	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle- regulated factor p78) (MCRS2).

NASP_HUMAN
θ value	8.99809 (rank : 446)	NC score	0.070120 (rank : 293)
Query Neighborhood Hits	472	Target Neighborhood Hits	709	Shared Neighborhood Hits	78
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NFRKB_HUMAN
θ value	8.99809 (rank : 447)	NC score	0.047253 (rank : 463)
Query Neighborhood Hits	472	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NKTR_HUMAN
θ value	8.99809 (rank : 448)	NC score	0.047814 (rank : 459)
Query Neighborhood Hits	472	Target Neighborhood Hits	658	Shared Neighborhood Hits	85
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NOTC2_HUMAN
θ value	8.99809 (rank : 449)	NC score	0.028788 (rank : 535)
Query Neighborhood Hits	472	Target Neighborhood Hits	1113	Shared Neighborhood Hits	86
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PHC2_MOUSE
θ value	8.99809 (rank : 450)	NC score	0.021550 (rank : 562)
Query Neighborhood Hits	472	Target Neighborhood Hits	156	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

PI5PA_HUMAN
θ value	8.99809 (rank : 451)	NC score	0.063128 (rank : 330)
Query Neighborhood Hits	472	Target Neighborhood Hits	749	Shared Neighborhood Hits	123
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PIWL2_MOUSE
θ value	8.99809 (rank : 452)	NC score	0.004490 (rank : 663)
Query Neighborhood Hits	472	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

POP1_HUMAN
θ value	8.99809 (rank : 453)	NC score	0.013823 (rank : 610)
Query Neighborhood Hits	472	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

PSMD2_HUMAN
θ value	8.99809 (rank : 454)	NC score	0.011225 (rank : 632)
Query Neighborhood Hits	472	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

PSMD2_MOUSE
θ value	8.99809 (rank : 455)	NC score	0.013848 (rank : 608)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

PTN22_MOUSE
θ value	8.99809 (rank : 456)	NC score	0.009780 (rank : 642)
Query Neighborhood Hits	472	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

S23IP_MOUSE
θ value	8.99809 (rank : 457)	NC score	0.042300 (rank : 478)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SFR11_HUMAN
θ value	8.99809 (rank : 458)	NC score	0.074325 (rank : 272)
Query Neighborhood Hits	472	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_MOUSE
θ value	8.99809 (rank : 459)	NC score	0.043064 (rank : 476)
Query Neighborhood Hits	472	Target Neighborhood Hits	486	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SHAN2_MOUSE
θ value	8.99809 (rank : 460)	NC score	0.018740 (rank : 575)
Query Neighborhood Hits	472	Target Neighborhood Hits	446	Shared Neighborhood Hits	43
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SMYD3_HUMAN
θ value	8.99809 (rank : 461)	NC score	0.057350 (rank : 376)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
θ value	8.99809 (rank : 462)	NC score	0.056377 (rank : 385)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SYN1_HUMAN
θ value	8.99809 (rank : 463)	NC score	0.069537 (rank : 294)
Query Neighborhood Hits	472	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SYTL2_MOUSE
θ value	8.99809 (rank : 464)	NC score	0.015612 (rank : 594)
Query Neighborhood Hits	472	Target Neighborhood Hits	253	Shared Neighborhood Hits	32
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

TFP11_MOUSE
θ value	8.99809 (rank : 465)	NC score	0.017566 (rank : 584)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

THAP4_MOUSE
θ value	8.99809 (rank : 466)	NC score	0.016232 (rank : 590)
Query Neighborhood Hits	472	Target Neighborhood Hits	130	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

TTBK1_HUMAN
θ value	8.99809 (rank : 467)	NC score	0.020177 (rank : 571)
Query Neighborhood Hits	472	Target Neighborhood Hits	1058	Shared Neighborhood Hits	74
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

USH2A_MOUSE
θ value	8.99809 (rank : 468)	NC score	0.007514 (rank : 653)
Query Neighborhood Hits	472	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VWF_MOUSE
θ value	8.99809 (rank : 469)	NC score	0.029346 (rank : 532)
Query Neighborhood Hits	472	Target Neighborhood Hits	381	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZCH14_MOUSE
θ value	8.99809 (rank : 470)	NC score	0.024082 (rank : 549)
Query Neighborhood Hits	472	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZFP37_MOUSE
θ value	8.99809 (rank : 471)	NC score	-0.002528 (rank : 678)
Query Neighborhood Hits	472	Target Neighborhood Hits	906	Shared Neighborhood Hits	52
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZIMP7_HUMAN
θ value	8.99809 (rank : 472)	NC score	0.023330 (rank : 552)
Query Neighborhood Hits	472	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ACINU_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.075370 (rank : 267)
Query Neighborhood Hits	472	Target Neighborhood Hits	828	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ADDB_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.059037 (rank : 365)
Query Neighborhood Hits	472	Target Neighborhood Hits	574	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

AFF1_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.065999 (rank : 316)
Query Neighborhood Hits	472	Target Neighborhood Hits	506	Shared Neighborhood Hits	87
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF4_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.059768 (rank : 358)
Query Neighborhood Hits	472	Target Neighborhood Hits	611	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.060792 (rank : 347)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AKA12_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.082350 (rank : 233)
Query Neighborhood Hits	472	Target Neighborhood Hits	825	Shared Neighborhood Hits	103
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ALEX_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.069427 (rank : 295)
Query Neighborhood Hits	472	Target Neighborhood Hits	361	Shared Neighborhood Hits	73
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

ANR11_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.062024 (rank : 339)
Query Neighborhood Hits	472	Target Neighborhood Hits	1289	Shared Neighborhood Hits	148
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ARI1B_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.064782 (rank : 320)
Query Neighborhood Hits	472	Target Neighborhood Hits	567	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARI5B_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.056217 (rank : 387)
Query Neighborhood Hits	472	Target Neighborhood Hits	328	Shared Neighborhood Hits	68
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ASPP1_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.055531 (rank : 396)
Query Neighborhood Hits	472	Target Neighborhood Hits	1244	Shared Neighborhood Hits	127
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAG3_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.071007 (rank : 286)
Query Neighborhood Hits	472	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

BASP_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.086373 (rank : 213)
Query Neighborhood Hits	472	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BASP_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.060439 (rank : 350)
Query Neighborhood Hits	472	Target Neighborhood Hits	260	Shared Neighborhood Hits	44
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.068079 (rank : 304)
Query Neighborhood Hits	472	Target Neighborhood Hits	931	Shared Neighborhood Hits	124
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.073287 (rank : 279)
Query Neighborhood Hits	472	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BRD2_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.092303 (rank : 195)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.088736 (rank : 207)
Query Neighborhood Hits	472	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.091513 (rank : 196)
Query Neighborhood Hits	472	Target Neighborhood Hits	402	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD7_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.067032 (rank : 310)
Query Neighborhood Hits	472	Target Neighborhood Hits	94	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.062726 (rank : 332)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD8_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.095646 (rank : 189)
Query Neighborhood Hits	472	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.112205 (rank : 156)
Query Neighborhood Hits	472	Target Neighborhood Hits	422	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRD9_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.062692 (rank : 333)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

BRD9_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.067203 (rank : 307)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

BRDT_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.080038 (rank : 238)
Query Neighborhood Hits	472	Target Neighborhood Hits	280	Shared Neighborhood Hits	44
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.083835 (rank : 226)
Query Neighborhood Hits	472	Target Neighborhood Hits	243	Shared Neighborhood Hits	56
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BSN_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.097030 (rank : 183)
Query Neighborhood Hits	472	Target Neighborhood Hits	2057	Shared Neighborhood Hits	195
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BTAF1_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.054748 (rank : 404)
Query Neighborhood Hits	472	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CABIN_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.055264 (rank : 398)
Query Neighborhood Hits	472	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CASC3_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.052974 (rank : 418)
Query Neighborhood Hits	472	Target Neighborhood Hits	333	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CBP_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.114753 (rank : 151)
Query Neighborhood Hits	472	Target Neighborhood Hits	941	Shared Neighborhood Hits	144
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBX1_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.059500 (rank : 361)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.059500 (rank : 362)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX2_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.050997 (rank : 437)
Query Neighborhood Hits	472	Target Neighborhood Hits	264	Shared Neighborhood Hits	45
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX3_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.068119 (rank : 303)
Query Neighborhood Hits	472	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.068587 (rank : 301)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.065934 (rank : 317)
Query Neighborhood Hits	472	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.063858 (rank : 326)
Query Neighborhood Hits	472	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CCNK_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.053574 (rank : 415)
Query Neighborhood Hits	472	Target Neighborhood Hits	350	Shared Neighborhood Hits	56
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CD2_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.056471 (rank : 384)
Query Neighborhood Hits	472	Target Neighborhood Hits	504	Shared Neighborhood Hits	60
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CECR2_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.108610 (rank : 164)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD1_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.077921 (rank : 247)
Query Neighborhood Hits	472	Target Neighborhood Hits	337	Shared Neighborhood Hits	45
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.074946 (rank : 270)
Query Neighborhood Hits	472	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.078538 (rank : 245)
Query Neighborhood Hits	472	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.079121 (rank : 242)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD9_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.075401 (rank : 266)
Query Neighborhood Hits	472	Target Neighborhood Hits	343	Shared Neighborhood Hits	51
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.077505 (rank : 252)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CIZ1_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.056611 (rank : 381)
Query Neighborhood Hits	472	Target Neighborhood Hits	359	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CJ012_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.089519 (rank : 205)
Query Neighborhood Hits	472	Target Neighborhood Hits	467	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CJ078_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.082989 (rank : 228)
Query Neighborhood Hits	472	Target Neighborhood Hits	559	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

CK024_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.069010 (rank : 298)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	81
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CK024_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.052872 (rank : 420)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CN032_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.050702 (rank : 443)
Query Neighborhood Hits	472	Target Neighborhood Hits	267	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.054469 (rank : 409)
Query Neighborhood Hits	472	Target Neighborhood Hits	233	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

CN155_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.086182 (rank : 214)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	80
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CRSP7_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.053381 (rank : 417)
Query Neighborhood Hits	472	Target Neighborhood Hits	247	Shared Neighborhood Hits	39
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CSKI1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.050871 (rank : 440)
Query Neighborhood Hits	472	Target Neighborhood Hits	997	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.054037 (rank : 412)
Query Neighborhood Hits	472	Target Neighborhood Hits	1031	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_HUMAN
θ value	θ > 10 (rank : 532)	NC score	0.050020 (rank : 452)
Query Neighborhood Hits	472	Target Neighborhood Hits	747	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT174_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.060946 (rank : 345)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

DIDO1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.098401 (rank : 181)
Query Neighborhood Hits	472	Target Neighborhood Hits	960	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

DMP1_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.070982 (rank : 287)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.056589 (rank : 382)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DNMT1_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.067682 (rank : 305)
Query Neighborhood Hits	472	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DPF3_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.051845 (rank : 426)
Query Neighborhood Hits	472	Target Neighborhood Hits	327	Shared Neighborhood Hits	16
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EMSY_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.052029 (rank : 423)
Query Neighborhood Hits	472	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ENAH_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.056018 (rank : 390)
Query Neighborhood Hits	472	Target Neighborhood Hits	919	Shared Neighborhood Hits	96
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP300_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.116585 (rank : 147)
Query Neighborhood Hits	472	Target Neighborhood Hits	821	Shared Neighborhood Hits	122
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

EP400_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.076328 (rank : 259)
Query Neighborhood Hits	472	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.082815 (rank : 230)
Query Neighborhood Hits	472	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.064467 (rank : 322)
Query Neighborhood Hits	472	Target Neighborhood Hits	247	Shared Neighborhood Hits	24
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

FXL19_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.050152 (rank : 448)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

GCNL2_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.085835 (rank : 216)
Query Neighborhood Hits	472	Target Neighborhood Hits	159	Shared Neighborhood Hits	43
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.084236 (rank : 223)
Query Neighborhood Hits	472	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GGN_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.060489 (rank : 349)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GON4L_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.053884 (rank : 413)
Query Neighborhood Hits	472	Target Neighborhood Hits	555	Shared Neighborhood Hits	84
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GRIN1_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.055006 (rank : 403)
Query Neighborhood Hits	472	Target Neighborhood Hits	337	Shared Neighborhood Hits	70
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

INGX_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.106597 (rank : 167)
Query Neighborhood Hits	472	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

INOC1_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.057077 (rank : 379)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.057228 (rank : 378)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

IWS1_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.115359 (rank : 149)
Query Neighborhood Hits	472	Target Neighborhood Hits	1241	Shared Neighborhood Hits	167
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.124212 (rank : 133)
Query Neighborhood Hits	472	Target Neighborhood Hits	1258	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JHD3A_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.104398 (rank : 172)
Query Neighborhood Hits	472	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.106791 (rank : 166)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.104228 (rank : 173)
Query Neighborhood Hits	472	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.109054 (rank : 163)
Query Neighborhood Hits	472	Target Neighborhood Hits	152	Shared Neighborhood Hits	53
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

K1333_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.089220 (rank : 206)
Query Neighborhood Hits	472	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1543_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.052905 (rank : 419)
Query Neighborhood Hits	472	Target Neighborhood Hits	497	Shared Neighborhood Hits	85
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LCP2_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.056091 (rank : 389)
Query Neighborhood Hits	472	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

LEO1_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.068763 (rank : 299)
Query Neighborhood Hits	472	Target Neighborhood Hits	958	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.076936 (rank : 256)
Query Neighborhood Hits	472	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LR37A_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.061901 (rank : 340)
Query Neighborhood Hits	472	Target Neighborhood Hits	720	Shared Neighborhood Hits	93
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MAP1B_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.082635 (rank : 231)
Query Neighborhood Hits	472	Target Neighborhood Hits	977	Shared Neighborhood Hits	124
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP2_MOUSE
θ value	θ > 10 (rank : 567)	NC score	0.050610 (rank : 444)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	67
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MAP4_HUMAN
θ value	θ > 10 (rank : 568)	NC score	0.076066 (rank : 261)
Query Neighborhood Hits	472	Target Neighborhood Hits	428	Shared Neighborhood Hits	91
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MARCS_MOUSE
θ value	θ > 10 (rank : 569)	NC score	0.051111 (rank : 433)
Query Neighborhood Hits	472	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MAVS_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.067094 (rank : 309)
Query Neighborhood Hits	472	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MBB1A_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.066329 (rank : 312)
Query Neighborhood Hits	472	Target Neighborhood Hits	665	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD6_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.075528 (rank : 263)
Query Neighborhood Hits	472	Target Neighborhood Hits	349	Shared Neighborhood Hits	65
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MDC1_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.136246 (rank : 116)
Query Neighborhood Hits	472	Target Neighborhood Hits	998	Shared Neighborhood Hits	167
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MILK1_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.058828 (rank : 366)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
θ value	θ > 10 (rank : 575)	NC score	0.058776 (rank : 367)
Query Neighborhood Hits	472	Target Neighborhood Hits	788	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.080904 (rank : 236)
Query Neighborhood Hits	472	Target Neighborhood Hits	1514	Shared Neighborhood Hits	180
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MPP8_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.079294 (rank : 240)
Query Neighborhood Hits	472	Target Neighborhood Hits	948	Shared Neighborhood Hits	99
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MSH6_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.052279 (rank : 422)
Query Neighborhood Hits	472	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MTF2_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.128232 (rank : 125)
Query Neighborhood Hits	472	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.128801 (rank : 124)
Query Neighborhood Hits	472	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MUC13_MOUSE
θ value	θ > 10 (rank : 581)	NC score	0.059552 (rank : 359)
Query Neighborhood Hits	472	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.077868 (rank : 248)
Query Neighborhood Hits	472	Target Neighborhood Hits	975	Shared Neighborhood Hits	128
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC1_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.068371 (rank : 302)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	67
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MUC2_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.079197 (rank : 241)
Query Neighborhood Hits	472	Target Neighborhood Hits	906	Shared Neighborhood Hits	104
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.096904 (rank : 185)
Query Neighborhood Hits	472	Target Neighborhood Hits	538	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYST1_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.055070 (rank : 401)
Query Neighborhood Hits	472	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.055015 (rank : 402)
Query Neighborhood Hits	472	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

MYST2_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.057574 (rank : 375)
Query Neighborhood Hits	472	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.057781 (rank : 374)
Query Neighborhood Hits	472	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

NSBP1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.060718 (rank : 348)
Query Neighborhood Hits	472	Target Neighborhood Hits	681	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NU214_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.059227 (rank : 363)
Query Neighborhood Hits	472	Target Neighborhood Hits	657	Shared Neighborhood Hits	93
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OGFR_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.090279 (rank : 199)
Query Neighborhood Hits	472	Target Neighborhood Hits	1582	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

OGFR_MOUSE
θ value	θ > 10 (rank : 593)	NC score	0.064551 (rank : 321)
Query Neighborhood Hits	472	Target Neighborhood Hits	584	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PB1_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.075277 (rank : 268)
Query Neighborhood Hits	472	Target Neighborhood Hits	261	Shared Neighborhood Hits	41
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.079841 (rank : 239)
Query Neighborhood Hits	472	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PCQAP_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.051998 (rank : 425)
Query Neighborhood Hits	472	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PELP1_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.050036 (rank : 451)
Query Neighborhood Hits	472	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PHF11_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.123611 (rank : 134)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF1_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.120549 (rank : 140)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.119777 (rank : 141)
Query Neighborhood Hits	472	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF22_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.095270 (rank : 191)
Query Neighborhood Hits	472	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.097365 (rank : 182)
Query Neighborhood Hits	472	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF2_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.056875 (rank : 380)
Query Neighborhood Hits	472	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.060087 (rank : 355)
Query Neighborhood Hits	472	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF3_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.051023 (rank : 435)
Query Neighborhood Hits	472	Target Neighborhood Hits	419	Shared Neighborhood Hits	62
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PML_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.065814 (rank : 319)
Query Neighborhood Hits	472	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.058172 (rank : 372)
Query Neighborhood Hits	472	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

