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Network neighborhood for query Sequence : CXCC1_HUMAN

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CXCC1_HUMAN
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CXCC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	143	Target Neighborhood Hits	143	Shared Neighborhood Hits	143
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	0 (rank : 2)	NC score	0.992935 (rank : 2)
Query Neighborhood Hits	143	Target Neighborhood Hits	124	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MBD1_MOUSE
θ value	6.00763e-12 (rank : 3)	NC score	0.427119 (rank : 14)
Query Neighborhood Hits	143	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MBD1_HUMAN
θ value	1.02475e-11 (rank : 4)	NC score	0.432665 (rank : 13)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

DIDO1_HUMAN
θ value	8.67504e-11 (rank : 5)	NC score	0.322337 (rank : 29)
Query Neighborhood Hits	143	Target Neighborhood Hits	960	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

K1718_MOUSE
θ value	1.47974e-10 (rank : 6)	NC score	0.499871 (rank : 3)
Query Neighborhood Hits	143	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF2_MOUSE
θ value	1.47974e-10 (rank : 7)	NC score	0.497358 (rank : 4)
Query Neighborhood Hits	143	Target Neighborhood Hits	241	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_HUMAN
θ value	2.52405e-10 (rank : 8)	NC score	0.496720 (rank : 5)
Query Neighborhood Hits	143	Target Neighborhood Hits	208	Shared Neighborhood Hits	49
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

K1718_HUMAN
θ value	4.30538e-10 (rank : 9)	NC score	0.495115 (rank : 6)
Query Neighborhood Hits	143	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_MOUSE
θ value	1.25267e-09 (rank : 10)	NC score	0.489937 (rank : 7)
Query Neighborhood Hits	143	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_HUMAN
θ value	2.13673e-09 (rank : 11)	NC score	0.489845 (rank : 8)
Query Neighborhood Hits	143	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

BPTF_HUMAN
θ value	4.76016e-09 (rank : 12)	NC score	0.299233 (rank : 34)
Query Neighborhood Hits	143	Target Neighborhood Hits	786	Shared Neighborhood Hits	73
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

HRX_HUMAN
θ value	2.36244e-08 (rank : 13)	NC score	0.282029 (rank : 38)
Query Neighborhood Hits	143	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

PHF3_HUMAN
θ value	5.26297e-08 (rank : 14)	NC score	0.330188 (rank : 26)
Query Neighborhood Hits	143	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

MLL4_HUMAN
θ value	6.87365e-08 (rank : 15)	NC score	0.283353 (rank : 37)
Query Neighborhood Hits	143	Target Neighborhood Hits	722	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

FXL19_HUMAN
θ value	2.61198e-07 (rank : 16)	NC score	0.350134 (rank : 21)
Query Neighborhood Hits	143	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
θ value	2.61198e-07 (rank : 17)	NC score	0.345190 (rank : 22)
Query Neighborhood Hits	143	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

JHD1B_HUMAN
θ value	4.45536e-07 (rank : 18)	NC score	0.444275 (rank : 12)
Query Neighborhood Hits	143	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	4.45536e-07 (rank : 19)	NC score	0.444690 (rank : 11)
Query Neighborhood Hits	143	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

DNMT1_HUMAN
θ value	9.92553e-07 (rank : 20)	NC score	0.306256 (rank : 33)
Query Neighborhood Hits	143	Target Neighborhood Hits	401	Shared Neighborhood Hits	32
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DNMT1_MOUSE
θ value	9.92553e-07 (rank : 21)	NC score	0.322895 (rank : 28)
Query Neighborhood Hits	143	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

TAF3_MOUSE
θ value	9.92553e-07 (rank : 22)	NC score	0.352575 (rank : 20)
Query Neighborhood Hits	143	Target Neighborhood Hits	463	Shared Neighborhood Hits	70
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

JHD1A_HUMAN
θ value	1.29631e-06 (rank : 23)	NC score	0.445632 (rank : 10)
Query Neighborhood Hits	143	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
θ value	1.29631e-06 (rank : 24)	NC score	0.445702 (rank : 9)
Query Neighborhood Hits	143	Target Neighborhood Hits	134	Shared Neighborhood Hits	36
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

TAF3_HUMAN
θ value	1.69304e-06 (rank : 25)	NC score	0.352759 (rank : 19)
Query Neighborhood Hits	143	Target Neighborhood Hits	568	Shared Neighborhood Hits	70
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ING1_HUMAN
θ value	3.77169e-06 (rank : 26)	NC score	0.382024 (rank : 15)
Query Neighborhood Hits	143	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_MOUSE
θ value	3.77169e-06 (rank : 27)	NC score	0.365597 (rank : 17)
Query Neighborhood Hits	143	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING1_MOUSE
θ value	4.92598e-06 (rank : 28)	NC score	0.381430 (rank : 16)
Query Neighborhood Hits	143	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_HUMAN
θ value	8.40245e-06 (rank : 29)	NC score	0.362050 (rank : 18)
Query Neighborhood Hits	143	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

BAZ1A_HUMAN
θ value	0.00020696 (rank : 30)	NC score	0.197162 (rank : 46)
Query Neighborhood Hits	143	Target Neighborhood Hits	693	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

ING3_HUMAN
θ value	0.00020696 (rank : 31)	NC score	0.337835 (rank : 23)
Query Neighborhood Hits	143	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING4_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.336851 (rank : 24)
Query Neighborhood Hits	143	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	0.000270298 (rank : 33)	NC score	0.335168 (rank : 25)
Query Neighborhood Hits	143	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING3_MOUSE
θ value	0.000602161 (rank : 34)	NC score	0.328904 (rank : 27)
Query Neighborhood Hits	143	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING5_HUMAN
θ value	0.000602161 (rank : 35)	NC score	0.316925 (rank : 31)
Query Neighborhood Hits	143	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	0.000602161 (rank : 36)	NC score	0.315294 (rank : 32)
Query Neighborhood Hits	143	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

PHF13_HUMAN
θ value	0.000786445 (rank : 37)	NC score	0.289807 (rank : 35)
Query Neighborhood Hits	143	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
θ value	0.00134147 (rank : 38)	NC score	0.287882 (rank : 36)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

BAZ2A_MOUSE
θ value	0.00298849 (rank : 39)	NC score	0.164956 (rank : 50)
Query Neighborhood Hits	143	Target Neighborhood Hits	744	Shared Neighborhood Hits	51
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CXXC6_HUMAN
θ value	0.00509761 (rank : 40)	NC score	0.199200 (rank : 45)
Query Neighborhood Hits	143	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

JAD1A_HUMAN
θ value	0.00509761 (rank : 41)	NC score	0.217778 (rank : 41)
Query Neighborhood Hits	143	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

BAZ2A_HUMAN
θ value	0.00869519 (rank : 42)	NC score	0.163037 (rank : 54)
Query Neighborhood Hits	143	Target Neighborhood Hits	780	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

C8AP2_HUMAN
θ value	0.0193708 (rank : 43)	NC score	0.087930 (rank : 87)
Query Neighborhood Hits	143	Target Neighborhood Hits	548	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

SOX13_MOUSE
θ value	0.0193708 (rank : 44)	NC score	0.042364 (rank : 147)
Query Neighborhood Hits	143	Target Neighborhood Hits	495	Shared Neighborhood Hits	10
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

BAZ1B_HUMAN
θ value	0.0252991 (rank : 45)	NC score	0.171308 (rank : 49)
Query Neighborhood Hits	143	Target Neighborhood Hits	701	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

PHF20_HUMAN
θ value	0.0252991 (rank : 46)	NC score	0.200841 (rank : 43)
Query Neighborhood Hits	143	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	0.0252991 (rank : 47)	NC score	0.201555 (rank : 42)
Query Neighborhood Hits	143	Target Neighborhood Hits	513	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CN130_HUMAN
θ value	0.0431538 (rank : 48)	NC score	0.219509 (rank : 40)
Query Neighborhood Hits	143	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

UHRF1_HUMAN
θ value	0.0431538 (rank : 49)	NC score	0.147255 (rank : 59)
Query Neighborhood Hits	143	Target Neighborhood Hits	272	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BAZ1B_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.176667 (rank : 48)
Query Neighborhood Hits	143	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

JAD1D_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.164102 (rank : 51)
Query Neighborhood Hits	143	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

CN130_MOUSE
θ value	0.0961366 (rank : 52)	NC score	0.219997 (rank : 39)
Query Neighborhood Hits	143	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

MOR2A_MOUSE
θ value	0.0961366 (rank : 53)	NC score	0.040598 (rank : 148)
Query Neighborhood Hits	143	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

PHF1_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.150465 (rank : 57)
Query Neighborhood Hits	143	Target Neighborhood Hits	117	Shared Neighborhood Hits	36
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.150373 (rank : 58)
Query Neighborhood Hits	143	Target Neighborhood Hits	116	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

INGX_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.320596 (rank : 30)
Query Neighborhood Hits	143	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

JAD1D_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.177041 (rank : 47)
Query Neighborhood Hits	143	Target Neighborhood Hits	147	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

RSF1_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.144656 (rank : 62)
Query Neighborhood Hits	143	Target Neighborhood Hits	539	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MLL2_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.145078 (rank : 61)
Query Neighborhood Hits	143	Target Neighborhood Hits	1788	Shared Neighborhood Hits	89
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

BAZ2B_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.130900 (rank : 66)
Query Neighborhood Hits	143	Target Neighborhood Hits	803	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

JAD1C_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.163831 (rank : 52)
Query Neighborhood Hits	143	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.163499 (rank : 53)
Query Neighborhood Hits	143	Target Neighborhood Hits	164	Shared Neighborhood Hits	57
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

DEND_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.051062 (rank : 142)
Query Neighborhood Hits	143	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

TCF19_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.199666 (rank : 44)
Query Neighborhood Hits	143	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

TNIK_HUMAN
θ value	0.47712 (rank : 65)	NC score	0.011420 (rank : 187)
Query Neighborhood Hits	143	Target Neighborhood Hits	1570	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

PHX2B_HUMAN
θ value	0.62314 (rank : 66)	NC score	0.012431 (rank : 182)
Query Neighborhood Hits	143	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	0.62314 (rank : 67)	NC score	0.012431 (rank : 183)
Query Neighborhood Hits	143	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

MYST4_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.118406 (rank : 75)
Query Neighborhood Hits	143	Target Neighborhood Hits	671	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.114559 (rank : 77)
Query Neighborhood Hits	143	Target Neighborhood Hits	416	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RIMS2_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.038544 (rank : 150)
Query Neighborhood Hits	143	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

SOX13_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.036233 (rank : 152)
Query Neighborhood Hits	143	Target Neighborhood Hits	464	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

DPF1_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.144391 (rank : 63)
Query Neighborhood Hits	143	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.129962 (rank : 67)
Query Neighborhood Hits	143	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EVPL_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.021922 (rank : 168)
Query Neighborhood Hits	143	Target Neighborhood Hits	895	Shared Neighborhood Hits	27
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

KI20A_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.019112 (rank : 172)
Query Neighborhood Hits	143	Target Neighborhood Hits	321	Shared Neighborhood Hits	8
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

MTF2_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.160453 (rank : 55)
Query Neighborhood Hits	143	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.159485 (rank : 56)
Query Neighborhood Hits	143	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

REQU_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.128276 (rank : 70)
Query Neighborhood Hits	143	Target Neighborhood Hits	523	Shared Neighborhood Hits	43
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

IF3A_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.032737 (rank : 156)
Query Neighborhood Hits	143	Target Neighborhood Hits	875	Shared Neighborhood Hits	32
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

LRC27_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.033100 (rank : 155)
Query Neighborhood Hits	143	Target Neighborhood Hits	710	Shared Neighborhood Hits	30
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

RIMS2_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.039905 (rank : 149)
Query Neighborhood Hits	143	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SULF2_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.023599 (rank : 164)
Query Neighborhood Hits	143	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

TNIP3_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.027777 (rank : 161)
Query Neighborhood Hits	143	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

UHRF1_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.129152 (rank : 68)
Query Neighborhood Hits	143	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

IF3A_MOUSE
θ value	1.81305 (rank : 85)	NC score	0.033853 (rank : 153)
Query Neighborhood Hits	143	Target Neighborhood Hits	871	Shared Neighborhood Hits	34
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

RBBP6_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.054567 (rank : 126)
Query Neighborhood Hits	143	Target Neighborhood Hits	1014	Shared Neighborhood Hits	36
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REQU_MOUSE
θ value	1.81305 (rank : 87)	NC score	0.125052 (rank : 71)
Query Neighborhood Hits	143	Target Neighborhood Hits	519	Shared Neighborhood Hits	42
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SFR15_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.033253 (rank : 154)
Query Neighborhood Hits	143	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

DEND_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.043625 (rank : 146)
Query Neighborhood Hits	143	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

PKCB1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.122946 (rank : 74)
Query Neighborhood Hits	143	Target Neighborhood Hits	488	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

COT1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.006553 (rank : 195)
Query Neighborhood Hits	143	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

PF21A_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.136376 (rank : 65)
Query Neighborhood Hits	143	Target Neighborhood Hits	285	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

SYBU_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.031928 (rank : 157)
Query Neighborhood Hits	143	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

TRHY_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.018557 (rank : 174)
Query Neighborhood Hits	143	Target Neighborhood Hits	1385	Shared Neighborhood Hits	33
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

CCD46_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.018632 (rank : 173)
Query Neighborhood Hits	143	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CF096_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.020725 (rank : 170)
Query Neighborhood Hits	143	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWS8, Q5SZ48, Q5SZ83, Q6NSC5, Q96EN7	Gene names	C6orf96
Domain Architecture	No domain graphic available
Description	Protein C6orf96.