PO121_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.062592 (rank : 337)
Query Neighborhood Hits	472	Target Neighborhood Hits	344	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PPRB_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.050703 (rank : 442)
Query Neighborhood Hits	472	Target Neighborhood Hits	354	Shared Neighborhood Hits	61
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PRB3_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.054576 (rank : 407)
Query Neighborhood Hits	472	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRB4S_HUMAN
θ value	θ > 10 (rank : 611)	NC score	0.064423 (rank : 323)
Query Neighborhood Hits	472	Target Neighborhood Hits	330	Shared Neighborhood Hits	62
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRG4_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.105960 (rank : 168)
Query Neighborhood Hits	472	Target Neighborhood Hits	764	Shared Neighborhood Hits	117
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRG4_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.077949 (rank : 246)
Query Neighborhood Hits	472	Target Neighborhood Hits	624	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP1_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.085840 (rank : 215)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	70
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.089996 (rank : 201)
Query Neighborhood Hits	472	Target Neighborhood Hits	347	Shared Neighborhood Hits	58
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRRT3_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.077661 (rank : 250)
Query Neighborhood Hits	472	Target Neighborhood Hits	998	Shared Neighborhood Hits	125
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PSL1_HUMAN
θ value	θ > 10 (rank : 617)	NC score	0.055980 (rank : 391)
Query Neighborhood Hits	472	Target Neighborhood Hits	650	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RA54B_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.059131 (rank : 364)
Query Neighborhood Hits	472	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.058771 (rank : 368)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.060934 (rank : 346)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.060184 (rank : 353)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RAPH1_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.074130 (rank : 274)
Query Neighborhood Hits	472	Target Neighborhood Hits	593	Shared Neighborhood Hits	99
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RBBP6_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.093566 (rank : 194)
Query Neighborhood Hits	472	Target Neighborhood Hits	1135	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.090074 (rank : 200)
Query Neighborhood Hits	472	Target Neighborhood Hits	1014	Shared Neighborhood Hits	123
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RERE_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.067136 (rank : 308)
Query Neighborhood Hits	472	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.070280 (rank : 292)
Query Neighborhood Hits	472	Target Neighborhood Hits	785	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RP1L1_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.050108 (rank : 450)
Query Neighborhood Hits	472	Target Neighborhood Hits	1072	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RPB1_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.055415 (rank : 397)
Query Neighborhood Hits	472	Target Neighborhood Hits	362	Shared Neighborhood Hits	62
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.055564 (rank : 395)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	61
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RTP3_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.071205 (rank : 285)
Query Neighborhood Hits	472	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RUSC2_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.050456 (rank : 446)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SELPL_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.114066 (rank : 153)
Query Neighborhood Hits	472	Target Neighborhood Hits	588	Shared Neighborhood Hits	116
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SETBP_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.051022 (rank : 436)
Query Neighborhood Hits	472	Target Neighborhood Hits	352	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETD7_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.059828 (rank : 357)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.060115 (rank : 354)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SFR15_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.055093 (rank : 399)
Query Neighborhood Hits	472	Target Neighborhood Hits	368	Shared Neighborhood Hits	55
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SFRIP_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.078814 (rank : 244)
Query Neighborhood Hits	472	Target Neighborhood Hits	530	Shared Neighborhood Hits	104
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SFRS8_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.055783 (rank : 393)
Query Neighborhood Hits	472	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SGIP1_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.051240 (rank : 432)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SHAN1_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.054313 (rank : 411)
Query Neighborhood Hits	472	Target Neighborhood Hits	1041	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SMAL1_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.062616 (rank : 336)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	θ > 10 (rank : 642)	NC score	0.060411 (rank : 351)
Query Neighborhood Hits	472	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SMCA1_HUMAN
θ value	θ > 10 (rank : 643)	NC score	0.064297 (rank : 324)
Query Neighborhood Hits	472	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 644)	NC score	0.064220 (rank : 325)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.095151 (rank : 192)
Query Neighborhood Hits	472	Target Neighborhood Hits	503	Shared Neighborhood Hits	85
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.098480 (rank : 180)
Query Neighborhood Hits	472	Target Neighborhood Hits	597	Shared Neighborhood Hits	96
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA5_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.062618 (rank : 335)
Query Neighborhood Hits	472	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 648)	NC score	0.062674 (rank : 334)
Query Neighborhood Hits	472	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRCD_HUMAN
θ value	θ > 10 (rank : 649)	NC score	0.059529 (rank : 360)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 650)	NC score	0.058547 (rank : 370)
Query Neighborhood Hits	472	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SNPC4_HUMAN
θ value	θ > 10 (rank : 651)	NC score	0.050992 (rank : 438)
Query Neighborhood Hits	472	Target Neighborhood Hits	589	Shared Neighborhood Hits	90
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SRCH_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.063824 (rank : 327)
Query Neighborhood Hits	472	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

SYNJ1_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.053636 (rank : 414)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	96
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYNJ1_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.050911 (rank : 439)
Query Neighborhood Hits	472	Target Neighborhood Hits	516	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

T22D2_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.054620 (rank : 406)
Query Neighborhood Hits	472	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

T2FA_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.058748 (rank : 369)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	42
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TAF1L_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.072892 (rank : 280)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.075409 (rank : 265)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TAF3_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.149033 (rank : 109)
Query Neighborhood Hits	472	Target Neighborhood Hits	568	Shared Neighborhood Hits	127
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.140181 (rank : 113)
Query Neighborhood Hits	472	Target Neighborhood Hits	463	Shared Neighborhood Hits	113
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF4_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.074042 (rank : 275)
Query Neighborhood Hits	472	Target Neighborhood Hits	687	Shared Neighborhood Hits	92
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAU_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.066493 (rank : 311)
Query Neighborhood Hits	472	Target Neighborhood Hits	502	Shared Neighborhood Hits	89
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCAL5_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.073546 (rank : 277)
Query Neighborhood Hits	472	Target Neighborhood Hits	806	Shared Neighborhood Hits	97
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TCOF_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.081933 (rank : 234)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	101
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TCOF_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.088640 (rank : 208)
Query Neighborhood Hits	472	Target Neighborhood Hits	471	Shared Neighborhood Hits	87
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TGON2_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.126900 (rank : 127)
Query Neighborhood Hits	472	Target Neighborhood Hits	1037	Shared Neighborhood Hits	170
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIP60_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.066068 (rank : 315)
Query Neighborhood Hits	472	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.066116 (rank : 314)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TM108_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.066310 (rank : 313)
Query Neighborhood Hits	472	Target Neighborhood Hits	336	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TP53B_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.089881 (rank : 202)
Query Neighborhood Hits	472	Target Neighborhood Hits	644	Shared Neighborhood Hits	111
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TRI45_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.071385 (rank : 284)
Query Neighborhood Hits	472	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.070912 (rank : 288)
Query Neighborhood Hits	472	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI56_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.054327 (rank : 410)
Query Neighborhood Hits	472	Target Neighborhood Hits	339	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.050533 (rank : 445)
Query Neighborhood Hits	472	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TXND2_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.091483 (rank : 197)
Query Neighborhood Hits	472	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

WASIP_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.084249 (rank : 222)
Query Neighborhood Hits	472	Target Neighborhood Hits	458	Shared Neighborhood Hits	78
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.085069 (rank : 218)
Query Neighborhood Hits	472	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WBP11_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.050114 (rank : 449)
Query Neighborhood Hits	472	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WIRE_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.068640 (rank : 300)
Query Neighborhood Hits	472	Target Neighborhood Hits	329	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

WIRE_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.057915 (rank : 373)
Query Neighborhood Hits	472	Target Neighborhood Hits	310	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

YLPM1_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.077261 (rank : 253)
Query Neighborhood Hits	472	Target Neighborhood Hits	670	Shared Neighborhood Hits	95
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

YLPM1_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.070600 (rank : 291)
Query Neighborhood Hits	472	Target Neighborhood Hits	505	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ZCPW1_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.074296 (rank : 273)
Query Neighborhood Hits	472	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

ZN207_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.052014 (rank : 424)
Query Neighborhood Hits	472	Target Neighborhood Hits	326	Shared Neighborhood Hits	41
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

Hits sorted by NC score

NSD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	472	Target Neighborhood Hits	472	Shared Neighborhood Hits	472
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.945555 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	236
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SETD2_HUMAN
NC score	0.641356 (rank : 3)	θ value	2.18568e-46 (rank : 3)
Query Neighborhood Hits	472	Target Neighborhood Hits	412	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SUV92_HUMAN
NC score	0.589334 (rank : 4)	θ value	8.93572e-24 (rank : 4)
Query Neighborhood Hits	472	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.581610 (rank : 5)	θ value	2.20094e-22 (rank : 5)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_HUMAN
NC score	0.574718 (rank : 6)	θ value	6.62687e-19 (rank : 10)
Query Neighborhood Hits	472	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
NC score	0.567804 (rank : 7)	θ value	1.47631e-18 (rank : 12)
Query Neighborhood Hits	472	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

EZH2_HUMAN
NC score	0.565590 (rank : 8)	θ value	2.06002e-20 (rank : 6)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.563270 (rank : 9)	θ value	4.58923e-20 (rank : 7)
Query Neighborhood Hits	472	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_MOUSE
NC score	0.562526 (rank : 10)	θ value	1.33526e-19 (rank : 9)
Query Neighborhood Hits	472	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_HUMAN
NC score	0.561693 (rank : 11)	θ value	1.33526e-19 (rank : 8)
Query Neighborhood Hits	472	Target Neighborhood Hits	121	Shared Neighborhood Hits	39
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

HRX_HUMAN
NC score	0.552672 (rank : 12)	θ value	1.47631e-18 (rank : 11)
Query Neighborhood Hits	472	Target Neighborhood Hits	825	Shared Neighborhood Hits	191
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
NC score	0.542590 (rank : 13)	θ value	3.07829e-16 (rank : 13)
Query Neighborhood Hits	472	Target Neighborhood Hits	722	Shared Neighborhood Hits	176
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SET1A_HUMAN
NC score	0.530480 (rank : 14)	θ value	4.02038e-16 (rank : 15)
Query Neighborhood Hits	472	Target Neighborhood Hits	690	Shared Neighborhood Hits	126
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MLL2_HUMAN
NC score	0.499758 (rank : 15)	θ value	1.86753e-13 (rank : 18)
Query Neighborhood Hits	472	Target Neighborhood Hits	1788	Shared Neighborhood Hits	255
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
NC score	0.490926 (rank : 16)	θ value	1.2105e-12 (rank : 20)
Query Neighborhood Hits	472	Target Neighborhood Hits	1399	Shared Neighborhood Hits	237
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.473040 (rank : 17)	θ value	9.26847e-13 (rank : 19)
Query Neighborhood Hits	472	Target Neighborhood Hits	1644	Shared Neighborhood Hits	245
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETD8_MOUSE
NC score	0.466594 (rank : 18)	θ value	1.29631e-06 (rank : 38)
Query Neighborhood Hits	472	Target Neighborhood Hits	131	Shared Neighborhood Hits	54
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.465416 (rank : 19)	θ value	9.92553e-07 (rank : 37)
Query Neighborhood Hits	472	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

AIRE_HUMAN
NC score	0.449509 (rank : 20)	θ value	3.08544e-08 (rank : 31)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	88
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.441962 (rank : 21)	θ value	4.0297e-08 (rank : 34)
Query Neighborhood Hits	472	Target Neighborhood Hits	196	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

SETB2_HUMAN
NC score	0.434321 (rank : 22)	θ value	1.43324e-05 (rank : 42)
Query Neighborhood Hits	472	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.427981 (rank : 23)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	472	Target Neighborhood Hits	150	Shared Neighborhood Hits	46
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.424029 (rank : 24)	θ value	3.08544e-08 (rank : 32)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	42
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

PHF12_HUMAN
NC score	0.407460 (rank : 25)	θ value	4.76016e-09 (rank : 25)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.403406 (rank : 26)	θ value	1.80886e-08 (rank : 28)
Query Neighborhood Hits	472	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21A_MOUSE
NC score	0.387518 (rank : 27)	θ value	2.44474e-05 (rank : 44)
Query Neighborhood Hits	472	Target Neighborhood Hits	285	Shared Neighborhood Hits	103
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.384196 (rank : 28)	θ value	7.1131e-05 (rank : 50)
Query Neighborhood Hits	472	Target Neighborhood Hits	303	Shared Neighborhood Hits	109
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PKCB1_HUMAN
NC score	0.372804 (rank : 29)	θ value	2.61198e-07 (rank : 35)
Query Neighborhood Hits	472	Target Neighborhood Hits	488	Shared Neighborhood Hits	153
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_HUMAN
NC score	0.363952 (rank : 30)	θ value	5.44631e-05 (rank : 47)
Query Neighborhood Hits	472	Target Neighborhood Hits	197	Shared Neighborhood Hits	91
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
NC score	0.351869 (rank : 31)	θ value	0.000461057 (rank : 59)
Query Neighborhood Hits	472	Target Neighborhood Hits	278	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

TRI66_MOUSE
NC score	0.345014 (rank : 32)	θ value	1.29631e-06 (rank : 39)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	116
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_HUMAN
NC score	0.342943 (rank : 33)	θ value	5.81887e-07 (rank : 36)
Query Neighborhood Hits	472	Target Neighborhood Hits	479	Shared Neighborhood Hits	114
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_MOUSE
NC score	0.340931 (rank : 34)	θ value	1.06045e-08 (rank : 27)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	107
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.334283 (rank : 35)	θ value	8.11959e-09 (rank : 26)
Query Neighborhood Hits	472	Target Neighborhood Hits	327	Shared Neighborhood Hits	98
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1G_MOUSE
NC score	0.319911 (rank : 36)	θ value	2.36244e-08 (rank : 30)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	122
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.316159 (rank : 37)	θ value	1.80886e-08 (rank : 29)
Query Neighborhood Hits	472	Target Neighborhood Hits	410	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

BPTF_HUMAN
NC score	0.312493 (rank : 38)	θ value	2.88788e-06 (rank : 41)
Query Neighborhood Hits	472	Target Neighborhood Hits	786	Shared Neighborhood Hits	158
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

LY10_HUMAN
NC score	0.302665 (rank : 39)	θ value	0.000158464 (rank : 54)
Query Neighborhood Hits	472	Target Neighborhood Hits	151	Shared Neighborhood Hits	73
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

RSF1_HUMAN
NC score	0.295607 (rank : 40)	θ value	0.0193708 (rank : 102)
Query Neighborhood Hits	472	Target Neighborhood Hits	539	Shared Neighborhood Hits	127
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PHF10_HUMAN
NC score	0.295306 (rank : 41)	θ value	0.125558 (rank : 137)
Query Neighborhood Hits	472	Target Neighborhood Hits	151	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

EHMT2_MOUSE
NC score	0.293570 (rank : 42)	θ value	6.85773e-16 (rank : 17)
Query Neighborhood Hits	472	Target Neighborhood Hits	750	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

SP110_HUMAN
NC score	0.291635 (rank : 43)	θ value	0.000270298 (rank : 57)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

PHF10_MOUSE
NC score	0.288271 (rank : 44)	θ value	0.279714 (rank : 163)
Query Neighborhood Hits	472	Target Neighborhood Hits	131	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

EHMT2_HUMAN
NC score	0.287083 (rank : 45)	θ value	5.25075e-16 (rank : 16)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TIF1B_HUMAN
NC score	0.283706 (rank : 46)	θ value	7.1131e-05 (rank : 51)
Query Neighborhood Hits	472	Target Neighborhood Hits	312	Shared Neighborhood Hits	77
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

EHMT1_HUMAN
NC score	0.282136 (rank : 47)	θ value	4.02038e-16 (rank : 14)
Query Neighborhood Hits	472	Target Neighborhood Hits	417	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

TIF1B_MOUSE
NC score	0.280900 (rank : 48)	θ value	0.000602161 (rank : 61)
Query Neighborhood Hits	472	Target Neighborhood Hits	276	Shared Neighborhood Hits	76
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

CHD5_HUMAN
NC score	0.279938 (rank : 49)	θ value	4.59992e-12 (rank : 21)
Query Neighborhood Hits	472	Target Neighborhood Hits	349	Shared Neighborhood Hits	106
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

BAZ1B_MOUSE
NC score	0.279809 (rank : 50)	θ value	0.00869519 (rank : 92)
Query Neighborhood Hits	472	Target Neighborhood Hits	394	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MYST4_HUMAN
NC score	0.279435 (rank : 51)	θ value	2.44474e-05 (rank : 43)
Query Neighborhood Hits	472	Target Neighborhood Hits	671	Shared Neighborhood Hits	144
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DPF1_HUMAN
NC score	0.279068 (rank : 52)	θ value	0.0330416 (rank : 108)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	74
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST3_MOUSE
NC score	0.277740 (rank : 53)	θ value	7.1131e-05 (rank : 48)
Query Neighborhood Hits	472	Target Neighborhood Hits	688	Shared Neighborhood Hits	164
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_MOUSE
NC score	0.276910 (rank : 54)	θ value	4.1701e-05 (rank : 45)
Query Neighborhood Hits	472	Target Neighborhood Hits	416	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

MYST3_HUMAN
NC score	0.274782 (rank : 55)	θ value	9.29e-05 (rank : 52)
Query Neighborhood Hits	472	Target Neighborhood Hits	772	Shared Neighborhood Hits	165
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

BAZ2A_HUMAN
NC score	0.272607 (rank : 56)	θ value	0.0148317 (rank : 96)
Query Neighborhood Hits	472	Target Neighborhood Hits	780	Shared Neighborhood Hits	156
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ1A_HUMAN
NC score	0.270406 (rank : 57)	θ value	0.0431538 (rank : 113)
Query Neighborhood Hits	472	Target Neighborhood Hits	693	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CHD4_MOUSE
NC score	0.270364 (rank : 58)	θ value	4.76016e-09 (rank : 24)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
NC score	0.269678 (rank : 59)	θ value	2.79066e-09 (rank : 22)
Query Neighborhood Hits	472	Target Neighborhood Hits	397	Shared Neighborhood Hits	125
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.268891 (rank : 60)	θ value	4.76016e-09 (rank : 23)
Query Neighborhood Hits	472	Target Neighborhood Hits	365	Shared Neighborhood Hits	113
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

BAZ2A_MOUSE
NC score	0.268808 (rank : 61)	θ value	0.0431538 (rank : 114)
Query Neighborhood Hits	472	Target Neighborhood Hits	744	Shared Neighborhood Hits	161
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ1B_HUMAN
NC score	0.268410 (rank : 62)	θ value	0.00869519 (rank : 91)
Query Neighborhood Hits	472	Target Neighborhood Hits	701	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DPF1_MOUSE
NC score	0.258195 (rank : 63)	θ value	0.0961366 (rank : 132)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.258035 (rank : 64)	θ value	0.0736092 (rank : 129)
Query Neighborhood Hits	472	Target Neighborhood Hits	523	Shared Neighborhood Hits	84
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.256181 (rank : 65)	θ value	0.0736092 (rank : 130)
Query Neighborhood Hits	472	Target Neighborhood Hits	519	Shared Neighborhood Hits	82
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BRPF1_HUMAN
NC score	0.255825 (rank : 66)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	472	Target Neighborhood Hits	259	Shared Neighborhood Hits	109
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

ZMY11_MOUSE
NC score	0.252918 (rank : 67)	θ value	0.00509761 (rank : 90)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

JADE2_MOUSE
NC score	0.246160 (rank : 68)	θ value	0.00228821 (rank : 78)
Query Neighborhood Hits	472	Target Neighborhood Hits	560	Shared Neighborhood Hits	148
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_HUMAN
NC score	0.244301 (rank : 69)	θ value	0.00390308 (rank : 88)
Query Neighborhood Hits	472	Target Neighborhood Hits	199	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_MOUSE
NC score	0.243641 (rank : 70)	θ value	0.00102713 (rank : 66)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	90
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

BRD1_HUMAN
NC score	0.242510 (rank : 71)	θ value	0.00228821 (rank : 77)
Query Neighborhood Hits	472	Target Neighborhood Hits	188	Shared Neighborhood Hits	86
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

JADE1_HUMAN
NC score	0.242257 (rank : 72)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	472	Target Neighborhood Hits	140	Shared Neighborhood Hits	84
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

BAZ2B_HUMAN
NC score	0.242072 (rank : 73)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	472	Target Neighborhood Hits	803	Shared Neighborhood Hits	132
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

JADE1_MOUSE
NC score	0.241606 (rank : 74)	θ value	0.00134147 (rank : 72)
Query Neighborhood Hits	472	Target Neighborhood Hits	160	Shared Neighborhood Hits	85
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
NC score	0.241278 (rank : 75)	θ value	0.00134147 (rank : 73)
Query Neighborhood Hits	472	Target Neighborhood Hits	148	Shared Neighborhood Hits	90
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

BRPF3_HUMAN
NC score	0.240959 (rank : 76)	θ value	0.00869519 (rank : 93)
Query Neighborhood Hits	472	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

JAD1A_HUMAN
NC score	0.240027 (rank : 77)	θ value	0.00134147 (rank : 70)
Query Neighborhood Hits	472	Target Neighborhood Hits	328	Shared Neighborhood Hits	99
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

ZMY11_HUMAN
NC score	0.237537 (rank : 78)	θ value	0.0563607 (rank : 125)
Query Neighborhood Hits	472	Target Neighborhood Hits	201	Shared Neighborhood Hits	81
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PHF14_MOUSE
NC score	0.237237 (rank : 79)	θ value	3.0926 (rank : 304)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	112
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.232833 (rank : 80)	θ value	3.0926 (rank : 303)
Query Neighborhood Hits	472	Target Neighborhood Hits	447	Shared Neighborhood Hits	110
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

ING5_HUMAN
NC score	0.230089 (rank : 81)	θ value	0.00134147 (rank : 68)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
NC score	0.227283 (rank : 82)	θ value	0.00134147 (rank : 69)
Query Neighborhood Hits	472	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

JAD1C_MOUSE
NC score	0.223780 (rank : 83)	θ value	0.00175202 (rank : 76)
Query Neighborhood Hits	472	Target Neighborhood Hits	164	Shared Neighborhood Hits	82
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
NC score	0.223564 (rank : 84)	θ value	0.0330416 (rank : 109)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_HUMAN
NC score	0.223211 (rank : 85)	θ value	0.00175202 (rank : 75)
Query Neighborhood Hits	472	Target Neighborhood Hits	187	Shared Neighborhood Hits	83
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

UHRF1_MOUSE
NC score	0.219894 (rank : 86)	θ value	0.0736092 (rank : 131)
Query Neighborhood Hits	472	Target Neighborhood Hits	278	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF1_HUMAN
NC score	0.216509 (rank : 87)	θ value	0.365318 (rank : 184)
Query Neighborhood Hits	472	Target Neighborhood Hits	272	Shared Neighborhood Hits	75
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ING2_HUMAN
NC score	0.216087 (rank : 88)	θ value	0.00035302 (rank : 58)
Query Neighborhood Hits	472	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
NC score	0.215852 (rank : 89)	θ value	0.000786445 (rank : 62)
Query Neighborhood Hits	472	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING3_HUMAN
NC score	0.212913 (rank : 90)	θ value	0.00102713 (rank : 64)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING3_MOUSE
NC score	0.210910 (rank : 91)	θ value	0.00102713 (rank : 65)
Query Neighborhood Hits	472	Target Neighborhood Hits	177	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

JAD1D_MOUSE
NC score	0.208108 (rank : 92)	θ value	0.47712 (rank : 189)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	83
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

AF17_HUMAN
NC score	0.206226 (rank : 93)	θ value	0.0113563 (rank : 94)
Query Neighborhood Hits	472	Target Neighborhood Hits	230	Shared Neighborhood Hits	96
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

UHRF2_HUMAN
NC score	0.203290 (rank : 94)	θ value	0.0961366 (rank : 133)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	75
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ING1_HUMAN
NC score	0.202471 (rank : 95)	θ value	0.00298849 (rank : 83)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
NC score	0.202329 (rank : 96)	θ value	0.00298849 (rank : 84)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING4_HUMAN
NC score	0.197066 (rank : 97)	θ value	0.0148317 (rank : 98)
Query Neighborhood Hits	472	Target Neighborhood Hits	82	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
NC score	0.196004 (rank : 98)	θ value	0.0148317 (rank : 99)
Query Neighborhood Hits	472	Target Neighborhood Hits	93	Shared Neighborhood Hits	47
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

AF10_MOUSE
NC score	0.193145 (rank : 99)	θ value	0.00298849 (rank : 81)
Query Neighborhood Hits	472	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

UHRF2_MOUSE
NC score	0.192269 (rank : 100)	θ value	1.38821 (rank : 247)
Query Neighborhood Hits	472	Target Neighborhood Hits	275	Shared Neighborhood Hits	77
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

AF10_HUMAN
NC score	0.191302 (rank : 101)	θ value	0.00298849 (rank : 80)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

PHF7_HUMAN
NC score	0.189314 (rank : 102)	θ value	0.000461057 (rank : 60)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SRRM1_MOUSE
NC score	0.171136 (rank : 103)	θ value	0.0193708 (rank : 103)
Query Neighborhood Hits	472	Target Neighborhood Hits	966	Shared Neighborhood Hits	159
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
NC score	0.170604 (rank : 104)	θ value	0.00390308 (rank : 89)
Query Neighborhood Hits	472	Target Neighborhood Hits	690	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

PHF7_MOUSE
NC score	0.169005 (rank : 105)	θ value	0.0252991 (rank : 107)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	41
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

NACAM_MOUSE
NC score	0.166950 (rank : 106)	θ value	5.44631e-05 (rank : 46)
Query Neighborhood Hits	472	Target Neighborhood Hits	1866	Shared Neighborhood Hits	213
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ATRX_MOUSE
NC score	0.151857 (rank : 107)	θ value	0.00298849 (rank : 82)
Query Neighborhood Hits	472	Target Neighborhood Hits	682	Shared Neighborhood Hits	101
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

TXND2_HUMAN
NC score	0.151583 (rank : 108)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	472	Target Neighborhood Hits	793	Shared Neighborhood Hits	148
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TAF3_HUMAN
NC score	0.149033 (rank : 109)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	472	Target Neighborhood Hits	568	Shared Neighborhood Hits	127
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

RAI1_MOUSE
NC score	0.147537 (rank : 110)	θ value	0.813845 (rank : 211)
Query Neighborhood Hits	472	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

MDC1_HUMAN
NC score	0.146235 (rank : 111)	θ value	1.81305 (rank : 259)
Query Neighborhood Hits	472	Target Neighborhood Hits	1446	Shared Neighborhood Hits	194
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ATRX_HUMAN
NC score	0.143185 (rank : 112)	θ value	0.00390308 (rank : 87)
Query Neighborhood Hits	472	Target Neighborhood Hits	842	Shared Neighborhood Hits	116
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TAF3_MOUSE
NC score	0.140181 (rank : 113)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	472	Target Neighborhood Hits	463	Shared Neighborhood Hits	113
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SRRM2_HUMAN
NC score	0.139189 (rank : 114)	θ value	0.0563607 (rank : 122)
Query Neighborhood Hits	472	Target Neighborhood Hits	1296	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

LAD1_HUMAN
NC score	0.137289 (rank : 115)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	472	Target Neighborhood Hits	441	Shared Neighborhood Hits	93
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

MDC1_MOUSE
NC score	0.136246 (rank : 116)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	472	Target Neighborhood Hits	998	Shared Neighborhood Hits	167
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PP1RA_HUMAN
NC score	0.136149 (rank : 117)	θ value	2.21117e-06 (rank : 40)
Query Neighborhood Hits	472	Target Neighborhood Hits	180	Shared Neighborhood Hits	29
SwissProt Accessions	Q96QC0, O00405	Gene names	PPP1R10, CAT53, FB19, PNUTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (Phosphatase 1 nuclear targeting subunit) (MHC class I region proline- rich protein CAT53) (FB19 protein) (PP1-binding protein of 114 kDa) (p99).

TCF20_MOUSE
NC score	0.135596 (rank : 118)	θ value	0.47712 (rank : 194)
Query Neighborhood Hits	472	Target Neighborhood Hits	396	Shared Neighborhood Hits	91
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

RAI1_HUMAN
NC score	0.133142 (rank : 119)	θ value	2.36792 (rank : 278)
Query Neighborhood Hits	472	Target Neighborhood Hits	360	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SRRM2_MOUSE
NC score	0.133110 (rank : 120)	θ value	0.0193708 (rank : 104)
Query Neighborhood Hits	472	Target Neighborhood Hits	1470	Shared Neighborhood Hits	185
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SON_HUMAN
NC score	0.130725 (rank : 121)	θ value	0.0431538 (rank : 117)
Query Neighborhood Hits	472	Target Neighborhood Hits	1568	Shared Neighborhood Hits	186
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NCOA6_HUMAN
NC score	0.130724 (rank : 122)	θ value	0.0113563 (rank : 95)
Query Neighborhood Hits	472	Target Neighborhood Hits	1202	Shared Neighborhood Hits	150
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NIPBL_HUMAN
NC score	0.129515 (rank : 123)	θ value	0.365318 (rank : 177)
Query Neighborhood Hits	472	Target Neighborhood Hits	1311	Shared Neighborhood Hits	157
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MTF2_MOUSE
NC score	0.128801 (rank : 124)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	472	Target Neighborhood Hits	126	Shared Neighborhood Hits	73
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_HUMAN
NC score	0.128232 (rank : 125)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	472	Target Neighborhood Hits	119	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

NPBL_MOUSE
NC score	0.127978 (rank : 126)	θ value	0.279714 (rank : 162)
Query Neighborhood Hits	472	Target Neighborhood Hits	1041	Shared Neighborhood Hits	150
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TGON2_HUMAN
NC score	0.126900 (rank : 127)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	472	Target Neighborhood Hits	1037	Shared Neighborhood Hits	170
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

PCLO_HUMAN
NC score	0.126267 (rank : 128)	θ value	0.125558 (rank : 136)
Query Neighborhood Hits	472	Target Neighborhood Hits	2046	Shared Neighborhood Hits	215
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PP1RA_MOUSE
NC score	0.125896 (rank : 129)	θ value	0.000121331 (rank : 53)
Query Neighborhood Hits	472	Target Neighborhood Hits	175	Shared Neighborhood Hits	30
SwissProt Accessions	Q80W00, Q811B6, Q8C6T7, Q8K2U8	Gene names	Ppp1r10, Cat53
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53).

BRD4_MOUSE
NC score	0.125774 (rank : 130)	θ value	2.36792 (rank : 266)
Query Neighborhood Hits	472	Target Neighborhood Hits	845	Shared Neighborhood Hits	117
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CBP_MOUSE
NC score	0.125215 (rank : 131)	θ value	0.163984 (rank : 140)
Query Neighborhood Hits	472	Target Neighborhood Hits	1051	Shared Neighborhood Hits	157
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TCF20_HUMAN
NC score	0.124302 (rank : 132)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	472	Target Neighborhood Hits	323	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

IWS1_MOUSE
NC score	0.124212 (rank : 133)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	472	Target Neighborhood Hits	1258	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PHF11_HUMAN
NC score	0.123611 (rank : 134)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

JHD3C_HUMAN
NC score	0.122656 (rank : 135)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	472	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

ELOA1_HUMAN
NC score	0.122611 (rank : 136)	θ value	0.0148317 (rank : 97)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	72
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

PHF6_HUMAN
NC score	0.122181 (rank : 137)	θ value	6.88961 (rank : 404)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

BRD4_HUMAN
NC score	0.121256 (rank : 138)	θ value	1.38821 (rank : 232)
Query Neighborhood Hits	472	Target Neighborhood Hits	851	Shared Neighborhood Hits	125
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TARA_HUMAN
NC score	0.120916 (rank : 139)	θ value	0.0563607 (rank : 123)
Query Neighborhood Hits	472	Target Neighborhood Hits	1626	Shared Neighborhood Hits	189
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PHF1_HUMAN
NC score	0.120549 (rank : 140)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.119777 (rank : 141)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	472	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

TARSH_HUMAN
NC score	0.119388 (rank : 142)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	472	Target Neighborhood Hits	768	Shared Neighborhood Hits	120
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

DSPP_HUMAN
NC score	0.119005 (rank : 143)	θ value	0.00020696 (rank : 56)
Query Neighborhood Hits	472	Target Neighborhood Hits	645	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PHF6_MOUSE
NC score	0.118254 (rank : 144)	θ value	6.88961 (rank : 405)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

NCOA6_MOUSE
NC score	0.117828 (rank : 145)	θ value	0.365318 (rank : 176)
Query Neighborhood Hits	472	Target Neighborhood Hits	1076	Shared Neighborhood Hits	133
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

LAD1_MOUSE
NC score	0.117777 (rank : 146)	θ value	3.0926 (rank : 297)
Query Neighborhood Hits	472	Target Neighborhood Hits	391	Shared Neighborhood Hits	89
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

EP300_HUMAN
NC score	0.116585 (rank : 147)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	472	Target Neighborhood Hits	821	Shared Neighborhood Hits	122
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CXCC1_HUMAN
NC score	0.115780 (rank : 148)	θ value	5.27518 (rank : 347)
Query Neighborhood Hits	472	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

IWS1_HUMAN
NC score	0.115359 (rank : 149)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	472	Target Neighborhood Hits	1241	Shared Neighborhood Hits	167
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZCPW1_MOUSE
NC score	0.115195 (rank : 150)	θ value	1.06291 (rank : 229)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	63
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

CBP_HUMAN
NC score	0.114753 (rank : 151)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	472	Target Neighborhood Hits	941	Shared Neighborhood Hits	144
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NFH_MOUSE
NC score	0.114649 (rank : 152)	θ value	0.0193708 (rank : 101)
Query Neighborhood Hits	472	Target Neighborhood Hits	2247	Shared Neighborhood Hits	256
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SELPL_MOUSE
NC score	0.114066 (rank : 153)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	472	Target Neighborhood Hits	588	Shared Neighborhood Hits	116
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CXCC1_MOUSE
NC score	0.113586 (rank : 154)	θ value	5.27518 (rank : 348)
Query Neighborhood Hits	472	Target Neighborhood Hits	124	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

SON_MOUSE
NC score	0.113249 (rank : 155)	θ value	0.279714 (rank : 165)
Query Neighborhood Hits	472	Target Neighborhood Hits	957	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BRD8_MOUSE
NC score	0.112205 (rank : 156)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	472	Target Neighborhood Hits	422	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

PCLO_MOUSE
NC score	0.111204 (rank : 157)	θ value	0.0736092 (rank : 128)
Query Neighborhood Hits	472	Target Neighborhood Hits	2275	Shared Neighborhood Hits	221
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

JHD3C_MOUSE
NC score	0.110919 (rank : 158)	θ value	6.88961 (rank : 396)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

PHF20_MOUSE
NC score	0.110814 (rank : 159)	θ value	0.365318 (rank : 178)
Query Neighborhood Hits	472	Target Neighborhood Hits	513	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

NOLC1_HUMAN
NC score	0.110690 (rank : 160)	θ value	2.36792 (rank : 276)
Query Neighborhood Hits	472	Target Neighborhood Hits	452	Shared Neighborhood Hits	95
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CS016_HUMAN
NC score	0.110455 (rank : 161)	θ value	0.62314 (rank : 195)
Query Neighborhood Hits	472	Target Neighborhood Hits	310	Shared Neighborhood Hits	70
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

K1802_MOUSE
NC score	0.109077 (rank : 162)	θ value	0.00228821 (rank : 79)
Query Neighborhood Hits	472	Target Neighborhood Hits	1596	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

JHD3B_MOUSE
NC score	0.109054 (rank : 163)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	472	Target Neighborhood Hits	152	Shared Neighborhood Hits	53
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

CECR2_HUMAN
NC score	0.108610 (rank : 164)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

RGS3_MOUSE
NC score	0.107783 (rank : 165)	θ value	0.0330416 (rank : 111)
Query Neighborhood Hits	472	Target Neighborhood Hits	1621	Shared Neighborhood Hits	189
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

JHD3A_MOUSE
NC score	0.106791 (rank : 166)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

INGX_HUMAN
NC score	0.106597 (rank : 167)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	472	Target Neighborhood Hits	13	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

PRG4_HUMAN
NC score	0.105960 (rank : 168)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	472	Target Neighborhood Hits	764	Shared Neighborhood Hits	117
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

K1333_MOUSE
NC score	0.105395 (rank : 169)	θ value	8.99809 (rank : 441)
Query Neighborhood Hits	472	Target Neighborhood Hits	53	Shared Neighborhood Hits	30
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

MAP1B_HUMAN
NC score	0.105200 (rank : 170)	θ value	0.0193708 (rank : 100)
Query Neighborhood Hits	472	Target Neighborhood Hits	903	Shared Neighborhood Hits	118
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

PWWP2_HUMAN
NC score	0.104737 (rank : 171)	θ value	0.47712 (rank : 192)
Query Neighborhood Hits	472	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NUJ5, Q5SZI0, Q6ZQX5, Q96F43	Gene names	PWWP2
Domain Architecture	No domain graphic available
Description	PWWP domain-containing protein 2.