DGKZ_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.006277 (rank : 197)
Query Neighborhood Hits	143	Target Neighborhood Hits	542	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

LAMA1_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.004765 (rank : 200)
Query Neighborhood Hits	143	Target Neighborhood Hits	804	Shared Neighborhood Hits	11
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MLL3_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.123852 (rank : 73)
Query Neighborhood Hits	143	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.128433 (rank : 69)
Query Neighborhood Hits	143	Target Neighborhood Hits	1399	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

THOC2_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.058989 (rank : 110)
Query Neighborhood Hits	143	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

E2AK4_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.005833 (rank : 198)
Query Neighborhood Hits	143	Target Neighborhood Hits	1012	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

K1H2_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.001874 (rank : 204)
Query Neighborhood Hits	143	Target Neighborhood Hits	492	Shared Neighborhood Hits	12
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

MINK1_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.006644 (rank : 194)
Query Neighborhood Hits	143	Target Neighborhood Hits	1477	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.006932 (rank : 192)
Query Neighborhood Hits	143	Target Neighborhood Hits	1451	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MRCKG_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.002067 (rank : 203)
Query Neighborhood Hits	143	Target Neighborhood Hits	1519	Shared Neighborhood Hits	27
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

NSD1_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.107951 (rank : 79)
Query Neighborhood Hits	143	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.115780 (rank : 76)
Query Neighborhood Hits	143	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PAK4_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.001719 (rank : 205)
Query Neighborhood Hits	143	Target Neighborhood Hits	924	Shared Neighborhood Hits	13
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

RUFY2_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.016281 (rank : 177)
Query Neighborhood Hits	143	Target Neighborhood Hits	1208	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

TR150_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.031026 (rank : 158)
Query Neighborhood Hits	143	Target Neighborhood Hits	468	Shared Neighborhood Hits	25
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

E2AK4_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.005024 (rank : 199)
Query Neighborhood Hits	143	Target Neighborhood Hits	984	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

JADE3_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.069998 (rank : 99)
Query Neighborhood Hits	143	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.068203 (rank : 101)
Query Neighborhood Hits	143	Target Neighborhood Hits	174	Shared Neighborhood Hits	48
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

LRRC6_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.017417 (rank : 175)
Query Neighborhood Hits	143	Target Neighborhood Hits	181	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

M4K4_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.006457 (rank : 196)
Query Neighborhood Hits	143	Target Neighborhood Hits	1589	Shared Neighborhood Hits	32
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.006703 (rank : 193)
Query Neighborhood Hits	143	Target Neighborhood Hits	1560	Shared Neighborhood Hits	30
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

NHS_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.030757 (rank : 159)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PF21A_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.124227 (rank : 72)
Query Neighborhood Hits	143	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PLCG1_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.007955 (rank : 191)
Query Neighborhood Hits	143	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

PYGO2_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.037986 (rank : 151)
Query Neighborhood Hits	143	Target Neighborhood Hits	189	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RASF7_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.014356 (rank : 180)
Query Neighborhood Hits	143	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

RIMS1_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.026028 (rank : 162)
Query Neighborhood Hits	143	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SGIP1_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.028280 (rank : 160)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SGIP1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.023258 (rank : 165)
Query Neighborhood Hits	143	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMC1A_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.022468 (rank : 167)
Query Neighborhood Hits	143	Target Neighborhood Hits	1346	Shared Neighborhood Hits	42
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SOX2_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.014909 (rank : 179)
Query Neighborhood Hits	143	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.014962 (rank : 178)
Query Neighborhood Hits	143	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

ACINU_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.048345 (rank : 145)
Query Neighborhood Hits	143	Target Neighborhood Hits	828	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CNTRB_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.016886 (rank : 176)
Query Neighborhood Hits	143	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CYLN2_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.010332 (rank : 188)
Query Neighborhood Hits	143	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DDX10_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.004195 (rank : 201)
Query Neighborhood Hits	143	Target Neighborhood Hits	233	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

GAK11_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.012210 (rank : 184)
Query Neighborhood Hits	143	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.012123 (rank : 185)
Query Neighborhood Hits	143	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.012103 (rank : 186)
Query Neighborhood Hits	143	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK6_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.012611 (rank : 181)
Query Neighborhood Hits	143	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GPTC8_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.025787 (rank : 163)
Query Neighborhood Hits	143	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

MTSS1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.019760 (rank : 171)
Query Neighborhood Hits	143	Target Neighborhood Hits	592	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

NU155_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.010086 (rank : 189)
Query Neighborhood Hits	143	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

RXRB_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.003933 (rank : 202)
Query Neighborhood Hits	143	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

SMC1A_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.021285 (rank : 169)
Query Neighborhood Hits	143	Target Neighborhood Hits	1384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SYBU_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.023246 (rank : 166)
Query Neighborhood Hits	143	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

TAB3_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.009913 (rank : 190)
Query Neighborhood Hits	143	Target Neighborhood Hits	273	Shared Neighborhood Hits	6
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

AIRE_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.101278 (rank : 82)
Query Neighborhood Hits	143	Target Neighborhood Hits	144	Shared Neighborhood Hits	43
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.099071 (rank : 85)
Query Neighborhood Hits	143	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BRD1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.060079 (rank : 108)
Query Neighborhood Hits	143	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.061586 (rank : 107)
Query Neighborhood Hits	143	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRPF3_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.052097 (rank : 135)
Query Neighborhood Hits	143	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CECR2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.063069 (rank : 106)
Query Neighborhood Hits	143	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.065454 (rank : 104)
Query Neighborhood Hits	143	Target Neighborhood Hits	397	Shared Neighborhood Hits	58
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.065592 (rank : 103)
Query Neighborhood Hits	143	Target Neighborhood Hits	365	Shared Neighborhood Hits	57
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.066509 (rank : 102)
Query Neighborhood Hits	143	Target Neighborhood Hits	408	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.068350 (rank : 100)
Query Neighborhood Hits	143	Target Neighborhood Hits	349	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

FBXL2_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.050274 (rank : 144)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

FBXL2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.052743 (rank : 132)
Query Neighborhood Hits	143	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FBXL7_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.063376 (rank : 105)
Query Neighborhood Hits	143	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

FXL13_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.055221 (rank : 123)
Query Neighborhood Hits	143	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

FXL14_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.053538 (rank : 130)
Query Neighborhood Hits	143	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.053689 (rank : 129)
Query Neighborhood Hits	143	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL16_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.055706 (rank : 121)
Query Neighborhood Hits	143	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

FXL20_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.056749 (rank : 116)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.056637 (rank : 117)
Query Neighborhood Hits	143	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

GCNL2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.052866 (rank : 131)
Query Neighborhood Hits	143	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.052008 (rank : 136)
Query Neighborhood Hits	143	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