JHD3A_HUMAN
NC score	0.104398 (rank : 172)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	472	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
NC score	0.104228 (rank : 173)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	472	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

MAP1A_HUMAN
NC score	0.102990 (rank : 174)	θ value	0.21417 (rank : 154)
Query Neighborhood Hits	472	Target Neighborhood Hits	1626	Shared Neighborhood Hits	172
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

GSCR1_HUMAN
NC score	0.100992 (rank : 175)	θ value	8.99809 (rank : 435)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	113
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

KI67_HUMAN
NC score	0.099965 (rank : 176)	θ value	1.81305 (rank : 257)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	92
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

HDGF_MOUSE
NC score	0.099473 (rank : 177)	θ value	0.365318 (rank : 174)
Query Neighborhood Hits	472	Target Neighborhood Hits	102	Shared Neighborhood Hits	27
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

PSIP1_HUMAN
NC score	0.099244 (rank : 178)	θ value	0.365318 (rank : 179)
Query Neighborhood Hits	472	Target Neighborhood Hits	341	Shared Neighborhood Hits	57
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
NC score	0.099157 (rank : 179)	θ value	0.365318 (rank : 180)
Query Neighborhood Hits	472	Target Neighborhood Hits	313	Shared Neighborhood Hits	52
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

SMCA4_HUMAN
NC score	0.098480 (rank : 180)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	472	Target Neighborhood Hits	597	Shared Neighborhood Hits	96
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

DIDO1_HUMAN
NC score	0.098401 (rank : 181)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	472	Target Neighborhood Hits	960	Shared Neighborhood Hits	165
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PHF22_MOUSE
NC score	0.097365 (rank : 182)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	472	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

BSN_MOUSE
NC score	0.097030 (rank : 183)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	472	Target Neighborhood Hits	2057	Shared Neighborhood Hits	195
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

HDGR3_MOUSE
NC score	0.096996 (rank : 184)	θ value	0.21417 (rank : 153)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JMG7, Q3TRX2, Q8BQ69, Q8BR62, Q9D2M7	Gene names	Hdgfrp3
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3).

MUC7_HUMAN
NC score	0.096904 (rank : 185)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	472	Target Neighborhood Hits	538	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

HDGR3_HUMAN
NC score	0.096717 (rank : 186)	θ value	0.21417 (rank : 152)
Query Neighborhood Hits	472	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3E1	Gene names	HDGFRP3, HDGF2
Domain Architecture	No domain graphic available
Description	Hepatoma-derived growth factor-related protein 3 (HRP-3) (Hepatoma- derived growth factor 2).

PHF20_HUMAN
NC score	0.096701 (rank : 187)	θ value	2.36792 (rank : 277)
Query Neighborhood Hits	472	Target Neighborhood Hits	394	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

HDGF_HUMAN
NC score	0.096213 (rank : 188)	θ value	0.365318 (rank : 173)
Query Neighborhood Hits	472	Target Neighborhood Hits	61	Shared Neighborhood Hits	22
SwissProt Accessions	P51858, Q5SZ09	Gene names	HDGF, HMG1L2
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF) (High-mobility group protein 1- like 2) (HMG-1L2).

BRD8_HUMAN
NC score	0.095646 (rank : 189)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	472	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

LCP2_HUMAN
NC score	0.095439 (rank : 190)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	472	Target Neighborhood Hits	531	Shared Neighborhood Hits	84
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PHF22_HUMAN
NC score	0.095270 (rank : 191)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	472	Target Neighborhood Hits	121	Shared Neighborhood Hits	51
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SMCA2_HUMAN
NC score	0.095151 (rank : 192)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	472	Target Neighborhood Hits	503	Shared Neighborhood Hits	85
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ZAN_HUMAN
NC score	0.094833 (rank : 193)	θ value	0.000158464 (rank : 55)
Query Neighborhood Hits	472	Target Neighborhood Hits	679	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

RBBP6_HUMAN
NC score	0.093566 (rank : 194)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	472	Target Neighborhood Hits	1135	Shared Neighborhood Hits	142
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BRD2_HUMAN
NC score	0.092303 (rank : 195)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	58
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_MOUSE
NC score	0.091513 (rank : 196)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	472	Target Neighborhood Hits	402	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

TXND2_MOUSE
NC score	0.091483 (rank : 197)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	472	Target Neighborhood Hits	828	Shared Neighborhood Hits	106
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TRDN_HUMAN
NC score	0.091480 (rank : 198)	θ value	0.0330416 (rank : 112)
Query Neighborhood Hits	472	Target Neighborhood Hits	542	Shared Neighborhood Hits	60
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

OGFR_HUMAN
NC score	0.090279 (rank : 199)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	472	Target Neighborhood Hits	1582	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RBBP6_MOUSE
NC score	0.090074 (rank : 200)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	472	Target Neighborhood Hits	1014	Shared Neighborhood Hits	123
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

PRP2_MOUSE
NC score	0.089996 (rank : 201)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	472	Target Neighborhood Hits	347	Shared Neighborhood Hits	58
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

TP53B_MOUSE
NC score	0.089881 (rank : 202)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	472	Target Neighborhood Hits	644	Shared Neighborhood Hits	111
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DSPP_MOUSE
NC score	0.089862 (rank : 203)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	59
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GON4L_MOUSE
NC score	0.089744 (rank : 204)	θ value	0.0252991 (rank : 106)
Query Neighborhood Hits	472	Target Neighborhood Hits	455	Shared Neighborhood Hits	71
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

CJ012_HUMAN
NC score	0.089519 (rank : 205)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	472	Target Neighborhood Hits	467	Shared Neighborhood Hits	98
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

K1333_HUMAN
NC score	0.089220 (rank : 206)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	472	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

BRD3_HUMAN
NC score	0.088736 (rank : 207)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	472	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

TCOF_MOUSE
NC score	0.088640 (rank : 208)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	472	Target Neighborhood Hits	471	Shared Neighborhood Hits	87
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

GTSE1_HUMAN
NC score	0.088118 (rank : 209)	θ value	0.21417 (rank : 151)
Query Neighborhood Hits	472	Target Neighborhood Hits	193	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

ATN1_HUMAN
NC score	0.087871 (rank : 210)	θ value	0.47712 (rank : 187)
Query Neighborhood Hits	472	Target Neighborhood Hits	676	Shared Neighborhood Hits	96
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MINT_HUMAN
NC score	0.087237 (rank : 211)	θ value	0.47712 (rank : 190)
Query Neighborhood Hits	472	Target Neighborhood Hits	1291	Shared Neighborhood Hits	160
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRR12_HUMAN
NC score	0.086609 (rank : 212)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	472	Target Neighborhood Hits	460	Shared Neighborhood Hits	79
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

BASP_HUMAN
NC score	0.086373 (rank : 213)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	472	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CN155_HUMAN
NC score	0.086182 (rank : 214)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	80
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

PRP1_HUMAN
NC score	0.085840 (rank : 215)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	70
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

GCNL2_HUMAN
NC score	0.085835 (rank : 216)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	472	Target Neighborhood Hits	159	Shared Neighborhood Hits	43
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

K1802_HUMAN
NC score	0.085489 (rank : 217)	θ value	0.62314 (rank : 199)
Query Neighborhood Hits	472	Target Neighborhood Hits	1378	Shared Neighborhood Hits	142
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

WASIP_MOUSE
NC score	0.085069 (rank : 218)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	472	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

ZN750_MOUSE
NC score	0.084972 (rank : 219)	θ value	0.125558 (rank : 138)
Query Neighborhood Hits	472	Target Neighborhood Hits	346	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

FYB_HUMAN
NC score	0.084814 (rank : 220)	θ value	1.38821 (rank : 237)
Query Neighborhood Hits	472	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

FA47A_HUMAN
NC score	0.084290 (rank : 221)	θ value	8.99809 (rank : 430)
Query Neighborhood Hits	472	Target Neighborhood Hits	451	Shared Neighborhood Hits	79
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

WASIP_HUMAN
NC score	0.084249 (rank : 222)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	472	Target Neighborhood Hits	458	Shared Neighborhood Hits	78
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

GCNL2_MOUSE
NC score	0.084236 (rank : 223)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	472	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

MAGE1_HUMAN
NC score	0.084116 (rank : 224)	θ value	0.0330416 (rank : 110)
Query Neighborhood Hits	472	Target Neighborhood Hits	1389	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

BCL9_HUMAN
NC score	0.083912 (rank : 225)	θ value	3.0926 (rank : 287)
Query Neighborhood Hits	472	Target Neighborhood Hits	1008	Shared Neighborhood Hits	134
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BRDT_MOUSE
NC score	0.083835 (rank : 226)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	472	Target Neighborhood Hits	243	Shared Neighborhood Hits	56
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

ANK2_HUMAN
NC score	0.083342 (rank : 227)	θ value	0.365318 (rank : 168)
Query Neighborhood Hits	472	Target Neighborhood Hits	1615	Shared Neighborhood Hits	202
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CJ078_MOUSE
NC score	0.082989 (rank : 228)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	472	Target Neighborhood Hits	559	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

ARI1A_HUMAN
NC score	0.082899 (rank : 229)	θ value	2.36792 (rank : 265)
Query Neighborhood Hits	472	Target Neighborhood Hits	787	Shared Neighborhood Hits	99
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

EP400_MOUSE
NC score	0.082815 (rank : 230)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	472	Target Neighborhood Hits	592	Shared Neighborhood Hits	93
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

MAP1B_MOUSE
NC score	0.082635 (rank : 231)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	472	Target Neighborhood Hits	977	Shared Neighborhood Hits	124
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP4_MOUSE
NC score	0.082381 (rank : 232)	θ value	6.88961 (rank : 399)
Query Neighborhood Hits	472	Target Neighborhood Hits	409	Shared Neighborhood Hits	87
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

AKA12_HUMAN
NC score	0.082350 (rank : 233)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	472	Target Neighborhood Hits	825	Shared Neighborhood Hits	103
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

TCOF_HUMAN
NC score	0.081933 (rank : 234)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	101
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

CYLC2_HUMAN
NC score	0.081044 (rank : 235)	θ value	0.163984 (rank : 141)
Query Neighborhood Hits	472	Target Neighborhood Hits	223	Shared Neighborhood Hits	41
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

MINT_MOUSE
NC score	0.080904 (rank : 236)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	472	Target Neighborhood Hits	1514	Shared Neighborhood Hits	180
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PYGO2_HUMAN
NC score	0.080321 (rank : 237)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	472	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

BRDT_HUMAN
NC score	0.080038 (rank : 238)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	472	Target Neighborhood Hits	280	Shared Neighborhood Hits	44
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

PCAF_HUMAN
NC score	0.079841 (rank : 239)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	472	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

MPP8_HUMAN
NC score	0.079294 (rank : 240)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	472	Target Neighborhood Hits	948	Shared Neighborhood Hits	99
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MUC2_HUMAN
NC score	0.079197 (rank : 241)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	472	Target Neighborhood Hits	906	Shared Neighborhood Hits	104
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CHD6_HUMAN
NC score	0.079121 (rank : 242)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

FA47B_HUMAN
NC score	0.078962 (rank : 243)	θ value	4.03905 (rank : 319)
Query Neighborhood Hits	472	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SFRIP_HUMAN
NC score	0.078814 (rank : 244)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	472	Target Neighborhood Hits	530	Shared Neighborhood Hits	104
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CHD2_HUMAN
NC score	0.078538 (rank : 245)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	472	Target Neighborhood Hits	360	Shared Neighborhood Hits	46
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

PRG4_MOUSE
NC score	0.077949 (rank : 246)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	472	Target Neighborhood Hits	624	Shared Neighborhood Hits	98
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CHD1_HUMAN
NC score	0.077921 (rank : 247)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	472	Target Neighborhood Hits	337	Shared Neighborhood Hits	45
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

MUC1_HUMAN
NC score	0.077868 (rank : 248)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	472	Target Neighborhood Hits	975	Shared Neighborhood Hits	128
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RGS3_HUMAN
NC score	0.077781 (rank : 249)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	472	Target Neighborhood Hits	1375	Shared Neighborhood Hits	153
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PRRT3_HUMAN
NC score	0.077661 (rank : 250)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	472	Target Neighborhood Hits	998	Shared Neighborhood Hits	125
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

BSN_HUMAN
NC score	0.077543 (rank : 251)	θ value	8.99809 (rank : 422)
Query Neighborhood Hits	472	Target Neighborhood Hits	1537	Shared Neighborhood Hits	164
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CHD9_MOUSE
NC score	0.077505 (rank : 252)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

YLPM1_HUMAN
NC score	0.077261 (rank : 253)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	472	Target Neighborhood Hits	670	Shared Neighborhood Hits	95
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

MARCS_HUMAN
NC score	0.077102 (rank : 254)	θ value	4.03905 (rank : 325)
Query Neighborhood Hits	472	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

GGN_MOUSE
NC score	0.076942 (rank : 255)	θ value	1.81305 (rank : 255)
Query Neighborhood Hits	472	Target Neighborhood Hits	311	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

LEO1_MOUSE
NC score	0.076936 (rank : 256)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	472	Target Neighborhood Hits	946	Shared Neighborhood Hits	104
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

GRIN1_HUMAN
NC score	0.076428 (rank : 257)	θ value	3.0926 (rank : 295)
Query Neighborhood Hits	472	Target Neighborhood Hits	681	Shared Neighborhood Hits	102
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SYN1_MOUSE
NC score	0.076359 (rank : 258)	θ value	0.813845 (rank : 214)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	67
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

EP400_HUMAN
NC score	0.076328 (rank : 259)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	472	Target Neighborhood Hits	556	Shared Neighborhood Hits	79
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

TTF2_MOUSE
NC score	0.076069 (rank : 260)	θ value	0.813845 (rank : 216)
Query Neighborhood Hits	472	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

MAP4_HUMAN
NC score	0.076066 (rank : 261)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	472	Target Neighborhood Hits	428	Shared Neighborhood Hits	91
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

AFF2_MOUSE
NC score	0.075561 (rank : 262)	θ value	0.163984 (rank : 139)
Query Neighborhood Hits	472	Target Neighborhood Hits	225	Shared Neighborhood Hits	58
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

MBD6_HUMAN
NC score	0.075528 (rank : 263)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	472	Target Neighborhood Hits	349	Shared Neighborhood Hits	65
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

BAT2_MOUSE
NC score	0.075524 (rank : 264)	θ value	5.27518 (rank : 343)
Query Neighborhood Hits	472	Target Neighborhood Hits	947	Shared Neighborhood Hits	131
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TAF1_HUMAN
NC score	0.075409 (rank : 265)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	28
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

CHD9_HUMAN
NC score	0.075401 (rank : 266)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	472	Target Neighborhood Hits	343	Shared Neighborhood Hits	51
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

ACINU_HUMAN
NC score	0.075370 (rank : 267)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	472	Target Neighborhood Hits	828	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PB1_HUMAN
NC score	0.075277 (rank : 268)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	472	Target Neighborhood Hits	261	Shared Neighborhood Hits	41
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

CO002_HUMAN
NC score	0.075208 (rank : 269)	θ value	8.99809 (rank : 427)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CHD1_MOUSE
NC score	0.074946 (rank : 270)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	472	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

TARA_MOUSE
NC score	0.074487 (rank : 271)	θ value	2.36792 (rank : 281)
Query Neighborhood Hits	472	Target Neighborhood Hits	1133	Shared Neighborhood Hits	127
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SFR11_HUMAN
NC score	0.074325 (rank : 272)	θ value	8.99809 (rank : 458)
Query Neighborhood Hits	472	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

ZCPW1_HUMAN
NC score	0.074296 (rank : 273)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	472	Target Neighborhood Hits	116	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H0M4, Q8NA98, Q9BUD0, Q9NWF7	Gene names	ZCWPW1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1.

RAPH1_HUMAN
NC score	0.074130 (rank : 274)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	472	Target Neighborhood Hits	593	Shared Neighborhood Hits	99
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TAF4_HUMAN
NC score	0.074042 (rank : 275)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	472	Target Neighborhood Hits	687	Shared Neighborhood Hits	92
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CIR_MOUSE
NC score	0.073634 (rank : 276)	θ value	0.279714 (rank : 156)
Query Neighborhood Hits	472	Target Neighborhood Hits	255	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

TCAL5_HUMAN
NC score	0.073546 (rank : 277)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	472	Target Neighborhood Hits	806	Shared Neighborhood Hits	97
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

AL2S4_MOUSE
NC score	0.073293 (rank : 278)	θ value	0.813845 (rank : 202)
Query Neighborhood Hits	472	Target Neighborhood Hits	193	Shared Neighborhood Hits	45
SwissProt Accessions	Q3V0J1, Q3TIS2	Gene names	Als2cr4
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein homolog.

BCL9_MOUSE
NC score	0.073287 (rank : 279)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	472	Target Neighborhood Hits	770	Shared Neighborhood Hits	110
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

TAF1L_HUMAN
NC score	0.072892 (rank : 280)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

NFH_HUMAN
NC score	0.072550 (rank : 281)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	472	Target Neighborhood Hits	1242	Shared Neighborhood Hits	133
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CHD8_HUMAN
NC score	0.071802 (rank : 282)	θ value	6.88961 (rank : 384)
Query Neighborhood Hits	472	Target Neighborhood Hits	235	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

PDZD2_HUMAN
NC score	0.071576 (rank : 283)	θ value	0.47712 (rank : 191)
Query Neighborhood Hits	472	Target Neighborhood Hits	772	Shared Neighborhood Hits	96
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

TRI45_HUMAN
NC score	0.071385 (rank : 284)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	472	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

RTP3_MOUSE
NC score	0.071205 (rank : 285)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	472	Target Neighborhood Hits	374	Shared Neighborhood Hits	81
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

BAG3_MOUSE
NC score	0.071007 (rank : 286)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	472	Target Neighborhood Hits	513	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

DMP1_HUMAN
NC score	0.070982 (rank : 287)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	472	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TRI45_MOUSE
NC score	0.070912 (rank : 288)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	472	Target Neighborhood Hits	155	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

NFRKB_MOUSE
NC score	0.070758 (rank : 289)	θ value	0.813845 (rank : 207)
Query Neighborhood Hits	472	Target Neighborhood Hits	393	Shared Neighborhood Hits	67
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ICAL_HUMAN
NC score	0.070623 (rank : 290)	θ value	1.06291 (rank : 221)
Query Neighborhood Hits	472	Target Neighborhood Hits	275	Shared Neighborhood Hits	65
SwissProt Accessions	P20810, O95360, Q96D08, Q9H1Z5	Gene names	CAST
Domain Architecture
Description	Calpastatin (Calpain inhibitor) (Sperm BS-17 component).

YLPM1_MOUSE
NC score	0.070600 (rank : 291)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	472	Target Neighborhood Hits	505	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

RERE_MOUSE
NC score	0.070280 (rank : 292)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	472	Target Neighborhood Hits	785	Shared Neighborhood Hits	110
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

NASP_HUMAN
NC score	0.070120 (rank : 293)	θ value	8.99809 (rank : 446)
Query Neighborhood Hits	472	Target Neighborhood Hits	709	Shared Neighborhood Hits	78
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

SYN1_HUMAN
NC score	0.069537 (rank : 294)	θ value	8.99809 (rank : 463)
Query Neighborhood Hits	472	Target Neighborhood Hits	419	Shared Neighborhood Hits	84
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

ALEX_HUMAN
NC score	0.069427 (rank : 295)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	472	Target Neighborhood Hits	361	Shared Neighborhood Hits	73
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CO039_MOUSE
NC score	0.069221 (rank : 296)	θ value	5.27518 (rank : 346)
Query Neighborhood Hits	472	Target Neighborhood Hits	445	Shared Neighborhood Hits	86
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MUC5B_HUMAN
NC score	0.069042 (rank : 297)	θ value	0.279714 (rank : 160)
Query Neighborhood Hits	472	Target Neighborhood Hits	1020	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CK024_HUMAN
NC score	0.069010 (rank : 298)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	81
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

LEO1_HUMAN
NC score	0.068763 (rank : 299)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	472	Target Neighborhood Hits	958	Shared Neighborhood Hits	104
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

WIRE_HUMAN
NC score	0.068640 (rank : 300)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	472	Target Neighborhood Hits	329	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

CBX3_MOUSE
NC score	0.068587 (rank : 301)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

MUC1_MOUSE
NC score	0.068371 (rank : 302)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	67
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CBX3_HUMAN
NC score	0.068119 (rank : 303)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	472	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

BAT2_HUMAN
NC score	0.068079 (rank : 304)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	472	Target Neighborhood Hits	931	Shared Neighborhood Hits	124
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DNMT1_HUMAN
NC score	0.067682 (rank : 305)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	472	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

ENL_HUMAN
NC score	0.067345 (rank : 306)	θ value	3.0926 (rank : 293)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	63
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

BRD9_MOUSE
NC score	0.067203 (rank : 307)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UQU0, Q5FWH1, Q811F7	Gene names	Brd9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9.

RERE_HUMAN
NC score	0.067136 (rank : 308)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	472	Target Neighborhood Hits	779	Shared Neighborhood Hits	108
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MAVS_HUMAN
NC score	0.067094 (rank : 309)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	472	Target Neighborhood Hits	271	Shared Neighborhood Hits	52
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

BRD7_HUMAN
NC score	0.067032 (rank : 310)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	472	Target Neighborhood Hits	94	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

TAU_MOUSE
NC score	0.066493 (rank : 311)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	472	Target Neighborhood Hits	502	Shared Neighborhood Hits	89
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MBB1A_HUMAN
NC score	0.066329 (rank : 312)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	472	Target Neighborhood Hits	665	Shared Neighborhood Hits	108
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

TM108_MOUSE
NC score	0.066310 (rank : 313)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	472	Target Neighborhood Hits	336	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

TIP60_MOUSE
NC score	0.066116 (rank : 314)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

TIP60_HUMAN
NC score	0.066068 (rank : 315)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	472	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

AFF1_HUMAN
NC score	0.065999 (rank : 316)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	472	Target Neighborhood Hits	506	Shared Neighborhood Hits	87
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CBX5_HUMAN
NC score	0.065934 (rank : 317)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	472	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

DNM3L_MOUSE
NC score	0.065916 (rank : 318)	θ value	3.0926 (rank : 291)
Query Neighborhood Hits	472	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CWR8	Gene names	Dnmt3l
Domain Architecture	No domain graphic available
Description	DNA (cytosine-5)-methyltransferase 3-like.

PML_HUMAN
NC score	0.065814 (rank : 319)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	472	Target Neighborhood Hits	248	Shared Neighborhood Hits	35
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

ARI1B_HUMAN
NC score	0.064782 (rank : 320)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	472	Target Neighborhood Hits	567	Shared Neighborhood Hits	90
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

OGFR_MOUSE
NC score	0.064551 (rank : 321)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	472	Target Neighborhood Hits	584	Shared Neighborhood Hits	93
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

ERCC6_HUMAN
NC score	0.064467 (rank : 322)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	472	Target Neighborhood Hits	247	Shared Neighborhood Hits	24
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

PRB4S_HUMAN
NC score	0.064423 (rank : 323)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	472	Target Neighborhood Hits	330	Shared Neighborhood Hits	62
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SMCA1_HUMAN
NC score	0.064297 (rank : 324)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	472	Target Neighborhood Hits	105	Shared Neighborhood Hits	16
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
NC score	0.064220 (rank : 325)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

CBX5_MOUSE
NC score	0.063858 (rank : 326)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	472	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

SRCH_HUMAN
NC score	0.063824 (rank : 327)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	472	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

RUSC1_HUMAN
NC score	0.063576 (rank : 328)	θ value	0.000786445 (rank : 63)
Query Neighborhood Hits	472	Target Neighborhood Hits	226	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

GTSE1_MOUSE
NC score	0.063425 (rank : 329)	θ value	2.36792 (rank : 273)
Query Neighborhood Hits	472	Target Neighborhood Hits	245	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

PI5PA_HUMAN
NC score	0.063128 (rank : 330)	θ value	8.99809 (rank : 451)
Query Neighborhood Hits	472	Target Neighborhood Hits	749	Shared Neighborhood Hits	123
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

IASPP_MOUSE
NC score	0.062861 (rank : 331)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	472	Target Neighborhood Hits	1024	Shared Neighborhood Hits	103
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

BRD7_MOUSE
NC score	0.062726 (rank : 332)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	36
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

BRD9_HUMAN
NC score	0.062692 (rank : 333)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H8M2, Q2XUS1, Q6UWU9, Q8IUS4, Q9H5Q5, Q9H7R9	Gene names	BRD9
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 9 (Rhabdomyosarcoma antigen MU-RMS- 40.8).

SMCA5_MOUSE
NC score	0.062674 (rank : 334)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	472	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA5_HUMAN
NC score	0.062618 (rank : 335)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	472	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMAL1_HUMAN
NC score	0.062616 (rank : 336)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

PO121_HUMAN
NC score	0.062592 (rank : 337)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	472	Target Neighborhood Hits	344	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

DNM3B_HUMAN
NC score	0.062506 (rank : 338)	θ value	1.81305 (rank : 252)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBC3, Q9UBD4, Q9UJQ5, Q9UKA6, Q9UNE5, Q9Y5R9, Q9Y5S0	Gene names	DNMT3B
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB).

ANR11_HUMAN
NC score	0.062024 (rank : 339)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	472	Target Neighborhood Hits	1289	Shared Neighborhood Hits	148
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

LR37A_HUMAN
NC score	0.061901 (rank : 340)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	472	Target Neighborhood Hits	720	Shared Neighborhood Hits	93
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PO121_MOUSE
NC score	0.061739 (rank : 341)	θ value	1.81305 (rank : 261)
Query Neighborhood Hits	472	Target Neighborhood Hits	345	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

TP53B_HUMAN
NC score	0.061463 (rank : 342)	θ value	3.0926 (rank : 310)
Query Neighborhood Hits	472	Target Neighborhood Hits	413	Shared Neighborhood Hits	68
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SAPS1_HUMAN
NC score	0.061426 (rank : 343)	θ value	1.38821 (rank : 245)
Query Neighborhood Hits	472	Target Neighborhood Hits	704	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

AN30A_HUMAN
NC score	0.061294 (rank : 344)	θ value	0.00390308 (rank : 86)
Query Neighborhood Hits	472	Target Neighborhood Hits	1119	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CT174_HUMAN
NC score	0.060946 (rank : 345)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	34
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

RAD54_HUMAN
NC score	0.060934 (rank : 346)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

AFF4_MOUSE
NC score	0.060792 (rank : 347)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

NSBP1_MOUSE
NC score	0.060718 (rank : 348)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	472	Target Neighborhood Hits	681	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

GGN_HUMAN
NC score	0.060489 (rank : 349)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	63
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

BASP_MOUSE
NC score	0.060439 (rank : 350)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	472	Target Neighborhood Hits	260	Shared Neighborhood Hits	44
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

SMAL1_MOUSE
NC score	0.060411 (rank : 351)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	472	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

WBP4_MOUSE
NC score	0.060220 (rank : 352)	θ value	0.62314 (rank : 201)
Query Neighborhood Hits	472	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

RAD54_MOUSE
NC score	0.060184 (rank : 353)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

SETD7_MOUSE
NC score	0.060115 (rank : 354)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

PHF2_MOUSE
NC score	0.060087 (rank : 355)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	472	Target Neighborhood Hits	241	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

TAU_HUMAN
NC score	0.060015 (rank : 356)	θ value	1.06291 (rank : 228)
Query Neighborhood Hits	472	Target Neighborhood Hits	448	Shared Neighborhood Hits	81
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SETD7_HUMAN
NC score	0.059828 (rank : 357)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

AFF4_HUMAN
NC score	0.059768 (rank : 358)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	472	Target Neighborhood Hits	611	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

MUC13_MOUSE
NC score	0.059552 (rank : 359)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	472	Target Neighborhood Hits	447	Shared Neighborhood Hits	63
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SMRCD_HUMAN
NC score	0.059529 (rank : 360)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

CBX1_HUMAN
NC score	0.059500 (rank : 361)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.059500 (rank : 362)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

NU214_HUMAN
NC score	0.059227 (rank : 363)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	472	Target Neighborhood Hits	657	Shared Neighborhood Hits	93
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RA54B_HUMAN
NC score	0.059131 (rank : 364)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	472	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

ADDB_MOUSE
NC score	0.059037 (rank : 365)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	472	Target Neighborhood Hits	574	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

MILK1_HUMAN
NC score	0.058828 (rank : 366)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	472	Target Neighborhood Hits	427	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MILK1_MOUSE
NC score	0.058776 (rank : 367)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	472	Target Neighborhood Hits	788	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RA54B_MOUSE
NC score	0.058771 (rank : 368)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	472	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

T2FA_HUMAN
NC score	0.058748 (rank : 369)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	42
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

SMRCD_MOUSE
NC score	0.058547 (rank : 370)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	472	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

JHD1B_HUMAN
NC score	0.058421 (rank : 371)	θ value	0.279714 (rank : 158)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

PML_MOUSE
NC score	0.058172 (rank : 372)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	472	Target Neighborhood Hits	246	Shared Neighborhood Hits	24
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

WIRE_MOUSE
NC score	0.057915 (rank : 373)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	472	Target Neighborhood Hits	310	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MYST2_MOUSE
NC score	0.057781 (rank : 374)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	472	Target Neighborhood Hits	87	Shared Neighborhood Hits	14
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_HUMAN
NC score	0.057574 (rank : 375)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	472	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

SMYD3_HUMAN
NC score	0.057350 (rank : 376)	θ value	8.99809 (rank : 461)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

DOT1L_HUMAN
NC score	0.057318 (rank : 377)	θ value	6.88961 (rank : 389)
Query Neighborhood Hits	472	Target Neighborhood Hits	660	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

INOC1_MOUSE
NC score	0.057228 (rank : 378)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.057077 (rank : 379)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

PHF2_HUMAN
NC score	0.056875 (rank : 380)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	472	Target Neighborhood Hits	208	Shared Neighborhood Hits	60
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

CIZ1_HUMAN
NC score	0.056611 (rank : 381)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	472	Target Neighborhood Hits	359	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

DMP1_MOUSE
NC score	0.056589 (rank : 382)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PCSK5_MOUSE
NC score	0.056552 (rank : 383)	θ value	7.1131e-05 (rank : 49)
Query Neighborhood Hits	472	Target Neighborhood Hits	613	Shared Neighborhood Hits	33
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CD2_HUMAN
NC score	0.056471 (rank : 384)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	472	Target Neighborhood Hits	504	Shared Neighborhood Hits	60
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

SMYD3_MOUSE
NC score	0.056377 (rank : 385)	θ value	8.99809 (rank : 462)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

JHD1B_MOUSE
NC score	0.056225 (rank : 386)	θ value	0.813845 (rank : 204)
Query Neighborhood Hits	472	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

ARI5B_HUMAN
NC score	0.056217 (rank : 387)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	472	Target Neighborhood Hits	328	Shared Neighborhood Hits	68
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CIC_HUMAN
NC score	0.056143 (rank : 388)	θ value	8.99809 (rank : 425)
Query Neighborhood Hits	472	Target Neighborhood Hits	992	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LCP2_MOUSE
NC score	0.056091 (rank : 389)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	472	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q60787	Gene names	Lcp2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ENAH_MOUSE
NC score	0.056018 (rank : 390)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	472	Target Neighborhood Hits	919	Shared Neighborhood Hits	96
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PSL1_HUMAN
NC score	0.055980 (rank : 391)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	472	Target Neighborhood Hits	650	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

DNM3B_MOUSE
NC score	0.055920 (rank : 392)	θ value	1.81305 (rank : 253)
Query Neighborhood Hits	472	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	O88509, O88510, O88511	Gene names	Dnmt3b
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3B (EC 2.1.1.37) (Dnmt3b) (DNA methyltransferase MmuIIIB) (DNA MTase MmuIIIB) (M.MmuIIIB).

SFRS8_HUMAN
NC score	0.055783 (rank : 393)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	472	Target Neighborhood Hits	166	Shared Neighborhood Hits	32
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

DNMT1_MOUSE
NC score	0.055740 (rank : 394)	θ value	0.62314 (rank : 196)
Query Neighborhood Hits	472	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

RPB1_MOUSE
NC score	0.055564 (rank : 395)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	61
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ASPP1_MOUSE
NC score	0.055531 (rank : 396)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	472	Target Neighborhood Hits	1244	Shared Neighborhood Hits	127
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

RPB1_HUMAN
NC score	0.055415 (rank : 397)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	472	Target Neighborhood Hits	362	Shared Neighborhood Hits	62
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CABIN_HUMAN
NC score	0.055264 (rank : 398)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	472	Target Neighborhood Hits	490	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

SFR15_HUMAN
NC score	0.055093 (rank : 399)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	472	Target Neighborhood Hits	368	Shared Neighborhood Hits	55
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

MSH6_MOUSE
NC score	0.055085 (rank : 400)	θ value	6.88961 (rank : 400)
Query Neighborhood Hits	472	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

MYST1_HUMAN
NC score	0.055070 (rank : 401)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	472	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
NC score	0.055015 (rank : 402)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	472	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

GRIN1_MOUSE
NC score	0.055006 (rank : 403)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	472	Target Neighborhood Hits	337	Shared Neighborhood Hits	70
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

BTAF1_HUMAN
NC score	0.054748 (rank : 404)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	472	Target Neighborhood Hits	97	Shared Neighborhood Hits	13
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

HTSF1_HUMAN
NC score	0.054667 (rank : 405)	θ value	0.125558 (rank : 134)
Query Neighborhood Hits	472	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

T22D2_HUMAN
NC score	0.054620 (rank : 406)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	472	Target Neighborhood Hits	250	Shared Neighborhood Hits	51
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PRB3_HUMAN
NC score	0.054576 (rank : 407)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	472	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

K0310_HUMAN
NC score	0.054522 (rank : 408)	θ value	8.99809 (rank : 439)
Query Neighborhood Hits	472	Target Neighborhood Hits	420	Shared Neighborhood Hits	57
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CN032_MOUSE
NC score	0.054469 (rank : 409)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	472	Target Neighborhood Hits	233	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

TRI56_HUMAN
NC score	0.054327 (rank : 410)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	472	Target Neighborhood Hits	339	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

SHAN1_HUMAN
NC score	0.054313 (rank : 411)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	472	Target Neighborhood Hits	1041	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

CSKI1_MOUSE
NC score	0.054037 (rank : 412)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	472	Target Neighborhood Hits	1031	Shared Neighborhood Hits	124
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GON4L_HUMAN
NC score	0.053884 (rank : 413)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	472	Target Neighborhood Hits	555	Shared Neighborhood Hits	84
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

SYNJ1_HUMAN
NC score	0.053636 (rank : 414)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	472	Target Neighborhood Hits	498	Shared Neighborhood Hits	96
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CCNK_MOUSE
NC score	0.053574 (rank : 415)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	472	Target Neighborhood Hits	350	Shared Neighborhood Hits	56
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

AUTS2_HUMAN
NC score	0.053448 (rank : 416)	θ value	5.27518 (rank : 342)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

CRSP7_HUMAN
NC score	0.053381 (rank : 417)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	472	Target Neighborhood Hits	247	Shared Neighborhood Hits	39
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CASC3_MOUSE
NC score	0.052974 (rank : 418)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	472	Target Neighborhood Hits	333	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

K1543_MOUSE
NC score	0.052905 (rank : 419)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	472	Target Neighborhood Hits	497	Shared Neighborhood Hits	85
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

CK024_MOUSE
NC score	0.052872 (rank : 420)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

ZAN_MOUSE
NC score	0.052643 (rank : 421)	θ value	1.38821 (rank : 248)
Query Neighborhood Hits	472	Target Neighborhood Hits	808	Shared Neighborhood Hits	59
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MSH6_HUMAN
NC score	0.052279 (rank : 422)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	472	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	P52701, O43706, O43917, Q8TCX4, Q9BTB5	Gene names	MSH6, GTBP
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