JADE1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.055765 (rank : 120)
Query Neighborhood Hits	143	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.055347 (rank : 122)
Query Neighborhood Hits	143	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE2_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.052494 (rank : 133)
Query Neighborhood Hits	143	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.058040 (rank : 112)
Query Neighborhood Hits	143	Target Neighborhood Hits	560	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

LRC29_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.058997 (rank : 109)
Query Neighborhood Hits	143	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

MBD2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.051168 (rank : 141)
Query Neighborhood Hits	143	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MBD2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.051775 (rank : 137)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

MYST3_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.109479 (rank : 78)
Query Neighborhood Hits	143	Target Neighborhood Hits	772	Shared Neighborhood Hits	72
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.102092 (rank : 81)
Query Neighborhood Hits	143	Target Neighborhood Hits	688	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PCAF_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.052472 (rank : 134)
Query Neighborhood Hits	143	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PF21B_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.098760 (rank : 86)
Query Neighborhood Hits	143	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.103507 (rank : 80)
Query Neighborhood Hits	143	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.145966 (rank : 60)
Query Neighborhood Hits	143	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.142627 (rank : 64)
Query Neighborhood Hits	143	Target Neighborhood Hits	131	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.054744 (rank : 125)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.082550 (rank : 88)
Query Neighborhood Hits	143	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.080210 (rank : 90)
Query Neighborhood Hits	143	Target Neighborhood Hits	172	Shared Neighborhood Hits	45
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF14_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.074850 (rank : 95)
Query Neighborhood Hits	143	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.075512 (rank : 94)
Query Neighborhood Hits	143	Target Neighborhood Hits	342	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF22_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.051559 (rank : 139)
Query Neighborhood Hits	143	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.058142 (rank : 111)
Query Neighborhood Hits	143	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PTDSR_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.078530 (rank : 92)
Query Neighborhood Hits	143	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

PTDSR_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.080824 (rank : 89)
Query Neighborhood Hits	143	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

RBBP6_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.050385 (rank : 143)
Query Neighborhood Hits	143	Target Neighborhood Hits	1135	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SET1A_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.072457 (rank : 97)
Query Neighborhood Hits	143	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.056387 (rank : 118)
Query Neighborhood Hits	143	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.053791 (rank : 128)
Query Neighborhood Hits	143	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SKP2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.057809 (rank : 114)
Query Neighborhood Hits	143	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

SKP2_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.055844 (rank : 119)
Query Neighborhood Hits	143	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

TIF1A_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.073701 (rank : 96)
Query Neighborhood Hits	143	Target Neighborhood Hits	327	Shared Neighborhood Hits	48
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.077396 (rank : 93)
Query Neighborhood Hits	143	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.051570 (rank : 138)
Query Neighborhood Hits	143	Target Neighborhood Hits	312	Shared Neighborhood Hits	39
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.051314 (rank : 140)
Query Neighborhood Hits	143	Target Neighborhood Hits	276	Shared Neighborhood Hits	36
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.054359 (rank : 127)
Query Neighborhood Hits	143	Target Neighborhood Hits	410	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.057191 (rank : 115)
Query Neighborhood Hits	143	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.071613 (rank : 98)
Query Neighborhood Hits	143	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.078685 (rank : 91)
Query Neighborhood Hits	143	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

UHRF2_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.100482 (rank : 83)
Query Neighborhood Hits	143	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.099195 (rank : 84)
Query Neighborhood Hits	143	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZMY11_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.057844 (rank : 113)
Query Neighborhood Hits	143	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.055014 (rank : 124)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

CXCC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	143	Target Neighborhood Hits	143	Shared Neighborhood Hits	143
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
NC score	0.992935 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	143	Target Neighborhood Hits	124	Shared Neighborhood Hits	111
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

K1718_MOUSE
NC score	0.499871 (rank : 3)	θ value	1.47974e-10 (rank : 6)
Query Neighborhood Hits	143	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF2_MOUSE
NC score	0.497358 (rank : 4)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	143	Target Neighborhood Hits	241	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_HUMAN
NC score	0.496720 (rank : 5)	θ value	2.52405e-10 (rank : 8)
Query Neighborhood Hits	143	Target Neighborhood Hits	208	Shared Neighborhood Hits	49
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

K1718_HUMAN
NC score	0.495115 (rank : 6)	θ value	4.30538e-10 (rank : 9)
Query Neighborhood Hits	143	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_MOUSE
NC score	0.489937 (rank : 7)	θ value	1.25267e-09 (rank : 10)
Query Neighborhood Hits	143	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF8_HUMAN
NC score	0.489845 (rank : 8)	θ value	2.13673e-09 (rank : 11)
Query Neighborhood Hits	143	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

JHD1A_MOUSE
NC score	0.445702 (rank : 9)	θ value	1.29631e-06 (rank : 24)
Query Neighborhood Hits	143	Target Neighborhood Hits	134	Shared Neighborhood Hits	36
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

JHD1A_HUMAN
NC score	0.445632 (rank : 10)	θ value	1.29631e-06 (rank : 23)
Query Neighborhood Hits	143	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1B_MOUSE
NC score	0.444690 (rank : 11)	θ value	4.45536e-07 (rank : 19)
Query Neighborhood Hits	143	Target Neighborhood Hits	214	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

JHD1B_HUMAN
NC score	0.444275 (rank : 12)	θ value	4.45536e-07 (rank : 18)
Query Neighborhood Hits	143	Target Neighborhood Hits	178	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

MBD1_HUMAN
NC score	0.432665 (rank : 13)	θ value	1.02475e-11 (rank : 4)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD1_MOUSE
NC score	0.427119 (rank : 14)	θ value	6.00763e-12 (rank : 3)
Query Neighborhood Hits	143	Target Neighborhood Hits	72	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

ING1_HUMAN
NC score	0.382024 (rank : 15)	θ value	3.77169e-06 (rank : 26)
Query Neighborhood Hits	143	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
NC score	0.381430 (rank : 16)	θ value	4.92598e-06 (rank : 28)
Query Neighborhood Hits	143	Target Neighborhood Hits	71	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_MOUSE
NC score	0.365597 (rank : 17)	θ value	3.77169e-06 (rank : 27)
Query Neighborhood Hits	143	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING2_HUMAN
NC score	0.362050 (rank : 18)	θ value	8.40245e-06 (rank : 29)
Query Neighborhood Hits	143	Target Neighborhood Hits	101	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

TAF3_HUMAN
NC score	0.352759 (rank : 19)	θ value	1.69304e-06 (rank : 25)
Query Neighborhood Hits	143	Target Neighborhood Hits	568	Shared Neighborhood Hits	70
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TAF3_MOUSE
NC score	0.352575 (rank : 20)	θ value	9.92553e-07 (rank : 22)
Query Neighborhood Hits	143	Target Neighborhood Hits	463	Shared Neighborhood Hits	70
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