EMSY_MOUSE
NC score	0.052029 (rank : 423)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	472	Target Neighborhood Hits	294	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

ZN207_HUMAN
NC score	0.052014 (rank : 424)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	472	Target Neighborhood Hits	326	Shared Neighborhood Hits	41
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

PCQAP_HUMAN
NC score	0.051998 (rank : 425)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	472	Target Neighborhood Hits	549	Shared Neighborhood Hits	61
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

DPF3_MOUSE
NC score	0.051845 (rank : 426)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	472	Target Neighborhood Hits	327	Shared Neighborhood Hits	16
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

SGIP1_MOUSE
NC score	0.051691 (rank : 427)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	472	Target Neighborhood Hits	180	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TIM44_MOUSE
NC score	0.051678 (rank : 428)	θ value	0.163984 (rank : 150)
Query Neighborhood Hits	472	Target Neighborhood Hits	235	Shared Neighborhood Hits	22
SwissProt Accessions	O35857	Gene names	Timm44, Mimt44, Tim44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

MYCB2_MOUSE
NC score	0.051436 (rank : 429)	θ value	0.279714 (rank : 161)
Query Neighborhood Hits	472	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

APC_HUMAN
NC score	0.051329 (rank : 430)	θ value	2.36792 (rank : 264)
Query Neighborhood Hits	472	Target Neighborhood Hits	603	Shared Neighborhood Hits	83
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

TACC1_MOUSE
NC score	0.051252 (rank : 431)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	472	Target Neighborhood Hits	667	Shared Neighborhood Hits	63
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

SGIP1_HUMAN
NC score	0.051240 (rank : 432)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	472	Target Neighborhood Hits	198	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

MARCS_MOUSE
NC score	0.051111 (rank : 433)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	472	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MYCB2_HUMAN
NC score	0.051053 (rank : 434)	θ value	3.0926 (rank : 301)
Query Neighborhood Hits	472	Target Neighborhood Hits	390	Shared Neighborhood Hits	69
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PHF3_HUMAN
NC score	0.051023 (rank : 435)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	472	Target Neighborhood Hits	419	Shared Neighborhood Hits	62
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SETBP_MOUSE
NC score	0.051022 (rank : 436)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	472	Target Neighborhood Hits	352	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

CBX2_HUMAN
NC score	0.050997 (rank : 437)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	472	Target Neighborhood Hits	264	Shared Neighborhood Hits	45
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

SNPC4_HUMAN
NC score	0.050992 (rank : 438)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	472	Target Neighborhood Hits	589	Shared Neighborhood Hits	90
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SYNJ1_MOUSE
NC score	0.050911 (rank : 439)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	472	Target Neighborhood Hits	516	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CSKI1_HUMAN
NC score	0.050871 (rank : 440)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	472	Target Neighborhood Hits	997	Shared Neighborhood Hits	110
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SLC2B_HUMAN
NC score	0.050810 (rank : 441)	θ value	2.36792 (rank : 280)
Query Neighborhood Hits	472	Target Neighborhood Hits	214	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

PPRB_MOUSE
NC score	0.050703 (rank : 442)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	472	Target Neighborhood Hits	354	Shared Neighborhood Hits	61
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

CN032_HUMAN
NC score	0.050702 (rank : 443)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	472	Target Neighborhood Hits	267	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

MAP2_MOUSE
NC score	0.050610 (rank : 444)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	472	Target Neighborhood Hits	342	Shared Neighborhood Hits	67
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

TRI56_MOUSE
NC score	0.050533 (rank : 445)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	472	Target Neighborhood Hits	255	Shared Neighborhood Hits	19
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

RUSC2_MOUSE
NC score	0.050456 (rank : 446)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	49
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

BRAP_MOUSE
NC score	0.050191 (rank : 447)	θ value	0.365318 (rank : 170)
Query Neighborhood Hits	472	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

FXL19_HUMAN
NC score	0.050152 (rank : 448)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

WBP11_MOUSE
NC score	0.050114 (rank : 449)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	472	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

RP1L1_HUMAN
NC score	0.050108 (rank : 450)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	472	Target Neighborhood Hits	1072	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

PELP1_HUMAN
NC score	0.050036 (rank : 451)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	472	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

CSKI2_HUMAN
NC score	0.050020 (rank : 452)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	472	Target Neighborhood Hits	747	Shared Neighborhood Hits	80
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TATD2_HUMAN
NC score	0.049245 (rank : 453)	θ value	0.813845 (rank : 215)
Query Neighborhood Hits	472	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

CEND_HUMAN
NC score	0.049234 (rank : 454)	θ value	2.36792 (rank : 268)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N111, Q9NYM6	Gene names	CEND1, BM88
Domain Architecture	No domain graphic available
Description	Cell cycle exit and neuronal differentiation protein 1 (BM88 antigen).

CIC_MOUSE
NC score	0.049183 (rank : 455)	θ value	6.88961 (rank : 385)
Query Neighborhood Hits	472	Target Neighborhood Hits	742	Shared Neighborhood Hits	109
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

3BP1_HUMAN
NC score	0.049030 (rank : 456)	θ value	1.81305 (rank : 249)
Query Neighborhood Hits	472	Target Neighborhood Hits	376	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ENAM_HUMAN
NC score	0.048543 (rank : 457)	θ value	1.81305 (rank : 254)
Query Neighborhood Hits	472	Target Neighborhood Hits	227	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

INVS_MOUSE
NC score	0.047970 (rank : 458)	θ value	8.99809 (rank : 437)
Query Neighborhood Hits	472	Target Neighborhood Hits	609	Shared Neighborhood Hits	75
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

NKTR_HUMAN
NC score	0.047814 (rank : 459)	θ value	8.99809 (rank : 448)
Query Neighborhood Hits	472	Target Neighborhood Hits	658	Shared Neighborhood Hits	85
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TIM44_HUMAN
NC score	0.047791 (rank : 460)	θ value	0.365318 (rank : 182)
Query Neighborhood Hits	472	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	O43615, Q8N193	Gene names	TIMM44, MIMT44, TIM44
Domain Architecture
Description	Import inner membrane translocase subunit TIM44, mitochondrial precursor.

BLNK_MOUSE
NC score	0.047673 (rank : 461)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	472	Target Neighborhood Hits	296	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

IRS2_HUMAN
NC score	0.047386 (rank : 462)	θ value	0.813845 (rank : 203)
Query Neighborhood Hits	472	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y4H2, Q96RR2, Q9BZG0, Q9Y6I5	Gene names	IRS2
Domain Architecture
Description	Insulin receptor substrate 2 (IRS-2).

NFRKB_HUMAN
NC score	0.047253 (rank : 463)	θ value	8.99809 (rank : 447)
Query Neighborhood Hits	472	Target Neighborhood Hits	211	Shared Neighborhood Hits	44
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

K0329_HUMAN
NC score	0.047194 (rank : 464)	θ value	0.125558 (rank : 135)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

BRAP_HUMAN
NC score	0.047103 (rank : 465)	θ value	0.365318 (rank : 169)
Query Neighborhood Hits	472	Target Neighborhood Hits	560	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BCL3_MOUSE
NC score	0.047054 (rank : 466)	θ value	0.0563607 (rank : 119)
Query Neighborhood Hits	472	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

SETBP_HUMAN
NC score	0.046553 (rank : 467)	θ value	6.88961 (rank : 410)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

AB1IP_MOUSE
NC score	0.046215 (rank : 468)	θ value	0.47712 (rank : 186)
Query Neighborhood Hits	472	Target Neighborhood Hits	181	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

SNPC2_MOUSE
NC score	0.046080 (rank : 469)	θ value	0.47712 (rank : 193)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	25
SwissProt Accessions	Q91XA5, Q3UK17, Q8CBS9	Gene names	Snapc2
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2).

RTN4_HUMAN
NC score	0.045272 (rank : 470)	θ value	6.88961 (rank : 409)
Query Neighborhood Hits	472	Target Neighborhood Hits	357	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RUSC1_MOUSE
NC score	0.045263 (rank : 471)	θ value	1.38821 (rank : 244)
Query Neighborhood Hits	472	Target Neighborhood Hits	206	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

GASP2_MOUSE
NC score	0.044408 (rank : 472)	θ value	0.62314 (rank : 198)
Query Neighborhood Hits	472	Target Neighborhood Hits	228	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

RIMB1_HUMAN
NC score	0.044238 (rank : 473)	θ value	1.38821 (rank : 242)
Query Neighborhood Hits	472	Target Neighborhood Hits	1479	Shared Neighborhood Hits	110
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIMB1_MOUSE
NC score	0.043761 (rank : 474)	θ value	0.279714 (rank : 164)
Query Neighborhood Hits	472	Target Neighborhood Hits	1376	Shared Neighborhood Hits	95
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BRWD1_HUMAN
NC score	0.043177 (rank : 475)	θ value	8.99809 (rank : 421)
Query Neighborhood Hits	472	Target Neighborhood Hits	448	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

SFR12_MOUSE
NC score	0.043064 (rank : 476)	θ value	8.99809 (rank : 459)
Query Neighborhood Hits	472	Target Neighborhood Hits	486	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

DDEF1_MOUSE
NC score	0.042506 (rank : 477)	θ value	0.163984 (rank : 142)
Query Neighborhood Hits	472	Target Neighborhood Hits	592	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

S23IP_MOUSE
NC score	0.042300 (rank : 478)	θ value	8.99809 (rank : 457)
Query Neighborhood Hits	472	Target Neighborhood Hits	363	Shared Neighborhood Hits	49
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

NOL8_HUMAN
NC score	0.042040 (rank : 479)	θ value	3.0926 (rank : 302)
Query Neighborhood Hits	472	Target Neighborhood Hits	297	Shared Neighborhood Hits	38
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

PPIG_HUMAN
NC score	0.041965 (rank : 480)	θ value	0.21417 (rank : 155)
Query Neighborhood Hits	472	Target Neighborhood Hits	670	Shared Neighborhood Hits	85
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RASF7_HUMAN
NC score	0.041124 (rank : 481)	θ value	0.163984 (rank : 148)
Query Neighborhood Hits	472	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

MKL2_MOUSE
NC score	0.040935 (rank : 482)	θ value	5.27518 (rank : 357)
Query Neighborhood Hits	472	Target Neighborhood Hits	269	Shared Neighborhood Hits	40
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

BCL3_HUMAN
NC score	0.040853 (rank : 483)	θ value	0.47712 (rank : 188)
Query Neighborhood Hits	472	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

AB1IP_HUMAN
NC score	0.040762 (rank : 484)	θ value	3.0926 (rank : 284)
Query Neighborhood Hits	472	Target Neighborhood Hits	213	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

VPS41_HUMAN
NC score	0.040381 (rank : 485)	θ value	0.813845 (rank : 217)
Query Neighborhood Hits	472	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

PAIRB_MOUSE
NC score	0.040250 (rank : 486)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	472	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CY58, Q8BHS2, Q8BHU0, Q91WP3, Q9CSN0, Q9DBY6	Gene names	Serbp1, Pairbp1
Domain Architecture	No domain graphic available
Description	Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA- binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1).

MKL2_HUMAN
NC score	0.040043 (rank : 487)	θ value	5.27518 (rank : 356)
Query Neighborhood Hits	472	Target Neighborhood Hits	274	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

RFIP1_HUMAN
NC score	0.039930 (rank : 488)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	472	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

K0423_HUMAN
NC score	0.039721 (rank : 489)	θ value	8.99809 (rank : 440)
Query Neighborhood Hits	472	Target Neighborhood Hits	171	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

PAIRB_HUMAN
NC score	0.039714 (rank : 490)	θ value	4.03905 (rank : 328)
Query Neighborhood Hits	472	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC51, Q8WUH0, Q96SE2, Q9BTY3, Q9BUM4, Q9Y367, Q9Y4S3	Gene names	SERBP1, PAIRBP1
Domain Architecture	No domain graphic available
Description	Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA- binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1).

XRCC1_MOUSE
NC score	0.039372 (rank : 491)	θ value	3.0926 (rank : 313)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

PARM1_MOUSE
NC score	0.039337 (rank : 492)	θ value	6.88961 (rank : 403)
Query Neighborhood Hits	472	Target Neighborhood Hits	140	Shared Neighborhood Hits	23
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

IF4G1_HUMAN
NC score	0.039300 (rank : 493)	θ value	4.03905 (rank : 322)
Query Neighborhood Hits	472	Target Neighborhood Hits	347	Shared Neighborhood Hits	67
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

FGD1_MOUSE
NC score	0.039045 (rank : 494)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	52
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SYP2L_HUMAN
NC score	0.038975 (rank : 495)	θ value	1.06291 (rank : 227)
Query Neighborhood Hits	472	Target Neighborhood Hits	400	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

CEP35_HUMAN
NC score	0.038838 (rank : 496)	θ value	5.27518 (rank : 345)
Query Neighborhood Hits	472	Target Neighborhood Hits	811	Shared Neighborhood Hits	78
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NEST_HUMAN
NC score	0.038752 (rank : 497)	θ value	5.27518 (rank : 358)
Query Neighborhood Hits	472	Target Neighborhood Hits	1305	Shared Neighborhood Hits	108
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

COFA1_HUMAN
NC score	0.038313 (rank : 498)	θ value	0.0431538 (rank : 115)
Query Neighborhood Hits	472	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

PHLB1_HUMAN
NC score	0.037818 (rank : 499)	θ value	5.27518 (rank : 360)
Query Neighborhood Hits	472	Target Neighborhood Hits	1038	Shared Neighborhood Hits	100
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MYCD_HUMAN
NC score	0.037739 (rank : 500)	θ value	1.81305 (rank : 260)
Query Neighborhood Hits	472	Target Neighborhood Hits	167	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

SMYD5_HUMAN
NC score	0.037405 (rank : 501)	θ value	1.06291 (rank : 226)
Query Neighborhood Hits	472	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q6GMV2, Q13558	Gene names	SMYD5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

HUWE1_MOUSE
NC score	0.036864 (rank : 502)	θ value	0.0431538 (rank : 116)
Query Neighborhood Hits	472	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

TENS1_HUMAN
NC score	0.036847 (rank : 503)	θ value	3.0926 (rank : 309)
Query Neighborhood Hits	472	Target Neighborhood Hits	400	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

LMD1_HUMAN
NC score	0.036778 (rank : 504)	θ value	0.813845 (rank : 205)
Query Neighborhood Hits	472	Target Neighborhood Hits	169	Shared Neighborhood Hits	33
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

FRAS1_HUMAN
NC score	0.036490 (rank : 505)	θ value	0.365318 (rank : 172)
Query Neighborhood Hits	472	Target Neighborhood Hits	759	Shared Neighborhood Hits	38
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IF4B_HUMAN
NC score	0.036279 (rank : 506)	θ value	6.88961 (rank : 395)
Query Neighborhood Hits	472	Target Neighborhood Hits	417	Shared Neighborhood Hits	53
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TACC2_HUMAN
NC score	0.035289 (rank : 507)	θ value	3.0926 (rank : 308)
Query Neighborhood Hits	472	Target Neighborhood Hits	856	Shared Neighborhood Hits	81
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ZYX_HUMAN
NC score	0.034833 (rank : 508)	θ value	5.27518 (rank : 375)
Query Neighborhood Hits	472	Target Neighborhood Hits	387	Shared Neighborhood Hits	54
SwissProt Accessions	Q15942	Gene names	ZYX
Domain Architecture
Description	Zyxin (Zyxin-2).

IF35_HUMAN
NC score	0.034743 (rank : 509)	θ value	2.36792 (rank : 274)
Query Neighborhood Hits	472	Target Neighborhood Hits	130	Shared Neighborhood Hits	27
SwissProt Accessions	O00303, Q8N978	Gene names	EIF3S5
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 5 (eIF-3 epsilon) (eIF3 p47 subunit) (eIF3f).

GNAS1_MOUSE
NC score	0.034717 (rank : 510)	θ value	6.88961 (rank : 392)
Query Neighborhood Hits	472	Target Neighborhood Hits	651	Shared Neighborhood Hits	87
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

RBM16_HUMAN
NC score	0.034472 (rank : 511)	θ value	6.88961 (rank : 407)
Query Neighborhood Hits	472	Target Neighborhood Hits	300	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

TACC2_MOUSE
NC score	0.034450 (rank : 512)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	472	Target Neighborhood Hits	774	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

IF2P_HUMAN
NC score	0.034278 (rank : 513)	θ value	8.99809 (rank : 436)
Query Neighborhood Hits	472	Target Neighborhood Hits	889	Shared Neighborhood Hits	66
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

TULP1_MOUSE
NC score	0.032664 (rank : 514)	θ value	0.365318 (rank : 183)
Query Neighborhood Hits	472	Target Neighborhood Hits	146	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

BMPER_HUMAN
NC score	0.032618 (rank : 515)	θ value	4.03905 (rank : 317)
Query Neighborhood Hits	472	Target Neighborhood Hits	175	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LRC56_HUMAN
NC score	0.032429 (rank : 516)	θ value	1.38821 (rank : 240)
Query Neighborhood Hits	472	Target Neighborhood Hits	165	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

LDB3_MOUSE
NC score	0.032377 (rank : 517)	θ value	3.0926 (rank : 298)
Query Neighborhood Hits	472	Target Neighborhood Hits	510	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

TRIPC_HUMAN
NC score	0.032254 (rank : 518)	θ value	6.88961 (rank : 416)
Query Neighborhood Hits	472	Target Neighborhood Hits	319	Shared Neighborhood Hits	57
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

TEX15_HUMAN
NC score	0.032228 (rank : 519)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	472	Target Neighborhood Hits	174	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

FRAS1_MOUSE
NC score	0.031886 (rank : 520)	θ value	4.03905 (rank : 320)
Query Neighborhood Hits	472	Target Neighborhood Hits	747	Shared Neighborhood Hits	38
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

VPS41_MOUSE
NC score	0.031352 (rank : 521)	θ value	1.81305 (rank : 263)
Query Neighborhood Hits	472	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

ASH2L_MOUSE
NC score	0.031342 (rank : 522)	θ value	1.38821 (rank : 231)
Query Neighborhood Hits	472	Target Neighborhood Hits	40	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X20, Q3UIF9, Q9Z2X4	Gene names	Ash2l
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

AAK1_HUMAN
NC score	0.031053 (rank : 523)	θ value	0.0563607 (rank : 118)
Query Neighborhood Hits	472	Target Neighborhood Hits	1077	Shared Neighborhood Hits	87
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ZCH10_HUMAN
NC score	0.030873 (rank : 524)	θ value	5.27518 (rank : 373)
Query Neighborhood Hits	472	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ASH2L_HUMAN
NC score	0.030843 (rank : 525)	θ value	1.38821 (rank : 230)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBL3, O60659, O60660, Q96B62	Gene names	ASH2L
Domain Architecture
Description	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein).

N4BP2_HUMAN
NC score	0.030606 (rank : 526)	θ value	4.03905 (rank : 326)
Query Neighborhood Hits	472	Target Neighborhood Hits	107	Shared Neighborhood Hits	18
SwissProt Accessions	Q86UW6, Q9NVK2, Q9P2D4	Gene names	N4BP2, B3BP, KIAA1413
Domain Architecture
Description	NEDD4-binding protein 2 (EC 3.-.-.-) (N4BP2) (BCL-3-binding protein).

SMYD5_MOUSE
NC score	0.030486 (rank : 527)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	472	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TYX3, Q3TRB2, Q91YL6	Gene names	Smyd5
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 5 (Protein NN8-4AG).

MYO15_HUMAN
NC score	0.030022 (rank : 528)	θ value	1.06291 (rank : 223)
Query Neighborhood Hits	472	Target Neighborhood Hits	671	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

HUWE1_HUMAN
NC score	0.029618 (rank : 529)	θ value	5.27518 (rank : 351)
Query Neighborhood Hits	472	Target Neighborhood Hits	443	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

ANK1_MOUSE
NC score	0.029534 (rank : 530)	θ value	8.99809 (rank : 418)
Query Neighborhood Hits	472	Target Neighborhood Hits	430	Shared Neighborhood Hits	23
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

WNK2_HUMAN
NC score	0.029363 (rank : 531)	θ value	0.0563607 (rank : 124)
Query Neighborhood Hits	472	Target Neighborhood Hits	1407	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

VWF_MOUSE
NC score	0.029346 (rank : 532)	θ value	8.99809 (rank : 469)
Query Neighborhood Hits	472	Target Neighborhood Hits	381	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

COFA1_MOUSE
NC score	0.029338 (rank : 533)	θ value	1.06291 (rank : 220)
Query Neighborhood Hits	472	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

RBM25_HUMAN
NC score	0.029258 (rank : 534)	θ value	6.88961 (rank : 408)
Query Neighborhood Hits	472	Target Neighborhood Hits	682	Shared Neighborhood Hits	53
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

NOTC2_HUMAN
NC score	0.028788 (rank : 535)	θ value	8.99809 (rank : 449)
Query Neighborhood Hits	472	Target Neighborhood Hits	1113	Shared Neighborhood Hits	86
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

IF39_MOUSE
NC score	0.028464 (rank : 536)	θ value	5.27518 (rank : 352)
Query Neighborhood Hits	472	Target Neighborhood Hits	206	Shared Neighborhood Hits	26
SwissProt Accessions	Q8JZQ9, Q922K2	Gene names	Eif3s9
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116).

SEZ6L_HUMAN
NC score	0.028342 (rank : 537)	θ value	1.38821 (rank : 246)
Query Neighborhood Hits	472	Target Neighborhood Hits	289	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ZNFX1_HUMAN
NC score	0.027162 (rank : 538)	θ value	5.27518 (rank : 374)
Query Neighborhood Hits	472	Target Neighborhood Hits	308	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TRIM8_MOUSE
NC score	0.026392 (rank : 539)	θ value	3.0926 (rank : 311)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

FGD1_HUMAN
NC score	0.026152 (rank : 540)	θ value	1.38821 (rank : 236)
Query Neighborhood Hits	472	Target Neighborhood Hits	367	Shared Neighborhood Hits	45
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

THSD1_HUMAN
NC score	0.025951 (rank : 541)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	472	Target Neighborhood Hits	136	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

SAFB2_MOUSE
NC score	0.025778 (rank : 542)	θ value	1.06291 (rank : 225)
Query Neighborhood Hits	472	Target Neighborhood Hits	581	Shared Neighborhood Hits	42
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

RN125_MOUSE
NC score	0.025778 (rank : 543)	θ value	1.38821 (rank : 243)
Query Neighborhood Hits	472	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

BSCL2_HUMAN
NC score	0.025669 (rank : 544)	θ value	4.03905 (rank : 318)
Query Neighborhood Hits	472	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

SYNG_HUMAN
NC score	0.025244 (rank : 545)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	472	Target Neighborhood Hits	160	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SMYD1_HUMAN
NC score	0.024744 (rank : 546)	θ value	6.88961 (rank : 411)
Query Neighborhood Hits	472	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

AP3B1_MOUSE
NC score	0.024508 (rank : 547)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	472	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

NOTC2_MOUSE
NC score	0.024182 (rank : 548)	θ value	6.88961 (rank : 401)
Query Neighborhood Hits	472	Target Neighborhood Hits	1069	Shared Neighborhood Hits	62
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZCH14_MOUSE
NC score	0.024082 (rank : 549)	θ value	8.99809 (rank : 470)
Query Neighborhood Hits	472	Target Neighborhood Hits	109	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VIG0, Q80TX3, Q91VU4	Gene names	Zcchc14, Kiaa0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

SMYD1_MOUSE
NC score	0.023731 (rank : 550)	θ value	6.88961 (rank : 412)
Query Neighborhood Hits	472	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

CO5A2_HUMAN
NC score	0.023443 (rank : 551)	θ value	8.99809 (rank : 428)
Query Neighborhood Hits	472	Target Neighborhood Hits	760	Shared Neighborhood Hits	69
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

ZIMP7_HUMAN
NC score	0.023330 (rank : 552)	θ value	8.99809 (rank : 472)
Query Neighborhood Hits	472	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NF64, O94790, Q659A8, Q6JKL5, Q8WTX8, Q96Q01, Q9BQH7	Gene names	ZIMP7, KIAA1886
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

AFAD_HUMAN
NC score	0.023162 (rank : 553)	θ value	1.81305 (rank : 250)
Query Neighborhood Hits	472	Target Neighborhood Hits	689	Shared Neighborhood Hits	40
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CDN1B_MOUSE
NC score	0.023113 (rank : 554)	θ value	2.36792 (rank : 267)
Query Neighborhood Hits	472	Target Neighborhood Hits	25	Shared Neighborhood Hits	7
SwissProt Accessions	P46414	Gene names	Cdkn1b
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1).

K0423_MOUSE
NC score	0.023094 (rank : 555)	θ value	1.81305 (rank : 256)
Query Neighborhood Hits	472	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

SEL1L_MOUSE
NC score	0.022767 (rank : 556)	θ value	0.813845 (rank : 212)
Query Neighborhood Hits	472	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

ITIH3_MOUSE
NC score	0.022528 (rank : 557)	θ value	1.06291 (rank : 222)
Query Neighborhood Hits	472	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q61704	Gene names	Itih3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3).

PSD4_HUMAN
NC score	0.022396 (rank : 558)	θ value	6.88961 (rank : 406)
Query Neighborhood Hits	472	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

NOTC1_MOUSE
NC score	0.022236 (rank : 559)	θ value	0.62314 (rank : 200)
Query Neighborhood Hits	472	Target Neighborhood Hits	916	Shared Neighborhood Hits	42
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PRPF3_MOUSE
NC score	0.021843 (rank : 560)	θ value	5.27518 (rank : 363)
Query Neighborhood Hits	472	Target Neighborhood Hits	74	Shared Neighborhood Hits	9
SwissProt Accessions	Q922U1, Q3TJH4, Q9D6C6	Gene names	Prpf3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3).

FOG1_HUMAN
NC score	0.021678 (rank : 561)	θ value	0.62314 (rank : 197)
Query Neighborhood Hits	472	Target Neighborhood Hits	981	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

PHC2_MOUSE
NC score	0.021550 (rank : 562)	θ value	8.99809 (rank : 450)
Query Neighborhood Hits	472	Target Neighborhood Hits	156	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QWH1, O88463, Q8K5D9	Gene names	Phc2, Edr2, Ph2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36).

REN3A_HUMAN
NC score	0.021194 (rank : 563)	θ value	5.27518 (rank : 364)
Query Neighborhood Hits	472	Target Neighborhood Hits	248	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H1J1, Q5T8C3, Q5T8C9, Q7Z6N3, Q86YK1, Q9BZI8	Gene names	UPF3A, RENT3A, UPF3
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 3A (Nonsense mRNA reducing factor 3A) (Up-frameshift suppressor 3 homolog A) (hUpf3).

PRPF3_HUMAN
NC score	0.020889 (rank : 564)	θ value	5.27518 (rank : 362)
Query Neighborhood Hits	472	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	O43395, O43446	Gene names	PRPF3, HPRP3, PRP3
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (U4/U6 snRNP 90 kDa protein) (hPrp3).

GCC2_MOUSE
NC score	0.020862 (rank : 565)	θ value	2.36792 (rank : 272)
Query Neighborhood Hits	472	Target Neighborhood Hits	1619	Shared Neighborhood Hits	95
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

DBF4_MOUSE
NC score	0.020712 (rank : 566)	θ value	2.36792 (rank : 269)
Query Neighborhood Hits	472	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZ41, Q3TQP4, Q3V1K2, Q6NSQ1, Q9CXF2	Gene names	Dbf4
Domain Architecture	No domain graphic available
Description	Protein DBF4 homolog (MuDBF4).

LRC27_HUMAN
NC score	0.020643 (rank : 567)	θ value	6.88961 (rank : 397)
Query Neighborhood Hits	472	Target Neighborhood Hits	710	Shared Neighborhood Hits	47
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

CT112_MOUSE
NC score	0.020641 (rank : 568)	θ value	8.99809 (rank : 429)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

TRI25_HUMAN
NC score	0.020558 (rank : 569)	θ value	6.88961 (rank : 415)
Query Neighborhood Hits	472	Target Neighborhood Hits	472	Shared Neighborhood Hits	28
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

SEPT9_MOUSE
NC score	0.020433 (rank : 570)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	472	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	Q80UG5, Q3URP2, Q80TM7, Q9QYX9	Gene names	Sept9, Kiaa0991, Sint1
Domain Architecture	No domain graphic available
Description	Septin-9 (SL3-3 integration site 1 protein).

TTBK1_HUMAN
NC score	0.020177 (rank : 571)	θ value	8.99809 (rank : 467)
Query Neighborhood Hits	472	Target Neighborhood Hits	1058	Shared Neighborhood Hits	74
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

PMS2_MOUSE
NC score	0.019837 (rank : 572)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P54279	Gene names	Pms2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

DYN2_MOUSE
NC score	0.019397 (rank : 573)	θ value	2.36792 (rank : 270)
Query Neighborhood Hits	472	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P39054, Q9DBE1	Gene names	Dnm2, Dyn2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM).

HCN4_HUMAN
NC score	0.019374 (rank : 574)	θ value	5.27518 (rank : 349)
Query Neighborhood Hits	472	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

SHAN2_MOUSE
NC score	0.018740 (rank : 575)	θ value	8.99809 (rank : 460)
Query Neighborhood Hits	472	Target Neighborhood Hits	446	Shared Neighborhood Hits	43
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

EDEM3_HUMAN
NC score	0.018352 (rank : 576)	θ value	1.38821 (rank : 235)
Query Neighborhood Hits	472	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

MK07_MOUSE
NC score	0.018338 (rank : 577)	θ value	0.0563607 (rank : 121)
Query Neighborhood Hits	472	Target Neighborhood Hits	1054	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

DYN2_HUMAN
NC score	0.018331 (rank : 578)	θ value	3.0926 (rank : 292)
Query Neighborhood Hits	472	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

AZI1_HUMAN
NC score	0.018320 (rank : 579)	θ value	1.81305 (rank : 251)
Query Neighborhood Hits	472	Target Neighborhood Hits	1000	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

BNC1_MOUSE
NC score	0.018291 (rank : 580)	θ value	1.06291 (rank : 219)
Query Neighborhood Hits	472	Target Neighborhood Hits	582	Shared Neighborhood Hits	18
SwissProt Accessions	O35914, O54886	Gene names	Bnc1, Bnc
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-1.

CAF1B_MOUSE
NC score	0.017955 (rank : 581)	θ value	1.38821 (rank : 233)
Query Neighborhood Hits	472	Target Neighborhood Hits	385	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

HDAC6_HUMAN
NC score	0.017932 (rank : 582)	θ value	6.88961 (rank : 394)
Query Neighborhood Hits	472	Target Neighborhood Hits	145	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

RPA1_HUMAN
NC score	0.017841 (rank : 583)	θ value	1.06291 (rank : 224)
Query Neighborhood Hits	472	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

TFP11_MOUSE
NC score	0.017566 (rank : 584)	θ value	8.99809 (rank : 465)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERA6, Q8VD06	Gene names	Tfip11, Tip39
Domain Architecture
Description	Tuftelin-interacting protein 11 (Tuftelin-interacting protein 39).

SRGP1_HUMAN
NC score	0.017170 (rank : 585)	θ value	0.813845 (rank : 213)
Query Neighborhood Hits	472	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CN004_MOUSE
NC score	0.016982 (rank : 586)	θ value	8.99809 (rank : 426)
Query Neighborhood Hits	472	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3X4, Q3USE5, Q8BUS1, Q8C011	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf4 homolog.

AN32A_MOUSE
NC score	0.016633 (rank : 587)	θ value	3.0926 (rank : 285)
Query Neighborhood Hits	472	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	O35381, P97437	Gene names	Anp32a, Anp32, Lanp
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein).

AN32C_MOUSE
NC score	0.016633 (rank : 588)	θ value	3.0926 (rank : 286)
Query Neighborhood Hits	472	Target Neighborhood Hits	254	Shared Neighborhood Hits	18
SwissProt Accessions	Q64G17	Gene names	Anp32c
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C.

CENPF_HUMAN
NC score	0.016469 (rank : 589)	θ value	3.0926 (rank : 289)
Query Neighborhood Hits	472	Target Neighborhood Hits	1932	Shared Neighborhood Hits	117
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

THAP4_MOUSE
NC score	0.016232 (rank : 590)	θ value	8.99809 (rank : 466)
Query Neighborhood Hits	472	Target Neighborhood Hits	130	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

GIPC2_MOUSE
NC score	0.016154 (rank : 591)	θ value	1.38821 (rank : 238)
Query Neighborhood Hits	472	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2H7, Q9CVG2	Gene names	Gipc2, Semcap2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain- associated protein 2) (SEMCAP-2).

DGC14_MOUSE
NC score	0.016137 (rank : 592)	θ value	6.88961 (rank : 387)
Query Neighborhood Hits	472	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

PHLPP_HUMAN
NC score	0.016126 (rank : 593)	θ value	1.38821 (rank : 241)
Query Neighborhood Hits	472	Target Neighborhood Hits	604	Shared Neighborhood Hits	61
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SYTL2_MOUSE
NC score	0.015612 (rank : 594)	θ value	8.99809 (rank : 464)
Query Neighborhood Hits	472	Target Neighborhood Hits	253	Shared Neighborhood Hits	32
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

WNK1_HUMAN
NC score	0.015458 (rank : 595)	θ value	0.813845 (rank : 218)
Query Neighborhood Hits	472	Target Neighborhood Hits	1158	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

IYD1_MOUSE
NC score	0.015379 (rank : 596)	θ value	5.27518 (rank : 353)
Query Neighborhood Hits	472	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCX8	Gene names	Iyd, Dehal1
Domain Architecture	No domain graphic available
Description	Iodotyrosine dehalogenase 1 precursor (EC 1.-.-.-) (IYD-1).

FNBP2_HUMAN
NC score	0.015299 (rank : 597)	θ value	3.0926 (rank : 294)
Query Neighborhood Hits	472	Target Neighborhood Hits	432	Shared Neighborhood Hits	34
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GP156_HUMAN
NC score	0.014962 (rank : 598)	θ value	6.88961 (rank : 393)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

LPIN3_HUMAN
NC score	0.014831 (rank : 599)	θ value	1.81305 (rank : 258)
Query Neighborhood Hits	472	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BQK8, Q5TDB9, Q9NPY8, Q9UJE5	Gene names	LPIN3, LIPN3L
Domain Architecture	No domain graphic available
Description	Lipin-3 (Lipin 3-like).

BRE1A_HUMAN
NC score	0.014685 (rank : 600)	θ value	3.0926 (rank : 288)
Query Neighborhood Hits	472	Target Neighborhood Hits	1071	Shared Neighborhood Hits	60
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

RUFY1_HUMAN
NC score	0.014652 (rank : 601)	θ value	1.81305 (rank : 262)
Query Neighborhood Hits	472	Target Neighborhood Hits	848	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CD2L5_MOUSE
NC score	0.014390 (rank : 602)	θ value	0.0563607 (rank : 120)
Query Neighborhood Hits	472	Target Neighborhood Hits	1011	Shared Neighborhood Hits	59
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

SPTN5_HUMAN
NC score	0.014357 (rank : 603)	θ value	0.279714 (rank : 166)
Query Neighborhood Hits	472	Target Neighborhood Hits	674	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

ITIH3_HUMAN
NC score	0.014268 (rank : 604)	θ value	4.03905 (rank : 324)
Query Neighborhood Hits	472	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q06033, Q99085	Gene names	ITIH3
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H3 precursor (ITI heavy chain H3) (Inter-alpha-inhibitor heavy chain 3) (Serum-derived hyaluronan-associated protein) (SHAP).

CD68_MOUSE
NC score	0.013896 (rank : 605)	θ value	8.99809 (rank : 424)
Query Neighborhood Hits	472	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P31996	Gene names	Cd68
Domain Architecture
Description	Macrosialin precursor (CD68 antigen).

TAGAP_MOUSE
NC score	0.013869 (rank : 606)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

DOK7_HUMAN
NC score	0.013857 (rank : 607)	θ value	6.88961 (rank : 388)
Query Neighborhood Hits	472	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

PSMD2_MOUSE
NC score	0.013848 (rank : 608)	θ value	8.99809 (rank : 455)
Query Neighborhood Hits	472	Target Neighborhood Hits	147	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

ACD_MOUSE
NC score	0.013829 (rank : 609)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	472	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q5EE38, Q3TBB1, Q3TUR7, Q3UKL6, Q3V3Y1, Q99KF8	Gene names	Acd
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein.