FXL19_HUMAN
NC score	0.350134 (rank : 21)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	143	Target Neighborhood Hits	147	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FXL19_MOUSE
NC score	0.345190 (rank : 22)	θ value	2.61198e-07 (rank : 17)
Query Neighborhood Hits	143	Target Neighborhood Hits	217	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

ING3_HUMAN
NC score	0.337835 (rank : 23)	θ value	0.00020696 (rank : 31)
Query Neighborhood Hits	143	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

ING4_HUMAN
NC score	0.336851 (rank : 24)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	143	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
NC score	0.335168 (rank : 25)	θ value	0.000270298 (rank : 33)
Query Neighborhood Hits	143	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

PHF3_HUMAN
NC score	0.330188 (rank : 26)	θ value	5.26297e-08 (rank : 14)
Query Neighborhood Hits	143	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ING3_MOUSE
NC score	0.328904 (rank : 27)	θ value	0.000602161 (rank : 34)
Query Neighborhood Hits	143	Target Neighborhood Hits	177	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

DNMT1_MOUSE
NC score	0.322895 (rank : 28)	θ value	9.92553e-07 (rank : 21)
Query Neighborhood Hits	143	Target Neighborhood Hits	137	Shared Neighborhood Hits	19
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

DIDO1_HUMAN
NC score	0.322337 (rank : 29)	θ value	8.67504e-11 (rank : 5)
Query Neighborhood Hits	143	Target Neighborhood Hits	960	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

INGX_HUMAN
NC score	0.320596 (rank : 30)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	143	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0U5	Gene names	INGX, ING2
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein, X-linked (Inhibitor of growth protein 2) (ING1-like tumor suppressor protein).

ING5_HUMAN
NC score	0.316925 (rank : 31)	θ value	0.000602161 (rank : 35)
Query Neighborhood Hits	143	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
NC score	0.315294 (rank : 32)	θ value	0.000602161 (rank : 36)
Query Neighborhood Hits	143	Target Neighborhood Hits	76	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

DNMT1_HUMAN
NC score	0.306256 (rank : 33)	θ value	9.92553e-07 (rank : 20)
Query Neighborhood Hits	143	Target Neighborhood Hits	401	Shared Neighborhood Hits	32
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

BPTF_HUMAN
NC score	0.299233 (rank : 34)	θ value	4.76016e-09 (rank : 12)
Query Neighborhood Hits	143	Target Neighborhood Hits	786	Shared Neighborhood Hits	73
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

PHF13_HUMAN
NC score	0.289807 (rank : 35)	θ value	0.000786445 (rank : 37)
Query Neighborhood Hits	143	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
NC score	0.287882 (rank : 36)	θ value	0.00134147 (rank : 38)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

MLL4_HUMAN
NC score	0.283353 (rank : 37)	θ value	6.87365e-08 (rank : 15)
Query Neighborhood Hits	143	Target Neighborhood Hits	722	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.282029 (rank : 38)	θ value	2.36244e-08 (rank : 13)
Query Neighborhood Hits	143	Target Neighborhood Hits	825	Shared Neighborhood Hits	71
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CN130_MOUSE
NC score	0.219997 (rank : 39)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	143	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

CN130_HUMAN
NC score	0.219509 (rank : 40)	θ value	0.0431538 (rank : 48)
Query Neighborhood Hits	143	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

JAD1A_HUMAN
NC score	0.217778 (rank : 41)	θ value	0.00509761 (rank : 41)
Query Neighborhood Hits	143	Target Neighborhood Hits	328	Shared Neighborhood Hits	79
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

PHF20_MOUSE
NC score	0.201555 (rank : 42)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	143	Target Neighborhood Hits	513	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF20_HUMAN
NC score	0.200841 (rank : 43)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	143	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

TCF19_HUMAN
NC score	0.199666 (rank : 44)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	143	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

CXXC6_HUMAN
NC score	0.199200 (rank : 45)	θ value	0.00509761 (rank : 40)
Query Neighborhood Hits	143	Target Neighborhood Hits	180	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

BAZ1A_HUMAN
NC score	0.197162 (rank : 46)	θ value	0.00020696 (rank : 30)
Query Neighborhood Hits	143	Target Neighborhood Hits	693	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

JAD1D_HUMAN
NC score	0.177041 (rank : 47)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	143	Target Neighborhood Hits	147	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

BAZ1B_MOUSE
NC score	0.176667 (rank : 48)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	143	Target Neighborhood Hits	394	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1B_HUMAN
NC score	0.171308 (rank : 49)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	143	Target Neighborhood Hits	701	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ2A_MOUSE
NC score	0.164956 (rank : 50)	θ value	0.00298849 (rank : 39)
Query Neighborhood Hits	143	Target Neighborhood Hits	744	Shared Neighborhood Hits	51
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

JAD1D_MOUSE
NC score	0.164102 (rank : 51)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	143	Target Neighborhood Hits	228	Shared Neighborhood Hits	58
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_HUMAN
NC score	0.163831 (rank : 52)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	143	Target Neighborhood Hits	187	Shared Neighborhood Hits	57
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
NC score	0.163499 (rank : 53)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	143	Target Neighborhood Hits	164	Shared Neighborhood Hits	57
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

BAZ2A_HUMAN
NC score	0.163037 (rank : 54)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	143	Target Neighborhood Hits	780	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MTF2_HUMAN
NC score	0.160453 (rank : 55)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	143	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.159485 (rank : 56)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	143	Target Neighborhood Hits	126	Shared Neighborhood Hits	48
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PHF1_HUMAN
NC score	0.150465 (rank : 57)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	143	Target Neighborhood Hits	117	Shared Neighborhood Hits	36
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.150373 (rank : 58)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	143	Target Neighborhood Hits	116	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

UHRF1_HUMAN
NC score	0.147255 (rank : 59)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	143	Target Neighborhood Hits	272	Shared Neighborhood Hits	47
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

PHF10_HUMAN
NC score	0.145966 (rank : 60)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	143	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

MLL2_HUMAN
NC score	0.145078 (rank : 61)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	143	Target Neighborhood Hits	1788	Shared Neighborhood Hits	89
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RSF1_HUMAN
NC score	0.144656 (rank : 62)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	143	Target Neighborhood Hits	539	Shared Neighborhood Hits	52
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

DPF1_HUMAN
NC score	0.144391 (rank : 63)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	143	Target Neighborhood Hits	136	Shared Neighborhood Hits	41
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

PHF10_MOUSE
NC score	0.142627 (rank : 64)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	143	Target Neighborhood Hits	131	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PF21A_MOUSE
NC score	0.136376 (rank : 65)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	143	Target Neighborhood Hits	285	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

BAZ2B_HUMAN
NC score	0.130900 (rank : 66)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	143	Target Neighborhood Hits	803	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DPF1_MOUSE
NC score	0.129962 (rank : 67)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	143	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

UHRF1_MOUSE
NC score	0.129152 (rank : 68)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	143	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

MLL3_MOUSE
NC score	0.128433 (rank : 69)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	143	Target Neighborhood Hits	1399	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