POP1_HUMAN
NC score	0.013823 (rank : 610)	θ value	8.99809 (rank : 453)
Query Neighborhood Hits	472	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q99575, Q15037	Gene names	POP1, KIAA0061
Domain Architecture
Description	Ribonucleases P/MRP protein subunit POP1 (EC 3.1.26.5) (hPOP1).

AP3D1_MOUSE
NC score	0.013814 (rank : 611)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	472	Target Neighborhood Hits	144	Shared Neighborhood Hits	22
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

OSBL3_HUMAN
NC score	0.013654 (rank : 612)	θ value	0.813845 (rank : 209)
Query Neighborhood Hits	472	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

CYTSA_HUMAN
NC score	0.013641 (rank : 613)	θ value	3.0926 (rank : 290)
Query Neighborhood Hits	472	Target Neighborhood Hits	1138	Shared Neighborhood Hits	75
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

UBP35_HUMAN
NC score	0.013442 (rank : 614)	θ value	3.0926 (rank : 312)
Query Neighborhood Hits	472	Target Neighborhood Hits	223	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

NNP1_HUMAN
NC score	0.013337 (rank : 615)	θ value	5.27518 (rank : 359)
Query Neighborhood Hits	472	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P56182, Q9NST5	Gene names	NNP1, NOP52
Domain Architecture
Description	NNP-1 protein (Novel nuclear protein 1) (Nucleolar protein Nop52) (D21S2056E).

AN32A_HUMAN
NC score	0.013122 (rank : 616)	θ value	5.27518 (rank : 341)
Query Neighborhood Hits	472	Target Neighborhood Hits	234	Shared Neighborhood Hits	13
SwissProt Accessions	P39687	Gene names	ANP32A, C15orf1, LANP, MAPM, PHAP1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member A (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Acidic nuclear phosphoprotein pp32) (Leucine-rich acidic nuclear protein) (Lanp) (Putative HLA-DR-associated protein I) (PHAPI) (Mapmodulin).

CD2L5_HUMAN
NC score	0.013007 (rank : 617)	θ value	0.0252991 (rank : 105)
Query Neighborhood Hits	472	Target Neighborhood Hits	987	Shared Neighborhood Hits	45
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

MINK1_HUMAN
NC score	0.012879 (rank : 618)	θ value	0.279714 (rank : 159)
Query Neighborhood Hits	472	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ITB2_HUMAN
NC score	0.012853 (rank : 619)	θ value	4.03905 (rank : 323)
Query Neighborhood Hits	472	Target Neighborhood Hits	282	Shared Neighborhood Hits	17
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

TNNI3_MOUSE
NC score	0.012743 (rank : 620)	θ value	5.27518 (rank : 372)
Query Neighborhood Hits	472	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P48787	Gene names	Tnni3
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

FOG2_MOUSE
NC score	0.012534 (rank : 621)	θ value	0.365318 (rank : 171)
Query Neighborhood Hits	472	Target Neighborhood Hits	714	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

GAK_HUMAN
NC score	0.012220 (rank : 622)	θ value	2.36792 (rank : 271)
Query Neighborhood Hits	472	Target Neighborhood Hits	1028	Shared Neighborhood Hits	48
SwissProt Accessions	O14976, Q9BVY6	Gene names	GAK
Domain Architecture
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MK07_HUMAN
NC score	0.012098 (rank : 623)	θ value	3.0926 (rank : 300)
Query Neighborhood Hits	472	Target Neighborhood Hits	1087	Shared Neighborhood Hits	71
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

TNNI3_HUMAN
NC score	0.012093 (rank : 624)	θ value	6.88961 (rank : 414)
Query Neighborhood Hits	472	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	P19429	Gene names	TNNI3, TNNC1
Domain Architecture
Description	Troponin I, cardiac muscle (Cardiac troponin I).

HS105_HUMAN
NC score	0.011942 (rank : 625)	θ value	5.27518 (rank : 350)
Query Neighborhood Hits	472	Target Neighborhood Hits	209	Shared Neighborhood Hits	27
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

JHD2B_HUMAN
NC score	0.011885 (rank : 626)	θ value	8.99809 (rank : 438)
Query Neighborhood Hits	472	Target Neighborhood Hits	171	Shared Neighborhood Hits	22
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

MEFV_HUMAN
NC score	0.011863 (rank : 627)	θ value	5.27518 (rank : 355)
Query Neighborhood Hits	472	Target Neighborhood Hits	431	Shared Neighborhood Hits	40
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

FYV1_MOUSE
NC score	0.011624 (rank : 628)	θ value	8.99809 (rank : 433)
Query Neighborhood Hits	472	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

SEM6C_HUMAN
NC score	0.011534 (rank : 629)	θ value	0.365318 (rank : 181)
Query Neighborhood Hits	472	Target Neighborhood Hits	117	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

CCNT2_HUMAN
NC score	0.011507 (rank : 630)	θ value	8.99809 (rank : 423)
Query Neighborhood Hits	472	Target Neighborhood Hits	84	Shared Neighborhood Hits	12
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

FLIP1_HUMAN
NC score	0.011428 (rank : 631)	θ value	8.99809 (rank : 432)
Query Neighborhood Hits	472	Target Neighborhood Hits	1405	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

PSMD2_HUMAN
NC score	0.011225 (rank : 632)	θ value	8.99809 (rank : 454)
Query Neighborhood Hits	472	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

COKA1_HUMAN
NC score	0.011051 (rank : 633)	θ value	1.38821 (rank : 234)
Query Neighborhood Hits	472	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

FBXL2_MOUSE
NC score	0.010596 (rank : 634)	θ value	8.99809 (rank : 431)
Query Neighborhood Hits	472	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

APLP1_HUMAN
NC score	0.010567 (rank : 635)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	472	Target Neighborhood Hits	85	Shared Neighborhood Hits	14
SwissProt Accessions	P51693, O00113, Q96A92	Gene names	APLP1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

MRC1_MOUSE
NC score	0.010517 (rank : 636)	θ value	2.36792 (rank : 275)
Query Neighborhood Hits	472	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q61830, Q8C502	Gene names	Mrc1
Domain Architecture	No domain graphic available
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

GET1_HUMAN
NC score	0.010430 (rank : 637)	θ value	8.99809 (rank : 434)
Query Neighborhood Hits	472	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95210	Gene names	ames=GENX-3414
Domain Architecture
Description	Genethonin-1.

FARP2_HUMAN
NC score	0.010308 (rank : 638)	θ value	6.88961 (rank : 390)
Query Neighborhood Hits	472	Target Neighborhood Hits	240	Shared Neighborhood Hits	23
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MCRS1_HUMAN
NC score	0.010192 (rank : 639)	θ value	8.99809 (rank : 445)
Query Neighborhood Hits	472	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EZ8, O14742, O75497, Q6VN53	Gene names	MCRS1, MSP58
Domain Architecture
Description	Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle- regulated factor p78) (MCRS2).

RUFY1_MOUSE
NC score	0.010078 (rank : 640)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	472	Target Neighborhood Hits	765	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

CD4_HUMAN
NC score	0.009820 (rank : 641)	θ value	6.88961 (rank : 383)
Query Neighborhood Hits	472	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

PTN22_MOUSE
NC score	0.009780 (rank : 642)	θ value	8.99809 (rank : 456)
Query Neighborhood Hits	472	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

HIF1A_MOUSE
NC score	0.009636 (rank : 643)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	472	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SORC3_MOUSE
NC score	0.009536 (rank : 644)	θ value	3.0926 (rank : 307)
Query Neighborhood Hits	472	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI51, Q9CTR4	Gene names	Sorcs3
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

AAKG2_HUMAN
NC score	0.009440 (rank : 645)	θ value	5.27518 (rank : 340)
Query Neighborhood Hits	472	Target Neighborhood Hits	56	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGJ0, Q53Y07, Q6NUI0, Q75MP4, Q9NUZ9, Q9UDN8, Q9ULX8	Gene names	PRKAG2
Domain Architecture
Description	5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma-2 chain) (AMPK gamma2) (H91620p).

SNX1_MOUSE
NC score	0.009376 (rank : 646)	θ value	3.0926 (rank : 306)
Query Neighborhood Hits	472	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WV80, Q9EQZ9	Gene names	Snx1
Domain Architecture
Description	Sorting nexin-1.

STAR8_MOUSE
NC score	0.009238 (rank : 647)	θ value	6.88961 (rank : 413)
Query Neighborhood Hits	472	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

GAK_MOUSE
NC score	0.008925 (rank : 648)	θ value	6.88961 (rank : 391)
Query Neighborhood Hits	472	Target Neighborhood Hits	964	Shared Neighborhood Hits	41
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

OBSCN_HUMAN
NC score	0.008685 (rank : 649)	θ value	0.813845 (rank : 208)
Query Neighborhood Hits	472	Target Neighborhood Hits	1931	Shared Neighborhood Hits	102
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PANK1_HUMAN
NC score	0.008354 (rank : 650)	θ value	6.88961 (rank : 402)
Query Neighborhood Hits	472	Target Neighborhood Hits	75	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TE04, Q7RTX6, Q7Z495, Q8TBQ8	Gene names	PANK1, PANK
Domain Architecture
Description	Pantothenate kinase 1 (EC 2.7.1.33) (Pantothenic acid kinase 1) (hPanK1) (hPanK).

AKAP4_MOUSE
NC score	0.008045 (rank : 651)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	472	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q60662, Q60630, Q8R2G7	Gene names	Akap4, Akap82, Fsc1
Domain Architecture
Description	A-kinase anchor protein 4 precursor (Protein kinase A-anchoring protein 4) (PRKA4) (A-kinase anchor protein 82 kDa) (AKAP 82) (mAKAP82) (Major sperm fibrous sheath protein) (FSC1) (p82).

CD2L1_HUMAN
NC score	0.007963 (rank : 652)	θ value	6.88961 (rank : 382)
Query Neighborhood Hits	472	Target Neighborhood Hits	1467	Shared Neighborhood Hits	69
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

USH2A_MOUSE
NC score	0.007514 (rank : 653)	θ value	8.99809 (rank : 468)
Query Neighborhood Hits	472	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LIPA3_MOUSE
NC score	0.007101 (rank : 654)	θ value	8.99809 (rank : 442)
Query Neighborhood Hits	472	Target Neighborhood Hits	636	Shared Neighborhood Hits	39
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRP1B_MOUSE
NC score	0.006871 (rank : 655)	θ value	8.99809 (rank : 443)
Query Neighborhood Hits	472	Target Neighborhood Hits	606	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

DCHS_HUMAN
NC score	0.006594 (rank : 656)	θ value	6.88961 (rank : 386)
Query Neighborhood Hits	472	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P19113	Gene names	HDC
Domain Architecture
Description	Histidine decarboxylase (EC 4.1.1.22) (HDC).

PTPRB_HUMAN
NC score	0.006195 (rank : 657)	θ value	0.813845 (rank : 210)
Query Neighborhood Hits	472	Target Neighborhood Hits	242	Shared Neighborhood Hits	7
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

MAST1_MOUSE
NC score	0.006000 (rank : 658)	θ value	0.163984 (rank : 147)
Query Neighborhood Hits	472	Target Neighborhood Hits	1123	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

M4K4_MOUSE
NC score	0.005751 (rank : 659)	θ value	3.0926 (rank : 299)
Query Neighborhood Hits	472	Target Neighborhood Hits	1560	Shared Neighborhood Hits	72
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

LRP1B_HUMAN
NC score	0.005058 (rank : 660)	θ value	5.27518 (rank : 354)
Query Neighborhood Hits	472	Target Neighborhood Hits	602	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ARVC_HUMAN
NC score	0.004945 (rank : 661)	θ value	8.99809 (rank : 419)
Query Neighborhood Hits	472	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

LRP1_HUMAN
NC score	0.004873 (rank : 662)	θ value	8.99809 (rank : 444)
Query Neighborhood Hits	472	Target Neighborhood Hits	617	Shared Neighborhood Hits	20
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PIWL2_MOUSE
NC score	0.004490 (rank : 663)	θ value	8.99809 (rank : 452)
Query Neighborhood Hits	472	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CDG1, Q3TQE8, Q99MV6, Q9JMB6	Gene names	Piwil2, Mili
Domain Architecture	No domain graphic available
Description	Piwi-like protein 2.

MARK4_MOUSE
NC score	0.004469 (rank : 664)	θ value	0.163984 (rank : 146)
Query Neighborhood Hits	472	Target Neighborhood Hits	898	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MARK4_HUMAN
NC score	0.003446 (rank : 665)	θ value	0.813845 (rank : 206)
Query Neighborhood Hits	472	Target Neighborhood Hits	886	Shared Neighborhood Hits	26
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

S6A16_HUMAN
NC score	0.002716 (rank : 666)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	472	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZN6, Q9Y5I9	Gene names	SLC6A16, NTT5
Domain Architecture
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 (Solute carrier family 6 member 16).

ZN507_HUMAN
NC score	0.002468 (rank : 667)	θ value	0.279714 (rank : 167)
Query Neighborhood Hits	472	Target Neighborhood Hits	739	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TCN5	Gene names	ZNF507
Domain Architecture	No domain graphic available
Description	Zinc finger protein 507.

SNAI_HUMAN
NC score	0.001471 (rank : 668)	θ value	0.163984 (rank : 149)
Query Neighborhood Hits	472	Target Neighborhood Hits	708	Shared Neighborhood Hits	19
SwissProt Accessions	O95863, Q9P113, Q9UBP7, Q9UHH7	Gene names	SNAI1, SNAH
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

ZN746_HUMAN
NC score	0.001238 (rank : 669)	θ value	0.365318 (rank : 185)
Query Neighborhood Hits	472	Target Neighborhood Hits	745	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NUN9	Gene names	ZNF746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

GRAD_MOUSE
NC score	0.001156 (rank : 670)	θ value	4.03905 (rank : 321)
Query Neighborhood Hits	472	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

BOC_HUMAN
NC score	0.000141 (rank : 671)	θ value	5.27518 (rank : 344)
Query Neighborhood Hits	472	Target Neighborhood Hits	543	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

HLXB9_HUMAN
NC score	0.000051 (rank : 672)	θ value	1.38821 (rank : 239)
Query Neighborhood Hits	472	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	P50219, Q9Y648	Gene names	HLXB9
Domain Architecture
Description	Homeobox protein HB9.

ZN746_MOUSE
NC score	-0.000555 (rank : 673)	θ value	3.0926 (rank : 316)
Query Neighborhood Hits	472	Target Neighborhood Hits	748	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U133	Gene names	Znf746, Zfp746
Domain Architecture	No domain graphic available
Description	Zinc finger protein 746.

M3KL4_HUMAN
NC score	-0.000595 (rank : 674)	θ value	6.88961 (rank : 398)
Query Neighborhood Hits	472	Target Neighborhood Hits	1087	Shared Neighborhood Hits	36
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

SNAI_MOUSE
NC score	-0.000629 (rank : 675)	θ value	3.0926 (rank : 305)
Query Neighborhood Hits	472	Target Neighborhood Hits	696	Shared Neighborhood Hits	18
SwissProt Accessions	Q02085	Gene names	Snai1, Sna
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

BCL6_HUMAN
NC score	-0.000902 (rank : 676)	θ value	8.99809 (rank : 420)
Query Neighborhood Hits	472	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZBTB1_HUMAN
NC score	-0.002392 (rank : 677)	θ value	4.03905 (rank : 339)
Query Neighborhood Hits	472	Target Neighborhood Hits	805	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y2K1, Q86SW8	Gene names	ZBTB1, KIAA0997
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 1.

ZFP37_MOUSE
NC score	-0.002528 (rank : 678)	θ value	8.99809 (rank : 471)
Query Neighborhood Hits	472	Target Neighborhood Hits	906	Shared Neighborhood Hits	52
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZBT24_MOUSE
NC score	-0.003123 (rank : 679)	θ value	3.0926 (rank : 314)
Query Neighborhood Hits	472	Target Neighborhood Hits	894	Shared Neighborhood Hits	29
SwissProt Accessions	Q80X44, Q3UIB7, Q7TPC4, Q8CJC9	Gene names	Zbtb24, Bif1, Bsg1, Znf450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1).

ZN555_HUMAN
NC score	-0.003279 (rank : 680)	θ value	6.88961 (rank : 417)
Query Neighborhood Hits	472	Target Neighborhood Hits	741	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEP9, Q8NA46, Q96MP1	Gene names	ZNF555
Domain Architecture	No domain graphic available
Description	Zinc finger protein 555.

PRDM7_HUMAN
NC score	-0.003676 (rank : 681)	θ value	5.27518 (rank : 361)
Query Neighborhood Hits	472	Target Neighborhood Hits	697	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NQW5, Q9NQW4	Gene names	PRDM7, PFM4
Domain Architecture
Description	PR domain zinc finger protein 7 (PR domain-containing protein 7).

ZBT17_HUMAN
NC score	-0.003728 (rank : 682)	θ value	4.03905 (rank : 338)
Query Neighborhood Hits	472	Target Neighborhood Hits	925	Shared Neighborhood Hits	32
SwissProt Accessions	Q13105, Q15932, Q5JYB2, Q9NUC9	Gene names	ZBTB17, MIZ1, ZNF151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Myc-interacting zinc finger protein) (Miz-1 protein).

ZN256_HUMAN
NC score	-0.003824 (rank : 683)	θ value	3.0926 (rank : 315)
Query Neighborhood Hits	472	Target Neighborhood Hits	748	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2P7, Q9BV71	Gene names	ZNF256, BMZF3
Domain Architecture	No domain graphic available
Description	Zinc finger protein 256 (Bone marrow zinc finger 3) (BMZF-3).

OPRM_HUMAN
NC score	-0.008447 (rank : 684)	θ value	4.03905 (rank : 327)
Query Neighborhood Hits	472	Target Neighborhood Hits	900	Shared Neighborhood Hits	2
SwissProt Accessions	P35372, Q12930, Q7Z2D8, Q9UCZ4, Q9UN57	Gene names	OPRM1, MOR1
Domain Architecture
Description	Mu-type opioid receptor (MOR-1).