REQU_HUMAN
NC score	0.128276 (rank : 70)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	143	Target Neighborhood Hits	523	Shared Neighborhood Hits	43
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.125052 (rank : 71)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	143	Target Neighborhood Hits	519	Shared Neighborhood Hits	42
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PF21A_HUMAN
NC score	0.124227 (rank : 72)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	143	Target Neighborhood Hits	303	Shared Neighborhood Hits	56
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MLL3_HUMAN
NC score	0.123852 (rank : 73)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	143	Target Neighborhood Hits	1644	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PKCB1_HUMAN
NC score	0.122946 (rank : 74)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	143	Target Neighborhood Hits	488	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

MYST4_HUMAN
NC score	0.118406 (rank : 75)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	143	Target Neighborhood Hits	671	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NSD1_MOUSE
NC score	0.115780 (rank : 76)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	143	Target Neighborhood Hits	472	Shared Neighborhood Hits	56
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MYST4_MOUSE
NC score	0.114559 (rank : 77)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	143	Target Neighborhood Hits	416	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

MYST3_HUMAN
NC score	0.109479 (rank : 78)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	143	Target Neighborhood Hits	772	Shared Neighborhood Hits	72
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NSD1_HUMAN
NC score	0.107951 (rank : 79)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	143	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PF21B_MOUSE
NC score	0.103507 (rank : 80)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	143	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST3_MOUSE
NC score	0.102092 (rank : 81)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	143	Target Neighborhood Hits	688	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

AIRE_HUMAN
NC score	0.101278 (rank : 82)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	143	Target Neighborhood Hits	144	Shared Neighborhood Hits	43
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

UHRF2_HUMAN
NC score	0.100482 (rank : 83)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	143	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
NC score	0.099195 (rank : 84)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	143	Target Neighborhood Hits	275	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

AIRE_MOUSE
NC score	0.099071 (rank : 85)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	143	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PF21B_HUMAN
NC score	0.098760 (rank : 86)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	143	Target Neighborhood Hits	197	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

C8AP2_HUMAN
NC score	0.087930 (rank : 87)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	143	Target Neighborhood Hits	548	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PHF12_HUMAN
NC score	0.082550 (rank : 88)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	143	Target Neighborhood Hits	174	Shared Neighborhood Hits	45
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PTDSR_MOUSE
NC score	0.080824 (rank : 89)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	143	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERI5, Q80TX1	Gene names	Ptdsr, Kiaa0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor) (Apoptotic cell clearance receptor PtdSerR).

PHF12_MOUSE
NC score	0.080210 (rank : 90)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	143	Target Neighborhood Hits	172	Shared Neighborhood Hits	45
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

TRI66_MOUSE
NC score	0.078685 (rank : 91)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	143	Target Neighborhood Hits	491	Shared Neighborhood Hits	58
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PTDSR_HUMAN
NC score	0.078530 (rank : 92)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	143	Target Neighborhood Hits	22	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NYC1, Q86VY0, Q8IUM5, Q9Y4E2	Gene names	PTDSR, KIAA0585
Domain Architecture	No domain graphic available
Description	Protein PTDSR (Phosphatidylserine receptor).

TIF1A_MOUSE
NC score	0.077396 (rank : 93)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	143	Target Neighborhood Hits	307	Shared Neighborhood Hits	48
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PHF14_MOUSE
NC score	0.075512 (rank : 94)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	143	Target Neighborhood Hits	342	Shared Neighborhood Hits	54
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.074850 (rank : 95)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	143	Target Neighborhood Hits	447	Shared Neighborhood Hits	56
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

TIF1A_HUMAN
NC score	0.073701 (rank : 96)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	143	Target Neighborhood Hits	327	Shared Neighborhood Hits	48
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

SET1A_HUMAN
NC score	0.072457 (rank : 97)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	143	Target Neighborhood Hits	690	Shared Neighborhood Hits	29
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TRI66_HUMAN
NC score	0.071613 (rank : 98)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	143	Target Neighborhood Hits	479	Shared Neighborhood Hits	53
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

JADE3_HUMAN
NC score	0.069998 (rank : 99)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	143	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

CHD5_HUMAN
NC score	0.068350 (rank : 100)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	143	Target Neighborhood Hits	349	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

JADE3_MOUSE
NC score	0.068203 (rank : 101)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	143	Target Neighborhood Hits	174	Shared Neighborhood Hits	48
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

CHD4_MOUSE
NC score	0.066509 (rank : 102)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	143	Target Neighborhood Hits	408	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.065592 (rank : 103)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	143	Target Neighborhood Hits	365	Shared Neighborhood Hits	57
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD3_HUMAN
NC score	0.065454 (rank : 104)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	143	Target Neighborhood Hits	397	Shared Neighborhood Hits	58
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

FBXL7_HUMAN
NC score	0.063376 (rank : 105)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	143	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJT9, O94926	Gene names	FBXL7, FBL6, FBL7, KIAA0840
Domain Architecture
Description	F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7).

CECR2_HUMAN
NC score	0.063069 (rank : 106)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	143	Target Neighborhood Hits	543	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BRPF1_HUMAN
NC score	0.061586 (rank : 107)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	143	Target Neighborhood Hits	259	Shared Neighborhood Hits	47
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BRD1_HUMAN
NC score	0.060079 (rank : 108)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	143	Target Neighborhood Hits	188	Shared Neighborhood Hits	39
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

LRC29_HUMAN
NC score	0.058997 (rank : 109)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	143	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV35, Q9UKA0	Gene names	LRRC29, FBL9, FBXL9
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 29 (F-box/LRR-repeat protein 9) (F-box and leucine-rich repeat protein 9) (F-box protein FBL9).

THOC2_HUMAN
NC score	0.058989 (rank : 110)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	143	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

PHF22_MOUSE
NC score	0.058142 (rank : 111)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	143	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

JADE2_MOUSE
NC score	0.058040 (rank : 112)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	143	Target Neighborhood Hits	560	Shared Neighborhood Hits	54
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

ZMY11_HUMAN
NC score	0.057844 (rank : 113)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	143	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

SKP2_HUMAN
NC score	0.057809 (rank : 114)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	143	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q13309, Q8TDZ0, Q8TDZ1, Q9BV69	Gene names	SKP2, FBXL1
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (p45skp2) (F-box/LRR-repeat protein 1).

TIF1G_MOUSE
NC score	0.057191 (rank : 115)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	143	Target Neighborhood Hits	498	Shared Neighborhood Hits	45
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

FXL20_HUMAN
NC score	0.056749 (rank : 116)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q96IG2	Gene names	FBXL20, FBL2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

FXL20_MOUSE
NC score	0.056637 (rank : 117)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	143	Target Neighborhood Hits	78	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CZV8, Q8BZ95	Gene names	Fbxl20, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like).

SETD8_HUMAN
NC score	0.056387 (rank : 118)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	143	Target Neighborhood Hits	114	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SKP2_MOUSE
NC score	0.055844 (rank : 119)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	143	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

JADE1_HUMAN
NC score	0.055765 (rank : 120)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	143	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

FXL16_HUMAN
NC score	0.055706 (rank : 121)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	143	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

JADE1_MOUSE
NC score	0.055347 (rank : 122)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	143	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

FXL13_MOUSE
NC score	0.055221 (rank : 123)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	143	Target Neighborhood Hits	70	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CDU4, Q8CDE9	Gene names	Fbxl13
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 13 (F-box and leucine-rich repeat protein 13).

ZMY11_MOUSE
NC score	0.055014 (rank : 124)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

PHF11_HUMAN
NC score	0.054744 (rank : 125)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

RBBP6_MOUSE
NC score	0.054567 (rank : 126)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	143	Target Neighborhood Hits	1014	Shared Neighborhood Hits	36
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

TIF1G_HUMAN
NC score	0.054359 (rank : 127)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	143	Target Neighborhood Hits	410	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

SETD8_MOUSE
NC score	0.053791 (rank : 128)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	143	Target Neighborhood Hits	131	Shared Neighborhood Hits	16
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

FXL14_MOUSE
NC score	0.053689 (rank : 129)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	143	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BID8, Q3U2Q9, Q8R5H7, Q8VDT7, Q922N5	Gene names	Fbxl14, Fbl14, Ppa
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

FXL14_HUMAN
NC score	0.053538 (rank : 130)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	143	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1E6	Gene names	FBXL14, FBL14
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14).

GCNL2_HUMAN
NC score	0.052866 (rank : 131)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	143	Target Neighborhood Hits	159	Shared Neighborhood Hits	9
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

FBXL2_MOUSE
NC score	0.052743 (rank : 132)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	143	Target Neighborhood Hits	83	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

JADE2_HUMAN
NC score	0.052494 (rank : 133)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	143	Target Neighborhood Hits	199	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

PCAF_HUMAN
NC score	0.052472 (rank : 134)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	143	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRPF3_HUMAN
NC score	0.052097 (rank : 135)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	143	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

GCNL2_MOUSE
NC score	0.052008 (rank : 136)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	143	Target Neighborhood Hits	146	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

MBD2_MOUSE
NC score	0.051775 (rank : 137)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	143	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

TIF1B_HUMAN
NC score	0.051570 (rank : 138)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	143	Target Neighborhood Hits	312	Shared Neighborhood Hits	39
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PHF22_HUMAN
NC score	0.051559 (rank : 139)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	143	Target Neighborhood Hits	121	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

TIF1B_MOUSE
NC score	0.051314 (rank : 140)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	143	Target Neighborhood Hits	276	Shared Neighborhood Hits	36
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

MBD2_HUMAN
NC score	0.051168 (rank : 141)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	143	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

DEND_HUMAN
NC score	0.051062 (rank : 142)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	143	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O94850	Gene names	DDN, KIAA0749
Domain Architecture	No domain graphic available
Description	Dendrin.

RBBP6_HUMAN
NC score	0.050385 (rank : 143)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	143	Target Neighborhood Hits	1135	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FBXL2_HUMAN
NC score	0.050274 (rank : 144)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	143	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

ACINU_HUMAN
NC score	0.048345 (rank : 145)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	143	Target Neighborhood Hits	828	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

DEND_MOUSE
NC score	0.043625 (rank : 146)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	143	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

SOX13_MOUSE
NC score	0.042364 (rank : 147)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	143	Target Neighborhood Hits	495	Shared Neighborhood Hits	10
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

MOR2A_MOUSE
NC score	0.040598 (rank : 148)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	143	Target Neighborhood Hits	220	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

RIMS2_MOUSE
NC score	0.039905 (rank : 149)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	143	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS2_HUMAN
NC score	0.038544 (rank : 150)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	143	Target Neighborhood Hits	342	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

PYGO2_HUMAN
NC score	0.037986 (rank : 151)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	143	Target Neighborhood Hits	189	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SOX13_HUMAN
NC score	0.036233 (rank : 152)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	143	Target Neighborhood Hits	464	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

IF3A_MOUSE
NC score	0.033853 (rank : 153)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	143	Target Neighborhood Hits	871	Shared Neighborhood Hits	34
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

SFR15_HUMAN
NC score	0.033253 (rank : 154)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	143	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

LRC27_HUMAN
NC score	0.033100 (rank : 155)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	143	Target Neighborhood Hits	710	Shared Neighborhood Hits	30
SwissProt Accessions	Q9C0I9, Q5SZH6, Q5SZH8, Q5SZH9, Q86XT5, Q8N7C8, Q8NA21	Gene names	LRRC27, KIAA1674
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 27.

IF3A_HUMAN
NC score	0.032737 (rank : 156)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	143	Target Neighborhood Hits	875	Shared Neighborhood Hits	32
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

SYBU_MOUSE
NC score	0.031928 (rank : 157)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	143	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BHS8, Q3TQN7, Q401F3, Q401F4, Q571C1, Q6P1J2, Q80XH0, Q8BHS7, Q8BI27	Gene names	Sybu, Golsyn, Kiaa1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein) (m-Golsyn).

TR150_MOUSE
NC score	0.031026 (rank : 158)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	143	Target Neighborhood Hits	468	Shared Neighborhood Hits	25
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

NHS_HUMAN
NC score	0.030757 (rank : 159)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

SGIP1_HUMAN
NC score	0.028280 (rank : 160)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	143	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TNIP3_HUMAN
NC score	0.027777 (rank : 161)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	143	Target Neighborhood Hits	511	Shared Neighborhood Hits	15
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

RIMS1_HUMAN
NC score	0.026028 (rank : 162)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	143	Target Neighborhood Hits	437	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

GPTC8_HUMAN
NC score	0.025787 (rank : 163)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	143	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SULF2_MOUSE
NC score	0.023599 (rank : 164)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	143	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG0, Q8BM68, Q8BUZ4, Q8BX28, Q8BZ51, Q8C169, Q9D8E2	Gene names	Sulf2
Domain Architecture
Description	Extracellular sulfatase Sulf-2 precursor (EC 3.1.6.-) (MSulf-2).

SGIP1_MOUSE
NC score	0.023258 (rank : 165)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	143	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYBU_HUMAN
NC score	0.023246 (rank : 166)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	143	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NX95, Q5R1T1, Q5R1T2, Q5R1T3, Q5Y2M6, Q8ND49, Q8TCR6, Q9P256	Gene names	SYBU, GOLSYN, KIAA1472
Domain Architecture	No domain graphic available
Description	Syntabulin (Syntaxin-1-binding protein) (Golgi-localized syntaphilin- related protein).

SMC1A_HUMAN
NC score	0.022468 (rank : 167)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	143	Target Neighborhood Hits	1346	Shared Neighborhood Hits	42
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

EVPL_HUMAN
NC score	0.021922 (rank : 168)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	143	Target Neighborhood Hits	895	Shared Neighborhood Hits	27
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SMC1A_MOUSE
NC score	0.021285 (rank : 169)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	143	Target Neighborhood Hits	1384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

CF096_HUMAN
NC score	0.020725 (rank : 170)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	143	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWS8, Q5SZ48, Q5SZ83, Q6NSC5, Q96EN7	Gene names	C6orf96
Domain Architecture	No domain graphic available
Description	Protein C6orf96.

MTSS1_MOUSE
NC score	0.019760 (rank : 171)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	143	Target Neighborhood Hits	592	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

KI20A_HUMAN
NC score	0.019112 (rank : 172)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	143	Target Neighborhood Hits	321	Shared Neighborhood Hits	8
SwissProt Accessions	O95235	Gene names	KIF20A, RAB6KIFL
Domain Architecture
Description	Kinesin family member 20A (Rabkinesin-6) (Rab6-interacting kinesin- like protein) (GG10_2).

CCD46_MOUSE
NC score	0.018632 (rank : 173)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	143	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

TRHY_HUMAN
NC score	0.018557 (rank : 174)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	143	Target Neighborhood Hits	1385	Shared Neighborhood Hits	33
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

LRRC6_HUMAN
NC score	0.017417 (rank : 175)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	143	Target Neighborhood Hits	181	Shared Neighborhood Hits	9
SwissProt Accessions	Q86X45, Q13648, Q4G183	Gene names	LRRC6, LRTP, TSLRP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 6 (Leucine-rich testis-specific protein) (Testis-specific leucine-rich repeat protein).

CNTRB_HUMAN
NC score	0.016886 (rank : 176)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	143	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

RUFY2_HUMAN
NC score	0.016281 (rank : 177)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	143	Target Neighborhood Hits	1208	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SOX2_MOUSE
NC score	0.014962 (rank : 178)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	143	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_HUMAN
NC score	0.014909 (rank : 179)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	143	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

RASF7_HUMAN
NC score	0.014356 (rank : 180)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	143	Target Neighborhood Hits	96	Shared Neighborhood Hits	4
SwissProt Accessions	Q02833	Gene names	RASSF7, C11orf13, HRC1
Domain Architecture
Description	Ras association domain-containing protein 7 (HRAS1-related cluster protein 1).

GAK6_HUMAN
NC score	0.012611 (rank : 181)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	143	Target Neighborhood Hits	392	Shared Neighborhood Hits	11
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

PHX2B_HUMAN
NC score	0.012431 (rank : 182)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	143	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.012431 (rank : 183)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	143	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

GAK11_HUMAN
NC score	0.012210 (rank : 184)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	143	Target Neighborhood Hits	409	Shared Neighborhood Hits	11
SwissProt Accessions	P63145, Q9UKI1	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K101 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK2_HUMAN
NC score	0.012123 (rank : 185)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	143	Target Neighborhood Hits	406	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LDI9, Q9UKH5, Q9Y6I1, Q9YNA6, Q9YNB0	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K(HML-2.HOM) Gag protein) (HERV-K108 Gag protein) (HERV-K(C7) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

GAK4_HUMAN
NC score	0.012103 (rank : 186)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	143	Target Neighborhood Hits	415	Shared Neighborhood Hits	11
SwissProt Accessions	P63126, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K109 Gag protein) (HERV-K(C6) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

TNIK_HUMAN
NC score	0.011420 (rank : 187)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	143	Target Neighborhood Hits	1570	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

CYLN2_HUMAN
NC score	0.010332 (rank : 188)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	143	Target Neighborhood Hits	1004	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

NU155_HUMAN
NC score	0.010086 (rank : 189)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	143	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

TAB3_MOUSE
NC score	0.009913 (rank : 190)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	143	Target Neighborhood Hits	273	Shared Neighborhood Hits	6
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

PLCG1_MOUSE
NC score	0.007955 (rank : 191)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	143	Target Neighborhood Hits	314	Shared Neighborhood Hits	3
SwissProt Accessions	Q62077, Q6P1G1	Gene names	Plcg1, Plcg-1
Domain Architecture	No domain graphic available
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148).

MINK1_MOUSE
NC score	0.006932 (rank : 192)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	143	Target Neighborhood Hits	1451	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

M4K4_MOUSE
NC score	0.006703 (rank : 193)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	143	Target Neighborhood Hits	1560	Shared Neighborhood Hits	30
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MINK1_HUMAN
NC score	0.006644 (rank : 194)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	143	Target Neighborhood Hits	1477	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

COT1_MOUSE
NC score	0.006553 (rank : 195)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	143	Target Neighborhood Hits	160	Shared Neighborhood Hits	4
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

M4K4_HUMAN
NC score	0.006457 (rank : 196)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	143	Target Neighborhood Hits	1589	Shared Neighborhood Hits	32
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

DGKZ_MOUSE
NC score	0.006277 (rank : 197)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	143	Target Neighborhood Hits	542	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

E2AK4_HUMAN
NC score	0.005833 (rank : 198)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	143	Target Neighborhood Hits	1012	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2K8, Q69YL7, Q6DC97, Q96GN6, Q9H5K1, Q9NSQ3, Q9NSZ5, Q9UJ56	Gene names	EIF2AK4, GCN2, KIAA1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein).

E2AK4_MOUSE
NC score	0.005024 (rank : 199)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	143	Target Neighborhood Hits	984	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZ05, Q6GQT4, Q6ZPT5, Q8C5S0, Q8CIF5, Q9CT30, Q9CUV9, Q9ESB6, Q9ESB7, Q9ESB8	Gene names	Eif2ak4, Gcn2, Kiaa1338
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 2-alpha kinase 4 (EC 2.7.11.1) (GCN2-like protein) (mGCN2).

LAMA1_HUMAN
NC score	0.004765 (rank : 200)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	143	Target Neighborhood Hits	804	Shared Neighborhood Hits	11
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

DDX10_MOUSE
NC score	0.004195 (rank : 201)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	143	Target Neighborhood Hits	233	Shared Neighborhood Hits	11
SwissProt Accessions	Q80Y44	Gene names	Ddx10
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

RXRB_HUMAN
NC score	0.003933 (rank : 202)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	143	Target Neighborhood Hits	280	Shared Neighborhood Hits	8
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

MRCKG_HUMAN
NC score	0.002067 (rank : 203)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	143	Target Neighborhood Hits	1519	Shared Neighborhood Hits	27
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

K1H2_HUMAN
NC score	0.001874 (rank : 204)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	143	Target Neighborhood Hits	492	Shared Neighborhood Hits	12
SwissProt Accessions	Q14532	Gene names	KRTHA2, HHA2, HKA2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

PAK4_HUMAN
NC score	0.001719 (rank : 205)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	143	Target Neighborhood Hits	924	Shared Neighborhood Hits	13
SwissProt Accessions	O96013, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8	Gene names	PAK4, KIAA1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).